Amino acid dipepetide frequency for Infectious pancreatic necrosis virus (strain Sp) (IPNV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.282AlaAla: 11.282 ± 1.262
0.0AlaCys: 0.0 ± 0.0
5.641AlaAsp: 5.641 ± 0.376
5.265AlaGlu: 5.265 ± 0.528
3.009AlaPhe: 3.009 ± 0.437
3.761AlaGly: 3.761 ± 1.11
1.88AlaHis: 1.88 ± 0.555
4.513AlaIle: 4.513 ± 0.182
5.641AlaLys: 5.641 ± 0.613
5.265AlaLeu: 5.265 ± 0.29
3.009AlaMet: 3.009 ± 1.383
4.137AlaAsn: 4.137 ± 0.464
7.522AlaPro: 7.522 ± 0.85
1.128AlaGln: 1.128 ± 0.901
3.385AlaArg: 3.385 ± 0.137
4.889AlaSer: 4.889 ± 0.118
7.146AlaThr: 7.146 ± 0.973
5.265AlaVal: 5.265 ± 1.04
0.752AlaTrp: 0.752 ± 0.6
2.256AlaTyr: 2.256 ± 0.632
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.376CysPhe: 0.376 ± 0.3
1.128CysGly: 1.128 ± 0.046
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.752CysLeu: 0.752 ± 0.346
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.128CysThr: 1.128 ± 0.046
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.376CysTyr: 0.376 ± 0.3
0.0CysXaa: 0.0 ± 0.0
Asp
4.513AspAla: 4.513 ± 0.764
0.0AspCys: 0.0 ± 0.0
3.009AspAsp: 3.009 ± 0.437
3.009AspGlu: 3.009 ± 1.456
3.761AspPhe: 3.761 ± 0.164
3.761AspGly: 3.761 ± 0.783
1.504AspHis: 1.504 ± 0.359
5.641AspIle: 5.641 ± 1.665
3.009AspLys: 3.009 ± 0.437
9.778AspLeu: 9.778 ± 1.657
0.376AspMet: 0.376 ± 0.3
3.009AspAsn: 3.009 ± 0.509
3.761AspPro: 3.761 ± 0.783
3.761AspGln: 3.761 ± 0.698
0.752AspArg: 0.752 ± 0.346
2.256AspSer: 2.256 ± 1.037
1.88AspThr: 1.88 ± 0.391
4.889AspVal: 4.889 ± 1.331
1.504AspTrp: 1.504 ± 0.692
0.376AspTyr: 0.376 ± 0.3
0.0AspXaa: 0.0 ± 0.0
Glu
7.146GluAla: 7.146 ± 2.355
0.0GluCys: 0.0 ± 0.0
4.137GluAsp: 4.137 ± 0.464
3.385GluGlu: 3.385 ± 1.756
3.761GluPhe: 3.761 ± 0.783
3.009GluGly: 3.009 ± 0.509
1.504GluHis: 1.504 ± 0.692
3.385GluIle: 3.385 ± 0.81
4.137GluLys: 4.137 ± 0.482
5.265GluLeu: 5.265 ± 1.365
1.504GluMet: 1.504 ± 0.692
2.633GluAsn: 2.633 ± 0.737
1.504GluPro: 1.504 ± 1.201
3.761GluGln: 3.761 ± 0.783
3.009GluArg: 3.009 ± 0.437
2.256GluSer: 2.256 ± 0.855
6.017GluThr: 6.017 ± 0.072
3.761GluVal: 3.761 ± 1.11
1.88GluTrp: 1.88 ± 0.295
1.128GluTyr: 1.128 ± 0.901
0.0GluXaa: 0.0 ± 0.0
Phe
2.256PheAla: 2.256 ± 0.855
0.0PheCys: 0.0 ± 0.0
1.88PheAsp: 1.88 ± 0.555
0.752PheGlu: 0.752 ± 0.6
0.752PhePhe: 0.752 ± 0.346
2.256PheGly: 2.256 ± 0.091
1.504PheHis: 1.504 ± 0.692
1.128PheIle: 1.128 ± 0.046
1.128PheLys: 1.128 ± 0.046
3.009PheLeu: 3.009 ± 1.383
1.128PheMet: 1.128 ± 0.046
1.504PheAsn: 1.504 ± 0.255
2.256PhePro: 2.256 ± 0.091
0.376PheGln: 0.376 ± 0.3
0.752PheArg: 0.752 ± 0.346
3.009PheSer: 3.009 ± 0.509
1.504PheThr: 1.504 ± 0.255
0.752PheVal: 0.752 ± 0.346
1.504PheTrp: 1.504 ± 0.692
1.128PheTyr: 1.128 ± 0.046
0.0PheXaa: 0.0 ± 0.0
Gly
3.385GlyAla: 3.385 ± 0.44
0.0GlyCys: 0.0 ± 0.0
5.641GlyAsp: 5.641 ± 0.228
4.137GlyGlu: 4.137 ± 0.464
1.88GlyPhe: 1.88 ± 0.391
3.761GlyGly: 3.761 ± 0.164
0.0GlyHis: 0.0 ± 0.0
3.761GlyIle: 3.761 ± 0.783
5.641GlyLys: 5.641 ± 1.174
5.265GlyLeu: 5.265 ± 1.365
0.752GlyMet: 0.752 ± 0.6
3.009GlyAsn: 3.009 ± 1.456
4.513GlyPro: 4.513 ± 1.71
1.88GlyGln: 1.88 ± 0.391
3.761GlyArg: 3.761 ± 1.11
6.017GlySer: 6.017 ± 0.072
4.513GlyThr: 4.513 ± 0.182
4.137GlyVal: 4.137 ± 2.356
2.256GlyTrp: 2.256 ± 0.631
1.88GlyTyr: 1.88 ± 0.909
0.0GlyXaa: 0.0 ± 0.0
His
1.504HisAla: 1.504 ± 0.359
0.0HisCys: 0.0 ± 0.0
0.752HisAsp: 0.752 ± 0.346
0.376HisGlu: 0.376 ± 0.3
0.376HisPhe: 0.376 ± 0.3
1.128HisGly: 1.128 ± 0.591
0.376HisHis: 0.376 ± 0.3
0.376HisIle: 0.376 ± 0.3
1.88HisLys: 1.88 ± 0.909
2.633HisLeu: 2.633 ± 0.737
1.88HisMet: 1.88 ± 0.391
0.0HisAsn: 0.0 ± 0.0
0.376HisPro: 0.376 ± 0.3
0.376HisGln: 0.376 ± 0.3
0.752HisArg: 0.752 ± 0.311
0.376HisSer: 0.376 ± 0.3
0.376HisThr: 0.376 ± 0.3
0.752HisVal: 0.752 ± 0.346
0.0HisTrp: 0.0 ± 0.0
0.376HisTyr: 0.376 ± 0.3
0.0HisXaa: 0.0 ± 0.0
Ile
3.385IleAla: 3.385 ± 0.137
0.376IleCys: 0.376 ± 0.3
1.88IleAsp: 1.88 ± 0.391
2.633IleGlu: 2.633 ± 0.737
1.128IlePhe: 1.128 ± 0.046
3.761IleGly: 3.761 ± 1.11
0.0IleHis: 0.0 ± 0.0
3.385IleIle: 3.385 ± 0.137
1.504IleLys: 1.504 ± 1.201
3.385IleLeu: 3.385 ± 0.137
2.256IleMet: 2.256 ± 0.091
3.761IleAsn: 3.761 ± 0.783
4.513IlePro: 4.513 ± 0.764
1.504IleGln: 1.504 ± 0.255
3.385IleArg: 3.385 ± 0.137
2.633IleSer: 2.633 ± 0.209
4.513IleThr: 4.513 ± 0.764
3.385IleVal: 3.385 ± 0.81
0.752IleTrp: 0.752 ± 0.346
1.88IleTyr: 1.88 ± 0.391
0.0IleXaa: 0.0 ± 0.0
Lys
5.265LysAla: 5.265 ± 0.528
0.0LysCys: 0.0 ± 0.0
4.137LysAsp: 4.137 ± 1.429
3.761LysGlu: 3.761 ± 0.164
1.128LysPhe: 1.128 ± 0.901
6.017LysGly: 6.017 ± 0.874
1.128LysHis: 1.128 ± 0.046
3.385LysIle: 3.385 ± 0.137
1.88LysLys: 1.88 ± 0.391
3.761LysLeu: 3.761 ± 0.164
1.504LysMet: 1.504 ± 1.201
3.385LysAsn: 3.385 ± 0.137
3.385LysPro: 3.385 ± 0.441
2.256LysGln: 2.256 ± 0.091
4.137LysArg: 4.137 ± 0.482
5.265LysSer: 5.265 ± 1.474
5.641LysThr: 5.641 ± 2.12
1.504LysVal: 1.504 ± 0.255
0.0LysTrp: 0.0 ± 0.0
3.009LysTyr: 3.009 ± 0.509
0.0LysXaa: 0.0 ± 0.0
Leu
8.274LeuAla: 8.274 ± 0.965
0.0LeuCys: 0.0 ± 0.0
7.898LeuAsp: 7.898 ± 1.265
9.026LeuGlu: 9.026 ± 1.311
1.128LeuPhe: 1.128 ± 0.046
2.633LeuGly: 2.633 ± 0.209
0.0LeuHis: 0.0 ± 0.0
6.393LeuIle: 6.393 ± 0.373
9.026LeuLys: 9.026 ± 0.364
11.282LeuLeu: 11.282 ± 2.835
4.889LeuMet: 4.889 ± 0.828
5.265LeuAsn: 5.265 ± 0.418
7.898LeuPro: 7.898 ± 1.574
3.009LeuGln: 3.009 ± 0.437
5.265LeuArg: 5.265 ± 1.474
4.889LeuSer: 4.889 ± 1.064
6.769LeuThr: 6.769 ± 0.273
3.009LeuVal: 3.009 ± 0.509
0.0LeuTrp: 0.0 ± 0.0
1.504LeuTyr: 1.504 ± 0.255
0.0LeuXaa: 0.0 ± 0.0
Met
3.009MetAla: 3.009 ± 1.456
0.376MetCys: 0.376 ± 0.3
1.88MetAsp: 1.88 ± 0.391
1.504MetGlu: 1.504 ± 0.692
0.752MetPhe: 0.752 ± 0.346
1.128MetGly: 1.128 ± 0.901
0.0MetHis: 0.0 ± 0.0
1.128MetIle: 1.128 ± 0.046
2.633MetLys: 2.633 ± 0.737
0.376MetLeu: 0.376 ± 0.3
0.752MetMet: 0.752 ± 0.346
2.256MetAsn: 2.256 ± 0.477
0.0MetPro: 0.0 ± 0.0
1.128MetGln: 1.128 ± 0.046
0.376MetArg: 0.376 ± 0.3
4.137MetSer: 4.137 ± 1.429
1.504MetThr: 1.504 ± 0.255
4.513MetVal: 4.513 ± 1.128
0.0MetTrp: 0.0 ± 0.0
1.504MetTyr: 1.504 ± 0.359
0.0MetXaa: 0.0 ± 0.0
Asn
5.265AsnAla: 5.265 ± 1.365
0.752AsnCys: 0.752 ± 0.346
2.633AsnAsp: 2.633 ± 1.155
3.385AsnGlu: 3.385 ± 1.083
1.128AsnPhe: 1.128 ± 0.046
1.88AsnGly: 1.88 ± 1.501
0.752AsnHis: 0.752 ± 0.346
3.009AsnIle: 3.009 ± 0.437
3.385AsnLys: 3.385 ± 0.137
2.256AsnLeu: 2.256 ± 0.091
1.128AsnMet: 1.128 ± 0.399
3.009AsnAsn: 3.009 ± 0.437
5.641AsnPro: 5.641 ± 1.672
2.633AsnGln: 2.633 ± 1.155
1.88AsnArg: 1.88 ± 0.391
1.88AsnSer: 1.88 ± 0.555
3.761AsnThr: 3.761 ± 0.783
1.504AsnVal: 1.504 ± 0.255
0.0AsnTrp: 0.0 ± 0.0
2.256AsnTyr: 2.256 ± 1.801
0.0AsnXaa: 0.0 ± 0.0
Pro
4.513ProAla: 4.513 ± 1.71
0.0ProCys: 0.0 ± 0.0
4.137ProAsp: 4.137 ± 0.464
6.393ProGlu: 6.393 ± 0.893
1.88ProPhe: 1.88 ± 0.391
6.769ProGly: 6.769 ± 1.18
1.128ProHis: 1.128 ± 0.046
2.633ProIle: 2.633 ± 1.155
5.265ProLys: 5.265 ± 1.474
6.017ProLeu: 6.017 ± 0.874
1.128ProMet: 1.128 ± 0.046
1.504ProAsn: 1.504 ± 0.359
4.137ProPro: 4.137 ± 0.464
3.009ProGln: 3.009 ± 0.437
5.265ProArg: 5.265 ± 0.528
4.137ProSer: 4.137 ± 0.464
6.393ProThr: 6.393 ± 1.084
4.137ProVal: 4.137 ± 0.464
0.0ProTrp: 0.0 ± 0.0
1.88ProTyr: 1.88 ± 0.391
0.0ProXaa: 0.0 ± 0.0
Gln
1.88GlnAla: 1.88 ± 0.909
0.0GlnCys: 0.0 ± 0.0
3.385GlnAsp: 3.385 ± 0.81
1.88GlnGlu: 1.88 ± 0.555
0.752GlnPhe: 0.752 ± 0.6
2.256GlnGly: 2.256 ± 0.091
1.128GlnHis: 1.128 ± 0.046
0.752GlnIle: 0.752 ± 0.346
1.504GlnLys: 1.504 ± 0.692
4.889GlnLeu: 4.889 ± 0.828
1.504GlnMet: 1.504 ± 0.255
1.128GlnAsn: 1.128 ± 0.046
1.128GlnPro: 1.128 ± 0.901
2.256GlnGln: 2.256 ± 0.091
2.633GlnArg: 2.633 ± 0.209
1.88GlnSer: 1.88 ± 0.555
3.385GlnThr: 3.385 ± 0.137
1.128GlnVal: 1.128 ± 0.046
0.376GlnTrp: 0.376 ± 0.3
1.504GlnTyr: 1.504 ± 0.692
0.0GlnXaa: 0.0 ± 0.0
Arg
3.385ArgAla: 3.385 ± 1.315
0.376ArgCys: 0.376 ± 0.3
1.88ArgAsp: 1.88 ± 0.391
5.265ArgGlu: 5.265 ± 1.041
1.128ArgPhe: 1.128 ± 0.046
1.88ArgGly: 1.88 ± 1.067
0.376ArgHis: 0.376 ± 0.3
2.633ArgIle: 2.633 ± 0.209
2.633ArgLys: 2.633 ± 0.209
7.898ArgLeu: 7.898 ± 0.842
0.376ArgMet: 0.376 ± 0.3
3.385ArgAsn: 3.385 ± 0.137
4.137ArgPro: 4.137 ± 0.998
1.88ArgGln: 1.88 ± 0.391
3.009ArgArg: 3.009 ± 0.509
1.88ArgSer: 1.88 ± 0.391
2.256ArgThr: 2.256 ± 0.855
1.88ArgVal: 1.88 ± 0.295
1.128ArgTrp: 1.128 ± 0.046
3.761ArgTyr: 3.761 ± 0.164
0.0ArgXaa: 0.0 ± 0.0
Ser
5.265SerAla: 5.265 ± 0.528
0.752SerCys: 0.752 ± 0.346
4.137SerAsp: 4.137 ± 1.429
2.256SerGlu: 2.256 ± 0.091
1.128SerPhe: 1.128 ± 0.046
6.017SerGly: 6.017 ± 0.072
0.752SerHis: 0.752 ± 0.6
3.761SerIle: 3.761 ± 0.164
2.633SerLys: 2.633 ± 0.209
7.146SerLeu: 7.146 ± 0.973
2.256SerMet: 2.256 ± 0.091
1.128SerAsn: 1.128 ± 0.901
5.641SerPro: 5.641 ± 2.12
0.752SerGln: 0.752 ± 0.6
2.256SerArg: 2.256 ± 0.855
4.137SerSer: 4.137 ± 0.464
6.017SerThr: 6.017 ± 0.874
2.633SerVal: 2.633 ± 0.74
1.128SerTrp: 1.128 ± 0.046
2.256SerTyr: 2.256 ± 0.091
0.0SerXaa: 0.0 ± 0.0
Thr
7.146ThrAla: 7.146 ± 1.422
0.752ThrCys: 0.752 ± 0.346
2.633ThrAsp: 2.633 ± 0.209
3.385ThrGlu: 3.385 ± 0.137
3.385ThrPhe: 3.385 ± 1.083
7.522ThrGly: 7.522 ± 0.849
1.128ThrHis: 1.128 ± 0.591
1.88ThrIle: 1.88 ± 0.391
3.009ThrLys: 3.009 ± 0.509
8.274ThrLeu: 8.274 ± 0.019
2.256ThrMet: 2.256 ± 0.091
4.513ThrAsn: 4.513 ± 0.182
6.769ThrPro: 6.769 ± 0.798
3.385ThrGln: 3.385 ± 1.083
3.761ThrArg: 3.761 ± 1.11
4.513ThrSer: 4.513 ± 0.182
3.009ThrThr: 3.009 ± 0.286
3.385ThrVal: 3.385 ± 1.315
1.504ThrTrp: 1.504 ± 0.692
1.504ThrTyr: 1.504 ± 0.255
0.0ThrXaa: 0.0 ± 0.0
Val
4.889ValAla: 4.889 ± 0.655
0.376ValCys: 0.376 ± 0.3
3.009ValAsp: 3.009 ± 0.437
3.385ValGlu: 3.385 ± 0.137
1.128ValPhe: 1.128 ± 0.901
2.633ValGly: 2.633 ± 1.242
0.376ValHis: 0.376 ± 0.3
0.376ValIle: 0.376 ± 0.3
3.385ValLys: 3.385 ± 0.584
6.017ValLeu: 6.017 ± 0.616
1.88ValMet: 1.88 ± 0.514
1.504ValAsn: 1.504 ± 0.781
3.761ValPro: 3.761 ± 0.697
1.504ValGln: 1.504 ± 0.255
3.009ValArg: 3.009 ± 0.509
3.761ValSer: 3.761 ± 0.698
4.137ValThr: 4.137 ± 0.464
3.761ValVal: 3.761 ± 0.164
1.504ValTrp: 1.504 ± 0.255
1.128ValTyr: 1.128 ± 0.046
0.0ValXaa: 0.0 ± 0.0
Trp
1.88TrpAla: 1.88 ± 0.391
0.0TrpCys: 0.0 ± 0.0
0.752TrpAsp: 0.752 ± 0.346
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.504TrpGly: 1.504 ± 0.255
0.752TrpHis: 0.752 ± 0.346
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.128TrpLeu: 1.128 ± 0.046
0.0TrpMet: 0.0 ± 0.0
1.88TrpAsn: 1.88 ± 0.391
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.504TrpArg: 1.504 ± 0.255
1.88TrpSer: 1.88 ± 0.391
1.128TrpThr: 1.128 ± 0.046
0.376TrpVal: 0.376 ± 0.3
0.0TrpTrp: 0.0 ± 0.0
1.504TrpTyr: 1.504 ± 0.692
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.504TyrAla: 1.504 ± 0.255
0.0TyrCys: 0.0 ± 0.0
1.128TyrAsp: 1.128 ± 0.901
3.385TyrGlu: 3.385 ± 1.756
0.0TyrPhe: 0.0 ± 0.0
3.385TyrGly: 3.385 ± 0.137
0.376TyrHis: 0.376 ± 0.3
1.88TyrIle: 1.88 ± 0.391
2.256TyrLys: 2.256 ± 0.855
3.761TyrLeu: 3.761 ± 0.42
0.0TyrMet: 0.0 ± 0.0
1.504TyrAsn: 1.504 ± 0.255
3.385TyrPro: 3.385 ± 1.083
0.752TyrGln: 0.752 ± 0.346
2.256TyrArg: 2.256 ± 0.476
2.256TyrSer: 2.256 ± 1.037
2.633TyrThr: 2.633 ± 0.737
0.752TyrVal: 0.752 ± 0.311
0.0TyrTrp: 0.0 ± 0.0
1.88TyrTyr: 1.88 ± 0.391
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2660 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski