Amino acid dipepetide frequency for Changjiang tombus-like virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.133AlaAla: 12.133 ± 5.821
3.033AlaCys: 3.033 ± 1.78
3.033AlaAsp: 3.033 ± 1.232
4.044AlaGlu: 4.044 ± 1.856
2.022AlaPhe: 2.022 ± 1.382
9.1AlaGly: 9.1 ± 3.39
2.022AlaHis: 2.022 ± 0.626
6.067AlaIle: 6.067 ± 3.338
3.033AlaLys: 3.033 ± 1.232
4.044AlaLeu: 4.044 ± 1.252
8.089AlaMet: 8.089 ± 2.677
4.044AlaAsn: 4.044 ± 0.811
1.011AlaPro: 1.011 ± 0.691
1.011AlaGln: 1.011 ± 0.778
6.067AlaArg: 6.067 ± 1.36
5.056AlaSer: 5.056 ± 1.792
12.133AlaThr: 12.133 ± 2.434
8.089AlaVal: 8.089 ± 1.623
1.011AlaTrp: 1.011 ± 0.989
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.011CysAla: 1.011 ± 0.691
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.011CysGlu: 1.011 ± 0.691
2.022CysPhe: 2.022 ± 1.382
0.0CysGly: 0.0 ± 0.0
1.011CysHis: 1.011 ± 0.691
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
3.033CysLeu: 3.033 ± 1.232
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.011CysPro: 1.011 ± 0.989
2.022CysGln: 2.022 ± 0.919
3.033CysArg: 3.033 ± 2.073
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
6.067CysVal: 6.067 ± 2.105
0.0CysTrp: 0.0 ± 0.0
2.022CysTyr: 2.022 ± 0.626
0.0CysXaa: 0.0 ± 0.0
Asp
5.056AspAla: 5.056 ± 1.604
1.011AspCys: 1.011 ± 0.691
1.011AspAsp: 1.011 ± 0.691
2.022AspGlu: 2.022 ± 0.626
2.022AspPhe: 2.022 ± 1.382
3.033AspGly: 3.033 ± 1.814
0.0AspHis: 0.0 ± 0.0
2.022AspIle: 2.022 ± 0.626
1.011AspLys: 1.011 ± 0.691
7.078AspLeu: 7.078 ± 1.811
1.011AspMet: 1.011 ± 0.691
0.0AspAsn: 0.0 ± 0.0
5.056AspPro: 5.056 ± 1.792
3.033AspGln: 3.033 ± 2.073
3.033AspArg: 3.033 ± 2.967
2.022AspSer: 2.022 ± 0.919
3.033AspThr: 3.033 ± 0.382
6.067AspVal: 6.067 ± 3.559
0.0AspTrp: 0.0 ± 0.0
2.022AspTyr: 2.022 ± 0.985
0.0AspXaa: 0.0 ± 0.0
Glu
5.056GluAla: 5.056 ± 3.699
0.0GluCys: 0.0 ± 0.0
2.022GluAsp: 2.022 ± 0.919
3.033GluGlu: 3.033 ± 1.814
1.011GluPhe: 1.011 ± 0.778
1.011GluGly: 1.011 ± 0.989
2.022GluHis: 2.022 ± 0.919
5.056GluIle: 5.056 ± 1.604
4.044GluLys: 4.044 ± 1.856
1.011GluLeu: 1.011 ± 0.691
4.044GluMet: 4.044 ± 1.362
1.011GluAsn: 1.011 ± 0.691
2.022GluPro: 2.022 ± 1.382
3.033GluGln: 3.033 ± 1.065
2.022GluArg: 2.022 ± 0.919
4.044GluSer: 4.044 ± 2.765
0.0GluThr: 0.0 ± 0.0
4.044GluVal: 4.044 ± 1.856
2.022GluTrp: 2.022 ± 0.626
1.011GluTyr: 1.011 ± 0.989
0.0GluXaa: 0.0 ± 0.0
Phe
3.033PheAla: 3.033 ± 0.382
2.022PheCys: 2.022 ± 0.919
3.033PheAsp: 3.033 ± 2.073
2.022PheGlu: 2.022 ± 0.626
1.011PhePhe: 1.011 ± 0.691
4.044PheGly: 4.044 ± 0.811
0.0PheHis: 0.0 ± 0.0
1.011PheIle: 1.011 ± 0.778
1.011PheLys: 1.011 ± 0.691
3.033PheLeu: 3.033 ± 1.78
3.033PheMet: 3.033 ± 1.232
1.011PheAsn: 1.011 ± 0.778
1.011PhePro: 1.011 ± 0.691
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
3.033PheSer: 3.033 ± 0.382
3.033PheThr: 3.033 ± 1.474
1.011PheVal: 1.011 ± 0.691
1.011PheTrp: 1.011 ± 0.778
1.011PheTyr: 1.011 ± 0.691
0.0PheXaa: 0.0 ± 0.0
Gly
3.033GlyAla: 3.033 ± 1.474
0.0GlyCys: 0.0 ± 0.0
7.078GlyAsp: 7.078 ± 0.607
1.011GlyGlu: 1.011 ± 0.989
3.033GlyPhe: 3.033 ± 1.065
11.122GlyGly: 11.122 ± 1.361
1.011GlyHis: 1.011 ± 0.691
4.044GlyIle: 4.044 ± 0.526
6.067GlyLys: 6.067 ± 1.845
5.056GlyLeu: 5.056 ± 0.313
6.067GlyMet: 6.067 ± 0.703
7.078GlyAsn: 7.078 ± 1.836
4.044GlyPro: 4.044 ± 1.362
1.011GlyGln: 1.011 ± 0.778
9.1GlyArg: 9.1 ± 1.534
3.033GlySer: 3.033 ± 1.232
7.078GlyThr: 7.078 ± 2.277
7.078GlyVal: 7.078 ± 3.183
0.0GlyTrp: 0.0 ± 0.0
5.056GlyTyr: 5.056 ± 2.72
0.0GlyXaa: 0.0 ± 0.0
His
2.022HisAla: 2.022 ± 1.382
0.0HisCys: 0.0 ± 0.0
1.011HisAsp: 1.011 ± 0.778
1.011HisGlu: 1.011 ± 0.778
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.011HisLys: 1.011 ± 0.989
1.011HisLeu: 1.011 ± 0.989
0.0HisMet: 0.0 ± 0.0
1.011HisAsn: 1.011 ± 0.989
2.022HisPro: 2.022 ± 1.382
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
4.044HisSer: 4.044 ± 1.683
1.011HisThr: 1.011 ± 0.691
1.011HisVal: 1.011 ± 0.691
1.011HisTrp: 1.011 ± 0.691
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.033IleAla: 3.033 ± 1.232
2.022IleCys: 2.022 ± 1.382
4.044IleAsp: 4.044 ± 0.526
3.033IleGlu: 3.033 ± 1.291
0.0IlePhe: 0.0 ± 0.0
6.067IleGly: 6.067 ± 3.486
2.022IleHis: 2.022 ± 0.919
0.0IleIle: 0.0 ± 0.0
3.033IleLys: 3.033 ± 1.232
2.022IleLeu: 2.022 ± 1.382
0.0IleMet: 0.0 ± 0.0
2.022IleAsn: 2.022 ± 0.985
0.0IlePro: 0.0 ± 0.0
2.022IleGln: 2.022 ± 0.919
1.011IleArg: 1.011 ± 0.989
1.011IleSer: 1.011 ± 0.778
3.033IleThr: 3.033 ± 1.065
0.0IleVal: 0.0 ± 0.0
2.022IleTrp: 2.022 ± 1.382
2.022IleTyr: 2.022 ± 0.626
0.0IleXaa: 0.0 ± 0.0
Lys
6.067LysAla: 6.067 ± 1.693
2.022LysCys: 2.022 ± 1.382
2.022LysAsp: 2.022 ± 0.919
1.011LysGlu: 1.011 ± 0.691
0.0LysPhe: 0.0 ± 0.0
4.044LysGly: 4.044 ± 1.252
0.0LysHis: 0.0 ± 0.0
3.033LysIle: 3.033 ± 1.065
1.011LysLys: 1.011 ± 0.778
5.056LysLeu: 5.056 ± 2.654
1.011LysMet: 1.011 ± 0.691
3.033LysAsn: 3.033 ± 1.232
2.022LysPro: 2.022 ± 1.382
0.0LysGln: 0.0 ± 0.0
4.044LysArg: 4.044 ± 0.526
6.067LysSer: 6.067 ± 0.764
2.022LysThr: 2.022 ± 0.985
3.033LysVal: 3.033 ± 1.78
2.022LysTrp: 2.022 ± 0.626
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.1LeuAla: 9.1 ± 1.674
3.033LeuCys: 3.033 ± 0.382
4.044LeuAsp: 4.044 ± 1.838
9.1LeuGlu: 9.1 ± 5.163
2.022LeuPhe: 2.022 ± 0.985
8.089LeuGly: 8.089 ± 3.402
0.0LeuHis: 0.0 ± 0.0
3.033LeuIle: 3.033 ± 1.232
7.078LeuLys: 7.078 ± 1.358
6.067LeuLeu: 6.067 ± 1.845
3.033LeuMet: 3.033 ± 1.291
3.033LeuAsn: 3.033 ± 0.382
4.044LeuPro: 4.044 ± 0.811
0.0LeuGln: 0.0 ± 0.0
4.044LeuArg: 4.044 ± 1.838
5.056LeuSer: 5.056 ± 1.325
4.044LeuThr: 4.044 ± 2.142
8.089LeuVal: 8.089 ± 1.483
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
6.067MetAla: 6.067 ± 1.878
2.022MetCys: 2.022 ± 1.382
1.011MetAsp: 1.011 ± 0.989
2.022MetGlu: 2.022 ± 1.978
1.011MetPhe: 1.011 ± 0.778
4.044MetGly: 4.044 ± 1.252
2.022MetHis: 2.022 ± 0.985
2.022MetIle: 2.022 ± 0.626
2.022MetLys: 2.022 ± 1.978
4.044MetLeu: 4.044 ± 1.856
3.033MetMet: 3.033 ± 1.78
1.011MetAsn: 1.011 ± 0.691
1.011MetPro: 1.011 ± 0.989
1.011MetGln: 1.011 ± 0.691
2.022MetArg: 2.022 ± 0.985
3.033MetSer: 3.033 ± 1.065
0.0MetThr: 0.0 ± 0.0
2.022MetVal: 2.022 ± 1.978
1.011MetTrp: 1.011 ± 0.691
2.022MetTyr: 2.022 ± 1.382
0.0MetXaa: 0.0 ± 0.0
Asn
2.022AsnAla: 2.022 ± 0.626
1.011AsnCys: 1.011 ± 0.691
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
1.011AsnPhe: 1.011 ± 0.778
5.056AsnGly: 5.056 ± 1.792
1.011AsnHis: 1.011 ± 0.691
2.022AsnIle: 2.022 ± 0.919
2.022AsnLys: 2.022 ± 0.985
2.022AsnLeu: 2.022 ± 0.626
0.0AsnMet: 0.0 ± 0.0
2.022AsnAsn: 2.022 ± 0.626
1.011AsnPro: 1.011 ± 0.778
0.0AsnGln: 0.0 ± 0.0
3.033AsnArg: 3.033 ± 0.382
2.022AsnSer: 2.022 ± 1.556
1.011AsnThr: 1.011 ± 0.691
2.022AsnVal: 2.022 ± 0.919
2.022AsnTrp: 2.022 ± 0.985
1.011AsnTyr: 1.011 ± 0.778
0.0AsnXaa: 0.0 ± 0.0
Pro
3.033ProAla: 3.033 ± 1.232
2.022ProCys: 2.022 ± 1.556
3.033ProAsp: 3.033 ± 1.291
2.022ProGlu: 2.022 ± 1.382
0.0ProPhe: 0.0 ± 0.0
2.022ProGly: 2.022 ± 0.985
1.011ProHis: 1.011 ± 0.691
2.022ProIle: 2.022 ± 1.556
3.033ProLys: 3.033 ± 0.382
8.089ProLeu: 8.089 ± 1.053
1.011ProMet: 1.011 ± 0.989
0.0ProAsn: 0.0 ± 0.0
2.022ProPro: 2.022 ± 0.626
0.0ProGln: 0.0 ± 0.0
7.078ProArg: 7.078 ± 1.358
3.033ProSer: 3.033 ± 2.334
3.033ProThr: 3.033 ± 1.474
4.044ProVal: 4.044 ± 1.683
2.022ProTrp: 2.022 ± 0.626
1.011ProTyr: 1.011 ± 0.778
0.0ProXaa: 0.0 ± 0.0
Gln
1.011GlnAla: 1.011 ± 0.778
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.011GlnGlu: 1.011 ± 0.691
2.022GlnPhe: 2.022 ± 0.626
1.011GlnGly: 1.011 ± 0.691
1.011GlnHis: 1.011 ± 0.691
1.011GlnIle: 1.011 ± 0.691
0.0GlnLys: 0.0 ± 0.0
1.011GlnLeu: 1.011 ± 0.691
1.011GlnMet: 1.011 ± 1.182
1.011GlnAsn: 1.011 ± 0.691
1.011GlnPro: 1.011 ± 0.691
1.011GlnGln: 1.011 ± 0.691
3.033GlnArg: 3.033 ± 0.382
2.022GlnSer: 2.022 ± 0.626
1.011GlnThr: 1.011 ± 0.778
2.022GlnVal: 2.022 ± 0.985
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.044ArgAla: 4.044 ± 1.838
1.011ArgCys: 1.011 ± 0.691
4.044ArgAsp: 4.044 ± 1.838
2.022ArgGlu: 2.022 ± 1.978
4.044ArgPhe: 4.044 ± 2.729
5.056ArgGly: 5.056 ± 1.168
2.022ArgHis: 2.022 ± 1.382
1.011ArgIle: 1.011 ± 0.691
8.089ArgLys: 8.089 ± 1.545
8.089ArgLeu: 8.089 ± 2.261
3.033ArgMet: 3.033 ± 0.382
0.0ArgAsn: 0.0 ± 0.0
3.033ArgPro: 3.033 ± 1.065
1.011ArgGln: 1.011 ± 0.691
3.033ArgArg: 3.033 ± 1.291
6.067ArgSer: 6.067 ± 2.949
4.044ArgThr: 4.044 ± 0.811
4.044ArgVal: 4.044 ± 1.362
1.011ArgTrp: 1.011 ± 0.778
3.033ArgTyr: 3.033 ± 1.065
0.0ArgXaa: 0.0 ± 0.0
Ser
9.1SerAla: 9.1 ± 1.018
1.011SerCys: 1.011 ± 0.778
2.022SerAsp: 2.022 ± 1.382
1.011SerGlu: 1.011 ± 0.691
7.078SerPhe: 7.078 ± 1.002
5.056SerGly: 5.056 ± 1.543
1.011SerHis: 1.011 ± 0.778
1.011SerIle: 1.011 ± 0.691
1.011SerLys: 1.011 ± 0.691
3.033SerLeu: 3.033 ± 1.291
1.011SerMet: 1.011 ± 0.778
0.0SerAsn: 0.0 ± 0.0
6.067SerPro: 6.067 ± 2.305
3.033SerGln: 3.033 ± 2.334
3.033SerArg: 3.033 ± 1.291
7.078SerSer: 7.078 ± 1.836
7.078SerThr: 7.078 ± 3.075
6.067SerVal: 6.067 ± 2.305
1.011SerTrp: 1.011 ± 0.691
4.044SerTyr: 4.044 ± 0.526
0.0SerXaa: 0.0 ± 0.0
Thr
4.044ThrAla: 4.044 ± 1.963
1.011ThrCys: 1.011 ± 0.989
3.033ThrAsp: 3.033 ± 1.474
2.022ThrGlu: 2.022 ± 0.985
2.022ThrPhe: 2.022 ± 0.626
8.089ThrGly: 8.089 ± 0.311
0.0ThrHis: 0.0 ± 0.0
2.022ThrIle: 2.022 ± 0.626
1.011ThrLys: 1.011 ± 0.989
4.044ThrLeu: 4.044 ± 2.142
1.011ThrMet: 1.011 ± 0.691
1.011ThrAsn: 1.011 ± 0.778
8.089ThrPro: 8.089 ± 3.011
0.0ThrGln: 0.0 ± 0.0
4.044ThrArg: 4.044 ± 0.526
6.067ThrSer: 6.067 ± 3.612
7.078ThrThr: 7.078 ± 3.075
10.111ThrVal: 10.111 ± 3.75
1.011ThrTrp: 1.011 ± 0.778
2.022ThrTyr: 2.022 ± 0.985
0.0ThrXaa: 0.0 ± 0.0
Val
11.122ValAla: 11.122 ± 4.27
0.0ValCys: 0.0 ± 0.0
7.078ValAsp: 7.078 ± 0.913
5.056ValGlu: 5.056 ± 2.35
3.033ValPhe: 3.033 ± 0.382
8.089ValGly: 8.089 ± 3.925
0.0ValHis: 0.0 ± 0.0
2.022ValIle: 2.022 ± 0.626
3.033ValLys: 3.033 ± 1.78
9.1ValLeu: 9.1 ± 1.526
2.022ValMet: 2.022 ± 0.919
1.011ValAsn: 1.011 ± 0.691
4.044ValPro: 4.044 ± 1.97
0.0ValGln: 0.0 ± 0.0
8.089ValArg: 8.089 ± 1.683
5.056ValSer: 5.056 ± 2.132
5.056ValThr: 5.056 ± 0.313
2.022ValVal: 2.022 ± 0.626
2.022ValTrp: 2.022 ± 0.626
2.022ValTyr: 2.022 ± 0.919
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.011TrpCys: 1.011 ± 0.691
2.022TrpAsp: 2.022 ± 0.919
2.022TrpGlu: 2.022 ± 0.626
0.0TrpPhe: 0.0 ± 0.0
3.033TrpGly: 3.033 ± 1.291
0.0TrpHis: 0.0 ± 0.0
1.011TrpIle: 1.011 ± 0.691
0.0TrpLys: 0.0 ± 0.0
2.022TrpLeu: 2.022 ± 0.626
1.011TrpMet: 1.011 ± 0.778
1.011TrpAsn: 1.011 ± 0.778
0.0TrpPro: 0.0 ± 0.0
1.011TrpGln: 1.011 ± 0.691
0.0TrpArg: 0.0 ± 0.0
1.011TrpSer: 1.011 ± 0.778
2.022TrpThr: 2.022 ± 1.556
2.022TrpVal: 2.022 ± 0.626
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.056TyrAla: 5.056 ± 1.173
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
3.033TyrGlu: 3.033 ± 1.291
1.011TyrPhe: 1.011 ± 0.778
3.033TyrGly: 3.033 ± 1.065
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
4.044TyrLeu: 4.044 ± 1.362
2.022TyrMet: 2.022 ± 0.672
1.011TyrAsn: 1.011 ± 0.691
1.011TyrPro: 1.011 ± 0.778
2.022TyrGln: 2.022 ± 1.382
2.022TyrArg: 2.022 ± 1.556
1.011TyrSer: 1.011 ± 0.778
2.022TyrThr: 2.022 ± 1.556
1.011TyrVal: 1.011 ± 0.778
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (990 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski