Amino acid dipepetide frequency for Human fecal virus Jorvi2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.134AlaGlu: 2.134 ± 0.964
0.0AlaPhe: 0.0 ± 0.0
2.134AlaGly: 2.134 ± 1.914
2.134AlaHis: 2.134 ± 1.19
8.538AlaIle: 8.538 ± 3.18
5.336AlaLys: 5.336 ± 1.782
1.067AlaLeu: 1.067 ± 0.8
0.0AlaMet: 0.0 ± 0.0
5.336AlaAsn: 5.336 ± 2.602
5.336AlaPro: 5.336 ± 1.863
1.067AlaGln: 1.067 ± 0.957
4.269AlaArg: 4.269 ± 1.771
5.336AlaSer: 5.336 ± 3.815
0.0AlaThr: 0.0 ± 0.0
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
4.269AlaTyr: 4.269 ± 1.253
0.0AlaXaa: 0.0 ± 0.0
Cys
1.067CysAla: 1.067 ± 0.957
1.067CysCys: 1.067 ± 0.957
1.067CysAsp: 1.067 ± 1.232
1.067CysGlu: 1.067 ± 1.232
1.067CysPhe: 1.067 ± 0.8
0.0CysGly: 0.0 ± 0.0
1.067CysHis: 1.067 ± 1.232
2.134CysIle: 2.134 ± 1.911
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.067CysAsn: 1.067 ± 0.8
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
2.134CysThr: 2.134 ± 1.599
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.202AspAla: 3.202 ± 1.482
1.067AspCys: 1.067 ± 0.8
8.538AspAsp: 8.538 ± 5.693
4.269AspGlu: 4.269 ± 4.928
5.336AspPhe: 5.336 ± 3.58
2.134AspGly: 2.134 ± 0.964
3.202AspHis: 3.202 ± 1.673
3.202AspIle: 3.202 ± 1.755
3.202AspLys: 3.202 ± 1.485
3.202AspLeu: 3.202 ± 1.61
0.0AspMet: 0.0 ± 0.0
5.336AspAsn: 5.336 ± 2.79
0.0AspPro: 0.0 ± 0.0
1.067AspGln: 1.067 ± 0.965
3.202AspArg: 3.202 ± 1.021
5.336AspSer: 5.336 ± 3.895
3.202AspThr: 3.202 ± 2.872
2.134AspVal: 2.134 ± 1.041
0.0AspTrp: 0.0 ± 0.0
6.403AspTyr: 6.403 ± 2.372
0.0AspXaa: 0.0 ± 0.0
Glu
2.134GluAla: 2.134 ± 1.599
0.0GluCys: 0.0 ± 0.0
3.202GluAsp: 3.202 ± 1.738
3.202GluGlu: 3.202 ± 1.202
1.067GluPhe: 1.067 ± 1.232
2.134GluGly: 2.134 ± 1.93
0.0GluHis: 0.0 ± 0.0
8.538GluIle: 8.538 ± 3.178
7.471GluLys: 7.471 ± 3.872
2.134GluLeu: 2.134 ± 1.19
0.0GluMet: 0.0 ± 0.0
3.202GluAsn: 3.202 ± 1.61
3.202GluPro: 3.202 ± 1.947
3.202GluGln: 3.202 ± 1.755
0.0GluArg: 0.0 ± 0.0
2.134GluSer: 2.134 ± 0.964
3.202GluThr: 3.202 ± 1.591
3.202GluVal: 3.202 ± 2.399
1.067GluTrp: 1.067 ± 1.232
3.202GluTyr: 3.202 ± 1.021
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
5.336PheAsp: 5.336 ± 2.436
3.202PheGlu: 3.202 ± 1.738
2.134PhePhe: 2.134 ± 0.964
3.202PheGly: 3.202 ± 1.795
0.0PheHis: 0.0 ± 0.0
1.067PheIle: 1.067 ± 1.4
2.134PheLys: 2.134 ± 1.599
4.269PheLeu: 4.269 ± 2.247
1.067PheMet: 1.067 ± 0.784
2.134PheAsn: 2.134 ± 2.8
2.134PhePro: 2.134 ± 1.479
3.202PheGln: 3.202 ± 2.545
2.134PheArg: 2.134 ± 1.383
6.403PheSer: 6.403 ± 1.483
3.202PheThr: 3.202 ± 1.755
3.202PheVal: 3.202 ± 1.524
1.067PheTrp: 1.067 ± 1.232
3.202PheTyr: 3.202 ± 1.755
0.0PheXaa: 0.0 ± 0.0
Gly
4.269GlyAla: 4.269 ± 1.655
0.0GlyCys: 0.0 ± 0.0
4.269GlyAsp: 4.269 ± 2.144
2.134GlyGlu: 2.134 ± 0.964
0.0GlyPhe: 0.0 ± 0.0
2.134GlyGly: 2.134 ± 1.041
0.0GlyHis: 0.0 ± 0.0
2.134GlyIle: 2.134 ± 1.914
4.269GlyLys: 4.269 ± 3.198
1.067GlyLeu: 1.067 ± 0.8
1.067GlyMet: 1.067 ± 0.8
0.0GlyAsn: 0.0 ± 0.0
2.134GlyPro: 2.134 ± 1.339
2.134GlyGln: 2.134 ± 1.914
1.067GlyArg: 1.067 ± 0.965
4.269GlySer: 4.269 ± 1.771
7.471GlyThr: 7.471 ± 2.663
1.067GlyVal: 1.067 ± 0.8
0.0GlyTrp: 0.0 ± 0.0
3.202GlyTyr: 3.202 ± 1.591
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
2.134HisHis: 2.134 ± 1.19
2.134HisIle: 2.134 ± 1.36
2.134HisLys: 2.134 ± 1.19
2.134HisLeu: 2.134 ± 1.19
0.0HisMet: 0.0 ± 0.0
1.067HisAsn: 1.067 ± 0.8
1.067HisPro: 1.067 ± 1.4
0.0HisGln: 0.0 ± 0.0
1.067HisArg: 1.067 ± 0.965
1.067HisSer: 1.067 ± 1.232
1.067HisThr: 1.067 ± 0.8
0.0HisVal: 0.0 ± 0.0
1.067HisTrp: 1.067 ± 0.8
1.067HisTyr: 1.067 ± 1.4
0.0HisXaa: 0.0 ± 0.0
Ile
2.134IleAla: 2.134 ± 1.041
1.067IleCys: 1.067 ± 0.957
5.336IleAsp: 5.336 ± 2.436
5.336IleGlu: 5.336 ± 2.188
2.134IlePhe: 2.134 ± 1.36
3.202IleGly: 3.202 ± 1.429
0.0IleHis: 0.0 ± 0.0
3.202IleIle: 3.202 ± 1.61
5.336IleLys: 5.336 ± 3.998
8.538IleLeu: 8.538 ± 2.414
1.067IleMet: 1.067 ± 0.957
5.336IleAsn: 5.336 ± 2.976
5.336IlePro: 5.336 ± 3.844
3.202IleGln: 3.202 ± 1.833
2.134IleArg: 2.134 ± 1.619
6.403IleSer: 6.403 ± 2.705
7.471IleThr: 7.471 ± 3.331
5.336IleVal: 5.336 ± 2.602
1.067IleTrp: 1.067 ± 0.8
3.202IleTyr: 3.202 ± 2.172
0.0IleXaa: 0.0 ± 0.0
Lys
4.269LysAla: 4.269 ± 1.771
0.0LysCys: 0.0 ± 0.0
3.202LysAsp: 3.202 ± 2.172
6.403LysGlu: 6.403 ± 1.606
7.471LysPhe: 7.471 ± 2.491
2.134LysGly: 2.134 ± 1.599
0.0LysHis: 0.0 ± 0.0
1.067LysIle: 1.067 ± 0.957
3.202LysLys: 3.202 ± 1.157
4.269LysLeu: 4.269 ± 1.797
0.0LysMet: 0.0 ± 0.0
5.336LysAsn: 5.336 ± 3.043
1.067LysPro: 1.067 ± 1.232
1.067LysGln: 1.067 ± 0.8
3.202LysArg: 3.202 ± 1.61
1.067LysSer: 1.067 ± 0.8
8.538LysThr: 8.538 ± 4.201
4.269LysVal: 4.269 ± 2.293
3.202LysTrp: 3.202 ± 1.61
5.336LysTyr: 5.336 ± 2.567
0.0LysXaa: 0.0 ± 0.0
Leu
3.202LeuAla: 3.202 ± 1.057
0.0LeuCys: 0.0 ± 0.0
3.202LeuAsp: 3.202 ± 1.485
4.269LeuGlu: 4.269 ± 2.38
3.202LeuPhe: 3.202 ± 2.894
1.067LeuGly: 1.067 ± 0.8
1.067LeuHis: 1.067 ± 0.8
6.403LeuIle: 6.403 ± 1.291
6.403LeuLys: 6.403 ± 1.544
7.471LeuLeu: 7.471 ± 3.043
2.134LeuMet: 2.134 ± 1.041
8.538LeuAsn: 8.538 ± 3.192
5.336LeuPro: 5.336 ± 4.163
2.134LeuGln: 2.134 ± 1.599
2.134LeuArg: 2.134 ± 1.93
4.269LeuSer: 4.269 ± 3.86
3.202LeuThr: 3.202 ± 1.755
6.403LeuVal: 6.403 ± 3.182
3.202LeuTrp: 3.202 ± 1.61
5.336LeuTyr: 5.336 ± 1.992
0.0LeuXaa: 0.0 ± 0.0
Met
2.134MetAla: 2.134 ± 1.041
1.067MetCys: 1.067 ± 1.232
1.067MetAsp: 1.067 ± 1.232
1.067MetGlu: 1.067 ± 0.8
3.202MetPhe: 3.202 ± 1.591
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.134MetLys: 2.134 ± 1.19
2.134MetLeu: 2.134 ± 1.36
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.067MetGln: 1.067 ± 0.8
0.0MetArg: 0.0 ± 0.0
2.134MetSer: 2.134 ± 1.261
0.0MetThr: 0.0 ± 0.0
1.067MetVal: 1.067 ± 0.8
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.134AsnAla: 2.134 ± 1.261
0.0AsnCys: 0.0 ± 0.0
6.403AsnAsp: 6.403 ± 3.472
5.336AsnGlu: 5.336 ± 1.557
5.336AsnPhe: 5.336 ± 2.794
2.134AsnGly: 2.134 ± 0.964
1.067AsnHis: 1.067 ± 1.4
6.403AsnIle: 6.403 ± 1.525
3.202AsnLys: 3.202 ± 1.202
5.336AsnLeu: 5.336 ± 2.847
2.134AsnMet: 2.134 ± 0.896
5.336AsnAsn: 5.336 ± 2.655
6.403AsnPro: 6.403 ± 1.774
3.202AsnGln: 3.202 ± 1.157
2.134AsnArg: 2.134 ± 0.964
6.403AsnSer: 6.403 ± 1.811
3.202AsnThr: 3.202 ± 1.755
2.134AsnVal: 2.134 ± 1.619
1.067AsnTrp: 1.067 ± 0.8
6.403AsnTyr: 6.403 ± 2.823
0.0AsnXaa: 0.0 ± 0.0
Pro
5.336ProAla: 5.336 ± 1.656
1.067ProCys: 1.067 ± 1.232
2.134ProAsp: 2.134 ± 2.8
2.134ProGlu: 2.134 ± 1.36
0.0ProPhe: 0.0 ± 0.0
2.134ProGly: 2.134 ± 1.599
1.067ProHis: 1.067 ± 1.4
2.134ProIle: 2.134 ± 1.339
1.067ProLys: 1.067 ± 0.965
3.202ProLeu: 3.202 ± 2.262
1.067ProMet: 1.067 ± 1.638
6.403ProAsn: 6.403 ± 1.544
6.403ProPro: 6.403 ± 5.128
1.067ProGln: 1.067 ± 0.957
2.134ProArg: 2.134 ± 0.964
4.269ProSer: 4.269 ± 2.253
3.202ProThr: 3.202 ± 1.755
3.202ProVal: 3.202 ± 1.021
0.0ProTrp: 0.0 ± 0.0
1.067ProTyr: 1.067 ± 0.965
0.0ProXaa: 0.0 ± 0.0
Gln
1.067GlnAla: 1.067 ± 0.957
0.0GlnCys: 0.0 ± 0.0
2.134GlnAsp: 2.134 ± 1.261
1.067GlnGlu: 1.067 ± 0.8
1.067GlnPhe: 1.067 ± 0.965
4.269GlnGly: 4.269 ± 2.733
0.0GlnHis: 0.0 ± 0.0
2.134GlnIle: 2.134 ± 1.041
0.0GlnLys: 0.0 ± 0.0
4.269GlnLeu: 4.269 ± 1.655
1.067GlnMet: 1.067 ± 0.8
5.336GlnAsn: 5.336 ± 1.083
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
0.0GlnSer: 0.0 ± 0.0
3.202GlnThr: 3.202 ± 2.031
1.067GlnVal: 1.067 ± 1.232
1.067GlnTrp: 1.067 ± 0.8
2.134GlnTyr: 2.134 ± 1.479
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
1.067ArgGlu: 1.067 ± 0.8
3.202ArgPhe: 3.202 ± 1.202
3.202ArgGly: 3.202 ± 1.057
1.067ArgHis: 1.067 ± 0.8
2.134ArgIle: 2.134 ± 1.93
3.202ArgLys: 3.202 ± 1.833
2.134ArgLeu: 2.134 ± 1.041
0.0ArgMet: 0.0 ± 0.0
6.403ArgAsn: 6.403 ± 1.09
1.067ArgPro: 1.067 ± 0.957
0.0ArgGln: 0.0 ± 0.0
5.336ArgArg: 5.336 ± 3.964
2.134ArgSer: 2.134 ± 1.911
2.134ArgThr: 2.134 ± 1.261
4.269ArgVal: 4.269 ± 2.654
1.067ArgTrp: 1.067 ± 0.8
1.067ArgTyr: 1.067 ± 0.965
0.0ArgXaa: 0.0 ± 0.0
Ser
3.202SerAla: 3.202 ± 2.031
2.134SerCys: 2.134 ± 1.911
6.403SerAsp: 6.403 ± 0.675
1.067SerGlu: 1.067 ± 0.8
3.202SerPhe: 3.202 ± 1.524
6.403SerGly: 6.403 ± 2.113
1.067SerHis: 1.067 ± 0.8
8.538SerIle: 8.538 ± 2.341
1.067SerLys: 1.067 ± 0.8
10.672SerLeu: 10.672 ± 3.471
1.067SerMet: 1.067 ± 0.8
9.605SerAsn: 9.605 ± 3.501
1.067SerPro: 1.067 ± 0.965
1.067SerGln: 1.067 ± 0.957
3.202SerArg: 3.202 ± 2.031
5.336SerSer: 5.336 ± 2.185
6.403SerThr: 6.403 ± 3.129
2.134SerVal: 2.134 ± 1.339
2.134SerTrp: 2.134 ± 1.599
2.134SerTyr: 2.134 ± 1.339
0.0SerXaa: 0.0 ± 0.0
Thr
4.269ThrAla: 4.269 ± 2.522
0.0ThrCys: 0.0 ± 0.0
2.134ThrAsp: 2.134 ± 1.383
4.269ThrGlu: 4.269 ± 1.928
4.269ThrPhe: 4.269 ± 2.522
4.269ThrGly: 4.269 ± 2.182
0.0ThrHis: 0.0 ± 0.0
5.336ThrIle: 5.336 ± 2.239
3.202ThrLys: 3.202 ± 2.399
7.471ThrLeu: 7.471 ± 4.407
3.202ThrMet: 3.202 ± 1.551
2.134ThrAsn: 2.134 ± 1.36
4.269ThrPro: 4.269 ± 1.448
5.336ThrGln: 5.336 ± 1.331
3.202ThrArg: 3.202 ± 1.833
8.538ThrSer: 8.538 ± 3.471
6.403ThrThr: 6.403 ± 1.774
4.269ThrVal: 4.269 ± 2.522
2.134ThrTrp: 2.134 ± 1.599
3.202ThrTyr: 3.202 ± 1.524
0.0ThrXaa: 0.0 ± 0.0
Val
2.134ValAla: 2.134 ± 1.36
0.0ValCys: 0.0 ± 0.0
3.202ValAsp: 3.202 ± 2.642
2.134ValGlu: 2.134 ± 1.599
3.202ValPhe: 3.202 ± 1.485
0.0ValGly: 0.0 ± 0.0
1.067ValHis: 1.067 ± 0.965
5.336ValIle: 5.336 ± 1.083
6.403ValLys: 6.403 ± 1.859
2.134ValLeu: 2.134 ± 1.041
0.0ValMet: 0.0 ± 0.0
1.067ValAsn: 1.067 ± 0.8
3.202ValPro: 3.202 ± 2.02
1.067ValGln: 1.067 ± 0.8
1.067ValArg: 1.067 ± 1.4
2.134ValSer: 2.134 ± 0.964
8.538ValThr: 8.538 ± 4.567
1.067ValVal: 1.067 ± 0.965
1.067ValTrp: 1.067 ± 0.8
3.202ValTyr: 3.202 ± 2.02
0.0ValXaa: 0.0 ± 0.0
Trp
2.134TrpAla: 2.134 ± 1.19
3.202TrpCys: 3.202 ± 1.61
1.067TrpAsp: 1.067 ± 0.8
0.0TrpGlu: 0.0 ± 0.0
1.067TrpPhe: 1.067 ± 0.8
1.067TrpGly: 1.067 ± 0.8
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.134TrpLys: 2.134 ± 1.19
1.067TrpLeu: 1.067 ± 0.8
1.067TrpMet: 1.067 ± 1.232
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.067TrpArg: 1.067 ± 0.8
4.269TrpSer: 4.269 ± 3.198
0.0TrpThr: 0.0 ± 0.0
1.067TrpVal: 1.067 ± 0.8
1.067TrpTrp: 1.067 ± 0.8
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.269TyrAla: 4.269 ± 2.082
1.067TyrCys: 1.067 ± 0.8
5.336TyrAsp: 5.336 ± 2.335
2.134TyrGlu: 2.134 ± 1.261
2.134TyrPhe: 2.134 ± 1.36
1.067TyrGly: 1.067 ± 0.957
1.067TyrHis: 1.067 ± 0.8
6.403TyrIle: 6.403 ± 2.705
3.202TyrLys: 3.202 ± 1.591
6.403TyrLeu: 6.403 ± 2.063
1.067TyrMet: 1.067 ± 0.8
2.134TyrAsn: 2.134 ± 1.339
2.134TyrPro: 2.134 ± 1.599
0.0TyrGln: 0.0 ± 0.0
2.134TyrArg: 2.134 ± 0.964
6.403TyrSer: 6.403 ± 1.294
5.336TyrThr: 5.336 ± 2.069
2.134TyrVal: 2.134 ± 1.619
0.0TyrTrp: 0.0 ± 0.0
6.403TyrTyr: 6.403 ± 4.036
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (938 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski