Amino acid dipepetide frequency for Dinoponera quadriceps (South American ant)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.516AlaAla: 6.516 ± 0.073	1.163AlaCys: 1.163 ± 0.019	3.56AlaAsp: 3.56 ± 0.024	4.701AlaGlu: 4.701 ± 0.041	2.044AlaPhe: 2.044 ± 0.019	4.076AlaGly: 4.076 ± 0.027	1.472AlaHis: 1.472 ± 0.013	3.338AlaIle: 3.338 ± 0.024	4.011AlaLys: 4.011 ± 0.062	5.979AlaLeu: 5.979 ± 0.036	1.602AlaMet: 1.602 ± 0.012	2.887AlaAsn: 2.887 ± 0.018	3.242AlaPro: 3.242 ± 0.027	2.832AlaGln: 2.832 ± 0.026	3.979AlaArg: 3.979 ± 0.028	5.719AlaSer: 5.719 ± 0.028	4.382AlaThr: 4.382 ± 0.024	4.489AlaVal: 4.489 ± 0.034	0.639AlaTrp: 0.639 ± 0.009	1.612AlaTyr: 1.612 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	1.128CysAla: 1.128 ± 0.016	0.451CysCys: 0.451 ± 0.009	1.15CysAsp: 1.15 ± 0.017	1.127CysGlu: 1.127 ± 0.016	0.638CysPhe: 0.638 ± 0.009	1.239CysGly: 1.239 ± 0.024	0.496CysHis: 0.496 ± 0.009	0.989CysIle: 0.989 ± 0.016	1.06CysLys: 1.06 ± 0.013	1.675CysLeu: 1.675 ± 0.02	0.393CysMet: 0.393 ± 0.006	0.905CysAsn: 0.905 ± 0.013	0.976CysPro: 0.976 ± 0.027	0.762CysGln: 0.762 ± 0.012	1.132CysArg: 1.132 ± 0.024	1.458CysSer: 1.458 ± 0.022	1.068CysThr: 1.068 ± 0.017	1.228CysVal: 1.228 ± 0.02	0.208CysTrp: 0.208 ± 0.005	0.544CysTyr: 0.544 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.733AspAla: 3.733 ± 0.039	0.973AspCys: 0.973 ± 0.018	3.997AspAsp: 3.997 ± 0.033	4.462AspGlu: 4.462 ± 0.029	1.966AspPhe: 1.966 ± 0.015	3.385AspGly: 3.385 ± 0.027	1.163AspHis: 1.163 ± 0.012	3.246AspIle: 3.246 ± 0.019	3.34AspLys: 3.34 ± 0.031	4.835AspLeu: 4.835 ± 0.027	1.269AspMet: 1.269 ± 0.011	2.588AspAsn: 2.588 ± 0.016	2.621AspPro: 2.621 ± 0.029	1.737AspGln: 1.737 ± 0.013	3.045AspArg: 3.045 ± 0.026	4.508AspSer: 4.508 ± 0.027	3.152AspThr: 3.152 ± 0.02	3.861AspVal: 3.861 ± 0.024	0.639AspTrp: 0.639 ± 0.008	1.732AspTyr: 1.732 ± 0.014	0.001AspXaa: 0.001 ± 0.0
Glu	4.748GluAla: 4.748 ± 0.046	1.197GluCys: 1.197 ± 0.025	4.493GluAsp: 4.493 ± 0.027	6.855GluGlu: 6.855 ± 0.062	2.004GluPhe: 2.004 ± 0.013	3.193GluGly: 3.193 ± 0.024	1.548GluHis: 1.548 ± 0.011	3.712GluIle: 3.712 ± 0.026	5.195GluLys: 5.195 ± 0.053	5.97GluLeu: 5.97 ± 0.041	1.673GluMet: 1.673 ± 0.013	3.476GluAsn: 3.476 ± 0.025	2.75GluPro: 2.75 ± 0.025	3.015GluGln: 3.015 ± 0.028	4.607GluArg: 4.607 ± 0.037	4.956GluSer: 4.956 ± 0.031	3.889GluThr: 3.889 ± 0.026	3.913GluVal: 3.913 ± 0.029	0.644GluTrp: 0.644 ± 0.008	1.897GluTyr: 1.897 ± 0.015	0.001GluXaa: 0.001 ± 0.0
Phe	2.073PheAla: 2.073 ± 0.017	0.699PheCys: 0.699 ± 0.01	1.859PheAsp: 1.859 ± 0.014	1.96PheGlu: 1.96 ± 0.015	1.285PhePhe: 1.285 ± 0.015	2.004PheGly: 2.004 ± 0.018	0.886PheHis: 0.886 ± 0.01	1.75PheIle: 1.75 ± 0.017	1.763PheLys: 1.763 ± 0.015	3.219PheLeu: 3.219 ± 0.023	0.737PheMet: 0.737 ± 0.009	1.492PheAsn: 1.492 ± 0.015	1.508PhePro: 1.508 ± 0.012	1.272PheGln: 1.272 ± 0.012	1.763PheArg: 1.763 ± 0.016	2.561PheSer: 2.561 ± 0.017	1.953PheThr: 1.953 ± 0.018	2.222PheVal: 2.222 ± 0.019	0.377PheTrp: 0.377 ± 0.006	1.102PheTyr: 1.102 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	3.67GlyAla: 3.67 ± 0.032	0.953GlyCys: 0.953 ± 0.015	3.09GlyAsp: 3.09 ± 0.021	3.507GlyGlu: 3.507 ± 0.026	1.982GlyPhe: 1.982 ± 0.016	4.802GlyGly: 4.802 ± 0.053	1.433GlyHis: 1.433 ± 0.014	2.921GlyIle: 2.921 ± 0.02	3.395GlyLys: 3.395 ± 0.018	4.512GlyLeu: 4.512 ± 0.028	1.267GlyMet: 1.267 ± 0.011	2.704GlyAsn: 2.704 ± 0.019	2.603GlyPro: 2.603 ± 0.037	2.229GlyGln: 2.229 ± 0.018	3.379GlyArg: 3.379 ± 0.021	4.978GlySer: 4.978 ± 0.033	3.319GlyThr: 3.319 ± 0.023	3.385GlyVal: 3.385 ± 0.024	0.615GlyTrp: 0.615 ± 0.008	1.848GlyTyr: 1.848 ± 0.021	0.001GlyXaa: 0.001 ± 0.0
His	1.514HisAla: 1.514 ± 0.013	0.573HisCys: 0.573 ± 0.008	1.146HisAsp: 1.146 ± 0.011	1.473HisGlu: 1.473 ± 0.011	0.87HisPhe: 0.87 ± 0.01	1.434HisGly: 1.434 ± 0.015	1.222HisHis: 1.222 ± 0.023	1.296HisIle: 1.296 ± 0.012	1.274HisLys: 1.274 ± 0.011	2.295HisLeu: 2.295 ± 0.019	0.615HisMet: 0.615 ± 0.007	1.118HisAsn: 1.118 ± 0.01	1.412HisPro: 1.412 ± 0.013	1.222HisGln: 1.222 ± 0.014	1.623HisArg: 1.623 ± 0.013	2.02HisSer: 2.02 ± 0.017	1.421HisThr: 1.421 ± 0.012	1.584HisVal: 1.584 ± 0.012	0.279HisTrp: 0.279 ± 0.005	0.803HisTyr: 0.803 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.592IleAla: 3.592 ± 0.021	1.103IleCys: 1.103 ± 0.015	2.959IleAsp: 2.959 ± 0.021	3.364IleGlu: 3.364 ± 0.026	1.928IlePhe: 1.928 ± 0.018	2.755IleGly: 2.755 ± 0.019	1.223IleHis: 1.223 ± 0.012	2.79IleIle: 2.79 ± 0.025	3.002IleLys: 3.002 ± 0.019	4.866IleLeu: 4.866 ± 0.029	1.159IleMet: 1.159 ± 0.012	2.368IleAsn: 2.368 ± 0.018	2.694IlePro: 2.694 ± 0.02	2.103IleGln: 2.103 ± 0.019	2.726IleArg: 2.726 ± 0.017	4.128IleSer: 4.128 ± 0.021	3.049IleThr: 3.049 ± 0.018	3.47IleVal: 3.47 ± 0.023	0.509IleTrp: 0.509 ± 0.008	1.544IleTyr: 1.544 ± 0.017	0.001IleXaa: 0.001 ± 0.0
Lys	3.578LysAla: 3.578 ± 0.036	1.109LysCys: 1.109 ± 0.016	3.642LysAsp: 3.642 ± 0.052	4.938LysGlu: 4.938 ± 0.061	1.839LysPhe: 1.839 ± 0.013	2.606LysGly: 2.606 ± 0.022	1.492LysHis: 1.492 ± 0.014	3.36LysIle: 3.36 ± 0.022	4.81LysLys: 4.81 ± 0.046	5.484LysLeu: 5.484 ± 0.035	1.477LysMet: 1.477 ± 0.012	2.815LysAsn: 2.815 ± 0.021	2.892LysPro: 2.892 ± 0.031	2.669LysGln: 2.669 ± 0.02	3.91LysArg: 3.91 ± 0.024	4.481LysSer: 4.481 ± 0.035	3.339LysThr: 3.339 ± 0.019	3.418LysVal: 3.418 ± 0.026	0.632LysTrp: 0.632 ± 0.008	1.886LysTyr: 1.886 ± 0.014	0.001LysXaa: 0.001 ± 0.0
Leu	6.124LeuAla: 6.124 ± 0.032	1.682LeuCys: 1.682 ± 0.014	4.871LeuAsp: 4.871 ± 0.032	6.36LeuGlu: 6.36 ± 0.045	2.816LeuPhe: 2.816 ± 0.024	4.383LeuGly: 4.383 ± 0.024	2.492LeuHis: 2.492 ± 0.017	4.153LeuIle: 4.153 ± 0.026	5.503LeuLys: 5.503 ± 0.032	8.702LeuLeu: 8.702 ± 0.054	2.001LeuMet: 2.001 ± 0.016	3.938LeuAsn: 3.938 ± 0.021	4.834LeuPro: 4.834 ± 0.027	4.712LeuGln: 4.712 ± 0.037	5.676LeuArg: 5.676 ± 0.027	7.12LeuSer: 7.12 ± 0.032	4.981LeuThr: 4.981 ± 0.02	5.031LeuVal: 5.031 ± 0.029	0.857LeuTrp: 0.857 ± 0.01	2.566LeuTyr: 2.566 ± 0.021	0.001LeuXaa: 0.001 ± 0.0
Met	1.605MetAla: 1.605 ± 0.013	0.415MetCys: 0.415 ± 0.007	1.322MetAsp: 1.322 ± 0.011	1.737MetGlu: 1.737 ± 0.016	0.79MetPhe: 0.79 ± 0.012	1.116MetGly: 1.116 ± 0.011	0.548MetHis: 0.548 ± 0.008	1.097MetIle: 1.097 ± 0.011	1.486MetLys: 1.486 ± 0.013	2.073MetLeu: 2.073 ± 0.015	0.672MetMet: 0.672 ± 0.009	1.037MetAsn: 1.037 ± 0.01	1.17MetPro: 1.17 ± 0.011	1.1MetGln: 1.1 ± 0.012	1.322MetArg: 1.322 ± 0.01	1.912MetSer: 1.912 ± 0.013	1.307MetThr: 1.307 ± 0.01	1.264MetVal: 1.264 ± 0.01	0.242MetTrp: 0.242 ± 0.005	0.683MetTyr: 0.683 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.157AsnAla: 3.157 ± 0.021	0.836AsnCys: 0.836 ± 0.014	2.568AsnAsp: 2.568 ± 0.017	3.031AsnGlu: 3.031 ± 0.021	1.537AsnPhe: 1.537 ± 0.014	2.915AsnGly: 2.915 ± 0.025	1.074AsnHis: 1.074 ± 0.011	2.804AsnIle: 2.804 ± 0.022	2.659AsnLys: 2.659 ± 0.019	4.129AsnLeu: 4.129 ± 0.021	1.098AsnMet: 1.098 ± 0.011	2.818AsnAsn: 2.818 ± 0.024	2.175AsnPro: 2.175 ± 0.019	1.77AsnGln: 1.77 ± 0.016	2.335AsnArg: 2.335 ± 0.015	3.702AsnSer: 3.702 ± 0.024	2.659AsnThr: 2.659 ± 0.02	3.303AsnVal: 3.303 ± 0.019	0.465AsnTrp: 0.465 ± 0.006	1.42AsnTyr: 1.42 ± 0.014	0.001AsnXaa: 0.001 ± 0.0
Pro	3.754ProAla: 3.754 ± 0.025	0.804ProCys: 0.804 ± 0.027	2.717ProAsp: 2.717 ± 0.019	3.421ProGlu: 3.421 ± 0.031	1.497ProPhe: 1.497 ± 0.014	3.273ProGly: 3.273 ± 0.05	1.329ProHis: 1.329 ± 0.013	2.401ProIle: 2.401 ± 0.015	2.668ProLys: 2.668 ± 0.022	4.206ProLeu: 4.206 ± 0.022	1.096ProMet: 1.096 ± 0.011	2.202ProAsn: 2.202 ± 0.018	4.93ProPro: 4.93 ± 0.061	2.3ProGln: 2.3 ± 0.025	2.956ProArg: 2.956 ± 0.023	4.867ProSer: 4.867 ± 0.04	3.464ProThr: 3.464 ± 0.028	3.424ProVal: 3.424 ± 0.022	0.476ProTrp: 0.476 ± 0.007	1.453ProTyr: 1.453 ± 0.015	0.001ProXaa: 0.001 ± 0.0
Gln	2.87GlnAla: 2.87 ± 0.021	0.805GlnCys: 0.805 ± 0.015	2.12GlnAsp: 2.12 ± 0.014	3.143GlnGlu: 3.143 ± 0.025	1.276GlnPhe: 1.276 ± 0.013	2.01GlnGly: 2.01 ± 0.019	1.372GlnHis: 1.372 ± 0.014	2.119GlnIle: 2.119 ± 0.017	2.429GlnLys: 2.429 ± 0.02	4.095GlnLeu: 4.095 ± 0.029	1.025GlnMet: 1.025 ± 0.012	2.061GlnAsn: 2.061 ± 0.016	2.402GlnPro: 2.402 ± 0.027	4.467GlnGln: 4.467 ± 0.081	2.951GlnArg: 2.951 ± 0.023	3.27GlnSer: 3.27 ± 0.026	2.368GlnThr: 2.368 ± 0.02	2.416GlnVal: 2.416 ± 0.018	0.464GlnTrp: 0.464 ± 0.008	1.254GlnTyr: 1.254 ± 0.014	0.001GlnXaa: 0.001 ± 0.0
Arg	3.739ArgAla: 3.739 ± 0.026	1.138ArgCys: 1.138 ± 0.018	3.456ArgAsp: 3.456 ± 0.026	4.338ArgGlu: 4.338 ± 0.03	1.883ArgPhe: 1.883 ± 0.015	3.221ArgGly: 3.221 ± 0.025	1.665ArgHis: 1.665 ± 0.013	2.954ArgIle: 2.954 ± 0.017	4.085ArgLys: 4.085 ± 0.026	5.284ArgLeu: 5.284 ± 0.027	1.254ArgMet: 1.254 ± 0.011	2.867ArgAsn: 2.867 ± 0.02	2.918ArgPro: 2.918 ± 0.03	2.645ArgGln: 2.645 ± 0.017	4.916ArgArg: 4.916 ± 0.037	4.999ArgSer: 4.999 ± 0.039	3.133ArgThr: 3.133 ± 0.016	3.233ArgVal: 3.233 ± 0.019	0.634ArgTrp: 0.634 ± 0.008	1.818ArgTyr: 1.818 ± 0.015	0.001ArgXaa: 0.001 ± 0.0
Ser	5.425SerAla: 5.425 ± 0.034	1.414SerCys: 1.414 ± 0.023	4.518SerAsp: 4.518 ± 0.025	4.931SerGlu: 4.931 ± 0.029	2.523SerPhe: 2.523 ± 0.018	5.166SerGly: 5.166 ± 0.034	1.924SerHis: 1.924 ± 0.017	3.825SerIle: 3.825 ± 0.021	4.453SerLys: 4.453 ± 0.027	7.154SerLeu: 7.154 ± 0.038	1.81SerMet: 1.81 ± 0.016	3.771SerAsn: 3.771 ± 0.027	5.303SerPro: 5.303 ± 0.046	3.508SerGln: 3.508 ± 0.024	4.974SerArg: 4.974 ± 0.039	9.437SerSer: 9.437 ± 0.065	5.507SerThr: 5.507 ± 0.042	4.968SerVal: 4.968 ± 0.026	0.802SerTrp: 0.802 ± 0.01	2.163SerTyr: 2.163 ± 0.018	0.001SerXaa: 0.001 ± 0.0
Thr	4.215ThrAla: 4.215 ± 0.024	1.136ThrCys: 1.136 ± 0.018	3.046ThrAsp: 3.046 ± 0.018	3.71ThrGlu: 3.71 ± 0.028	1.992ThrPhe: 1.992 ± 0.017	3.536ThrGly: 3.536 ± 0.026	1.25ThrHis: 1.25 ± 0.011	3.237ThrIle: 3.237 ± 0.023	3.227ThrLys: 3.227 ± 0.025	5.252ThrLeu: 5.252 ± 0.027	1.384ThrMet: 1.384 ± 0.012	2.584ThrAsn: 2.584 ± 0.02	3.693ThrPro: 3.693 ± 0.03	2.237ThrGln: 2.237 ± 0.019	3.036ThrArg: 3.036 ± 0.019	5.531ThrSer: 5.531 ± 0.033	4.682ThrThr: 4.682 ± 0.048	4.019ThrVal: 4.019 ± 0.021	0.615ThrTrp: 0.615 ± 0.006	1.613ThrTyr: 1.613 ± 0.015	0.001ThrXaa: 0.001 ± 0.0
Val	4.543ValAla: 4.543 ± 0.029	1.285ValCys: 1.285 ± 0.018	3.496ValAsp: 3.496 ± 0.023	4.234ValGlu: 4.234 ± 0.03	2.046ValPhe: 2.046 ± 0.019	3.202ValGly: 3.202 ± 0.02	1.474ValHis: 1.474 ± 0.013	3.242ValIle: 3.242 ± 0.017	3.701ValLys: 3.701 ± 0.03	5.399ValLeu: 5.399 ± 0.029	1.375ValMet: 1.375 ± 0.012	2.832ValAsn: 2.832 ± 0.018	3.352ValPro: 3.352 ± 0.019	2.669ValGln: 2.669 ± 0.021	3.389ValArg: 3.389 ± 0.02	4.949ValSer: 4.949 ± 0.027	4.087ValThr: 4.087 ± 0.026	4.085ValVal: 4.085 ± 0.023	0.625ValTrp: 0.625 ± 0.008	1.735ValTyr: 1.735 ± 0.015	0.001ValXaa: 0.001 ± 0.0
Trp	0.557TrpAla: 0.557 ± 0.007	0.219TrpCys: 0.219 ± 0.004	0.574TrpAsp: 0.574 ± 0.008	0.622TrpGlu: 0.622 ± 0.007	0.387TrpPhe: 0.387 ± 0.006	0.483TrpGly: 0.483 ± 0.008	0.267TrpHis: 0.267 ± 0.005	0.569TrpIle: 0.569 ± 0.009	0.647TrpLys: 0.647 ± 0.009	1.076TrpLeu: 1.076 ± 0.013	0.275TrpMet: 0.275 ± 0.006	0.527TrpAsn: 0.527 ± 0.008	0.406TrpPro: 0.406 ± 0.007	0.474TrpGln: 0.474 ± 0.007	0.712TrpArg: 0.712 ± 0.008	0.807TrpSer: 0.807 ± 0.009	0.576TrpThr: 0.576 ± 0.008	0.54TrpVal: 0.54 ± 0.007	0.18TrpTrp: 0.18 ± 0.005	0.345TrpTyr: 0.345 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.701TyrAla: 1.701 ± 0.014	0.672TyrCys: 0.672 ± 0.01	1.668TyrAsp: 1.668 ± 0.016	1.822TyrGlu: 1.822 ± 0.016	1.182TyrPhe: 1.182 ± 0.015	1.792TyrGly: 1.792 ± 0.019	0.864TyrHis: 0.864 ± 0.008	1.528TyrIle: 1.528 ± 0.013	1.671TyrLys: 1.671 ± 0.013	2.598TyrLeu: 2.598 ± 0.022	0.714TyrMet: 0.714 ± 0.008	1.463TyrAsn: 1.463 ± 0.014	1.356TyrPro: 1.356 ± 0.018	1.196TyrGln: 1.196 ± 0.012	1.75TyrArg: 1.75 ± 0.013	2.174TyrSer: 2.174 ± 0.02	1.658TyrThr: 1.658 ± 0.013	1.866TyrVal: 1.866 ± 0.017	0.344TyrTrp: 0.344 ± 0.007	1.09TyrTyr: 1.09 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.002XaaXaa: 0.002 ± 0.001

Statistics based on 17673 proteins (12470770 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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