Amino acid dipepetide frequency for Litorimonas taeanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.531AlaAla: 10.531 ± 0.164	1.027AlaCys: 1.027 ± 0.04	5.528AlaAsp: 5.528 ± 0.089	6.573AlaGlu: 6.573 ± 0.109	4.092AlaPhe: 4.092 ± 0.077	7.575AlaGly: 7.575 ± 0.113	1.836AlaHis: 1.836 ± 0.045	6.019AlaIle: 6.019 ± 0.096	5.463AlaLys: 5.463 ± 0.103	11.14AlaLeu: 11.14 ± 0.158	2.806AlaMet: 2.806 ± 0.067	3.336AlaAsn: 3.336 ± 0.072	4.336AlaPro: 4.336 ± 0.081	3.792AlaGln: 3.792 ± 0.08	5.258AlaArg: 5.258 ± 0.1	5.914AlaSer: 5.914 ± 0.116	4.782AlaThr: 4.782 ± 0.096	6.374AlaVal: 6.374 ± 0.131	1.035AlaTrp: 1.035 ± 0.037	2.715AlaTyr: 2.715 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.866CysAla: 0.866 ± 0.033	0.09CysCys: 0.09 ± 0.01	0.558CysAsp: 0.558 ± 0.028	0.482CysGlu: 0.482 ± 0.027	0.329CysPhe: 0.329 ± 0.023	0.769CysGly: 0.769 ± 0.032	0.202CysHis: 0.202 ± 0.016	0.42CysIle: 0.42 ± 0.023	0.321CysLys: 0.321 ± 0.021	0.866CysLeu: 0.866 ± 0.041	0.151CysMet: 0.151 ± 0.014	0.249CysAsn: 0.249 ± 0.017	0.446CysPro: 0.446 ± 0.026	0.288CysGln: 0.288 ± 0.018	0.425CysArg: 0.425 ± 0.022	0.545CysSer: 0.545 ± 0.026	0.455CysThr: 0.455 ± 0.024	0.655CysVal: 0.655 ± 0.029	0.08CysTrp: 0.08 ± 0.011	0.199CysTyr: 0.199 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.619AspAla: 5.619 ± 0.092	0.517AspCys: 0.517 ± 0.026	3.479AspAsp: 3.479 ± 0.069	3.908AspGlu: 3.908 ± 0.08	2.634AspPhe: 2.634 ± 0.063	4.74AspGly: 4.74 ± 0.083	1.065AspHis: 1.065 ± 0.039	4.526AspIle: 4.526 ± 0.085	3.05AspLys: 3.05 ± 0.065	5.592AspLeu: 5.592 ± 0.09	1.787AspMet: 1.787 ± 0.042	2.229AspAsn: 2.229 ± 0.062	2.743AspPro: 2.743 ± 0.064	1.588AspGln: 1.588 ± 0.045	3.14AspArg: 3.14 ± 0.067	3.068AspSer: 3.068 ± 0.065	3.232AspThr: 3.232 ± 0.067	4.418AspVal: 4.418 ± 0.091	0.917AspTrp: 0.917 ± 0.035	2.131AspTyr: 2.131 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	7.055GluAla: 7.055 ± 0.107	0.369GluCys: 0.369 ± 0.024	3.713GluAsp: 3.713 ± 0.072	3.381GluGlu: 3.381 ± 0.082	2.192GluPhe: 2.192 ± 0.054	4.483GluGly: 4.483 ± 0.069	1.094GluHis: 1.094 ± 0.038	4.107GluIle: 4.107 ± 0.078	3.466GluLys: 3.466 ± 0.082	4.957GluLeu: 4.957 ± 0.082	1.774GluMet: 1.774 ± 0.054	2.75GluAsn: 2.75 ± 0.058	2.139GluPro: 2.139 ± 0.084	2.204GluGln: 2.204 ± 0.06	3.896GluArg: 3.896 ± 0.083	3.534GluSer: 3.534 ± 0.081	4.711GluThr: 4.711 ± 0.139	3.499GluVal: 3.499 ± 0.078	0.675GluTrp: 0.675 ± 0.024	1.405GluTyr: 1.405 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.845PheAla: 3.845 ± 0.075	0.388PheCys: 0.388 ± 0.023	2.928PheAsp: 2.928 ± 0.063	2.592PheGlu: 2.592 ± 0.062	1.639PhePhe: 1.639 ± 0.054	3.713PheGly: 3.713 ± 0.078	0.71PheHis: 0.71 ± 0.032	2.569PheIle: 2.569 ± 0.073	1.945PheLys: 1.945 ± 0.051	3.539PheLeu: 3.539 ± 0.079	1.055PheMet: 1.055 ± 0.034	1.685PheAsn: 1.685 ± 0.05	1.458PhePro: 1.458 ± 0.042	1.145PheGln: 1.145 ± 0.036	1.824PheArg: 1.824 ± 0.048	2.933PheSer: 2.933 ± 0.076	2.426PheThr: 2.426 ± 0.056	2.612PheVal: 2.612 ± 0.056	0.552PheTrp: 0.552 ± 0.026	1.146PheTyr: 1.146 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	7.397GlyAla: 7.397 ± 0.124	0.707GlyCys: 0.707 ± 0.028	4.477GlyAsp: 4.477 ± 0.088	4.658GlyGlu: 4.658 ± 0.089	3.743GlyPhe: 3.743 ± 0.075	6.535GlyGly: 6.535 ± 0.131	1.662GlyHis: 1.662 ± 0.045	4.293GlyIle: 4.293 ± 0.082	3.766GlyLys: 3.766 ± 0.076	8.322GlyLeu: 8.322 ± 0.117	1.963GlyMet: 1.963 ± 0.049	2.477GlyAsn: 2.477 ± 0.073	2.876GlyPro: 2.876 ± 0.07	3.141GlyGln: 3.141 ± 0.062	4.552GlyArg: 4.552 ± 0.065	4.236GlySer: 4.236 ± 0.092	4.102GlyThr: 4.102 ± 0.087	5.666GlyVal: 5.666 ± 0.085	1.023GlyTrp: 1.023 ± 0.037	2.525GlyTyr: 2.525 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	1.747HisAla: 1.747 ± 0.051	0.221HisCys: 0.221 ± 0.016	0.999HisAsp: 0.999 ± 0.035	1.054HisGlu: 1.054 ± 0.045	0.857HisPhe: 0.857 ± 0.036	1.431HisGly: 1.431 ± 0.042	0.499HisHis: 0.499 ± 0.025	1.339HisIle: 1.339 ± 0.041	0.898HisLys: 0.898 ± 0.034	1.693HisLeu: 1.693 ± 0.051	0.504HisMet: 0.504 ± 0.022	0.718HisAsn: 0.718 ± 0.026	1.093HisPro: 1.093 ± 0.036	0.607HisGln: 0.607 ± 0.028	1.021HisArg: 1.021 ± 0.035	1.133HisSer: 1.133 ± 0.04	0.889HisThr: 0.889 ± 0.035	1.173HisVal: 1.173 ± 0.042	0.247HisTrp: 0.247 ± 0.017	0.661HisTyr: 0.661 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.613IleAla: 6.613 ± 0.115	0.637IleCys: 0.637 ± 0.03	4.176IleAsp: 4.176 ± 0.067	4.35IleGlu: 4.35 ± 0.076	2.405IlePhe: 2.405 ± 0.069	5.306IleGly: 5.306 ± 0.098	1.014IleHis: 1.014 ± 0.037	3.916IleIle: 3.916 ± 0.081	2.872IleLys: 2.872 ± 0.064	5.562IleLeu: 5.562 ± 0.094	1.424IleMet: 1.424 ± 0.047	2.264IleAsn: 2.264 ± 0.056	2.756IlePro: 2.756 ± 0.101	1.795IleGln: 1.795 ± 0.048	3.101IleArg: 3.101 ± 0.054	4.36IleSer: 4.36 ± 0.074	3.439IleThr: 3.439 ± 0.067	3.972IleVal: 3.972 ± 0.076	0.732IleTrp: 0.732 ± 0.032	1.526IleTyr: 1.526 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	5.864LysAla: 5.864 ± 0.109	0.251LysCys: 0.251 ± 0.016	3.056LysAsp: 3.056 ± 0.07	2.632LysGlu: 2.632 ± 0.063	1.716LysPhe: 1.716 ± 0.045	3.688LysGly: 3.688 ± 0.078	0.961LysHis: 0.961 ± 0.036	2.995LysIle: 2.995 ± 0.071	2.764LysLys: 2.764 ± 0.068	4.218LysLeu: 4.218 ± 0.078	1.333LysMet: 1.333 ± 0.04	1.946LysAsn: 1.946 ± 0.047	2.695LysPro: 2.695 ± 0.056	1.617LysGln: 1.617 ± 0.047	3.056LysArg: 3.056 ± 0.064	3.633LysSer: 3.633 ± 0.077	3.6LysThr: 3.6 ± 0.095	2.914LysVal: 2.914 ± 0.068	0.517LysTrp: 0.517 ± 0.026	1.14LysTyr: 1.14 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	9.417LeuAla: 9.417 ± 0.125	0.95LeuCys: 0.95 ± 0.04	5.427LeuAsp: 5.427 ± 0.094	5.721LeuGlu: 5.721 ± 0.092	3.753LeuPhe: 3.753 ± 0.076	7.386LeuGly: 7.386 ± 0.11	1.607LeuHis: 1.607 ± 0.05	5.969LeuIle: 5.969 ± 0.122	5.063LeuLys: 5.063 ± 0.089	7.858LeuLeu: 7.858 ± 0.122	2.409LeuMet: 2.409 ± 0.054	3.871LeuAsn: 3.871 ± 0.075	4.711LeuPro: 4.711 ± 0.079	2.958LeuGln: 2.958 ± 0.065	5.256LeuArg: 5.256 ± 0.09	8.066LeuSer: 8.066 ± 0.118	5.68LeuThr: 5.68 ± 0.079	5.498LeuVal: 5.498 ± 0.088	1.017LeuTrp: 1.017 ± 0.04	2.362LeuTyr: 2.362 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.932MetAla: 2.932 ± 0.062	0.181MetCys: 0.181 ± 0.014	1.386MetAsp: 1.386 ± 0.045	1.336MetGlu: 1.336 ± 0.039	0.802MetPhe: 0.802 ± 0.035	2.094MetGly: 2.094 ± 0.051	0.41MetHis: 0.41 ± 0.024	1.472MetIle: 1.472 ± 0.047	1.456MetLys: 1.456 ± 0.042	1.946MetLeu: 1.946 ± 0.052	0.768MetMet: 0.768 ± 0.032	1.038MetAsn: 1.038 ± 0.031	1.353MetPro: 1.353 ± 0.047	0.894MetGln: 0.894 ± 0.034	1.612MetArg: 1.612 ± 0.043	1.953MetSer: 1.953 ± 0.043	1.934MetThr: 1.934 ± 0.043	1.47MetVal: 1.47 ± 0.05	0.201MetTrp: 0.201 ± 0.015	0.335MetTyr: 0.335 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.797AsnAla: 3.797 ± 0.084	0.329AsnCys: 0.329 ± 0.02	2.1AsnAsp: 2.1 ± 0.05	1.868AsnGlu: 1.868 ± 0.044	1.553AsnPhe: 1.553 ± 0.052	3.067AsnGly: 3.067 ± 0.073	0.761AsnHis: 0.761 ± 0.031	2.634AsnIle: 2.634 ± 0.074	1.667AsnLys: 1.667 ± 0.043	3.624AsnLeu: 3.624 ± 0.061	0.925AsnMet: 0.925 ± 0.029	1.398AsnAsn: 1.398 ± 0.052	2.209AsnPro: 2.209 ± 0.056	1.246AsnGln: 1.246 ± 0.042	2.015AsnArg: 2.015 ± 0.053	2.265AsnSer: 2.265 ± 0.075	2.043AsnThr: 2.043 ± 0.054	2.483AsnVal: 2.483 ± 0.061	0.528AsnTrp: 0.528 ± 0.027	1.23AsnTyr: 1.23 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	3.956ProAla: 3.956 ± 0.187	0.286ProCys: 0.286 ± 0.022	3.113ProAsp: 3.113 ± 0.073	3.397ProGlu: 3.397 ± 0.095	1.909ProPhe: 1.909 ± 0.051	2.874ProGly: 2.874 ± 0.064	1.026ProHis: 1.026 ± 0.035	2.852ProIle: 2.852 ± 0.07	2.624ProLys: 2.624 ± 0.061	4.18ProLeu: 4.18 ± 0.077	1.096ProMet: 1.096 ± 0.036	1.977ProAsn: 1.977 ± 0.047	1.911ProPro: 1.911 ± 0.075	1.795ProGln: 1.795 ± 0.06	2.118ProArg: 2.118 ± 0.054	2.892ProSer: 2.892 ± 0.059	2.331ProThr: 2.331 ± 0.054	3.274ProVal: 3.274 ± 0.069	0.463ProTrp: 0.463 ± 0.025	1.4ProTyr: 1.4 ± 0.047	0.0ProXaa: 0.0 ± 0.0
Gln	3.802GlnAla: 3.802 ± 0.084	0.239GlnCys: 0.239 ± 0.018	1.971GlnAsp: 1.971 ± 0.053	1.774GlnGlu: 1.774 ± 0.085	1.363GlnPhe: 1.363 ± 0.051	2.543GlnGly: 2.543 ± 0.066	0.595GlnHis: 0.595 ± 0.025	2.268GlnIle: 2.268 ± 0.052	1.71GlnLys: 1.71 ± 0.046	2.721GlnLeu: 2.721 ± 0.057	0.926GlnMet: 0.926 ± 0.034	1.624GlnAsn: 1.624 ± 0.048	1.422GlnPro: 1.422 ± 0.048	1.026GlnGln: 1.026 ± 0.041	1.882GlnArg: 1.882 ± 0.051	2.841GlnSer: 2.841 ± 0.059	2.273GlnThr: 2.273 ± 0.067	2.018GlnVal: 2.018 ± 0.053	0.353GlnTrp: 0.353 ± 0.021	0.88GlnTyr: 0.88 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	5.23ArgAla: 5.23 ± 0.091	0.353ArgCys: 0.353 ± 0.021	3.244ArgAsp: 3.244 ± 0.066	3.341ArgGlu: 3.341 ± 0.068	2.379ArgPhe: 2.379 ± 0.057	3.633ArgGly: 3.633 ± 0.07	1.143ArgHis: 1.143 ± 0.033	3.305ArgIle: 3.305 ± 0.064	2.708ArgLys: 2.708 ± 0.059	5.995ArgLeu: 5.995 ± 0.092	1.373ArgMet: 1.373 ± 0.042	1.995ArgAsn: 1.995 ± 0.05	2.451ArgPro: 2.451 ± 0.055	2.038ArgGln: 2.038 ± 0.044	3.631ArgArg: 3.631 ± 0.093	3.135ArgSer: 3.135 ± 0.063	2.62ArgThr: 2.62 ± 0.067	3.785ArgVal: 3.785 ± 0.125	0.546ArgTrp: 0.546 ± 0.025	1.758ArgTyr: 1.758 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.427SerAla: 6.427 ± 0.102	0.485SerCys: 0.485 ± 0.025	4.235SerAsp: 4.235 ± 0.078	4.211SerGlu: 4.211 ± 0.081	2.761SerPhe: 2.761 ± 0.057	5.652SerGly: 5.652 ± 0.113	1.248SerHis: 1.248 ± 0.046	3.698SerIle: 3.698 ± 0.06	2.975SerLys: 2.975 ± 0.064	6.547SerLeu: 6.547 ± 0.101	1.454SerMet: 1.454 ± 0.043	2.306SerAsn: 2.306 ± 0.063	2.952SerPro: 2.952 ± 0.067	2.413SerGln: 2.413 ± 0.063	3.42SerArg: 3.42 ± 0.062	3.768SerSer: 3.768 ± 0.089	3.228SerThr: 3.228 ± 0.086	4.619SerVal: 4.619 ± 0.07	0.735SerTrp: 0.735 ± 0.026	1.744SerTyr: 1.744 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	5.681ThrAla: 5.681 ± 0.089	0.394ThrCys: 0.394 ± 0.024	3.374ThrAsp: 3.374 ± 0.056	3.377ThrGlu: 3.377 ± 0.091	2.068ThrPhe: 2.068 ± 0.05	4.781ThrGly: 4.781 ± 0.089	1.121ThrHis: 1.121 ± 0.036	3.257ThrIle: 3.257 ± 0.087	2.531ThrLys: 2.531 ± 0.073	6.343ThrLeu: 6.343 ± 0.093	1.109ThrMet: 1.109 ± 0.037	1.903ThrAsn: 1.903 ± 0.057	3.515ThrPro: 3.515 ± 0.09	2.142ThrGln: 2.142 ± 0.058	2.773ThrArg: 2.773 ± 0.074	3.511ThrSer: 3.511 ± 0.064	3.019ThrThr: 3.019 ± 0.083	4.093ThrVal: 4.093 ± 0.171	0.516ThrTrp: 0.516 ± 0.026	1.623ThrTyr: 1.623 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	5.741ValAla: 5.741 ± 0.096	0.596ValCys: 0.596 ± 0.026	3.977ValAsp: 3.977 ± 0.08	4.401ValGlu: 4.401 ± 0.085	2.769ValPhe: 2.769 ± 0.072	4.664ValGly: 4.664 ± 0.074	1.016ValHis: 1.016 ± 0.038	4.44ValIle: 4.44 ± 0.094	3.523ValLys: 3.523 ± 0.081	6.171ValLeu: 6.171 ± 0.093	1.791ValMet: 1.791 ± 0.049	2.445ValAsn: 2.445 ± 0.065	2.786ValPro: 2.786 ± 0.067	2.128ValGln: 2.128 ± 0.088	3.289ValArg: 3.289 ± 0.071	4.632ValSer: 4.632 ± 0.088	4.264ValThr: 4.264 ± 0.174	4.446ValVal: 4.446 ± 0.188	0.787ValTrp: 0.787 ± 0.03	1.686ValTyr: 1.686 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.996TrpAla: 0.996 ± 0.036	0.111TrpCys: 0.111 ± 0.012	0.696TrpAsp: 0.696 ± 0.027	0.59TrpGlu: 0.59 ± 0.026	0.47TrpPhe: 0.47 ± 0.023	0.799TrpGly: 0.799 ± 0.034	0.251TrpHis: 0.251 ± 0.018	0.588TrpIle: 0.588 ± 0.032	0.507TrpLys: 0.507 ± 0.026	1.224TrpLeu: 1.224 ± 0.048	0.335TrpMet: 0.335 ± 0.022	0.419TrpAsn: 0.419 ± 0.023	0.53TrpPro: 0.53 ± 0.024	0.487TrpGln: 0.487 ± 0.024	0.822TrpArg: 0.822 ± 0.03	0.7TrpSer: 0.7 ± 0.031	0.68TrpThr: 0.68 ± 0.025	0.805TrpVal: 0.805 ± 0.033	0.164TrpTrp: 0.164 ± 0.013	0.266TrpTyr: 0.266 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.618TyrAla: 2.618 ± 0.053	0.266TyrCys: 0.266 ± 0.021	1.947TyrAsp: 1.947 ± 0.05	1.756TyrGlu: 1.756 ± 0.059	1.27TyrPhe: 1.27 ± 0.045	2.386TyrGly: 2.386 ± 0.051	0.562TyrHis: 0.562 ± 0.023	1.555TyrIle: 1.555 ± 0.043	1.288TyrLys: 1.288 ± 0.036	2.481TyrLeu: 2.481 ± 0.064	0.588TyrMet: 0.588 ± 0.028	1.113TyrAsn: 1.113 ± 0.034	1.095TyrPro: 1.095 ± 0.034	0.925TyrGln: 0.925 ± 0.035	1.571TyrArg: 1.571 ± 0.042	1.757TyrSer: 1.757 ± 0.049	1.423TyrThr: 1.423 ± 0.041	1.778TyrVal: 1.778 ± 0.05	0.354TyrTrp: 0.354 ± 0.022	0.859TyrTyr: 0.859 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2552 proteins (835630 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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