Amino acid dipepetide frequency for Heterobasidion partitivirus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.587AlaAla: 13.587 ± 4.171
0.906AlaCys: 0.906 ± 0.498
5.435AlaAsp: 5.435 ± 0.871
3.623AlaGlu: 3.623 ± 0.934
1.812AlaPhe: 1.812 ± 0.062
2.717AlaGly: 2.717 ± 0.623
1.812AlaHis: 1.812 ± 0.062
7.246AlaIle: 7.246 ± 2.366
5.435AlaLys: 5.435 ± 0.187
5.435AlaLeu: 5.435 ± 1.245
3.623AlaMet: 3.623 ± 0.524
5.435AlaAsn: 5.435 ± 1.245
2.717AlaPro: 2.717 ± 1.681
3.623AlaGln: 3.623 ± 0.125
4.529AlaArg: 4.529 ± 0.373
6.341AlaSer: 6.341 ± 2.863
4.529AlaThr: 4.529 ± 0.373
5.435AlaVal: 5.435 ± 2.303
0.0AlaTrp: 0.0 ± 0.0
2.717AlaTyr: 2.717 ± 0.436
0.0AlaXaa: 0.0 ± 0.0
Cys
0.906CysAla: 0.906 ± 0.498
0.0CysCys: 0.0 ± 0.0
0.906CysAsp: 0.906 ± 0.56
0.0CysGlu: 0.0 ± 0.0
0.906CysPhe: 0.906 ± 0.498
0.906CysGly: 0.906 ± 0.56
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.906CysMet: 0.906 ± 0.498
0.0CysAsn: 0.0 ± 0.0
0.906CysPro: 0.906 ± 0.56
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.906CysSer: 0.906 ± 0.56
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.435AspAla: 5.435 ± 0.871
0.0AspCys: 0.0 ± 0.0
1.812AspAsp: 1.812 ± 0.996
2.717AspGlu: 2.717 ± 1.494
2.717AspPhe: 2.717 ± 0.436
1.812AspGly: 1.812 ± 0.062
2.717AspHis: 2.717 ± 1.494
2.717AspIle: 2.717 ± 0.436
1.812AspLys: 1.812 ± 0.996
6.341AspLeu: 6.341 ± 0.747
2.717AspMet: 2.717 ± 1.681
4.529AspAsn: 4.529 ± 1.743
3.623AspPro: 3.623 ± 0.934
1.812AspGln: 1.812 ± 1.12
0.0AspArg: 0.0 ± 0.0
4.529AspSer: 4.529 ± 0.373
3.623AspThr: 3.623 ± 0.125
1.812AspVal: 1.812 ± 1.12
1.812AspTrp: 1.812 ± 0.996
2.717AspTyr: 2.717 ± 0.436
0.0AspXaa: 0.0 ± 0.0
Glu
4.529GluAla: 4.529 ± 0.685
0.0GluCys: 0.0 ± 0.0
0.906GluAsp: 0.906 ± 0.498
3.623GluGlu: 3.623 ± 0.934
1.812GluPhe: 1.812 ± 0.062
0.906GluGly: 0.906 ± 0.56
0.906GluHis: 0.906 ± 0.498
4.529GluIle: 4.529 ± 1.432
0.906GluLys: 0.906 ± 0.498
0.0GluLeu: 0.0 ± 0.0
0.906GluMet: 0.906 ± 0.498
1.812GluAsn: 1.812 ± 0.996
1.812GluPro: 1.812 ± 0.996
1.812GluGln: 1.812 ± 0.062
3.623GluArg: 3.623 ± 0.934
4.529GluSer: 4.529 ± 1.743
0.906GluThr: 0.906 ± 0.498
0.906GluVal: 0.906 ± 0.498
0.0GluTrp: 0.0 ± 0.0
0.906GluTyr: 0.906 ± 0.498
0.0GluXaa: 0.0 ± 0.0
Phe
4.529PheAla: 4.529 ± 0.373
0.906PheCys: 0.906 ± 0.56
6.341PheAsp: 6.341 ± 2.427
1.812PheGlu: 1.812 ± 0.062
4.529PhePhe: 4.529 ± 0.685
5.435PheGly: 5.435 ± 0.187
0.906PheHis: 0.906 ± 0.498
2.717PheIle: 2.717 ± 0.623
0.906PheLys: 0.906 ± 0.498
7.246PheLeu: 7.246 ± 1.307
1.812PheMet: 1.812 ± 0.996
0.906PheAsn: 0.906 ± 0.498
2.717PhePro: 2.717 ± 1.494
4.529PheGln: 4.529 ± 0.373
4.529PheArg: 4.529 ± 0.373
4.529PheSer: 4.529 ± 0.373
3.623PheThr: 3.623 ± 1.183
3.623PheVal: 3.623 ± 0.934
2.717PheTrp: 2.717 ± 0.623
2.717PheTyr: 2.717 ± 0.623
0.0PheXaa: 0.0 ± 0.0
Gly
3.623GlyAla: 3.623 ± 1.183
0.0GlyCys: 0.0 ± 0.0
1.812GlyAsp: 1.812 ± 0.996
4.529GlyGlu: 4.529 ± 0.685
6.341GlyPhe: 6.341 ± 2.427
2.717GlyGly: 2.717 ± 0.623
1.812GlyHis: 1.812 ± 1.12
0.906GlyIle: 0.906 ± 0.56
1.812GlyLys: 1.812 ± 0.062
6.341GlyLeu: 6.341 ± 0.747
0.906GlyMet: 0.906 ± 0.498
1.812GlyAsn: 1.812 ± 0.062
2.717GlyPro: 2.717 ± 1.681
2.717GlyGln: 2.717 ± 1.681
1.812GlyArg: 1.812 ± 1.12
0.906GlySer: 0.906 ± 0.56
1.812GlyThr: 1.812 ± 0.062
2.717GlyVal: 2.717 ± 0.436
0.0GlyTrp: 0.0 ± 0.0
3.623GlyTyr: 3.623 ± 1.992
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.812HisAsp: 1.812 ± 0.996
0.906HisGlu: 0.906 ± 0.56
3.623HisPhe: 3.623 ± 1.992
0.906HisGly: 0.906 ± 0.498
0.906HisHis: 0.906 ± 0.498
0.906HisIle: 0.906 ± 0.56
0.0HisLys: 0.0 ± 0.0
1.812HisLeu: 1.812 ± 0.062
0.0HisMet: 0.0 ± 0.0
0.906HisAsn: 0.906 ± 0.56
4.529HisPro: 4.529 ± 1.432
0.906HisGln: 0.906 ± 0.498
2.717HisArg: 2.717 ± 0.623
0.906HisSer: 0.906 ± 0.56
1.812HisThr: 1.812 ± 0.062
2.717HisVal: 2.717 ± 1.494
0.0HisTrp: 0.0 ± 0.0
3.623HisTyr: 3.623 ± 1.992
0.0HisXaa: 0.0 ± 0.0
Ile
0.906IleAla: 0.906 ± 0.56
0.906IleCys: 0.906 ± 0.56
1.812IleAsp: 1.812 ± 1.12
2.717IleGlu: 2.717 ± 0.436
3.623IlePhe: 3.623 ± 0.934
0.0IleGly: 0.0 ± 0.0
0.906IleHis: 0.906 ± 0.498
1.812IleIle: 1.812 ± 0.996
3.623IleLys: 3.623 ± 0.934
3.623IleLeu: 3.623 ± 0.934
2.717IleMet: 2.717 ± 0.623
4.529IleAsn: 4.529 ± 1.743
7.246IlePro: 7.246 ± 0.809
1.812IleGln: 1.812 ± 0.996
4.529IleArg: 4.529 ± 2.49
4.529IleSer: 4.529 ± 1.743
4.529IleThr: 4.529 ± 1.743
1.812IleVal: 1.812 ± 0.062
0.0IleTrp: 0.0 ± 0.0
1.812IleTyr: 1.812 ± 0.996
0.0IleXaa: 0.0 ± 0.0
Lys
2.717LysAla: 2.717 ± 0.623
0.906LysCys: 0.906 ± 0.498
0.906LysAsp: 0.906 ± 0.56
0.0LysGlu: 0.0 ± 0.0
4.529LysPhe: 4.529 ± 0.685
2.717LysGly: 2.717 ± 0.436
0.906LysHis: 0.906 ± 0.498
2.717LysIle: 2.717 ± 1.494
1.812LysLys: 1.812 ± 0.062
3.623LysLeu: 3.623 ± 0.934
2.717LysMet: 2.717 ± 0.623
1.812LysAsn: 1.812 ± 0.062
1.812LysPro: 1.812 ± 0.062
2.717LysGln: 2.717 ± 1.681
3.623LysArg: 3.623 ± 1.992
3.623LysSer: 3.623 ± 0.125
4.529LysThr: 4.529 ± 2.49
0.906LysVal: 0.906 ± 0.498
0.0LysTrp: 0.0 ± 0.0
1.812LysTyr: 1.812 ± 1.12
0.0LysXaa: 0.0 ± 0.0
Leu
7.246LeuAla: 7.246 ± 2.366
0.906LeuCys: 0.906 ± 0.56
6.341LeuAsp: 6.341 ± 1.805
0.906LeuGlu: 0.906 ± 0.498
7.246LeuPhe: 7.246 ± 0.809
4.529LeuGly: 4.529 ± 0.373
1.812LeuHis: 1.812 ± 0.062
3.623LeuIle: 3.623 ± 1.183
5.435LeuLys: 5.435 ± 0.187
8.152LeuLeu: 8.152 ± 1.868
3.623LeuMet: 3.623 ± 1.992
5.435LeuAsn: 5.435 ± 0.187
3.623LeuPro: 3.623 ± 1.183
0.906LeuGln: 0.906 ± 0.56
7.246LeuArg: 7.246 ± 1.867
7.246LeuSer: 7.246 ± 0.249
2.717LeuThr: 2.717 ± 1.494
5.435LeuVal: 5.435 ± 2.303
2.717LeuTrp: 2.717 ± 1.494
1.812LeuTyr: 1.812 ± 0.996
0.0LeuXaa: 0.0 ± 0.0
Met
3.623MetAla: 3.623 ± 0.934
0.0MetCys: 0.0 ± 0.0
2.717MetAsp: 2.717 ± 0.623
0.0MetGlu: 0.0 ± 0.0
1.812MetPhe: 1.812 ± 0.062
0.906MetGly: 0.906 ± 0.498
1.812MetHis: 1.812 ± 0.062
0.906MetIle: 0.906 ± 0.56
4.529MetLys: 4.529 ± 0.373
1.812MetLeu: 1.812 ± 0.062
0.906MetMet: 0.906 ± 0.498
0.906MetAsn: 0.906 ± 0.56
2.717MetPro: 2.717 ± 0.436
0.906MetGln: 0.906 ± 0.498
0.906MetArg: 0.906 ± 0.56
3.623MetSer: 3.623 ± 1.183
1.812MetThr: 1.812 ± 1.12
0.906MetVal: 0.906 ± 0.498
0.906MetTrp: 0.906 ± 0.498
0.906MetTyr: 0.906 ± 0.56
0.0MetXaa: 0.0 ± 0.0
Asn
3.623AsnAla: 3.623 ± 2.241
0.0AsnCys: 0.0 ± 0.0
0.906AsnAsp: 0.906 ± 0.498
1.812AsnGlu: 1.812 ± 0.062
3.623AsnPhe: 3.623 ± 0.934
4.529AsnGly: 4.529 ± 0.373
0.0AsnHis: 0.0 ± 0.0
0.906AsnIle: 0.906 ± 0.56
1.812AsnLys: 1.812 ± 0.062
9.058AsnLeu: 9.058 ± 2.428
2.717AsnMet: 2.717 ± 0.974
3.623AsnAsn: 3.623 ± 0.125
3.623AsnPro: 3.623 ± 0.125
2.717AsnGln: 2.717 ± 0.623
0.906AsnArg: 0.906 ± 0.56
2.717AsnSer: 2.717 ± 1.494
3.623AsnThr: 3.623 ± 2.241
3.623AsnVal: 3.623 ± 0.125
2.717AsnTrp: 2.717 ± 1.494
1.812AsnTyr: 1.812 ± 0.996
0.0AsnXaa: 0.0 ± 0.0
Pro
7.246ProAla: 7.246 ± 1.307
0.0ProCys: 0.0 ± 0.0
4.529ProAsp: 4.529 ± 0.685
1.812ProGlu: 1.812 ± 0.062
7.246ProPhe: 7.246 ± 2.366
1.812ProGly: 1.812 ± 1.12
2.717ProHis: 2.717 ± 0.436
4.529ProIle: 4.529 ± 1.432
2.717ProLys: 2.717 ± 0.436
4.529ProLeu: 4.529 ± 0.373
1.812ProMet: 1.812 ± 0.062
4.529ProAsn: 4.529 ± 0.685
4.529ProPro: 4.529 ± 0.685
1.812ProGln: 1.812 ± 0.996
2.717ProArg: 2.717 ± 1.494
1.812ProSer: 1.812 ± 0.062
5.435ProThr: 5.435 ± 0.871
5.435ProVal: 5.435 ± 0.187
0.0ProTrp: 0.0 ± 0.0
3.623ProTyr: 3.623 ± 0.125
0.0ProXaa: 0.0 ± 0.0
Gln
2.717GlnAla: 2.717 ± 0.623
0.906GlnCys: 0.906 ± 0.498
0.0GlnAsp: 0.0 ± 0.0
0.906GlnGlu: 0.906 ± 0.498
2.717GlnPhe: 2.717 ± 0.623
5.435GlnGly: 5.435 ± 1.245
0.906GlnHis: 0.906 ± 0.498
2.717GlnIle: 2.717 ± 0.623
3.623GlnLys: 3.623 ± 0.125
1.812GlnLeu: 1.812 ± 0.996
0.906GlnMet: 0.906 ± 0.56
1.812GlnAsn: 1.812 ± 1.12
0.0GlnPro: 0.0 ± 0.0
1.812GlnGln: 1.812 ± 1.12
5.435GlnArg: 5.435 ± 1.929
0.906GlnSer: 0.906 ± 0.56
2.717GlnThr: 2.717 ± 0.436
2.717GlnVal: 2.717 ± 0.436
0.906GlnTrp: 0.906 ± 0.56
2.717GlnTyr: 2.717 ± 1.681
0.0GlnXaa: 0.0 ± 0.0
Arg
4.529ArgAla: 4.529 ± 1.432
0.0ArgCys: 0.0 ± 0.0
5.435ArgAsp: 5.435 ± 1.929
0.906ArgGlu: 0.906 ± 0.498
2.717ArgPhe: 2.717 ± 0.623
0.906ArgGly: 0.906 ± 0.56
4.529ArgHis: 4.529 ± 1.432
2.717ArgIle: 2.717 ± 0.436
1.812ArgLys: 1.812 ± 0.062
6.341ArgLeu: 6.341 ± 0.311
0.906ArgMet: 0.906 ± 0.498
1.812ArgAsn: 1.812 ± 0.062
5.435ArgPro: 5.435 ± 0.871
1.812ArgGln: 1.812 ± 0.062
0.906ArgArg: 0.906 ± 0.498
0.906ArgSer: 0.906 ± 0.498
3.623ArgThr: 3.623 ± 0.934
5.435ArgVal: 5.435 ± 0.187
0.906ArgTrp: 0.906 ± 0.498
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
8.152SerAla: 8.152 ± 1.868
0.906SerCys: 0.906 ± 0.56
2.717SerAsp: 2.717 ± 0.436
2.717SerGlu: 2.717 ± 0.436
2.717SerPhe: 2.717 ± 0.623
4.529SerGly: 4.529 ± 0.685
0.906SerHis: 0.906 ± 0.498
6.341SerIle: 6.341 ± 0.747
2.717SerLys: 2.717 ± 0.623
6.341SerLeu: 6.341 ± 0.747
0.906SerMet: 0.906 ± 0.56
3.623SerAsn: 3.623 ± 0.934
5.435SerPro: 5.435 ± 1.245
2.717SerGln: 2.717 ± 1.681
0.906SerArg: 0.906 ± 0.56
2.717SerSer: 2.717 ± 1.681
3.623SerThr: 3.623 ± 1.183
2.717SerVal: 2.717 ± 0.436
2.717SerTrp: 2.717 ± 1.681
0.906SerTyr: 0.906 ± 0.498
0.0SerXaa: 0.0 ± 0.0
Thr
4.529ThrAla: 4.529 ± 0.373
0.0ThrCys: 0.0 ± 0.0
6.341ThrAsp: 6.341 ± 0.311
3.623ThrGlu: 3.623 ± 0.125
1.812ThrPhe: 1.812 ± 0.062
3.623ThrGly: 3.623 ± 0.125
0.906ThrHis: 0.906 ± 0.56
3.623ThrIle: 3.623 ± 1.992
0.906ThrLys: 0.906 ± 0.56
6.341ThrLeu: 6.341 ± 1.369
1.812ThrMet: 1.812 ± 1.12
2.717ThrAsn: 2.717 ± 0.623
3.623ThrPro: 3.623 ± 1.183
2.717ThrGln: 2.717 ± 0.436
3.623ThrArg: 3.623 ± 0.125
4.529ThrSer: 4.529 ± 1.743
1.812ThrThr: 1.812 ± 1.12
3.623ThrVal: 3.623 ± 1.992
0.0ThrTrp: 0.0 ± 0.0
1.812ThrTyr: 1.812 ± 0.996
0.0ThrXaa: 0.0 ± 0.0
Val
5.435ValAla: 5.435 ± 1.245
0.0ValCys: 0.0 ± 0.0
3.623ValAsp: 3.623 ± 1.183
2.717ValGlu: 2.717 ± 1.494
2.717ValPhe: 2.717 ± 0.623
0.906ValGly: 0.906 ± 0.498
1.812ValHis: 1.812 ± 0.062
0.906ValIle: 0.906 ± 0.498
0.906ValLys: 0.906 ± 0.498
5.435ValLeu: 5.435 ± 0.871
0.906ValMet: 0.906 ± 0.498
2.717ValAsn: 2.717 ± 0.623
8.152ValPro: 8.152 ± 1.868
3.623ValGln: 3.623 ± 0.934
1.812ValArg: 1.812 ± 1.12
1.812ValSer: 1.812 ± 0.062
4.529ValThr: 4.529 ± 2.49
0.906ValVal: 0.906 ± 0.56
0.906ValTrp: 0.906 ± 0.498
3.623ValTyr: 3.623 ± 0.934
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.906TrpGly: 0.906 ± 0.498
0.906TrpHis: 0.906 ± 0.498
0.0TrpIle: 0.0 ± 0.0
0.906TrpLys: 0.906 ± 0.498
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.717TrpAsn: 2.717 ± 0.436
1.812TrpPro: 1.812 ± 0.996
1.812TrpGln: 1.812 ± 0.062
0.906TrpArg: 0.906 ± 0.498
1.812TrpSer: 1.812 ± 0.062
1.812TrpThr: 1.812 ± 1.12
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.717TrpTyr: 2.717 ± 0.436
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.623TyrAla: 3.623 ± 1.183
0.0TyrCys: 0.0 ± 0.0
0.906TyrAsp: 0.906 ± 0.56
0.0TyrGlu: 0.0 ± 0.0
4.529TyrPhe: 4.529 ± 1.432
2.717TyrGly: 2.717 ± 0.623
1.812TyrHis: 1.812 ± 0.996
3.623TyrIle: 3.623 ± 0.934
2.717TyrLys: 2.717 ± 0.436
2.717TyrLeu: 2.717 ± 0.436
0.906TyrMet: 0.906 ± 0.56
3.623TyrAsn: 3.623 ± 1.992
1.812TyrPro: 1.812 ± 0.996
0.906TyrGln: 0.906 ± 0.498
0.906TyrArg: 0.906 ± 0.498
5.435TyrSer: 5.435 ± 0.187
0.906TyrThr: 0.906 ± 0.498
2.717TyrVal: 2.717 ± 1.494
0.0TyrTrp: 0.0 ± 0.0
5.435TyrTyr: 5.435 ± 0.187
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1105 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski