Amino acid dipepetide frequency for Beihai weivirus-like virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.094AlaAla: 16.094 ± 0.777
4.292AlaCys: 4.292 ± 0.854
5.365AlaAsp: 5.365 ± 2.028
6.438AlaGlu: 6.438 ± 3.934
4.292AlaPhe: 4.292 ± 2.623
4.292AlaGly: 4.292 ± 2.683
1.073AlaHis: 1.073 ± 0.656
1.073AlaIle: 1.073 ± 0.656
5.365AlaLys: 5.365 ± 1.51
16.094AlaLeu: 16.094 ± 6.083
3.219AlaMet: 3.219 ± 0.368
5.365AlaAsn: 5.365 ± 0.259
5.365AlaPro: 5.365 ± 2.028
2.146AlaGln: 2.146 ± 1.311
6.438AlaArg: 6.438 ± 0.397
9.657AlaSer: 9.657 ± 4.711
11.803AlaThr: 11.803 ± 3.4
4.292AlaVal: 4.292 ± 0.915
2.146AlaTrp: 2.146 ± 1.311
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
4.292CysAla: 4.292 ± 2.623
0.0CysCys: 0.0 ± 0.0
1.073CysAsp: 1.073 ± 0.656
2.146CysGlu: 2.146 ± 1.311
0.0CysPhe: 0.0 ± 0.0
1.073CysGly: 1.073 ± 0.656
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.219CysAsn: 3.219 ± 1.57
2.146CysPro: 2.146 ± 0.457
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.146CysSer: 2.146 ± 1.311
0.0CysThr: 0.0 ± 0.0
1.073CysVal: 1.073 ± 0.656
1.073CysTrp: 1.073 ± 1.113
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.292AspAla: 4.292 ± 0.915
0.0AspCys: 0.0 ± 0.0
3.219AspAsp: 3.219 ± 0.198
4.292AspGlu: 4.292 ± 2.623
3.219AspPhe: 3.219 ± 1.967
6.438AspGly: 6.438 ± 3.934
1.073AspHis: 1.073 ± 1.113
3.219AspIle: 3.219 ± 0.198
1.073AspLys: 1.073 ± 0.656
6.438AspLeu: 6.438 ± 1.372
1.073AspMet: 1.073 ± 0.656
0.0AspAsn: 0.0 ± 0.0
1.073AspPro: 1.073 ± 0.656
1.073AspGln: 1.073 ± 1.113
4.292AspArg: 4.292 ± 0.854
3.219AspSer: 3.219 ± 1.57
1.073AspThr: 1.073 ± 0.656
6.438AspVal: 6.438 ± 0.397
2.146AspTrp: 2.146 ± 2.226
1.073AspTyr: 1.073 ± 0.656
0.0AspXaa: 0.0 ± 0.0
Glu
6.438GluAla: 6.438 ± 2.165
1.073GluCys: 1.073 ± 0.656
1.073GluAsp: 1.073 ± 0.656
4.292GluGlu: 4.292 ± 2.623
2.146GluPhe: 2.146 ± 1.311
6.438GluGly: 6.438 ± 0.397
3.219GluHis: 3.219 ± 1.967
1.073GluIle: 1.073 ± 0.656
4.292GluLys: 4.292 ± 2.623
4.292GluLeu: 4.292 ± 0.854
1.073GluMet: 1.073 ± 0.656
1.073GluAsn: 1.073 ± 0.656
4.292GluPro: 4.292 ± 0.854
1.073GluGln: 1.073 ± 0.656
2.146GluArg: 2.146 ± 1.311
5.365GluSer: 5.365 ± 3.278
1.073GluThr: 1.073 ± 0.656
5.365GluVal: 5.365 ± 0.259
2.146GluTrp: 2.146 ± 1.311
3.219GluTyr: 3.219 ± 1.57
0.0GluXaa: 0.0 ± 0.0
Phe
1.073PheAla: 1.073 ± 0.656
0.0PheCys: 0.0 ± 0.0
2.146PheAsp: 2.146 ± 0.457
4.292PheGlu: 4.292 ± 0.854
1.073PhePhe: 1.073 ± 0.656
2.146PheGly: 2.146 ± 0.457
0.0PheHis: 0.0 ± 0.0
1.073PheIle: 1.073 ± 0.656
0.0PheLys: 0.0 ± 0.0
5.365PheLeu: 5.365 ± 3.278
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
2.146PhePro: 2.146 ± 1.311
2.146PheGln: 2.146 ± 2.226
3.219PheArg: 3.219 ± 1.967
1.073PheSer: 1.073 ± 0.656
4.292PheThr: 4.292 ± 0.854
2.146PheVal: 2.146 ± 0.457
0.0PheTrp: 0.0 ± 0.0
2.146PheTyr: 2.146 ± 1.311
0.0PheXaa: 0.0 ± 0.0
Gly
7.511GlyAla: 7.511 ± 1.052
0.0GlyCys: 0.0 ± 0.0
7.511GlyAsp: 7.511 ± 1.052
3.219GlyGlu: 3.219 ± 1.967
0.0GlyPhe: 0.0 ± 0.0
3.219GlyGly: 3.219 ± 1.57
2.146GlyHis: 2.146 ± 2.226
4.292GlyIle: 4.292 ± 0.915
3.219GlyLys: 3.219 ± 0.198
3.219GlyLeu: 3.219 ± 1.57
2.146GlyMet: 2.146 ± 0.457
4.292GlyAsn: 4.292 ± 0.915
1.073GlyPro: 1.073 ± 1.113
2.146GlyGln: 2.146 ± 0.457
6.438GlyArg: 6.438 ± 3.141
3.219GlySer: 3.219 ± 0.198
7.511GlyThr: 7.511 ± 0.716
6.438GlyVal: 6.438 ± 1.372
2.146GlyTrp: 2.146 ± 0.457
2.146GlyTyr: 2.146 ± 1.311
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.073HisCys: 1.073 ± 1.113
1.073HisAsp: 1.073 ± 0.656
0.0HisGlu: 0.0 ± 0.0
1.073HisPhe: 1.073 ± 0.656
2.146HisGly: 2.146 ± 1.311
1.073HisHis: 1.073 ± 1.113
1.073HisIle: 1.073 ± 1.113
1.073HisLys: 1.073 ± 0.656
2.146HisLeu: 2.146 ± 2.226
1.073HisMet: 1.073 ± 0.656
0.0HisAsn: 0.0 ± 0.0
3.219HisPro: 3.219 ± 3.339
1.073HisGln: 1.073 ± 0.656
1.073HisArg: 1.073 ± 0.656
0.0HisSer: 0.0 ± 0.0
1.073HisThr: 1.073 ± 1.113
2.146HisVal: 2.146 ± 1.311
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.365IleAla: 5.365 ± 0.259
0.0IleCys: 0.0 ± 0.0
1.073IleAsp: 1.073 ± 0.656
1.073IleGlu: 1.073 ± 0.656
1.073IlePhe: 1.073 ± 0.656
2.146IleGly: 2.146 ± 0.457
0.0IleHis: 0.0 ± 0.0
1.073IleIle: 1.073 ± 1.113
2.146IleLys: 2.146 ± 1.311
3.219IleLeu: 3.219 ± 1.967
0.0IleMet: 0.0 ± 0.0
2.146IleAsn: 2.146 ± 2.226
0.0IlePro: 0.0 ± 0.0
1.073IleGln: 1.073 ± 1.113
1.073IleArg: 1.073 ± 0.656
1.073IleSer: 1.073 ± 0.656
2.146IleThr: 2.146 ± 0.457
1.073IleVal: 1.073 ± 1.113
0.0IleTrp: 0.0 ± 0.0
2.146IleTyr: 2.146 ± 2.226
0.0IleXaa: 0.0 ± 0.0
Lys
5.365LysAla: 5.365 ± 3.278
1.073LysCys: 1.073 ± 0.656
1.073LysAsp: 1.073 ± 0.656
3.219LysGlu: 3.219 ± 0.198
3.219LysPhe: 3.219 ± 1.57
2.146LysGly: 2.146 ± 0.457
2.146LysHis: 2.146 ± 0.457
0.0LysIle: 0.0 ± 0.0
1.073LysLys: 1.073 ± 0.656
7.511LysLeu: 7.511 ± 2.821
1.073LysMet: 1.073 ± 0.656
2.146LysAsn: 2.146 ± 0.457
4.292LysPro: 4.292 ± 0.854
1.073LysGln: 1.073 ± 0.656
3.219LysArg: 3.219 ± 1.967
2.146LysSer: 2.146 ± 1.311
4.292LysThr: 4.292 ± 2.623
1.073LysVal: 1.073 ± 0.656
0.0LysTrp: 0.0 ± 0.0
1.073LysTyr: 1.073 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
12.876LeuAla: 12.876 ± 0.975
2.146LeuCys: 2.146 ± 1.311
2.146LeuAsp: 2.146 ± 0.457
3.219LeuGlu: 3.219 ± 0.198
3.219LeuPhe: 3.219 ± 1.967
4.292LeuGly: 4.292 ± 2.683
1.073LeuHis: 1.073 ± 0.656
4.292LeuIle: 4.292 ± 0.854
2.146LeuLys: 2.146 ± 1.311
7.511LeuLeu: 7.511 ± 1.052
1.073LeuMet: 1.073 ± 0.656
4.292LeuAsn: 4.292 ± 2.683
5.365LeuPro: 5.365 ± 0.259
4.292LeuGln: 4.292 ± 0.915
6.438LeuArg: 6.438 ± 0.397
8.584LeuSer: 8.584 ± 1.708
5.365LeuThr: 5.365 ± 0.259
6.438LeuVal: 6.438 ± 0.397
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.219MetAla: 3.219 ± 1.57
1.073MetCys: 1.073 ± 1.113
1.073MetAsp: 1.073 ± 1.113
1.073MetGlu: 1.073 ± 0.656
1.073MetPhe: 1.073 ± 0.656
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.073MetLys: 1.073 ± 0.656
0.0MetLeu: 0.0 ± 0.0
2.146MetMet: 2.146 ± 0.839
2.146MetAsn: 2.146 ± 0.457
1.073MetPro: 1.073 ± 0.656
0.0MetGln: 0.0 ± 0.0
3.219MetArg: 3.219 ± 1.967
2.146MetSer: 2.146 ± 1.311
2.146MetThr: 2.146 ± 0.457
3.219MetVal: 3.219 ± 1.57
0.0MetTrp: 0.0 ± 0.0
2.146MetTyr: 2.146 ± 1.311
0.0MetXaa: 0.0 ± 0.0
Asn
3.219AsnAla: 3.219 ± 0.198
0.0AsnCys: 0.0 ± 0.0
4.292AsnAsp: 4.292 ± 2.623
0.0AsnGlu: 0.0 ± 0.0
1.073AsnPhe: 1.073 ± 0.656
5.365AsnGly: 5.365 ± 3.797
1.073AsnHis: 1.073 ± 0.656
0.0AsnIle: 0.0 ± 0.0
3.219AsnLys: 3.219 ± 0.198
2.146AsnLeu: 2.146 ± 1.311
1.073AsnMet: 1.073 ± 1.113
1.073AsnAsn: 1.073 ± 1.113
3.219AsnPro: 3.219 ± 1.57
0.0AsnGln: 0.0 ± 0.0
2.146AsnArg: 2.146 ± 0.457
1.073AsnSer: 1.073 ± 1.113
6.438AsnThr: 6.438 ± 3.141
2.146AsnVal: 2.146 ± 0.457
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.292ProAla: 4.292 ± 0.915
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
4.292ProGlu: 4.292 ± 0.854
1.073ProPhe: 1.073 ± 1.113
4.292ProGly: 4.292 ± 0.854
0.0ProHis: 0.0 ± 0.0
3.219ProIle: 3.219 ± 1.57
4.292ProLys: 4.292 ± 0.854
3.219ProLeu: 3.219 ± 1.57
1.073ProMet: 1.073 ± 0.656
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
7.511ProArg: 7.511 ± 0.716
5.365ProSer: 5.365 ± 2.028
3.219ProThr: 3.219 ± 1.57
2.146ProVal: 2.146 ± 0.457
0.0ProTrp: 0.0 ± 0.0
1.073ProTyr: 1.073 ± 1.113
0.0ProXaa: 0.0 ± 0.0
Gln
4.292GlnAla: 4.292 ± 0.915
0.0GlnCys: 0.0 ± 0.0
1.073GlnAsp: 1.073 ± 0.656
1.073GlnGlu: 1.073 ± 1.113
2.146GlnPhe: 2.146 ± 2.226
2.146GlnGly: 2.146 ± 2.226
0.0GlnHis: 0.0 ± 0.0
2.146GlnIle: 2.146 ± 0.457
1.073GlnLys: 1.073 ± 0.656
1.073GlnLeu: 1.073 ± 1.113
0.0GlnMet: 0.0 ± 0.0
1.073GlnAsn: 1.073 ± 0.656
2.146GlnPro: 2.146 ± 1.311
2.146GlnGln: 2.146 ± 1.311
1.073GlnArg: 1.073 ± 1.113
1.073GlnSer: 1.073 ± 1.113
1.073GlnThr: 1.073 ± 1.113
1.073GlnVal: 1.073 ± 1.113
2.146GlnTrp: 2.146 ± 1.311
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.511ArgAla: 7.511 ± 7.791
0.0ArgCys: 0.0 ± 0.0
4.292ArgAsp: 4.292 ± 2.623
4.292ArgGlu: 4.292 ± 2.623
2.146ArgPhe: 2.146 ± 0.457
2.146ArgGly: 2.146 ± 0.457
2.146ArgHis: 2.146 ± 1.311
1.073ArgIle: 1.073 ± 0.656
4.292ArgLys: 4.292 ± 0.915
6.438ArgLeu: 6.438 ± 2.165
2.146ArgMet: 2.146 ± 0.457
2.146ArgAsn: 2.146 ± 1.311
3.219ArgPro: 3.219 ± 0.198
1.073ArgGln: 1.073 ± 1.113
5.365ArgArg: 5.365 ± 2.028
4.292ArgSer: 4.292 ± 2.683
4.292ArgThr: 4.292 ± 2.623
11.803ArgVal: 11.803 ± 1.631
2.146ArgTrp: 2.146 ± 1.311
1.073ArgTyr: 1.073 ± 0.656
0.0ArgXaa: 0.0 ± 0.0
Ser
6.438SerAla: 6.438 ± 1.372
1.073SerCys: 1.073 ± 0.656
3.219SerAsp: 3.219 ± 0.198
6.438SerGlu: 6.438 ± 2.165
2.146SerPhe: 2.146 ± 1.311
6.438SerGly: 6.438 ± 0.397
2.146SerHis: 2.146 ± 2.226
1.073SerIle: 1.073 ± 0.656
3.219SerLys: 3.219 ± 1.57
5.365SerLeu: 5.365 ± 3.278
4.292SerMet: 4.292 ± 2.623
2.146SerAsn: 2.146 ± 1.311
1.073SerPro: 1.073 ± 1.113
2.146SerGln: 2.146 ± 0.457
1.073SerArg: 1.073 ± 1.113
3.219SerSer: 3.219 ± 1.967
4.292SerThr: 4.292 ± 0.915
4.292SerVal: 4.292 ± 2.683
3.219SerTrp: 3.219 ± 0.198
2.146SerTyr: 2.146 ± 0.457
0.0SerXaa: 0.0 ± 0.0
Thr
8.584ThrAla: 8.584 ± 3.598
2.146ThrCys: 2.146 ± 1.311
4.292ThrAsp: 4.292 ± 0.854
2.146ThrGlu: 2.146 ± 0.457
2.146ThrPhe: 2.146 ± 0.457
6.438ThrGly: 6.438 ± 1.372
2.146ThrHis: 2.146 ± 2.226
1.073ThrIle: 1.073 ± 0.656
5.365ThrLys: 5.365 ± 3.278
5.365ThrLeu: 5.365 ± 0.259
1.073ThrMet: 1.073 ± 1.113
3.219ThrAsn: 3.219 ± 1.57
2.146ThrPro: 2.146 ± 0.457
1.073ThrGln: 1.073 ± 1.113
7.511ThrArg: 7.511 ± 2.485
4.292ThrSer: 4.292 ± 2.623
5.365ThrThr: 5.365 ± 0.259
8.584ThrVal: 8.584 ± 0.061
1.073ThrTrp: 1.073 ± 1.113
1.073ThrTyr: 1.073 ± 0.656
0.0ThrXaa: 0.0 ± 0.0
Val
9.657ValAla: 9.657 ± 0.595
0.0ValCys: 0.0 ± 0.0
4.292ValAsp: 4.292 ± 0.915
6.438ValGlu: 6.438 ± 0.397
3.219ValPhe: 3.219 ± 1.967
9.657ValGly: 9.657 ± 1.174
1.073ValHis: 1.073 ± 0.656
2.146ValIle: 2.146 ± 2.226
1.073ValLys: 1.073 ± 0.656
4.292ValLeu: 4.292 ± 0.915
4.292ValMet: 4.292 ± 2.683
2.146ValAsn: 2.146 ± 1.311
2.146ValPro: 2.146 ± 2.226
3.219ValGln: 3.219 ± 3.339
7.511ValArg: 7.511 ± 0.716
3.219ValSer: 3.219 ± 0.198
4.292ValThr: 4.292 ± 0.915
5.365ValVal: 5.365 ± 0.259
2.146ValTrp: 2.146 ± 1.311
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.146TrpAla: 2.146 ± 0.457
3.219TrpCys: 3.219 ± 0.198
3.219TrpAsp: 3.219 ± 3.339
1.073TrpGlu: 1.073 ± 0.656
0.0TrpPhe: 0.0 ± 0.0
1.073TrpGly: 1.073 ± 0.656
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
3.219TrpLys: 3.219 ± 1.967
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.073TrpGln: 1.073 ± 0.656
0.0TrpArg: 0.0 ± 0.0
2.146TrpSer: 2.146 ± 0.457
2.146TrpThr: 2.146 ± 1.311
1.073TrpVal: 1.073 ± 0.656
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.146TyrAla: 2.146 ± 0.457
1.073TyrCys: 1.073 ± 0.656
3.219TyrAsp: 3.219 ± 1.967
2.146TyrGlu: 2.146 ± 1.311
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
1.073TyrLeu: 1.073 ± 0.656
0.0TyrMet: 0.0 ± 0.0
1.073TyrAsn: 1.073 ± 1.113
1.073TyrPro: 1.073 ± 1.113
0.0TyrGln: 0.0 ± 0.0
2.146TyrArg: 2.146 ± 0.457
2.146TyrSer: 2.146 ± 1.311
3.219TyrThr: 3.219 ± 1.57
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (933 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski