Amino acid dipepetide frequency for Halomonas phage phiHAP-1 (isolate -/Gulf of Mexico/-/2001) (Bacteriophage phiHAP-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.072AlaAla: 15.072 ± 2.481
0.784AlaCys: 0.784 ± 0.251
6.621AlaAsp: 6.621 ± 0.882
7.405AlaGlu: 7.405 ± 0.914
3.746AlaPhe: 3.746 ± 0.435
7.231AlaGly: 7.231 ± 1.449
2.091AlaHis: 2.091 ± 0.429
4.879AlaIle: 4.879 ± 0.637
4.356AlaLys: 4.356 ± 0.689
10.193AlaLeu: 10.193 ± 0.881
2.701AlaMet: 2.701 ± 0.407
2.875AlaAsn: 2.875 ± 0.611
4.182AlaPro: 4.182 ± 0.587
3.398AlaGln: 3.398 ± 0.589
9.061AlaArg: 9.061 ± 0.758
6.099AlaSer: 6.099 ± 0.746
5.75AlaThr: 5.75 ± 0.726
7.144AlaVal: 7.144 ± 0.645
2.527AlaTrp: 2.527 ± 0.42
2.265AlaTyr: 2.265 ± 0.46
0.0AlaXaa: 0.0 ± 0.0
Cys
0.523CysAla: 0.523 ± 0.207
0.261CysCys: 0.261 ± 0.138
0.61CysAsp: 0.61 ± 0.239
1.045CysGlu: 1.045 ± 0.322
0.174CysPhe: 0.174 ± 0.113
0.436CysGly: 0.436 ± 0.152
0.436CysHis: 0.436 ± 0.17
0.348CysIle: 0.348 ± 0.167
0.261CysLys: 0.261 ± 0.158
0.523CysLeu: 0.523 ± 0.207
0.0CysMet: 0.0 ± 0.0
0.261CysAsn: 0.261 ± 0.195
0.523CysPro: 0.523 ± 0.209
0.61CysGln: 0.61 ± 0.256
0.958CysArg: 0.958 ± 0.331
0.61CysSer: 0.61 ± 0.247
0.697CysThr: 0.697 ± 0.266
0.523CysVal: 0.523 ± 0.181
0.261CysTrp: 0.261 ± 0.136
0.174CysTyr: 0.174 ± 0.154
0.0CysXaa: 0.0 ± 0.0
Asp
7.144AspAla: 7.144 ± 0.697
0.697AspCys: 0.697 ± 0.212
4.792AspAsp: 4.792 ± 0.746
5.663AspGlu: 5.663 ± 0.625
1.481AspPhe: 1.481 ± 0.296
5.837AspGly: 5.837 ± 0.687
2.091AspHis: 2.091 ± 0.527
3.136AspIle: 3.136 ± 0.492
2.004AspLys: 2.004 ± 0.394
4.879AspLeu: 4.879 ± 0.645
1.742AspMet: 1.742 ± 0.333
1.22AspAsn: 1.22 ± 0.328
2.788AspPro: 2.788 ± 0.674
2.701AspGln: 2.701 ± 0.44
4.095AspArg: 4.095 ± 0.64
2.962AspSer: 2.962 ± 0.418
3.398AspThr: 3.398 ± 0.468
3.311AspVal: 3.311 ± 0.477
1.133AspTrp: 1.133 ± 0.332
1.742AspTyr: 1.742 ± 0.32
0.0AspXaa: 0.0 ± 0.0
Glu
7.754GluAla: 7.754 ± 0.899
0.871GluCys: 0.871 ± 0.276
3.136GluAsp: 3.136 ± 0.595
5.315GluGlu: 5.315 ± 0.774
2.265GluPhe: 2.265 ± 0.463
4.792GluGly: 4.792 ± 0.856
1.655GluHis: 1.655 ± 0.312
4.095GluIle: 4.095 ± 0.613
2.701GluLys: 2.701 ± 0.567
7.754GluLeu: 7.754 ± 0.878
2.265GluMet: 2.265 ± 0.36
1.568GluAsn: 1.568 ± 0.294
2.701GluPro: 2.701 ± 0.449
4.53GluGln: 4.53 ± 0.839
6.97GluArg: 6.97 ± 0.781
3.572GluSer: 3.572 ± 0.588
3.746GluThr: 3.746 ± 0.472
6.012GluVal: 6.012 ± 0.665
1.481GluTrp: 1.481 ± 0.39
2.701GluTyr: 2.701 ± 0.313
0.0GluXaa: 0.0 ± 0.0
Phe
3.136PheAla: 3.136 ± 0.457
0.174PheCys: 0.174 ± 0.117
2.091PheAsp: 2.091 ± 0.336
2.004PheGlu: 2.004 ± 0.289
0.784PhePhe: 0.784 ± 0.262
2.614PheGly: 2.614 ± 0.44
0.61PheHis: 0.61 ± 0.249
1.22PheIle: 1.22 ± 0.284
1.742PheLys: 1.742 ± 0.404
1.045PheLeu: 1.045 ± 0.249
1.22PheMet: 1.22 ± 0.341
0.958PheAsn: 0.958 ± 0.251
1.307PhePro: 1.307 ± 0.304
0.348PheGln: 0.348 ± 0.177
1.83PheArg: 1.83 ± 0.375
2.352PheSer: 2.352 ± 0.525
1.568PheThr: 1.568 ± 0.347
2.701PheVal: 2.701 ± 0.449
0.174PheTrp: 0.174 ± 0.125
1.394PheTyr: 1.394 ± 0.337
0.0PheXaa: 0.0 ± 0.0
Gly
6.273GlyAla: 6.273 ± 1.206
1.045GlyCys: 1.045 ± 0.434
4.966GlyAsp: 4.966 ± 0.633
6.099GlyGlu: 6.099 ± 0.967
2.788GlyPhe: 2.788 ± 0.437
6.36GlyGly: 6.36 ± 1.118
0.697GlyHis: 0.697 ± 0.235
3.224GlyIle: 3.224 ± 0.437
3.224GlyLys: 3.224 ± 0.611
5.576GlyLeu: 5.576 ± 0.565
2.352GlyMet: 2.352 ± 0.476
2.875GlyAsn: 2.875 ± 0.487
2.004GlyPro: 2.004 ± 0.434
3.572GlyGln: 3.572 ± 0.445
5.315GlyArg: 5.315 ± 0.594
4.008GlySer: 4.008 ± 0.701
4.008GlyThr: 4.008 ± 0.613
5.924GlyVal: 5.924 ± 0.625
1.568GlyTrp: 1.568 ± 0.334
3.224GlyTyr: 3.224 ± 0.455
0.0GlyXaa: 0.0 ± 0.0
His
2.439HisAla: 2.439 ± 0.365
0.348HisCys: 0.348 ± 0.162
1.394HisAsp: 1.394 ± 0.347
1.22HisGlu: 1.22 ± 0.397
0.697HisPhe: 0.697 ± 0.246
1.568HisGly: 1.568 ± 0.466
0.523HisHis: 0.523 ± 0.218
1.307HisIle: 1.307 ± 0.453
0.871HisLys: 0.871 ± 0.334
2.004HisLeu: 2.004 ± 0.358
0.174HisMet: 0.174 ± 0.131
0.697HisAsn: 0.697 ± 0.226
1.133HisPro: 1.133 ± 0.3
1.394HisGln: 1.394 ± 0.334
2.265HisArg: 2.265 ± 0.573
0.958HisSer: 0.958 ± 0.237
1.045HisThr: 1.045 ± 0.332
1.307HisVal: 1.307 ± 0.394
0.61HisTrp: 0.61 ± 0.228
0.523HisTyr: 0.523 ± 0.183
0.0HisXaa: 0.0 ± 0.0
Ile
5.053IleAla: 5.053 ± 0.725
0.348IleCys: 0.348 ± 0.215
4.618IleAsp: 4.618 ± 0.729
5.663IleGlu: 5.663 ± 0.825
0.784IlePhe: 0.784 ± 0.191
3.224IleGly: 3.224 ± 0.579
0.958IleHis: 0.958 ± 0.338
1.22IleIle: 1.22 ± 0.399
1.394IleLys: 1.394 ± 0.358
2.788IleLeu: 2.788 ± 0.405
1.045IleMet: 1.045 ± 0.276
1.83IleAsn: 1.83 ± 0.292
2.178IlePro: 2.178 ± 0.416
1.568IleGln: 1.568 ± 0.377
3.659IleArg: 3.659 ± 0.526
2.962IleSer: 2.962 ± 0.444
2.614IleThr: 2.614 ± 0.383
2.788IleVal: 2.788 ± 0.59
0.261IleTrp: 0.261 ± 0.138
1.133IleTyr: 1.133 ± 0.292
0.0IleXaa: 0.0 ± 0.0
Lys
4.443LysAla: 4.443 ± 0.776
0.436LysCys: 0.436 ± 0.199
1.742LysAsp: 1.742 ± 0.405
2.091LysGlu: 2.091 ± 0.416
0.436LysPhe: 0.436 ± 0.228
2.701LysGly: 2.701 ± 0.524
0.958LysHis: 0.958 ± 0.327
1.133LysIle: 1.133 ± 0.262
2.527LysLys: 2.527 ± 0.564
3.224LysLeu: 3.224 ± 0.503
0.61LysMet: 0.61 ± 0.3
1.394LysAsn: 1.394 ± 0.403
2.178LysPro: 2.178 ± 0.52
1.83LysGln: 1.83 ± 0.332
4.356LysArg: 4.356 ± 0.786
1.83LysSer: 1.83 ± 0.38
1.481LysThr: 1.481 ± 0.428
3.485LysVal: 3.485 ± 0.547
0.523LysTrp: 0.523 ± 0.2
0.61LysTyr: 0.61 ± 0.2
0.0LysXaa: 0.0 ± 0.0
Leu
9.584LeuAla: 9.584 ± 1.039
0.784LeuCys: 0.784 ± 0.331
6.186LeuAsp: 6.186 ± 0.529
6.012LeuGlu: 6.012 ± 0.474
2.004LeuPhe: 2.004 ± 0.414
5.663LeuGly: 5.663 ± 0.858
2.091LeuHis: 2.091 ± 0.377
5.402LeuIle: 5.402 ± 0.6
2.875LeuLys: 2.875 ± 0.53
6.796LeuLeu: 6.796 ± 0.699
1.742LeuMet: 1.742 ± 0.318
3.572LeuAsn: 3.572 ± 0.523
3.485LeuPro: 3.485 ± 0.516
4.182LeuGln: 4.182 ± 0.61
6.273LeuArg: 6.273 ± 0.687
5.227LeuSer: 5.227 ± 0.759
4.53LeuThr: 4.53 ± 0.57
5.402LeuVal: 5.402 ± 0.513
1.22LeuTrp: 1.22 ± 0.425
1.568LeuTyr: 1.568 ± 0.446
0.0LeuXaa: 0.0 ± 0.0
Met
3.049MetAla: 3.049 ± 0.433
0.261MetCys: 0.261 ± 0.133
1.481MetAsp: 1.481 ± 0.334
1.83MetGlu: 1.83 ± 0.295
0.523MetPhe: 0.523 ± 0.214
1.568MetGly: 1.568 ± 0.367
0.523MetHis: 0.523 ± 0.197
0.697MetIle: 0.697 ± 0.268
1.045MetLys: 1.045 ± 0.329
2.091MetLeu: 2.091 ± 0.595
0.436MetMet: 0.436 ± 0.18
0.697MetAsn: 0.697 ± 0.25
1.394MetPro: 1.394 ± 0.244
1.22MetGln: 1.22 ± 0.413
2.439MetArg: 2.439 ± 0.355
1.917MetSer: 1.917 ± 0.486
1.22MetThr: 1.22 ± 0.285
1.394MetVal: 1.394 ± 0.306
0.174MetTrp: 0.174 ± 0.107
0.523MetTyr: 0.523 ± 0.215
0.0MetXaa: 0.0 ± 0.0
Asn
3.572AsnAla: 3.572 ± 0.431
0.436AsnCys: 0.436 ± 0.169
2.701AsnAsp: 2.701 ± 0.587
2.004AsnGlu: 2.004 ± 0.444
0.784AsnPhe: 0.784 ± 0.288
3.224AsnGly: 3.224 ± 0.508
0.958AsnHis: 0.958 ± 0.302
0.61AsnIle: 0.61 ± 0.199
0.958AsnLys: 0.958 ± 0.302
2.439AsnLeu: 2.439 ± 0.469
0.261AsnMet: 0.261 ± 0.158
1.307AsnAsn: 1.307 ± 0.392
1.655AsnPro: 1.655 ± 0.325
1.481AsnGln: 1.481 ± 0.297
2.701AsnArg: 2.701 ± 0.442
2.004AsnSer: 2.004 ± 0.482
1.917AsnThr: 1.917 ± 0.316
2.352AsnVal: 2.352 ± 0.486
0.61AsnTrp: 0.61 ± 0.198
0.436AsnTyr: 0.436 ± 0.167
0.0AsnXaa: 0.0 ± 0.0
Pro
4.182ProAla: 4.182 ± 0.804
0.174ProCys: 0.174 ± 0.129
3.049ProAsp: 3.049 ± 0.599
2.352ProGlu: 2.352 ± 0.388
1.83ProPhe: 1.83 ± 0.412
3.311ProGly: 3.311 ± 0.512
1.22ProHis: 1.22 ± 0.342
1.742ProIle: 1.742 ± 0.411
1.655ProLys: 1.655 ± 0.412
3.311ProLeu: 3.311 ± 0.608
0.784ProMet: 0.784 ± 0.216
2.004ProAsn: 2.004 ± 0.406
2.352ProPro: 2.352 ± 0.567
1.83ProGln: 1.83 ± 0.409
2.439ProArg: 2.439 ± 0.615
3.049ProSer: 3.049 ± 0.533
2.614ProThr: 2.614 ± 0.47
3.572ProVal: 3.572 ± 0.589
0.61ProTrp: 0.61 ± 0.201
2.004ProTyr: 2.004 ± 0.437
0.0ProXaa: 0.0 ± 0.0
Gln
5.663GlnAla: 5.663 ± 0.841
0.348GlnCys: 0.348 ± 0.153
0.784GlnAsp: 0.784 ± 0.247
3.311GlnGlu: 3.311 ± 0.568
0.958GlnPhe: 0.958 ± 0.227
3.746GlnGly: 3.746 ± 0.576
0.784GlnHis: 0.784 ± 0.274
2.091GlnIle: 2.091 ± 0.403
0.958GlnLys: 0.958 ± 0.285
3.049GlnLeu: 3.049 ± 0.425
1.394GlnMet: 1.394 ± 0.339
1.481GlnAsn: 1.481 ± 0.32
2.091GlnPro: 2.091 ± 0.479
2.352GlnGln: 2.352 ± 0.473
4.618GlnArg: 4.618 ± 0.626
2.875GlnSer: 2.875 ± 0.464
2.091GlnThr: 2.091 ± 0.518
2.614GlnVal: 2.614 ± 0.414
0.61GlnTrp: 0.61 ± 0.245
1.133GlnTyr: 1.133 ± 0.259
0.0GlnXaa: 0.0 ± 0.0
Arg
6.273ArgAla: 6.273 ± 0.466
0.436ArgCys: 0.436 ± 0.222
3.398ArgAsp: 3.398 ± 0.481
7.057ArgGlu: 7.057 ± 0.894
2.875ArgPhe: 2.875 ± 0.359
5.053ArgGly: 5.053 ± 0.697
2.091ArgHis: 2.091 ± 0.601
4.705ArgIle: 4.705 ± 0.635
3.136ArgLys: 3.136 ± 0.547
8.887ArgLeu: 8.887 ± 1.05
2.439ArgMet: 2.439 ± 0.457
2.265ArgAsn: 2.265 ± 0.357
2.962ArgPro: 2.962 ± 0.423
3.833ArgGln: 3.833 ± 0.566
7.493ArgArg: 7.493 ± 0.874
3.572ArgSer: 3.572 ± 0.575
2.875ArgThr: 2.875 ± 0.378
5.75ArgVal: 5.75 ± 0.598
2.439ArgTrp: 2.439 ± 0.375
2.701ArgTyr: 2.701 ± 0.412
0.0ArgXaa: 0.0 ± 0.0
Ser
4.705SerAla: 4.705 ± 0.728
0.348SerCys: 0.348 ± 0.148
3.659SerAsp: 3.659 ± 0.503
4.095SerGlu: 4.095 ± 0.632
2.178SerPhe: 2.178 ± 0.359
4.966SerGly: 4.966 ± 0.649
1.045SerHis: 1.045 ± 0.284
2.614SerIle: 2.614 ± 0.497
2.265SerLys: 2.265 ± 0.503
3.833SerLeu: 3.833 ± 0.574
1.394SerMet: 1.394 ± 0.267
1.83SerAsn: 1.83 ± 0.366
2.788SerPro: 2.788 ± 0.42
2.788SerGln: 2.788 ± 0.512
4.705SerArg: 4.705 ± 0.693
3.572SerSer: 3.572 ± 0.681
2.962SerThr: 2.962 ± 0.402
4.443SerVal: 4.443 ± 0.552
0.697SerTrp: 0.697 ± 0.225
1.568SerTyr: 1.568 ± 0.458
0.0SerXaa: 0.0 ± 0.0
Thr
5.663ThrAla: 5.663 ± 1.012
0.0ThrCys: 0.0 ± 0.0
3.311ThrAsp: 3.311 ± 0.411
4.356ThrGlu: 4.356 ± 0.453
2.091ThrPhe: 2.091 ± 0.425
5.315ThrGly: 5.315 ± 0.627
1.394ThrHis: 1.394 ± 0.38
2.439ThrIle: 2.439 ± 0.674
2.265ThrLys: 2.265 ± 0.438
6.36ThrLeu: 6.36 ± 0.855
0.523ThrMet: 0.523 ± 0.197
1.655ThrAsn: 1.655 ± 0.274
2.962ThrPro: 2.962 ± 0.606
1.742ThrGln: 1.742 ± 0.413
2.701ThrArg: 2.701 ± 0.445
1.655ThrSer: 1.655 ± 0.373
4.269ThrThr: 4.269 ± 0.579
3.659ThrVal: 3.659 ± 0.535
0.784ThrTrp: 0.784 ± 0.218
1.045ThrTyr: 1.045 ± 0.295
0.0ThrXaa: 0.0 ± 0.0
Val
8.277ValAla: 8.277 ± 1.076
0.523ValCys: 0.523 ± 0.185
5.315ValAsp: 5.315 ± 0.695
6.012ValGlu: 6.012 ± 0.744
2.265ValPhe: 2.265 ± 0.386
5.227ValGly: 5.227 ± 0.749
1.22ValHis: 1.22 ± 0.333
3.659ValIle: 3.659 ± 0.599
1.568ValLys: 1.568 ± 0.387
5.489ValLeu: 5.489 ± 0.733
2.178ValMet: 2.178 ± 0.384
2.962ValAsn: 2.962 ± 0.538
3.136ValPro: 3.136 ± 0.688
1.917ValGln: 1.917 ± 0.426
4.269ValArg: 4.269 ± 0.702
4.008ValSer: 4.008 ± 0.531
5.227ValThr: 5.227 ± 0.872
3.746ValVal: 3.746 ± 0.895
0.958ValTrp: 0.958 ± 0.271
1.22ValTyr: 1.22 ± 0.331
0.087ValXaa: 0.087 ± 0.076
Trp
2.091TrpAla: 2.091 ± 0.586
0.261TrpCys: 0.261 ± 0.246
0.784TrpAsp: 0.784 ± 0.219
0.871TrpGlu: 0.871 ± 0.24
0.436TrpPhe: 0.436 ± 0.167
0.871TrpGly: 0.871 ± 0.267
0.61TrpHis: 0.61 ± 0.256
0.61TrpIle: 0.61 ± 0.175
0.958TrpLys: 0.958 ± 0.267
2.614TrpLeu: 2.614 ± 0.413
0.436TrpMet: 0.436 ± 0.22
0.348TrpAsn: 0.348 ± 0.178
1.045TrpPro: 1.045 ± 0.37
0.871TrpGln: 0.871 ± 0.252
1.394TrpArg: 1.394 ± 0.312
1.133TrpSer: 1.133 ± 0.305
0.348TrpThr: 0.348 ± 0.18
1.307TrpVal: 1.307 ± 0.342
0.348TrpTrp: 0.348 ± 0.199
0.174TrpTyr: 0.174 ± 0.148
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.485TyrAla: 3.485 ± 0.508
0.697TyrCys: 0.697 ± 0.211
2.178TyrAsp: 2.178 ± 0.431
1.481TyrGlu: 1.481 ± 0.452
0.174TyrPhe: 0.174 ± 0.129
1.394TyrGly: 1.394 ± 0.43
0.523TyrHis: 0.523 ± 0.203
0.958TyrIle: 0.958 ± 0.297
1.307TyrLys: 1.307 ± 0.244
1.742TyrLeu: 1.742 ± 0.385
0.697TyrMet: 0.697 ± 0.184
0.61TyrAsn: 0.61 ± 0.245
1.22TyrPro: 1.22 ± 0.317
0.784TyrGln: 0.784 ± 0.215
2.701TyrArg: 2.701 ± 0.48
2.091TyrSer: 2.091 ± 0.389
1.742TyrThr: 1.742 ± 0.344
1.83TyrVal: 1.83 ± 0.386
0.523TyrTrp: 0.523 ± 0.217
0.348TyrTyr: 0.348 ± 0.168
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.087XaaThr: 0.087 ± 0.076
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 46 proteins (11479 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski