Amino acid dipepetide frequency for Apis mellifera associated microvirus 59

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.058AlaAla: 11.058 ± 5.366
0.0AlaCys: 0.0 ± 0.0
4.739AlaAsp: 4.739 ± 2.737
5.529AlaGlu: 5.529 ± 1.55
3.16AlaPhe: 3.16 ± 1.442
5.529AlaGly: 5.529 ± 2.18
2.37AlaHis: 2.37 ± 1.68
2.37AlaIle: 2.37 ± 1.368
2.37AlaLys: 2.37 ± 2.59
7.109AlaLeu: 7.109 ± 2.908
3.16AlaMet: 3.16 ± 1.717
3.16AlaAsn: 3.16 ± 1.974
3.16AlaPro: 3.16 ± 2.24
3.16AlaGln: 3.16 ± 1.416
5.529AlaArg: 5.529 ± 1.675
6.319AlaSer: 6.319 ± 2.102
1.58AlaThr: 1.58 ± 0.653
2.37AlaVal: 2.37 ± 1.273
3.16AlaTrp: 3.16 ± 1.395
2.37AlaTyr: 2.37 ± 1.68
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.58CysAsp: 1.58 ± 0.698
0.79CysGlu: 0.79 ± 0.56
0.0CysPhe: 0.0 ± 0.0
1.58CysGly: 1.58 ± 1.462
0.0CysHis: 0.0 ± 0.0
0.79CysIle: 0.79 ± 0.731
0.0CysLys: 0.0 ± 0.0
0.79CysLeu: 0.79 ± 0.731
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.79CysPro: 0.79 ± 0.731
0.79CysGln: 0.79 ± 0.56
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.79CysVal: 0.79 ± 0.56
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.529AspAla: 5.529 ± 2.518
0.79AspCys: 0.79 ± 0.56
2.37AspAsp: 2.37 ± 1.315
2.37AspGlu: 2.37 ± 2.443
2.37AspPhe: 2.37 ± 0.969
3.949AspGly: 3.949 ± 0.721
1.58AspHis: 1.58 ± 0.653
2.37AspIle: 2.37 ± 0.433
1.58AspLys: 1.58 ± 1.461
7.899AspLeu: 7.899 ± 0.994
2.37AspMet: 2.37 ± 1.036
4.739AspAsn: 4.739 ± 0.849
3.16AspPro: 3.16 ± 2.24
1.58AspGln: 1.58 ± 0.698
4.739AspArg: 4.739 ± 0.867
1.58AspSer: 1.58 ± 0.814
5.529AspThr: 5.529 ± 2.156
1.58AspVal: 1.58 ± 0.698
1.58AspTrp: 1.58 ± 1.12
4.739AspTyr: 4.739 ± 0.849
0.0AspXaa: 0.0 ± 0.0
Glu
3.16GluAla: 3.16 ± 0.973
1.58GluCys: 1.58 ± 0.698
6.319GluAsp: 6.319 ± 1.492
1.58GluGlu: 1.58 ± 1.329
3.949GluPhe: 3.949 ± 1.581
4.739GluGly: 4.739 ± 3.748
0.79GluHis: 0.79 ± 0.56
5.529GluIle: 5.529 ± 0.883
3.949GluLys: 3.949 ± 3.532
2.37GluLeu: 2.37 ± 1.259
0.79GluMet: 0.79 ± 0.735
1.58GluAsn: 1.58 ± 1.471
2.37GluPro: 2.37 ± 2.443
4.739GluGln: 4.739 ± 2.072
4.739GluArg: 4.739 ± 1.751
1.58GluSer: 1.58 ± 0.653
3.16GluThr: 3.16 ± 2.04
0.79GluVal: 0.79 ± 0.56
1.58GluTrp: 1.58 ± 0.698
3.949GluTyr: 3.949 ± 1.671
0.0GluXaa: 0.0 ± 0.0
Phe
3.949PheAla: 3.949 ± 1.058
0.79PheCys: 0.79 ± 0.56
3.949PheAsp: 3.949 ± 2.8
0.79PheGlu: 0.79 ± 0.735
0.0PhePhe: 0.0 ± 0.0
4.739PheGly: 4.739 ± 3.36
0.0PheHis: 0.0 ± 0.0
3.16PheIle: 3.16 ± 1.508
0.79PheLys: 0.79 ± 0.731
0.79PheLeu: 0.79 ± 0.731
2.37PheMet: 2.37 ± 0.928
3.16PheAsn: 3.16 ± 1.228
0.79PhePro: 0.79 ± 0.731
0.79PheGln: 0.79 ± 0.735
3.949PheArg: 3.949 ± 1.462
2.37PheSer: 2.37 ± 1.368
1.58PheThr: 1.58 ± 1.12
0.79PheVal: 0.79 ± 0.56
0.0PheTrp: 0.0 ± 0.0
0.79PheTyr: 0.79 ± 0.56
0.0PheXaa: 0.0 ± 0.0
Gly
5.529GlyAla: 5.529 ± 1.507
0.0GlyCys: 0.0 ± 0.0
6.319GlyAsp: 6.319 ± 1.492
6.319GlyGlu: 6.319 ± 1.186
1.58GlyPhe: 1.58 ± 0.698
7.109GlyGly: 7.109 ± 1.618
0.79GlyHis: 0.79 ± 0.56
4.739GlyIle: 4.739 ± 0.782
3.16GlyLys: 3.16 ± 2.924
5.529GlyLeu: 5.529 ± 2.518
0.79GlyMet: 0.79 ± 1.22
4.739GlyAsn: 4.739 ± 1.939
1.58GlyPro: 1.58 ± 1.12
3.16GlyGln: 3.16 ± 0.583
3.16GlyArg: 3.16 ± 1.691
6.319GlySer: 6.319 ± 2.613
2.37GlyThr: 2.37 ± 1.033
3.16GlyVal: 3.16 ± 1.004
0.79GlyTrp: 0.79 ± 0.731
2.37GlyTyr: 2.37 ± 1.228
0.0GlyXaa: 0.0 ± 0.0
His
0.79HisAla: 0.79 ± 0.731
0.0HisCys: 0.0 ± 0.0
1.58HisAsp: 1.58 ± 1.12
1.58HisGlu: 1.58 ± 1.461
3.16HisPhe: 3.16 ± 1.508
2.37HisGly: 2.37 ± 1.68
0.79HisHis: 0.79 ± 0.731
2.37HisIle: 2.37 ± 1.033
3.16HisLys: 3.16 ± 1.009
0.79HisLeu: 0.79 ± 0.56
0.79HisMet: 0.79 ± 0.591
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.79HisGln: 0.79 ± 0.735
1.58HisArg: 1.58 ± 0.698
0.79HisSer: 0.79 ± 0.731
0.0HisThr: 0.0 ± 0.0
0.79HisVal: 0.79 ± 0.735
0.0HisTrp: 0.0 ± 0.0
1.58HisTyr: 1.58 ± 0.698
0.0HisXaa: 0.0 ± 0.0
Ile
2.37IleAla: 2.37 ± 1.961
0.0IleCys: 0.0 ± 0.0
3.949IleAsp: 3.949 ± 1.23
3.949IleGlu: 3.949 ± 1.211
3.16IlePhe: 3.16 ± 1.442
2.37IleGly: 2.37 ± 1.033
1.58IleHis: 1.58 ± 0.698
3.949IleIle: 3.949 ± 1.671
3.949IleLys: 3.949 ± 1.707
4.739IleLeu: 4.739 ± 1.023
2.37IleMet: 2.37 ± 1.259
2.37IleAsn: 2.37 ± 1.768
3.949IlePro: 3.949 ± 0.721
3.949IleGln: 3.949 ± 1.178
5.529IleArg: 5.529 ± 2.318
3.16IleSer: 3.16 ± 1.508
4.739IleThr: 4.739 ± 2.629
0.79IleVal: 0.79 ± 0.735
0.79IleTrp: 0.79 ± 0.735
2.37IleTyr: 2.37 ± 1.033
0.0IleXaa: 0.0 ± 0.0
Lys
3.16LysAla: 3.16 ± 2.359
0.79LysCys: 0.79 ± 0.731
3.16LysAsp: 3.16 ± 1.628
4.739LysGlu: 4.739 ± 3.748
1.58LysPhe: 1.58 ± 1.12
3.16LysGly: 3.16 ± 1.009
0.79LysHis: 0.79 ± 0.735
5.529LysIle: 5.529 ± 3.149
2.37LysLys: 2.37 ± 1.961
5.529LysLeu: 5.529 ± 0.883
3.949LysMet: 3.949 ± 1.211
2.37LysAsn: 2.37 ± 1.033
3.16LysPro: 3.16 ± 1.228
3.949LysGln: 3.949 ± 3.676
3.16LysArg: 3.16 ± 2.924
3.949LysSer: 3.949 ± 2.779
3.949LysThr: 3.949 ± 1.374
4.739LysVal: 4.739 ± 2.407
0.79LysTrp: 0.79 ± 0.731
1.58LysTyr: 1.58 ± 0.698
0.0LysXaa: 0.0 ± 0.0
Leu
3.949LeuAla: 3.949 ± 1.885
0.0LeuCys: 0.0 ± 0.0
2.37LeuAsp: 2.37 ± 1.768
3.16LeuGlu: 3.16 ± 0.583
3.949LeuPhe: 3.949 ± 1.974
3.949LeuGly: 3.949 ± 1.555
1.58LeuHis: 1.58 ± 0.653
3.16LeuIle: 3.16 ± 1.717
10.269LeuLys: 10.269 ± 3.249
1.58LeuLeu: 1.58 ± 1.329
1.58LeuMet: 1.58 ± 1.462
5.529LeuAsn: 5.529 ± 2.393
6.319LeuPro: 6.319 ± 3.209
3.949LeuGln: 3.949 ± 1.555
5.529LeuArg: 5.529 ± 1.55
5.529LeuSer: 5.529 ± 4.149
3.949LeuThr: 3.949 ± 1.707
4.739LeuVal: 4.739 ± 1.959
0.79LeuTrp: 0.79 ± 0.56
3.16LeuTyr: 3.16 ± 1.442
0.0LeuXaa: 0.0 ± 0.0
Met
4.739MetAla: 4.739 ± 1.917
0.0MetCys: 0.0 ± 0.0
1.58MetAsp: 1.58 ± 1.106
1.58MetGlu: 1.58 ± 2.44
1.58MetPhe: 1.58 ± 1.461
0.79MetGly: 0.79 ± 1.22
1.58MetHis: 1.58 ± 0.698
0.0MetIle: 0.0 ± 0.0
3.949MetLys: 3.949 ± 2.231
3.16MetLeu: 3.16 ± 2.04
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.949MetPro: 3.949 ± 0.899
0.0MetGln: 0.0 ± 0.0
3.16MetArg: 3.16 ± 1.306
3.16MetSer: 3.16 ± 2.01
1.58MetThr: 1.58 ± 1.106
0.79MetVal: 0.79 ± 0.56
0.0MetTrp: 0.0 ± 0.0
1.58MetTyr: 1.58 ± 0.698
0.0MetXaa: 0.0 ± 0.0
Asn
3.16AsnAla: 3.16 ± 1.004
1.58AsnCys: 1.58 ± 1.462
3.949AsnAsp: 3.949 ± 0.833
2.37AsnGlu: 2.37 ± 2.26
1.58AsnPhe: 1.58 ± 0.653
3.949AsnGly: 3.949 ± 0.899
0.79AsnHis: 0.79 ± 0.731
3.16AsnIle: 3.16 ± 0.583
3.949AsnLys: 3.949 ± 1.555
4.739AsnLeu: 4.739 ± 1.76
1.58AsnMet: 1.58 ± 1.12
2.37AsnAsn: 2.37 ± 1.273
2.37AsnPro: 2.37 ± 1.273
2.37AsnGln: 2.37 ± 0.969
3.16AsnArg: 3.16 ± 0.583
3.16AsnSer: 3.16 ± 1.306
3.949AsnThr: 3.949 ± 1.885
3.16AsnVal: 3.16 ± 0.985
0.0AsnTrp: 0.0 ± 0.0
2.37AsnTyr: 2.37 ± 0.433
0.0AsnXaa: 0.0 ± 0.0
Pro
3.949ProAla: 3.949 ± 1.058
0.79ProCys: 0.79 ± 0.731
1.58ProAsp: 1.58 ± 1.106
2.37ProGlu: 2.37 ± 1.259
1.58ProPhe: 1.58 ± 0.698
3.16ProGly: 3.16 ± 1.004
0.79ProHis: 0.79 ± 0.731
4.739ProIle: 4.739 ± 2.136
2.37ProLys: 2.37 ± 1.036
3.16ProLeu: 3.16 ± 1.442
2.37ProMet: 2.37 ± 1.033
3.16ProAsn: 3.16 ± 0.583
0.79ProPro: 0.79 ± 0.56
4.739ProGln: 4.739 ± 0.849
3.949ProArg: 3.949 ± 0.721
5.529ProSer: 5.529 ± 2.135
0.79ProThr: 0.79 ± 1.22
4.739ProVal: 4.739 ± 1.959
1.58ProTrp: 1.58 ± 1.12
0.79ProTyr: 0.79 ± 0.56
0.0ProXaa: 0.0 ± 0.0
Gln
2.37GlnAla: 2.37 ± 1.273
0.0GlnCys: 0.0 ± 0.0
1.58GlnAsp: 1.58 ± 1.12
7.899GlnGlu: 7.899 ± 2.24
0.79GlnPhe: 0.79 ± 0.56
3.16GlnGly: 3.16 ± 1.306
0.79GlnHis: 0.79 ± 0.731
2.37GlnIle: 2.37 ± 1.259
3.16GlnLys: 3.16 ± 1.974
4.739GlnLeu: 4.739 ± 2.844
2.37GlnMet: 2.37 ± 2.478
4.739GlnAsn: 4.739 ± 0.867
0.79GlnPro: 0.79 ± 0.731
3.16GlnGln: 3.16 ± 1.442
4.739GlnArg: 4.739 ± 0.867
2.37GlnSer: 2.37 ± 0.969
0.79GlnThr: 0.79 ± 0.56
0.79GlnVal: 0.79 ± 0.56
0.79GlnTrp: 0.79 ± 0.56
1.58GlnTyr: 1.58 ± 1.461
0.0GlnXaa: 0.0 ± 0.0
Arg
4.739ArgAla: 4.739 ± 2.498
0.0ArgCys: 0.0 ± 0.0
3.949ArgAsp: 3.949 ± 1.683
4.739ArgGlu: 4.739 ± 2.667
1.58ArgPhe: 1.58 ± 1.12
1.58ArgGly: 1.58 ± 1.106
0.79ArgHis: 0.79 ± 0.56
3.949ArgIle: 3.949 ± 1.555
4.739ArgLys: 4.739 ± 2.723
7.109ArgLeu: 7.109 ± 1.3
2.37ArgMet: 2.37 ± 1.315
5.529ArgAsn: 5.529 ± 1.658
4.739ArgPro: 4.739 ± 1.023
1.58ArgGln: 1.58 ± 0.698
5.529ArgArg: 5.529 ± 0.861
3.949ArgSer: 3.949 ± 1.959
2.37ArgThr: 2.37 ± 1.036
4.739ArgVal: 4.739 ± 1.664
0.0ArgTrp: 0.0 ± 0.0
3.949ArgTyr: 3.949 ± 1.581
0.0ArgXaa: 0.0 ± 0.0
Ser
7.899SerAla: 7.899 ± 4.509
0.0SerCys: 0.0 ± 0.0
1.58SerAsp: 1.58 ± 1.106
3.16SerGlu: 3.16 ± 2.01
0.79SerPhe: 0.79 ± 0.56
5.529SerGly: 5.529 ± 1.978
2.37SerHis: 2.37 ± 1.228
4.739SerIle: 4.739 ± 1.959
6.319SerLys: 6.319 ± 2.156
4.739SerLeu: 4.739 ± 2.065
1.58SerMet: 1.58 ± 1.329
3.16SerAsn: 3.16 ± 1.974
3.16SerPro: 3.16 ± 1.416
3.16SerGln: 3.16 ± 0.973
2.37SerArg: 2.37 ± 1.68
3.16SerSer: 3.16 ± 1.974
3.949SerThr: 3.949 ± 1.555
1.58SerVal: 1.58 ± 0.698
0.0SerTrp: 0.0 ± 0.0
2.37SerTyr: 2.37 ± 1.273
0.0SerXaa: 0.0 ± 0.0
Thr
3.16ThrAla: 3.16 ± 0.583
0.0ThrCys: 0.0 ± 0.0
7.899ThrAsp: 7.899 ± 2.422
0.79ThrGlu: 0.79 ± 0.731
1.58ThrPhe: 1.58 ± 0.653
6.319ThrGly: 6.319 ± 1.757
0.79ThrHis: 0.79 ± 0.56
2.37ThrIle: 2.37 ± 1.036
1.58ThrLys: 1.58 ± 0.814
5.529ThrLeu: 5.529 ± 2.318
0.79ThrMet: 0.79 ± 1.22
2.37ThrAsn: 2.37 ± 1.033
3.16ThrPro: 3.16 ± 1.395
1.58ThrGln: 1.58 ± 0.653
0.79ThrArg: 0.79 ± 1.22
2.37ThrSer: 2.37 ± 0.969
1.58ThrThr: 1.58 ± 0.698
3.16ThrVal: 3.16 ± 1.691
0.0ThrTrp: 0.0 ± 0.0
2.37ThrTyr: 2.37 ± 1.361
0.0ThrXaa: 0.0 ± 0.0
Val
4.739ValAla: 4.739 ± 1.46
0.79ValCys: 0.79 ± 0.731
2.37ValAsp: 2.37 ± 1.68
3.16ValGlu: 3.16 ± 1.628
0.79ValPhe: 0.79 ± 0.56
1.58ValGly: 1.58 ± 0.814
0.79ValHis: 0.79 ± 0.735
0.79ValIle: 0.79 ± 0.735
2.37ValLys: 2.37 ± 2.59
1.58ValLeu: 1.58 ± 0.653
1.58ValMet: 1.58 ± 0.697
2.37ValAsn: 2.37 ± 1.273
4.739ValPro: 4.739 ± 0.782
1.58ValGln: 1.58 ± 0.698
4.739ValArg: 4.739 ± 1.283
4.739ValSer: 4.739 ± 2.563
1.58ValThr: 1.58 ± 0.698
1.58ValVal: 1.58 ± 0.814
0.0ValTrp: 0.0 ± 0.0
0.79ValTyr: 0.79 ± 0.735
0.0ValXaa: 0.0 ± 0.0
Trp
0.79TrpAla: 0.79 ± 0.56
0.0TrpCys: 0.0 ± 0.0
0.79TrpAsp: 0.79 ± 0.56
0.79TrpGlu: 0.79 ± 0.56
0.79TrpPhe: 0.79 ± 0.56
0.79TrpGly: 0.79 ± 0.56
2.37TrpHis: 2.37 ± 1.315
0.0TrpIle: 0.0 ± 0.0
0.79TrpLys: 0.79 ± 0.731
0.79TrpLeu: 0.79 ± 0.56
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.58TrpPro: 1.58 ± 1.12
0.79TrpGln: 0.79 ± 0.731
0.0TrpArg: 0.0 ± 0.0
1.58TrpSer: 1.58 ± 0.698
0.0TrpThr: 0.0 ± 0.0
0.79TrpVal: 0.79 ± 0.735
0.0TrpTrp: 0.0 ± 0.0
1.58TrpTyr: 1.58 ± 1.12
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.16TyrAla: 3.16 ± 1.604
0.79TyrCys: 0.79 ± 0.56
0.79TyrAsp: 0.79 ± 0.56
1.58TyrGlu: 1.58 ± 2.44
1.58TyrPhe: 1.58 ± 1.12
3.16TyrGly: 3.16 ± 1.009
1.58TyrHis: 1.58 ± 0.698
3.949TyrIle: 3.949 ± 0.899
1.58TyrLys: 1.58 ± 0.698
2.37TyrLeu: 2.37 ± 1.68
1.58TyrMet: 1.58 ± 1.462
2.37TyrAsn: 2.37 ± 1.273
2.37TyrPro: 2.37 ± 1.033
3.949TyrGln: 3.949 ± 1.555
1.58TyrArg: 1.58 ± 0.698
0.0TyrSer: 0.0 ± 0.0
4.739TyrThr: 4.739 ± 1.974
0.79TyrVal: 0.79 ± 0.731
2.37TyrTrp: 2.37 ± 1.68
3.16TyrTyr: 3.16 ± 2.01
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1267 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski