Amino acid dipepetide frequency for Magnaporthe grisea (Crabgrass-specific blast fungus) (Pyricularia grisea)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.305AlaAla: 11.305 ± 0.072	1.118AlaCys: 1.118 ± 0.016	4.72AlaAsp: 4.72 ± 0.034	5.371AlaGlu: 5.371 ± 0.039	2.98AlaPhe: 2.98 ± 0.028	6.671AlaGly: 6.671 ± 0.043	1.825AlaHis: 1.825 ± 0.018	4.084AlaIle: 4.084 ± 0.032	4.196AlaLys: 4.196 ± 0.038	7.676AlaLeu: 7.676 ± 0.043	2.132AlaMet: 2.132 ± 0.021	3.054AlaAsn: 3.054 ± 0.025	5.253AlaPro: 5.253 ± 0.048	3.554AlaGln: 3.554 ± 0.036	5.431AlaArg: 5.431 ± 0.034	7.675AlaSer: 7.675 ± 0.049	5.897AlaThr: 5.897 ± 0.041	6.059AlaVal: 6.059 ± 0.042	1.185AlaTrp: 1.185 ± 0.016	2.025AlaTyr: 2.025 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.977CysAla: 0.977 ± 0.014	0.272CysCys: 0.272 ± 0.008	0.682CysAsp: 0.682 ± 0.011	0.588CysGlu: 0.588 ± 0.01	0.524CysPhe: 0.524 ± 0.011	1.019CysGly: 1.019 ± 0.018	0.336CysHis: 0.336 ± 0.008	0.684CysIle: 0.684 ± 0.013	0.527CysLys: 0.527 ± 0.01	1.208CysLeu: 1.208 ± 0.017	0.285CysMet: 0.285 ± 0.006	0.455CysAsn: 0.455 ± 0.01	0.676CysPro: 0.676 ± 0.013	0.474CysGln: 0.474 ± 0.009	0.811CysArg: 0.811 ± 0.013	0.952CysSer: 0.952 ± 0.016	0.696CysThr: 0.696 ± 0.012	0.815CysVal: 0.815 ± 0.014	0.206CysTrp: 0.206 ± 0.007	0.333CysTyr: 0.333 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.034AspAla: 5.034 ± 0.032	0.67AspCys: 0.67 ± 0.013	4.668AspAsp: 4.668 ± 0.055	4.419AspGlu: 4.419 ± 0.035	2.128AspPhe: 2.128 ± 0.021	4.629AspGly: 4.629 ± 0.036	1.227AspHis: 1.227 ± 0.016	2.625AspIle: 2.625 ± 0.023	2.568AspLys: 2.568 ± 0.026	4.919AspLeu: 4.919 ± 0.033	1.382AspMet: 1.382 ± 0.018	1.876AspAsn: 1.876 ± 0.019	3.254AspPro: 3.254 ± 0.027	1.941AspGln: 1.941 ± 0.02	3.21AspArg: 3.21 ± 0.034	4.14AspSer: 4.14 ± 0.027	2.716AspThr: 2.716 ± 0.024	3.82AspVal: 3.82 ± 0.026	0.885AspTrp: 0.885 ± 0.013	1.497AspTyr: 1.497 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.599GluAla: 5.599 ± 0.042	0.611GluCys: 0.611 ± 0.011	4.121GluAsp: 4.121 ± 0.035	4.882GluGlu: 4.882 ± 0.051	1.813GluPhe: 1.813 ± 0.018	3.611GluGly: 3.611 ± 0.029	1.291GluHis: 1.291 ± 0.015	2.691GluIle: 2.691 ± 0.023	3.41GluLys: 3.41 ± 0.035	5.024GluLeu: 5.024 ± 0.038	1.477GluMet: 1.477 ± 0.016	2.106GluAsn: 2.106 ± 0.021	2.869GluPro: 2.869 ± 0.033	2.414GluGln: 2.414 ± 0.025	3.796GluArg: 3.796 ± 0.033	3.922GluSer: 3.922 ± 0.028	3.327GluThr: 3.327 ± 0.028	3.561GluVal: 3.561 ± 0.025	0.831GluTrp: 0.831 ± 0.012	1.503GluTyr: 1.503 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.082PheAla: 3.082 ± 0.023	0.554PheCys: 0.554 ± 0.01	2.182PheAsp: 2.182 ± 0.023	1.98PheGlu: 1.98 ± 0.019	1.522PhePhe: 1.522 ± 0.021	2.849PheGly: 2.849 ± 0.032	0.801PheHis: 0.801 ± 0.012	1.594PheIle: 1.594 ± 0.022	1.447PheLys: 1.447 ± 0.016	3.141PheLeu: 3.141 ± 0.025	0.77PheMet: 0.77 ± 0.011	1.347PheAsn: 1.347 ± 0.017	1.854PhePro: 1.854 ± 0.021	1.245PheGln: 1.245 ± 0.015	1.938PheArg: 1.938 ± 0.022	2.815PheSer: 2.815 ± 0.022	1.997PheThr: 1.997 ± 0.019	2.42PheVal: 2.42 ± 0.022	0.603PheTrp: 0.603 ± 0.01	0.994PheTyr: 0.994 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.11GlyAla: 6.11 ± 0.042	0.935GlyCys: 0.935 ± 0.015	4.021GlyAsp: 4.021 ± 0.027	3.643GlyGlu: 3.643 ± 0.028	2.789GlyPhe: 2.789 ± 0.029	7.183GlyGly: 7.183 ± 0.076	1.727GlyHis: 1.727 ± 0.021	3.355GlyIle: 3.355 ± 0.03	3.481GlyLys: 3.481 ± 0.032	6.187GlyLeu: 6.187 ± 0.048	1.695GlyMet: 1.695 ± 0.02	2.726GlyAsn: 2.726 ± 0.025	3.687GlyPro: 3.687 ± 0.033	2.734GlyGln: 2.734 ± 0.024	4.607GlyArg: 4.607 ± 0.032	6.365GlySer: 6.365 ± 0.047	4.213GlyThr: 4.213 ± 0.033	4.593GlyVal: 4.593 ± 0.039	1.143GlyTrp: 1.143 ± 0.014	2.03GlyTyr: 2.03 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.812HisAla: 1.812 ± 0.019	0.327HisCys: 0.327 ± 0.009	1.308HisAsp: 1.308 ± 0.017	1.222HisGlu: 1.222 ± 0.015	0.847HisPhe: 0.847 ± 0.011	1.782HisGly: 1.782 ± 0.02	0.937HisHis: 0.937 ± 0.018	1.092HisIle: 1.092 ± 0.014	0.923HisLys: 0.923 ± 0.013	2.103HisLeu: 2.103 ± 0.02	0.522HisMet: 0.522 ± 0.011	0.833HisAsn: 0.833 ± 0.011	1.549HisPro: 1.549 ± 0.017	1.064HisGln: 1.064 ± 0.018	1.57HisArg: 1.57 ± 0.019	1.731HisSer: 1.731 ± 0.021	1.179HisThr: 1.179 ± 0.015	1.468HisVal: 1.468 ± 0.017	0.32HisTrp: 0.32 ± 0.007	0.664HisTyr: 0.664 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.868IleAla: 3.868 ± 0.032	0.697IleCys: 0.697 ± 0.012	2.589IleAsp: 2.589 ± 0.024	2.561IleGlu: 2.561 ± 0.023	1.774IlePhe: 1.774 ± 0.019	2.996IleGly: 2.996 ± 0.026	1.028IleHis: 1.028 ± 0.014	2.244IleIle: 2.244 ± 0.024	2.157IleLys: 2.157 ± 0.021	4.084IleLeu: 4.084 ± 0.039	1.042IleMet: 1.042 ± 0.016	1.731IleAsn: 1.731 ± 0.023	2.86IlePro: 2.86 ± 0.026	1.647IleGln: 1.647 ± 0.018	2.613IleArg: 2.613 ± 0.025	3.527IleSer: 3.527 ± 0.027	2.676IleThr: 2.676 ± 0.023	3.003IleVal: 3.003 ± 0.028	0.667IleTrp: 0.667 ± 0.01	1.257IleTyr: 1.257 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.329LysAla: 4.329 ± 0.033	0.504LysCys: 0.504 ± 0.01	2.737LysAsp: 2.737 ± 0.029	3.124LysGlu: 3.124 ± 0.033	1.404LysPhe: 1.404 ± 0.019	2.985LysGly: 2.985 ± 0.028	1.066LysHis: 1.066 ± 0.015	2.132LysIle: 2.132 ± 0.021	3.374LysLys: 3.374 ± 0.055	3.961LysLeu: 3.961 ± 0.033	1.052LysMet: 1.052 ± 0.014	1.674LysAsn: 1.674 ± 0.02	2.872LysPro: 2.872 ± 0.032	1.862LysGln: 1.862 ± 0.022	3.256LysArg: 3.256 ± 0.028	3.448LysSer: 3.448 ± 0.029	2.906LysThr: 2.906 ± 0.026	2.791LysVal: 2.791 ± 0.022	0.627LysTrp: 0.627 ± 0.011	1.246LysTyr: 1.246 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.24LeuAla: 8.24 ± 0.051	1.187LeuCys: 1.187 ± 0.016	5.06LeuAsp: 5.06 ± 0.029	5.258LeuGlu: 5.258 ± 0.04	3.064LeuPhe: 3.064 ± 0.031	6.112LeuGly: 6.112 ± 0.042	2.054LeuHis: 2.054 ± 0.021	3.509LeuIle: 3.509 ± 0.032	3.89LeuLys: 3.89 ± 0.031	8.009LeuLeu: 8.009 ± 0.06	1.789LeuMet: 1.789 ± 0.017	2.898LeuAsn: 2.898 ± 0.025	5.44LeuPro: 5.44 ± 0.048	3.561LeuGln: 3.561 ± 0.026	5.72LeuArg: 5.72 ± 0.035	6.803LeuSer: 6.803 ± 0.044	4.543LeuThr: 4.543 ± 0.034	5.58LeuVal: 5.58 ± 0.039	1.152LeuTrp: 1.152 ± 0.017	2.084LeuTyr: 2.084 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.445MetAla: 2.445 ± 0.024	0.254MetCys: 0.254 ± 0.007	1.304MetAsp: 1.304 ± 0.016	1.269MetGlu: 1.269 ± 0.016	0.751MetPhe: 0.751 ± 0.012	1.576MetGly: 1.576 ± 0.02	0.512MetHis: 0.512 ± 0.01	0.94MetIle: 0.94 ± 0.014	0.931MetLys: 0.931 ± 0.013	1.948MetLeu: 1.948 ± 0.024	0.616MetMet: 0.616 ± 0.009	0.763MetAsn: 0.763 ± 0.012	1.402MetPro: 1.402 ± 0.018	0.928MetGln: 0.928 ± 0.013	1.408MetArg: 1.408 ± 0.017	1.938MetSer: 1.938 ± 0.02	1.354MetThr: 1.354 ± 0.018	1.419MetVal: 1.419 ± 0.018	0.27MetTrp: 0.27 ± 0.007	0.529MetTyr: 0.529 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.991AsnAla: 2.991 ± 0.025	0.462AsnCys: 0.462 ± 0.009	1.922AsnAsp: 1.922 ± 0.018	1.816AsnGlu: 1.816 ± 0.015	1.318AsnPhe: 1.318 ± 0.015	3.097AsnGly: 3.097 ± 0.033	0.849AsnHis: 0.849 ± 0.012	1.862AsnIle: 1.862 ± 0.017	1.651AsnLys: 1.651 ± 0.017	3.064AsnLeu: 3.064 ± 0.024	0.91AsnMet: 0.91 ± 0.013	1.707AsnAsn: 1.707 ± 0.027	2.44AsnPro: 2.44 ± 0.024	1.317AsnGln: 1.317 ± 0.016	1.932AsnArg: 1.932 ± 0.019	2.838AsnSer: 2.838 ± 0.027	2.083AsnThr: 2.083 ± 0.02	2.225AsnVal: 2.225 ± 0.017	0.537AsnTrp: 0.537 ± 0.01	0.983AsnTyr: 0.983 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.957ProAla: 5.957 ± 0.045	0.532ProCys: 0.532 ± 0.012	3.268ProAsp: 3.268 ± 0.023	3.792ProGlu: 3.792 ± 0.031	1.92ProPhe: 1.92 ± 0.019	4.456ProGly: 4.456 ± 0.042	1.308ProHis: 1.308 ± 0.018	2.458ProIle: 2.458 ± 0.025	2.729ProLys: 2.729 ± 0.029	4.663ProLeu: 4.663 ± 0.029	1.175ProMet: 1.175 ± 0.016	2.172ProAsn: 2.172 ± 0.02	5.552ProPro: 5.552 ± 0.078	2.584ProGln: 2.584 ± 0.034	3.667ProArg: 3.667 ± 0.032	5.905ProSer: 5.905 ± 0.054	4.191ProThr: 4.191 ± 0.039	3.768ProVal: 3.768 ± 0.032	0.757ProTrp: 0.757 ± 0.014	1.399ProTyr: 1.399 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.6GlnAla: 3.6 ± 0.032	0.442GlnCys: 0.442 ± 0.011	2.102GlnAsp: 2.102 ± 0.02	2.24GlnGlu: 2.24 ± 0.022	1.183GlnPhe: 1.183 ± 0.015	2.549GlnGly: 2.549 ± 0.021	1.123GlnHis: 1.123 ± 0.015	1.721GlnIle: 1.721 ± 0.016	1.883GlnLys: 1.883 ± 0.02	3.406GlnLeu: 3.406 ± 0.025	0.903GlnMet: 0.903 ± 0.013	1.509GlnAsn: 1.509 ± 0.017	2.796GlnPro: 2.796 ± 0.038	3.185GlnGln: 3.185 ± 0.063	2.694GlnArg: 2.694 ± 0.024	3.042GlnSer: 3.042 ± 0.029	2.369GlnThr: 2.369 ± 0.026	2.249GlnVal: 2.249 ± 0.023	0.549GlnTrp: 0.549 ± 0.01	1.049GlnTyr: 1.049 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.037ArgAla: 5.037 ± 0.033	0.785ArgCys: 0.785 ± 0.014	3.657ArgAsp: 3.657 ± 0.038	3.705ArgGlu: 3.705 ± 0.034	2.14ArgPhe: 2.14 ± 0.02	4.059ArgGly: 4.059 ± 0.032	1.653ArgHis: 1.653 ± 0.017	2.802ArgIle: 2.802 ± 0.022	3.287ArgLys: 3.287 ± 0.029	5.579ArgLeu: 5.579 ± 0.041	1.405ArgMet: 1.405 ± 0.016	2.248ArgAsn: 2.248 ± 0.021	3.842ArgPro: 3.842 ± 0.032	2.826ArgGln: 2.826 ± 0.027	5.554ArgArg: 5.554 ± 0.047	4.946ArgSer: 4.946 ± 0.042	3.343ArgThr: 3.343 ± 0.026	3.479ArgVal: 3.479 ± 0.025	0.938ArgTrp: 0.938 ± 0.014	1.592ArgTyr: 1.592 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.986SerAla: 6.986 ± 0.047	0.916SerCys: 0.916 ± 0.013	4.115SerAsp: 4.115 ± 0.031	3.918SerGlu: 3.918 ± 0.03	2.867SerPhe: 2.867 ± 0.021	6.05SerGly: 6.05 ± 0.046	1.855SerHis: 1.855 ± 0.019	3.667SerIle: 3.667 ± 0.029	3.606SerLys: 3.606 ± 0.029	6.82SerLeu: 6.82 ± 0.045	1.777SerMet: 1.777 ± 0.018	2.99SerAsn: 2.99 ± 0.026	5.728SerPro: 5.728 ± 0.058	3.256SerGln: 3.256 ± 0.035	5.259SerArg: 5.259 ± 0.045	9.261SerSer: 9.261 ± 0.089	5.598SerThr: 5.598 ± 0.049	4.606SerVal: 4.606 ± 0.031	1.097SerTrp: 1.097 ± 0.014	1.877SerTyr: 1.877 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.753ThrAla: 5.753 ± 0.039	0.786ThrCys: 0.786 ± 0.013	2.788ThrAsp: 2.788 ± 0.025	2.993ThrGlu: 2.993 ± 0.023	2.081ThrPhe: 2.081 ± 0.021	4.406ThrGly: 4.406 ± 0.044	1.205ThrHis: 1.205 ± 0.014	2.891ThrIle: 2.891 ± 0.025	2.636ThrLys: 2.636 ± 0.026	4.891ThrLeu: 4.891 ± 0.034	1.263ThrMet: 1.263 ± 0.016	2.101ThrAsn: 2.101 ± 0.021	4.399ThrPro: 4.399 ± 0.038	2.09ThrGln: 2.09 ± 0.021	3.237ThrArg: 3.237 ± 0.027	5.412ThrSer: 5.412 ± 0.048	4.745ThrThr: 4.745 ± 0.057	3.871ThrVal: 3.871 ± 0.033	0.805ThrTrp: 0.805 ± 0.012	1.488ThrTyr: 1.488 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.943ValAla: 5.943 ± 0.033	0.86ValCys: 0.86 ± 0.013	3.901ValAsp: 3.901 ± 0.03	3.885ValGlu: 3.885 ± 0.027	2.425ValPhe: 2.425 ± 0.025	4.3ValGly: 4.3 ± 0.039	1.389ValHis: 1.389 ± 0.017	2.744ValIle: 2.744 ± 0.027	2.904ValLys: 2.904 ± 0.023	5.619ValLeu: 5.619 ± 0.041	1.408ValMet: 1.408 ± 0.019	2.182ValAsn: 2.182 ± 0.02	3.762ValPro: 3.762 ± 0.034	2.336ValGln: 2.336 ± 0.022	3.629ValArg: 3.629 ± 0.023	4.637ValSer: 4.637 ± 0.033	3.679ValThr: 3.679 ± 0.035	4.771ValVal: 4.771 ± 0.042	0.853ValTrp: 0.853 ± 0.015	1.668ValTyr: 1.668 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.176TrpAla: 1.176 ± 0.016	0.203TrpCys: 0.203 ± 0.007	0.898TrpAsp: 0.898 ± 0.014	0.809TrpGlu: 0.809 ± 0.011	0.515TrpPhe: 0.515 ± 0.01	0.91TrpGly: 0.91 ± 0.015	0.356TrpHis: 0.356 ± 0.008	0.695TrpIle: 0.695 ± 0.014	0.7TrpLys: 0.7 ± 0.01	1.309TrpLeu: 1.309 ± 0.018	0.351TrpMet: 0.351 ± 0.008	0.57TrpAsn: 0.57 ± 0.01	0.651TrpPro: 0.651 ± 0.01	0.567TrpGln: 0.567 ± 0.01	0.975TrpArg: 0.975 ± 0.014	0.996TrpSer: 0.996 ± 0.015	0.891TrpThr: 0.891 ± 0.014	0.876TrpVal: 0.876 ± 0.014	0.274TrpTrp: 0.274 ± 0.007	0.4TrpTyr: 0.4 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.972TyrAla: 1.972 ± 0.022	0.407TyrCys: 0.407 ± 0.01	1.566TyrAsp: 1.566 ± 0.017	1.385TyrGlu: 1.385 ± 0.018	1.088TyrPhe: 1.088 ± 0.015	1.985TyrGly: 1.985 ± 0.02	0.709TyrHis: 0.709 ± 0.012	1.23TyrIle: 1.23 ± 0.015	1.05TyrLys: 1.05 ± 0.014	2.343TyrLeu: 2.343 ± 0.022	0.601TyrMet: 0.601 ± 0.011	1.064TyrAsn: 1.064 ± 0.015	1.366TyrPro: 1.366 ± 0.021	1.007TyrGln: 1.007 ± 0.015	1.571TyrArg: 1.571 ± 0.017	1.895TyrSer: 1.895 ± 0.019	1.436TyrThr: 1.436 ± 0.021	1.52TyrVal: 1.52 ± 0.015	0.424TyrTrp: 0.424 ± 0.009	0.849TyrTyr: 0.849 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.004

Statistics based on 12455 proteins (5706119 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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