Amino acid dipepetide frequency for Mint virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.221AlaAla: 5.221 ± 0.558
1.004AlaCys: 1.004 ± 0.349
3.012AlaAsp: 3.012 ± 1.003
3.213AlaGlu: 3.213 ± 0.619
3.012AlaPhe: 3.012 ± 0.663
2.61AlaGly: 2.61 ± 0.701
0.602AlaHis: 0.602 ± 0.279
4.418AlaIle: 4.418 ± 0.805
2.61AlaLys: 2.61 ± 0.976
6.024AlaLeu: 6.024 ± 1.485
0.602AlaMet: 0.602 ± 0.266
1.807AlaAsn: 1.807 ± 0.372
2.811AlaPro: 2.811 ± 0.885
1.807AlaGln: 1.807 ± 0.572
4.217AlaArg: 4.217 ± 1.023
4.819AlaSer: 4.819 ± 0.784
2.811AlaThr: 2.811 ± 0.665
4.618AlaVal: 4.618 ± 1.071
0.0AlaTrp: 0.0 ± 0.0
1.606AlaTyr: 1.606 ± 0.418
0.0AlaXaa: 0.0 ± 0.0
Cys
1.205CysAla: 1.205 ± 0.724
0.602CysCys: 0.602 ± 0.233
2.41CysAsp: 2.41 ± 0.376
0.803CysGlu: 0.803 ± 0.323
1.807CysPhe: 1.807 ± 0.415
3.012CysGly: 3.012 ± 0.573
0.402CysHis: 0.402 ± 0.238
1.004CysIle: 1.004 ± 0.491
1.606CysLys: 1.606 ± 0.718
2.61CysLeu: 2.61 ± 0.756
0.0CysMet: 0.0 ± 0.0
0.402CysAsn: 0.402 ± 0.216
0.602CysPro: 0.602 ± 0.356
0.201CysGln: 0.201 ± 0.119
1.807CysArg: 1.807 ± 0.729
3.614CysSer: 3.614 ± 0.598
1.406CysThr: 1.406 ± 0.353
0.602CysVal: 0.602 ± 0.232
0.201CysTrp: 0.201 ± 0.259
1.004CysTyr: 1.004 ± 0.393
0.0CysXaa: 0.0 ± 0.0
Asp
3.414AspAla: 3.414 ± 0.908
1.807AspCys: 1.807 ± 0.432
2.811AspAsp: 2.811 ± 0.86
4.418AspGlu: 4.418 ± 0.637
4.618AspPhe: 4.618 ± 1.144
3.012AspGly: 3.012 ± 0.948
0.602AspHis: 0.602 ± 0.279
5.02AspIle: 5.02 ± 1.064
2.008AspLys: 2.008 ± 0.917
6.024AspLeu: 6.024 ± 1.202
1.807AspMet: 1.807 ± 0.928
1.205AspAsn: 1.205 ± 0.438
1.807AspPro: 1.807 ± 0.425
0.402AspGln: 0.402 ± 0.25
3.614AspArg: 3.614 ± 0.747
7.631AspSer: 7.631 ± 0.976
2.008AspThr: 2.008 ± 0.828
5.622AspVal: 5.622 ± 0.839
0.0AspTrp: 0.0 ± 0.0
2.008AspTyr: 2.008 ± 0.853
0.0AspXaa: 0.0 ± 0.0
Glu
2.41GluAla: 2.41 ± 0.709
1.606GluCys: 1.606 ± 0.764
1.807GluAsp: 1.807 ± 0.62
2.811GluGlu: 2.811 ± 0.421
3.414GluPhe: 3.414 ± 0.684
2.008GluGly: 2.008 ± 0.512
1.004GluHis: 1.004 ± 0.484
3.614GluIle: 3.614 ± 1.184
4.819GluLys: 4.819 ± 0.679
5.422GluLeu: 5.422 ± 0.835
1.406GluMet: 1.406 ± 0.388
3.012GluAsn: 3.012 ± 0.667
1.406GluPro: 1.406 ± 0.649
1.807GluGln: 1.807 ± 0.597
5.02GluArg: 5.02 ± 0.716
4.618GluSer: 4.618 ± 1.147
3.012GluThr: 3.012 ± 0.719
4.618GluVal: 4.618 ± 0.891
0.602GluTrp: 0.602 ± 0.279
2.811GluTyr: 2.811 ± 0.36
0.0GluXaa: 0.0 ± 0.0
Phe
2.41PheAla: 2.41 ± 0.834
1.606PheCys: 1.606 ± 0.434
4.418PheAsp: 4.418 ± 1.21
4.819PheGlu: 4.819 ± 0.813
3.012PhePhe: 3.012 ± 0.678
3.213PheGly: 3.213 ± 0.547
2.209PheHis: 2.209 ± 0.413
3.414PheIle: 3.414 ± 0.626
3.614PheLys: 3.614 ± 1.129
4.016PheLeu: 4.016 ± 0.681
1.004PheMet: 1.004 ± 0.372
1.406PheAsn: 1.406 ± 0.429
1.606PhePro: 1.606 ± 0.484
0.602PheGln: 0.602 ± 0.356
3.213PheArg: 3.213 ± 0.92
9.036PheSer: 9.036 ± 1.651
3.815PheThr: 3.815 ± 0.667
7.028PheVal: 7.028 ± 1.414
0.0PheTrp: 0.0 ± 0.0
1.606PheTyr: 1.606 ± 0.408
0.0PheXaa: 0.0 ± 0.0
Gly
2.811GlyAla: 2.811 ± 0.959
1.205GlyCys: 1.205 ± 0.52
3.614GlyAsp: 3.614 ± 1.03
4.217GlyGlu: 4.217 ± 0.709
2.41GlyPhe: 2.41 ± 0.502
6.225GlyGly: 6.225 ± 1.509
1.606GlyHis: 1.606 ± 0.612
1.807GlyIle: 1.807 ± 0.682
4.618GlyLys: 4.618 ± 0.728
4.016GlyLeu: 4.016 ± 0.267
0.602GlyMet: 0.602 ± 0.325
2.008GlyAsn: 2.008 ± 0.761
0.402GlyPro: 0.402 ± 0.238
0.402GlyGln: 0.402 ± 0.238
2.61GlyArg: 2.61 ± 0.642
3.414GlySer: 3.414 ± 0.767
3.012GlyThr: 3.012 ± 0.71
3.815GlyVal: 3.815 ± 0.797
0.602GlyTrp: 0.602 ± 0.524
2.008GlyTyr: 2.008 ± 0.532
0.0GlyXaa: 0.0 ± 0.0
His
2.209HisAla: 2.209 ± 0.781
1.807HisCys: 1.807 ± 0.694
1.606HisAsp: 1.606 ± 0.602
0.803HisGlu: 0.803 ± 0.233
0.803HisPhe: 0.803 ± 0.553
0.201HisGly: 0.201 ± 0.351
0.602HisHis: 0.602 ± 0.356
1.205HisIle: 1.205 ± 0.332
1.004HisLys: 1.004 ± 0.238
0.803HisLeu: 0.803 ± 0.393
0.201HisMet: 0.201 ± 0.265
0.402HisAsn: 0.402 ± 0.181
0.602HisPro: 0.602 ± 0.233
0.402HisGln: 0.402 ± 0.226
1.606HisArg: 1.606 ± 0.95
2.41HisSer: 2.41 ± 0.637
0.803HisThr: 0.803 ± 0.475
2.209HisVal: 2.209 ± 0.619
0.402HisTrp: 0.402 ± 0.216
1.406HisTyr: 1.406 ± 0.443
0.0HisXaa: 0.0 ± 0.0
Ile
1.406IleAla: 1.406 ± 0.383
1.004IleCys: 1.004 ± 0.444
4.418IleAsp: 4.418 ± 0.982
3.213IleGlu: 3.213 ± 0.49
2.61IlePhe: 2.61 ± 0.578
1.606IleGly: 1.606 ± 0.439
2.008IleHis: 2.008 ± 0.626
3.815IleIle: 3.815 ± 0.868
3.414IleLys: 3.414 ± 1.303
2.811IleLeu: 2.811 ± 0.57
1.004IleMet: 1.004 ± 0.471
3.614IleAsn: 3.614 ± 0.858
2.811IlePro: 2.811 ± 0.553
0.402IleGln: 0.402 ± 0.238
3.012IleArg: 3.012 ± 0.534
7.229IleSer: 7.229 ± 1.421
2.61IleThr: 2.61 ± 0.503
6.024IleVal: 6.024 ± 1.001
0.0IleTrp: 0.0 ± 0.0
1.406IleTyr: 1.406 ± 0.37
0.0IleXaa: 0.0 ± 0.0
Lys
3.213LysAla: 3.213 ± 1.09
1.205LysCys: 1.205 ± 0.543
3.012LysAsp: 3.012 ± 1.093
2.61LysGlu: 2.61 ± 0.757
4.618LysPhe: 4.618 ± 0.769
3.213LysGly: 3.213 ± 0.63
1.406LysHis: 1.406 ± 0.377
2.41LysIle: 2.41 ± 0.596
2.209LysLys: 2.209 ± 0.594
6.426LysLeu: 6.426 ± 1.839
0.602LysMet: 0.602 ± 0.233
3.414LysAsn: 3.414 ± 0.547
1.807LysPro: 1.807 ± 0.701
1.606LysGln: 1.606 ± 0.575
4.418LysArg: 4.418 ± 0.502
4.618LysSer: 4.618 ± 0.566
2.811LysThr: 2.811 ± 0.772
4.418LysVal: 4.418 ± 0.93
0.803LysTrp: 0.803 ± 0.665
2.008LysTyr: 2.008 ± 0.642
0.0LysXaa: 0.0 ± 0.0
Leu
5.622LeuAla: 5.622 ± 1.099
1.205LeuCys: 1.205 ± 0.334
5.221LeuAsp: 5.221 ± 0.82
3.815LeuGlu: 3.815 ± 0.536
6.024LeuPhe: 6.024 ± 1.018
5.221LeuGly: 5.221 ± 1.555
2.008LeuHis: 2.008 ± 0.763
4.016LeuIle: 4.016 ± 0.878
3.815LeuLys: 3.815 ± 0.85
7.43LeuLeu: 7.43 ± 1.289
2.209LeuMet: 2.209 ± 1.082
5.823LeuAsn: 5.823 ± 1.767
4.016LeuPro: 4.016 ± 1.014
2.008LeuGln: 2.008 ± 1.326
5.422LeuArg: 5.422 ± 1.509
10.843LeuSer: 10.843 ± 1.473
5.221LeuThr: 5.221 ± 1.438
6.024LeuVal: 6.024 ± 0.689
0.402LeuTrp: 0.402 ± 0.372
2.61LeuTyr: 2.61 ± 0.639
0.0LeuXaa: 0.0 ± 0.0
Met
0.803MetAla: 0.803 ± 0.342
1.004MetCys: 1.004 ± 0.352
1.205MetAsp: 1.205 ± 0.336
1.004MetGlu: 1.004 ± 0.262
1.004MetPhe: 1.004 ± 0.323
0.803MetGly: 0.803 ± 0.316
0.201MetHis: 0.201 ± 0.2
1.004MetIle: 1.004 ± 0.393
1.406MetLys: 1.406 ± 0.523
1.807MetLeu: 1.807 ± 0.527
0.602MetMet: 0.602 ± 0.315
1.004MetAsn: 1.004 ± 0.365
0.402MetPro: 0.402 ± 0.216
0.402MetGln: 0.402 ± 0.216
0.402MetArg: 0.402 ± 0.216
2.008MetSer: 2.008 ± 0.32
0.602MetThr: 0.602 ± 0.232
2.41MetVal: 2.41 ± 0.468
0.0MetTrp: 0.0 ± 0.0
1.205MetTyr: 1.205 ± 0.476
0.0MetXaa: 0.0 ± 0.0
Asn
2.61AsnAla: 2.61 ± 0.633
0.602AsnCys: 0.602 ± 0.362
2.008AsnAsp: 2.008 ± 0.772
3.614AsnGlu: 3.614 ± 0.586
3.815AsnPhe: 3.815 ± 0.816
2.008AsnGly: 2.008 ± 0.761
1.606AsnHis: 1.606 ± 0.404
1.807AsnIle: 1.807 ± 0.88
1.807AsnLys: 1.807 ± 0.618
4.819AsnLeu: 4.819 ± 0.599
0.201AsnMet: 0.201 ± 0.276
1.205AsnAsn: 1.205 ± 0.553
0.402AsnPro: 0.402 ± 0.374
0.602AsnGln: 0.602 ± 0.238
4.217AsnArg: 4.217 ± 0.825
5.823AsnSer: 5.823 ± 1.038
2.811AsnThr: 2.811 ± 0.519
2.61AsnVal: 2.61 ± 0.916
0.0AsnTrp: 0.0 ± 0.0
1.004AsnTyr: 1.004 ± 0.371
0.0AsnXaa: 0.0 ± 0.0
Pro
2.008ProAla: 2.008 ± 0.45
0.602ProCys: 0.602 ± 0.238
1.807ProAsp: 1.807 ± 0.685
1.606ProGlu: 1.606 ± 0.764
3.614ProPhe: 3.614 ± 0.712
2.41ProGly: 2.41 ± 0.67
0.602ProHis: 0.602 ± 0.315
2.41ProIle: 2.41 ± 1.136
1.606ProLys: 1.606 ± 0.477
4.016ProLeu: 4.016 ± 1.007
1.205ProMet: 1.205 ± 0.356
1.406ProAsn: 1.406 ± 0.348
1.004ProPro: 1.004 ± 0.673
1.004ProGln: 1.004 ± 0.394
1.807ProArg: 1.807 ± 0.686
3.815ProSer: 3.815 ± 0.793
2.41ProThr: 2.41 ± 0.887
2.61ProVal: 2.61 ± 1.096
0.201ProTrp: 0.201 ± 0.119
1.004ProTyr: 1.004 ± 0.363
0.0ProXaa: 0.0 ± 0.0
Gln
1.205GlnAla: 1.205 ± 1.091
0.402GlnCys: 0.402 ± 0.37
1.004GlnAsp: 1.004 ± 0.372
0.602GlnGlu: 0.602 ± 0.238
1.004GlnPhe: 1.004 ± 0.393
0.803GlnGly: 0.803 ± 0.344
0.201GlnHis: 0.201 ± 0.259
1.205GlnIle: 1.205 ± 0.327
1.606GlnLys: 1.606 ± 0.702
2.209GlnLeu: 2.209 ± 0.766
0.0GlnMet: 0.0 ± 0.0
1.004GlnAsn: 1.004 ± 0.491
1.406GlnPro: 1.406 ± 0.383
0.402GlnGln: 0.402 ± 0.238
2.008GlnArg: 2.008 ± 0.628
1.606GlnSer: 1.606 ± 0.479
0.803GlnThr: 0.803 ± 0.393
1.406GlnVal: 1.406 ± 0.524
0.0GlnTrp: 0.0 ± 0.0
0.402GlnTyr: 0.402 ± 0.222
0.0GlnXaa: 0.0 ± 0.0
Arg
4.618ArgAla: 4.618 ± 1.271
2.209ArgCys: 2.209 ± 0.865
4.819ArgAsp: 4.819 ± 0.746
2.811ArgGlu: 2.811 ± 0.505
3.213ArgPhe: 3.213 ± 0.53
2.811ArgGly: 2.811 ± 0.904
0.803ArgHis: 0.803 ± 0.3
2.61ArgIle: 2.61 ± 0.733
3.815ArgLys: 3.815 ± 1.177
5.02ArgLeu: 5.02 ± 0.972
1.606ArgMet: 1.606 ± 0.531
4.217ArgAsn: 4.217 ± 1.212
1.807ArgPro: 1.807 ± 0.257
2.41ArgGln: 2.41 ± 0.791
6.426ArgArg: 6.426 ± 1.244
6.024ArgSer: 6.024 ± 0.917
3.414ArgThr: 3.414 ± 0.709
5.221ArgVal: 5.221 ± 0.94
0.201ArgTrp: 0.201 ± 0.2
1.406ArgTyr: 1.406 ± 0.308
0.0ArgXaa: 0.0 ± 0.0
Ser
6.426SerAla: 6.426 ± 1.041
3.414SerCys: 3.414 ± 0.608
6.024SerAsp: 6.024 ± 0.692
6.827SerGlu: 6.827 ± 0.708
7.229SerPhe: 7.229 ± 0.858
4.016SerGly: 4.016 ± 0.772
1.606SerHis: 1.606 ± 0.376
6.024SerIle: 6.024 ± 1.122
6.024SerLys: 6.024 ± 0.969
9.639SerLeu: 9.639 ± 2.121
2.209SerMet: 2.209 ± 0.321
3.815SerAsn: 3.815 ± 0.519
3.815SerPro: 3.815 ± 1.089
2.41SerGln: 2.41 ± 0.705
6.225SerArg: 6.225 ± 0.513
9.036SerSer: 9.036 ± 2.017
5.622SerThr: 5.622 ± 1.799
9.839SerVal: 9.839 ± 1.11
0.402SerTrp: 0.402 ± 0.372
3.012SerTyr: 3.012 ± 0.826
0.0SerXaa: 0.0 ± 0.0
Thr
2.811ThrAla: 2.811 ± 0.878
1.807ThrCys: 1.807 ± 0.372
2.811ThrAsp: 2.811 ± 1.117
2.811ThrGlu: 2.811 ± 0.54
3.414ThrPhe: 3.414 ± 0.68
2.41ThrGly: 2.41 ± 1.164
1.406ThrHis: 1.406 ± 0.704
2.008ThrIle: 2.008 ± 0.569
2.41ThrLys: 2.41 ± 0.781
4.618ThrLeu: 4.618 ± 1.398
1.606ThrMet: 1.606 ± 0.764
2.41ThrAsn: 2.41 ± 0.646
3.815ThrPro: 3.815 ± 0.64
0.803ThrGln: 0.803 ± 0.232
2.008ThrArg: 2.008 ± 0.568
6.225ThrSer: 6.225 ± 0.49
3.012ThrThr: 3.012 ± 0.632
4.418ThrVal: 4.418 ± 1.187
0.803ThrTrp: 0.803 ± 0.236
1.606ThrTyr: 1.606 ± 0.931
0.0ThrXaa: 0.0 ± 0.0
Val
4.618ValAla: 4.618 ± 1.32
1.606ValCys: 1.606 ± 0.412
4.217ValAsp: 4.217 ± 0.505
5.823ValGlu: 5.823 ± 1.083
4.016ValPhe: 4.016 ± 0.686
3.815ValGly: 3.815 ± 0.865
1.606ValHis: 1.606 ± 0.611
4.217ValIle: 4.217 ± 0.774
6.426ValLys: 6.426 ± 1.026
5.221ValLeu: 5.221 ± 1.248
1.004ValMet: 1.004 ± 0.455
4.217ValAsn: 4.217 ± 0.895
6.024ValPro: 6.024 ± 1.405
1.205ValGln: 1.205 ± 0.444
5.823ValArg: 5.823 ± 1.423
8.233ValSer: 8.233 ± 0.934
4.217ValThr: 4.217 ± 0.924
9.036ValVal: 9.036 ± 1.493
0.201ValTrp: 0.201 ± 0.119
3.614ValTyr: 3.614 ± 1.164
0.0ValXaa: 0.0 ± 0.0
Trp
0.402TrpAla: 0.402 ± 0.518
0.201TrpCys: 0.201 ± 0.259
0.201TrpAsp: 0.201 ± 0.119
0.201TrpGlu: 0.201 ± 0.259
0.201TrpPhe: 0.201 ± 0.119
0.0TrpGly: 0.0 ± 0.0
0.201TrpHis: 0.201 ± 0.259
0.803TrpIle: 0.803 ± 0.608
0.201TrpLys: 0.201 ± 0.119
0.402TrpLeu: 0.402 ± 0.222
0.402TrpMet: 0.402 ± 0.445
0.402TrpAsn: 0.402 ± 0.216
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.402TrpSer: 0.402 ± 0.228
0.402TrpThr: 0.402 ± 0.25
0.201TrpVal: 0.201 ± 0.264
0.0TrpTrp: 0.0 ± 0.0
0.201TrpTyr: 0.201 ± 0.248
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.406TyrAla: 1.406 ± 0.523
0.402TyrCys: 0.402 ± 0.216
3.414TyrAsp: 3.414 ± 1.034
1.205TyrGlu: 1.205 ± 0.426
2.209TyrPhe: 2.209 ± 1.39
2.008TyrGly: 2.008 ± 1.072
0.803TyrHis: 0.803 ± 0.361
1.606TyrIle: 1.606 ± 0.428
1.807TyrLys: 1.807 ± 0.585
5.622TyrLeu: 5.622 ± 1.011
0.803TyrMet: 0.803 ± 0.3
0.803TyrAsn: 0.803 ± 0.34
0.602TyrPro: 0.602 ± 0.356
0.402TyrGln: 0.402 ± 0.181
1.606TyrArg: 1.606 ± 0.416
2.209TyrSer: 2.209 ± 1.095
2.41TyrThr: 2.41 ± 0.847
2.61TyrVal: 2.61 ± 1.101
0.0TyrTrp: 0.0 ± 0.0
2.209TyrTyr: 2.209 ± 0.539
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (4981 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski