Amino acid dipepetide frequency for Sulfolobales Mexican rudivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.382AlaCys: 0.382 ± 0.216
3.566AlaAsp: 3.566 ± 0.869
3.312AlaGlu: 3.312 ± 0.908
3.566AlaPhe: 3.566 ± 0.654
3.057AlaGly: 3.057 ± 0.624
0.764AlaHis: 0.764 ± 0.304
5.986AlaIle: 5.986 ± 0.88
4.076AlaLys: 4.076 ± 0.667
10.317AlaLeu: 10.317 ± 1.354
2.802AlaMet: 2.802 ± 0.657
4.076AlaAsn: 4.076 ± 0.68
2.547AlaPro: 2.547 ± 0.573
3.312AlaGln: 3.312 ± 0.885
3.694AlaArg: 3.694 ± 0.777
4.84AlaSer: 4.84 ± 0.767
3.439AlaThr: 3.439 ± 0.727
6.496AlaVal: 6.496 ± 0.798
1.019AlaTrp: 1.019 ± 0.33
4.968AlaTyr: 4.968 ± 0.793
0.0AlaXaa: 0.0 ± 0.0
Cys
0.382CysAla: 0.382 ± 0.243
0.0CysCys: 0.0 ± 0.0
0.637CysAsp: 0.637 ± 0.329
0.637CysGlu: 0.637 ± 0.313
0.127CysPhe: 0.127 ± 0.152
0.637CysGly: 0.637 ± 0.384
0.127CysHis: 0.127 ± 0.128
0.255CysIle: 0.255 ± 0.172
0.382CysLys: 0.382 ± 0.221
0.637CysLeu: 0.637 ± 0.275
0.0CysMet: 0.0 ± 0.0
0.255CysAsn: 0.255 ± 0.185
0.255CysPro: 0.255 ± 0.2
0.764CysGln: 0.764 ± 0.327
0.127CysArg: 0.127 ± 0.16
0.764CysSer: 0.764 ± 0.331
0.509CysThr: 0.509 ± 0.318
0.637CysVal: 0.637 ± 0.305
0.127CysTrp: 0.127 ± 0.155
0.509CysTyr: 0.509 ± 0.254
0.0CysXaa: 0.0 ± 0.0
Asp
3.821AspAla: 3.821 ± 0.682
0.382AspCys: 0.382 ± 0.255
1.274AspAsp: 1.274 ± 0.344
3.821AspGlu: 3.821 ± 0.861
3.439AspPhe: 3.439 ± 0.657
2.293AspGly: 2.293 ± 0.673
0.892AspHis: 0.892 ± 0.335
2.675AspIle: 2.675 ± 0.502
1.656AspLys: 1.656 ± 0.58
5.859AspLeu: 5.859 ± 0.922
1.274AspMet: 1.274 ± 0.405
2.165AspAsn: 2.165 ± 0.609
1.656AspPro: 1.656 ± 0.367
2.547AspGln: 2.547 ± 0.746
1.274AspArg: 1.274 ± 0.418
1.019AspSer: 1.019 ± 0.42
1.911AspThr: 1.911 ± 0.424
4.968AspVal: 4.968 ± 0.815
0.892AspTrp: 0.892 ± 0.303
2.675AspTyr: 2.675 ± 0.523
0.0AspXaa: 0.0 ± 0.0
Glu
3.312GluAla: 3.312 ± 0.613
0.127GluCys: 0.127 ± 0.129
3.184GluAsp: 3.184 ± 0.555
5.095GluGlu: 5.095 ± 1.786
3.312GluPhe: 3.312 ± 0.664
3.057GluGly: 3.057 ± 0.612
1.401GluHis: 1.401 ± 0.413
5.859GluIle: 5.859 ± 0.959
5.732GluLys: 5.732 ± 1.084
5.604GluLeu: 5.604 ± 0.926
1.783GluMet: 1.783 ± 0.511
2.802GluAsn: 2.802 ± 0.587
1.783GluPro: 1.783 ± 0.376
1.911GluGln: 1.911 ± 0.355
2.93GluArg: 2.93 ± 1.263
2.038GluSer: 2.038 ± 0.508
2.675GluThr: 2.675 ± 0.505
4.585GluVal: 4.585 ± 0.933
0.255GluTrp: 0.255 ± 0.154
2.675GluTyr: 2.675 ± 0.587
0.0GluXaa: 0.0 ± 0.0
Phe
4.076PheAla: 4.076 ± 0.853
1.146PheCys: 1.146 ± 0.593
3.949PheAsp: 3.949 ± 0.897
2.038PheGlu: 2.038 ± 0.476
2.038PhePhe: 2.038 ± 0.584
1.401PheGly: 1.401 ± 0.455
1.019PheHis: 1.019 ± 0.331
3.694PheIle: 3.694 ± 0.547
1.783PheLys: 1.783 ± 0.751
5.222PheLeu: 5.222 ± 1.053
1.146PheMet: 1.146 ± 0.428
2.93PheAsn: 2.93 ± 0.529
1.656PhePro: 1.656 ± 0.472
2.165PheGln: 2.165 ± 0.375
1.401PheArg: 1.401 ± 0.375
2.42PheSer: 2.42 ± 0.568
2.038PheThr: 2.038 ± 0.463
3.694PheVal: 3.694 ± 0.737
0.0PheTrp: 0.0 ± 0.0
2.802PheTyr: 2.802 ± 0.615
0.0PheXaa: 0.0 ± 0.0
Gly
3.184GlyAla: 3.184 ± 0.646
0.637GlyCys: 0.637 ± 0.311
1.783GlyAsp: 1.783 ± 0.526
2.675GlyGlu: 2.675 ± 1.041
2.547GlyPhe: 2.547 ± 0.659
2.547GlyGly: 2.547 ± 0.686
0.509GlyHis: 0.509 ± 0.212
3.821GlyIle: 3.821 ± 0.709
2.165GlyLys: 2.165 ± 0.498
3.949GlyLeu: 3.949 ± 0.647
0.764GlyMet: 0.764 ± 0.315
2.93GlyAsn: 2.93 ± 0.681
1.783GlyPro: 1.783 ± 0.532
2.038GlyGln: 2.038 ± 0.457
1.911GlyArg: 1.911 ± 0.546
3.439GlySer: 3.439 ± 0.633
3.439GlyThr: 3.439 ± 0.714
5.095GlyVal: 5.095 ± 1.191
0.509GlyTrp: 0.509 ± 0.28
4.458GlyTyr: 4.458 ± 0.813
0.0GlyXaa: 0.0 ± 0.0
His
1.783HisAla: 1.783 ± 0.697
0.255HisCys: 0.255 ± 0.305
0.892HisAsp: 0.892 ± 0.376
1.019HisGlu: 1.019 ± 0.375
1.274HisPhe: 1.274 ± 0.381
1.528HisGly: 1.528 ± 0.466
0.637HisHis: 0.637 ± 0.359
1.274HisIle: 1.274 ± 0.479
0.509HisLys: 0.509 ± 0.42
0.892HisLeu: 0.892 ± 0.41
0.382HisMet: 0.382 ± 0.216
0.255HisAsn: 0.255 ± 0.176
0.382HisPro: 0.382 ± 0.208
0.509HisGln: 0.509 ± 0.202
0.382HisArg: 0.382 ± 0.238
0.509HisSer: 0.509 ± 0.316
0.509HisThr: 0.509 ± 0.288
2.165HisVal: 2.165 ± 0.759
0.127HisTrp: 0.127 ± 0.158
0.892HisTyr: 0.892 ± 0.362
0.0HisXaa: 0.0 ± 0.0
Ile
7.005IleAla: 7.005 ± 0.989
0.637IleCys: 0.637 ± 0.303
2.42IleAsp: 2.42 ± 0.682
4.84IleGlu: 4.84 ± 0.906
2.547IlePhe: 2.547 ± 0.544
1.911IleGly: 1.911 ± 0.426
1.019IleHis: 1.019 ± 0.396
4.458IleIle: 4.458 ± 0.751
3.821IleLys: 3.821 ± 0.764
4.203IleLeu: 4.203 ± 0.596
1.274IleMet: 1.274 ± 0.565
4.203IleAsn: 4.203 ± 0.644
3.694IlePro: 3.694 ± 0.826
2.675IleGln: 2.675 ± 0.554
2.038IleArg: 2.038 ± 0.5
4.585IleSer: 4.585 ± 0.98
4.585IleThr: 4.585 ± 0.641
5.859IleVal: 5.859 ± 0.78
0.382IleTrp: 0.382 ± 0.206
3.566IleTyr: 3.566 ± 0.961
0.0IleXaa: 0.0 ± 0.0
Lys
3.184LysAla: 3.184 ± 0.772
0.255LysCys: 0.255 ± 0.194
1.783LysAsp: 1.783 ± 0.825
3.566LysGlu: 3.566 ± 0.844
1.783LysPhe: 1.783 ± 0.58
1.783LysGly: 1.783 ± 0.448
0.637LysHis: 0.637 ± 0.321
3.694LysIle: 3.694 ± 0.755
4.84LysLys: 4.84 ± 1.169
6.751LysLeu: 6.751 ± 1.122
1.656LysMet: 1.656 ± 0.534
1.528LysAsn: 1.528 ± 0.436
1.401LysPro: 1.401 ± 0.343
2.038LysGln: 2.038 ± 0.54
2.293LysArg: 2.293 ± 0.62
3.566LysSer: 3.566 ± 0.702
3.184LysThr: 3.184 ± 0.592
3.439LysVal: 3.439 ± 0.721
1.019LysTrp: 1.019 ± 0.39
3.439LysTyr: 3.439 ± 0.778
0.0LysXaa: 0.0 ± 0.0
Leu
7.388LeuAla: 7.388 ± 1.012
0.255LeuCys: 0.255 ± 0.198
3.949LeuAsp: 3.949 ± 0.679
5.222LeuGlu: 5.222 ± 1.047
4.076LeuPhe: 4.076 ± 0.69
5.222LeuGly: 5.222 ± 0.752
1.401LeuHis: 1.401 ± 0.44
6.623LeuIle: 6.623 ± 1.168
5.986LeuLys: 5.986 ± 1.062
10.062LeuLeu: 10.062 ± 1.079
3.057LeuMet: 3.057 ± 0.459
4.331LeuAsn: 4.331 ± 0.704
4.968LeuPro: 4.968 ± 0.986
5.732LeuGln: 5.732 ± 0.921
5.859LeuArg: 5.859 ± 1.228
8.407LeuSer: 8.407 ± 1.084
6.241LeuThr: 6.241 ± 0.873
6.878LeuVal: 6.878 ± 1.018
0.892LeuTrp: 0.892 ± 0.248
4.968LeuTyr: 4.968 ± 1.295
0.0LeuXaa: 0.0 ± 0.0
Met
1.911MetAla: 1.911 ± 0.575
0.0MetCys: 0.0 ± 0.0
1.146MetAsp: 1.146 ± 0.46
1.146MetGlu: 1.146 ± 0.45
1.146MetPhe: 1.146 ± 0.403
0.637MetGly: 0.637 ± 0.257
0.382MetHis: 0.382 ± 0.251
1.401MetIle: 1.401 ± 0.412
1.911MetLys: 1.911 ± 0.409
2.547MetLeu: 2.547 ± 0.432
0.382MetMet: 0.382 ± 0.25
0.509MetAsn: 0.509 ± 0.26
1.401MetPro: 1.401 ± 0.419
1.019MetGln: 1.019 ± 0.336
1.019MetArg: 1.019 ± 0.353
1.783MetSer: 1.783 ± 0.371
1.911MetThr: 1.911 ± 0.633
1.783MetVal: 1.783 ± 0.493
0.255MetTrp: 0.255 ± 0.187
1.656MetTyr: 1.656 ± 0.611
0.0MetXaa: 0.0 ± 0.0
Asn
5.604AsnAla: 5.604 ± 1.098
0.509AsnCys: 0.509 ± 0.265
2.547AsnAsp: 2.547 ± 0.43
2.93AsnGlu: 2.93 ± 0.582
2.802AsnPhe: 2.802 ± 0.512
3.184AsnGly: 3.184 ± 0.897
0.382AsnHis: 0.382 ± 0.226
2.93AsnIle: 2.93 ± 0.6
1.274AsnLys: 1.274 ± 0.36
6.241AsnLeu: 6.241 ± 1.391
0.892AsnMet: 0.892 ± 0.295
3.184AsnAsn: 3.184 ± 0.762
2.675AsnPro: 2.675 ± 0.522
1.911AsnGln: 1.911 ± 0.74
1.019AsnArg: 1.019 ± 0.371
3.312AsnSer: 3.312 ± 0.824
2.802AsnThr: 2.802 ± 0.524
5.859AsnVal: 5.859 ± 0.925
0.382AsnTrp: 0.382 ± 0.227
2.802AsnTyr: 2.802 ± 0.453
0.0AsnXaa: 0.0 ± 0.0
Pro
3.821ProAla: 3.821 ± 0.613
0.382ProCys: 0.382 ± 0.197
1.656ProAsp: 1.656 ± 0.391
2.42ProGlu: 2.42 ± 0.543
1.911ProPhe: 1.911 ± 0.415
1.911ProGly: 1.911 ± 0.606
1.019ProHis: 1.019 ± 0.299
2.165ProIle: 2.165 ± 0.575
1.401ProLys: 1.401 ± 0.481
3.439ProLeu: 3.439 ± 0.581
0.892ProMet: 0.892 ± 0.407
2.165ProAsn: 2.165 ± 0.687
2.165ProPro: 2.165 ± 0.534
1.146ProGln: 1.146 ± 0.317
2.293ProArg: 2.293 ± 0.545
3.312ProSer: 3.312 ± 0.542
2.038ProThr: 2.038 ± 0.709
4.458ProVal: 4.458 ± 0.734
0.255ProTrp: 0.255 ± 0.168
1.911ProTyr: 1.911 ± 0.406
0.0ProXaa: 0.0 ± 0.0
Gln
3.694GlnAla: 3.694 ± 0.623
0.509GlnCys: 0.509 ± 0.201
1.146GlnAsp: 1.146 ± 0.404
1.274GlnGlu: 1.274 ± 0.376
2.165GlnPhe: 2.165 ± 0.713
2.038GlnGly: 2.038 ± 0.62
0.637GlnHis: 0.637 ± 0.309
3.439GlnIle: 3.439 ± 0.562
1.783GlnLys: 1.783 ± 0.452
4.458GlnLeu: 4.458 ± 1.183
0.509GlnMet: 0.509 ± 0.264
4.585GlnAsn: 4.585 ± 1.055
1.656GlnPro: 1.656 ± 0.555
2.93GlnGln: 2.93 ± 0.885
1.911GlnArg: 1.911 ± 0.512
2.038GlnSer: 2.038 ± 0.413
2.547GlnThr: 2.547 ± 0.472
3.057GlnVal: 3.057 ± 0.424
0.382GlnTrp: 0.382 ± 0.229
4.076GlnTyr: 4.076 ± 0.708
0.0GlnXaa: 0.0 ± 0.0
Arg
3.566ArgAla: 3.566 ± 0.839
0.127ArgCys: 0.127 ± 0.16
2.42ArgAsp: 2.42 ± 0.652
4.84ArgGlu: 4.84 ± 1.238
1.401ArgPhe: 1.401 ± 0.436
2.675ArgGly: 2.675 ± 0.599
0.764ArgHis: 0.764 ± 0.353
2.165ArgIle: 2.165 ± 0.537
2.675ArgLys: 2.675 ± 0.71
4.331ArgLeu: 4.331 ± 0.852
0.764ArgMet: 0.764 ± 0.282
2.293ArgAsn: 2.293 ± 0.481
1.019ArgPro: 1.019 ± 0.314
2.547ArgGln: 2.547 ± 0.597
2.165ArgArg: 2.165 ± 0.598
3.184ArgSer: 3.184 ± 0.579
2.038ArgThr: 2.038 ± 0.791
2.93ArgVal: 2.93 ± 0.673
0.255ArgTrp: 0.255 ± 0.2
2.42ArgTyr: 2.42 ± 0.595
0.0ArgXaa: 0.0 ± 0.0
Ser
5.222SerAla: 5.222 ± 0.675
0.509SerCys: 0.509 ± 0.298
2.93SerAsp: 2.93 ± 0.562
4.713SerGlu: 4.713 ± 0.642
2.675SerPhe: 2.675 ± 0.571
5.859SerGly: 5.859 ± 0.917
0.892SerHis: 0.892 ± 0.383
4.458SerIle: 4.458 ± 0.762
1.783SerLys: 1.783 ± 0.545
5.477SerLeu: 5.477 ± 0.711
2.293SerMet: 2.293 ± 0.571
2.675SerAsn: 2.675 ± 0.636
2.42SerPro: 2.42 ± 0.625
2.802SerGln: 2.802 ± 0.639
3.439SerArg: 3.439 ± 0.843
7.005SerSer: 7.005 ± 2.117
3.821SerThr: 3.821 ± 0.804
4.331SerVal: 4.331 ± 0.609
0.509SerTrp: 0.509 ± 0.23
2.038SerTyr: 2.038 ± 0.552
0.0SerXaa: 0.0 ± 0.0
Thr
2.675ThrAla: 2.675 ± 0.596
0.255ThrCys: 0.255 ± 0.176
2.42ThrAsp: 2.42 ± 0.603
2.293ThrGlu: 2.293 ± 0.603
3.694ThrPhe: 3.694 ± 0.743
3.439ThrGly: 3.439 ± 0.699
1.146ThrHis: 1.146 ± 0.443
3.312ThrIle: 3.312 ± 0.512
3.057ThrLys: 3.057 ± 0.713
7.388ThrLeu: 7.388 ± 1.107
0.892ThrMet: 0.892 ± 0.289
2.547ThrAsn: 2.547 ± 0.448
3.312ThrPro: 3.312 ± 0.496
2.038ThrGln: 2.038 ± 0.664
1.401ThrArg: 1.401 ± 0.385
2.675ThrSer: 2.675 ± 0.852
5.222ThrThr: 5.222 ± 0.83
4.713ThrVal: 4.713 ± 0.783
1.401ThrTrp: 1.401 ± 0.536
3.057ThrTyr: 3.057 ± 0.671
0.0ThrXaa: 0.0 ± 0.0
Val
5.986ValAla: 5.986 ± 0.983
1.019ValCys: 1.019 ± 0.381
5.095ValAsp: 5.095 ± 0.683
5.35ValGlu: 5.35 ± 0.771
3.566ValPhe: 3.566 ± 0.637
3.949ValGly: 3.949 ± 0.6
1.401ValHis: 1.401 ± 0.508
3.821ValIle: 3.821 ± 0.785
4.585ValLys: 4.585 ± 0.917
7.388ValLeu: 7.388 ± 1.116
1.401ValMet: 1.401 ± 0.438
5.477ValAsn: 5.477 ± 0.987
3.821ValPro: 3.821 ± 0.944
3.949ValGln: 3.949 ± 0.802
5.604ValArg: 5.604 ± 1.003
7.005ValSer: 7.005 ± 1.512
4.076ValThr: 4.076 ± 0.716
6.623ValVal: 6.623 ± 1.377
0.764ValTrp: 0.764 ± 0.375
3.949ValTyr: 3.949 ± 0.753
0.0ValXaa: 0.0 ± 0.0
Trp
0.892TrpAla: 0.892 ± 0.474
0.127TrpCys: 0.127 ± 0.118
0.127TrpAsp: 0.127 ± 0.155
0.509TrpGlu: 0.509 ± 0.284
0.382TrpPhe: 0.382 ± 0.184
0.382TrpGly: 0.382 ± 0.156
0.382TrpHis: 0.382 ± 0.245
0.637TrpIle: 0.637 ± 0.208
0.255TrpLys: 0.255 ± 0.147
1.274TrpLeu: 1.274 ± 0.442
0.0TrpMet: 0.0 ± 0.0
1.019TrpAsn: 1.019 ± 0.359
0.255TrpPro: 0.255 ± 0.228
0.509TrpGln: 0.509 ± 0.278
1.019TrpArg: 1.019 ± 0.289
1.019TrpSer: 1.019 ± 0.505
0.509TrpThr: 0.509 ± 0.325
0.637TrpVal: 0.637 ± 0.316
0.255TrpTrp: 0.255 ± 0.228
0.127TrpTyr: 0.127 ± 0.155
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.713TyrAla: 4.713 ± 1.031
0.255TyrCys: 0.255 ± 0.191
3.566TyrAsp: 3.566 ± 0.727
2.42TyrGlu: 2.42 ± 0.646
2.165TyrPhe: 2.165 ± 0.481
2.675TyrGly: 2.675 ± 0.665
0.764TyrHis: 0.764 ± 0.28
3.057TyrIle: 3.057 ± 0.595
2.165TyrLys: 2.165 ± 0.451
5.477TyrLeu: 5.477 ± 0.918
1.656TyrMet: 1.656 ± 0.473
3.312TyrAsn: 3.312 ± 0.522
1.911TyrPro: 1.911 ± 0.441
2.293TyrGln: 2.293 ± 0.56
2.802TyrArg: 2.802 ± 0.59
3.057TyrSer: 3.057 ± 0.47
3.439TyrThr: 3.439 ± 0.744
6.623TyrVal: 6.623 ± 1.217
0.637TyrTrp: 0.637 ± 0.281
3.057TyrTyr: 3.057 ± 0.707
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (7852 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski