Amino acid dipepetide frequency for Sida yellow vein Madurai virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.573AlaAla: 2.573 ± 1.61
0.0AlaCys: 0.0 ± 0.0
0.858AlaAsp: 0.858 ± 0.934
0.0AlaGlu: 0.0 ± 0.0
1.715AlaPhe: 1.715 ± 1.084
1.715AlaGly: 1.715 ± 1.223
2.573AlaHis: 2.573 ± 1.937
5.146AlaIle: 5.146 ± 1.918
3.431AlaLys: 3.431 ± 1.022
2.573AlaLeu: 2.573 ± 0.926
0.858AlaMet: 0.858 ± 0.747
0.858AlaAsn: 0.858 ± 0.611
1.715AlaPro: 1.715 ± 0.791
3.431AlaGln: 3.431 ± 1.323
3.431AlaArg: 3.431 ± 2.082
2.573AlaSer: 2.573 ± 1.131
2.573AlaThr: 2.573 ± 2.048
3.431AlaVal: 3.431 ± 1.946
0.0AlaTrp: 0.0 ± 0.0
0.858AlaTyr: 0.858 ± 0.611
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.858CysGlu: 0.858 ± 0.747
0.858CysPhe: 0.858 ± 0.934
1.715CysGly: 1.715 ± 0.958
1.715CysHis: 1.715 ± 1.307
1.715CysIle: 1.715 ± 2.024
2.573CysLys: 2.573 ± 1.2
1.715CysLeu: 1.715 ± 1.178
0.858CysMet: 0.858 ± 0.747
1.715CysAsn: 1.715 ± 1.869
0.858CysPro: 0.858 ± 0.611
0.858CysGln: 0.858 ± 0.611
0.0CysArg: 0.0 ± 0.0
2.573CysSer: 2.573 ± 1.227
3.431CysThr: 3.431 ± 1.54
1.715CysVal: 1.715 ± 0.791
0.0CysTrp: 0.0 ± 0.0
0.858CysTyr: 0.858 ± 0.747
0.0CysXaa: 0.0 ± 0.0
Asp
1.715AspAla: 1.715 ± 0.791
0.858AspCys: 0.858 ± 0.983
0.858AspAsp: 0.858 ± 0.747
1.715AspGlu: 1.715 ± 1.108
1.715AspPhe: 1.715 ± 1.08
2.573AspGly: 2.573 ± 1.341
0.0AspHis: 0.0 ± 0.0
0.858AspIle: 0.858 ± 0.747
0.858AspLys: 0.858 ± 0.611
4.288AspLeu: 4.288 ± 3.034
0.858AspMet: 0.858 ± 0.934
1.715AspAsn: 1.715 ± 1.108
2.573AspPro: 2.573 ± 1.559
0.858AspGln: 0.858 ± 1.096
1.715AspArg: 1.715 ± 1.084
4.288AspSer: 4.288 ± 2.331
0.858AspThr: 0.858 ± 0.611
2.573AspVal: 2.573 ± 1.413
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
0.858GluAla: 0.858 ± 0.611
0.858GluCys: 0.858 ± 1.012
2.573GluAsp: 2.573 ± 2.294
3.431GluGlu: 3.431 ± 1.541
0.858GluPhe: 0.858 ± 1.012
6.003GluGly: 6.003 ± 1.683
0.858GluHis: 0.858 ± 0.983
2.573GluIle: 2.573 ± 1.14
0.0GluLys: 0.0 ± 0.0
1.715GluLeu: 1.715 ± 1.183
0.0GluMet: 0.0 ± 0.0
3.431GluAsn: 3.431 ± 1.153
1.715GluPro: 1.715 ± 0.791
0.0GluGln: 0.0 ± 0.0
3.431GluArg: 3.431 ± 1.541
2.573GluSer: 2.573 ± 1.326
2.573GluThr: 2.573 ± 1.335
2.573GluVal: 2.573 ± 1.956
0.858GluTrp: 0.858 ± 0.611
0.858GluTyr: 0.858 ± 0.934
0.0GluXaa: 0.0 ± 0.0
Phe
0.858PheAla: 0.858 ± 0.611
0.858PheCys: 0.858 ± 0.747
2.573PheAsp: 2.573 ± 1.413
0.858PheGlu: 0.858 ± 0.611
0.858PhePhe: 0.858 ± 0.611
0.0PheGly: 0.0 ± 0.0
1.715PheHis: 1.715 ± 0.958
2.573PheIle: 2.573 ± 1.265
4.288PheLys: 4.288 ± 1.698
4.288PheLeu: 4.288 ± 1.674
0.858PheMet: 0.858 ± 0.747
2.573PheAsn: 2.573 ± 1.413
2.573PhePro: 2.573 ± 1.937
2.573PheGln: 2.573 ± 0.934
6.861PheArg: 6.861 ± 3.367
1.715PheSer: 1.715 ± 0.791
4.288PheThr: 4.288 ± 1.774
0.858PheVal: 0.858 ± 0.747
0.858PheTrp: 0.858 ± 0.747
2.573PheTyr: 2.573 ± 1.413
0.0PheXaa: 0.0 ± 0.0
Gly
0.858GlyAla: 0.858 ± 0.611
2.573GlyCys: 2.573 ± 1.308
1.715GlyAsp: 1.715 ± 0.958
4.288GlyGlu: 4.288 ± 1.398
5.146GlyPhe: 5.146 ± 0.753
2.573GlyGly: 2.573 ± 1.272
4.288GlyHis: 4.288 ± 0.99
1.715GlyIle: 1.715 ± 0.958
5.146GlyLys: 5.146 ± 2.374
3.431GlyLeu: 3.431 ± 0.938
1.715GlyMet: 1.715 ± 1.113
3.431GlyAsn: 3.431 ± 2.353
6.003GlyPro: 6.003 ± 2.387
2.573GlyGln: 2.573 ± 1.129
4.288GlyArg: 4.288 ± 2.293
4.288GlySer: 4.288 ± 2.175
3.431GlyThr: 3.431 ± 2.117
1.715GlyVal: 1.715 ± 1.307
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.858HisCys: 0.858 ± 0.983
0.0HisAsp: 0.0 ± 0.0
0.858HisGlu: 0.858 ± 0.611
2.573HisPhe: 2.573 ± 1.341
2.573HisGly: 2.573 ± 2.176
1.715HisHis: 1.715 ± 1.307
1.715HisIle: 1.715 ± 1.183
1.715HisLys: 1.715 ± 1.869
1.715HisLeu: 1.715 ± 1.223
0.858HisMet: 0.858 ± 0.747
3.431HisAsn: 3.431 ± 2.613
1.715HisPro: 1.715 ± 0.929
1.715HisGln: 1.715 ± 1.384
2.573HisArg: 2.573 ± 1.477
0.0HisSer: 0.0 ± 0.0
0.858HisThr: 0.858 ± 0.747
3.431HisVal: 3.431 ± 0.938
2.573HisTrp: 2.573 ± 1.14
0.858HisTyr: 0.858 ± 0.934
0.0HisXaa: 0.0 ± 0.0
Ile
2.573IleAla: 2.573 ± 1.248
1.715IleCys: 1.715 ± 1.178
2.573IleAsp: 2.573 ± 1.2
1.715IleGlu: 1.715 ± 2.024
1.715IlePhe: 1.715 ± 0.958
1.715IleGly: 1.715 ± 0.791
1.715IleHis: 1.715 ± 1.307
3.431IleIle: 3.431 ± 2.446
5.146IleLys: 5.146 ± 1.692
3.431IleLeu: 3.431 ± 1.921
1.715IleMet: 1.715 ± 0.791
0.858IleAsn: 0.858 ± 0.747
4.288IlePro: 4.288 ± 2.306
5.146IleGln: 5.146 ± 2.881
3.431IleArg: 3.431 ± 1.461
5.146IleSer: 5.146 ± 2.263
2.573IleThr: 2.573 ± 2.803
2.573IleVal: 2.573 ± 1.61
2.573IleTrp: 2.573 ± 0.926
4.288IleTyr: 4.288 ± 1.571
0.0IleXaa: 0.0 ± 0.0
Lys
4.288LysAla: 4.288 ± 1.262
3.431LysCys: 3.431 ± 1.757
1.715LysAsp: 1.715 ± 0.791
1.715LysGlu: 1.715 ± 1.223
0.858LysPhe: 0.858 ± 0.611
0.858LysGly: 0.858 ± 0.747
0.0LysHis: 0.0 ± 0.0
4.288LysIle: 4.288 ± 2.192
0.858LysLys: 0.858 ± 0.611
0.858LysLeu: 0.858 ± 0.611
0.0LysMet: 0.0 ± 0.0
2.573LysAsn: 2.573 ± 1.2
0.858LysPro: 0.858 ± 0.747
0.858LysGln: 0.858 ± 0.934
5.146LysArg: 5.146 ± 1.868
6.861LysSer: 6.861 ± 2.376
0.858LysThr: 0.858 ± 1.012
6.003LysVal: 6.003 ± 2.629
0.0LysTrp: 0.0 ± 0.0
3.431LysTyr: 3.431 ± 1.819
0.0LysXaa: 0.0 ± 0.0
Leu
2.573LeuAla: 2.573 ± 2.176
1.715LeuCys: 1.715 ± 1.08
3.431LeuAsp: 3.431 ± 2.044
4.288LeuGlu: 4.288 ± 1.95
1.715LeuPhe: 1.715 ± 0.791
5.146LeuGly: 5.146 ± 1.854
3.431LeuHis: 3.431 ± 1.858
5.146LeuIle: 5.146 ± 2.155
4.288LeuLys: 4.288 ± 2.359
12.864LeuLeu: 12.864 ± 3.602
3.431LeuMet: 3.431 ± 1.781
2.573LeuAsn: 2.573 ± 1.477
4.288LeuPro: 4.288 ± 3.554
5.146LeuGln: 5.146 ± 2.129
6.003LeuArg: 6.003 ± 1.659
8.576LeuSer: 8.576 ± 2.09
6.861LeuThr: 6.861 ± 2.475
2.573LeuVal: 2.573 ± 1.937
2.573LeuTrp: 2.573 ± 1.834
0.858LeuTyr: 0.858 ± 0.934
0.0LeuXaa: 0.0 ± 0.0
Met
3.431MetAla: 3.431 ± 1.684
0.0MetCys: 0.0 ± 0.0
0.858MetAsp: 0.858 ± 0.934
0.0MetGlu: 0.0 ± 0.0
3.431MetPhe: 3.431 ± 1.394
1.715MetGly: 1.715 ± 1.178
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
6.003MetLeu: 6.003 ± 2.98
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.858MetPro: 0.858 ± 0.747
2.573MetGln: 2.573 ± 1.558
2.573MetArg: 2.573 ± 1.614
2.573MetSer: 2.573 ± 1.14
0.858MetThr: 0.858 ± 0.611
0.0MetVal: 0.0 ± 0.0
0.858MetTrp: 0.858 ± 1.012
1.715MetTyr: 1.715 ± 1.495
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.858AsnCys: 0.858 ± 0.983
0.858AsnAsp: 0.858 ± 0.611
1.715AsnGlu: 1.715 ± 1.08
1.715AsnPhe: 1.715 ± 0.791
2.573AsnGly: 2.573 ± 1.439
2.573AsnHis: 2.573 ± 1.308
2.573AsnIle: 2.573 ± 1.2
2.573AsnLys: 2.573 ± 0.926
4.288AsnLeu: 4.288 ± 1.509
0.858AsnMet: 0.858 ± 0.747
0.0AsnAsn: 0.0 ± 0.0
0.0AsnPro: 0.0 ± 0.0
1.715AsnGln: 1.715 ± 1.183
1.715AsnArg: 1.715 ± 0.791
5.146AsnSer: 5.146 ± 3.051
2.573AsnThr: 2.573 ± 1.131
1.715AsnVal: 1.715 ± 1.495
0.0AsnTrp: 0.0 ± 0.0
2.573AsnTyr: 2.573 ± 1.265
0.0AsnXaa: 0.0 ± 0.0
Pro
2.573ProAla: 2.573 ± 1.413
1.715ProCys: 1.715 ± 1.08
2.573ProAsp: 2.573 ± 1.326
2.573ProGlu: 2.573 ± 1.326
0.0ProPhe: 0.0 ± 0.0
3.431ProGly: 3.431 ± 1.135
0.858ProHis: 0.858 ± 0.611
4.288ProIle: 4.288 ± 1.738
1.715ProLys: 1.715 ± 0.791
7.719ProLeu: 7.719 ± 2.402
0.858ProMet: 0.858 ± 0.747
1.715ProAsn: 1.715 ± 1.223
1.715ProPro: 1.715 ± 0.929
5.146ProGln: 5.146 ± 1.949
6.861ProArg: 6.861 ± 1.367
6.861ProSer: 6.861 ± 1.833
6.003ProThr: 6.003 ± 0.772
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.288GlnAla: 4.288 ± 1.862
1.715GlnCys: 1.715 ± 1.084
0.858GlnAsp: 0.858 ± 0.983
1.715GlnGlu: 1.715 ± 1.394
2.573GlnPhe: 2.573 ± 1.341
3.431GlnGly: 3.431 ± 2.037
0.858GlnHis: 0.858 ± 1.096
2.573GlnIle: 2.573 ± 1.265
0.858GlnLys: 0.858 ± 0.983
2.573GlnLeu: 2.573 ± 1.309
1.715GlnMet: 1.715 ± 1.25
1.715GlnAsn: 1.715 ± 1.223
3.431GlnPro: 3.431 ± 2.613
3.431GlnGln: 3.431 ± 1.386
4.288GlnArg: 4.288 ± 2.305
4.288GlnSer: 4.288 ± 1.337
6.003GlnThr: 6.003 ± 3.384
3.431GlnVal: 3.431 ± 1.42
0.0GlnTrp: 0.0 ± 0.0
0.858GlnTyr: 0.858 ± 0.611
0.0GlnXaa: 0.0 ± 0.0
Arg
1.715ArgAla: 1.715 ± 1.293
1.715ArgCys: 1.715 ± 1.223
0.858ArgAsp: 0.858 ± 0.747
1.715ArgGlu: 1.715 ± 1.183
8.576ArgPhe: 8.576 ± 2.582
9.434ArgGly: 9.434 ± 3.182
0.858ArgHis: 0.858 ± 0.934
5.146ArgIle: 5.146 ± 2.65
4.288ArgLys: 4.288 ± 1.737
6.003ArgLeu: 6.003 ± 1.702
2.573ArgMet: 2.573 ± 1.413
0.0ArgAsn: 0.0 ± 0.0
6.003ArgPro: 6.003 ± 2.629
3.431ArgGln: 3.431 ± 2.155
14.58ArgArg: 14.58 ± 5.685
10.292ArgSer: 10.292 ± 2.727
5.146ArgThr: 5.146 ± 2.666
5.146ArgVal: 5.146 ± 2.745
0.858ArgTrp: 0.858 ± 0.747
3.431ArgTyr: 3.431 ± 2.037
0.0ArgXaa: 0.0 ± 0.0
Ser
6.861SerAla: 6.861 ± 2.156
0.858SerCys: 0.858 ± 0.934
4.288SerAsp: 4.288 ± 1.989
1.715SerGlu: 1.715 ± 1.108
2.573SerPhe: 2.573 ± 0.934
3.431SerGly: 3.431 ± 1.279
2.573SerHis: 2.573 ± 1.335
5.146SerIle: 5.146 ± 2.102
1.715SerLys: 1.715 ± 1.223
8.576SerLeu: 8.576 ± 3.91
3.431SerMet: 3.431 ± 1.605
2.573SerAsn: 2.573 ± 1.439
8.576SerPro: 8.576 ± 2.179
3.431SerGln: 3.431 ± 1.75
6.003SerArg: 6.003 ± 2.341
15.437SerSer: 15.437 ± 3.778
11.149SerThr: 11.149 ± 4.701
5.146SerVal: 5.146 ± 1.631
2.573SerTrp: 2.573 ± 1.265
2.573SerTyr: 2.573 ± 1.263
0.0SerXaa: 0.0 ± 0.0
Thr
4.288ThrAla: 4.288 ± 0.99
1.715ThrCys: 1.715 ± 1.334
0.858ThrAsp: 0.858 ± 1.096
2.573ThrGlu: 2.573 ± 2.294
2.573ThrPhe: 2.573 ± 2.026
5.146ThrGly: 5.146 ± 1.147
1.715ThrHis: 1.715 ± 1.108
2.573ThrIle: 2.573 ± 1.558
0.858ThrLys: 0.858 ± 0.611
5.146ThrLeu: 5.146 ± 2.352
1.715ThrMet: 1.715 ± 1.297
4.288ThrAsn: 4.288 ± 1.447
4.288ThrPro: 4.288 ± 2.096
4.288ThrGln: 4.288 ± 1.679
6.861ThrArg: 6.861 ± 2.59
9.434ThrSer: 9.434 ± 3.24
7.719ThrThr: 7.719 ± 2.718
5.146ThrVal: 5.146 ± 1.631
3.431ThrTrp: 3.431 ± 1.559
1.715ThrTyr: 1.715 ± 0.958
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.858ValCys: 0.858 ± 0.611
0.858ValAsp: 0.858 ± 0.983
5.146ValGlu: 5.146 ± 1.707
1.715ValPhe: 1.715 ± 1.495
3.431ValGly: 3.431 ± 1.404
3.431ValHis: 3.431 ± 1.946
2.573ValIle: 2.573 ± 2.242
4.288ValLys: 4.288 ± 1.926
6.861ValLeu: 6.861 ± 2.445
1.715ValMet: 1.715 ± 1.428
1.715ValAsn: 1.715 ± 1.869
1.715ValPro: 1.715 ± 1.108
3.431ValGln: 3.431 ± 1.921
6.003ValArg: 6.003 ± 2.534
2.573ValSer: 2.573 ± 1.272
3.431ValThr: 3.431 ± 1.153
1.715ValVal: 1.715 ± 0.791
0.858ValTrp: 0.858 ± 1.012
1.715ValTyr: 1.715 ± 1.08
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.715TrpAsp: 1.715 ± 1.293
0.0TrpGlu: 0.0 ± 0.0
0.858TrpPhe: 0.858 ± 1.012
1.715TrpGly: 1.715 ± 1.223
0.858TrpHis: 0.858 ± 0.747
0.858TrpIle: 0.858 ± 0.747
0.0TrpLys: 0.0 ± 0.0
0.858TrpLeu: 0.858 ± 0.611
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.573TrpArg: 2.573 ± 1.341
0.858TrpSer: 0.858 ± 1.096
4.288TrpThr: 4.288 ± 0.99
4.288TrpVal: 4.288 ± 1.622
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.858TyrAla: 0.858 ± 0.611
1.715TyrCys: 1.715 ± 0.791
0.858TyrAsp: 0.858 ± 0.747
0.858TyrGlu: 0.858 ± 0.747
2.573TyrPhe: 2.573 ± 0.926
0.858TyrGly: 0.858 ± 0.934
0.0TyrHis: 0.0 ± 0.0
3.431TyrIle: 3.431 ± 1.757
0.858TyrLys: 0.858 ± 0.611
2.573TyrLeu: 2.573 ± 1.14
2.573TyrMet: 2.573 ± 1.937
0.858TyrAsn: 0.858 ± 0.611
3.431TyrPro: 3.431 ± 2.446
0.0TyrGln: 0.0 ± 0.0
3.431TyrArg: 3.431 ± 2.258
2.573TyrSer: 2.573 ± 1.515
0.858TyrThr: 0.858 ± 0.611
0.0TyrVal: 0.0 ± 0.0
0.858TyrTrp: 0.858 ± 0.934
0.858TyrTyr: 0.858 ± 0.983
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1167 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski