Amino acid dipepetide frequency for Rhizopogon vinicolor AM-OR11-026

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.43AlaAla: 7.43 ± 0.055	1.232AlaCys: 1.232 ± 0.018	3.863AlaAsp: 3.863 ± 0.031	4.373AlaGlu: 4.373 ± 0.035	3.249AlaPhe: 3.249 ± 0.029	4.952AlaGly: 4.952 ± 0.035	2.052AlaHis: 2.052 ± 0.023	4.274AlaIle: 4.274 ± 0.033	3.473AlaLys: 3.473 ± 0.032	8.217AlaLeu: 8.217 ± 0.051	1.895AlaMet: 1.895 ± 0.021	2.581AlaAsn: 2.581 ± 0.021	4.639AlaPro: 4.639 ± 0.038	3.215AlaGln: 3.215 ± 0.026	4.925AlaArg: 4.925 ± 0.038	7.264AlaSer: 7.264 ± 0.04	4.881AlaThr: 4.881 ± 0.034	5.377AlaVal: 5.377 ± 0.033	1.133AlaTrp: 1.133 ± 0.016	2.103AlaTyr: 2.103 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	1.071CysAla: 1.071 ± 0.016	0.327CysCys: 0.327 ± 0.008	0.742CysAsp: 0.742 ± 0.014	0.66CysGlu: 0.66 ± 0.012	0.632CysPhe: 0.632 ± 0.012	1.013CysGly: 1.013 ± 0.015	0.41CysHis: 0.41 ± 0.01	0.946CysIle: 0.946 ± 0.016	0.556CysLys: 0.556 ± 0.012	1.426CysLeu: 1.426 ± 0.019	0.355CysMet: 0.355 ± 0.008	0.503CysAsn: 0.503 ± 0.01	0.871CysPro: 0.871 ± 0.019	0.502CysGln: 0.502 ± 0.011	0.853CysArg: 0.853 ± 0.015	1.189CysSer: 1.189 ± 0.018	0.843CysThr: 0.843 ± 0.016	0.902CysVal: 0.902 ± 0.015	0.237CysTrp: 0.237 ± 0.007	0.379CysTyr: 0.379 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.638AspAla: 4.638 ± 0.035	0.67AspCys: 0.67 ± 0.011	4.095AspAsp: 4.095 ± 0.036	4.156AspGlu: 4.156 ± 0.039	2.054AspPhe: 2.054 ± 0.021	3.897AspGly: 3.897 ± 0.036	1.314AspHis: 1.314 ± 0.016	3.37AspIle: 3.37 ± 0.027	2.143AspLys: 2.143 ± 0.021	4.908AspLeu: 4.908 ± 0.034	1.257AspMet: 1.257 ± 0.015	1.799AspAsn: 1.799 ± 0.017	3.137AspPro: 3.137 ± 0.026	1.618AspGln: 1.618 ± 0.018	2.894AspArg: 2.894 ± 0.028	4.01AspSer: 4.01 ± 0.03	3.091AspThr: 3.091 ± 0.023	4.064AspVal: 4.064 ± 0.034	0.905AspTrp: 0.905 ± 0.018	1.426AspTyr: 1.426 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	4.541GluAla: 4.541 ± 0.035	0.735GluCys: 0.735 ± 0.012	3.907GluAsp: 3.907 ± 0.037	4.778GluGlu: 4.778 ± 0.053	1.891GluPhe: 1.891 ± 0.018	3.48GluGly: 3.48 ± 0.026	1.458GluHis: 1.458 ± 0.016	2.82GluIle: 2.82 ± 0.025	2.942GluLys: 2.942 ± 0.03	5.193GluLeu: 5.193 ± 0.038	1.337GluMet: 1.337 ± 0.017	1.899GluAsn: 1.899 ± 0.017	2.454GluPro: 2.454 ± 0.026	2.119GluGln: 2.119 ± 0.022	3.839GluArg: 3.839 ± 0.034	4.006GluSer: 4.006 ± 0.032	2.995GluThr: 2.995 ± 0.025	3.651GluVal: 3.651 ± 0.032	0.876GluTrp: 0.876 ± 0.015	1.515GluTyr: 1.515 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.112PheAla: 3.112 ± 0.029	0.612PheCys: 0.612 ± 0.012	2.222PheAsp: 2.222 ± 0.023	1.995PheGlu: 1.995 ± 0.021	1.632PhePhe: 1.632 ± 0.021	2.731PheGly: 2.731 ± 0.031	1.0PheHis: 1.0 ± 0.013	2.098PheIle: 2.098 ± 0.024	1.492PheLys: 1.492 ± 0.019	3.666PheLeu: 3.666 ± 0.031	0.881PheMet: 0.881 ± 0.013	1.401PheAsn: 1.401 ± 0.015	2.109PhePro: 2.109 ± 0.021	1.29PheGln: 1.29 ± 0.017	2.003PheArg: 2.003 ± 0.018	3.375PheSer: 3.375 ± 0.025	2.313PheThr: 2.313 ± 0.023	2.58PheVal: 2.58 ± 0.023	0.598PheTrp: 0.598 ± 0.012	1.116PheTyr: 1.116 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.595GlyAla: 4.595 ± 0.035	0.93GlyCys: 0.93 ± 0.015	3.282GlyAsp: 3.282 ± 0.027	3.355GlyGlu: 3.355 ± 0.028	2.459GlyPhe: 2.459 ± 0.025	4.841GlyGly: 4.841 ± 0.044	1.822GlyHis: 1.822 ± 0.021	3.392GlyIle: 3.392 ± 0.031	3.284GlyLys: 3.284 ± 0.025	5.487GlyLeu: 5.487 ± 0.035	1.516GlyMet: 1.516 ± 0.022	2.139GlyAsn: 2.139 ± 0.022	2.981GlyPro: 2.981 ± 0.027	2.215GlyGln: 2.215 ± 0.023	3.845GlyArg: 3.845 ± 0.031	5.342GlySer: 5.342 ± 0.042	3.85GlyThr: 3.85 ± 0.032	4.237GlyVal: 4.237 ± 0.033	1.027GlyTrp: 1.027 ± 0.014	1.897GlyTyr: 1.897 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	2.177HisAla: 2.177 ± 0.025	0.431HisCys: 0.431 ± 0.009	1.499HisAsp: 1.499 ± 0.018	1.335HisGlu: 1.335 ± 0.016	1.034HisPhe: 1.034 ± 0.015	1.653HisGly: 1.653 ± 0.021	0.96HisHis: 0.96 ± 0.016	1.509HisIle: 1.509 ± 0.018	0.961HisLys: 0.961 ± 0.014	2.647HisLeu: 2.647 ± 0.026	0.527HisMet: 0.527 ± 0.01	0.872HisAsn: 0.872 ± 0.013	2.017HisPro: 2.017 ± 0.021	0.961HisGln: 0.961 ± 0.013	1.698HisArg: 1.698 ± 0.021	2.423HisSer: 2.423 ± 0.027	1.638HisThr: 1.638 ± 0.019	1.739HisVal: 1.739 ± 0.017	0.396HisTrp: 0.396 ± 0.009	0.733HisTyr: 0.733 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.482IleAla: 4.482 ± 0.03	0.881IleCys: 0.881 ± 0.013	2.954IleAsp: 2.954 ± 0.026	2.695IleGlu: 2.695 ± 0.022	2.178IlePhe: 2.178 ± 0.022	3.076IleGly: 3.076 ± 0.032	1.387IleHis: 1.387 ± 0.016	2.897IleIle: 2.897 ± 0.031	2.071IleLys: 2.071 ± 0.02	5.021IleLeu: 5.021 ± 0.037	1.148IleMet: 1.148 ± 0.012	1.777IleAsn: 1.777 ± 0.022	3.433IlePro: 3.433 ± 0.024	1.922IleGln: 1.922 ± 0.021	2.998IleArg: 2.998 ± 0.022	4.516IleSer: 4.516 ± 0.033	3.121IleThr: 3.121 ± 0.027	3.532IleVal: 3.532 ± 0.031	0.851IleTrp: 0.851 ± 0.016	1.471IleTyr: 1.471 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	3.684LysAla: 3.684 ± 0.033	0.564LysCys: 0.564 ± 0.013	2.465LysAsp: 2.465 ± 0.026	2.92LysGlu: 2.92 ± 0.031	1.443LysPhe: 1.443 ± 0.016	2.646LysGly: 2.646 ± 0.024	1.186LysHis: 1.186 ± 0.015	2.089LysIle: 2.089 ± 0.02	2.783LysLys: 2.783 ± 0.029	3.961LysLeu: 3.961 ± 0.033	0.956LysMet: 0.956 ± 0.014	1.471LysAsn: 1.471 ± 0.018	2.337LysPro: 2.337 ± 0.028	1.644LysGln: 1.644 ± 0.018	3.221LysArg: 3.221 ± 0.026	3.262LysSer: 3.262 ± 0.028	2.456LysThr: 2.456 ± 0.021	2.708LysVal: 2.708 ± 0.024	0.655LysTrp: 0.655 ± 0.011	1.26LysTyr: 1.26 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.968LeuAla: 7.968 ± 0.044	1.454LeuCys: 1.454 ± 0.021	5.203LeuAsp: 5.203 ± 0.029	5.243LeuGlu: 5.243 ± 0.037	3.534LeuPhe: 3.534 ± 0.032	5.395LeuGly: 5.395 ± 0.035	2.689LeuHis: 2.689 ± 0.03	4.362LeuIle: 4.362 ± 0.035	3.989LeuLys: 3.989 ± 0.029	9.074LeuLeu: 9.074 ± 0.062	1.921LeuMet: 1.921 ± 0.023	3.165LeuAsn: 3.165 ± 0.028	6.273LeuPro: 6.273 ± 0.039	3.953LeuGln: 3.953 ± 0.034	6.026LeuArg: 6.026 ± 0.039	8.508LeuSer: 8.508 ± 0.044	5.436LeuThr: 5.436 ± 0.033	5.858LeuVal: 5.858 ± 0.035	1.348LeuTrp: 1.348 ± 0.018	2.426LeuTyr: 2.426 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.79MetAla: 1.79 ± 0.018	0.321MetCys: 0.321 ± 0.009	1.263MetAsp: 1.263 ± 0.018	1.192MetGlu: 1.192 ± 0.015	0.839MetPhe: 0.839 ± 0.012	1.298MetGly: 1.298 ± 0.018	0.625MetHis: 0.625 ± 0.011	1.119MetIle: 1.119 ± 0.014	1.055MetLys: 1.055 ± 0.014	2.013MetLeu: 2.013 ± 0.021	0.594MetMet: 0.594 ± 0.011	0.84MetAsn: 0.84 ± 0.015	1.246MetPro: 1.246 ± 0.016	0.924MetGln: 0.924 ± 0.013	1.386MetArg: 1.386 ± 0.017	2.167MetSer: 2.167 ± 0.022	1.431MetThr: 1.431 ± 0.015	1.335MetVal: 1.335 ± 0.017	0.294MetTrp: 0.294 ± 0.007	0.582MetTyr: 0.582 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.979AsnAla: 2.979 ± 0.026	0.457AsnCys: 0.457 ± 0.01	1.842AsnAsp: 1.842 ± 0.018	1.734AsnGlu: 1.734 ± 0.017	1.343AsnPhe: 1.343 ± 0.018	2.454AsnGly: 2.454 ± 0.027	0.88AsnHis: 0.88 ± 0.014	2.098AsnIle: 2.098 ± 0.02	1.321AsnLys: 1.321 ± 0.016	3.164AsnLeu: 3.164 ± 0.029	0.804AsnMet: 0.804 ± 0.014	1.261AsnAsn: 1.261 ± 0.018	2.22AsnPro: 2.22 ± 0.023	1.156AsnGln: 1.156 ± 0.015	1.688AsnArg: 1.688 ± 0.018	2.699AsnSer: 2.699 ± 0.022	2.104AsnThr: 2.104 ± 0.023	2.446AsnVal: 2.446 ± 0.022	0.481AsnTrp: 0.481 ± 0.01	0.959AsnTyr: 0.959 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.728ProAla: 4.728 ± 0.044	0.638ProCys: 0.638 ± 0.013	3.2ProAsp: 3.2 ± 0.025	3.391ProGlu: 3.391 ± 0.031	2.202ProPhe: 2.202 ± 0.024	3.476ProGly: 3.476 ± 0.033	1.714ProHis: 1.714 ± 0.021	2.8ProIle: 2.8 ± 0.024	2.318ProLys: 2.318 ± 0.02	5.401ProLeu: 5.401 ± 0.041	1.103ProMet: 1.103 ± 0.016	2.097ProAsn: 2.097 ± 0.022	5.891ProPro: 5.891 ± 0.067	2.406ProGln: 2.406 ± 0.024	3.451ProArg: 3.451 ± 0.03	7.212ProSer: 7.212 ± 0.064	4.169ProThr: 4.169 ± 0.037	3.826ProVal: 3.826 ± 0.031	0.762ProTrp: 0.762 ± 0.013	1.605ProTyr: 1.605 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.075GlnAla: 3.075 ± 0.029	0.535GlnCys: 0.535 ± 0.012	1.969GlnAsp: 1.969 ± 0.022	2.186GlnGlu: 2.186 ± 0.025	1.235GlnPhe: 1.235 ± 0.017	2.167GlnGly: 2.167 ± 0.025	1.1GlnHis: 1.1 ± 0.016	1.856GlnIle: 1.856 ± 0.02	1.618GlnLys: 1.618 ± 0.018	3.486GlnLeu: 3.486 ± 0.03	0.85GlnMet: 0.85 ± 0.013	1.329GlnAsn: 1.329 ± 0.018	2.426GlnPro: 2.426 ± 0.029	1.862GlnGln: 1.862 ± 0.028	2.529GlnArg: 2.529 ± 0.023	3.183GlnSer: 3.183 ± 0.027	2.204GlnThr: 2.204 ± 0.026	2.247GlnVal: 2.247 ± 0.02	0.574GlnTrp: 0.574 ± 0.012	1.105GlnTyr: 1.105 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.832ArgAla: 4.832 ± 0.036	0.876ArgCys: 0.876 ± 0.015	3.238ArgAsp: 3.238 ± 0.027	3.652ArgGlu: 3.652 ± 0.032	2.216ArgPhe: 2.216 ± 0.022	3.515ArgGly: 3.515 ± 0.034	1.68ArgHis: 1.68 ± 0.022	3.104ArgIle: 3.104 ± 0.029	3.225ArgLys: 3.225 ± 0.03	5.635ArgLeu: 5.635 ± 0.035	1.432ArgMet: 1.432 ± 0.018	2.021ArgAsn: 2.021 ± 0.019	3.522ArgPro: 3.522 ± 0.027	2.352ArgGln: 2.352 ± 0.025	4.953ArgArg: 4.953 ± 0.043	5.113ArgSer: 5.113 ± 0.042	3.511ArgThr: 3.511 ± 0.032	3.747ArgVal: 3.747 ± 0.029	1.044ArgTrp: 1.044 ± 0.016	1.675ArgTyr: 1.675 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.849SerAla: 6.849 ± 0.042	1.188SerCys: 1.188 ± 0.018	4.585SerAsp: 4.585 ± 0.033	4.075SerGlu: 4.075 ± 0.026	3.452SerPhe: 3.452 ± 0.028	5.538SerGly: 5.538 ± 0.039	2.41SerHis: 2.41 ± 0.024	4.436SerIle: 4.436 ± 0.036	3.424SerLys: 3.424 ± 0.029	8.304SerLeu: 8.304 ± 0.046	1.955SerMet: 1.955 ± 0.019	2.968SerAsn: 2.968 ± 0.028	6.375SerPro: 6.375 ± 0.059	3.261SerGln: 3.261 ± 0.03	5.397SerArg: 5.397 ± 0.046	10.363SerSer: 10.363 ± 0.081	6.154SerThr: 6.154 ± 0.047	5.25SerVal: 5.25 ± 0.033	1.158SerTrp: 1.158 ± 0.016	2.272SerTyr: 2.272 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.776ThrAla: 4.776 ± 0.03	0.934ThrCys: 0.934 ± 0.015	2.735ThrAsp: 2.735 ± 0.022	2.787ThrGlu: 2.787 ± 0.023	2.501ThrPhe: 2.501 ± 0.024	3.844ThrGly: 3.844 ± 0.028	1.583ThrHis: 1.583 ± 0.02	3.347ThrIle: 3.347 ± 0.024	2.366ThrLys: 2.366 ± 0.024	5.886ThrLeu: 5.886 ± 0.038	1.284ThrMet: 1.284 ± 0.015	2.018ThrAsn: 2.018 ± 0.019	4.425ThrPro: 4.425 ± 0.037	2.12ThrGln: 2.12 ± 0.026	3.369ThrArg: 3.369 ± 0.027	6.132ThrSer: 6.132 ± 0.045	4.245ThrThr: 4.245 ± 0.035	3.88ThrVal: 3.88 ± 0.03	0.854ThrTrp: 0.854 ± 0.015	1.642ThrTyr: 1.642 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	5.184ValAla: 5.184 ± 0.032	0.937ValCys: 0.937 ± 0.014	3.722ValAsp: 3.722 ± 0.029	3.716ValGlu: 3.716 ± 0.027	2.575ValPhe: 2.575 ± 0.026	3.846ValGly: 3.846 ± 0.03	1.755ValHis: 1.755 ± 0.017	3.566ValIle: 3.566 ± 0.028	2.87ValLys: 2.87 ± 0.029	6.29ValLeu: 6.29 ± 0.042	1.493ValMet: 1.493 ± 0.015	2.233ValAsn: 2.233 ± 0.019	3.893ValPro: 3.893 ± 0.026	2.458ValGln: 2.458 ± 0.021	3.716ValArg: 3.716 ± 0.028	5.193ValSer: 5.193 ± 0.036	3.728ValThr: 3.728 ± 0.027	4.726ValVal: 4.726 ± 0.037	1.022ValTrp: 1.022 ± 0.015	1.765ValTyr: 1.765 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.076TrpAla: 1.076 ± 0.014	0.239TrpCys: 0.239 ± 0.007	1.003TrpAsp: 1.003 ± 0.019	0.803TrpGlu: 0.803 ± 0.013	0.557TrpPhe: 0.557 ± 0.01	0.853TrpGly: 0.853 ± 0.013	0.375TrpHis: 0.375 ± 0.008	0.787TrpIle: 0.787 ± 0.013	0.798TrpLys: 0.798 ± 0.013	1.406TrpLeu: 1.406 ± 0.029	0.406TrpMet: 0.406 ± 0.01	0.68TrpAsn: 0.68 ± 0.014	0.575TrpPro: 0.575 ± 0.011	0.556TrpGln: 0.556 ± 0.012	1.003TrpArg: 1.003 ± 0.014	1.251TrpSer: 1.251 ± 0.016	0.939TrpThr: 0.939 ± 0.015	0.901TrpVal: 0.901 ± 0.014	0.304TrpTrp: 0.304 ± 0.008	0.409TrpTyr: 0.409 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.141TyrAla: 2.141 ± 0.023	0.461TyrCys: 0.461 ± 0.011	1.658TyrAsp: 1.658 ± 0.02	1.388TyrGlu: 1.388 ± 0.018	1.201TyrPhe: 1.201 ± 0.016	1.82TyrGly: 1.82 ± 0.021	0.81TyrHis: 0.81 ± 0.013	1.541TyrIle: 1.541 ± 0.02	1.024TyrLys: 1.024 ± 0.015	2.64TyrLeu: 2.64 ± 0.024	0.6TyrMet: 0.6 ± 0.009	1.036TyrAsn: 1.036 ± 0.015	1.567TyrPro: 1.567 ± 0.021	1.001TyrGln: 1.001 ± 0.017	1.549TyrArg: 1.549 ± 0.019	2.204TyrSer: 2.204 ± 0.023	1.62TyrThr: 1.62 ± 0.019	1.68TyrVal: 1.68 ± 0.018	0.399TyrTrp: 0.399 ± 0.008	0.892TyrTyr: 0.892 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.039XaaXaa: 0.039 ± 0.029

Statistics based on 14447 proteins (5225860 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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