Amino acid dipepetide frequency for Eastern grey kangaroopox virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.186AlaAla: 7.186 ± 0.536
1.383AlaCys: 1.383 ± 0.188
3.739AlaAsp: 3.739 ± 0.275
4.771AlaGlu: 4.771 ± 0.352
2.532AlaPhe: 2.532 ± 0.288
4.576AlaGly: 4.576 ± 0.657
1.363AlaHis: 1.363 ± 0.127
3.252AlaIle: 3.252 ± 0.26
2.045AlaLys: 2.045 ± 0.227
6.329AlaLeu: 6.329 ± 0.473
1.714AlaMet: 1.714 ± 0.186
2.532AlaAsn: 2.532 ± 0.273
2.999AlaPro: 2.999 ± 0.324
1.402AlaGln: 1.402 ± 0.174
5.336AlaArg: 5.336 ± 0.39
5.842AlaSer: 5.842 ± 0.501
3.603AlaThr: 3.603 ± 0.272
6.037AlaVal: 6.037 ± 0.411
0.312AlaTrp: 0.312 ± 0.072
2.473AlaTyr: 2.473 ± 0.188
0.0AlaXaa: 0.0 ± 0.0
Cys
1.246CysAla: 1.246 ± 0.155
0.74CysCys: 0.74 ± 0.117
1.052CysAsp: 1.052 ± 0.148
1.305CysGlu: 1.305 ± 0.173
0.954CysPhe: 0.954 ± 0.138
1.402CysGly: 1.402 ± 0.172
0.604CysHis: 0.604 ± 0.107
1.052CysIle: 1.052 ± 0.163
0.701CysLys: 0.701 ± 0.145
2.434CysLeu: 2.434 ± 0.226
0.428CysMet: 0.428 ± 0.101
0.759CysAsn: 0.759 ± 0.114
0.974CysPro: 0.974 ± 0.22
0.565CysGln: 0.565 ± 0.118
1.753CysArg: 1.753 ± 0.203
1.811CysSer: 1.811 ± 0.206
1.11CysThr: 1.11 ± 0.167
1.714CysVal: 1.714 ± 0.18
0.175CysTrp: 0.175 ± 0.063
1.285CysTyr: 1.285 ± 0.22
0.0CysXaa: 0.0 ± 0.0
Asp
4.557AspAla: 4.557 ± 0.285
0.721AspCys: 0.721 ± 0.125
2.999AspAsp: 2.999 ± 0.269
3.836AspGlu: 3.836 ± 0.268
2.921AspPhe: 2.921 ± 0.303
3.233AspGly: 3.233 ± 0.291
0.857AspHis: 0.857 ± 0.146
3.525AspIle: 3.525 ± 0.311
2.298AspLys: 2.298 ± 0.227
5.608AspLeu: 5.608 ± 0.3
1.266AspMet: 1.266 ± 0.14
2.025AspAsn: 2.025 ± 0.178
2.434AspPro: 2.434 ± 0.213
1.091AspGln: 1.091 ± 0.15
3.7AspArg: 3.7 ± 0.292
4.265AspSer: 4.265 ± 0.296
3.408AspThr: 3.408 ± 0.259
4.966AspVal: 4.966 ± 0.321
0.351AspTrp: 0.351 ± 0.097
2.181AspTyr: 2.181 ± 0.205
0.0AspXaa: 0.0 ± 0.0
Glu
3.953GluAla: 3.953 ± 0.252
1.071GluCys: 1.071 ± 0.15
4.382GluAsp: 4.382 ± 0.32
5.258GluGlu: 5.258 ± 0.386
2.415GluPhe: 2.415 ± 0.215
2.726GluGly: 2.726 ± 0.253
1.889GluHis: 1.889 ± 0.223
3.778GluIle: 3.778 ± 0.267
2.843GluLys: 2.843 ± 0.281
6.095GluLeu: 6.095 ± 0.329
1.714GluMet: 1.714 ± 0.154
2.181GluAsn: 2.181 ± 0.227
3.077GluPro: 3.077 ± 0.317
1.422GluGln: 1.422 ± 0.144
4.557GluArg: 4.557 ± 0.351
4.518GluSer: 4.518 ± 0.277
3.797GluThr: 3.797 ± 0.334
4.635GluVal: 4.635 ± 0.307
0.389GluTrp: 0.389 ± 0.098
2.979GluTyr: 2.979 ± 0.226
0.0GluXaa: 0.0 ± 0.0
Phe
2.921PheAla: 2.921 ± 0.243
1.227PheCys: 1.227 ± 0.164
2.493PheAsp: 2.493 ± 0.214
2.726PheGlu: 2.726 ± 0.259
1.908PhePhe: 1.908 ± 0.233
2.162PheGly: 2.162 ± 0.22
0.993PheHis: 0.993 ± 0.129
2.376PheIle: 2.376 ± 0.217
1.597PheLys: 1.597 ± 0.162
5.024PheLeu: 5.024 ± 0.367
1.11PheMet: 1.11 ± 0.145
1.928PheAsn: 1.928 ± 0.206
1.986PhePro: 1.986 ± 0.191
1.032PheGln: 1.032 ± 0.158
2.648PheArg: 2.648 ± 0.277
4.596PheSer: 4.596 ± 0.297
2.045PheThr: 2.045 ± 0.244
3.817PheVal: 3.817 ± 0.288
0.234PheTrp: 0.234 ± 0.071
1.928PheTyr: 1.928 ± 0.208
0.0PheXaa: 0.0 ± 0.0
Gly
4.265GlyAla: 4.265 ± 0.688
1.149GlyCys: 1.149 ± 0.158
3.369GlyAsp: 3.369 ± 0.248
3.544GlyGlu: 3.544 ± 0.309
1.831GlyPhe: 1.831 ± 0.182
3.817GlyGly: 3.817 ± 0.578
1.013GlyHis: 1.013 ± 0.136
2.979GlyIle: 2.979 ± 0.291
2.648GlyLys: 2.648 ± 0.268
3.856GlyLeu: 3.856 ± 0.398
1.091GlyMet: 1.091 ± 0.173
2.317GlyAsn: 2.317 ± 0.248
1.772GlyPro: 1.772 ± 0.185
0.896GlyGln: 0.896 ± 0.122
4.323GlyArg: 4.323 ± 0.246
4.576GlySer: 4.576 ± 0.462
4.265GlyThr: 4.265 ± 0.287
3.661GlyVal: 3.661 ± 0.294
0.389GlyTrp: 0.389 ± 0.073
2.415GlyTyr: 2.415 ± 0.211
0.0GlyXaa: 0.0 ± 0.0
His
1.675HisAla: 1.675 ± 0.187
0.545HisCys: 0.545 ± 0.09
1.207HisAsp: 1.207 ± 0.177
1.129HisGlu: 1.129 ± 0.153
0.721HisPhe: 0.721 ± 0.127
1.402HisGly: 1.402 ± 0.182
0.818HisHis: 0.818 ± 0.157
1.032HisIle: 1.032 ± 0.149
0.721HisLys: 0.721 ± 0.132
2.532HisLeu: 2.532 ± 0.267
0.798HisMet: 0.798 ± 0.12
0.604HisAsn: 0.604 ± 0.125
1.129HisPro: 1.129 ± 0.167
0.292HisGln: 0.292 ± 0.063
2.064HisArg: 2.064 ± 0.213
1.441HisSer: 1.441 ± 0.186
0.974HisThr: 0.974 ± 0.121
2.473HisVal: 2.473 ± 0.239
0.156HisTrp: 0.156 ± 0.055
0.837HisTyr: 0.837 ± 0.143
0.0HisXaa: 0.0 ± 0.0
Ile
3.291IleAla: 3.291 ± 0.255
1.188IleCys: 1.188 ± 0.16
3.135IleAsp: 3.135 ± 0.253
3.116IleGlu: 3.116 ± 0.253
3.038IlePhe: 3.038 ± 0.28
2.376IleGly: 2.376 ± 0.2
1.071IleHis: 1.071 ± 0.127
3.077IleIle: 3.077 ± 0.295
2.239IleLys: 2.239 ± 0.313
5.102IleLeu: 5.102 ± 0.387
1.091IleMet: 1.091 ± 0.176
3.174IleAsn: 3.174 ± 0.392
2.454IlePro: 2.454 ± 0.208
0.993IleGln: 0.993 ± 0.145
3.836IleArg: 3.836 ± 0.254
5.258IleSer: 5.258 ± 0.367
2.824IleThr: 2.824 ± 0.229
3.739IleVal: 3.739 ± 0.248
0.37IleTrp: 0.37 ± 0.094
2.512IleTyr: 2.512 ± 0.248
0.0IleXaa: 0.0 ± 0.0
Lys
1.636LysAla: 1.636 ± 0.195
0.759LysCys: 0.759 ± 0.106
1.889LysAsp: 1.889 ± 0.22
1.733LysGlu: 1.733 ± 0.179
2.2LysPhe: 2.2 ± 0.253
1.285LysGly: 1.285 ± 0.155
1.422LysHis: 1.422 ± 0.173
3.077LysIle: 3.077 ± 0.382
2.863LysLys: 2.863 ± 0.321
4.907LysLeu: 4.907 ± 0.251
1.168LysMet: 1.168 ± 0.145
2.045LysAsn: 2.045 ± 0.226
1.383LysPro: 1.383 ± 0.187
0.974LysGln: 0.974 ± 0.159
2.57LysArg: 2.57 ± 0.238
2.629LysSer: 2.629 ± 0.256
2.434LysThr: 2.434 ± 0.281
3.31LysVal: 3.31 ± 0.384
0.156LysTrp: 0.156 ± 0.049
1.675LysTyr: 1.675 ± 0.248
0.0LysXaa: 0.0 ± 0.0
Leu
6.933LeuAla: 6.933 ± 0.424
2.259LeuCys: 2.259 ± 0.264
5.258LeuAsp: 5.258 ± 0.355
6.601LeuGlu: 6.601 ± 0.363
4.557LeuPhe: 4.557 ± 0.358
5.394LeuGly: 5.394 ± 0.434
2.025LeuHis: 2.025 ± 0.224
4.713LeuIle: 4.713 ± 0.298
3.622LeuLys: 3.622 ± 0.284
10.34LeuLeu: 10.34 ± 0.563
2.123LeuMet: 2.123 ± 0.195
3.564LeuAsn: 3.564 ± 0.268
4.148LeuPro: 4.148 ± 0.297
2.045LeuGln: 2.045 ± 0.262
7.575LeuArg: 7.575 ± 0.548
9.25LeuSer: 9.25 ± 0.451
5.005LeuThr: 5.005 ± 0.363
7.809LeuVal: 7.809 ± 0.451
0.37LeuTrp: 0.37 ± 0.085
4.031LeuTyr: 4.031 ± 0.272
0.0LeuXaa: 0.0 ± 0.0
Met
1.694MetAla: 1.694 ± 0.183
0.312MetCys: 0.312 ± 0.08
1.441MetAsp: 1.441 ± 0.177
1.733MetGlu: 1.733 ± 0.179
1.344MetPhe: 1.344 ± 0.146
0.876MetGly: 0.876 ± 0.124
0.448MetHis: 0.448 ± 0.088
1.461MetIle: 1.461 ± 0.189
0.915MetLys: 0.915 ± 0.138
2.707MetLeu: 2.707 ± 0.3
0.565MetMet: 0.565 ± 0.089
1.11MetAsn: 1.11 ± 0.133
1.091MetPro: 1.091 ± 0.151
0.701MetGln: 0.701 ± 0.127
1.967MetArg: 1.967 ± 0.184
1.831MetSer: 1.831 ± 0.203
1.266MetThr: 1.266 ± 0.149
2.064MetVal: 2.064 ± 0.241
0.175MetTrp: 0.175 ± 0.053
0.837MetTyr: 0.837 ± 0.121
0.0MetXaa: 0.0 ± 0.0
Asn
2.239AsnAla: 2.239 ± 0.248
0.779AsnCys: 0.779 ± 0.155
1.85AsnAsp: 1.85 ± 0.212
2.239AsnGlu: 2.239 ± 0.221
1.772AsnPhe: 1.772 ± 0.19
2.123AsnGly: 2.123 ± 0.223
1.11AsnHis: 1.11 ± 0.151
2.785AsnIle: 2.785 ± 0.34
1.792AsnLys: 1.792 ± 0.244
3.797AsnLeu: 3.797 ± 0.289
1.091AsnMet: 1.091 ± 0.15
2.278AsnAsn: 2.278 ± 0.297
1.792AsnPro: 1.792 ± 0.174
0.701AsnGln: 0.701 ± 0.142
2.921AsnArg: 2.921 ± 0.216
3.116AsnSer: 3.116 ± 0.237
2.084AsnThr: 2.084 ± 0.213
3.661AsnVal: 3.661 ± 0.228
0.234AsnTrp: 0.234 ± 0.058
1.831AsnTyr: 1.831 ± 0.244
0.0AsnXaa: 0.0 ± 0.0
Pro
3.447ProAla: 3.447 ± 0.392
1.266ProCys: 1.266 ± 0.235
2.687ProAsp: 2.687 ± 0.22
3.661ProGlu: 3.661 ± 0.311
1.714ProPhe: 1.714 ± 0.184
3.018ProGly: 3.018 ± 0.298
0.682ProHis: 0.682 ± 0.136
1.636ProIle: 1.636 ± 0.171
1.441ProLys: 1.441 ± 0.155
3.758ProLeu: 3.758 ± 0.288
1.013ProMet: 1.013 ± 0.136
1.188ProAsn: 1.188 ± 0.179
3.408ProPro: 3.408 ± 0.502
1.129ProGln: 1.129 ± 0.166
3.661ProArg: 3.661 ± 0.323
3.739ProSer: 3.739 ± 0.377
2.045ProThr: 2.045 ± 0.254
4.012ProVal: 4.012 ± 0.331
0.312ProTrp: 0.312 ± 0.077
1.577ProTyr: 1.577 ± 0.191
0.0ProXaa: 0.0 ± 0.0
Gln
1.227GlnAla: 1.227 ± 0.14
0.312GlnCys: 0.312 ± 0.086
1.071GlnAsp: 1.071 ± 0.153
1.577GlnGlu: 1.577 ± 0.179
0.701GlnPhe: 0.701 ± 0.13
0.954GlnGly: 0.954 ± 0.146
0.487GlnHis: 0.487 ± 0.092
0.915GlnIle: 0.915 ± 0.138
1.207GlnLys: 1.207 ± 0.186
2.415GlnLeu: 2.415 ± 0.222
0.682GlnMet: 0.682 ± 0.105
0.74GlnAsn: 0.74 ± 0.126
1.149GlnPro: 1.149 ± 0.201
0.74GlnGln: 0.74 ± 0.13
1.285GlnArg: 1.285 ± 0.151
1.227GlnSer: 1.227 ± 0.133
1.071GlnThr: 1.071 ± 0.14
1.499GlnVal: 1.499 ± 0.182
0.117GlnTrp: 0.117 ± 0.048
0.818GlnTyr: 0.818 ± 0.115
0.0GlnXaa: 0.0 ± 0.0
Arg
4.557ArgAla: 4.557 ± 0.4
1.947ArgCys: 1.947 ± 0.226
3.836ArgAsp: 3.836 ± 0.261
4.518ArgGlu: 4.518 ± 0.344
3.544ArgPhe: 3.544 ± 0.317
3.622ArgGly: 3.622 ± 0.23
1.655ArgHis: 1.655 ± 0.192
3.719ArgIle: 3.719 ± 0.224
3.642ArgLys: 3.642 ± 0.291
6.504ArgLeu: 6.504 ± 0.438
1.986ArgMet: 1.986 ± 0.23
3.252ArgAsn: 3.252 ± 0.315
3.213ArgPro: 3.213 ± 0.272
1.48ArgGln: 1.48 ± 0.213
6.816ArgArg: 6.816 ± 0.469
6.348ArgSer: 6.348 ± 0.407
4.42ArgThr: 4.42 ± 0.407
5.667ArgVal: 5.667 ± 0.317
0.74ArgTrp: 0.74 ± 0.125
4.031ArgTyr: 4.031 ± 0.295
0.0ArgXaa: 0.0 ± 0.0
Ser
6.426SerAla: 6.426 ± 0.414
1.792SerCys: 1.792 ± 0.213
4.674SerAsp: 4.674 ± 0.332
5.608SerGlu: 5.608 ± 0.303
3.836SerPhe: 3.836 ± 0.298
5.18SerGly: 5.18 ± 0.376
1.636SerHis: 1.636 ± 0.193
4.654SerIle: 4.654 ± 0.358
3.525SerLys: 3.525 ± 0.3
7.731SerLeu: 7.731 ± 0.467
1.753SerMet: 1.753 ± 0.196
2.707SerAsn: 2.707 ± 0.238
3.564SerPro: 3.564 ± 0.341
1.422SerGln: 1.422 ± 0.16
6.874SerArg: 6.874 ± 0.477
8.568SerSer: 8.568 ± 0.862
4.226SerThr: 4.226 ± 0.327
7.419SerVal: 7.419 ± 0.384
0.584SerTrp: 0.584 ± 0.117
3.252SerTyr: 3.252 ± 0.319
0.0SerXaa: 0.0 ± 0.0
Thr
3.895ThrAla: 3.895 ± 0.297
1.227ThrCys: 1.227 ± 0.144
3.31ThrAsp: 3.31 ± 0.262
3.856ThrGlu: 3.856 ± 0.262
2.493ThrPhe: 2.493 ± 0.245
3.174ThrGly: 3.174 ± 0.276
1.168ThrHis: 1.168 ± 0.14
3.038ThrIle: 3.038 ± 0.221
1.675ThrLys: 1.675 ± 0.224
4.849ThrLeu: 4.849 ± 0.288
1.422ThrMet: 1.422 ± 0.175
1.792ThrAsn: 1.792 ± 0.182
2.298ThrPro: 2.298 ± 0.276
1.091ThrGln: 1.091 ± 0.146
3.875ThrArg: 3.875 ± 0.277
4.343ThrSer: 4.343 ± 0.282
2.94ThrThr: 2.94 ± 0.281
4.79ThrVal: 4.79 ± 0.297
0.389ThrTrp: 0.389 ± 0.069
2.337ThrTyr: 2.337 ± 0.222
0.0ThrXaa: 0.0 ± 0.0
Val
5.394ValAla: 5.394 ± 0.323
2.025ValCys: 2.025 ± 0.174
4.907ValAsp: 4.907 ± 0.295
3.934ValGlu: 3.934 ± 0.293
3.719ValPhe: 3.719 ± 0.258
4.479ValGly: 4.479 ± 0.574
1.831ValHis: 1.831 ± 0.195
4.401ValIle: 4.401 ± 0.336
2.785ValLys: 2.785 ± 0.358
7.692ValLeu: 7.692 ± 0.409
2.123ValMet: 2.123 ± 0.188
3.895ValAsn: 3.895 ± 0.332
4.674ValPro: 4.674 ± 0.373
1.422ValGln: 1.422 ± 0.183
6.037ValArg: 6.037 ± 0.398
8.023ValSer: 8.023 ± 0.512
4.206ValThr: 4.206 ± 0.305
5.725ValVal: 5.725 ± 0.343
0.351ValTrp: 0.351 ± 0.076
3.739ValTyr: 3.739 ± 0.274
0.0ValXaa: 0.0 ± 0.0
Trp
0.273TrpAla: 0.273 ± 0.072
0.214TrpCys: 0.214 ± 0.073
0.273TrpAsp: 0.273 ± 0.083
0.389TrpGlu: 0.389 ± 0.1
0.351TrpPhe: 0.351 ± 0.081
0.234TrpGly: 0.234 ± 0.072
0.058TrpHis: 0.058 ± 0.031
0.331TrpIle: 0.331 ± 0.067
0.214TrpLys: 0.214 ± 0.058
0.584TrpLeu: 0.584 ± 0.123
0.253TrpMet: 0.253 ± 0.069
0.253TrpAsn: 0.253 ± 0.081
0.312TrpPro: 0.312 ± 0.081
0.117TrpGln: 0.117 ± 0.045
0.467TrpArg: 0.467 ± 0.088
0.487TrpSer: 0.487 ± 0.098
0.389TrpThr: 0.389 ± 0.093
0.584TrpVal: 0.584 ± 0.117
0.019TrpTrp: 0.019 ± 0.02
0.292TrpTyr: 0.292 ± 0.076
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.609TyrAla: 2.609 ± 0.222
1.149TyrCys: 1.149 ± 0.211
2.668TyrAsp: 2.668 ± 0.244
2.142TyrGlu: 2.142 ± 0.183
2.2TyrPhe: 2.2 ± 0.257
2.162TyrGly: 2.162 ± 0.21
1.422TyrHis: 1.422 ± 0.15
2.084TyrIle: 2.084 ± 0.258
1.344TyrLys: 1.344 ± 0.178
5.355TyrLeu: 5.355 ± 0.403
1.129TyrMet: 1.129 ± 0.15
1.85TyrAsn: 1.85 ± 0.258
1.538TyrPro: 1.538 ± 0.199
0.682TyrGln: 0.682 ± 0.126
3.233TyrArg: 3.233 ± 0.311
3.564TyrSer: 3.564 ± 0.256
1.85TyrThr: 1.85 ± 0.18
3.778TyrVal: 3.778 ± 0.293
0.273TyrTrp: 0.273 ± 0.076
1.811TyrTyr: 1.811 ± 0.219
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 162 proteins (51353 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski