Amino acid dipepetide frequency for Mucilaginibacter yixingensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.675AlaAla: 7.675 ± 0.109	0.761AlaCys: 0.761 ± 0.024	5.401AlaAsp: 5.401 ± 0.07	4.435AlaGlu: 4.435 ± 0.064	3.56AlaPhe: 3.56 ± 0.054	6.593AlaGly: 6.593 ± 0.069	1.479AlaHis: 1.479 ± 0.035	5.382AlaIle: 5.382 ± 0.069	4.586AlaLys: 4.586 ± 0.066	7.47AlaLeu: 7.47 ± 0.082	1.966AlaMet: 1.966 ± 0.041	4.02AlaAsn: 4.02 ± 0.064	2.826AlaPro: 2.826 ± 0.053	3.653AlaGln: 3.653 ± 0.045	3.047AlaArg: 3.047 ± 0.046	4.677AlaSer: 4.677 ± 0.067	4.733AlaThr: 4.733 ± 0.085	5.373AlaVal: 5.373 ± 0.072	0.956AlaTrp: 0.956 ± 0.028	3.079AlaTyr: 3.079 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.62CysAla: 0.62 ± 0.021	0.138CysCys: 0.138 ± 0.008	0.422CysAsp: 0.422 ± 0.018	0.347CysGlu: 0.347 ± 0.017	0.485CysPhe: 0.485 ± 0.021	0.674CysGly: 0.674 ± 0.023	0.219CysHis: 0.219 ± 0.014	0.598CysIle: 0.598 ± 0.024	0.485CysLys: 0.485 ± 0.019	0.866CysLeu: 0.866 ± 0.026	0.192CysMet: 0.192 ± 0.011	0.385CysAsn: 0.385 ± 0.016	0.338CysPro: 0.338 ± 0.015	0.269CysGln: 0.269 ± 0.015	0.38CysArg: 0.38 ± 0.016	0.569CysSer: 0.569 ± 0.02	0.49CysThr: 0.49 ± 0.018	0.513CysVal: 0.513 ± 0.02	0.117CysTrp: 0.117 ± 0.009	0.333CysTyr: 0.333 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.727AspAla: 4.727 ± 0.066	0.406AspCys: 0.406 ± 0.018	2.924AspAsp: 2.924 ± 0.053	3.371AspGlu: 3.371 ± 0.057	2.898AspPhe: 2.898 ± 0.05	4.156AspGly: 4.156 ± 0.061	1.149AspHis: 1.149 ± 0.028	3.72AspIle: 3.72 ± 0.053	3.597AspLys: 3.597 ± 0.058	4.973AspLeu: 4.973 ± 0.061	1.295AspMet: 1.295 ± 0.037	2.79AspAsn: 2.79 ± 0.048	2.219AspPro: 2.219 ± 0.038	2.022AspGln: 2.022 ± 0.038	2.349AspArg: 2.349 ± 0.039	2.78AspSer: 2.78 ± 0.049	2.864AspThr: 2.864 ± 0.05	3.781AspVal: 3.781 ± 0.048	0.777AspTrp: 0.777 ± 0.022	2.68AspTyr: 2.68 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.175GluAla: 4.175 ± 0.061	0.33GluCys: 0.33 ± 0.013	2.509GluAsp: 2.509 ± 0.053	3.004GluGlu: 3.004 ± 0.059	2.099GluPhe: 2.099 ± 0.042	3.164GluGly: 3.164 ± 0.048	1.202GluHis: 1.202 ± 0.033	3.464GluIle: 3.464 ± 0.055	3.597GluLys: 3.597 ± 0.062	5.237GluLeu: 5.237 ± 0.074	1.367GluMet: 1.367 ± 0.031	2.576GluAsn: 2.576 ± 0.047	1.726GluPro: 1.726 ± 0.039	2.534GluGln: 2.534 ± 0.052	2.569GluArg: 2.569 ± 0.053	2.357GluSer: 2.357 ± 0.046	2.654GluThr: 2.654 ± 0.047	3.485GluVal: 3.485 ± 0.057	0.672GluTrp: 0.672 ± 0.021	1.86GluTyr: 1.86 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.423PheAla: 3.423 ± 0.05	0.495PheCys: 0.495 ± 0.019	2.925PheAsp: 2.925 ± 0.041	2.476PheGlu: 2.476 ± 0.036	2.225PhePhe: 2.225 ± 0.041	3.301PheGly: 3.301 ± 0.046	0.811PheHis: 0.811 ± 0.022	3.145PheIle: 3.145 ± 0.047	3.216PheLys: 3.216 ± 0.048	3.89PheLeu: 3.89 ± 0.057	1.139PheMet: 1.139 ± 0.028	2.925PheAsn: 2.925 ± 0.046	1.634PhePro: 1.634 ± 0.032	1.307PheGln: 1.307 ± 0.032	1.816PheArg: 1.816 ± 0.033	3.318PheSer: 3.318 ± 0.055	3.059PheThr: 3.059 ± 0.05	2.791PheVal: 2.791 ± 0.046	0.576PheTrp: 0.576 ± 0.021	2.135PheTyr: 2.135 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	5.219GlyAla: 5.219 ± 0.075	0.66GlyCys: 0.66 ± 0.025	3.668GlyAsp: 3.668 ± 0.058	3.208GlyGlu: 3.208 ± 0.049	3.539GlyPhe: 3.539 ± 0.051	5.415GlyGly: 5.415 ± 0.092	1.437GlyHis: 1.437 ± 0.031	4.993GlyIle: 4.993 ± 0.061	5.074GlyLys: 5.074 ± 0.067	6.513GlyLeu: 6.513 ± 0.069	1.792GlyMet: 1.792 ± 0.035	3.803GlyAsn: 3.803 ± 0.066	1.844GlyPro: 1.844 ± 0.037	2.655GlyGln: 2.655 ± 0.045	2.963GlyArg: 2.963 ± 0.045	4.554GlySer: 4.554 ± 0.074	4.512GlyThr: 4.512 ± 0.076	4.656GlyVal: 4.656 ± 0.063	1.016GlyTrp: 1.016 ± 0.028	3.215GlyTyr: 3.215 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.323HisAla: 1.323 ± 0.033	0.213HisCys: 0.213 ± 0.012	1.06HisAsp: 1.06 ± 0.026	1.04HisGlu: 1.04 ± 0.022	1.159HisPhe: 1.159 ± 0.033	1.356HisGly: 1.356 ± 0.035	0.645HisHis: 0.645 ± 0.022	1.492HisIle: 1.492 ± 0.037	1.023HisLys: 1.023 ± 0.023	2.03HisLeu: 2.03 ± 0.034	0.42HisMet: 0.42 ± 0.017	1.046HisAsn: 1.046 ± 0.026	1.133HisPro: 1.133 ± 0.029	0.958HisGln: 0.958 ± 0.027	0.906HisArg: 0.906 ± 0.026	1.03HisSer: 1.03 ± 0.026	1.182HisThr: 1.182 ± 0.027	1.188HisVal: 1.188 ± 0.031	0.301HisTrp: 0.301 ± 0.015	0.997HisTyr: 0.997 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.771IleAla: 5.771 ± 0.071	0.712IleCys: 0.712 ± 0.023	4.16IleAsp: 4.16 ± 0.052	3.448IleGlu: 3.448 ± 0.057	2.733IlePhe: 2.733 ± 0.048	4.678IleGly: 4.678 ± 0.067	1.254IleHis: 1.254 ± 0.03	4.539IleIle: 4.539 ± 0.07	4.46IleLys: 4.46 ± 0.061	5.404IleLeu: 5.404 ± 0.073	1.284IleMet: 1.284 ± 0.03	4.081IleAsn: 4.081 ± 0.055	2.827IlePro: 2.827 ± 0.046	2.021IleGln: 2.021 ± 0.036	2.823IleArg: 2.823 ± 0.044	4.645IleSer: 4.645 ± 0.057	4.614IleThr: 4.614 ± 0.058	3.927IleVal: 3.927 ± 0.058	0.737IleTrp: 0.737 ± 0.022	2.627IleTyr: 2.627 ± 0.046	0.0IleXaa: 0.0 ± 0.0
Lys	5.342LysAla: 5.342 ± 0.066	0.322LysCys: 0.322 ± 0.016	3.72LysAsp: 3.72 ± 0.062	3.565LysGlu: 3.565 ± 0.066	2.332LysPhe: 2.332 ± 0.042	4.177LysGly: 4.177 ± 0.061	1.257LysHis: 1.257 ± 0.029	4.057LysIle: 4.057 ± 0.053	4.513LysLys: 4.513 ± 0.063	5.879LysLeu: 5.879 ± 0.068	1.716LysMet: 1.716 ± 0.04	3.568LysAsn: 3.568 ± 0.052	2.945LysPro: 2.945 ± 0.049	2.794LysGln: 2.794 ± 0.041	2.667LysArg: 2.667 ± 0.042	3.356LysSer: 3.356 ± 0.05	3.96LysThr: 3.96 ± 0.05	4.145LysVal: 4.145 ± 0.05	0.755LysTrp: 0.755 ± 0.024	2.634LysTyr: 2.634 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	7.415LeuAla: 7.415 ± 0.068	0.907LeuCys: 0.907 ± 0.024	4.654LeuAsp: 4.654 ± 0.059	4.174LeuGlu: 4.174 ± 0.057	4.386LeuPhe: 4.386 ± 0.059	5.789LeuGly: 5.789 ± 0.068	1.974LeuHis: 1.974 ± 0.033	6.207LeuIle: 6.207 ± 0.071	6.709LeuLys: 6.709 ± 0.08	9.532LeuLeu: 9.532 ± 0.095	2.332LeuMet: 2.332 ± 0.043	5.362LeuAsn: 5.362 ± 0.063	4.265LeuPro: 4.265 ± 0.051	3.867LeuGln: 3.867 ± 0.059	3.915LeuArg: 3.915 ± 0.059	6.578LeuSer: 6.578 ± 0.071	5.694LeuThr: 5.694 ± 0.074	5.558LeuVal: 5.558 ± 0.072	1.015LeuTrp: 1.015 ± 0.027	3.296LeuTyr: 3.296 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.086MetAla: 2.086 ± 0.036	0.154MetCys: 0.154 ± 0.01	1.255MetAsp: 1.255 ± 0.031	1.233MetGlu: 1.233 ± 0.031	0.878MetPhe: 0.878 ± 0.022	1.551MetGly: 1.551 ± 0.034	0.487MetHis: 0.487 ± 0.018	1.49MetIle: 1.49 ± 0.035	1.83MetLys: 1.83 ± 0.033	2.279MetLeu: 2.279 ± 0.041	0.685MetMet: 0.685 ± 0.023	1.18MetAsn: 1.18 ± 0.03	1.211MetPro: 1.211 ± 0.028	1.042MetGln: 1.042 ± 0.029	1.143MetArg: 1.143 ± 0.023	1.36MetSer: 1.36 ± 0.033	1.181MetThr: 1.181 ± 0.032	1.58MetVal: 1.58 ± 0.039	0.217MetTrp: 0.217 ± 0.013	0.688MetTyr: 0.688 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.255AsnAla: 4.255 ± 0.065	0.45AsnCys: 0.45 ± 0.021	2.85AsnAsp: 2.85 ± 0.041	2.497AsnGlu: 2.497 ± 0.048	2.457AsnPhe: 2.457 ± 0.042	4.24AsnGly: 4.24 ± 0.066	1.074AsnHis: 1.074 ± 0.026	3.856AsnIle: 3.856 ± 0.052	3.157AsnLys: 3.157 ± 0.048	4.841AsnLeu: 4.841 ± 0.067	1.217AsnMet: 1.217 ± 0.031	3.357AsnAsn: 3.357 ± 0.064	2.669AsnPro: 2.669 ± 0.048	2.193AsnGln: 2.193 ± 0.042	2.35AsnArg: 2.35 ± 0.044	3.077AsnSer: 3.077 ± 0.054	3.362AsnThr: 3.362 ± 0.059	3.458AsnVal: 3.458 ± 0.051	0.811AsnTrp: 0.811 ± 0.023	2.672AsnTyr: 2.672 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	3.9ProAla: 3.9 ± 0.067	0.24ProCys: 0.24 ± 0.011	2.844ProAsp: 2.844 ± 0.046	2.7ProGlu: 2.7 ± 0.044	1.887ProPhe: 1.887 ± 0.038	3.152ProGly: 3.152 ± 0.047	0.8ProHis: 0.8 ± 0.023	2.329ProIle: 2.329 ± 0.04	2.135ProLys: 2.135 ± 0.037	3.482ProLeu: 3.482 ± 0.049	0.823ProMet: 0.823 ± 0.021	2.049ProAsn: 2.049 ± 0.041	1.224ProPro: 1.224 ± 0.035	1.735ProGln: 1.735 ± 0.036	1.267ProArg: 1.267 ± 0.031	2.333ProSer: 2.333 ± 0.04	2.194ProThr: 2.194 ± 0.046	3.442ProVal: 3.442 ± 0.053	0.461ProTrp: 0.461 ± 0.017	1.633ProTyr: 1.633 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.178GlnAla: 3.178 ± 0.046	0.234GlnCys: 0.234 ± 0.013	1.702GlnAsp: 1.702 ± 0.034	1.84GlnGlu: 1.84 ± 0.042	1.7GlnPhe: 1.7 ± 0.036	2.269GlnGly: 2.269 ± 0.042	0.993GlnHis: 0.993 ± 0.024	2.534GlnIle: 2.534 ± 0.046	2.555GlnLys: 2.555 ± 0.04	4.34GlnLeu: 4.34 ± 0.063	1.039GlnMet: 1.039 ± 0.027	2.179GlnAsn: 2.179 ± 0.044	1.831GlnPro: 1.831 ± 0.036	2.589GlnGln: 2.589 ± 0.077	1.744GlnArg: 1.744 ± 0.04	2.359GlnSer: 2.359 ± 0.041	2.506GlnThr: 2.506 ± 0.048	2.572GlnVal: 2.572 ± 0.044	0.502GlnTrp: 0.502 ± 0.018	1.67GlnTyr: 1.67 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.894ArgAla: 2.894 ± 0.041	0.286ArgCys: 0.286 ± 0.014	2.171ArgAsp: 2.171 ± 0.042	2.196ArgGlu: 2.196 ± 0.044	2.289ArgPhe: 2.289 ± 0.038	2.399ArgGly: 2.399 ± 0.043	0.886ArgHis: 0.886 ± 0.024	2.996ArgIle: 2.996 ± 0.041	2.764ArgLys: 2.764 ± 0.049	4.107ArgLeu: 4.107 ± 0.052	1.171ArgMet: 1.171 ± 0.028	2.29ArgAsn: 2.29 ± 0.041	1.589ArgPro: 1.589 ± 0.03	1.761ArgGln: 1.761 ± 0.039	1.873ArgArg: 1.873 ± 0.036	2.408ArgSer: 2.408 ± 0.038	2.301ArgThr: 2.301 ± 0.037	2.68ArgVal: 2.68 ± 0.048	0.623ArgTrp: 0.623 ± 0.02	2.035ArgTyr: 2.035 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.119SerAla: 5.119 ± 0.06	0.539SerCys: 0.539 ± 0.019	2.975SerAsp: 2.975 ± 0.049	2.476SerGlu: 2.476 ± 0.038	3.297SerPhe: 3.297 ± 0.051	4.945SerGly: 4.945 ± 0.074	1.16SerHis: 1.16 ± 0.028	4.186SerIle: 4.186 ± 0.056	3.475SerLys: 3.475 ± 0.049	5.748SerLeu: 5.748 ± 0.063	1.269SerMet: 1.269 ± 0.03	3.092SerAsn: 3.092 ± 0.052	2.472SerPro: 2.472 ± 0.036	1.947SerGln: 1.947 ± 0.036	2.433SerArg: 2.433 ± 0.038	3.772SerSer: 3.772 ± 0.07	3.665SerThr: 3.665 ± 0.068	4.268SerVal: 4.268 ± 0.055	0.706SerTrp: 0.706 ± 0.022	2.737SerTyr: 2.737 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	5.327ThrAla: 5.327 ± 0.081	0.415ThrCys: 0.415 ± 0.018	3.693ThrAsp: 3.693 ± 0.055	2.914ThrGlu: 2.914 ± 0.047	2.782ThrPhe: 2.782 ± 0.048	5.151ThrGly: 5.151 ± 0.08	1.132ThrHis: 1.132 ± 0.028	4.078ThrIle: 4.078 ± 0.057	2.913ThrLys: 2.913 ± 0.047	5.618ThrLeu: 5.618 ± 0.063	1.099ThrMet: 1.099 ± 0.027	3.031ThrAsn: 3.031 ± 0.055	2.983ThrPro: 2.983 ± 0.053	2.151ThrGln: 2.151 ± 0.044	2.279ThrArg: 2.279 ± 0.042	3.52ThrSer: 3.52 ± 0.065	3.846ThrThr: 3.846 ± 0.076	4.272ThrVal: 4.272 ± 0.075	0.734ThrTrp: 0.734 ± 0.024	2.617ThrTyr: 2.617 ± 0.058	0.0ThrXaa: 0.0 ± 0.0
Val	5.235ValAla: 5.235 ± 0.063	0.644ValCys: 0.644 ± 0.022	3.531ValAsp: 3.531 ± 0.055	3.146ValGlu: 3.146 ± 0.051	3.124ValPhe: 3.124 ± 0.048	3.874ValGly: 3.874 ± 0.058	1.163ValHis: 1.163 ± 0.03	4.628ValIle: 4.628 ± 0.06	4.447ValLys: 4.447 ± 0.058	6.128ValLeu: 6.128 ± 0.071	1.583ValMet: 1.583 ± 0.035	3.777ValAsn: 3.777 ± 0.06	2.643ValPro: 2.643 ± 0.043	2.219ValGln: 2.219 ± 0.039	2.568ValArg: 2.568 ± 0.042	4.318ValSer: 4.318 ± 0.069	4.298ValThr: 4.298 ± 0.075	4.49ValVal: 4.49 ± 0.065	0.757ValTrp: 0.757 ± 0.024	2.704ValTyr: 2.704 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.907TrpAla: 0.907 ± 0.021	0.146TrpCys: 0.146 ± 0.009	0.678TrpAsp: 0.678 ± 0.021	0.638TrpGlu: 0.638 ± 0.022	0.614TrpPhe: 0.614 ± 0.02	0.88TrpGly: 0.88 ± 0.025	0.35TrpHis: 0.35 ± 0.017	0.693TrpIle: 0.693 ± 0.023	0.7TrpLys: 0.7 ± 0.018	1.317TrpLeu: 1.317 ± 0.036	0.356TrpMet: 0.356 ± 0.016	0.674TrpAsn: 0.674 ± 0.022	0.436TrpPro: 0.436 ± 0.02	0.642TrpGln: 0.642 ± 0.021	0.577TrpArg: 0.577 ± 0.019	0.679TrpSer: 0.679 ± 0.021	0.719TrpThr: 0.719 ± 0.021	0.795TrpVal: 0.795 ± 0.022	0.22TrpTrp: 0.22 ± 0.012	0.533TrpTyr: 0.533 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.08TyrAla: 3.08 ± 0.046	0.388TyrCys: 0.388 ± 0.015	2.337TyrAsp: 2.337 ± 0.043	1.871TyrGlu: 1.871 ± 0.034	2.163TyrPhe: 2.163 ± 0.038	2.973TyrGly: 2.973 ± 0.053	1.028TyrHis: 1.028 ± 0.026	2.363TyrIle: 2.363 ± 0.039	2.466TyrLys: 2.466 ± 0.041	3.974TyrLeu: 3.974 ± 0.059	0.782TyrMet: 0.782 ± 0.021	2.657TyrAsn: 2.657 ± 0.053	1.818TyrPro: 1.818 ± 0.036	1.977TyrGln: 1.977 ± 0.042	2.05TyrArg: 2.05 ± 0.045	2.59TyrSer: 2.59 ± 0.047	2.722TyrThr: 2.722 ± 0.047	2.303TyrVal: 2.303 ± 0.041	0.601TyrTrp: 0.601 ± 0.022	2.039TyrTyr: 2.039 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4440 proteins (1570352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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