Amino acid dipepetide frequency for Desulfuromonas soudanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.402AlaAla: 12.402 ± 0.154	1.244AlaCys: 1.244 ± 0.041	4.99AlaAsp: 4.99 ± 0.073	6.991AlaGlu: 6.991 ± 0.1	3.772AlaPhe: 3.772 ± 0.066	9.404AlaGly: 9.404 ± 0.127	1.699AlaHis: 1.699 ± 0.04	5.161AlaIle: 5.161 ± 0.075	3.131AlaLys: 3.131 ± 0.066	12.619AlaLeu: 12.619 ± 0.157	2.387AlaMet: 2.387 ± 0.05	2.323AlaAsn: 2.323 ± 0.062	4.45AlaPro: 4.45 ± 0.083	2.661AlaGln: 2.661 ± 0.052	6.789AlaArg: 6.789 ± 0.095	4.878AlaSer: 4.878 ± 0.077	4.802AlaThr: 4.802 ± 0.094	7.728AlaVal: 7.728 ± 0.077	1.018AlaTrp: 1.018 ± 0.033	2.219AlaTyr: 2.219 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.155CysAla: 1.155 ± 0.036	0.184CysCys: 0.184 ± 0.013	0.599CysAsp: 0.599 ± 0.022	0.527CysGlu: 0.527 ± 0.024	0.397CysPhe: 0.397 ± 0.018	1.317CysGly: 1.317 ± 0.045	0.675CysHis: 0.675 ± 0.086	0.505CysIle: 0.505 ± 0.024	0.329CysLys: 0.329 ± 0.017	1.08CysLeu: 1.08 ± 0.028	0.199CysMet: 0.199 ± 0.014	0.317CysAsn: 0.317 ± 0.019	0.735CysPro: 0.735 ± 0.032	0.379CysGln: 0.379 ± 0.018	0.985CysArg: 0.985 ± 0.033	0.721CysSer: 0.721 ± 0.03	0.549CysThr: 0.549 ± 0.024	0.552CysVal: 0.552 ± 0.023	0.112CysTrp: 0.112 ± 0.012	0.31CysTyr: 0.31 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.532AspAla: 4.532 ± 0.074	0.631AspCys: 0.631 ± 0.035	2.635AspAsp: 2.635 ± 0.053	3.33AspGlu: 3.33 ± 0.047	2.59AspPhe: 2.59 ± 0.049	4.586AspGly: 4.586 ± 0.092	0.983AspHis: 0.983 ± 0.03	2.974AspIle: 2.974 ± 0.057	1.822AspLys: 1.822 ± 0.043	6.71AspLeu: 6.71 ± 0.088	0.982AspMet: 0.982 ± 0.025	1.548AspAsn: 1.548 ± 0.061	3.249AspPro: 3.249 ± 0.062	1.512AspGln: 1.512 ± 0.036	3.844AspArg: 3.844 ± 0.057	2.471AspSer: 2.471 ± 0.051	2.237AspThr: 2.237 ± 0.085	3.176AspVal: 3.176 ± 0.055	0.663AspTrp: 0.663 ± 0.024	1.75AspTyr: 1.75 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.765GluAla: 6.765 ± 0.094	0.504GluCys: 0.504 ± 0.021	2.922GluAsp: 2.922 ± 0.051	5.868GluGlu: 5.868 ± 0.098	2.16GluPhe: 2.16 ± 0.05	5.811GluGly: 5.811 ± 0.079	1.156GluHis: 1.156 ± 0.033	4.699GluIle: 4.699 ± 0.07	3.935GluLys: 3.935 ± 0.066	6.76GluLeu: 6.76 ± 0.104	1.791GluMet: 1.791 ± 0.042	2.121GluAsn: 2.121 ± 0.05	2.314GluPro: 2.314 ± 0.053	2.048GluGln: 2.048 ± 0.048	4.809GluArg: 4.809 ± 0.086	3.169GluSer: 3.169 ± 0.059	3.67GluThr: 3.67 ± 0.059	5.064GluVal: 5.064 ± 0.078	0.598GluTrp: 0.598 ± 0.022	1.447GluTyr: 1.447 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	4.16PheAla: 4.16 ± 0.076	0.597PheCys: 0.597 ± 0.022	2.563PheAsp: 2.563 ± 0.049	2.244PheGlu: 2.244 ± 0.041	2.009PhePhe: 2.009 ± 0.044	3.474PheGly: 3.474 ± 0.058	0.813PheHis: 0.813 ± 0.027	1.965PheIle: 1.965 ± 0.046	1.407PheLys: 1.407 ± 0.032	4.618PheLeu: 4.618 ± 0.069	0.805PheMet: 0.805 ± 0.031	1.279PheAsn: 1.279 ± 0.034	1.949PhePro: 1.949 ± 0.045	1.051PheGln: 1.051 ± 0.032	2.416PheArg: 2.416 ± 0.053	2.87PheSer: 2.87 ± 0.05	2.163PheThr: 2.163 ± 0.052	2.725PheVal: 2.725 ± 0.057	0.491PheTrp: 0.491 ± 0.02	1.141PheTyr: 1.141 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	8.009GlyAla: 8.009 ± 0.104	1.215GlyCys: 1.215 ± 0.042	4.555GlyAsp: 4.555 ± 0.085	6.48GlyGlu: 6.48 ± 0.093	3.403GlyPhe: 3.403 ± 0.052	7.446GlyGly: 7.446 ± 0.119	1.725GlyHis: 1.725 ± 0.037	5.216GlyIle: 5.216 ± 0.075	4.021GlyLys: 4.021 ± 0.067	8.505GlyLeu: 8.505 ± 0.098	2.256GlyMet: 2.256 ± 0.049	2.646GlyAsn: 2.646 ± 0.103	2.752GlyPro: 2.752 ± 0.053	2.508GlyGln: 2.508 ± 0.052	5.828GlyArg: 5.828 ± 0.084	4.867GlySer: 4.867 ± 0.084	5.162GlyThr: 5.162 ± 0.103	6.406GlyVal: 6.406 ± 0.084	1.028GlyTrp: 1.028 ± 0.031	2.558GlyTyr: 2.558 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.582HisAla: 1.582 ± 0.04	0.284HisCys: 0.284 ± 0.015	0.997HisAsp: 0.997 ± 0.04	0.943HisGlu: 0.943 ± 0.029	0.987HisPhe: 0.987 ± 0.033	1.757HisGly: 1.757 ± 0.054	0.526HisHis: 0.526 ± 0.022	0.923HisIle: 0.923 ± 0.029	0.638HisLys: 0.638 ± 0.026	2.479HisLeu: 2.479 ± 0.051	0.363HisMet: 0.363 ± 0.019	0.611HisAsn: 0.611 ± 0.028	1.473HisPro: 1.473 ± 0.046	0.694HisGln: 0.694 ± 0.024	1.629HisArg: 1.629 ± 0.036	1.074HisSer: 1.074 ± 0.035	0.826HisThr: 0.826 ± 0.033	1.041HisVal: 1.041 ± 0.034	0.227HisTrp: 0.227 ± 0.014	0.588HisTyr: 0.588 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.419IleAla: 5.419 ± 0.078	0.63IleCys: 0.63 ± 0.025	3.573IleAsp: 3.573 ± 0.06	3.686IleGlu: 3.686 ± 0.066	2.332IlePhe: 2.332 ± 0.045	4.472IleGly: 4.472 ± 0.067	1.213IleHis: 1.213 ± 0.032	2.543IleIle: 2.543 ± 0.059	1.976IleLys: 1.976 ± 0.043	6.327IleLeu: 6.327 ± 0.101	0.921IleMet: 0.921 ± 0.035	1.726IleAsn: 1.726 ± 0.045	3.074IlePro: 3.074 ± 0.059	1.425IleGln: 1.425 ± 0.041	3.522IleArg: 3.522 ± 0.067	3.208IleSer: 3.208 ± 0.064	2.625IleThr: 2.625 ± 0.049	3.78IleVal: 3.78 ± 0.062	0.41IleTrp: 0.41 ± 0.02	1.394IleTyr: 1.394 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	3.631LysAla: 3.631 ± 0.072	0.324LysCys: 0.324 ± 0.019	2.021LysAsp: 2.021 ± 0.044	3.178LysGlu: 3.178 ± 0.063	1.146LysPhe: 1.146 ± 0.032	3.555LysGly: 3.555 ± 0.059	0.644LysHis: 0.644 ± 0.024	2.683LysIle: 2.683 ± 0.058	2.707LysLys: 2.707 ± 0.061	3.462LysLeu: 3.462 ± 0.071	1.037LysMet: 1.037 ± 0.03	1.51LysAsn: 1.51 ± 0.039	1.535LysPro: 1.535 ± 0.038	1.008LysGln: 1.008 ± 0.033	2.447LysArg: 2.447 ± 0.048	2.089LysSer: 2.089 ± 0.045	2.362LysThr: 2.362 ± 0.042	2.979LysVal: 2.979 ± 0.062	0.291LysTrp: 0.291 ± 0.016	0.968LysTyr: 0.968 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	12.562LeuAla: 12.562 ± 0.141	1.345LeuCys: 1.345 ± 0.033	6.078LeuAsp: 6.078 ± 0.082	7.397LeuGlu: 7.397 ± 0.099	4.81LeuPhe: 4.81 ± 0.088	9.321LeuGly: 9.321 ± 0.107	2.216LeuHis: 2.216 ± 0.052	5.373LeuIle: 5.373 ± 0.084	4.563LeuLys: 4.563 ± 0.079	13.501LeuLeu: 13.501 ± 0.191	2.107LeuMet: 2.107 ± 0.045	2.922LeuAsn: 2.922 ± 0.056	6.063LeuPro: 6.063 ± 0.085	3.993LeuGln: 3.993 ± 0.073	7.506LeuArg: 7.506 ± 0.121	6.983LeuSer: 6.983 ± 0.096	6.091LeuThr: 6.091 ± 0.085	7.891LeuVal: 7.891 ± 0.096	1.129LeuTrp: 1.129 ± 0.04	2.713LeuTyr: 2.713 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.56MetAla: 2.56 ± 0.044	0.143MetCys: 0.143 ± 0.01	1.021MetAsp: 1.021 ± 0.032	1.533MetGlu: 1.533 ± 0.034	0.624MetPhe: 0.624 ± 0.027	1.69MetGly: 1.69 ± 0.037	0.314MetHis: 0.314 ± 0.018	1.242MetIle: 1.242 ± 0.035	1.333MetLys: 1.333 ± 0.036	1.924MetLeu: 1.924 ± 0.047	0.495MetMet: 0.495 ± 0.021	0.846MetAsn: 0.846 ± 0.026	0.982MetPro: 0.982 ± 0.029	0.652MetGln: 0.652 ± 0.027	1.185MetArg: 1.185 ± 0.032	1.181MetSer: 1.181 ± 0.032	1.44MetThr: 1.44 ± 0.037	1.743MetVal: 1.743 ± 0.037	0.107MetTrp: 0.107 ± 0.011	0.365MetTyr: 0.365 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.585AsnAla: 2.585 ± 0.065	0.391AsnCys: 0.391 ± 0.024	1.475AsnAsp: 1.475 ± 0.067	1.349AsnGlu: 1.349 ± 0.039	1.25AsnPhe: 1.25 ± 0.033	2.33AsnGly: 2.33 ± 0.074	0.565AsnHis: 0.565 ± 0.024	1.727AsnIle: 1.727 ± 0.04	0.985AsnLys: 0.985 ± 0.036	3.654AsnLeu: 3.654 ± 0.06	0.555AsnMet: 0.555 ± 0.023	0.948AsnAsn: 0.948 ± 0.044	2.025AsnPro: 2.025 ± 0.043	0.858AsnGln: 0.858 ± 0.032	2.07AsnArg: 2.07 ± 0.045	1.438AsnSer: 1.438 ± 0.045	1.316AsnThr: 1.316 ± 0.05	1.907AsnVal: 1.907 ± 0.057	0.356AsnTrp: 0.356 ± 0.02	0.84AsnTyr: 0.84 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	5.127ProAla: 5.127 ± 0.1	0.474ProCys: 0.474 ± 0.02	2.643ProAsp: 2.643 ± 0.049	4.019ProGlu: 4.019 ± 0.065	2.156ProPhe: 2.156 ± 0.04	4.691ProGly: 4.691 ± 0.069	0.921ProHis: 0.921 ± 0.029	1.931ProIle: 1.931 ± 0.05	1.435ProLys: 1.435 ± 0.04	5.857ProLeu: 5.857 ± 0.08	1.06ProMet: 1.06 ± 0.029	1.005ProAsn: 1.005 ± 0.031	2.728ProPro: 2.728 ± 0.064	1.589ProGln: 1.589 ± 0.046	2.791ProArg: 2.791 ± 0.057	2.535ProSer: 2.535 ± 0.054	2.178ProThr: 2.178 ± 0.051	3.973ProVal: 3.973 ± 0.065	0.633ProTrp: 0.633 ± 0.025	1.253ProTyr: 1.253 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.195GlnAla: 3.195 ± 0.055	0.251GlnCys: 0.251 ± 0.014	1.356GlnAsp: 1.356 ± 0.034	2.315GlnGlu: 2.315 ± 0.057	1.021GlnPhe: 1.021 ± 0.033	2.942GlnGly: 2.942 ± 0.044	0.512GlnHis: 0.512 ± 0.023	1.903GlnIle: 1.903 ± 0.039	1.603GlnLys: 1.603 ± 0.045	2.947GlnLeu: 2.947 ± 0.054	0.723GlnMet: 0.723 ± 0.026	0.917GlnAsn: 0.917 ± 0.03	1.136GlnPro: 1.136 ± 0.034	1.207GlnGln: 1.207 ± 0.037	2.111GlnArg: 2.111 ± 0.046	1.56GlnSer: 1.56 ± 0.034	1.682GlnThr: 1.682 ± 0.042	2.499GlnVal: 2.499 ± 0.051	0.349GlnTrp: 0.349 ± 0.018	0.614GlnTyr: 0.614 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	5.389ArgAla: 5.389 ± 0.08	0.751ArgCys: 0.751 ± 0.027	3.399ArgAsp: 3.399 ± 0.052	4.952ArgGlu: 4.952 ± 0.093	2.97ArgPhe: 2.97 ± 0.048	4.888ArgGly: 4.888 ± 0.073	1.518ArgHis: 1.518 ± 0.039	4.378ArgIle: 4.378 ± 0.07	2.7ArgLys: 2.7 ± 0.053	8.135ArgLeu: 8.135 ± 0.107	1.559ArgMet: 1.559 ± 0.037	1.865ArgAsn: 1.865 ± 0.044	3.012ArgPro: 3.012 ± 0.066	2.942ArgGln: 2.942 ± 0.057	5.597ArgArg: 5.597 ± 0.108	3.595ArgSer: 3.595 ± 0.06	3.145ArgThr: 3.145 ± 0.057	4.573ArgVal: 4.573 ± 0.071	0.768ArgTrp: 0.768 ± 0.03	2.01ArgTyr: 2.01 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.557SerAla: 5.557 ± 0.073	0.747SerCys: 0.747 ± 0.034	2.8SerAsp: 2.8 ± 0.058	3.138SerGlu: 3.138 ± 0.057	2.45SerPhe: 2.45 ± 0.044	5.542SerGly: 5.542 ± 0.083	1.113SerHis: 1.113 ± 0.031	2.65SerIle: 2.65 ± 0.054	1.66SerLys: 1.66 ± 0.043	6.525SerLeu: 6.525 ± 0.068	1.071SerMet: 1.071 ± 0.029	1.433SerAsn: 1.433 ± 0.04	3.038SerPro: 3.038 ± 0.064	1.62SerGln: 1.62 ± 0.039	3.939SerArg: 3.939 ± 0.058	3.112SerSer: 3.112 ± 0.069	2.664SerThr: 2.664 ± 0.064	3.561SerVal: 3.561 ± 0.06	0.646SerTrp: 0.646 ± 0.028	1.442SerTyr: 1.442 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.26ThrAla: 5.26 ± 0.101	0.63ThrCys: 0.63 ± 0.036	2.477ThrAsp: 2.477 ± 0.056	2.79ThrGlu: 2.79 ± 0.051	2.24ThrPhe: 2.24 ± 0.051	4.951ThrGly: 4.951 ± 0.109	0.863ThrHis: 0.863 ± 0.034	2.705ThrIle: 2.705 ± 0.056	1.347ThrLys: 1.347 ± 0.039	7.129ThrLeu: 7.129 ± 0.109	0.925ThrMet: 0.925 ± 0.032	1.289ThrAsn: 1.289 ± 0.051	3.183ThrPro: 3.183 ± 0.063	1.111ThrGln: 1.111 ± 0.032	2.859ThrArg: 2.859 ± 0.054	2.707ThrSer: 2.707 ± 0.063	2.744ThrThr: 2.744 ± 0.08	4.47ThrVal: 4.47 ± 0.085	0.506ThrTrp: 0.506 ± 0.024	1.376ThrTyr: 1.376 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	7.787ValAla: 7.787 ± 0.082	0.856ValCys: 0.856 ± 0.031	4.1ValAsp: 4.1 ± 0.063	4.935ValGlu: 4.935 ± 0.077	2.831ValPhe: 2.831 ± 0.053	5.32ValGly: 5.32 ± 0.064	1.346ValHis: 1.346 ± 0.037	4.052ValIle: 4.052 ± 0.068	2.723ValLys: 2.723 ± 0.056	7.84ValLeu: 7.84 ± 0.079	1.477ValMet: 1.477 ± 0.039	2.181ValAsn: 2.181 ± 0.051	3.412ValPro: 3.412 ± 0.067	2.042ValGln: 2.042 ± 0.044	4.78ValArg: 4.78 ± 0.067	4.173ValSer: 4.173 ± 0.066	4.129ValThr: 4.129 ± 0.077	5.76ValVal: 5.76 ± 0.085	0.638ValTrp: 0.638 ± 0.025	1.668ValTyr: 1.668 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.773TrpAla: 0.773 ± 0.028	0.113TrpCys: 0.113 ± 0.01	0.569TrpAsp: 0.569 ± 0.022	0.669TrpGlu: 0.669 ± 0.025	0.415TrpPhe: 0.415 ± 0.018	0.84TrpGly: 0.84 ± 0.03	0.232TrpHis: 0.232 ± 0.015	0.544TrpIle: 0.544 ± 0.025	0.43TrpLys: 0.43 ± 0.023	1.159TrpLeu: 1.159 ± 0.036	0.252TrpMet: 0.252 ± 0.017	0.356TrpAsn: 0.356 ± 0.018	0.483TrpPro: 0.483 ± 0.019	0.529TrpGln: 0.529 ± 0.022	0.749TrpArg: 0.749 ± 0.028	0.637TrpSer: 0.637 ± 0.024	0.526TrpThr: 0.526 ± 0.031	0.697TrpVal: 0.697 ± 0.031	0.158TrpTrp: 0.158 ± 0.012	0.286TrpTyr: 0.286 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.219TyrAla: 2.219 ± 0.046	0.311TyrCys: 0.311 ± 0.017	1.453TyrAsp: 1.453 ± 0.04	1.268TyrGlu: 1.268 ± 0.038	1.179TyrPhe: 1.179 ± 0.038	2.25TyrGly: 2.25 ± 0.046	0.609TyrHis: 0.609 ± 0.022	1.081TyrIle: 1.081 ± 0.035	0.832TyrLys: 0.832 ± 0.03	3.335TyrLeu: 3.335 ± 0.063	0.411TyrMet: 0.411 ± 0.018	0.781TyrAsn: 0.781 ± 0.03	1.405TyrPro: 1.405 ± 0.033	1.013TyrGln: 1.013 ± 0.032	2.294TyrArg: 2.294 ± 0.048	1.439TyrSer: 1.439 ± 0.038	1.251TyrThr: 1.251 ± 0.044	1.526TyrVal: 1.526 ± 0.037	0.285TyrTrp: 0.285 ± 0.017	0.834TyrTyr: 0.834 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3469 proteins (1153148 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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