Amino acid dipepetide frequency for Shewanella woodyi (strain ATCC 51908 / MS32)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.234AlaAla: 7.234 ± 0.103	0.99AlaCys: 0.99 ± 0.03	4.507AlaAsp: 4.507 ± 0.064	5.314AlaGlu: 5.314 ± 0.079	3.204AlaPhe: 3.204 ± 0.052	5.924AlaGly: 5.924 ± 0.103	1.55AlaHis: 1.55 ± 0.038	5.85AlaIle: 5.85 ± 0.062	5.068AlaLys: 5.068 ± 0.082	9.157AlaLeu: 9.157 ± 0.107	2.42AlaMet: 2.42 ± 0.039	3.757AlaAsn: 3.757 ± 0.066	3.019AlaPro: 3.019 ± 0.123	3.702AlaGln: 3.702 ± 0.056	3.213AlaArg: 3.213 ± 0.064	5.683AlaSer: 5.683 ± 0.061	4.52AlaThr: 4.52 ± 0.197	5.337AlaVal: 5.337 ± 0.061	0.927AlaTrp: 0.927 ± 0.024	2.313AlaTyr: 2.313 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.744CysAla: 0.744 ± 0.024	0.152CysCys: 0.152 ± 0.01	0.626CysAsp: 0.626 ± 0.021	0.645CysGlu: 0.645 ± 0.023	0.494CysPhe: 0.494 ± 0.016	0.856CysGly: 0.856 ± 0.026	0.427CysHis: 0.427 ± 0.023	0.647CysIle: 0.647 ± 0.022	0.427CysLys: 0.427 ± 0.017	0.972CysLeu: 0.972 ± 0.031	0.225CysMet: 0.225 ± 0.014	0.383CysAsn: 0.383 ± 0.016	0.433CysPro: 0.433 ± 0.018	0.47CysGln: 0.47 ± 0.019	0.464CysArg: 0.464 ± 0.019	0.765CysSer: 0.765 ± 0.023	0.454CysThr: 0.454 ± 0.018	0.612CysVal: 0.612 ± 0.02	0.122CysTrp: 0.122 ± 0.009	0.342CysTyr: 0.342 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.516AspAla: 4.516 ± 0.152	0.533AspCys: 0.533 ± 0.02	3.116AspAsp: 3.116 ± 0.054	4.226AspGlu: 4.226 ± 0.059	2.471AspPhe: 2.471 ± 0.046	4.277AspGly: 4.277 ± 0.165	1.037AspHis: 1.037 ± 0.029	4.201AspIle: 4.201 ± 0.06	3.467AspLys: 3.467 ± 0.054	5.116AspLeu: 5.116 ± 0.064	1.413AspMet: 1.413 ± 0.037	2.836AspAsn: 2.836 ± 0.06	2.142AspPro: 2.142 ± 0.043	1.74AspGln: 1.74 ± 0.057	2.135AspArg: 2.135 ± 0.044	3.953AspSer: 3.953 ± 0.085	3.179AspThr: 3.179 ± 0.124	3.529AspVal: 3.529 ± 0.071	0.799AspTrp: 0.799 ± 0.025	2.013AspTyr: 2.013 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	5.027GluAla: 5.027 ± 0.079	0.489GluCys: 0.489 ± 0.019	2.888GluAsp: 2.888 ± 0.066	3.576GluGlu: 3.576 ± 0.067	2.526GluPhe: 2.526 ± 0.05	3.663GluGly: 3.663 ± 0.059	1.615GluHis: 1.615 ± 0.037	3.927GluIle: 3.927 ± 0.053	3.454GluLys: 3.454 ± 0.054	8.013GluLeu: 8.013 ± 0.116	1.742GluMet: 1.742 ± 0.038	2.428GluAsn: 2.428 ± 0.047	2.013GluPro: 2.013 ± 0.04	3.968GluGln: 3.968 ± 0.068	3.083GluArg: 3.083 ± 0.054	4.097GluSer: 4.097 ± 0.07	3.174GluThr: 3.174 ± 0.051	4.489GluVal: 4.489 ± 0.066	0.685GluTrp: 0.685 ± 0.024	1.852GluTyr: 1.852 ± 0.045	0.0GluXaa: 0.0 ± 0.0
Phe	3.342PheAla: 3.342 ± 0.061	0.481PheCys: 0.481 ± 0.019	2.848PheAsp: 2.848 ± 0.046	2.591PheGlu: 2.591 ± 0.043	1.665PhePhe: 1.665 ± 0.041	3.094PheGly: 3.094 ± 0.058	0.84PheHis: 0.84 ± 0.029	3.065PheIle: 3.065 ± 0.052	2.098PheLys: 2.098 ± 0.045	3.253PheLeu: 3.253 ± 0.053	1.024PheMet: 1.024 ± 0.026	2.279PheAsn: 2.279 ± 0.042	1.406PhePro: 1.406 ± 0.033	1.195PheGln: 1.195 ± 0.026	1.372PheArg: 1.372 ± 0.033	3.721PheSer: 3.721 ± 0.046	2.551PheThr: 2.551 ± 0.05	2.583PheVal: 2.583 ± 0.038	0.539PheTrp: 0.539 ± 0.018	1.404PheTyr: 1.404 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	5.46GlyAla: 5.46 ± 0.093	0.879GlyCys: 0.879 ± 0.026	3.949GlyAsp: 3.949 ± 0.071	4.673GlyGlu: 4.673 ± 0.067	3.395GlyPhe: 3.395 ± 0.048	4.865GlyGly: 4.865 ± 0.071	1.59GlyHis: 1.59 ± 0.036	4.554GlyIle: 4.554 ± 0.062	3.859GlyLys: 3.859 ± 0.07	7.046GlyLeu: 7.046 ± 0.069	1.927GlyMet: 1.927 ± 0.044	2.897GlyAsn: 2.897 ± 0.137	1.641GlyPro: 1.641 ± 0.033	2.794GlyGln: 2.794 ± 0.063	2.905GlyArg: 2.905 ± 0.049	4.618GlySer: 4.618 ± 0.103	3.796GlyThr: 3.796 ± 0.237	5.317GlyVal: 5.317 ± 0.071	0.935GlyTrp: 0.935 ± 0.03	2.631GlyTyr: 2.631 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.442HisAla: 1.442 ± 0.03	0.315HisCys: 0.315 ± 0.016	1.065HisAsp: 1.065 ± 0.025	1.151HisGlu: 1.151 ± 0.03	1.135HisPhe: 1.135 ± 0.033	1.538HisGly: 1.538 ± 0.039	0.649HisHis: 0.649 ± 0.021	1.31HisIle: 1.31 ± 0.032	1.116HisLys: 1.116 ± 0.029	2.317HisLeu: 2.317 ± 0.046	0.497HisMet: 0.497 ± 0.021	0.882HisAsn: 0.882 ± 0.025	1.045HisPro: 1.045 ± 0.031	1.182HisGln: 1.182 ± 0.033	0.921HisArg: 0.921 ± 0.027	1.552HisSer: 1.552 ± 0.036	1.071HisThr: 1.071 ± 0.028	1.08HisVal: 1.08 ± 0.028	0.361HisTrp: 0.361 ± 0.016	0.885HisTyr: 0.885 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.03IleAla: 6.03 ± 0.083	0.718IleCys: 0.718 ± 0.023	4.59IleAsp: 4.59 ± 0.096	4.832IleGlu: 4.832 ± 0.061	2.375IlePhe: 2.375 ± 0.042	4.528IleGly: 4.528 ± 0.061	1.191IleHis: 1.191 ± 0.032	3.767IleIle: 3.767 ± 0.054	3.616IleLys: 3.616 ± 0.061	5.456IleLeu: 5.456 ± 0.074	1.236IleMet: 1.236 ± 0.03	3.417IleAsn: 3.417 ± 0.111	2.533IlePro: 2.533 ± 0.043	2.145IleGln: 2.145 ± 0.041	2.532IleArg: 2.532 ± 0.048	5.149IleSer: 5.149 ± 0.07	3.91IleThr: 3.91 ± 0.135	3.687IleVal: 3.687 ± 0.051	0.678IleTrp: 0.678 ± 0.022	1.831IleTyr: 1.831 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.7LysAla: 4.7 ± 0.088	0.33LysCys: 0.33 ± 0.015	2.539LysAsp: 2.539 ± 0.043	3.376LysGlu: 3.376 ± 0.061	1.684LysPhe: 1.684 ± 0.031	3.494LysGly: 3.494 ± 0.055	1.243LysHis: 1.243 ± 0.032	3.021LysIle: 3.021 ± 0.054	2.693LysLys: 2.693 ± 0.052	6.035LysLeu: 6.035 ± 0.087	1.471LysMet: 1.471 ± 0.033	2.003LysAsn: 2.003 ± 0.041	2.276LysPro: 2.276 ± 0.042	3.054LysGln: 3.054 ± 0.06	2.755LysArg: 2.755 ± 0.056	3.558LysSer: 3.558 ± 0.062	2.748LysThr: 2.748 ± 0.05	3.943LysVal: 3.943 ± 0.061	0.564LysTrp: 0.564 ± 0.02	1.407LysTyr: 1.407 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	9.807LeuAla: 9.807 ± 0.117	1.123LeuCys: 1.123 ± 0.028	6.037LeuAsp: 6.037 ± 0.144	6.013LeuGlu: 6.013 ± 0.087	4.456LeuPhe: 4.456 ± 0.071	7.165LeuGly: 7.165 ± 0.084	1.937LeuHis: 1.937 ± 0.044	6.616LeuIle: 6.616 ± 0.085	5.664LeuLys: 5.664 ± 0.068	11.07LeuLeu: 11.07 ± 0.15	2.689LeuMet: 2.689 ± 0.049	4.913LeuAsn: 4.913 ± 0.064	4.661LeuPro: 4.661 ± 0.073	3.523LeuGln: 3.523 ± 0.054	3.772LeuArg: 3.772 ± 0.06	8.786LeuSer: 8.786 ± 0.111	6.618LeuThr: 6.618 ± 0.078	7.041LeuVal: 7.041 ± 0.088	1.115LeuTrp: 1.115 ± 0.029	2.819LeuTyr: 2.819 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.487MetAla: 2.487 ± 0.045	0.18MetCys: 0.18 ± 0.011	1.271MetAsp: 1.271 ± 0.03	1.3MetGlu: 1.3 ± 0.028	0.91MetPhe: 0.91 ± 0.025	1.768MetGly: 1.768 ± 0.045	0.462MetHis: 0.462 ± 0.017	1.388MetIle: 1.388 ± 0.034	1.563MetLys: 1.563 ± 0.038	2.933MetLeu: 2.933 ± 0.058	0.79MetMet: 0.79 ± 0.022	1.079MetAsn: 1.079 ± 0.027	1.151MetPro: 1.151 ± 0.029	1.045MetGln: 1.045 ± 0.026	1.092MetArg: 1.092 ± 0.027	2.008MetSer: 2.008 ± 0.036	1.596MetThr: 1.596 ± 0.035	1.696MetVal: 1.696 ± 0.039	0.216MetTrp: 0.216 ± 0.011	0.486MetTyr: 0.486 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.307AsnAla: 3.307 ± 0.048	0.451AsnCys: 0.451 ± 0.017	2.557AsnAsp: 2.557 ± 0.137	2.536AsnGlu: 2.536 ± 0.036	1.686AsnPhe: 1.686 ± 0.035	3.208AsnGly: 3.208 ± 0.111	0.934AsnHis: 0.934 ± 0.022	3.011AsnIle: 3.011 ± 0.045	2.288AsnLys: 2.288 ± 0.049	4.295AsnLeu: 4.295 ± 0.062	1.024AsnMet: 1.024 ± 0.028	2.03AsnAsn: 2.03 ± 0.063	2.004AsnPro: 2.004 ± 0.038	2.133AsnGln: 2.133 ± 0.039	2.144AsnArg: 2.144 ± 0.039	3.091AsnSer: 3.091 ± 0.043	2.526AsnThr: 2.526 ± 0.064	2.349AsnVal: 2.349 ± 0.048	0.652AsnTrp: 0.652 ± 0.021	1.424AsnTyr: 1.424 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	3.034ProAla: 3.034 ± 0.128	0.304ProCys: 0.304 ± 0.015	2.317ProAsp: 2.317 ± 0.046	3.05ProGlu: 3.05 ± 0.061	1.665ProPhe: 1.665 ± 0.035	2.246ProGly: 2.246 ± 0.039	0.841ProHis: 0.841 ± 0.024	2.472ProIle: 2.472 ± 0.04	2.197ProLys: 2.197 ± 0.042	4.093ProLeu: 4.093 ± 0.067	0.995ProMet: 0.995 ± 0.026	1.662ProAsn: 1.662 ± 0.039	1.075ProPro: 1.075 ± 0.028	1.678ProGln: 1.678 ± 0.036	1.203ProArg: 1.203 ± 0.034	2.623ProSer: 2.623 ± 0.047	2.052ProThr: 2.052 ± 0.06	2.912ProVal: 2.912 ± 0.048	0.515ProTrp: 0.515 ± 0.019	1.189ProTyr: 1.189 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	4.335GlnAla: 4.335 ± 0.059	0.377GlnCys: 0.377 ± 0.015	2.141GlnAsp: 2.141 ± 0.06	2.449GlnGlu: 2.449 ± 0.041	1.759GlnPhe: 1.759 ± 0.039	3.142GlnGly: 3.142 ± 0.051	1.07GlnHis: 1.07 ± 0.029	2.662GlnIle: 2.662 ± 0.06	1.986GlnLys: 1.986 ± 0.042	5.408GlnLeu: 5.408 ± 0.083	1.135GlnMet: 1.135 ± 0.026	1.489GlnAsn: 1.489 ± 0.034	1.465GlnPro: 1.465 ± 0.032	2.464GlnGln: 2.464 ± 0.06	1.944GlnArg: 1.944 ± 0.045	2.92GlnSer: 2.92 ± 0.051	2.324GlnThr: 2.324 ± 0.041	3.182GlnVal: 3.182 ± 0.053	0.592GlnTrp: 0.592 ± 0.021	1.459GlnTyr: 1.459 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	3.176ArgAla: 3.176 ± 0.055	0.439ArgCys: 0.439 ± 0.019	2.323ArgAsp: 2.323 ± 0.052	2.743ArgGlu: 2.743 ± 0.056	2.075ArgPhe: 2.075 ± 0.043	2.498ArgGly: 2.498 ± 0.043	1.014ArgHis: 1.014 ± 0.026	2.634ArgIle: 2.634 ± 0.052	2.127ArgLys: 2.127 ± 0.045	4.677ArgLeu: 4.677 ± 0.072	1.027ArgMet: 1.027 ± 0.028	1.635ArgAsn: 1.635 ± 0.038	1.408ArgPro: 1.408 ± 0.033	1.868ArgGln: 1.868 ± 0.042	2.027ArgArg: 2.027 ± 0.051	2.569ArgSer: 2.569 ± 0.043	1.969ArgThr: 1.969 ± 0.04	3.148ArgVal: 3.148 ± 0.05	0.571ArgTrp: 0.571 ± 0.018	1.694ArgTyr: 1.694 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.704SerAla: 5.704 ± 0.07	0.762SerCys: 0.762 ± 0.027	4.147SerAsp: 4.147 ± 0.062	4.45SerGlu: 4.45 ± 0.075	3.219SerPhe: 3.219 ± 0.057	5.487SerGly: 5.487 ± 0.085	1.672SerHis: 1.672 ± 0.036	4.572SerIle: 4.572 ± 0.066	3.467SerLys: 3.467 ± 0.058	7.973SerLeu: 7.973 ± 0.089	1.853SerMet: 1.853 ± 0.042	2.968SerAsn: 2.968 ± 0.056	2.771SerPro: 2.771 ± 0.048	3.411SerGln: 3.411 ± 0.056	2.98SerArg: 2.98 ± 0.054	5.449SerSer: 5.449 ± 0.078	3.556SerThr: 3.556 ± 0.054	4.796SerVal: 4.796 ± 0.056	0.956SerTrp: 0.956 ± 0.031	2.427SerTyr: 2.427 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.646ThrAla: 4.646 ± 0.116	0.535ThrCys: 0.535 ± 0.021	3.358ThrAsp: 3.358 ± 0.188	3.219ThrGlu: 3.219 ± 0.053	2.024ThrPhe: 2.024 ± 0.035	4.515ThrGly: 4.515 ± 0.184	1.143ThrHis: 1.143 ± 0.027	3.329ThrIle: 3.329 ± 0.094	2.338ThrLys: 2.338 ± 0.043	6.482ThrLeu: 6.482 ± 0.142	1.129ThrMet: 1.129 ± 0.037	2.199ThrAsn: 2.199 ± 0.064	2.887ThrPro: 2.887 ± 0.052	2.933ThrGln: 2.933 ± 0.057	2.13ThrArg: 2.13 ± 0.042	3.873ThrSer: 3.873 ± 0.067	2.726ThrThr: 2.726 ± 0.059	3.925ThrVal: 3.925 ± 0.266	0.58ThrTrp: 0.58 ± 0.02	1.498ThrTyr: 1.498 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	5.728ValAla: 5.728 ± 0.084	0.683ValCys: 0.683 ± 0.022	4.076ValAsp: 4.076 ± 0.057	4.474ValGlu: 4.474 ± 0.069	2.563ValPhe: 2.563 ± 0.047	4.39ValGly: 4.39 ± 0.07	1.122ValHis: 1.122 ± 0.029	4.785ValIle: 4.785 ± 0.081	3.576ValLys: 3.576 ± 0.059	6.305ValLeu: 6.305 ± 0.072	1.85ValMet: 1.85 ± 0.042	3.156ValAsn: 3.156 ± 0.047	2.367ValPro: 2.367 ± 0.042	2.158ValGln: 2.158 ± 0.043	2.534ValArg: 2.534 ± 0.049	5.087ValSer: 5.087 ± 0.068	4.668ValThr: 4.668 ± 0.31	4.765ValVal: 4.765 ± 0.146	0.732ValTrp: 0.732 ± 0.024	1.811ValTyr: 1.811 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.8TrpAla: 0.8 ± 0.024	0.15TrpCys: 0.15 ± 0.009	0.648TrpAsp: 0.648 ± 0.022	0.568TrpGlu: 0.568 ± 0.018	0.563TrpPhe: 0.563 ± 0.019	0.823TrpGly: 0.823 ± 0.023	0.37TrpHis: 0.37 ± 0.015	0.643TrpIle: 0.643 ± 0.02	0.516TrpLys: 0.516 ± 0.017	1.57TrpLeu: 1.57 ± 0.039	0.312TrpMet: 0.312 ± 0.014	0.454TrpAsn: 0.454 ± 0.018	0.474TrpPro: 0.474 ± 0.019	0.874TrpGln: 0.874 ± 0.026	0.69TrpArg: 0.69 ± 0.023	0.857TrpSer: 0.857 ± 0.027	0.517TrpThr: 0.517 ± 0.021	0.797TrpVal: 0.797 ± 0.029	0.173TrpTrp: 0.173 ± 0.01	0.369TrpTyr: 0.369 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.169TyrAla: 2.169 ± 0.043	0.371TyrCys: 0.371 ± 0.016	1.698TyrAsp: 1.698 ± 0.046	1.522TyrGlu: 1.522 ± 0.036	1.482TyrPhe: 1.482 ± 0.033	2.249TyrGly: 2.249 ± 0.055	0.806TyrHis: 0.806 ± 0.025	1.769TyrIle: 1.769 ± 0.037	1.374TyrLys: 1.374 ± 0.033	3.652TyrLeu: 3.652 ± 0.059	0.661TyrMet: 0.661 ± 0.02	1.182TyrAsn: 1.182 ± 0.033	1.353TyrPro: 1.353 ± 0.032	1.963TyrGln: 1.963 ± 0.046	1.724TyrArg: 1.724 ± 0.047	2.263TyrSer: 2.263 ± 0.047	1.515TyrThr: 1.515 ± 0.039	1.647TyrVal: 1.647 ± 0.032	0.455TyrTrp: 0.455 ± 0.014	1.051TyrTyr: 1.051 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4865 proteins (1675288 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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