Amino acid dipepetide frequency for Rattus norvegicus papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.4AlaAla: 6.4 ± 2.836
0.533AlaCys: 0.533 ± 0.439
2.667AlaAsp: 2.667 ± 1.521
4.267AlaGlu: 4.267 ± 2.523
2.667AlaPhe: 2.667 ± 1.145
4.8AlaGly: 4.8 ± 2.769
0.0AlaHis: 0.0 ± 0.0
3.2AlaIle: 3.2 ± 1.38
3.2AlaLys: 3.2 ± 0.501
2.133AlaLeu: 2.133 ± 1.332
1.6AlaMet: 1.6 ± 0.796
1.6AlaAsn: 1.6 ± 0.796
1.6AlaPro: 1.6 ± 0.762
0.533AlaGln: 0.533 ± 0.474
6.4AlaArg: 6.4 ± 1.002
4.8AlaSer: 4.8 ± 1.034
6.933AlaThr: 6.933 ± 2.102
6.4AlaVal: 6.4 ± 0.937
0.533AlaTrp: 0.533 ± 0.474
2.133AlaTyr: 2.133 ± 1.149
0.0AlaXaa: 0.0 ± 0.0
Cys
2.133CysAla: 2.133 ± 2.826
0.533CysCys: 0.533 ± 0.439
2.667CysAsp: 2.667 ± 2.013
0.0CysGlu: 0.0 ± 0.0
1.067CysPhe: 1.067 ± 0.452
0.533CysGly: 0.533 ± 0.439
0.533CysHis: 0.533 ± 0.439
1.6CysIle: 1.6 ± 0.666
2.133CysLys: 2.133 ± 0.974
2.133CysLeu: 2.133 ± 0.815
0.533CysMet: 0.533 ± 0.439
0.533CysAsn: 0.533 ± 0.439
2.667CysPro: 2.667 ± 1.984
0.0CysGln: 0.0 ± 0.0
1.6CysArg: 1.6 ± 2.225
4.8CysSer: 4.8 ± 1.891
3.2CysThr: 3.2 ± 1.509
0.533CysVal: 0.533 ± 0.474
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.133AspAla: 2.133 ± 0.577
2.133AspCys: 2.133 ± 0.55
1.6AspAsp: 1.6 ± 0.796
4.8AspGlu: 4.8 ± 2.041
1.067AspPhe: 1.067 ± 0.452
5.333AspGly: 5.333 ± 1.039
1.067AspHis: 1.067 ± 0.837
1.067AspIle: 1.067 ± 0.452
1.6AspLys: 1.6 ± 0.306
6.933AspLeu: 6.933 ± 0.655
0.533AspMet: 0.533 ± 0.474
1.6AspAsn: 1.6 ± 0.815
5.333AspPro: 5.333 ± 1.892
1.067AspGln: 1.067 ± 0.52
5.333AspArg: 5.333 ± 0.897
3.2AspSer: 3.2 ± 0.895
2.667AspThr: 2.667 ± 0.839
2.667AspVal: 2.667 ± 1.249
1.6AspTrp: 1.6 ± 1.317
2.133AspTyr: 2.133 ± 0.855
0.0AspXaa: 0.0 ± 0.0
Glu
4.267GluAla: 4.267 ± 1.5
1.6GluCys: 1.6 ± 1.237
4.8GluAsp: 4.8 ± 1.549
6.933GluGlu: 6.933 ± 2.27
1.6GluPhe: 1.6 ± 1.422
4.8GluGly: 4.8 ± 0.495
0.0GluHis: 0.0 ± 0.0
0.533GluIle: 0.533 ± 0.474
3.2GluLys: 3.2 ± 1.197
3.2GluLeu: 3.2 ± 1.851
1.6GluMet: 1.6 ± 0.796
1.6GluAsn: 1.6 ± 0.903
3.733GluPro: 3.733 ± 2.299
4.267GluGln: 4.267 ± 1.24
4.8GluArg: 4.8 ± 1.204
3.733GluSer: 3.733 ± 1.252
5.867GluThr: 5.867 ± 0.65
5.333GluVal: 5.333 ± 0.858
0.0GluTrp: 0.0 ± 0.0
2.133GluTyr: 2.133 ± 0.577
0.0GluXaa: 0.0 ± 0.0
Phe
1.067PheAla: 1.067 ± 0.452
1.6PheCys: 1.6 ± 1.433
3.2PheAsp: 3.2 ± 0.723
3.733PheGlu: 3.733 ± 1.8
2.133PhePhe: 2.133 ± 0.651
1.6PheGly: 1.6 ± 1.163
0.533PheHis: 0.533 ± 0.439
2.133PheIle: 2.133 ± 1.254
0.533PheLys: 0.533 ± 0.439
3.733PheLeu: 3.733 ± 1.8
0.0PheMet: 0.0 ± 0.0
2.667PheAsn: 2.667 ± 1.345
0.0PhePro: 0.0 ± 0.0
2.133PheGln: 2.133 ± 0.651
2.133PheArg: 2.133 ± 0.651
2.133PheSer: 2.133 ± 0.651
1.067PheThr: 1.067 ± 0.757
2.667PheVal: 2.667 ± 0.748
1.067PheTrp: 1.067 ± 0.452
2.133PheTyr: 2.133 ± 0.651
0.0PheXaa: 0.0 ± 0.0
Gly
1.6GlyAla: 1.6 ± 0.815
1.067GlyCys: 1.067 ± 0.452
6.4GlyAsp: 6.4 ± 1.48
4.8GlyGlu: 4.8 ± 2.054
2.133GlyPhe: 2.133 ± 0.903
3.2GlyGly: 3.2 ± 1.971
3.2GlyHis: 3.2 ± 0.998
3.733GlyIle: 3.733 ± 0.951
2.667GlyLys: 2.667 ± 0.562
3.2GlyLeu: 3.2 ± 2.358
2.133GlyMet: 2.133 ± 1.188
5.333GlyAsn: 5.333 ± 1.963
5.867GlyPro: 5.867 ± 2.935
3.733GlyGln: 3.733 ± 2.241
4.8GlyArg: 4.8 ± 1.432
2.667GlySer: 2.667 ± 0.731
4.267GlyThr: 4.267 ± 0.864
4.8GlyVal: 4.8 ± 0.924
0.533GlyTrp: 0.533 ± 0.439
1.067GlyTyr: 1.067 ± 0.46
0.0GlyXaa: 0.0 ± 0.0
His
0.533HisAla: 0.533 ± 0.418
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.533HisGlu: 0.533 ± 0.439
1.6HisPhe: 1.6 ± 0.815
1.6HisGly: 1.6 ± 0.967
0.0HisHis: 0.0 ± 0.0
1.6HisIle: 1.6 ± 0.754
0.0HisLys: 0.0 ± 0.0
1.067HisLeu: 1.067 ± 0.759
0.0HisMet: 0.0 ± 0.0
0.533HisAsn: 0.533 ± 0.439
1.6HisPro: 1.6 ± 0.816
0.0HisGln: 0.0 ± 0.0
2.133HisArg: 2.133 ± 0.815
1.6HisSer: 1.6 ± 0.762
3.2HisThr: 3.2 ± 1.365
2.133HisVal: 2.133 ± 0.651
1.067HisTrp: 1.067 ± 0.46
0.533HisTyr: 0.533 ± 0.439
0.0HisXaa: 0.0 ± 0.0
Ile
2.133IleAla: 2.133 ± 1.149
1.6IleCys: 1.6 ± 1.466
1.067IleAsp: 1.067 ± 0.878
4.267IleGlu: 4.267 ± 2.437
2.667IlePhe: 2.667 ± 1.395
3.2IleGly: 3.2 ± 1.844
0.0IleHis: 0.0 ± 0.0
2.667IleIle: 2.667 ± 3.026
2.667IleLys: 2.667 ± 1.623
3.733IleLeu: 3.733 ± 1.074
0.533IleMet: 0.533 ± 0.442
0.533IleAsn: 0.533 ± 0.439
2.133IlePro: 2.133 ± 0.815
2.667IleGln: 2.667 ± 1.567
2.667IleArg: 2.667 ± 2.009
2.133IleSer: 2.133 ± 1.332
2.133IleThr: 2.133 ± 1.756
0.0IleVal: 0.0 ± 0.0
0.533IleTrp: 0.533 ± 0.742
1.6IleTyr: 1.6 ± 1.223
0.0IleXaa: 0.0 ± 0.0
Lys
1.6LysAla: 1.6 ± 0.815
2.667LysCys: 2.667 ± 0.839
1.067LysAsp: 1.067 ± 0.452
4.267LysGlu: 4.267 ± 0.864
3.2LysPhe: 3.2 ± 1.509
3.2LysGly: 3.2 ± 0.723
1.067LysHis: 1.067 ± 1.061
1.6LysIle: 1.6 ± 0.762
3.733LysLys: 3.733 ± 0.773
2.133LysLeu: 2.133 ± 1.558
1.067LysMet: 1.067 ± 0.45
2.133LysAsn: 2.133 ± 0.92
1.067LysPro: 1.067 ± 0.452
2.133LysGln: 2.133 ± 0.903
4.8LysArg: 4.8 ± 1.529
3.733LysSer: 3.733 ± 1.283
2.667LysThr: 2.667 ± 0.648
2.667LysVal: 2.667 ± 1.098
0.533LysTrp: 0.533 ± 0.418
2.667LysTyr: 2.667 ± 0.964
0.0LysXaa: 0.0 ± 0.0
Leu
5.867LeuAla: 5.867 ± 1.274
2.667LeuCys: 2.667 ± 1.394
3.733LeuAsp: 3.733 ± 0.772
3.733LeuGlu: 3.733 ± 2.009
3.733LeuPhe: 3.733 ± 1.573
5.333LeuGly: 5.333 ± 1.982
2.667LeuHis: 2.667 ± 0.562
3.2LeuIle: 3.2 ± 1.361
3.2LeuLys: 3.2 ± 0.907
9.067LeuLeu: 9.067 ± 4.726
1.067LeuMet: 1.067 ± 0.46
2.667LeuAsn: 2.667 ± 1.623
4.267LeuPro: 4.267 ± 1.986
7.467LeuGln: 7.467 ± 1.87
4.267LeuArg: 4.267 ± 1.833
5.867LeuSer: 5.867 ± 1.816
4.8LeuThr: 4.8 ± 2.878
2.667LeuVal: 2.667 ± 1.214
0.533LeuTrp: 0.533 ± 0.474
4.267LeuTyr: 4.267 ± 0.99
0.0LeuXaa: 0.0 ± 0.0
Met
0.533MetAla: 0.533 ± 0.474
1.067MetCys: 1.067 ± 0.837
1.6MetAsp: 1.6 ± 0.815
1.6MetGlu: 1.6 ± 0.666
1.6MetPhe: 1.6 ± 0.754
1.067MetGly: 1.067 ± 0.948
0.533MetHis: 0.533 ± 0.418
0.533MetIle: 0.533 ± 1.052
0.533MetLys: 0.533 ± 0.439
1.067MetLeu: 1.067 ± 0.46
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
2.667MetGln: 2.667 ± 1.224
1.067MetArg: 1.067 ± 0.46
2.667MetSer: 2.667 ± 1.567
1.067MetThr: 1.067 ± 0.52
1.6MetVal: 1.6 ± 1.317
0.533MetTrp: 0.533 ± 0.418
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.733AsnAla: 3.733 ± 1.669
1.067AsnCys: 1.067 ± 0.46
2.667AsnAsp: 2.667 ± 1.083
1.6AsnGlu: 1.6 ± 0.796
0.533AsnPhe: 0.533 ± 0.742
3.733AsnGly: 3.733 ± 1.049
0.0AsnHis: 0.0 ± 0.0
1.067AsnIle: 1.067 ± 0.52
0.533AsnLys: 0.533 ± 0.418
2.133AsnLeu: 2.133 ± 1.332
1.067AsnMet: 1.067 ± 0.452
3.2AsnAsn: 3.2 ± 0.993
4.267AsnPro: 4.267 ± 1.398
2.133AsnGln: 2.133 ± 1.254
5.333AsnArg: 5.333 ± 2.862
4.267AsnSer: 4.267 ± 1.657
1.067AsnThr: 1.067 ± 0.452
1.6AsnVal: 1.6 ± 1.163
1.6AsnTrp: 1.6 ± 0.306
0.533AsnTyr: 0.533 ± 0.474
0.0AsnXaa: 0.0 ± 0.0
Pro
4.267ProAla: 4.267 ± 2.247
1.6ProCys: 1.6 ± 0.666
4.8ProAsp: 4.8 ± 1.033
4.267ProGlu: 4.267 ± 0.754
0.533ProPhe: 0.533 ± 0.439
2.667ProGly: 2.667 ± 1.539
0.0ProHis: 0.0 ± 0.0
3.2ProIle: 3.2 ± 0.788
3.2ProLys: 3.2 ± 1.291
4.8ProLeu: 4.8 ± 1.626
1.067ProMet: 1.067 ± 0.851
5.867ProAsn: 5.867 ± 1.213
8.0ProPro: 8.0 ± 2.882
0.533ProGln: 0.533 ± 0.439
5.333ProArg: 5.333 ± 2.74
8.0ProSer: 8.0 ± 3.444
2.667ProThr: 2.667 ± 1.584
2.667ProVal: 2.667 ± 1.395
0.533ProTrp: 0.533 ± 0.418
2.133ProTyr: 2.133 ± 1.345
0.0ProXaa: 0.0 ± 0.0
Gln
4.267GlnAla: 4.267 ± 1.487
0.533GlnCys: 0.533 ± 0.418
1.067GlnAsp: 1.067 ± 0.757
4.267GlnGlu: 4.267 ± 1.337
1.067GlnPhe: 1.067 ± 0.52
2.667GlnGly: 2.667 ± 0.648
2.667GlnHis: 2.667 ± 0.607
1.6GlnIle: 1.6 ± 1.237
0.533GlnLys: 0.533 ± 0.474
2.133GlnLeu: 2.133 ± 0.651
0.533GlnMet: 0.533 ± 0.474
2.667GlnAsn: 2.667 ± 1.229
1.6GlnPro: 1.6 ± 0.754
1.067GlnGln: 1.067 ± 0.52
2.667GlnArg: 2.667 ± 0.648
4.267GlnSer: 4.267 ± 1.62
3.733GlnThr: 3.733 ± 0.823
2.133GlnVal: 2.133 ± 1.188
1.6GlnTrp: 1.6 ± 0.796
3.733GlnTyr: 3.733 ± 1.415
0.0GlnXaa: 0.0 ± 0.0
Arg
6.933ArgAla: 6.933 ± 1.16
2.133ArgCys: 2.133 ± 2.126
1.6ArgAsp: 1.6 ± 0.762
3.733ArgGlu: 3.733 ± 0.732
2.667ArgPhe: 2.667 ± 0.731
8.0ArgGly: 8.0 ± 1.564
3.2ArgHis: 3.2 ± 0.611
3.2ArgIle: 3.2 ± 1.598
4.267ArgLys: 4.267 ± 0.906
7.467ArgLeu: 7.467 ± 2.082
0.533ArgMet: 0.533 ± 0.474
2.133ArgAsn: 2.133 ± 0.92
4.267ArgPro: 4.267 ± 1.763
3.2ArgGln: 3.2 ± 0.905
4.267ArgArg: 4.267 ± 0.589
4.267ArgSer: 4.267 ± 0.495
4.8ArgThr: 4.8 ± 1.828
5.867ArgVal: 5.867 ± 1.636
1.6ArgTrp: 1.6 ± 0.666
3.2ArgTyr: 3.2 ± 0.993
0.0ArgXaa: 0.0 ± 0.0
Ser
5.333SerAla: 5.333 ± 1.52
1.6SerCys: 1.6 ± 0.732
4.267SerAsp: 4.267 ± 1.649
2.667SerGlu: 2.667 ± 0.562
2.667SerPhe: 2.667 ± 1.155
4.267SerGly: 4.267 ± 0.864
1.6SerHis: 1.6 ± 0.796
3.2SerIle: 3.2 ± 1.934
4.8SerLys: 4.8 ± 1.104
8.533SerLeu: 8.533 ± 1.68
3.2SerMet: 3.2 ± 1.592
2.667SerAsn: 2.667 ± 1.345
5.867SerPro: 5.867 ± 1.9
2.667SerGln: 2.667 ± 1.368
5.867SerArg: 5.867 ± 1.463
4.8SerSer: 4.8 ± 1.977
4.8SerThr: 4.8 ± 1.797
4.8SerVal: 4.8 ± 1.229
0.0SerTrp: 0.0 ± 0.0
0.533SerTyr: 0.533 ± 0.418
0.0SerXaa: 0.0 ± 0.0
Thr
2.667ThrAla: 2.667 ± 1.224
0.533ThrCys: 0.533 ± 0.439
4.8ThrAsp: 4.8 ± 1.095
3.2ThrGlu: 3.2 ± 1.256
2.133ThrPhe: 2.133 ± 0.834
5.867ThrGly: 5.867 ± 1.814
1.067ThrHis: 1.067 ± 0.948
2.133ThrIle: 2.133 ± 0.834
3.2ThrLys: 3.2 ± 1.56
4.267ThrLeu: 4.267 ± 1.24
1.067ThrMet: 1.067 ± 0.452
2.667ThrAsn: 2.667 ± 0.839
6.933ThrPro: 6.933 ± 2.667
4.8ThrGln: 4.8 ± 0.779
3.2ThrArg: 3.2 ± 0.998
4.267ThrSer: 4.267 ± 1.483
4.267ThrThr: 4.267 ± 1.154
6.4ThrVal: 6.4 ± 1.208
1.6ThrTrp: 1.6 ± 0.762
1.067ThrTyr: 1.067 ± 0.452
0.0ThrXaa: 0.0 ± 0.0
Val
2.667ValAla: 2.667 ± 0.961
3.2ValCys: 3.2 ± 1.34
3.733ValAsp: 3.733 ± 1.061
3.2ValGlu: 3.2 ± 1.56
2.133ValPhe: 2.133 ± 1.059
4.267ValGly: 4.267 ± 0.993
1.6ValHis: 1.6 ± 0.762
1.067ValIle: 1.067 ± 0.757
4.8ValLys: 4.8 ± 1.223
6.4ValLeu: 6.4 ± 1.867
2.133ValMet: 2.133 ± 0.466
1.6ValAsn: 1.6 ± 0.306
5.867ValPro: 5.867 ± 2.519
2.133ValGln: 2.133 ± 0.55
4.8ValArg: 4.8 ± 1.138
3.733ValSer: 3.733 ± 0.648
3.733ValThr: 3.733 ± 0.772
4.267ValVal: 4.267 ± 1.306
0.0ValTrp: 0.0 ± 0.0
0.533ValTyr: 0.533 ± 0.439
0.0ValXaa: 0.0 ± 0.0
Trp
1.6TrpAla: 1.6 ± 0.306
0.0TrpCys: 0.0 ± 0.0
1.6TrpAsp: 1.6 ± 0.306
0.0TrpGlu: 0.0 ± 0.0
0.533TrpPhe: 0.533 ± 0.439
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.067TrpIle: 1.067 ± 0.878
1.6TrpLys: 1.6 ± 0.796
2.133TrpLeu: 2.133 ± 0.651
0.533TrpMet: 0.533 ± 0.439
1.067TrpAsn: 1.067 ± 0.948
0.0TrpPro: 0.0 ± 0.0
1.6TrpGln: 1.6 ± 1.255
1.6TrpArg: 1.6 ± 1.433
0.533TrpSer: 0.533 ± 0.439
1.067TrpThr: 1.067 ± 0.52
1.067TrpVal: 1.067 ± 0.46
0.0TrpTrp: 0.0 ± 0.0
0.533TrpTyr: 0.533 ± 0.439
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.667TyrAla: 2.667 ± 0.648
1.067TyrCys: 1.067 ± 1.061
0.533TyrAsp: 0.533 ± 0.439
2.133TyrGlu: 2.133 ± 0.651
0.533TyrPhe: 0.533 ± 0.439
1.067TyrGly: 1.067 ± 0.452
0.0TyrHis: 0.0 ± 0.0
1.067TyrIle: 1.067 ± 0.878
1.6TyrLys: 1.6 ± 0.815
4.8TyrLeu: 4.8 ± 1.287
0.0TyrMet: 0.0 ± 0.0
1.067TyrAsn: 1.067 ± 0.52
1.067TyrPro: 1.067 ± 0.948
0.0TyrGln: 0.0 ± 0.0
4.267TyrArg: 4.267 ± 0.686
2.667TyrSer: 2.667 ± 0.748
2.133TyrThr: 2.133 ± 1.188
1.6TyrVal: 1.6 ± 0.796
2.667TyrTrp: 2.667 ± 1.229
1.6TyrTyr: 1.6 ± 0.903
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1876 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski