Amino acid dipepetide frequency for Ludwigia yellow vein virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.715AlaAla: 7.715 ± 3.968
1.929AlaCys: 1.929 ± 1.673
1.929AlaAsp: 1.929 ± 1.158
3.857AlaGlu: 3.857 ± 2.205
1.929AlaPhe: 1.929 ± 1.15
1.929AlaGly: 1.929 ± 1.163
0.964AlaHis: 0.964 ± 1.157
3.857AlaIle: 3.857 ± 1.544
2.893AlaLys: 2.893 ± 1.542
5.786AlaLeu: 5.786 ± 2.711
0.0AlaMet: 0.0 ± 0.0
1.929AlaAsn: 1.929 ± 1.03
3.857AlaPro: 3.857 ± 2.183
4.822AlaGln: 4.822 ± 2.122
3.857AlaArg: 3.857 ± 2.286
1.929AlaSer: 1.929 ± 0.944
4.822AlaThr: 4.822 ± 2.428
0.0AlaVal: 0.0 ± 0.0
1.929AlaTrp: 1.929 ± 0.944
0.964AlaTyr: 0.964 ± 0.836
0.0AlaXaa: 0.0 ± 0.0
Cys
0.964CysAla: 0.964 ± 1.03
1.929CysCys: 1.929 ± 2.315
0.0CysAsp: 0.0 ± 0.0
0.964CysGlu: 0.964 ± 0.836
0.964CysPhe: 0.964 ± 0.975
1.929CysGly: 1.929 ± 1.03
0.0CysHis: 0.0 ± 0.0
1.929CysIle: 1.929 ± 1.146
1.929CysLys: 1.929 ± 1.673
0.964CysLeu: 0.964 ± 1.157
1.929CysMet: 1.929 ± 1.59
1.929CysAsn: 1.929 ± 1.03
3.857CysPro: 3.857 ± 2.326
0.964CysGln: 0.964 ± 0.975
0.0CysArg: 0.0 ± 0.0
0.964CysSer: 0.964 ± 1.03
1.929CysThr: 1.929 ± 1.15
0.964CysVal: 0.964 ± 0.836
0.964CysTrp: 0.964 ± 0.812
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.822AspAla: 4.822 ± 1.953
0.0AspCys: 0.0 ± 0.0
0.964AspAsp: 0.964 ± 0.812
0.964AspGlu: 0.964 ± 0.836
0.964AspPhe: 0.964 ± 0.975
3.857AspGly: 3.857 ± 2.239
0.964AspHis: 0.964 ± 0.975
2.893AspIle: 2.893 ± 1.549
1.929AspLys: 1.929 ± 0.968
7.715AspLeu: 7.715 ± 3.509
0.0AspMet: 0.0 ± 0.0
0.964AspAsn: 0.964 ± 0.836
1.929AspPro: 1.929 ± 1.163
0.964AspGln: 0.964 ± 0.812
2.893AspArg: 2.893 ± 1.588
2.893AspSer: 2.893 ± 1.727
1.929AspThr: 1.929 ± 2.315
7.715AspVal: 7.715 ± 2.0
2.893AspTrp: 2.893 ± 1.542
1.929AspTyr: 1.929 ± 1.03
0.0AspXaa: 0.0 ± 0.0
Glu
5.786GluAla: 5.786 ± 1.679
1.929GluCys: 1.929 ± 1.163
0.964GluAsp: 0.964 ± 1.023
4.822GluGlu: 4.822 ± 2.244
1.929GluPhe: 1.929 ± 1.163
3.857GluGly: 3.857 ± 0.851
0.964GluHis: 0.964 ± 1.157
0.0GluIle: 0.0 ± 0.0
4.822GluLys: 4.822 ± 2.433
2.893GluLeu: 2.893 ± 1.638
0.0GluMet: 0.0 ± 0.0
3.857GluAsn: 3.857 ± 2.356
2.893GluPro: 2.893 ± 1.419
0.964GluGln: 0.964 ± 0.836
0.964GluArg: 0.964 ± 0.975
2.893GluSer: 2.893 ± 1.099
0.964GluThr: 0.964 ± 1.157
1.929GluVal: 1.929 ± 1.133
0.964GluTrp: 0.964 ± 1.03
1.929GluTyr: 1.929 ± 0.968
0.0GluXaa: 0.0 ± 0.0
Phe
0.964PheAla: 0.964 ± 0.812
0.964PheCys: 0.964 ± 0.836
2.893PheAsp: 2.893 ± 1.549
0.964PheGlu: 0.964 ± 0.836
1.929PhePhe: 1.929 ± 1.533
0.964PheGly: 0.964 ± 0.836
1.929PheHis: 1.929 ± 1.623
0.964PheIle: 0.964 ± 0.812
4.822PheLys: 4.822 ± 2.079
5.786PheLeu: 5.786 ± 2.126
0.964PheMet: 0.964 ± 0.812
2.893PheAsn: 2.893 ± 1.501
3.857PhePro: 3.857 ± 3.252
5.786PheGln: 5.786 ± 2.712
2.893PheArg: 2.893 ± 1.368
1.929PheSer: 1.929 ± 1.371
0.964PheThr: 0.964 ± 1.03
0.964PheVal: 0.964 ± 0.812
1.929PheTrp: 1.929 ± 1.673
0.964PheTyr: 0.964 ± 0.836
0.0PheXaa: 0.0 ± 0.0
Gly
1.929GlyAla: 1.929 ± 1.623
1.929GlyCys: 1.929 ± 1.15
1.929GlyAsp: 1.929 ± 1.03
3.857GlyGlu: 3.857 ± 0.851
2.893GlyPhe: 2.893 ± 1.485
2.893GlyGly: 2.893 ± 1.549
2.893GlyHis: 2.893 ± 1.041
3.857GlyIle: 3.857 ± 1.127
4.822GlyLys: 4.822 ± 2.433
0.964GlyLeu: 0.964 ± 0.836
1.929GlyMet: 1.929 ± 1.171
1.929GlyAsn: 1.929 ± 1.158
3.857GlyPro: 3.857 ± 1.714
2.893GlyGln: 2.893 ± 0.924
2.893GlyArg: 2.893 ± 1.099
0.964GlySer: 0.964 ± 0.812
4.822GlyThr: 4.822 ± 1.298
3.857GlyVal: 3.857 ± 1.504
0.0GlyTrp: 0.0 ± 0.0
0.964GlyTyr: 0.964 ± 1.157
0.0GlyXaa: 0.0 ± 0.0
His
1.929HisAla: 1.929 ± 0.944
4.822HisCys: 4.822 ± 2.436
1.929HisAsp: 1.929 ± 1.171
0.964HisGlu: 0.964 ± 1.157
2.893HisPhe: 2.893 ± 1.638
1.929HisGly: 1.929 ± 1.626
0.964HisHis: 0.964 ± 1.03
0.964HisIle: 0.964 ± 0.975
0.0HisLys: 0.0 ± 0.0
2.893HisLeu: 2.893 ± 1.497
0.0HisMet: 0.0 ± 0.0
3.857HisAsn: 3.857 ± 1.716
1.929HisPro: 1.929 ± 1.623
1.929HisGln: 1.929 ± 1.171
3.857HisArg: 3.857 ± 2.299
0.964HisSer: 0.964 ± 0.812
2.893HisThr: 2.893 ± 2.509
2.893HisVal: 2.893 ± 1.501
0.0HisTrp: 0.0 ± 0.0
0.964HisTyr: 0.964 ± 0.812
0.0HisXaa: 0.0 ± 0.0
Ile
0.964IleAla: 0.964 ± 1.03
0.964IleCys: 0.964 ± 0.975
1.929IleAsp: 1.929 ± 0.968
0.964IleGlu: 0.964 ± 0.812
3.857IlePhe: 3.857 ± 3.246
0.0IleGly: 0.0 ± 0.0
0.964IleHis: 0.964 ± 0.812
4.822IleIle: 4.822 ± 2.386
8.679IleLys: 8.679 ± 1.242
2.893IleLeu: 2.893 ± 1.727
1.929IleMet: 1.929 ± 1.017
1.929IleAsn: 1.929 ± 1.171
3.857IlePro: 3.857 ± 1.681
2.893IleGln: 2.893 ± 1.497
6.75IleArg: 6.75 ± 0.996
4.822IleSer: 4.822 ± 2.462
6.75IleThr: 6.75 ± 2.676
2.893IleVal: 2.893 ± 0.941
0.964IleTrp: 0.964 ± 0.975
2.893IleTyr: 2.893 ± 1.588
0.0IleXaa: 0.0 ± 0.0
Lys
4.822LysAla: 4.822 ± 1.97
0.964LysCys: 0.964 ± 0.812
0.964LysAsp: 0.964 ± 0.812
6.75LysGlu: 6.75 ± 2.532
0.964LysPhe: 0.964 ± 0.836
1.929LysGly: 1.929 ± 1.623
3.857LysHis: 3.857 ± 1.314
3.857LysIle: 3.857 ± 1.498
2.893LysLys: 2.893 ± 1.727
3.857LysLeu: 3.857 ± 1.314
0.0LysMet: 0.0 ± 0.0
3.857LysAsn: 3.857 ± 2.356
3.857LysPro: 3.857 ± 1.066
0.0LysGln: 0.0 ± 0.0
3.857LysArg: 3.857 ± 1.846
5.786LysSer: 5.786 ± 1.84
1.929LysThr: 1.929 ± 0.944
4.822LysVal: 4.822 ± 1.964
0.0LysTrp: 0.0 ± 0.0
2.893LysTyr: 2.893 ± 1.368
0.0LysXaa: 0.0 ± 0.0
Leu
1.929LeuAla: 1.929 ± 1.163
2.893LeuCys: 2.893 ± 1.549
5.786LeuAsp: 5.786 ± 2.089
5.786LeuGlu: 5.786 ± 2.215
1.929LeuPhe: 1.929 ± 1.03
4.822LeuGly: 4.822 ± 1.966
3.857LeuHis: 3.857 ± 1.322
5.786LeuIle: 5.786 ± 1.893
2.893LeuLys: 2.893 ± 0.924
1.929LeuLeu: 1.929 ± 1.146
1.929LeuMet: 1.929 ± 2.046
2.893LeuAsn: 2.893 ± 1.549
2.893LeuPro: 2.893 ± 1.893
3.857LeuGln: 3.857 ± 2.402
5.786LeuArg: 5.786 ± 3.318
1.929LeuSer: 1.929 ± 1.623
4.822LeuThr: 4.822 ± 1.48
0.964LeuVal: 0.964 ± 0.836
0.964LeuTrp: 0.964 ± 0.836
5.786LeuTyr: 5.786 ± 3.078
0.0LeuXaa: 0.0 ± 0.0
Met
0.964MetAla: 0.964 ± 0.836
0.0MetCys: 0.0 ± 0.0
1.929MetAsp: 1.929 ± 1.171
0.0MetGlu: 0.0 ± 0.0
0.964MetPhe: 0.964 ± 0.836
1.929MetGly: 1.929 ± 1.133
0.964MetHis: 0.964 ± 0.975
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.964MetLeu: 0.964 ± 1.157
0.964MetMet: 0.964 ± 1.023
0.964MetAsn: 0.964 ± 0.836
1.929MetPro: 1.929 ± 1.133
2.893MetGln: 2.893 ± 1.832
0.0MetArg: 0.0 ± 0.0
1.929MetSer: 1.929 ± 1.146
0.0MetThr: 0.0 ± 0.0
0.964MetVal: 0.964 ± 0.836
1.929MetTrp: 1.929 ± 1.163
1.929MetTyr: 1.929 ± 1.673
0.0MetXaa: 0.0 ± 0.0
Asn
2.893AsnAla: 2.893 ± 1.588
0.0AsnCys: 0.0 ± 0.0
2.893AsnAsp: 2.893 ± 1.549
1.929AsnGlu: 1.929 ± 1.158
1.929AsnPhe: 1.929 ± 0.944
0.964AsnGly: 0.964 ± 0.836
5.786AsnHis: 5.786 ± 3.195
1.929AsnIle: 1.929 ± 0.944
0.0AsnLys: 0.0 ± 0.0
3.857AsnLeu: 3.857 ± 1.935
1.929AsnMet: 1.929 ± 1.594
3.857AsnAsn: 3.857 ± 2.116
5.786AsnPro: 5.786 ± 0.856
0.0AsnGln: 0.0 ± 0.0
0.964AsnArg: 0.964 ± 0.836
5.786AsnSer: 5.786 ± 3.633
3.857AsnThr: 3.857 ± 1.322
3.857AsnVal: 3.857 ± 1.59
0.0AsnTrp: 0.0 ± 0.0
2.893AsnTyr: 2.893 ± 1.368
0.0AsnXaa: 0.0 ± 0.0
Pro
1.929ProAla: 1.929 ± 0.944
2.893ProCys: 2.893 ± 1.485
3.857ProAsp: 3.857 ± 2.278
3.857ProGlu: 3.857 ± 2.183
1.929ProPhe: 1.929 ± 0.968
4.822ProGly: 4.822 ± 1.902
3.857ProHis: 3.857 ± 1.716
4.822ProIle: 4.822 ± 2.221
4.822ProLys: 4.822 ± 3.049
2.893ProLeu: 2.893 ± 1.924
0.0ProMet: 0.0 ± 0.944
2.893ProAsn: 2.893 ± 1.685
1.929ProPro: 1.929 ± 1.133
0.964ProGln: 0.964 ± 0.975
7.715ProArg: 7.715 ± 1.818
3.857ProSer: 3.857 ± 1.836
2.893ProThr: 2.893 ± 1.041
7.715ProVal: 7.715 ± 2.191
0.964ProTrp: 0.964 ± 0.812
0.964ProTyr: 0.964 ± 0.836
0.0ProXaa: 0.0 ± 0.0
Gln
4.822GlnAla: 4.822 ± 2.605
1.929GlnCys: 1.929 ± 1.949
0.964GlnAsp: 0.964 ± 1.03
1.929GlnGlu: 1.929 ± 0.944
4.822GlnPhe: 4.822 ± 2.966
0.964GlnGly: 0.964 ± 0.812
0.964GlnHis: 0.964 ± 1.03
2.893GlnIle: 2.893 ± 1.497
2.893GlnLys: 2.893 ± 1.998
1.929GlnLeu: 1.929 ± 1.371
0.0GlnMet: 0.0 ± 0.0
2.893GlnAsn: 2.893 ± 1.485
0.964GlnPro: 0.964 ± 1.03
2.893GlnGln: 2.893 ± 2.001
0.964GlnArg: 0.964 ± 0.812
3.857GlnSer: 3.857 ± 1.045
3.857GlnThr: 3.857 ± 2.342
5.786GlnVal: 5.786 ± 1.161
0.0GlnTrp: 0.0 ± 0.0
1.929GlnTyr: 1.929 ± 1.171
0.0GlnXaa: 0.0 ± 0.0
Arg
2.893ArgAla: 2.893 ± 1.501
0.964ArgCys: 0.964 ± 1.157
5.786ArgAsp: 5.786 ± 1.226
1.929ArgGlu: 1.929 ± 1.03
3.857ArgPhe: 3.857 ± 1.837
3.857ArgGly: 3.857 ± 1.43
1.929ArgHis: 1.929 ± 1.163
3.857ArgIle: 3.857 ± 1.136
2.893ArgLys: 2.893 ± 1.787
6.75ArgLeu: 6.75 ± 2.448
1.929ArgMet: 1.929 ± 1.088
3.857ArgAsn: 3.857 ± 1.544
7.715ArgPro: 7.715 ± 2.473
0.0ArgGln: 0.0 ± 0.0
9.643ArgArg: 9.643 ± 4.677
3.857ArgSer: 3.857 ± 2.286
6.75ArgThr: 6.75 ± 2.028
2.893ArgVal: 2.893 ± 1.099
0.0ArgTrp: 0.0 ± 0.0
0.964ArgTyr: 0.964 ± 1.157
0.0ArgXaa: 0.0 ± 0.0
Ser
0.964SerAla: 0.964 ± 0.812
0.0SerCys: 0.0 ± 0.0
4.822SerAsp: 4.822 ± 1.967
0.0SerGlu: 0.0 ± 0.0
3.857SerPhe: 3.857 ± 1.305
2.893SerGly: 2.893 ± 1.832
2.893SerHis: 2.893 ± 2.463
5.786SerIle: 5.786 ± 1.17
4.822SerLys: 4.822 ± 2.034
0.964SerLeu: 0.964 ± 0.812
0.964SerMet: 0.964 ± 1.023
4.822SerAsn: 4.822 ± 2.138
7.715SerPro: 7.715 ± 1.642
2.893SerGln: 2.893 ± 1.414
3.857SerArg: 3.857 ± 2.157
9.643SerSer: 9.643 ± 4.442
5.786SerThr: 5.786 ± 2.496
1.929SerVal: 1.929 ± 1.171
0.0SerTrp: 0.0 ± 0.0
1.929SerTyr: 1.929 ± 1.03
0.0SerXaa: 0.0 ± 0.0
Thr
2.893ThrAla: 2.893 ± 0.944
0.964ThrCys: 0.964 ± 1.03
0.964ThrAsp: 0.964 ± 0.812
1.929ThrGlu: 1.929 ± 1.146
0.0ThrPhe: 0.0 ± 0.0
7.715ThrGly: 7.715 ± 2.261
3.857ThrHis: 3.857 ± 1.498
4.822ThrIle: 4.822 ± 1.579
2.893ThrLys: 2.893 ± 0.944
5.786ThrLeu: 5.786 ± 1.88
0.964ThrMet: 0.964 ± 0.812
0.964ThrAsn: 0.964 ± 0.836
3.857ThrPro: 3.857 ± 2.293
1.929ThrGln: 1.929 ± 1.371
4.822ThrArg: 4.822 ± 2.497
4.822ThrSer: 4.822 ± 2.438
0.964ThrThr: 0.964 ± 0.836
6.75ThrVal: 6.75 ± 3.509
0.964ThrTrp: 0.964 ± 0.975
3.857ThrTyr: 3.857 ± 1.348
0.0ThrXaa: 0.0 ± 0.0
Val
1.929ValAla: 1.929 ± 1.163
0.0ValCys: 0.0 ± 0.0
3.857ValAsp: 3.857 ± 2.239
2.893ValGlu: 2.893 ± 2.174
4.822ValPhe: 4.822 ± 1.577
1.929ValGly: 1.929 ± 1.158
0.964ValHis: 0.964 ± 1.03
4.822ValIle: 4.822 ± 1.832
2.893ValLys: 2.893 ± 1.041
4.822ValLeu: 4.822 ± 2.458
1.929ValMet: 1.929 ± 1.673
0.964ValAsn: 0.964 ± 0.975
2.893ValPro: 2.893 ± 0.924
8.679ValGln: 8.679 ± 4.267
4.822ValArg: 4.822 ± 1.334
5.786ValSer: 5.786 ± 1.269
1.929ValThr: 1.929 ± 1.673
1.929ValVal: 1.929 ± 0.944
0.0ValTrp: 0.0 ± 0.0
2.893ValTyr: 2.893 ± 1.787
0.0ValXaa: 0.0 ± 0.0
Trp
2.893TrpAla: 2.893 ± 1.542
0.0TrpCys: 0.0 ± 0.0
0.964TrpAsp: 0.964 ± 1.157
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.964TrpGly: 0.964 ± 0.812
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.964TrpLys: 0.964 ± 0.836
0.964TrpLeu: 0.964 ± 0.836
0.964TrpMet: 0.964 ± 0.836
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.964TrpGln: 0.964 ± 0.812
1.929TrpArg: 1.929 ± 1.03
0.0TrpSer: 0.0 ± 0.0
2.893TrpThr: 2.893 ± 1.986
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.964TrpTyr: 0.964 ± 0.812
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.893TyrAla: 2.893 ± 1.655
0.0TyrCys: 0.0 ± 0.0
3.857TyrAsp: 3.857 ± 1.837
0.964TyrGlu: 0.964 ± 0.836
2.893TyrPhe: 2.893 ± 1.365
1.929TyrGly: 1.929 ± 0.944
0.0TyrHis: 0.0 ± 0.0
3.857TyrIle: 3.857 ± 1.314
0.0TyrLys: 0.0 ± 0.0
4.822TyrLeu: 4.822 ± 1.544
1.929TyrMet: 1.929 ± 1.11
3.857TyrAsn: 3.857 ± 1.67
0.964TyrPro: 0.964 ± 0.812
0.964TyrGln: 0.964 ± 1.03
3.857TyrArg: 3.857 ± 3.346
1.929TyrSer: 1.929 ± 1.163
0.964TyrThr: 0.964 ± 0.975
1.929TyrVal: 1.929 ± 1.163
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1038 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski