Amino acid dipepetide frequency for Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.618AlaAla: 6.618 ± 0.032	1.377AlaCys: 1.377 ± 0.01	2.922AlaAsp: 2.922 ± 0.013	4.8AlaGlu: 4.8 ± 0.025	2.619AlaPhe: 2.619 ± 0.013	4.674AlaGly: 4.674 ± 0.022	1.547AlaHis: 1.547 ± 0.01	2.784AlaIle: 2.784 ± 0.012	3.473AlaLys: 3.473 ± 0.018	7.047AlaLeu: 7.047 ± 0.028	1.491AlaMet: 1.491 ± 0.009	2.029AlaAsn: 2.029 ± 0.009	4.085AlaPro: 4.085 ± 0.022	3.281AlaGln: 3.281 ± 0.017	3.624AlaArg: 3.624 ± 0.014	5.689AlaSer: 5.689 ± 0.024	3.635AlaThr: 3.635 ± 0.017	4.678AlaVal: 4.678 ± 0.017	0.811AlaTrp: 0.811 ± 0.007	1.521AlaTyr: 1.521 ± 0.008	0.002AlaXaa: 0.002 ± 0.0
Cys	1.214CysAla: 1.214 ± 0.009	0.636CysCys: 0.636 ± 0.007	0.999CysAsp: 0.999 ± 0.009	1.313CysGlu: 1.313 ± 0.013	0.831CysPhe: 0.831 ± 0.006	1.741CysGly: 1.741 ± 0.017	0.671CysHis: 0.671 ± 0.007	0.95CysIle: 0.95 ± 0.009	1.182CysLys: 1.182 ± 0.01	2.18CysLeu: 2.18 ± 0.014	0.417CysMet: 0.417 ± 0.005	0.82CysAsn: 0.82 ± 0.007	1.372CysPro: 1.372 ± 0.014	1.065CysGln: 1.065 ± 0.011	1.275CysArg: 1.275 ± 0.01	1.983CysSer: 1.983 ± 0.013	1.08CysThr: 1.08 ± 0.008	1.286CysVal: 1.286 ± 0.01	0.294CysTrp: 0.294 ± 0.004	0.566CysTyr: 0.566 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	2.88AspAla: 2.88 ± 0.012	1.056AspCys: 1.056 ± 0.009	2.659AspAsp: 2.659 ± 0.014	3.507AspGlu: 3.507 ± 0.017	2.123AspPhe: 2.123 ± 0.012	3.321AspGly: 3.321 ± 0.019	1.134AspHis: 1.134 ± 0.007	2.618AspIle: 2.618 ± 0.012	2.57AspLys: 2.57 ± 0.013	5.009AspLeu: 5.009 ± 0.019	1.117AspMet: 1.117 ± 0.007	1.693AspAsn: 1.693 ± 0.011	2.908AspPro: 2.908 ± 0.012	1.839AspGln: 1.839 ± 0.011	2.441AspArg: 2.441 ± 0.013	4.19AspSer: 4.19 ± 0.017	2.466AspThr: 2.466 ± 0.012	3.114AspVal: 3.114 ± 0.016	0.625AspTrp: 0.625 ± 0.005	1.498AspTyr: 1.498 ± 0.009	0.001AspXaa: 0.001 ± 0.0
Glu	5.29GluAla: 5.29 ± 0.026	1.491GluCys: 1.491 ± 0.019	4.515GluAsp: 4.515 ± 0.02	8.116GluGlu: 8.116 ± 0.047	2.062GluPhe: 2.062 ± 0.01	4.224GluGly: 4.224 ± 0.019	1.537GluHis: 1.537 ± 0.008	3.203GluIle: 3.203 ± 0.018	5.54GluLys: 5.54 ± 0.03	6.554GluLeu: 6.554 ± 0.028	1.713GluMet: 1.713 ± 0.01	3.185GluAsn: 3.185 ± 0.015	3.255GluPro: 3.255 ± 0.024	3.187GluGln: 3.187 ± 0.018	4.065GluArg: 4.065 ± 0.02	4.407GluSer: 4.407 ± 0.016	3.428GluThr: 3.428 ± 0.015	4.237GluVal: 4.237 ± 0.02	0.706GluTrp: 0.706 ± 0.006	1.634GluTyr: 1.634 ± 0.013	0.002GluXaa: 0.002 ± 0.0
Phe	1.959PheAla: 1.959 ± 0.01	0.907PheCys: 0.907 ± 0.007	1.689PheAsp: 1.689 ± 0.009	2.04PheGlu: 2.04 ± 0.01	1.551PhePhe: 1.551 ± 0.01	2.196PheGly: 2.196 ± 0.012	1.048PheHis: 1.048 ± 0.008	1.783PheIle: 1.783 ± 0.011	1.822PheLys: 1.822 ± 0.012	4.001PheLeu: 4.001 ± 0.02	0.766PheMet: 0.766 ± 0.006	1.34PheAsn: 1.34 ± 0.009	1.99PhePro: 1.99 ± 0.011	1.803PheGln: 1.803 ± 0.008	1.986PheArg: 1.986 ± 0.014	3.374PheSer: 3.374 ± 0.016	2.029PheThr: 2.029 ± 0.01	2.11PheVal: 2.11 ± 0.011	0.478PheTrp: 0.478 ± 0.005	1.145PheTyr: 1.145 ± 0.007	0.001PheXaa: 0.001 ± 0.0
Gly	4.407GlyAla: 4.407 ± 0.022	1.254GlyCys: 1.254 ± 0.009	3.15GlyAsp: 3.15 ± 0.016	4.196GlyGlu: 4.196 ± 0.021	2.381GlyPhe: 2.381 ± 0.016	4.968GlyGly: 4.968 ± 0.03	1.699GlyHis: 1.699 ± 0.01	2.765GlyIle: 2.765 ± 0.013	3.898GlyLys: 3.898 ± 0.023	5.843GlyLeu: 5.843 ± 0.026	1.318GlyMet: 1.318 ± 0.009	2.346GlyAsn: 2.346 ± 0.012	4.207GlyPro: 4.207 ± 0.039	2.756GlyGln: 2.756 ± 0.015	3.753GlyArg: 3.753 ± 0.017	5.801GlySer: 5.801 ± 0.025	3.582GlyThr: 3.582 ± 0.017	3.567GlyVal: 3.567 ± 0.018	0.794GlyTrp: 0.794 ± 0.007	1.726GlyTyr: 1.726 ± 0.011	0.001GlyXaa: 0.001 ± 0.0
His	1.317HisAla: 1.317 ± 0.008	0.734HisCys: 0.734 ± 0.006	0.892HisAsp: 0.892 ± 0.006	1.356HisGlu: 1.356 ± 0.009	1.083HisPhe: 1.083 ± 0.007	1.546HisGly: 1.546 ± 0.011	0.913HisHis: 0.913 ± 0.01	1.248HisIle: 1.248 ± 0.008	1.295HisLys: 1.295 ± 0.01	2.931HisLeu: 2.931 ± 0.014	0.592HisMet: 0.592 ± 0.006	0.874HisAsn: 0.874 ± 0.006	1.658HisPro: 1.658 ± 0.011	1.374HisGln: 1.374 ± 0.012	1.603HisArg: 1.603 ± 0.01	2.318HisSer: 2.318 ± 0.013	1.58HisThr: 1.58 ± 0.012	1.487HisVal: 1.487 ± 0.009	0.357HisTrp: 0.357 ± 0.004	0.794HisTyr: 0.794 ± 0.006	0.001HisXaa: 0.001 ± 0.0
Ile	2.586IleAla: 2.586 ± 0.012	1.069IleCys: 1.069 ± 0.008	2.017IleAsp: 2.017 ± 0.011	2.645IleGlu: 2.645 ± 0.017	1.863IlePhe: 1.863 ± 0.014	2.216IleGly: 2.216 ± 0.011	1.404IleHis: 1.404 ± 0.011	2.367IleIle: 2.367 ± 0.016	2.684IleLys: 2.684 ± 0.016	4.531IleLeu: 4.531 ± 0.017	0.99IleMet: 0.99 ± 0.007	1.825IleAsn: 1.825 ± 0.01	2.606IlePro: 2.606 ± 0.013	2.309IleGln: 2.309 ± 0.012	2.377IleArg: 2.377 ± 0.011	3.699IleSer: 3.699 ± 0.016	2.574IleThr: 2.574 ± 0.018	2.507IleVal: 2.507 ± 0.017	0.511IleTrp: 0.511 ± 0.005	1.368IleTyr: 1.368 ± 0.009	0.001IleXaa: 0.001 ± 0.0
Lys	4.091LysAla: 4.091 ± 0.021	1.197LysCys: 1.197 ± 0.012	3.206LysAsp: 3.206 ± 0.02	5.24LysGlu: 5.24 ± 0.028	1.752LysPhe: 1.752 ± 0.01	3.28LysGly: 3.28 ± 0.019	1.42LysHis: 1.42 ± 0.009	2.853LysIle: 2.853 ± 0.016	4.789LysLys: 4.789 ± 0.027	5.217LysLeu: 5.217 ± 0.021	1.45LysMet: 1.45 ± 0.01	2.435LysAsn: 2.435 ± 0.013	3.206LysPro: 3.206 ± 0.025	2.644LysGln: 2.644 ± 0.015	3.336LysArg: 3.336 ± 0.016	3.914LysSer: 3.914 ± 0.019	3.14LysThr: 3.14 ± 0.016	3.55LysVal: 3.55 ± 0.023	0.61LysTrp: 0.61 ± 0.007	1.594LysTyr: 1.594 ± 0.012	0.001LysXaa: 0.001 ± 0.0
Leu	6.734LeuAla: 6.734 ± 0.025	2.173LeuCys: 2.173 ± 0.013	4.728LeuAsp: 4.728 ± 0.019	7.244LeuGlu: 7.244 ± 0.032	3.324LeuPhe: 3.324 ± 0.015	5.836LeuGly: 5.836 ± 0.026	2.713LeuHis: 2.713 ± 0.014	3.843LeuIle: 3.843 ± 0.018	5.876LeuLys: 5.876 ± 0.023	10.654LeuLeu: 10.654 ± 0.043	2.011LeuMet: 2.011 ± 0.011	3.484LeuAsn: 3.484 ± 0.016	5.987LeuPro: 5.987 ± 0.025	5.828LeuGln: 5.828 ± 0.029	5.888LeuArg: 5.888 ± 0.025	7.897LeuSer: 7.897 ± 0.027	5.079LeuThr: 5.079 ± 0.019	5.476LeuVal: 5.476 ± 0.02	1.139LeuTrp: 1.139 ± 0.008	2.504LeuTyr: 2.504 ± 0.01	0.003LeuXaa: 0.003 ± 0.0
Met	1.917MetAla: 1.917 ± 0.01	0.402MetCys: 0.402 ± 0.004	1.265MetAsp: 1.265 ± 0.007	1.896MetGlu: 1.896 ± 0.012	0.722MetPhe: 0.722 ± 0.005	1.298MetGly: 1.298 ± 0.01	0.474MetHis: 0.474 ± 0.005	0.845MetIle: 0.845 ± 0.007	1.462MetLys: 1.462 ± 0.008	1.967MetLeu: 1.967 ± 0.01	0.566MetMet: 0.566 ± 0.006	0.898MetAsn: 0.898 ± 0.007	1.105MetPro: 1.105 ± 0.011	0.933MetGln: 0.933 ± 0.007	1.056MetArg: 1.056 ± 0.007	1.555MetSer: 1.555 ± 0.009	1.116MetThr: 1.116 ± 0.008	1.39MetVal: 1.39 ± 0.007	0.237MetTrp: 0.237 ± 0.003	0.546MetTyr: 0.546 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.065AsnAla: 2.065 ± 0.011	0.836AsnCys: 0.836 ± 0.008	1.537AsnAsp: 1.537 ± 0.01	2.271AsnGlu: 2.271 ± 0.012	1.47AsnPhe: 1.47 ± 0.01	2.446AsnGly: 2.446 ± 0.015	0.947AsnHis: 0.947 ± 0.008	2.121AsnIle: 2.121 ± 0.012	2.239AsnLys: 2.239 ± 0.012	3.742AsnLeu: 3.742 ± 0.017	0.907AsnMet: 0.907 ± 0.007	1.524AsnAsn: 1.524 ± 0.01	2.171AsnPro: 2.171 ± 0.012	1.67AsnGln: 1.67 ± 0.01	1.848AsnArg: 1.848 ± 0.009	3.134AsnSer: 3.134 ± 0.015	1.96AsnThr: 1.96 ± 0.01	2.201AsnVal: 2.201 ± 0.011	0.454AsnTrp: 0.454 ± 0.004	1.122AsnTyr: 1.122 ± 0.007	0.001AsnXaa: 0.001 ± 0.0
Pro	4.794ProAla: 4.794 ± 0.024	1.134ProCys: 1.134 ± 0.01	2.795ProAsp: 2.795 ± 0.015	4.466ProGlu: 4.466 ± 0.024	1.905ProPhe: 1.905 ± 0.011	5.191ProGly: 5.191 ± 0.048	1.457ProHis: 1.457 ± 0.011	1.912ProIle: 1.912 ± 0.014	2.81ProLys: 2.81 ± 0.019	5.224ProLeu: 5.224 ± 0.021	1.025ProMet: 1.025 ± 0.008	1.832ProAsn: 1.832 ± 0.011	6.003ProPro: 6.003 ± 0.054	2.846ProGln: 2.846 ± 0.018	3.303ProArg: 3.303 ± 0.02	5.709ProSer: 5.709 ± 0.028	3.164ProThr: 3.164 ± 0.018	3.83ProVal: 3.83 ± 0.02	0.698ProTrp: 0.698 ± 0.007	1.566ProTyr: 1.566 ± 0.013	0.003ProXaa: 0.003 ± 0.0
Gln	3.566GlnAla: 3.566 ± 0.019	0.949GlnCys: 0.949 ± 0.009	2.351GlnAsp: 2.351 ± 0.012	3.981GlnGlu: 3.981 ± 0.022	1.387GlnPhe: 1.387 ± 0.009	2.87GlnGly: 2.87 ± 0.016	1.32GlnHis: 1.32 ± 0.009	1.993GlnIle: 1.993 ± 0.01	3.003GlnLys: 3.003 ± 0.015	4.753GlnLeu: 4.753 ± 0.023	1.121GlnMet: 1.121 ± 0.008	1.869GlnAsn: 1.869 ± 0.01	2.811GlnPro: 2.811 ± 0.018	3.176GlnGln: 3.176 ± 0.027	2.989GlnArg: 2.989 ± 0.014	3.157GlnSer: 3.157 ± 0.015	2.299GlnThr: 2.299 ± 0.013	2.825GlnVal: 2.825 ± 0.012	0.55GlnTrp: 0.55 ± 0.005	1.159GlnTyr: 1.159 ± 0.007	0.001GlnXaa: 0.001 ± 0.0
Arg	3.781ArgAla: 3.781 ± 0.018	1.217ArgCys: 1.217 ± 0.011	2.777ArgAsp: 2.777 ± 0.013	4.041ArgGlu: 4.041 ± 0.019	1.839ArgPhe: 1.839 ± 0.009	3.603ArgGly: 3.603 ± 0.024	1.557ArgHis: 1.557 ± 0.011	2.471ArgIle: 2.471 ± 0.015	3.688ArgLys: 3.688 ± 0.016	5.417ArgLeu: 5.417 ± 0.021	1.216ArgMet: 1.216 ± 0.008	2.115ArgAsn: 2.115 ± 0.01	3.196ArgPro: 3.196 ± 0.016	2.649ArgGln: 2.649 ± 0.015	4.284ArgArg: 4.284 ± 0.023	4.229ArgSer: 4.229 ± 0.026	2.811ArgThr: 2.811 ± 0.012	3.163ArgVal: 3.163 ± 0.02	0.691ArgTrp: 0.691 ± 0.006	1.431ArgTyr: 1.431 ± 0.008	0.002ArgXaa: 0.002 ± 0.0
Ser	5.27SerAla: 5.27 ± 0.018	1.822SerCys: 1.822 ± 0.012	3.891SerAsp: 3.891 ± 0.019	5.211SerGlu: 5.211 ± 0.023	3.015SerPhe: 3.015 ± 0.013	5.593SerGly: 5.593 ± 0.028	2.147SerHis: 2.147 ± 0.011	3.201SerIle: 3.201 ± 0.013	4.106SerLys: 4.106 ± 0.019	8.156SerLeu: 8.156 ± 0.029	1.616SerMet: 1.616 ± 0.008	2.712SerAsn: 2.712 ± 0.014	6.015SerPro: 6.015 ± 0.031	3.885SerGln: 3.885 ± 0.018	4.515SerArg: 4.515 ± 0.025	9.345SerSer: 9.345 ± 0.051	4.455SerThr: 4.455 ± 0.024	4.848SerVal: 4.848 ± 0.018	1.08SerTrp: 1.08 ± 0.009	2.057SerTyr: 2.057 ± 0.012	0.002SerXaa: 0.002 ± 0.0
Thr	3.758ThrAla: 3.758 ± 0.017	1.28ThrCys: 1.28 ± 0.013	2.459ThrAsp: 2.459 ± 0.011	3.534ThrGlu: 3.534 ± 0.014	2.083ThrPhe: 2.083 ± 0.01	3.624ThrGly: 3.624 ± 0.019	1.336ThrHis: 1.336 ± 0.009	2.37ThrIle: 2.37 ± 0.014	2.698ThrLys: 2.698 ± 0.017	5.272ThrLeu: 5.272 ± 0.017	1.115ThrMet: 1.115 ± 0.007	1.757ThrAsn: 1.757 ± 0.009	3.624ThrPro: 3.624 ± 0.023	2.315ThrGln: 2.315 ± 0.011	2.453ThrArg: 2.453 ± 0.012	4.649ThrSer: 4.649 ± 0.025	3.045ThrThr: 3.045 ± 0.027	3.833ThrVal: 3.833 ± 0.022	0.7ThrTrp: 0.7 ± 0.008	1.414ThrTyr: 1.414 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	4.276ValAla: 4.276 ± 0.018	1.421ValCys: 1.421 ± 0.01	2.981ValAsp: 2.981 ± 0.015	3.92ValGlu: 3.92 ± 0.02	2.374ValPhe: 2.374 ± 0.013	3.385ValGly: 3.385 ± 0.016	1.564ValHis: 1.564 ± 0.008	2.901ValIle: 2.901 ± 0.015	3.445ValLys: 3.445 ± 0.022	6.107ValLeu: 6.107 ± 0.019	1.31ValMet: 1.31 ± 0.008	2.282ValAsn: 2.282 ± 0.012	3.646ValPro: 3.646 ± 0.022	2.764ValGln: 2.764 ± 0.012	3.037ValArg: 3.037 ± 0.015	4.84ValSer: 4.84 ± 0.016	3.774ValThr: 3.774 ± 0.027	3.959ValVal: 3.959 ± 0.02	0.717ValTrp: 0.717 ± 0.006	1.602ValTyr: 1.602 ± 0.009	0.001ValXaa: 0.001 ± 0.0
Trp	0.793TrpAla: 0.793 ± 0.005	0.248TrpCys: 0.248 ± 0.003	0.653TrpAsp: 0.653 ± 0.006	0.831TrpGlu: 0.831 ± 0.006	0.444TrpPhe: 0.444 ± 0.005	0.736TrpGly: 0.736 ± 0.008	0.31TrpHis: 0.31 ± 0.004	0.541TrpIle: 0.541 ± 0.005	0.821TrpLys: 0.821 ± 0.006	1.206TrpLeu: 1.206 ± 0.008	0.318TrpMet: 0.318 ± 0.004	0.54TrpAsn: 0.54 ± 0.005	0.527TrpPro: 0.527 ± 0.006	0.539TrpGln: 0.539 ± 0.005	0.729TrpArg: 0.729 ± 0.007	0.885TrpSer: 0.885 ± 0.007	0.667TrpThr: 0.667 ± 0.006	0.684TrpVal: 0.684 ± 0.007	0.193TrpTrp: 0.193 ± 0.003	0.334TrpTyr: 0.334 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.388TyrAla: 1.388 ± 0.009	0.672TyrCys: 0.672 ± 0.006	1.281TyrAsp: 1.281 ± 0.009	1.741TyrGlu: 1.741 ± 0.011	1.192TyrPhe: 1.192 ± 0.008	1.662TyrGly: 1.662 ± 0.012	0.757TyrHis: 0.757 ± 0.006	1.379TyrIle: 1.379 ± 0.01	1.523TyrLys: 1.523 ± 0.012	2.61TyrLeu: 2.61 ± 0.011	0.591TyrMet: 0.591 ± 0.005	1.101TyrAsn: 1.101 ± 0.009	1.291TyrPro: 1.291 ± 0.01	1.266TyrGln: 1.266 ± 0.009	1.612TyrArg: 1.612 ± 0.008	2.166TyrSer: 2.166 ± 0.012	1.435TyrThr: 1.435 ± 0.012	1.557TyrVal: 1.557 ± 0.009	0.356TyrTrp: 0.356 ± 0.005	0.931TyrTyr: 0.931 ± 0.008	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.003XaaGly: 0.003 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	1.027XaaXaa: 1.027 ± 0.062

Statistics based on 44577 proteins (23994639 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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