Amino acid dipepetide frequency for Glaciihabitans arcticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.189AlaAla: 18.189 ± 0.244	0.533AlaCys: 0.533 ± 0.025	7.16AlaAsp: 7.16 ± 0.097	7.479AlaGlu: 7.479 ± 0.127	3.89AlaPhe: 3.89 ± 0.07	11.19AlaGly: 11.19 ± 0.139	2.106AlaHis: 2.106 ± 0.051	6.55AlaIle: 6.55 ± 0.094	3.074AlaLys: 3.074 ± 0.067	13.529AlaLeu: 13.529 ± 0.169	2.333AlaMet: 2.333 ± 0.057	2.815AlaAsn: 2.815 ± 0.059	6.084AlaPro: 6.084 ± 0.129	3.424AlaGln: 3.424 ± 0.06	7.671AlaArg: 7.671 ± 0.13	7.823AlaSer: 7.823 ± 0.09	8.269AlaThr: 8.269 ± 0.177	10.754AlaVal: 10.754 ± 0.132	1.726AlaTrp: 1.726 ± 0.044	2.222AlaTyr: 2.222 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.567CysAla: 0.567 ± 0.029	0.05CysCys: 0.05 ± 0.007	0.276CysAsp: 0.276 ± 0.018	0.246CysGlu: 0.246 ± 0.016	0.148CysPhe: 0.148 ± 0.014	0.479CysGly: 0.479 ± 0.025	0.093CysHis: 0.093 ± 0.011	0.181CysIle: 0.181 ± 0.013	0.054CysLys: 0.054 ± 0.008	0.397CysLeu: 0.397 ± 0.017	0.071CysMet: 0.071 ± 0.009	0.095CysAsn: 0.095 ± 0.01	0.237CysPro: 0.237 ± 0.015	0.1CysGln: 0.1 ± 0.011	0.221CysArg: 0.221 ± 0.016	0.377CysSer: 0.377 ± 0.022	0.326CysThr: 0.326 ± 0.02	0.377CysVal: 0.377 ± 0.022	0.069CysTrp: 0.069 ± 0.008	0.107CysTyr: 0.107 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.653AspAla: 7.653 ± 0.086	0.273AspCys: 0.273 ± 0.018	3.978AspAsp: 3.978 ± 0.078	3.977AspGlu: 3.977 ± 0.074	2.016AspPhe: 2.016 ± 0.053	5.643AspGly: 5.643 ± 0.098	1.095AspHis: 1.095 ± 0.036	2.51AspIle: 2.51 ± 0.056	1.212AspLys: 1.212 ± 0.04	6.069AspLeu: 6.069 ± 0.085	0.789AspMet: 0.789 ± 0.027	1.269AspAsn: 1.269 ± 0.046	3.625AspPro: 3.625 ± 0.064	1.49AspGln: 1.49 ± 0.035	3.745AspArg: 3.745 ± 0.071	3.25AspSer: 3.25 ± 0.065	3.073AspThr: 3.073 ± 0.06	5.283AspVal: 5.283 ± 0.085	0.987AspTrp: 0.987 ± 0.035	1.478AspTyr: 1.478 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.543GluAla: 6.543 ± 0.101	0.227GluCys: 0.227 ± 0.018	2.593GluAsp: 2.593 ± 0.049	2.884GluGlu: 2.884 ± 0.077	2.021GluPhe: 2.021 ± 0.048	4.006GluGly: 4.006 ± 0.062	1.263GluHis: 1.263 ± 0.042	2.982GluIle: 2.982 ± 0.058	1.739GluLys: 1.739 ± 0.052	6.985GluLeu: 6.985 ± 0.11	0.913GluMet: 0.913 ± 0.027	1.427GluAsn: 1.427 ± 0.036	3.072GluPro: 3.072 ± 0.076	2.132GluGln: 2.132 ± 0.051	4.358GluArg: 4.358 ± 0.089	3.293GluSer: 3.293 ± 0.057	3.157GluThr: 3.157 ± 0.07	4.333GluVal: 4.333 ± 0.081	0.892GluTrp: 0.892 ± 0.035	1.257GluTyr: 1.257 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.459PheAla: 4.459 ± 0.074	0.175PheCys: 0.175 ± 0.014	2.466PheAsp: 2.466 ± 0.05	2.103PheGlu: 2.103 ± 0.047	1.177PhePhe: 1.177 ± 0.042	3.718PheGly: 3.718 ± 0.064	0.492PheHis: 0.492 ± 0.022	1.452PheIle: 1.452 ± 0.051	0.536PheLys: 0.536 ± 0.026	3.002PheLeu: 3.002 ± 0.063	0.481PheMet: 0.481 ± 0.023	0.81PheAsn: 0.81 ± 0.034	1.461PhePro: 1.461 ± 0.037	0.785PheGln: 0.785 ± 0.029	1.701PheArg: 1.701 ± 0.046	2.148PheSer: 2.148 ± 0.049	2.447PheThr: 2.447 ± 0.058	3.109PheVal: 3.109 ± 0.063	0.51PheTrp: 0.51 ± 0.022	0.736PheTyr: 0.736 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	10.08GlyAla: 10.08 ± 0.111	0.579GlyCys: 0.579 ± 0.029	5.063GlyAsp: 5.063 ± 0.11	4.869GlyGlu: 4.869 ± 0.081	3.589GlyPhe: 3.589 ± 0.07	7.581GlyGly: 7.581 ± 0.174	1.635GlyHis: 1.635 ± 0.041	5.034GlyIle: 5.034 ± 0.076	2.55GlyLys: 2.55 ± 0.062	9.003GlyLeu: 9.003 ± 0.109	1.75GlyMet: 1.75 ± 0.046	2.167GlyAsn: 2.167 ± 0.079	3.466GlyPro: 3.466 ± 0.064	2.422GlyGln: 2.422 ± 0.056	5.146GlyArg: 5.146 ± 0.081	6.11GlySer: 6.11 ± 0.113	5.982GlyThr: 5.982 ± 0.142	7.678GlyVal: 7.678 ± 0.112	1.585GlyTrp: 1.585 ± 0.041	2.273GlyTyr: 2.273 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.874HisAla: 1.874 ± 0.044	0.094HisCys: 0.094 ± 0.009	1.109HisAsp: 1.109 ± 0.036	0.973HisGlu: 0.973 ± 0.034	0.584HisPhe: 0.584 ± 0.026	1.678HisGly: 1.678 ± 0.042	0.433HisHis: 0.433 ± 0.025	0.716HisIle: 0.716 ± 0.032	0.305HisLys: 0.305 ± 0.016	1.816HisLeu: 1.816 ± 0.045	0.273HisMet: 0.273 ± 0.015	0.48HisAsn: 0.48 ± 0.022	1.308HisPro: 1.308 ± 0.034	0.446HisGln: 0.446 ± 0.021	1.235HisArg: 1.235 ± 0.037	1.126HisSer: 1.126 ± 0.035	0.957HisThr: 0.957 ± 0.034	1.38HisVal: 1.38 ± 0.039	0.285HisTrp: 0.285 ± 0.016	0.411HisTyr: 0.411 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.199IleAla: 7.199 ± 0.103	0.224IleCys: 0.224 ± 0.016	3.608IleAsp: 3.608 ± 0.063	3.149IleGlu: 3.149 ± 0.059	1.45IlePhe: 1.45 ± 0.046	4.829IleGly: 4.829 ± 0.083	0.706IleHis: 0.706 ± 0.027	2.218IleIle: 2.218 ± 0.057	1.079IleLys: 1.079 ± 0.034	4.22IleLeu: 4.22 ± 0.075	0.635IleMet: 0.635 ± 0.023	1.178IleAsn: 1.178 ± 0.036	2.696IlePro: 2.696 ± 0.062	1.098IleGln: 1.098 ± 0.033	2.732IleArg: 2.732 ± 0.053	2.931IleSer: 2.931 ± 0.057	3.49IleThr: 3.49 ± 0.08	4.954IleVal: 4.954 ± 0.079	0.537IleTrp: 0.537 ± 0.026	0.865IleTyr: 0.865 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.914LysAla: 2.914 ± 0.058	0.065LysCys: 0.065 ± 0.008	1.314LysAsp: 1.314 ± 0.046	1.057LysGlu: 1.057 ± 0.037	0.671LysPhe: 0.671 ± 0.031	1.827LysGly: 1.827 ± 0.05	0.503LysHis: 0.503 ± 0.024	1.137LysIle: 1.137 ± 0.037	1.069LysLys: 1.069 ± 0.045	2.455LysLeu: 2.455 ± 0.059	0.438LysMet: 0.438 ± 0.026	0.709LysAsn: 0.709 ± 0.032	1.506LysPro: 1.506 ± 0.042	0.825LysGln: 0.825 ± 0.032	1.76LysArg: 1.76 ± 0.051	1.43LysSer: 1.43 ± 0.042	1.671LysThr: 1.671 ± 0.049	1.983LysVal: 1.983 ± 0.054	0.297LysTrp: 0.297 ± 0.02	0.584LysTyr: 0.584 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	14.594LeuAla: 14.594 ± 0.187	0.444LeuCys: 0.444 ± 0.02	6.631LeuAsp: 6.631 ± 0.088	5.803LeuGlu: 5.803 ± 0.1	3.148LeuPhe: 3.148 ± 0.066	9.528LeuGly: 9.528 ± 0.138	1.72LeuHis: 1.72 ± 0.045	4.66LeuIle: 4.66 ± 0.081	2.149LeuLys: 2.149 ± 0.048	10.588LeuLeu: 10.588 ± 0.181	1.538LeuMet: 1.538 ± 0.041	2.052LeuAsn: 2.052 ± 0.046	5.461LeuPro: 5.461 ± 0.087	2.432LeuGln: 2.432 ± 0.05	6.649LeuArg: 6.649 ± 0.098	6.531LeuSer: 6.531 ± 0.094	6.476LeuThr: 6.476 ± 0.112	9.827LeuVal: 9.827 ± 0.133	1.217LeuTrp: 1.217 ± 0.041	1.71LeuTyr: 1.71 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	1.881MetAla: 1.881 ± 0.047	0.066MetCys: 0.066 ± 0.009	0.766MetAsp: 0.766 ± 0.026	0.613MetGlu: 0.613 ± 0.025	0.533MetPhe: 0.533 ± 0.022	1.2MetGly: 1.2 ± 0.037	0.282MetHis: 0.282 ± 0.016	0.837MetIle: 0.837 ± 0.032	0.487MetLys: 0.487 ± 0.022	1.714MetLeu: 1.714 ± 0.046	0.262MetMet: 0.262 ± 0.018	0.5MetAsn: 0.5 ± 0.023	0.989MetPro: 0.989 ± 0.033	0.499MetGln: 0.499 ± 0.021	1.157MetArg: 1.157 ± 0.036	1.36MetSer: 1.36 ± 0.038	1.659MetThr: 1.659 ± 0.036	1.287MetVal: 1.287 ± 0.032	0.18MetTrp: 0.18 ± 0.014	0.247MetTyr: 0.247 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.778AsnAla: 2.778 ± 0.055	0.121AsnCys: 0.121 ± 0.01	1.37AsnAsp: 1.37 ± 0.038	1.273AsnGlu: 1.273 ± 0.034	0.808AsnPhe: 0.808 ± 0.028	2.407AsnGly: 2.407 ± 0.067	0.426AsnHis: 0.426 ± 0.02	1.065AsnIle: 1.065 ± 0.034	0.566AsnLys: 0.566 ± 0.028	2.247AsnLeu: 2.247 ± 0.045	0.376AsnMet: 0.376 ± 0.022	0.725AsnAsn: 0.725 ± 0.037	1.797AsnPro: 1.797 ± 0.045	0.664AsnGln: 0.664 ± 0.028	1.384AsnArg: 1.384 ± 0.04	1.379AsnSer: 1.379 ± 0.042	1.443AsnThr: 1.443 ± 0.088	2.08AsnVal: 2.08 ± 0.075	0.393AsnTrp: 0.393 ± 0.02	0.63AsnTyr: 0.63 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	6.669ProAla: 6.669 ± 0.119	0.158ProCys: 0.158 ± 0.014	3.364ProAsp: 3.364 ± 0.061	3.603ProGlu: 3.603 ± 0.07	1.724ProPhe: 1.724 ± 0.047	4.829ProGly: 4.829 ± 0.089	0.888ProHis: 0.888 ± 0.03	2.463ProIle: 2.463 ± 0.05	1.236ProLys: 1.236 ± 0.04	4.832ProLeu: 4.832 ± 0.072	0.8ProMet: 0.8 ± 0.031	1.287ProAsn: 1.287 ± 0.048	2.063ProPro: 2.063 ± 0.069	1.433ProGln: 1.433 ± 0.042	2.923ProArg: 2.923 ± 0.066	3.251ProSer: 3.251 ± 0.06	3.629ProThr: 3.629 ± 0.085	4.951ProVal: 4.951 ± 0.086	0.814ProTrp: 0.814 ± 0.032	0.995ProTyr: 0.995 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.057GlnAla: 3.057 ± 0.057	0.102GlnCys: 0.102 ± 0.01	1.17GlnAsp: 1.17 ± 0.038	1.118GlnGlu: 1.118 ± 0.038	0.991GlnPhe: 0.991 ± 0.031	1.958GlnGly: 1.958 ± 0.046	0.571GlnHis: 0.571 ± 0.027	1.307GlnIle: 1.307 ± 0.036	0.772GlnLys: 0.772 ± 0.029	3.524GlnLeu: 3.524 ± 0.061	0.454GlnMet: 0.454 ± 0.022	0.709GlnAsn: 0.709 ± 0.026	1.547GlnPro: 1.547 ± 0.047	1.065GlnGln: 1.065 ± 0.036	2.123GlnArg: 2.123 ± 0.048	1.573GlnSer: 1.573 ± 0.041	1.555GlnThr: 1.555 ± 0.037	2.361GlnVal: 2.361 ± 0.045	0.493GlnTrp: 0.493 ± 0.028	0.652GlnTyr: 0.652 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.34ArgAla: 7.34 ± 0.117	0.237ArgCys: 0.237 ± 0.017	3.801ArgAsp: 3.801 ± 0.076	3.817ArgGlu: 3.817 ± 0.08	2.346ArgPhe: 2.346 ± 0.048	4.768ArgGly: 4.768 ± 0.076	1.247ArgHis: 1.247 ± 0.042	3.37ArgIle: 3.37 ± 0.064	1.511ArgLys: 1.511 ± 0.047	6.403ArgLeu: 6.403 ± 0.1	1.395ArgMet: 1.395 ± 0.038	1.502ArgAsn: 1.502 ± 0.05	2.962ArgPro: 2.962 ± 0.066	1.887ArgGln: 1.887 ± 0.047	4.806ArgArg: 4.806 ± 0.113	4.093ArgSer: 4.093 ± 0.08	3.693ArgThr: 3.693 ± 0.07	5.48ArgVal: 5.48 ± 0.089	0.992ArgTrp: 0.992 ± 0.035	1.46ArgTyr: 1.46 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	7.581SerAla: 7.581 ± 0.107	0.283SerCys: 0.283 ± 0.017	3.517SerAsp: 3.517 ± 0.062	3.026SerGlu: 3.026 ± 0.061	2.223SerPhe: 2.223 ± 0.044	6.34SerGly: 6.34 ± 0.111	1.016SerHis: 1.016 ± 0.03	3.228SerIle: 3.228 ± 0.062	1.499SerLys: 1.499 ± 0.041	6.244SerLeu: 6.244 ± 0.085	1.152SerMet: 1.152 ± 0.033	1.564SerAsn: 1.564 ± 0.046	3.25SerPro: 3.25 ± 0.057	1.562SerGln: 1.562 ± 0.042	3.935SerArg: 3.935 ± 0.078	4.204SerSer: 4.204 ± 0.078	4.454SerThr: 4.454 ± 0.089	5.536SerVal: 5.536 ± 0.087	0.998SerTrp: 0.998 ± 0.033	1.541SerTyr: 1.541 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	8.322ThrAla: 8.322 ± 0.178	0.248ThrCys: 0.248 ± 0.019	3.614ThrAsp: 3.614 ± 0.067	3.345ThrGlu: 3.345 ± 0.056	2.167ThrPhe: 2.167 ± 0.055	6.278ThrGly: 6.278 ± 0.172	1.013ThrHis: 1.013 ± 0.031	3.576ThrIle: 3.576 ± 0.083	1.557ThrLys: 1.557 ± 0.047	6.583ThrLeu: 6.583 ± 0.123	0.886ThrMet: 0.886 ± 0.033	1.546ThrAsn: 1.546 ± 0.064	4.121ThrPro: 4.121 ± 0.078	1.501ThrGln: 1.501 ± 0.042	3.735ThrArg: 3.735 ± 0.063	4.107ThrSer: 4.107 ± 0.081	4.378ThrThr: 4.378 ± 0.118	6.532ThrVal: 6.532 ± 0.144	0.92ThrTrp: 0.92 ± 0.034	1.355ThrTyr: 1.355 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	11.328ValAla: 11.328 ± 0.116	0.399ValCys: 0.399 ± 0.022	5.569ValAsp: 5.569 ± 0.073	4.923ValGlu: 4.923 ± 0.079	2.895ValPhe: 2.895 ± 0.059	7.337ValGly: 7.337 ± 0.092	1.442ValHis: 1.442 ± 0.034	5.035ValIle: 5.035 ± 0.078	1.919ValLys: 1.919 ± 0.053	9.371ValLeu: 9.371 ± 0.128	1.395ValMet: 1.395 ± 0.038	2.046ValAsn: 2.046 ± 0.051	4.483ValPro: 4.483 ± 0.078	2.144ValGln: 2.144 ± 0.042	5.287ValArg: 5.287 ± 0.091	5.768ValSer: 5.768 ± 0.091	6.703ValThr: 6.703 ± 0.173	8.371ValVal: 8.371 ± 0.11	1.071ValTrp: 1.071 ± 0.031	1.606ValTyr: 1.606 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.492TrpAla: 1.492 ± 0.048	0.076TrpCys: 0.076 ± 0.008	0.76TrpAsp: 0.76 ± 0.028	0.643TrpGlu: 0.643 ± 0.027	0.595TrpPhe: 0.595 ± 0.027	1.006TrpGly: 1.006 ± 0.035	0.28TrpHis: 0.28 ± 0.017	0.729TrpIle: 0.729 ± 0.027	0.421TrpLys: 0.421 ± 0.022	1.824TrpLeu: 1.824 ± 0.05	0.335TrpMet: 0.335 ± 0.019	0.489TrpAsn: 0.489 ± 0.021	0.725TrpPro: 0.725 ± 0.039	0.576TrpGln: 0.576 ± 0.025	1.004TrpArg: 1.004 ± 0.037	0.947TrpSer: 0.947 ± 0.031	0.936TrpThr: 0.936 ± 0.032	1.139TrpVal: 1.139 ± 0.036	0.344TrpTrp: 0.344 ± 0.021	0.332TrpTyr: 0.332 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.299TyrAla: 2.299 ± 0.05	0.115TyrCys: 0.115 ± 0.01	1.287TyrAsp: 1.287 ± 0.04	1.175TyrGlu: 1.175 ± 0.033	0.792TyrPhe: 0.792 ± 0.028	1.957TyrGly: 1.957 ± 0.055	0.272TyrHis: 0.272 ± 0.019	0.749TyrIle: 0.749 ± 0.031	0.481TyrLys: 0.481 ± 0.024	2.353TyrLeu: 2.353 ± 0.058	0.241TyrMet: 0.241 ± 0.015	0.561TyrAsn: 0.561 ± 0.027	1.061TyrPro: 1.061 ± 0.037	0.619TyrGln: 0.619 ± 0.03	1.539TyrArg: 1.539 ± 0.045	1.453TyrSer: 1.453 ± 0.045	1.485TyrThr: 1.485 ± 0.069	1.679TyrVal: 1.679 ± 0.045	0.342TyrTrp: 0.342 ± 0.019	0.513TyrTyr: 0.513 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2984 proteins (981908 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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