Amino acid dipepetide frequency for Luteibaculum oceani

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.777AlaAla: 4.777 ± 0.09
0.801AlaCys: 0.801 ± 0.034
3.498AlaAsp: 3.498 ± 0.065
4.384AlaGlu: 4.384 ± 0.084
3.402AlaPhe: 3.402 ± 0.078
5.016AlaGly: 5.016 ± 0.109
1.132AlaHis: 1.132 ± 0.038
5.036AlaIle: 5.036 ± 0.101
4.789AlaLys: 4.789 ± 0.101
6.425AlaLeu: 6.425 ± 0.118
1.433AlaMet: 1.433 ± 0.039
3.527AlaAsn: 3.527 ± 0.078
2.471AlaPro: 2.471 ± 0.066
2.515AlaGln: 2.515 ± 0.058
2.355AlaArg: 2.355 ± 0.06
4.336AlaSer: 4.336 ± 0.067
3.583AlaThr: 3.583 ± 0.086
4.321AlaVal: 4.321 ± 0.077
0.735AlaTrp: 0.735 ± 0.029
2.505AlaTyr: 2.505 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.644CysAla: 0.644 ± 0.03
0.134CysCys: 0.134 ± 0.013
0.629CysAsp: 0.629 ± 0.039
0.778CysGlu: 0.778 ± 0.041
0.551CysPhe: 0.551 ± 0.031
0.872CysGly: 0.872 ± 0.034
0.191CysHis: 0.191 ± 0.016
0.716CysIle: 0.716 ± 0.028
0.646CysLys: 0.646 ± 0.026
0.824CysLeu: 0.824 ± 0.034
0.16CysMet: 0.16 ± 0.015
0.558CysAsn: 0.558 ± 0.027
0.502CysPro: 0.502 ± 0.034
0.355CysGln: 0.355 ± 0.025
0.335CysArg: 0.335 ± 0.021
0.839CysSer: 0.839 ± 0.034
0.554CysThr: 0.554 ± 0.032
0.593CysVal: 0.593 ± 0.027
0.077CysTrp: 0.077 ± 0.009
0.374CysTyr: 0.374 ± 0.022
0.0CysXaa: 0.0 ± 0.0
Asp
3.757AspAla: 3.757 ± 0.078
0.515AspCys: 0.515 ± 0.029
2.516AspAsp: 2.516 ± 0.065
3.5AspGlu: 3.5 ± 0.071
3.539AspPhe: 3.539 ± 0.071
4.076AspGly: 4.076 ± 0.099
0.98AspHis: 0.98 ± 0.03
3.954AspIle: 3.954 ± 0.064
3.457AspLys: 3.457 ± 0.074
5.519AspLeu: 5.519 ± 0.087
0.959AspMet: 0.959 ± 0.031
2.89AspAsn: 2.89 ± 0.067
2.434AspPro: 2.434 ± 0.067
2.028AspGln: 2.028 ± 0.054
2.129AspArg: 2.129 ± 0.053
3.656AspSer: 3.656 ± 0.109
3.029AspThr: 3.029 ± 0.101
3.336AspVal: 3.336 ± 0.064
0.705AspTrp: 0.705 ± 0.028
2.467AspTyr: 2.467 ± 0.056
0.0AspXaa: 0.0 ± 0.0
Glu
4.515GluAla: 4.515 ± 0.099
0.39GluCys: 0.39 ± 0.02
3.607GluAsp: 3.607 ± 0.068
5.204GluGlu: 5.204 ± 0.122
3.189GluPhe: 3.189 ± 0.067
4.029GluGly: 4.029 ± 0.082
1.128GluHis: 1.128 ± 0.04
6.026GluIle: 6.026 ± 0.087
5.487GluLys: 5.487 ± 0.129
6.755GluLeu: 6.755 ± 0.108
1.516GluMet: 1.516 ± 0.048
4.291GluAsn: 4.291 ± 0.068
1.801GluPro: 1.801 ± 0.052
2.501GluGln: 2.501 ± 0.067
2.51GluArg: 2.51 ± 0.067
3.517GluSer: 3.517 ± 0.065
3.164GluThr: 3.164 ± 0.063
4.623GluVal: 4.623 ± 0.078
0.703GluTrp: 0.703 ± 0.031
2.204GluTyr: 2.204 ± 0.048
0.0GluXaa: 0.0 ± 0.0
Phe
3.108PheAla: 3.108 ± 0.061
0.633PheCys: 0.633 ± 0.026
3.034PheAsp: 3.034 ± 0.064
3.321PheGlu: 3.321 ± 0.06
2.55PhePhe: 2.55 ± 0.067
3.775PheGly: 3.775 ± 0.079
0.855PheHis: 0.855 ± 0.033
3.435PheIle: 3.435 ± 0.067
3.465PheLys: 3.465 ± 0.076
4.628PheLeu: 4.628 ± 0.096
0.968PheMet: 0.968 ± 0.033
3.172PheAsn: 3.172 ± 0.077
1.911PhePro: 1.911 ± 0.047
1.745PheGln: 1.745 ± 0.04
1.874PheArg: 1.874 ± 0.048
4.071PheSer: 4.071 ± 0.068
3.189PheThr: 3.189 ± 0.079
3.09PheVal: 3.09 ± 0.064
0.652PheTrp: 0.652 ± 0.03
2.029PheTyr: 2.029 ± 0.061
0.0PheXaa: 0.0 ± 0.0
Gly
4.77GlyAla: 4.77 ± 0.091
1.02GlyCys: 1.02 ± 0.066
3.965GlyAsp: 3.965 ± 0.1
4.354GlyGlu: 4.354 ± 0.084
3.73GlyPhe: 3.73 ± 0.061
5.275GlyGly: 5.275 ± 0.116
1.148GlyHis: 1.148 ± 0.043
5.346GlyIle: 5.346 ± 0.088
5.285GlyLys: 5.285 ± 0.088
6.25GlyLeu: 6.25 ± 0.093
1.593GlyMet: 1.593 ± 0.05
4.192GlyAsn: 4.192 ± 0.096
1.855GlyPro: 1.855 ± 0.055
2.125GlyGln: 2.125 ± 0.058
2.413GlyArg: 2.413 ± 0.058
4.626GlySer: 4.626 ± 0.105
4.174GlyThr: 4.174 ± 0.099
4.857GlyVal: 4.857 ± 0.085
0.84GlyTrp: 0.84 ± 0.031
2.763GlyTyr: 2.763 ± 0.071
0.0GlyXaa: 0.0 ± 0.0
His
1.056HisAla: 1.056 ± 0.038
0.228HisCys: 0.228 ± 0.018
0.749HisAsp: 0.749 ± 0.026
0.98HisGlu: 0.98 ± 0.033
1.118HisPhe: 1.118 ± 0.038
1.12HisGly: 1.12 ± 0.04
0.484HisHis: 0.484 ± 0.025
1.23HisIle: 1.23 ± 0.032
1.114HisLys: 1.114 ± 0.04
1.859HisLeu: 1.859 ± 0.059
0.316HisMet: 0.316 ± 0.02
0.888HisAsn: 0.888 ± 0.037
1.066HisPro: 1.066 ± 0.037
0.716HisGln: 0.716 ± 0.028
0.778HisArg: 0.778 ± 0.031
1.016HisSer: 1.016 ± 0.035
0.856HisThr: 0.856 ± 0.032
0.959HisVal: 0.959 ± 0.032
0.218HisTrp: 0.218 ± 0.016
0.792HisTyr: 0.792 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.293IleAla: 5.293 ± 0.094
0.894IleCys: 0.894 ± 0.039
4.279IleAsp: 4.279 ± 0.068
4.918IleGlu: 4.918 ± 0.084
3.266IlePhe: 3.266 ± 0.063
4.713IleGly: 4.713 ± 0.085
1.342IleHis: 1.342 ± 0.045
4.772IleIle: 4.772 ± 0.085
4.942IleLys: 4.942 ± 0.099
6.413IleLeu: 6.413 ± 0.124
1.112IleMet: 1.112 ± 0.041
4.244IleAsn: 4.244 ± 0.074
3.426IlePro: 3.426 ± 0.063
2.477IleGln: 2.477 ± 0.057
2.696IleArg: 2.696 ± 0.056
5.843IleSer: 5.843 ± 0.079
4.138IleThr: 4.138 ± 0.082
4.127IleVal: 4.127 ± 0.073
0.756IleTrp: 0.756 ± 0.03
2.458IleTyr: 2.458 ± 0.049
0.0IleXaa: 0.0 ± 0.0
Lys
5.023LysAla: 5.023 ± 0.097
0.406LysCys: 0.406 ± 0.021
3.852LysAsp: 3.852 ± 0.081
5.687LysGlu: 5.687 ± 0.138
2.756LysPhe: 2.756 ± 0.056
4.523LysGly: 4.523 ± 0.088
1.272LysHis: 1.272 ± 0.044
5.012LysIle: 5.012 ± 0.092
5.608LysLys: 5.608 ± 0.124
6.363LysLeu: 6.363 ± 0.101
1.668LysMet: 1.668 ± 0.049
3.997LysAsn: 3.997 ± 0.074
2.628LysPro: 2.628 ± 0.053
2.389LysGln: 2.389 ± 0.063
2.771LysArg: 2.771 ± 0.067
4.67LysSer: 4.67 ± 0.088
3.567LysThr: 3.567 ± 0.067
4.493LysVal: 4.493 ± 0.093
0.764LysTrp: 0.764 ± 0.03
2.623LysTyr: 2.623 ± 0.064
0.0LysXaa: 0.0 ± 0.0
Leu
6.414LeuAla: 6.414 ± 0.1
0.98LeuCys: 0.98 ± 0.035
5.466LeuAsp: 5.466 ± 0.086
6.387LeuGlu: 6.387 ± 0.11
4.705LeuPhe: 4.705 ± 0.104
6.445LeuGly: 6.445 ± 0.103
1.541LeuHis: 1.541 ± 0.045
6.552LeuIle: 6.552 ± 0.113
7.137LeuLys: 7.137 ± 0.128
8.577LeuLeu: 8.577 ± 0.157
1.847LeuMet: 1.847 ± 0.048
5.748LeuAsn: 5.748 ± 0.096
3.874LeuPro: 3.874 ± 0.065
2.914LeuGln: 2.914 ± 0.064
3.692LeuArg: 3.692 ± 0.074
6.91LeuSer: 6.91 ± 0.11
4.648LeuThr: 4.648 ± 0.083
5.945LeuVal: 5.945 ± 0.106
0.888LeuTrp: 0.888 ± 0.032
3.031LeuTyr: 3.031 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
1.667MetAla: 1.667 ± 0.048
0.141MetCys: 0.141 ± 0.013
1.348MetAsp: 1.348 ± 0.04
1.481MetGlu: 1.481 ± 0.045
0.666MetPhe: 0.666 ± 0.028
1.549MetGly: 1.549 ± 0.053
0.404MetHis: 0.404 ± 0.025
1.134MetIle: 1.134 ± 0.037
1.502MetLys: 1.502 ± 0.04
1.821MetLeu: 1.821 ± 0.051
0.412MetMet: 0.412 ± 0.023
0.857MetAsn: 0.857 ± 0.031
0.801MetPro: 0.801 ± 0.03
0.655MetGln: 0.655 ± 0.028
0.928MetArg: 0.928 ± 0.031
1.131MetSer: 1.131 ± 0.037
0.745MetThr: 0.745 ± 0.03
1.428MetVal: 1.428 ± 0.039
0.156MetTrp: 0.156 ± 0.012
0.601MetTyr: 0.601 ± 0.031
0.0MetXaa: 0.0 ± 0.0
Asn
3.832AsnAla: 3.832 ± 0.069
0.666AsnCys: 0.666 ± 0.036
2.729AsnAsp: 2.729 ± 0.079
3.266AsnGlu: 3.266 ± 0.066
3.074AsnPhe: 3.074 ± 0.071
4.543AsnGly: 4.543 ± 0.124
1.06AsnHis: 1.06 ± 0.034
3.773AsnIle: 3.773 ± 0.07
3.568AsnLys: 3.568 ± 0.067
5.528AsnLeu: 5.528 ± 0.082
1.029AsnMet: 1.029 ± 0.038
3.218AsnAsn: 3.218 ± 0.091
3.527AsnPro: 3.527 ± 0.087
2.504AsnGln: 2.504 ± 0.052
2.28AsnArg: 2.28 ± 0.055
3.753AsnSer: 3.753 ± 0.087
3.178AsnThr: 3.178 ± 0.078
3.094AsnVal: 3.094 ± 0.074
0.737AsnTrp: 0.737 ± 0.033
2.483AsnTyr: 2.483 ± 0.061
0.0AsnXaa: 0.0 ± 0.0
Pro
2.429ProAla: 2.429 ± 0.056
0.384ProCys: 0.384 ± 0.022
2.457ProAsp: 2.457 ± 0.063
3.203ProGlu: 3.203 ± 0.063
2.1ProPhe: 2.1 ± 0.049
2.828ProGly: 2.828 ± 0.08
0.691ProHis: 0.691 ± 0.03
2.812ProIle: 2.812 ± 0.062
2.667ProLys: 2.667 ± 0.06
3.213ProLeu: 3.213 ± 0.063
0.661ProMet: 0.661 ± 0.027
2.764ProAsn: 2.764 ± 0.068
1.112ProPro: 1.112 ± 0.053
1.291ProGln: 1.291 ± 0.038
1.185ProArg: 1.185 ± 0.036
2.743ProSer: 2.743 ± 0.07
2.216ProThr: 2.216 ± 0.065
2.769ProVal: 2.769 ± 0.062
0.413ProTrp: 0.413 ± 0.023
1.468ProTyr: 1.468 ± 0.055
0.0ProXaa: 0.0 ± 0.0
Gln
2.143GlnAla: 2.143 ± 0.053
0.269GlnCys: 0.269 ± 0.017
1.814GlnAsp: 1.814 ± 0.043
2.456GlnGlu: 2.456 ± 0.058
1.835GlnPhe: 1.835 ± 0.052
2.105GlnGly: 2.105 ± 0.05
0.668GlnHis: 0.668 ± 0.031
2.682GlnIle: 2.682 ± 0.062
2.469GlnLys: 2.469 ± 0.062
3.577GlnLeu: 3.577 ± 0.074
0.73GlnMet: 0.73 ± 0.031
2.018GlnAsn: 2.018 ± 0.052
1.251GlnPro: 1.251 ± 0.042
1.447GlnGln: 1.447 ± 0.05
1.355GlnArg: 1.355 ± 0.036
2.2GlnSer: 2.2 ± 0.05
1.657GlnThr: 1.657 ± 0.054
2.286GlnVal: 2.286 ± 0.057
0.506GlnTrp: 0.506 ± 0.028
1.303GlnTyr: 1.303 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.315ArgAla: 2.315 ± 0.057
0.322ArgCys: 0.322 ± 0.018
1.965ArgAsp: 1.965 ± 0.052
2.447ArgGlu: 2.447 ± 0.069
2.144ArgPhe: 2.144 ± 0.051
2.243ArgGly: 2.243 ± 0.054
0.612ArgHis: 0.612 ± 0.026
3.17ArgIle: 3.17 ± 0.061
2.863ArgLys: 2.863 ± 0.075
3.658ArgLeu: 3.658 ± 0.072
0.899ArgMet: 0.899 ± 0.031
2.181ArgAsn: 2.181 ± 0.058
1.257ArgPro: 1.257 ± 0.042
1.154ArgGln: 1.154 ± 0.037
1.486ArgArg: 1.486 ± 0.047
2.22ArgSer: 2.22 ± 0.056
1.774ArgThr: 1.774 ± 0.047
2.728ArgVal: 2.728 ± 0.056
0.484ArgTrp: 0.484 ± 0.023
1.529ArgTyr: 1.529 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
4.36SerAla: 4.36 ± 0.091
0.734SerCys: 0.734 ± 0.033
3.698SerAsp: 3.698 ± 0.074
4.218SerGlu: 4.218 ± 0.079
3.906SerPhe: 3.906 ± 0.075
5.616SerGly: 5.616 ± 0.101
1.009SerHis: 1.009 ± 0.035
4.899SerIle: 4.899 ± 0.089
4.478SerLys: 4.478 ± 0.078
6.26SerLeu: 6.26 ± 0.1
1.199SerMet: 1.199 ± 0.039
3.776SerAsn: 3.776 ± 0.082
2.493SerPro: 2.493 ± 0.061
2.052SerGln: 2.052 ± 0.045
2.271SerArg: 2.271 ± 0.057
4.772SerSer: 4.772 ± 0.108
3.81SerThr: 3.81 ± 0.086
4.338SerVal: 4.338 ± 0.093
0.865SerTrp: 0.865 ± 0.034
2.825SerTyr: 2.825 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
3.626ThrAla: 3.626 ± 0.096
0.509ThrCys: 0.509 ± 0.027
3.041ThrAsp: 3.041 ± 0.084
3.234ThrGlu: 3.234 ± 0.063
2.635ThrPhe: 2.635 ± 0.072
4.327ThrGly: 4.327 ± 0.105
0.939ThrHis: 0.939 ± 0.034
3.998ThrIle: 3.998 ± 0.085
2.936ThrLys: 2.936 ± 0.059
5.259ThrLeu: 5.259 ± 0.09
0.822ThrMet: 0.822 ± 0.029
2.688ThrAsn: 2.688 ± 0.07
2.59ThrPro: 2.59 ± 0.069
1.846ThrGln: 1.846 ± 0.048
1.827ThrArg: 1.827 ± 0.045
3.336ThrSer: 3.336 ± 0.087
3.179ThrThr: 3.179 ± 0.094
4.107ThrVal: 4.107 ± 0.13
0.668ThrTrp: 0.668 ± 0.034
2.249ThrTyr: 2.249 ± 0.066
0.0ThrXaa: 0.0 ± 0.0
Val
4.381ValAla: 4.381 ± 0.081
0.745ValCys: 0.745 ± 0.036
4.044ValAsp: 4.044 ± 0.082
4.418ValGlu: 4.418 ± 0.071
3.429ValPhe: 3.429 ± 0.07
4.259ValGly: 4.259 ± 0.074
1.047ValHis: 1.047 ± 0.039
4.436ValIle: 4.436 ± 0.073
4.399ValLys: 4.399 ± 0.075
6.026ValLeu: 6.026 ± 0.091
1.194ValMet: 1.194 ± 0.036
3.836ValAsn: 3.836 ± 0.083
2.393ValPro: 2.393 ± 0.061
1.885ValGln: 1.885 ± 0.047
2.285ValArg: 2.285 ± 0.048
4.538ValSer: 4.538 ± 0.089
3.466ValThr: 3.466 ± 0.113
4.626ValVal: 4.626 ± 0.098
0.682ValTrp: 0.682 ± 0.025
2.362ValTyr: 2.362 ± 0.054
0.0ValXaa: 0.0 ± 0.0
Trp
0.65TrpAla: 0.65 ± 0.03
0.12TrpCys: 0.12 ± 0.011
0.706TrpAsp: 0.706 ± 0.026
0.802TrpGlu: 0.802 ± 0.03
0.623TrpPhe: 0.623 ± 0.027
0.626TrpGly: 0.626 ± 0.027
0.207TrpHis: 0.207 ± 0.016
0.894TrpIle: 0.894 ± 0.036
0.815TrpLys: 0.815 ± 0.037
1.054TrpLeu: 1.054 ± 0.042
0.309TrpMet: 0.309 ± 0.02
0.762TrpAsn: 0.762 ± 0.037
0.299TrpPro: 0.299 ± 0.016
0.409TrpGln: 0.409 ± 0.026
0.441TrpArg: 0.441 ± 0.023
0.761TrpSer: 0.761 ± 0.04
0.61TrpThr: 0.61 ± 0.029
0.798TrpVal: 0.798 ± 0.032
0.136TrpTrp: 0.136 ± 0.013
0.484TrpTyr: 0.484 ± 0.029
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.28TyrAla: 2.28 ± 0.054
0.44TyrCys: 0.44 ± 0.026
2.047TyrAsp: 2.047 ± 0.047
2.12TyrGlu: 2.12 ± 0.055
2.287TyrPhe: 2.287 ± 0.051
2.641TyrGly: 2.641 ± 0.061
0.835TyrHis: 0.835 ± 0.03
2.232TyrIle: 2.232 ± 0.051
2.443TyrLys: 2.443 ± 0.049
3.692TyrLeu: 3.692 ± 0.071
0.599TyrMet: 0.599 ± 0.026
2.234TyrAsn: 2.234 ± 0.062
1.714TyrPro: 1.714 ± 0.04
1.765TyrGln: 1.765 ± 0.053
1.844TyrArg: 1.844 ± 0.051
2.642TyrSer: 2.642 ± 0.058
2.277TyrThr: 2.277 ± 0.07
1.934TyrVal: 1.934 ± 0.052
0.524TyrTrp: 0.524 ± 0.025
1.703TyrTyr: 1.703 ± 0.047
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2382 proteins (906267 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski