Amino acid dipepetide frequency for Agromyces sp. MMS17-SY077

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.649AlaAla: 24.649 ± 0.261	0.613AlaCys: 0.613 ± 0.022	9.581AlaAsp: 9.581 ± 0.092	9.509AlaGlu: 9.509 ± 0.107	4.313AlaPhe: 4.313 ± 0.063	14.104AlaGly: 14.104 ± 0.124	2.374AlaHis: 2.374 ± 0.045	6.242AlaIle: 6.242 ± 0.08	2.607AlaLys: 2.607 ± 0.067	14.758AlaLeu: 14.758 ± 0.163	2.543AlaMet: 2.543 ± 0.048	2.421AlaAsn: 2.421 ± 0.052	7.424AlaPro: 7.424 ± 0.099	3.228AlaGln: 3.228 ± 0.054	9.688AlaArg: 9.688 ± 0.125	7.476AlaSer: 7.476 ± 0.092	7.377AlaThr: 7.377 ± 0.098	12.738AlaVal: 12.738 ± 0.12	2.067AlaTrp: 2.067 ± 0.044	2.492AlaTyr: 2.492 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.59CysAla: 0.59 ± 0.027	0.048CysCys: 0.048 ± 0.006	0.238CysAsp: 0.238 ± 0.016	0.208CysGlu: 0.208 ± 0.014	0.19CysPhe: 0.19 ± 0.014	0.485CysGly: 0.485 ± 0.023	0.09CysHis: 0.09 ± 0.009	0.174CysIle: 0.174 ± 0.012	0.052CysLys: 0.052 ± 0.006	0.414CysLeu: 0.414 ± 0.018	0.066CysMet: 0.066 ± 0.007	0.094CysAsn: 0.094 ± 0.009	0.265CysPro: 0.265 ± 0.016	0.09CysGln: 0.09 ± 0.009	0.299CysArg: 0.299 ± 0.016	0.317CysSer: 0.317 ± 0.019	0.306CysThr: 0.306 ± 0.024	0.361CysVal: 0.361 ± 0.018	0.07CysTrp: 0.07 ± 0.009	0.088CysTyr: 0.088 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	10.156AspAla: 10.156 ± 0.117	0.239AspCys: 0.239 ± 0.016	4.452AspAsp: 4.452 ± 0.084	4.707AspGlu: 4.707 ± 0.071	1.803AspPhe: 1.803 ± 0.046	6.769AspGly: 6.769 ± 0.093	1.037AspHis: 1.037 ± 0.031	1.719AspIle: 1.719 ± 0.042	0.735AspLys: 0.735 ± 0.028	6.499AspLeu: 6.499 ± 0.087	0.614AspMet: 0.614 ± 0.023	0.761AspAsn: 0.761 ± 0.027	4.568AspPro: 4.568 ± 0.068	1.306AspGln: 1.306 ± 0.034	4.965AspArg: 4.965 ± 0.077	2.43AspSer: 2.43 ± 0.046	2.461AspThr: 2.461 ± 0.048	5.501AspVal: 5.501 ± 0.071	1.058AspTrp: 1.058 ± 0.031	1.32AspTyr: 1.32 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	7.916GluAla: 7.916 ± 0.097	0.222GluCys: 0.222 ± 0.015	2.731GluAsp: 2.731 ± 0.055	2.799GluGlu: 2.799 ± 0.058	1.944GluPhe: 1.944 ± 0.037	4.019GluGly: 4.019 ± 0.073	1.689GluHis: 1.689 ± 0.041	2.582GluIle: 2.582 ± 0.055	0.853GluLys: 0.853 ± 0.032	7.363GluLeu: 7.363 ± 0.094	0.742GluMet: 0.742 ± 0.026	0.952GluAsn: 0.952 ± 0.032	3.677GluPro: 3.677 ± 0.066	2.13GluGln: 2.13 ± 0.047	6.054GluArg: 6.054 ± 0.096	3.041GluSer: 3.041 ± 0.057	3.175GluThr: 3.175 ± 0.052	4.612GluVal: 4.612 ± 0.071	0.965GluTrp: 0.965 ± 0.032	1.193GluTyr: 1.193 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	4.913PheAla: 4.913 ± 0.068	0.147PheCys: 0.147 ± 0.011	2.489PheAsp: 2.489 ± 0.047	1.963PheGlu: 1.963 ± 0.045	1.01PhePhe: 1.01 ± 0.038	3.718PheGly: 3.718 ± 0.053	0.565PheHis: 0.565 ± 0.024	1.12PheIle: 1.12 ± 0.037	0.419PheLys: 0.419 ± 0.02	2.919PheLeu: 2.919 ± 0.052	0.388PheMet: 0.388 ± 0.019	0.607PheAsn: 0.607 ± 0.024	1.41PhePro: 1.41 ± 0.036	0.728PheGln: 0.728 ± 0.024	1.89PheArg: 1.89 ± 0.044	1.531PheSer: 1.531 ± 0.038	1.988PheThr: 1.988 ± 0.047	2.963PheVal: 2.963 ± 0.054	0.518PheTrp: 0.518 ± 0.025	0.587PheTyr: 0.587 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	12.391GlyAla: 12.391 ± 0.11	0.518GlyCys: 0.518 ± 0.02	5.419GlyAsp: 5.419 ± 0.088	5.282GlyGlu: 5.282 ± 0.075	3.577GlyPhe: 3.577 ± 0.054	8.48GlyGly: 8.48 ± 0.098	1.677GlyHis: 1.677 ± 0.041	4.986GlyIle: 4.986 ± 0.071	1.983GlyLys: 1.983 ± 0.055	9.77GlyLeu: 9.77 ± 0.11	1.874GlyMet: 1.874 ± 0.04	1.628GlyAsn: 1.628 ± 0.042	4.153GlyPro: 4.153 ± 0.065	2.177GlyGln: 2.177 ± 0.04	7.039GlyArg: 7.039 ± 0.092	5.36GlySer: 5.36 ± 0.075	5.83GlyThr: 5.83 ± 0.082	8.33GlyVal: 8.33 ± 0.093	1.743GlyTrp: 1.743 ± 0.042	2.278GlyTyr: 2.278 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.208HisAla: 2.208 ± 0.048	0.097HisCys: 0.097 ± 0.01	1.315HisAsp: 1.315 ± 0.036	1.151HisGlu: 1.151 ± 0.03	0.548HisPhe: 0.548 ± 0.02	2.023HisGly: 2.023 ± 0.046	0.454HisHis: 0.454 ± 0.021	0.517HisIle: 0.517 ± 0.025	0.208HisLys: 0.208 ± 0.015	1.911HisLeu: 1.911 ± 0.045	0.212HisMet: 0.212 ± 0.014	0.288HisAsn: 0.288 ± 0.019	1.511HisPro: 1.511 ± 0.035	0.394HisGln: 0.394 ± 0.018	1.613HisArg: 1.613 ± 0.036	0.843HisSer: 0.843 ± 0.028	0.789HisThr: 0.789 ± 0.03	1.591HisVal: 1.591 ± 0.036	0.289HisTrp: 0.289 ± 0.016	0.412HisTyr: 0.412 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.184IleAla: 7.184 ± 0.086	0.196IleCys: 0.196 ± 0.014	3.165IleAsp: 3.165 ± 0.054	2.717IleGlu: 2.717 ± 0.055	0.996IlePhe: 0.996 ± 0.03	4.67IleGly: 4.67 ± 0.077	0.605IleHis: 0.605 ± 0.025	1.47IleIle: 1.47 ± 0.047	0.669IleLys: 0.669 ± 0.03	3.621IleLeu: 3.621 ± 0.059	0.496IleMet: 0.496 ± 0.023	0.671IleAsn: 0.671 ± 0.024	2.279IlePro: 2.279 ± 0.043	0.84IleGln: 0.84 ± 0.029	2.643IleArg: 2.643 ± 0.05	1.987IleSer: 1.987 ± 0.05	2.247IleThr: 2.247 ± 0.054	4.515IleVal: 4.515 ± 0.067	0.525IleTrp: 0.525 ± 0.021	0.628IleTyr: 0.628 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.119LysAla: 2.119 ± 0.056	0.058LysCys: 0.058 ± 0.007	0.807LysAsp: 0.807 ± 0.033	0.734LysGlu: 0.734 ± 0.032	0.512LysPhe: 0.512 ± 0.019	1.251LysGly: 1.251 ± 0.039	0.414LysHis: 0.414 ± 0.022	0.762LysIle: 0.762 ± 0.029	0.5LysLys: 0.5 ± 0.029	1.878LysLeu: 1.878 ± 0.049	0.256LysMet: 0.256 ± 0.015	0.378LysAsn: 0.378 ± 0.019	1.09LysPro: 1.09 ± 0.034	0.614LysGln: 0.614 ± 0.025	1.4LysArg: 1.4 ± 0.043	1.056LysSer: 1.056 ± 0.03	1.107LysThr: 1.107 ± 0.032	1.402LysVal: 1.402 ± 0.037	0.244LysTrp: 0.244 ± 0.016	0.41LysTyr: 0.41 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	16.715LeuAla: 16.715 ± 0.187	0.422LeuCys: 0.422 ± 0.018	7.39LeuAsp: 7.39 ± 0.086	5.892LeuGlu: 5.892 ± 0.078	2.861LeuPhe: 2.861 ± 0.05	10.125LeuGly: 10.125 ± 0.106	1.815LeuHis: 1.815 ± 0.033	3.845LeuIle: 3.845 ± 0.062	1.478LeuLys: 1.478 ± 0.043	10.387LeuLeu: 10.387 ± 0.158	1.315LeuMet: 1.315 ± 0.038	1.545LeuAsn: 1.545 ± 0.035	5.735LeuPro: 5.735 ± 0.082	2.341LeuGln: 2.341 ± 0.045	7.184LeuArg: 7.184 ± 0.111	4.916LeuSer: 4.916 ± 0.062	5.445LeuThr: 5.445 ± 0.074	10.855LeuVal: 10.855 ± 0.132	1.192LeuTrp: 1.192 ± 0.036	1.562LeuTyr: 1.562 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	1.728MetAla: 1.728 ± 0.041	0.074MetCys: 0.074 ± 0.008	0.681MetAsp: 0.681 ± 0.026	0.522MetGlu: 0.522 ± 0.022	0.411MetPhe: 0.411 ± 0.02	1.151MetGly: 1.151 ± 0.036	0.3MetHis: 0.3 ± 0.017	0.649MetIle: 0.649 ± 0.029	0.276MetLys: 0.276 ± 0.014	1.833MetLeu: 1.833 ± 0.039	0.192MetMet: 0.192 ± 0.015	0.398MetAsn: 0.398 ± 0.019	1.106MetPro: 1.106 ± 0.031	0.492MetGln: 0.492 ± 0.019	1.19MetArg: 1.19 ± 0.032	1.228MetSer: 1.228 ± 0.031	1.44MetThr: 1.44 ± 0.033	1.04MetVal: 1.04 ± 0.03	0.173MetTrp: 0.173 ± 0.013	0.24MetTyr: 0.24 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.336AsnAla: 2.336 ± 0.047	0.104AsnCys: 0.104 ± 0.009	0.978AsnAsp: 0.978 ± 0.029	0.866AsnGlu: 0.866 ± 0.027	0.592AsnPhe: 0.592 ± 0.022	1.824AsnGly: 1.824 ± 0.043	0.32AsnHis: 0.32 ± 0.018	0.618AsnIle: 0.618 ± 0.025	0.294AsnLys: 0.294 ± 0.019	1.784AsnLeu: 1.784 ± 0.04	0.246AsnMet: 0.246 ± 0.016	0.387AsnAsn: 0.387 ± 0.02	1.479AsnPro: 1.479 ± 0.039	0.477AsnGln: 0.477 ± 0.024	1.28AsnArg: 1.28 ± 0.036	0.891AsnSer: 0.891 ± 0.034	1.015AsnThr: 1.015 ± 0.032	1.535AsnVal: 1.535 ± 0.043	0.292AsnTrp: 0.292 ± 0.015	0.414AsnTyr: 0.414 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	8.514ProAla: 8.514 ± 0.105	0.169ProCys: 0.169 ± 0.012	4.047ProAsp: 4.047 ± 0.069	4.242ProGlu: 4.242 ± 0.057	1.778ProPhe: 1.778 ± 0.041	5.631ProGly: 5.631 ± 0.079	0.993ProHis: 0.993 ± 0.028	2.324ProIle: 2.324 ± 0.047	1.114ProLys: 1.114 ± 0.033	4.832ProLeu: 4.832 ± 0.069	0.767ProMet: 0.767 ± 0.025	1.128ProAsn: 1.128 ± 0.034	2.453ProPro: 2.453 ± 0.057	1.272ProGln: 1.272 ± 0.037	3.356ProArg: 3.356 ± 0.059	2.935ProSer: 2.935 ± 0.06	3.506ProThr: 3.506 ± 0.065	5.242ProVal: 5.242 ± 0.083	0.935ProTrp: 0.935 ± 0.034	1.034ProTyr: 1.034 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.194GlnAla: 3.194 ± 0.056	0.114GlnCys: 0.114 ± 0.01	1.113GlnAsp: 1.113 ± 0.035	1.116GlnGlu: 1.116 ± 0.036	0.796GlnPhe: 0.796 ± 0.025	1.888GlnGly: 1.888 ± 0.045	0.555GlnHis: 0.555 ± 0.023	1.115GlnIle: 1.115 ± 0.033	0.45GlnLys: 0.45 ± 0.024	2.795GlnLeu: 2.795 ± 0.051	0.327GlnMet: 0.327 ± 0.016	0.495GlnAsn: 0.495 ± 0.025	1.445GlnPro: 1.445 ± 0.038	1.007GlnGln: 1.007 ± 0.038	2.075GlnArg: 2.075 ± 0.045	1.339GlnSer: 1.339 ± 0.036	1.372GlnThr: 1.372 ± 0.035	2.06GlnVal: 2.06 ± 0.044	0.431GlnTrp: 0.431 ± 0.019	0.613GlnTyr: 0.613 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	9.54ArgAla: 9.54 ± 0.122	0.289ArgCys: 0.289 ± 0.015	4.133ArgAsp: 4.133 ± 0.071	4.266ArgGlu: 4.266 ± 0.071	2.638ArgPhe: 2.638 ± 0.045	5.703ArgGly: 5.703 ± 0.081	1.48ArgHis: 1.48 ± 0.038	3.766ArgIle: 3.766 ± 0.058	1.269ArgLys: 1.269 ± 0.038	7.897ArgLeu: 7.897 ± 0.11	1.573ArgMet: 1.573 ± 0.038	1.283ArgAsn: 1.283 ± 0.039	4.059ArgPro: 4.059 ± 0.074	1.657ArgGln: 1.657 ± 0.038	7.065ArgArg: 7.065 ± 0.121	4.033ArgSer: 4.033 ± 0.064	4.373ArgThr: 4.373 ± 0.067	5.901ArgVal: 5.901 ± 0.077	1.247ArgTrp: 1.247 ± 0.034	1.518ArgTyr: 1.518 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.024SerAla: 7.024 ± 0.09	0.239SerCys: 0.239 ± 0.015	2.869SerAsp: 2.869 ± 0.057	2.655SerGlu: 2.655 ± 0.049	1.727SerPhe: 1.727 ± 0.046	5.733SerGly: 5.733 ± 0.062	0.805SerHis: 0.805 ± 0.027	2.584SerIle: 2.584 ± 0.05	1.031SerLys: 1.031 ± 0.035	5.162SerLeu: 5.162 ± 0.063	0.953SerMet: 0.953 ± 0.03	1.02SerAsn: 1.02 ± 0.033	2.976SerPro: 2.976 ± 0.055	1.133SerGln: 1.133 ± 0.033	3.454SerArg: 3.454 ± 0.061	2.975SerSer: 2.975 ± 0.06	3.46SerThr: 3.46 ± 0.07	4.387SerVal: 4.387 ± 0.072	0.853SerTrp: 0.853 ± 0.029	1.056SerTyr: 1.056 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	8.074ThrAla: 8.074 ± 0.09	0.246ThrCys: 0.246 ± 0.018	3.299ThrAsp: 3.299 ± 0.065	2.865ThrGlu: 2.865 ± 0.049	1.763ThrPhe: 1.763 ± 0.043	6.097ThrGly: 6.097 ± 0.093	0.942ThrHis: 0.942 ± 0.033	2.671ThrIle: 2.671 ± 0.054	1.11ThrLys: 1.11 ± 0.033	5.294ThrLeu: 5.294 ± 0.066	0.848ThrMet: 0.848 ± 0.025	1.108ThrAsn: 1.108 ± 0.034	3.738ThrPro: 3.738 ± 0.064	1.169ThrGln: 1.169 ± 0.03	3.277ThrArg: 3.277 ± 0.054	3.079ThrSer: 3.079 ± 0.055	3.503ThrThr: 3.503 ± 0.067	5.245ThrVal: 5.245 ± 0.088	0.899ThrTrp: 0.899 ± 0.029	1.021ThrTyr: 1.021 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	12.706ValAla: 12.706 ± 0.131	0.448ValCys: 0.448 ± 0.02	6.245ValAsp: 6.245 ± 0.08	5.378ValGlu: 5.378 ± 0.083	3.093ValPhe: 3.093 ± 0.056	7.744ValGly: 7.744 ± 0.099	1.637ValHis: 1.637 ± 0.037	3.747ValIle: 3.747 ± 0.062	1.381ValLys: 1.381 ± 0.038	9.973ValLeu: 9.973 ± 0.115	1.172ValMet: 1.172 ± 0.033	1.69ValAsn: 1.69 ± 0.046	5.217ValPro: 5.217 ± 0.062	2.242ValGln: 2.242 ± 0.046	6.281ValArg: 6.281 ± 0.077	4.615ValSer: 4.615 ± 0.072	4.706ValThr: 4.706 ± 0.081	9.539ValVal: 9.539 ± 0.114	1.178ValTrp: 1.178 ± 0.036	1.586ValTyr: 1.586 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.808TrpAla: 1.808 ± 0.043	0.094TrpCys: 0.094 ± 0.008	0.821TrpAsp: 0.821 ± 0.031	0.676TrpGlu: 0.676 ± 0.025	0.641TrpPhe: 0.641 ± 0.022	1.141TrpGly: 1.141 ± 0.038	0.321TrpHis: 0.321 ± 0.019	0.748TrpIle: 0.748 ± 0.025	0.307TrpLys: 0.307 ± 0.016	1.772TrpLeu: 1.772 ± 0.042	0.357TrpMet: 0.357 ± 0.017	0.48TrpAsn: 0.48 ± 0.021	0.699TrpPro: 0.699 ± 0.029	0.479TrpGln: 0.479 ± 0.02	1.201TrpArg: 1.201 ± 0.039	0.98TrpSer: 0.98 ± 0.032	0.98TrpThr: 0.98 ± 0.029	1.183TrpVal: 1.183 ± 0.034	0.408TrpTrp: 0.408 ± 0.02	0.337TrpTyr: 0.337 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.439TyrAla: 2.439 ± 0.054	0.107TyrCys: 0.107 ± 0.009	1.328TyrAsp: 1.328 ± 0.034	1.109TyrGlu: 1.109 ± 0.033	0.68TyrPhe: 0.68 ± 0.024	1.94TyrGly: 1.94 ± 0.039	0.3TyrHis: 0.3 ± 0.019	0.487TyrIle: 0.487 ± 0.023	0.255TyrLys: 0.255 ± 0.017	2.157TyrLeu: 2.157 ± 0.045	0.18TyrMet: 0.18 ± 0.013	0.397TyrAsn: 0.397 ± 0.021	0.99TyrPro: 0.99 ± 0.031	0.527TyrGln: 0.527 ± 0.023	1.741TyrArg: 1.741 ± 0.042	1.061TyrSer: 1.061 ± 0.03	1.171TyrThr: 1.171 ± 0.044	1.58TyrVal: 1.58 ± 0.039	0.343TyrTrp: 0.343 ± 0.018	0.452TyrTyr: 0.452 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3503 proteins (1161124 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---