Amino acid dipepetide frequency for Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.507AlaAla: 11.507 ± 0.132	1.501AlaCys: 1.501 ± 0.038	5.272AlaAsp: 5.272 ± 0.077	6.506AlaGlu: 6.506 ± 0.092	3.429AlaPhe: 3.429 ± 0.056	7.335AlaGly: 7.335 ± 0.074	1.404AlaHis: 1.404 ± 0.037	5.011AlaIle: 5.011 ± 0.073	4.479AlaLys: 4.479 ± 0.075	9.338AlaLeu: 9.338 ± 0.126	2.837AlaMet: 2.837 ± 0.048	2.734AlaAsn: 2.734 ± 0.047	3.191AlaPro: 3.191 ± 0.058	3.365AlaGln: 3.365 ± 0.058	4.227AlaArg: 4.227 ± 0.065	4.809AlaSer: 4.809 ± 0.069	4.017AlaThr: 4.017 ± 0.079	7.975AlaVal: 7.975 ± 0.092	0.811AlaTrp: 0.811 ± 0.029	2.789AlaTyr: 2.789 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.528CysAla: 1.528 ± 0.039	0.383CysCys: 0.383 ± 0.018	0.953CysAsp: 0.953 ± 0.03	0.858CysGlu: 0.858 ± 0.029	0.72CysPhe: 0.72 ± 0.025	1.887CysGly: 1.887 ± 0.045	0.394CysHis: 0.394 ± 0.018	1.037CysIle: 1.037 ± 0.031	0.795CysLys: 0.795 ± 0.027	1.39CysLeu: 1.39 ± 0.033	0.473CysMet: 0.473 ± 0.022	0.546CysAsn: 0.546 ± 0.022	0.824CysPro: 0.824 ± 0.029	0.523CysGln: 0.523 ± 0.021	1.062CysArg: 1.062 ± 0.033	0.948CysSer: 0.948 ± 0.029	0.942CysThr: 0.942 ± 0.031	1.195CysVal: 1.195 ± 0.03	0.15CysTrp: 0.15 ± 0.01	0.588CysTyr: 0.588 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	5.178AspAla: 5.178 ± 0.079	0.993AspCys: 0.993 ± 0.028	2.754AspAsp: 2.754 ± 0.056	3.773AspGlu: 3.773 ± 0.06	2.523AspPhe: 2.523 ± 0.044	4.972AspGly: 4.972 ± 0.084	0.997AspHis: 0.997 ± 0.027	3.401AspIle: 3.401 ± 0.057	2.603AspLys: 2.603 ± 0.048	4.728AspLeu: 4.728 ± 0.064	1.551AspMet: 1.551 ± 0.037	1.919AspAsn: 1.919 ± 0.049	2.151AspPro: 2.151 ± 0.047	1.494AspGln: 1.494 ± 0.038	3.006AspArg: 3.006 ± 0.058	3.118AspSer: 3.118 ± 0.057	3.155AspThr: 3.155 ± 0.059	3.771AspVal: 3.771 ± 0.063	0.744AspTrp: 0.744 ± 0.027	2.196AspTyr: 2.196 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.393GluAla: 5.393 ± 0.072	0.804GluCys: 0.804 ± 0.029	3.378GluAsp: 3.378 ± 0.055	4.501GluGlu: 4.501 ± 0.069	2.216GluPhe: 2.216 ± 0.044	3.729GluGly: 3.729 ± 0.057	1.235GluHis: 1.235 ± 0.036	4.355GluIle: 4.355 ± 0.058	4.846GluLys: 4.846 ± 0.075	6.46GluLeu: 6.46 ± 0.072	1.883GluMet: 1.883 ± 0.041	3.329GluAsn: 3.329 ± 0.056	2.053GluPro: 2.053 ± 0.046	2.736GluGln: 2.736 ± 0.058	3.699GluArg: 3.699 ± 0.065	3.321GluSer: 3.321 ± 0.054	3.689GluThr: 3.689 ± 0.06	3.653GluVal: 3.653 ± 0.053	0.575GluTrp: 0.575 ± 0.02	2.223GluTyr: 2.223 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.417PheAla: 3.417 ± 0.05	0.84PheCys: 0.84 ± 0.028	2.31PheAsp: 2.31 ± 0.042	2.088PheGlu: 2.088 ± 0.048	1.803PhePhe: 1.803 ± 0.041	3.095PheGly: 3.095 ± 0.057	0.808PheHis: 0.808 ± 0.026	2.147PheIle: 2.147 ± 0.051	1.562PheLys: 1.562 ± 0.04	3.981PheLeu: 3.981 ± 0.062	0.922PheMet: 0.922 ± 0.033	1.408PheAsn: 1.408 ± 0.036	1.635PhePro: 1.635 ± 0.037	1.39PheGln: 1.39 ± 0.031	2.041PheArg: 2.041 ± 0.043	3.101PheSer: 3.101 ± 0.06	2.495PheThr: 2.495 ± 0.042	2.458PheVal: 2.458 ± 0.049	0.444PheTrp: 0.444 ± 0.023	1.454PheTyr: 1.454 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	6.47GlyAla: 6.47 ± 0.094	1.412GlyCys: 1.412 ± 0.035	3.905GlyAsp: 3.905 ± 0.059	4.634GlyGlu: 4.634 ± 0.077	3.129GlyPhe: 3.129 ± 0.055	6.346GlyGly: 6.346 ± 0.103	1.323GlyHis: 1.323 ± 0.036	5.166GlyIle: 5.166 ± 0.071	5.008GlyLys: 5.008 ± 0.065	6.726GlyLeu: 6.726 ± 0.087	2.447GlyMet: 2.447 ± 0.049	2.826GlyAsn: 2.826 ± 0.047	1.668GlyPro: 1.668 ± 0.045	2.458GlyGln: 2.458 ± 0.049	3.89GlyArg: 3.89 ± 0.062	4.589GlySer: 4.589 ± 0.075	4.919GlyThr: 4.919 ± 0.076	5.639GlyVal: 5.639 ± 0.081	0.817GlyTrp: 0.817 ± 0.025	3.058GlyTyr: 3.058 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	1.385HisAla: 1.385 ± 0.035	0.419HisCys: 0.419 ± 0.018	0.914HisAsp: 0.914 ± 0.028	0.918HisGlu: 0.918 ± 0.029	0.812HisPhe: 0.812 ± 0.026	1.386HisGly: 1.386 ± 0.034	0.456HisHis: 0.456 ± 0.026	1.285HisIle: 1.285 ± 0.034	0.759HisLys: 0.759 ± 0.023	1.625HisLeu: 1.625 ± 0.037	0.507HisMet: 0.507 ± 0.022	0.629HisAsn: 0.629 ± 0.024	1.002HisPro: 1.002 ± 0.033	0.531HisGln: 0.531 ± 0.023	1.06HisArg: 1.06 ± 0.035	1.105HisSer: 1.105 ± 0.03	1.065HisThr: 1.065 ± 0.031	1.111HisVal: 1.111 ± 0.027	0.211HisTrp: 0.211 ± 0.015	0.713HisTyr: 0.713 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.385IleAla: 5.385 ± 0.068	1.159IleCys: 1.159 ± 0.036	3.279IleAsp: 3.279 ± 0.052	3.303IleGlu: 3.303 ± 0.052	2.272IlePhe: 2.272 ± 0.052	4.383IleGly: 4.383 ± 0.074	1.161IleHis: 1.161 ± 0.033	3.292IleIle: 3.292 ± 0.068	2.587IleLys: 2.587 ± 0.042	6.122IleLeu: 6.122 ± 0.097	1.404IleMet: 1.404 ± 0.037	2.128IleAsn: 2.128 ± 0.044	2.892IlePro: 2.892 ± 0.046	2.044IleGln: 2.044 ± 0.038	3.555IleArg: 3.555 ± 0.056	4.149IleSer: 4.149 ± 0.063	3.62IleThr: 3.62 ± 0.067	4.057IleVal: 4.057 ± 0.061	0.584IleTrp: 0.584 ± 0.025	2.015IleTyr: 2.015 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.744LysAla: 4.744 ± 0.072	0.657LysCys: 0.657 ± 0.025	2.8LysAsp: 2.8 ± 0.054	3.818LysGlu: 3.818 ± 0.057	1.507LysPhe: 1.507 ± 0.039	3.272LysGly: 3.272 ± 0.046	0.78LysHis: 0.78 ± 0.029	3.358LysIle: 3.358 ± 0.05	4.079LysLys: 4.079 ± 0.07	5.159LysLeu: 5.159 ± 0.068	1.624LysMet: 1.624 ± 0.039	2.489LysAsn: 2.489 ± 0.047	2.131LysPro: 2.131 ± 0.053	1.971LysGln: 1.971 ± 0.044	3.055LysArg: 3.055 ± 0.051	3.185LysSer: 3.185 ± 0.053	3.466LysThr: 3.466 ± 0.058	3.121LysVal: 3.121 ± 0.061	0.555LysTrp: 0.555 ± 0.022	2.023LysTyr: 2.023 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	8.521LeuAla: 8.521 ± 0.101	1.985LeuCys: 1.985 ± 0.041	5.273LeuAsp: 5.273 ± 0.067	5.579LeuGlu: 5.579 ± 0.077	3.884LeuPhe: 3.884 ± 0.072	6.536LeuGly: 6.536 ± 0.091	1.813LeuHis: 1.813 ± 0.038	5.179LeuIle: 5.179 ± 0.077	5.194LeuLys: 5.194 ± 0.065	9.937LeuLeu: 9.937 ± 0.137	2.64LeuMet: 2.64 ± 0.049	3.56LeuAsn: 3.56 ± 0.058	4.496LeuPro: 4.496 ± 0.066	2.897LeuGln: 2.897 ± 0.054	5.636LeuArg: 5.636 ± 0.084	7.143LeuSer: 7.143 ± 0.09	6.064LeuThr: 6.064 ± 0.082	5.638LeuVal: 5.638 ± 0.079	0.971LeuTrp: 0.971 ± 0.029	3.131LeuTyr: 3.131 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.635MetAla: 2.635 ± 0.058	0.355MetCys: 0.355 ± 0.016	1.833MetAsp: 1.833 ± 0.039	2.205MetGlu: 2.205 ± 0.046	0.865MetPhe: 0.865 ± 0.027	1.998MetGly: 1.998 ± 0.046	0.398MetHis: 0.398 ± 0.018	1.501MetIle: 1.501 ± 0.043	2.038MetLys: 2.038 ± 0.044	2.691MetLeu: 2.691 ± 0.058	0.808MetMet: 0.808 ± 0.026	1.279MetAsn: 1.279 ± 0.031	1.183MetPro: 1.183 ± 0.029	0.963MetGln: 0.963 ± 0.033	1.469MetArg: 1.469 ± 0.036	1.801MetSer: 1.801 ± 0.038	1.76MetThr: 1.76 ± 0.037	1.764MetVal: 1.764 ± 0.036	0.181MetTrp: 0.181 ± 0.012	0.692MetTyr: 0.692 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.334AsnAla: 3.334 ± 0.06	0.663AsnCys: 0.663 ± 0.027	1.703AsnAsp: 1.703 ± 0.038	2.049AsnGlu: 2.049 ± 0.038	1.372AsnPhe: 1.372 ± 0.034	3.326AsnGly: 3.326 ± 0.066	0.721AsnHis: 0.721 ± 0.024	2.481AsnIle: 2.481 ± 0.05	1.628AsnLys: 1.628 ± 0.035	3.656AsnLeu: 3.656 ± 0.056	1.049AsnMet: 1.049 ± 0.028	1.277AsnAsn: 1.277 ± 0.039	1.915AsnPro: 1.915 ± 0.045	1.26AsnGln: 1.26 ± 0.032	2.229AsnArg: 2.229 ± 0.042	2.171AsnSer: 2.171 ± 0.051	2.12AsnThr: 2.12 ± 0.047	2.53AsnVal: 2.53 ± 0.039	0.41AsnTrp: 0.41 ± 0.019	1.48AsnTyr: 1.48 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	3.859ProAla: 3.859 ± 0.063	0.599ProCys: 0.599 ± 0.025	2.64ProAsp: 2.64 ± 0.04	3.537ProGlu: 3.537 ± 0.061	1.655ProPhe: 1.655 ± 0.037	2.936ProGly: 2.936 ± 0.054	0.72ProHis: 0.72 ± 0.023	2.07ProIle: 2.07 ± 0.038	1.85ProLys: 1.85 ± 0.044	3.235ProLeu: 3.235 ± 0.056	1.107ProMet: 1.107 ± 0.03	1.333ProAsn: 1.333 ± 0.034	1.425ProPro: 1.425 ± 0.043	1.366ProGln: 1.366 ± 0.031	1.659ProArg: 1.659 ± 0.04	2.269ProSer: 2.269 ± 0.051	2.005ProThr: 2.005 ± 0.049	3.319ProVal: 3.319 ± 0.054	0.432ProTrp: 0.432 ± 0.019	1.418ProTyr: 1.418 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.092GlnAla: 3.092 ± 0.056	0.467GlnCys: 0.467 ± 0.02	1.569GlnAsp: 1.569 ± 0.036	2.303GlnGlu: 2.303 ± 0.052	1.236GlnPhe: 1.236 ± 0.029	2.159GlnGly: 2.159 ± 0.048	0.592GlnHis: 0.592 ± 0.019	2.27GlnIle: 2.27 ± 0.049	2.276GlnLys: 2.276 ± 0.049	3.082GlnLeu: 3.082 ± 0.057	1.113GlnMet: 1.113 ± 0.031	1.563GlnAsn: 1.563 ± 0.04	1.195GlnPro: 1.195 ± 0.029	1.372GlnGln: 1.372 ± 0.037	1.968GlnArg: 1.968 ± 0.042	2.167GlnSer: 2.167 ± 0.044	2.011GlnThr: 2.011 ± 0.046	2.085GlnVal: 2.085 ± 0.038	0.359GlnTrp: 0.359 ± 0.017	1.304GlnTyr: 1.304 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	4.288ArgAla: 4.288 ± 0.064	0.918ArgCys: 0.918 ± 0.027	2.876ArgAsp: 2.876 ± 0.052	4.162ArgGlu: 4.162 ± 0.066	2.241ArgPhe: 2.241 ± 0.054	3.421ArgGly: 3.421 ± 0.06	1.089ArgHis: 1.089 ± 0.029	3.319ArgIle: 3.319 ± 0.05	3.343ArgLys: 3.343 ± 0.05	5.224ArgLeu: 5.224 ± 0.074	1.716ArgMet: 1.716 ± 0.037	2.06ArgAsn: 2.06 ± 0.042	2.02ArgPro: 2.02 ± 0.049	2.252ArgGln: 2.252 ± 0.048	3.962ArgArg: 3.962 ± 0.072	2.82ArgSer: 2.82 ± 0.052	2.831ArgThr: 2.831 ± 0.048	3.299ArgVal: 3.299 ± 0.053	0.606ArgTrp: 0.606 ± 0.024	2.022ArgTyr: 2.022 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.153SerAla: 6.153 ± 0.081	0.959SerCys: 0.959 ± 0.028	3.486SerAsp: 3.486 ± 0.058	3.575SerGlu: 3.575 ± 0.055	2.606SerPhe: 2.606 ± 0.046	6.06SerGly: 6.06 ± 0.082	1.032SerHis: 1.032 ± 0.031	3.657SerIle: 3.657 ± 0.061	2.751SerLys: 2.751 ± 0.058	5.513SerLeu: 5.513 ± 0.07	1.768SerMet: 1.768 ± 0.035	2.136SerAsn: 2.136 ± 0.049	2.304SerPro: 2.304 ± 0.044	1.915SerGln: 1.915 ± 0.039	3.177SerArg: 3.177 ± 0.058	4.092SerSer: 4.092 ± 0.085	3.276SerThr: 3.276 ± 0.066	4.65SerVal: 4.65 ± 0.073	0.602SerTrp: 0.602 ± 0.023	2.087SerTyr: 2.087 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	6.254ThrAla: 6.254 ± 0.085	0.791ThrCys: 0.791 ± 0.03	3.341ThrAsp: 3.341 ± 0.058	3.458ThrGlu: 3.458 ± 0.058	2.176ThrPhe: 2.176 ± 0.049	5.19ThrGly: 5.19 ± 0.092	0.982ThrHis: 0.982 ± 0.029	3.317ThrIle: 3.317 ± 0.063	2.31ThrLys: 2.31 ± 0.046	5.669ThrLeu: 5.669 ± 0.074	1.53ThrMet: 1.53 ± 0.038	1.754ThrAsn: 1.754 ± 0.045	2.711ThrPro: 2.711 ± 0.049	1.741ThrGln: 1.741 ± 0.042	2.396ThrArg: 2.396 ± 0.05	3.062ThrSer: 3.062 ± 0.053	2.994ThrThr: 2.994 ± 0.078	5.441ThrVal: 5.441 ± 0.083	0.537ThrTrp: 0.537 ± 0.022	1.971ThrTyr: 1.971 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	5.631ValAla: 5.631 ± 0.081	1.382ValCys: 1.382 ± 0.038	3.846ValAsp: 3.846 ± 0.057	4.131ValGlu: 4.131 ± 0.057	2.974ValPhe: 2.974 ± 0.058	4.832ValGly: 4.832 ± 0.068	1.056ValHis: 1.056 ± 0.027	4.015ValIle: 4.015 ± 0.069	3.54ValLys: 3.54 ± 0.052	7.111ValLeu: 7.111 ± 0.087	1.944ValMet: 1.944 ± 0.037	2.513ValAsn: 2.513 ± 0.045	2.963ValPro: 2.963 ± 0.057	2.211ValGln: 2.211 ± 0.038	3.63ValArg: 3.63 ± 0.062	5.187ValSer: 5.187 ± 0.067	4.482ValThr: 4.482 ± 0.076	4.833ValVal: 4.833 ± 0.071	0.69ValTrp: 0.69 ± 0.025	2.36ValTyr: 2.36 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.798TrpAla: 0.798 ± 0.026	0.207TrpCys: 0.207 ± 0.012	0.604TrpAsp: 0.604 ± 0.021	0.582TrpGlu: 0.582 ± 0.023	0.429TrpPhe: 0.429 ± 0.022	0.735TrpGly: 0.735 ± 0.025	0.186TrpHis: 0.186 ± 0.012	0.516TrpIle: 0.516 ± 0.023	0.625TrpLys: 0.625 ± 0.023	1.052TrpLeu: 1.052 ± 0.028	0.315TrpMet: 0.315 ± 0.016	0.515TrpAsn: 0.515 ± 0.021	0.299TrpPro: 0.299 ± 0.017	0.394TrpGln: 0.394 ± 0.019	0.572TrpArg: 0.572 ± 0.024	0.605TrpSer: 0.605 ± 0.025	0.542TrpThr: 0.542 ± 0.025	0.66TrpVal: 0.66 ± 0.024	0.112TrpTrp: 0.112 ± 0.011	0.397TrpTyr: 0.397 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.966TyrAla: 2.966 ± 0.057	0.698TyrCys: 0.698 ± 0.027	2.289TyrAsp: 2.289 ± 0.046	2.098TyrGlu: 2.098 ± 0.036	1.549TyrPhe: 1.549 ± 0.037	2.831TyrGly: 2.831 ± 0.051	0.743TyrHis: 0.743 ± 0.026	2.013TyrIle: 2.013 ± 0.042	1.524TyrLys: 1.524 ± 0.038	3.38TyrLeu: 3.38 ± 0.066	0.782TyrMet: 0.782 ± 0.026	1.375TyrAsn: 1.375 ± 0.038	1.375TyrPro: 1.375 ± 0.033	1.304TyrGln: 1.304 ± 0.031	2.179TyrArg: 2.179 ± 0.045	2.154TyrSer: 2.154 ± 0.046	2.171TyrThr: 2.171 ± 0.058	2.134TyrVal: 2.134 ± 0.041	0.353TyrTrp: 0.353 ± 0.016	1.479TyrTyr: 1.479 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4593 proteins (1245691 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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