Amino acid dipepetide frequency for Microbotryum lychnidis-dioicae (strain p1A1 Lamole / MvSl-1064) (Anther smut fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.473AlaAla: 10.473 ± 0.091	0.986AlaCys: 0.986 ± 0.017	3.998AlaAsp: 3.998 ± 0.037	5.023AlaGlu: 5.023 ± 0.043	3.259AlaPhe: 3.259 ± 0.036	6.023AlaGly: 6.023 ± 0.042	2.111AlaHis: 2.111 ± 0.022	3.988AlaIle: 3.988 ± 0.035	4.312AlaLys: 4.312 ± 0.046	8.787AlaLeu: 8.787 ± 0.054	1.969AlaMet: 1.969 ± 0.019	2.914AlaAsn: 2.914 ± 0.029	6.447AlaPro: 6.447 ± 0.062	3.861AlaGln: 3.861 ± 0.04	5.852AlaArg: 5.852 ± 0.045	10.244AlaSer: 10.244 ± 0.076	6.488AlaThr: 6.488 ± 0.05	5.331AlaVal: 5.331 ± 0.034	1.108AlaTrp: 1.108 ± 0.017	2.049AlaTyr: 2.049 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.907CysAla: 0.907 ± 0.015	0.185CysCys: 0.185 ± 0.008	0.549CysAsp: 0.549 ± 0.012	0.501CysGlu: 0.501 ± 0.013	0.442CysPhe: 0.442 ± 0.012	0.789CysGly: 0.789 ± 0.023	0.246CysHis: 0.246 ± 0.008	0.522CysIle: 0.522 ± 0.011	0.415CysLys: 0.415 ± 0.011	1.037CysLeu: 1.037 ± 0.018	0.19CysMet: 0.19 ± 0.007	0.31CysAsn: 0.31 ± 0.013	0.583CysPro: 0.583 ± 0.014	0.368CysGln: 0.368 ± 0.012	0.639CysArg: 0.639 ± 0.013	0.916CysSer: 0.916 ± 0.02	0.636CysThr: 0.636 ± 0.02	0.681CysVal: 0.681 ± 0.014	0.158CysTrp: 0.158 ± 0.006	0.269CysTyr: 0.269 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.819AspAla: 4.819 ± 0.038	0.508AspCys: 0.508 ± 0.01	4.925AspAsp: 4.925 ± 0.062	4.963AspGlu: 4.963 ± 0.048	1.836AspPhe: 1.836 ± 0.024	3.871AspGly: 3.871 ± 0.034	1.348AspHis: 1.348 ± 0.019	1.926AspIle: 1.926 ± 0.024	2.049AspLys: 2.049 ± 0.026	5.192AspLeu: 5.192 ± 0.04	0.891AspMet: 0.891 ± 0.014	1.272AspAsn: 1.272 ± 0.02	3.482AspPro: 3.482 ± 0.03	2.018AspGln: 2.018 ± 0.022	3.265AspArg: 3.265 ± 0.034	4.121AspSer: 4.121 ± 0.034	2.432AspThr: 2.432 ± 0.026	3.466AspVal: 3.466 ± 0.029	0.789AspTrp: 0.789 ± 0.013	1.319AspTyr: 1.319 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.756GluAla: 5.756 ± 0.045	0.528GluCys: 0.528 ± 0.012	4.095GluAsp: 4.095 ± 0.044	5.68GluGlu: 5.68 ± 0.057	1.657GluPhe: 1.657 ± 0.021	4.246GluGly: 4.246 ± 0.039	1.37GluHis: 1.37 ± 0.017	2.487GluIle: 2.487 ± 0.025	2.99GluLys: 2.99 ± 0.038	5.317GluLeu: 5.317 ± 0.046	1.468GluMet: 1.468 ± 0.02	1.645GluAsn: 1.645 ± 0.021	2.764GluPro: 2.764 ± 0.029	2.497GluGln: 2.497 ± 0.028	4.27GluArg: 4.27 ± 0.04	3.949GluSer: 3.949 ± 0.033	3.123GluThr: 3.123 ± 0.033	3.684GluVal: 3.684 ± 0.036	0.88GluTrp: 0.88 ± 0.015	1.298GluTyr: 1.298 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.232PheAla: 3.232 ± 0.029	0.429PheCys: 0.429 ± 0.011	2.254PheAsp: 2.254 ± 0.024	2.144PheGlu: 2.144 ± 0.024	1.312PhePhe: 1.312 ± 0.024	2.825PheGly: 2.825 ± 0.034	0.78PheHis: 0.78 ± 0.012	1.489PheIle: 1.489 ± 0.022	1.418PheLys: 1.418 ± 0.025	3.078PheLeu: 3.078 ± 0.031	0.567PheMet: 0.567 ± 0.012	1.141PheAsn: 1.141 ± 0.016	1.762PhePro: 1.762 ± 0.023	1.079PheGln: 1.079 ± 0.017	1.684PheArg: 1.684 ± 0.022	2.893PheSer: 2.893 ± 0.031	1.848PheThr: 1.848 ± 0.024	2.45PheVal: 2.45 ± 0.028	0.451PheTrp: 0.451 ± 0.012	0.865PheTyr: 0.865 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	6.291GlyAla: 6.291 ± 0.046	0.683GlyCys: 0.683 ± 0.014	3.421GlyAsp: 3.421 ± 0.031	3.848GlyGlu: 3.848 ± 0.031	2.502GlyPhe: 2.502 ± 0.029	6.704GlyGly: 6.704 ± 0.07	1.633GlyHis: 1.633 ± 0.022	2.874GlyIle: 2.874 ± 0.031	3.514GlyLys: 3.514 ± 0.035	5.984GlyLeu: 5.984 ± 0.047	1.521GlyMet: 1.521 ± 0.022	2.064GlyAsn: 2.064 ± 0.028	3.561GlyPro: 3.561 ± 0.034	2.537GlyGln: 2.537 ± 0.029	4.3GlyArg: 4.3 ± 0.043	6.591GlySer: 6.591 ± 0.061	4.118GlyThr: 4.118 ± 0.042	4.388GlyVal: 4.388 ± 0.037	1.053GlyTrp: 1.053 ± 0.017	1.698GlyTyr: 1.698 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.132HisAla: 2.132 ± 0.023	0.251HisCys: 0.251 ± 0.008	1.364HisAsp: 1.364 ± 0.019	1.29HisGlu: 1.29 ± 0.02	0.859HisPhe: 0.859 ± 0.015	1.548HisGly: 1.548 ± 0.02	1.091HisHis: 1.091 ± 0.026	0.901HisIle: 0.901 ± 0.015	0.776HisLys: 0.776 ± 0.014	2.531HisLeu: 2.531 ± 0.025	0.362HisMet: 0.362 ± 0.009	0.659HisAsn: 0.659 ± 0.014	1.849HisPro: 1.849 ± 0.023	1.053HisGln: 1.053 ± 0.019	1.667HisArg: 1.667 ± 0.022	2.136HisSer: 2.136 ± 0.027	1.221HisThr: 1.221 ± 0.02	1.45HisVal: 1.45 ± 0.017	0.261HisTrp: 0.261 ± 0.008	0.645HisTyr: 0.645 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.219IleAla: 4.219 ± 0.035	0.517IleCys: 0.517 ± 0.012	2.685IleAsp: 2.685 ± 0.028	2.886IleGlu: 2.886 ± 0.032	1.487IlePhe: 1.487 ± 0.023	2.804IleGly: 2.804 ± 0.029	0.947IleHis: 0.947 ± 0.016	1.9IleIle: 1.9 ± 0.021	2.055IleLys: 2.055 ± 0.027	3.743IleLeu: 3.743 ± 0.038	0.765IleMet: 0.765 ± 0.016	1.408IleAsn: 1.408 ± 0.018	2.644IlePro: 2.644 ± 0.031	1.465IleGln: 1.465 ± 0.02	2.463IleArg: 2.463 ± 0.024	3.354IleSer: 3.354 ± 0.03	2.321IleThr: 2.321 ± 0.027	3.137IleVal: 3.137 ± 0.032	0.532IleTrp: 0.532 ± 0.013	1.024IleTyr: 1.024 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.456LysAla: 4.456 ± 0.045	0.427LysCys: 0.427 ± 0.013	2.392LysAsp: 2.392 ± 0.026	3.081LysGlu: 3.081 ± 0.033	1.209LysPhe: 1.209 ± 0.02	3.233LysGly: 3.233 ± 0.035	0.951LysHis: 0.951 ± 0.016	1.944LysIle: 1.944 ± 0.026	3.202LysLys: 3.202 ± 0.048	3.839LysLeu: 3.839 ± 0.033	0.984LysMet: 0.984 ± 0.018	1.393LysAsn: 1.393 ± 0.019	2.397LysPro: 2.397 ± 0.028	1.619LysGln: 1.619 ± 0.023	3.464LysArg: 3.464 ± 0.032	3.267LysSer: 3.267 ± 0.032	2.706LysThr: 2.706 ± 0.029	2.901LysVal: 2.901 ± 0.028	0.576LysTrp: 0.576 ± 0.014	0.988LysTyr: 0.988 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.912LeuAla: 8.912 ± 0.063	1.034LeuCys: 1.034 ± 0.016	5.36LeuAsp: 5.36 ± 0.036	5.51LeuGlu: 5.51 ± 0.047	3.178LeuPhe: 3.178 ± 0.032	6.278LeuGly: 6.278 ± 0.041	2.233LeuHis: 2.233 ± 0.025	3.754LeuIle: 3.754 ± 0.039	3.997LeuLys: 3.997 ± 0.036	8.729LeuLeu: 8.729 ± 0.069	1.647LeuMet: 1.647 ± 0.023	2.904LeuAsn: 2.904 ± 0.029	6.042LeuPro: 6.042 ± 0.039	3.414LeuGln: 3.414 ± 0.035	5.846LeuArg: 5.846 ± 0.045	8.261LeuSer: 8.261 ± 0.046	5.105LeuThr: 5.105 ± 0.042	5.99LeuVal: 5.99 ± 0.049	1.013LeuTrp: 1.013 ± 0.018	2.058LeuTyr: 2.058 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.902MetAla: 1.902 ± 0.021	0.2MetCys: 0.2 ± 0.008	1.042MetAsp: 1.042 ± 0.017	1.015MetGlu: 1.015 ± 0.016	0.607MetPhe: 0.607 ± 0.013	1.362MetGly: 1.362 ± 0.019	0.432MetHis: 0.432 ± 0.01	0.848MetIle: 0.848 ± 0.014	0.797MetLys: 0.797 ± 0.015	1.721MetLeu: 1.721 ± 0.021	0.536MetMet: 0.536 ± 0.011	0.629MetAsn: 0.629 ± 0.013	1.136MetPro: 1.136 ± 0.018	0.754MetGln: 0.754 ± 0.012	1.266MetArg: 1.266 ± 0.017	1.927MetSer: 1.927 ± 0.024	1.332MetThr: 1.332 ± 0.019	1.134MetVal: 1.134 ± 0.018	0.22MetTrp: 0.22 ± 0.008	0.419MetTyr: 0.419 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.071AsnAla: 3.071 ± 0.032	0.334AsnCys: 0.334 ± 0.018	1.765AsnAsp: 1.765 ± 0.021	1.864AsnGlu: 1.864 ± 0.021	1.021AsnPhe: 1.021 ± 0.018	2.711AsnGly: 2.711 ± 0.034	0.743AsnHis: 0.743 ± 0.013	1.221AsnIle: 1.221 ± 0.016	1.411AsnLys: 1.411 ± 0.022	2.886AsnLeu: 2.886 ± 0.027	0.533AsnMet: 0.533 ± 0.012	1.065AsnAsn: 1.065 ± 0.021	2.155AsnPro: 2.155 ± 0.025	1.073AsnGln: 1.073 ± 0.018	1.749AsnArg: 1.749 ± 0.021	2.666AsnSer: 2.666 ± 0.032	1.692AsnThr: 1.692 ± 0.023	2.001AsnVal: 2.001 ± 0.023	0.389AsnTrp: 0.389 ± 0.007	0.757AsnTyr: 0.757 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.891ProAla: 5.891 ± 0.058	0.477ProCys: 0.477 ± 0.013	2.651ProAsp: 2.651 ± 0.031	3.042ProGlu: 3.042 ± 0.03	2.16ProPhe: 2.16 ± 0.025	3.537ProGly: 3.537 ± 0.043	1.57ProHis: 1.57 ± 0.021	2.789ProIle: 2.789 ± 0.026	2.525ProLys: 2.525 ± 0.029	5.645ProLeu: 5.645 ± 0.042	1.043ProMet: 1.043 ± 0.016	2.138ProAsn: 2.138 ± 0.024	6.49ProPro: 6.49 ± 0.082	2.181ProGln: 2.181 ± 0.027	3.909ProArg: 3.909 ± 0.041	8.371ProSer: 8.371 ± 0.085	5.352ProThr: 5.352 ± 0.051	3.599ProVal: 3.599 ± 0.032	0.606ProTrp: 0.606 ± 0.013	1.352ProTyr: 1.352 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.905GlnAla: 3.905 ± 0.039	0.348GlnCys: 0.348 ± 0.01	1.903GlnAsp: 1.903 ± 0.027	2.085GlnGlu: 2.085 ± 0.023	1.069GlnPhe: 1.069 ± 0.016	2.483GlnGly: 2.483 ± 0.028	1.17GlnHis: 1.17 ± 0.021	1.61GlnIle: 1.61 ± 0.02	1.452GlnLys: 1.452 ± 0.02	3.497GlnLeu: 3.497 ± 0.032	0.743GlnMet: 0.743 ± 0.015	1.097GlnAsn: 1.097 ± 0.017	2.311GlnPro: 2.311 ± 0.032	2.601GlnGln: 2.601 ± 0.085	2.647GlnArg: 2.647 ± 0.03	2.922GlnSer: 2.922 ± 0.031	2.083GlnThr: 2.083 ± 0.023	2.349GlnVal: 2.349 ± 0.028	0.436GlnTrp: 0.436 ± 0.01	0.845GlnTyr: 0.845 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.666ArgAla: 5.666 ± 0.048	0.671ArgCys: 0.671 ± 0.012	3.155ArgAsp: 3.155 ± 0.037	3.692ArgGlu: 3.692 ± 0.038	2.124ArgPhe: 2.124 ± 0.023	4.066ArgGly: 4.066 ± 0.039	1.555ArgHis: 1.555 ± 0.021	2.849ArgIle: 2.849 ± 0.029	3.3ArgLys: 3.3 ± 0.031	5.807ArgLeu: 5.807 ± 0.041	1.341ArgMet: 1.341 ± 0.018	1.967ArgAsn: 1.967 ± 0.024	3.956ArgPro: 3.956 ± 0.04	2.419ArgGln: 2.419 ± 0.023	5.507ArgArg: 5.507 ± 0.057	6.107ArgSer: 6.107 ± 0.06	3.759ArgThr: 3.759 ± 0.031	3.546ArgVal: 3.546 ± 0.035	0.845ArgTrp: 0.845 ± 0.014	1.433ArgTyr: 1.433 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	8.865SerAla: 8.865 ± 0.071	0.846SerCys: 0.846 ± 0.022	4.349SerAsp: 4.349 ± 0.042	4.048SerGlu: 4.048 ± 0.033	3.252SerPhe: 3.252 ± 0.029	6.061SerGly: 6.061 ± 0.051	2.233SerHis: 2.233 ± 0.026	4.119SerIle: 4.119 ± 0.029	3.778SerLys: 3.778 ± 0.033	8.41SerLeu: 8.41 ± 0.057	1.716SerMet: 1.716 ± 0.02	3.324SerAsn: 3.324 ± 0.034	6.993SerPro: 6.993 ± 0.078	3.003SerGln: 3.003 ± 0.03	5.63SerArg: 5.63 ± 0.053	14.122SerSer: 14.122 ± 0.135	8.573SerThr: 8.573 ± 0.077	4.862SerVal: 4.862 ± 0.04	0.962SerTrp: 0.962 ± 0.014	1.934SerTyr: 1.934 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	5.688ThrAla: 5.688 ± 0.044	0.727ThrCys: 0.727 ± 0.019	2.562ThrAsp: 2.562 ± 0.027	2.791ThrGlu: 2.791 ± 0.028	2.221ThrPhe: 2.221 ± 0.024	4.013ThrGly: 4.013 ± 0.036	1.34ThrHis: 1.34 ± 0.02	2.905ThrIle: 2.905 ± 0.032	2.628ThrLys: 2.628 ± 0.029	5.812ThrLeu: 5.812 ± 0.039	1.175ThrMet: 1.175 ± 0.018	2.058ThrAsn: 2.058 ± 0.024	5.191ThrPro: 5.191 ± 0.052	1.994ThrGln: 1.994 ± 0.022	3.745ThrArg: 3.745 ± 0.031	7.813ThrSer: 7.813 ± 0.067	5.843ThrThr: 5.843 ± 0.072	3.485ThrVal: 3.485 ± 0.031	0.749ThrTrp: 0.749 ± 0.015	1.368ThrTyr: 1.368 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.947ValAla: 5.947 ± 0.046	0.727ValCys: 0.727 ± 0.025	3.759ValAsp: 3.759 ± 0.032	4.264ValGlu: 4.264 ± 0.039	2.149ValPhe: 2.149 ± 0.029	4.265ValGly: 4.265 ± 0.035	1.393ValHis: 1.393 ± 0.021	2.593ValIle: 2.593 ± 0.03	2.883ValLys: 2.883 ± 0.03	5.779ValLeu: 5.779 ± 0.046	1.184ValMet: 1.184 ± 0.016	1.853ValAsn: 1.853 ± 0.024	3.783ValPro: 3.783 ± 0.032	2.331ValGln: 2.331 ± 0.027	3.61ValArg: 3.61 ± 0.032	4.515ValSer: 4.515 ± 0.035	3.296ValThr: 3.296 ± 0.032	4.644ValVal: 4.644 ± 0.04	0.805ValTrp: 0.805 ± 0.013	1.424ValTyr: 1.424 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.013TrpAla: 1.013 ± 0.014	0.165TrpCys: 0.165 ± 0.006	0.781TrpAsp: 0.781 ± 0.014	0.706TrpGlu: 0.706 ± 0.012	0.438TrpPhe: 0.438 ± 0.01	0.772TrpGly: 0.772 ± 0.015	0.28TrpHis: 0.28 ± 0.007	0.659TrpIle: 0.659 ± 0.014	0.638TrpLys: 0.638 ± 0.013	1.128TrpLeu: 1.128 ± 0.018	0.264TrpMet: 0.264 ± 0.008	0.486TrpAsn: 0.486 ± 0.012	0.504TrpPro: 0.504 ± 0.011	0.434TrpGln: 0.434 ± 0.01	0.83TrpArg: 0.83 ± 0.014	1.111TrpSer: 1.111 ± 0.017	0.869TrpThr: 0.869 ± 0.015	0.753TrpVal: 0.753 ± 0.015	0.226TrpTrp: 0.226 ± 0.007	0.311TrpTyr: 0.311 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.081TyrAla: 2.081 ± 0.026	0.3TyrCys: 0.3 ± 0.009	1.481TyrAsp: 1.481 ± 0.023	1.268TyrGlu: 1.268 ± 0.018	0.916TyrPhe: 0.916 ± 0.016	1.696TyrGly: 1.696 ± 0.027	0.619TyrHis: 0.619 ± 0.012	0.977TyrIle: 0.977 ± 0.018	0.89TyrLys: 0.89 ± 0.015	2.346TyrLeu: 2.346 ± 0.029	0.376TyrMet: 0.376 ± 0.009	0.78TyrAsn: 0.78 ± 0.015	1.278TyrPro: 1.278 ± 0.019	0.857TyrGln: 0.857 ± 0.014	1.422TyrArg: 1.422 ± 0.02	1.793TyrSer: 1.793 ± 0.023	1.31TyrThr: 1.31 ± 0.02	1.353TyrVal: 1.353 ± 0.018	0.312TyrTrp: 0.312 ± 0.009	0.704TyrTyr: 0.704 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7656 proteins (4103797 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---