Amino acid dipepetide frequency for Microviridae sp. ctYqV29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.56AlaAla: 5.56 ± 1.416
0.0AlaCys: 0.0 ± 0.0
7.943AlaAsp: 7.943 ± 1.508
3.971AlaGlu: 3.971 ± 0.866
1.589AlaPhe: 1.589 ± 1.251
10.326AlaGly: 10.326 ± 4.702
0.794AlaHis: 0.794 ± 0.525
3.971AlaIle: 3.971 ± 1.229
2.383AlaLys: 2.383 ± 1.417
9.531AlaLeu: 9.531 ± 0.721
2.383AlaMet: 2.383 ± 0.941
1.589AlaAsn: 1.589 ± 0.653
3.177AlaPro: 3.177 ± 1.959
3.971AlaGln: 3.971 ± 1.04
8.737AlaArg: 8.737 ± 3.081
7.149AlaSer: 7.149 ± 1.361
2.383AlaThr: 2.383 ± 1.133
7.149AlaVal: 7.149 ± 0.517
0.794AlaTrp: 0.794 ± 0.72
1.589AlaTyr: 1.589 ± 0.833
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.589CysCys: 1.589 ± 1.292
1.589CysAsp: 1.589 ± 0.603
1.589CysGlu: 1.589 ± 1.292
0.0CysPhe: 0.0 ± 0.0
3.177CysGly: 3.177 ± 1.744
0.0CysHis: 0.0 ± 0.0
1.589CysIle: 1.589 ± 1.292
0.794CysLys: 0.794 ± 0.646
1.589CysLeu: 1.589 ± 0.603
0.794CysMet: 0.794 ± 0.862
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.794CysArg: 0.794 ± 0.646
2.383CysSer: 2.383 ± 1.133
0.794CysThr: 0.794 ± 0.646
1.589CysVal: 1.589 ± 1.019
0.0CysTrp: 0.0 ± 0.0
0.794CysTyr: 0.794 ± 0.646
0.0CysXaa: 0.0 ± 0.0
Asp
7.943AspAla: 7.943 ± 2.571
0.794AspCys: 0.794 ± 0.646
2.383AspAsp: 2.383 ± 1.417
2.383AspGlu: 2.383 ± 1.133
3.971AspPhe: 3.971 ± 2.627
4.766AspGly: 4.766 ± 1.041
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
4.766AspLeu: 4.766 ± 1.669
0.794AspMet: 0.794 ± 0.525
0.794AspAsn: 0.794 ± 1.113
3.177AspPro: 3.177 ± 1.987
0.794AspGln: 0.794 ± 0.525
2.383AspArg: 2.383 ± 1.27
0.794AspSer: 0.794 ± 0.72
6.354AspThr: 6.354 ± 2.052
3.971AspVal: 3.971 ± 1.696
1.589AspTrp: 1.589 ± 0.833
3.177AspTyr: 3.177 ± 1.378
0.0AspXaa: 0.0 ± 0.0
Glu
6.354GluAla: 6.354 ± 2.205
0.0GluCys: 0.0 ± 0.0
3.971GluAsp: 3.971 ± 1.874
3.177GluGlu: 3.177 ± 1.205
2.383GluPhe: 2.383 ± 1.305
2.383GluGly: 2.383 ± 0.928
0.794GluHis: 0.794 ± 0.525
0.0GluIle: 0.0 ± 0.0
0.794GluLys: 0.794 ± 0.525
3.971GluLeu: 3.971 ± 1.04
1.589GluMet: 1.589 ± 1.193
0.794GluAsn: 0.794 ± 0.72
1.589GluPro: 1.589 ± 1.292
1.589GluGln: 1.589 ± 0.603
3.177GluArg: 3.177 ± 1.377
3.177GluSer: 3.177 ± 1.103
1.589GluThr: 1.589 ± 0.653
7.149GluVal: 7.149 ± 2.64
0.794GluTrp: 0.794 ± 0.525
5.56GluTyr: 5.56 ± 1.416
0.0GluXaa: 0.0 ± 0.0
Phe
4.766PheAla: 4.766 ± 1.053
1.589PheCys: 1.589 ± 1.292
0.794PheAsp: 0.794 ± 0.646
0.794PheGlu: 0.794 ± 0.525
0.0PhePhe: 0.0 ± 0.0
3.971PheGly: 3.971 ± 1.04
0.0PheHis: 0.0 ± 0.0
2.383PheIle: 2.383 ± 1.576
0.794PheLys: 0.794 ± 1.041
1.589PheLeu: 1.589 ± 0.603
0.794PheMet: 0.794 ± 0.72
0.0PheAsn: 0.0 ± 0.0
0.794PhePro: 0.794 ± 0.525
0.0PheGln: 0.0 ± 0.0
3.177PheArg: 3.177 ± 1.393
2.383PheSer: 2.383 ± 2.068
1.589PheThr: 1.589 ± 0.653
0.794PheVal: 0.794 ± 0.525
1.589PheTrp: 1.589 ± 1.051
1.589PheTyr: 1.589 ± 1.292
0.0PheXaa: 0.0 ± 0.0
Gly
6.354GlyAla: 6.354 ± 1.64
0.0GlyCys: 0.0 ± 0.0
3.971GlyAsp: 3.971 ± 1.04
4.766GlyGlu: 4.766 ± 1.39
3.971GlyPhe: 3.971 ± 2.491
5.56GlyGly: 5.56 ± 2.304
2.383GlyHis: 2.383 ± 1.048
4.766GlyIle: 4.766 ± 1.041
4.766GlyLys: 4.766 ± 2.026
3.971GlyLeu: 3.971 ± 1.04
0.794GlyMet: 0.794 ± 0.72
1.589GlyAsn: 1.589 ± 1.051
3.971GlyPro: 3.971 ± 1.229
5.56GlyGln: 5.56 ± 2.289
11.12GlyArg: 11.12 ± 4.966
10.326GlySer: 10.326 ± 2.787
3.177GlyThr: 3.177 ± 1.514
4.766GlyVal: 4.766 ± 2.565
0.794GlyTrp: 0.794 ± 1.041
4.766GlyTyr: 4.766 ± 1.136
0.0GlyXaa: 0.0 ± 0.0
His
0.794HisAla: 0.794 ± 0.525
0.794HisCys: 0.794 ± 1.113
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
3.177HisGly: 3.177 ± 1.205
0.794HisHis: 0.794 ± 0.525
0.0HisIle: 0.0 ± 0.0
0.794HisLys: 0.794 ± 1.041
0.794HisLeu: 0.794 ± 0.646
0.794HisMet: 0.794 ± 0.525
0.0HisAsn: 0.0 ± 0.0
1.589HisPro: 1.589 ± 0.653
0.0HisGln: 0.0 ± 0.0
1.589HisArg: 1.589 ± 0.603
0.794HisSer: 0.794 ± 0.525
0.0HisThr: 0.0 ± 0.0
0.794HisVal: 0.794 ± 0.646
1.589HisTrp: 1.589 ± 1.051
0.794HisTyr: 0.794 ± 0.646
0.0HisXaa: 0.0 ± 0.0
Ile
3.177IleAla: 3.177 ± 1.103
0.794IleCys: 0.794 ± 0.646
1.589IleAsp: 1.589 ± 1.292
1.589IleGlu: 1.589 ± 1.051
2.383IlePhe: 2.383 ± 1.178
5.56IleGly: 5.56 ± 2.379
0.794IleHis: 0.794 ± 0.72
0.794IleIle: 0.794 ± 1.041
0.794IleLys: 0.794 ± 0.72
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.794IleAsn: 0.794 ± 0.646
1.589IlePro: 1.589 ± 1.44
3.971IleGln: 3.971 ± 1.532
2.383IleArg: 2.383 ± 0.974
3.177IleSer: 3.177 ± 1.514
3.971IleThr: 3.971 ± 1.21
0.794IleVal: 0.794 ± 1.113
0.794IleTrp: 0.794 ± 0.525
1.589IleTyr: 1.589 ± 1.051
0.0IleXaa: 0.0 ± 0.0
Lys
3.177LysAla: 3.177 ± 1.635
1.589LysCys: 1.589 ± 0.603
2.383LysAsp: 2.383 ± 0.52
3.177LysGlu: 3.177 ± 1.378
0.794LysPhe: 0.794 ± 0.525
6.354LysGly: 6.354 ± 1.682
1.589LysHis: 1.589 ± 0.603
1.589LysIle: 1.589 ± 1.232
4.766LysLys: 4.766 ± 2.646
3.177LysLeu: 3.177 ± 1.103
2.383LysMet: 2.383 ± 1.28
0.794LysAsn: 0.794 ± 0.646
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
7.149LysArg: 7.149 ± 2.997
3.177LysSer: 3.177 ± 3.162
0.794LysThr: 0.794 ± 0.525
5.56LysVal: 5.56 ± 2.684
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
3.177LeuAla: 3.177 ± 1.378
1.589LeuCys: 1.589 ± 1.292
5.56LeuAsp: 5.56 ± 2.925
3.177LeuGlu: 3.177 ± 1.635
1.589LeuPhe: 1.589 ± 0.833
11.12LeuGly: 11.12 ± 2.461
0.794LeuHis: 0.794 ± 0.525
2.383LeuIle: 2.383 ± 1.265
7.149LeuLys: 7.149 ± 2.441
7.149LeuLeu: 7.149 ± 1.733
1.589LeuMet: 1.589 ± 1.241
2.383LeuAsn: 2.383 ± 0.928
3.177LeuPro: 3.177 ± 0.633
8.737LeuGln: 8.737 ± 2.056
10.326LeuArg: 10.326 ± 3.544
5.56LeuSer: 5.56 ± 2.025
2.383LeuThr: 2.383 ± 1.133
3.177LeuVal: 3.177 ± 1.382
1.589LeuTrp: 1.589 ± 0.603
1.589LeuTyr: 1.589 ± 0.653
0.0LeuXaa: 0.0 ± 0.0
Met
2.383MetAla: 2.383 ± 1.178
0.0MetCys: 0.0 ± 0.0
1.589MetAsp: 1.589 ± 1.44
0.794MetGlu: 0.794 ± 0.646
0.0MetPhe: 0.0 ± 0.0
1.589MetGly: 1.589 ± 0.653
0.794MetHis: 0.794 ± 0.525
0.794MetIle: 0.794 ± 0.525
1.589MetLys: 1.589 ± 0.603
0.794MetLeu: 0.794 ± 0.646
0.794MetMet: 0.794 ± 0.83
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
5.56MetArg: 5.56 ± 1.135
1.589MetSer: 1.589 ± 0.833
0.794MetThr: 0.794 ± 0.646
1.589MetVal: 1.589 ± 1.043
1.589MetTrp: 1.589 ± 1.44
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.766AsnAla: 4.766 ± 1.522
1.589AsnCys: 1.589 ± 0.603
0.0AsnAsp: 0.0 ± 0.0
1.589AsnGlu: 1.589 ± 0.653
0.0AsnPhe: 0.0 ± 0.0
0.794AsnGly: 0.794 ± 0.525
0.0AsnHis: 0.0 ± 0.0
0.794AsnIle: 0.794 ± 0.525
0.794AsnLys: 0.794 ± 0.525
2.383AsnLeu: 2.383 ± 1.27
0.0AsnMet: 0.0 ± 0.0
2.383AsnAsn: 2.383 ± 1.576
1.589AsnPro: 1.589 ± 1.232
1.589AsnGln: 1.589 ± 1.44
6.354AsnArg: 6.354 ± 1.116
0.0AsnSer: 0.0 ± 0.0
0.794AsnThr: 0.794 ± 1.113
2.383AsnVal: 2.383 ± 1.016
0.0AsnTrp: 0.0 ± 0.0
1.589AsnTyr: 1.589 ± 1.043
0.0AsnXaa: 0.0 ± 0.0
Pro
3.177ProAla: 3.177 ± 0.965
1.589ProCys: 1.589 ± 0.603
0.0ProAsp: 0.0 ± 0.0
3.971ProGlu: 3.971 ± 1.286
0.794ProPhe: 0.794 ± 0.525
3.177ProGly: 3.177 ± 0.633
1.589ProHis: 1.589 ± 0.603
2.383ProIle: 2.383 ± 2.16
0.794ProLys: 0.794 ± 0.525
7.149ProLeu: 7.149 ± 1.922
1.589ProMet: 1.589 ± 0.833
2.383ProAsn: 2.383 ± 0.52
0.794ProPro: 0.794 ± 0.72
0.794ProGln: 0.794 ± 0.525
2.383ProArg: 2.383 ± 2.278
3.177ProSer: 3.177 ± 1.377
4.766ProThr: 4.766 ± 1.882
6.354ProVal: 6.354 ± 1.67
0.794ProTrp: 0.794 ± 0.525
0.794ProTyr: 0.794 ± 1.113
0.0ProXaa: 0.0 ± 0.0
Gln
3.971GlnAla: 3.971 ± 1.532
0.0GlnCys: 0.0 ± 0.0
3.177GlnAsp: 3.177 ± 1.026
3.177GlnGlu: 3.177 ± 1.305
0.794GlnPhe: 0.794 ± 0.525
2.383GlnGly: 2.383 ± 0.52
0.0GlnHis: 0.0 ± 0.0
1.589GlnIle: 1.589 ± 0.603
3.971GlnLys: 3.971 ± 0.988
1.589GlnLeu: 1.589 ± 1.44
0.0GlnMet: 0.0 ± 0.0
1.589GlnAsn: 1.589 ± 0.653
0.0GlnPro: 0.0 ± 0.0
1.589GlnGln: 1.589 ± 1.051
3.177GlnArg: 3.177 ± 1.151
5.56GlnSer: 5.56 ± 1.033
3.177GlnThr: 3.177 ± 1.305
3.177GlnVal: 3.177 ± 1.635
1.589GlnTrp: 1.589 ± 0.653
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.149ArgAla: 7.149 ± 2.975
2.383ArgCys: 2.383 ± 1.65
2.383ArgAsp: 2.383 ± 1.133
3.971ArgGlu: 3.971 ± 1.696
3.971ArgPhe: 3.971 ± 1.676
6.354ArgGly: 6.354 ± 5.063
1.589ArgHis: 1.589 ± 0.603
3.177ArgIle: 3.177 ± 1.433
5.56ArgLys: 5.56 ± 2.814
11.914ArgLeu: 11.914 ± 2.424
3.177ArgMet: 3.177 ± 1.703
2.383ArgAsn: 2.383 ± 0.52
7.149ArgPro: 7.149 ± 1.158
2.383ArgGln: 2.383 ± 1.683
13.503ArgArg: 13.503 ± 7.032
7.149ArgSer: 7.149 ± 1.255
5.56ArgThr: 5.56 ± 2.362
2.383ArgVal: 2.383 ± 1.133
0.794ArgTrp: 0.794 ± 0.646
7.149ArgTyr: 7.149 ± 2.635
0.0ArgXaa: 0.0 ± 0.0
Ser
4.766SerAla: 4.766 ± 1.041
3.177SerCys: 3.177 ± 1.205
3.177SerAsp: 3.177 ± 1.514
5.56SerGlu: 5.56 ± 1.221
2.383SerPhe: 2.383 ± 1.133
3.971SerGly: 3.971 ± 1.21
0.0SerHis: 0.0 ± 0.0
1.589SerIle: 1.589 ± 0.603
5.56SerLys: 5.56 ± 4.106
5.56SerLeu: 5.56 ± 1.592
1.589SerMet: 1.589 ± 1.051
4.766SerAsn: 4.766 ± 1.853
8.737SerPro: 8.737 ± 2.454
1.589SerGln: 1.589 ± 0.833
3.971SerArg: 3.971 ± 0.866
5.56SerSer: 5.56 ± 2.159
1.589SerThr: 1.589 ± 1.051
8.737SerVal: 8.737 ± 1.979
0.794SerTrp: 0.794 ± 0.525
2.383SerTyr: 2.383 ± 0.974
0.0SerXaa: 0.0 ± 0.0
Thr
4.766ThrAla: 4.766 ± 1.136
0.0ThrCys: 0.0 ± 0.0
3.177ThrAsp: 3.177 ± 1.377
1.589ThrGlu: 1.589 ± 1.051
1.589ThrPhe: 1.589 ± 1.051
3.971ThrGly: 3.971 ± 1.532
0.794ThrHis: 0.794 ± 0.646
4.766ThrIle: 4.766 ± 3.152
1.589ThrLys: 1.589 ± 0.833
1.589ThrLeu: 1.589 ± 1.251
0.794ThrMet: 0.794 ± 0.72
0.0ThrAsn: 0.0 ± 0.0
3.177ThrPro: 3.177 ± 1.377
2.383ThrGln: 2.383 ± 1.016
0.794ThrArg: 0.794 ± 1.113
4.766ThrSer: 4.766 ± 1.34
3.971ThrThr: 3.971 ± 1.21
4.766ThrVal: 4.766 ± 0.746
1.589ThrTrp: 1.589 ± 0.603
1.589ThrTyr: 1.589 ± 0.833
0.0ThrXaa: 0.0 ± 0.0
Val
7.149ValAla: 7.149 ± 2.997
1.589ValCys: 1.589 ± 1.292
5.56ValAsp: 5.56 ± 1.304
1.589ValGlu: 1.589 ± 0.603
2.383ValPhe: 2.383 ± 0.928
3.177ValGly: 3.177 ± 2.102
0.794ValHis: 0.794 ± 1.113
0.794ValIle: 0.794 ± 1.113
3.971ValLys: 3.971 ± 1.04
10.326ValLeu: 10.326 ± 1.29
0.794ValMet: 0.794 ± 0.525
3.177ValAsn: 3.177 ± 3.162
7.149ValPro: 7.149 ± 2.784
2.383ValGln: 2.383 ± 0.52
7.149ValArg: 7.149 ± 3.677
6.354ValSer: 6.354 ± 1.675
2.383ValThr: 2.383 ± 1.27
1.589ValVal: 1.589 ± 1.292
0.794ValTrp: 0.794 ± 0.525
1.589ValTyr: 1.589 ± 1.051
0.0ValXaa: 0.0 ± 0.0
Trp
0.794TrpAla: 0.794 ± 0.72
0.794TrpCys: 0.794 ± 0.525
0.794TrpAsp: 0.794 ± 0.72
3.177TrpGlu: 3.177 ± 1.378
0.0TrpPhe: 0.0 ± 0.0
0.794TrpGly: 0.794 ± 0.646
0.794TrpHis: 0.794 ± 0.525
0.794TrpIle: 0.794 ± 1.041
0.794TrpLys: 0.794 ± 0.72
0.794TrpLeu: 0.794 ± 0.646
0.0TrpMet: 0.0 ± 0.0
3.177TrpAsn: 3.177 ± 1.305
0.0TrpPro: 0.0 ± 0.0
0.794TrpGln: 0.794 ± 0.525
1.589TrpArg: 1.589 ± 0.603
0.794TrpSer: 0.794 ± 0.525
0.794TrpThr: 0.794 ± 0.646
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.383TrpTyr: 2.383 ± 0.941
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.766TyrAla: 4.766 ± 1.136
0.0TyrCys: 0.0 ± 0.0
0.794TyrAsp: 0.794 ± 0.525
0.794TyrGlu: 0.794 ± 0.525
0.794TyrPhe: 0.794 ± 0.525
4.766TyrGly: 4.766 ± 1.785
0.794TyrHis: 0.794 ± 0.646
2.383TyrIle: 2.383 ± 0.928
0.794TyrLys: 0.794 ± 0.525
5.56TyrLeu: 5.56 ± 1.146
0.794TyrMet: 0.794 ± 0.527
0.794TyrAsn: 0.794 ± 0.72
0.794TyrPro: 0.794 ± 0.646
2.383TyrGln: 2.383 ± 1.115
4.766TyrArg: 4.766 ± 1.522
1.589TyrSer: 1.589 ± 0.833
0.794TyrThr: 0.794 ± 0.525
3.971TyrVal: 3.971 ± 1.275
1.589TyrTrp: 1.589 ± 1.44
0.794TyrTyr: 0.794 ± 0.72
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1260 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski