Amino acid dipepetide frequency for Sanxia water strider virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.58AlaAla: 2.58 ± 0.536
1.147AlaCys: 1.147 ± 0.629
0.86AlaAsp: 0.86 ± 0.317
1.72AlaGlu: 1.72 ± 0.944
1.147AlaPhe: 1.147 ± 0.687
2.007AlaGly: 2.007 ± 0.452
0.86AlaHis: 0.86 ± 0.317
4.874AlaIle: 4.874 ± 0.971
0.573AlaLys: 0.573 ± 0.343
3.727AlaLeu: 3.727 ± 1.722
1.433AlaMet: 1.433 ± 0.645
2.294AlaAsn: 2.294 ± 0.541
0.573AlaPro: 0.573 ± 0.87
1.147AlaGln: 1.147 ± 0.911
2.294AlaArg: 2.294 ± 1.373
0.573AlaSer: 0.573 ± 0.315
3.727AlaThr: 3.727 ± 1.304
3.44AlaVal: 3.44 ± 1.718
1.147AlaTrp: 1.147 ± 0.418
1.72AlaTyr: 1.72 ± 0.64
0.0AlaXaa: 0.0 ± 0.0
Cys
0.287CysAla: 0.287 ± 0.157
0.0CysCys: 0.0 ± 0.0
0.86CysAsp: 0.86 ± 0.472
1.433CysGlu: 1.433 ± 0.323
0.86CysPhe: 0.86 ± 0.472
0.0CysGly: 0.0 ± 0.0
0.573CysHis: 0.573 ± 0.298
1.433CysIle: 1.433 ± 0.644
1.147CysLys: 1.147 ± 0.369
2.58CysLeu: 2.58 ± 0.904
0.573CysMet: 0.573 ± 0.315
1.433CysAsn: 1.433 ± 1.244
0.287CysPro: 0.287 ± 0.157
0.0CysGln: 0.0 ± 0.0
0.86CysArg: 0.86 ± 0.32
2.007CysSer: 2.007 ± 0.447
1.433CysThr: 1.433 ± 0.786
1.147CysVal: 1.147 ± 0.403
0.287CysTrp: 0.287 ± 0.157
0.287CysTyr: 0.287 ± 0.355
0.0CysXaa: 0.0 ± 0.0
Asp
1.433AspAla: 1.433 ± 0.382
2.294AspCys: 2.294 ± 0.468
4.3AspAsp: 4.3 ± 1.052
2.867AspGlu: 2.867 ± 1.053
2.294AspPhe: 2.294 ± 0.659
1.433AspGly: 1.433 ± 0.727
0.86AspHis: 0.86 ± 0.361
3.44AspIle: 3.44 ± 1.425
3.154AspLys: 3.154 ± 1.136
6.881AspLeu: 6.881 ± 1.149
2.007AspMet: 2.007 ± 0.912
2.58AspAsn: 2.58 ± 1.477
3.154AspPro: 3.154 ± 0.587
3.154AspGln: 3.154 ± 0.921
2.007AspArg: 2.007 ± 1.517
4.014AspSer: 4.014 ± 1.174
4.3AspThr: 4.3 ± 0.694
3.44AspVal: 3.44 ± 1.234
0.287AspTrp: 0.287 ± 0.355
4.3AspTyr: 4.3 ± 1.283
0.0AspXaa: 0.0 ± 0.0
Glu
2.867GluAla: 2.867 ± 0.663
0.573GluCys: 0.573 ± 0.315
3.154GluAsp: 3.154 ± 1.025
5.161GluGlu: 5.161 ± 1.463
1.147GluPhe: 1.147 ± 0.895
2.58GluGly: 2.58 ± 0.677
2.007GluHis: 2.007 ± 0.765
5.447GluIle: 5.447 ± 1.562
3.727GluLys: 3.727 ± 0.841
7.454GluLeu: 7.454 ± 0.527
2.294GluMet: 2.294 ± 0.943
3.727GluAsn: 3.727 ± 0.525
1.433GluPro: 1.433 ± 0.427
2.294GluGln: 2.294 ± 0.098
0.86GluArg: 0.86 ± 0.361
4.3GluSer: 4.3 ± 0.375
3.727GluThr: 3.727 ± 0.666
4.874GluVal: 4.874 ± 0.997
0.86GluTrp: 0.86 ± 0.472
1.72GluTyr: 1.72 ± 0.64
0.0GluXaa: 0.0 ± 0.0
Phe
0.86PheAla: 0.86 ± 0.759
0.287PheCys: 0.287 ± 0.157
3.727PheAsp: 3.727 ± 1.304
3.727PheGlu: 3.727 ± 0.547
2.007PhePhe: 2.007 ± 0.802
0.86PheGly: 0.86 ± 0.32
1.433PheHis: 1.433 ± 0.727
3.44PheIle: 3.44 ± 0.391
3.727PheLys: 3.727 ± 0.959
6.021PheLeu: 6.021 ± 0.907
0.86PheMet: 0.86 ± 0.317
2.294PheAsn: 2.294 ± 1.07
1.433PhePro: 1.433 ± 0.523
1.433PheGln: 1.433 ± 0.382
1.433PheArg: 1.433 ± 0.785
4.587PheSer: 4.587 ± 1.463
2.007PheThr: 2.007 ± 1.343
2.007PheVal: 2.007 ± 0.436
0.573PheTrp: 0.573 ± 0.315
1.147PheTyr: 1.147 ± 0.418
0.0PheXaa: 0.0 ± 0.0
Gly
1.147GlyAla: 1.147 ± 0.403
0.573GlyCys: 0.573 ± 0.315
3.44GlyAsp: 3.44 ± 1.359
1.433GlyGlu: 1.433 ± 0.519
2.867GlyPhe: 2.867 ± 0.47
2.007GlyGly: 2.007 ± 0.436
1.433GlyHis: 1.433 ± 0.523
3.154GlyIle: 3.154 ± 1.236
2.867GlyLys: 2.867 ± 1.27
3.727GlyLeu: 3.727 ± 0.53
1.72GlyMet: 1.72 ± 0.721
2.294GlyAsn: 2.294 ± 0.958
0.287GlyPro: 0.287 ± 0.435
0.573GlyGln: 0.573 ± 0.315
1.72GlyArg: 1.72 ± 0.594
5.734GlySer: 5.734 ± 0.403
3.44GlyThr: 3.44 ± 1.423
3.154GlyVal: 3.154 ± 0.987
0.287GlyTrp: 0.287 ± 0.157
1.433GlyTyr: 1.433 ± 0.523
0.0GlyXaa: 0.0 ± 0.0
His
0.287HisAla: 0.287 ± 0.355
0.0HisCys: 0.0 ± 0.0
1.147HisAsp: 1.147 ± 0.437
2.007HisGlu: 2.007 ± 0.802
2.007HisPhe: 2.007 ± 0.802
0.287HisGly: 0.287 ± 0.355
0.573HisHis: 0.573 ± 0.655
1.433HisIle: 1.433 ± 0.928
2.294HisLys: 2.294 ± 0.57
1.147HisLeu: 1.147 ± 0.403
1.147HisMet: 1.147 ± 0.734
1.147HisAsn: 1.147 ± 0.364
2.007HisPro: 2.007 ± 0.802
1.147HisGln: 1.147 ± 0.418
2.867HisArg: 2.867 ± 0.47
1.72HisSer: 1.72 ± 0.634
1.147HisThr: 1.147 ± 0.662
1.433HisVal: 1.433 ± 0.811
0.0HisTrp: 0.0 ± 0.0
1.433HisTyr: 1.433 ± 0.645
0.0HisXaa: 0.0 ± 0.0
Ile
4.587IleAla: 4.587 ± 0.594
0.573IleCys: 0.573 ± 0.343
5.447IleAsp: 5.447 ± 0.841
4.874IleGlu: 4.874 ± 0.977
3.727IlePhe: 3.727 ± 1.459
4.587IleGly: 4.587 ± 0.752
1.433IleHis: 1.433 ± 0.469
6.881IleIle: 6.881 ± 2.269
9.461IleLys: 9.461 ± 1.176
8.314IleLeu: 8.314 ± 1.899
1.72IleMet: 1.72 ± 0.48
3.727IleAsn: 3.727 ± 0.756
4.874IlePro: 4.874 ± 1.08
2.867IleGln: 2.867 ± 1.113
4.587IleArg: 4.587 ± 1.314
7.454IleSer: 7.454 ± 1.103
6.594IleThr: 6.594 ± 1.988
4.3IleVal: 4.3 ± 0.596
0.573IleTrp: 0.573 ± 0.367
2.294IleTyr: 2.294 ± 0.371
0.0IleXaa: 0.0 ± 0.0
Lys
2.58LysAla: 2.58 ± 0.442
0.86LysCys: 0.86 ± 0.317
2.294LysAsp: 2.294 ± 0.541
7.454LysGlu: 7.454 ± 1.39
3.44LysPhe: 3.44 ± 1.157
2.294LysGly: 2.294 ± 0.832
0.86LysHis: 0.86 ± 0.317
5.734LysIle: 5.734 ± 1.188
6.021LysLys: 6.021 ± 0.811
10.321LysLeu: 10.321 ± 1.925
1.433LysMet: 1.433 ± 0.502
5.734LysAsn: 5.734 ± 0.869
1.147LysPro: 1.147 ± 0.437
3.44LysGln: 3.44 ± 0.51
3.727LysArg: 3.727 ± 0.755
5.161LysSer: 5.161 ± 1.014
3.154LysThr: 3.154 ± 1.311
3.154LysVal: 3.154 ± 1.13
0.287LysTrp: 0.287 ± 0.157
3.154LysTyr: 3.154 ± 0.757
0.0LysXaa: 0.0 ± 0.0
Leu
4.587LeuAla: 4.587 ± 1.139
2.58LeuCys: 2.58 ± 0.83
7.454LeuAsp: 7.454 ± 1.501
4.874LeuGlu: 4.874 ± 0.911
5.447LeuPhe: 5.447 ± 1.328
6.307LeuGly: 6.307 ± 0.65
2.867LeuHis: 2.867 ± 0.712
10.894LeuIle: 10.894 ± 1.197
8.888LeuLys: 8.888 ± 1.354
12.615LeuLeu: 12.615 ± 1.638
2.294LeuMet: 2.294 ± 0.612
7.741LeuAsn: 7.741 ± 0.678
4.014LeuPro: 4.014 ± 0.807
2.007LeuGln: 2.007 ± 0.436
5.161LeuArg: 5.161 ± 0.846
7.454LeuSer: 7.454 ± 0.956
7.167LeuThr: 7.167 ± 0.844
6.021LeuVal: 6.021 ± 0.773
0.573LeuTrp: 0.573 ± 0.315
3.44LeuTyr: 3.44 ± 0.51
0.0LeuXaa: 0.0 ± 0.0
Met
2.007MetAla: 2.007 ± 1.41
0.86MetCys: 0.86 ± 0.636
2.007MetAsp: 2.007 ± 0.673
1.72MetGlu: 1.72 ± 0.388
0.86MetPhe: 0.86 ± 0.317
0.573MetGly: 0.573 ± 0.315
0.287MetHis: 0.287 ± 0.355
3.727MetIle: 3.727 ± 0.908
1.72MetLys: 1.72 ± 0.721
2.867MetLeu: 2.867 ± 0.637
0.86MetMet: 0.86 ± 0.317
1.433MetAsn: 1.433 ± 0.427
0.86MetPro: 0.86 ± 0.317
0.287MetGln: 0.287 ± 0.355
1.147MetArg: 1.147 ± 0.734
0.287MetSer: 0.287 ± 0.157
2.58MetThr: 2.58 ± 0.226
1.72MetVal: 1.72 ± 0.569
1.147MetTrp: 1.147 ± 0.418
0.573MetTyr: 0.573 ± 0.655
0.0MetXaa: 0.0 ± 0.0
Asn
1.72AsnAla: 1.72 ± 1.203
1.147AsnCys: 1.147 ± 0.364
1.433AsnAsp: 1.433 ± 0.519
3.154AsnGlu: 3.154 ± 0.921
2.867AsnPhe: 2.867 ± 0.917
1.147AsnGly: 1.147 ± 0.418
1.72AsnHis: 1.72 ± 0.653
5.447AsnIle: 5.447 ± 1.927
5.734AsnLys: 5.734 ± 0.809
8.888AsnLeu: 8.888 ± 1.084
2.294AsnMet: 2.294 ± 0.563
4.3AsnAsn: 4.3 ± 1.526
1.147AsnPro: 1.147 ± 0.782
2.007AsnGln: 2.007 ± 0.586
2.294AsnArg: 2.294 ± 0.876
4.014AsnSer: 4.014 ± 1.403
3.727AsnThr: 3.727 ± 0.734
3.154AsnVal: 3.154 ± 1.22
1.433AsnTrp: 1.433 ± 0.786
2.294AsnTyr: 2.294 ± 0.805
0.0AsnXaa: 0.0 ± 0.0
Pro
1.72ProAla: 1.72 ± 1.225
0.287ProCys: 0.287 ± 0.157
1.72ProAsp: 1.72 ± 0.893
2.58ProGlu: 2.58 ± 0.608
1.147ProPhe: 1.147 ± 0.629
0.573ProGly: 0.573 ± 0.315
1.72ProHis: 1.72 ± 0.643
3.154ProIle: 3.154 ± 0.793
3.154ProLys: 3.154 ± 0.793
2.294ProLeu: 2.294 ± 0.098
0.287ProMet: 0.287 ± 0.157
2.58ProAsn: 2.58 ± 0.536
1.147ProPro: 1.147 ± 0.629
0.573ProGln: 0.573 ± 0.298
2.294ProArg: 2.294 ± 0.54
2.007ProSer: 2.007 ± 0.696
2.58ProThr: 2.58 ± 1.054
1.433ProVal: 1.433 ± 0.92
0.287ProTrp: 0.287 ± 0.427
0.86ProTyr: 0.86 ± 0.361
0.0ProXaa: 0.0 ± 0.0
Gln
0.86GlnAla: 0.86 ± 0.32
0.573GlnCys: 0.573 ± 0.298
2.58GlnAsp: 2.58 ± 0.562
0.287GlnGlu: 0.287 ± 0.435
1.72GlnPhe: 1.72 ± 0.354
1.147GlnGly: 1.147 ± 0.734
0.86GlnHis: 0.86 ± 0.862
2.007GlnIle: 2.007 ± 0.436
3.154GlnLys: 3.154 ± 0.784
6.021GlnLeu: 6.021 ± 1.405
0.573GlnMet: 0.573 ± 0.367
0.86GlnAsn: 0.86 ± 0.317
1.147GlnPro: 1.147 ± 0.629
0.86GlnGln: 0.86 ± 0.862
0.86GlnArg: 0.86 ± 0.458
3.154GlnSer: 3.154 ± 0.867
0.86GlnThr: 0.86 ± 0.32
2.294GlnVal: 2.294 ± 0.92
0.0GlnTrp: 0.0 ± 0.0
1.433GlnTyr: 1.433 ± 0.644
0.0GlnXaa: 0.0 ± 0.0
Arg
1.433ArgAla: 1.433 ± 0.469
0.86ArgCys: 0.86 ± 0.759
2.58ArgAsp: 2.58 ± 1.458
4.587ArgGlu: 4.587 ± 1.318
2.58ArgPhe: 2.58 ± 0.562
3.44ArgGly: 3.44 ± 0.906
2.007ArgHis: 2.007 ± 0.586
2.294ArgIle: 2.294 ± 0.54
2.867ArgLys: 2.867 ± 0.691
4.3ArgLeu: 4.3 ± 0.805
0.86ArgMet: 0.86 ± 0.32
2.007ArgAsn: 2.007 ± 0.732
0.86ArgPro: 0.86 ± 0.472
1.433ArgGln: 1.433 ± 0.323
1.72ArgArg: 1.72 ± 0.798
3.154ArgSer: 3.154 ± 1.206
2.58ArgThr: 2.58 ± 0.596
2.867ArgVal: 2.867 ± 0.404
0.287ArgTrp: 0.287 ± 0.157
2.007ArgTyr: 2.007 ± 0.507
0.0ArgXaa: 0.0 ± 0.0
Ser
3.44SerAla: 3.44 ± 0.845
1.147SerCys: 1.147 ± 0.369
4.587SerAsp: 4.587 ± 0.645
4.3SerGlu: 4.3 ± 1.314
4.3SerPhe: 4.3 ± 1.145
3.727SerGly: 3.727 ± 0.841
1.72SerHis: 1.72 ± 0.329
7.167SerIle: 7.167 ± 1.166
3.44SerLys: 3.44 ± 1.214
7.454SerLeu: 7.454 ± 0.691
1.72SerMet: 1.72 ± 0.658
5.734SerAsn: 5.734 ± 1.699
3.154SerPro: 3.154 ± 0.701
2.294SerGln: 2.294 ± 0.601
4.014SerArg: 4.014 ± 1.465
5.447SerSer: 5.447 ± 0.762
4.3SerThr: 4.3 ± 0.829
3.727SerVal: 3.727 ± 0.835
1.147SerTrp: 1.147 ± 0.744
2.294SerTyr: 2.294 ± 0.805
0.0SerXaa: 0.0 ± 0.0
Thr
2.294ThrAla: 2.294 ± 0.541
1.433ThrCys: 1.433 ± 0.323
2.867ThrAsp: 2.867 ± 0.73
2.294ThrGlu: 2.294 ± 0.739
2.294ThrPhe: 2.294 ± 0.541
3.154ThrGly: 3.154 ± 0.563
1.433ThrHis: 1.433 ± 0.519
7.454ThrIle: 7.454 ± 1.938
3.44ThrLys: 3.44 ± 0.776
6.881ThrLeu: 6.881 ± 1.574
2.58ThrMet: 2.58 ± 1.068
3.154ThrAsn: 3.154 ± 1.107
2.007ThrPro: 2.007 ± 0.677
3.154ThrGln: 3.154 ± 0.784
2.58ThrArg: 2.58 ± 0.664
5.161ThrSer: 5.161 ± 0.964
3.44ThrThr: 3.44 ± 0.757
3.44ThrVal: 3.44 ± 0.889
1.433ThrTrp: 1.433 ± 0.469
1.72ThrTyr: 1.72 ± 0.48
0.0ThrXaa: 0.0 ± 0.0
Val
2.294ValAla: 2.294 ± 0.098
0.573ValCys: 0.573 ± 0.315
3.727ValAsp: 3.727 ± 1.431
3.44ValGlu: 3.44 ± 1.346
2.007ValPhe: 2.007 ± 0.732
3.727ValGly: 3.727 ± 0.312
1.433ValHis: 1.433 ± 0.276
6.307ValIle: 6.307 ± 1.006
3.727ValLys: 3.727 ± 0.7
5.447ValLeu: 5.447 ± 1.043
2.007ValMet: 2.007 ± 0.797
4.014ValAsn: 4.014 ± 0.584
2.007ValPro: 2.007 ± 0.452
1.147ValGln: 1.147 ± 0.418
2.294ValArg: 2.294 ± 1.005
5.161ValSer: 5.161 ± 1.629
2.58ValThr: 2.58 ± 0.226
4.874ValVal: 4.874 ± 0.622
0.0ValTrp: 0.0 ± 0.0
2.007ValTyr: 2.007 ± 0.802
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.573TrpCys: 0.573 ± 0.298
0.86TrpAsp: 0.86 ± 0.898
0.86TrpGlu: 0.86 ± 0.472
0.287TrpPhe: 0.287 ± 0.427
0.86TrpGly: 0.86 ± 0.32
0.0TrpHis: 0.0 ± 0.0
0.573TrpIle: 0.573 ± 0.315
0.86TrpLys: 0.86 ± 0.401
2.007TrpLeu: 2.007 ± 1.101
0.0TrpMet: 0.0 ± 0.0
0.573TrpAsn: 0.573 ± 0.655
0.287TrpPro: 0.287 ± 0.157
0.287TrpGln: 0.287 ± 0.435
1.147TrpArg: 1.147 ± 0.629
0.86TrpSer: 0.86 ± 0.472
0.287TrpThr: 0.287 ± 0.157
0.86TrpVal: 0.86 ± 0.472
0.0TrpTrp: 0.0 ± 0.0
0.287TrpTyr: 0.287 ± 0.157
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.86TyrAla: 0.86 ± 0.458
1.147TyrCys: 1.147 ± 0.835
3.154TyrAsp: 3.154 ± 0.786
1.72TyrGlu: 1.72 ± 0.388
0.86TyrPhe: 0.86 ± 0.361
2.58TyrGly: 2.58 ± 0.591
1.147TyrHis: 1.147 ± 0.364
4.014TyrIle: 4.014 ± 1.465
2.294TyrLys: 2.294 ± 0.95
3.44TyrLeu: 3.44 ± 0.863
0.573TyrMet: 0.573 ± 0.546
2.294TyrAsn: 2.294 ± 0.612
0.573TyrPro: 0.573 ± 0.367
1.147TyrGln: 1.147 ± 0.364
0.86TyrArg: 0.86 ± 0.472
2.867TyrSer: 2.867 ± 1.045
2.58TyrThr: 2.58 ± 0.536
1.433TyrVal: 1.433 ± 0.523
0.86TyrTrp: 0.86 ± 0.789
2.58TyrTyr: 2.58 ± 1.416
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3489 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski