Amino acid dipepetide frequency for Tupaia paramyxovirus (TPMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.791AlaAla: 5.791 ± 1.291
1.121AlaCys: 1.121 ± 0.37
1.681AlaAsp: 1.681 ± 0.615
2.802AlaGlu: 2.802 ± 0.397
2.429AlaPhe: 2.429 ± 0.446
3.736AlaGly: 3.736 ± 0.933
1.308AlaHis: 1.308 ± 0.183
5.231AlaIle: 5.231 ± 0.874
3.176AlaLys: 3.176 ± 1.058
5.791AlaLeu: 5.791 ± 1.134
1.868AlaMet: 1.868 ± 0.536
1.308AlaAsn: 1.308 ± 0.388
2.802AlaPro: 2.802 ± 1.551
2.055AlaGln: 2.055 ± 0.733
3.363AlaArg: 3.363 ± 0.397
4.297AlaSer: 4.297 ± 0.913
3.176AlaThr: 3.176 ± 0.728
2.615AlaVal: 2.615 ± 1.127
0.56AlaTrp: 0.56 ± 0.232
2.429AlaTyr: 2.429 ± 0.517
0.0AlaXaa: 0.0 ± 0.0
Cys
0.374CysAla: 0.374 ± 0.357
0.56CysCys: 0.56 ± 0.35
1.121CysAsp: 1.121 ± 0.525
0.747CysGlu: 0.747 ± 0.281
0.374CysPhe: 0.374 ± 0.234
1.121CysGly: 1.121 ± 0.405
0.374CysHis: 0.374 ± 0.197
0.934CysIle: 0.934 ± 0.384
1.121CysLys: 1.121 ± 0.336
1.868CysLeu: 1.868 ± 0.635
0.187CysMet: 0.187 ± 0.117
1.494CysAsn: 1.494 ± 0.752
1.868CysPro: 1.868 ± 0.684
1.494CysGln: 1.494 ± 0.344
0.374CysArg: 0.374 ± 0.313
1.868CysSer: 1.868 ± 0.514
0.56CysThr: 0.56 ± 0.232
0.934CysVal: 0.934 ± 0.329
0.187CysTrp: 0.187 ± 0.228
1.308CysTyr: 1.308 ± 0.505
0.0CysXaa: 0.0 ± 0.0
Asp
3.363AspAla: 3.363 ± 1.291
1.308AspCys: 1.308 ± 0.79
3.176AspAsp: 3.176 ± 0.663
3.923AspGlu: 3.923 ± 1.562
2.242AspPhe: 2.242 ± 0.646
4.483AspGly: 4.483 ± 1.435
1.868AspHis: 1.868 ± 0.47
2.242AspIle: 2.242 ± 0.667
2.429AspLys: 2.429 ± 0.982
6.538AspLeu: 6.538 ± 1.266
0.56AspMet: 0.56 ± 0.252
3.176AspAsn: 3.176 ± 0.402
4.297AspPro: 4.297 ± 1.02
3.176AspGln: 3.176 ± 0.923
2.055AspArg: 2.055 ± 0.255
4.297AspSer: 4.297 ± 0.933
3.363AspThr: 3.363 ± 0.487
4.11AspVal: 4.11 ± 1.2
0.374AspTrp: 0.374 ± 0.197
2.802AspTyr: 2.802 ± 0.667
0.0AspXaa: 0.0 ± 0.0
Glu
2.242GluAla: 2.242 ± 0.246
0.747GluCys: 0.747 ± 0.263
4.67GluAsp: 4.67 ± 1.413
3.363GluGlu: 3.363 ± 2.358
1.308GluPhe: 1.308 ± 0.66
4.297GluGly: 4.297 ± 1.235
1.121GluHis: 1.121 ± 0.562
3.923GluIle: 3.923 ± 1.153
1.868GluLys: 1.868 ± 0.832
6.352GluLeu: 6.352 ± 1.57
1.308GluMet: 1.308 ± 0.528
1.121GluAsn: 1.121 ± 0.587
2.242GluPro: 2.242 ± 0.503
3.176GluGln: 3.176 ± 0.931
1.868GluArg: 1.868 ± 0.549
5.418GluSer: 5.418 ± 1.084
4.11GluThr: 4.11 ± 1.548
3.176GluVal: 3.176 ± 0.722
0.747GluTrp: 0.747 ± 0.34
1.494GluTyr: 1.494 ± 0.351
0.0GluXaa: 0.0 ± 0.0
Phe
1.494PheAla: 1.494 ± 0.863
1.121PheCys: 1.121 ± 0.525
1.681PheAsp: 1.681 ± 0.647
1.868PheGlu: 1.868 ± 0.757
1.308PhePhe: 1.308 ± 0.818
1.868PheGly: 1.868 ± 0.723
0.747PheHis: 0.747 ± 0.436
2.429PheIle: 2.429 ± 0.617
1.494PheLys: 1.494 ± 0.289
2.989PheLeu: 2.989 ± 0.908
1.121PheMet: 1.121 ± 0.453
2.055PheAsn: 2.055 ± 0.656
1.494PhePro: 1.494 ± 0.681
1.308PheGln: 1.308 ± 0.899
1.681PheArg: 1.681 ± 0.646
2.055PheSer: 2.055 ± 0.589
1.494PheThr: 1.494 ± 0.62
0.934PheVal: 0.934 ± 0.444
0.934PheTrp: 0.934 ± 0.378
0.374PheTyr: 0.374 ± 0.185
0.0PheXaa: 0.0 ± 0.0
Gly
3.923GlyAla: 3.923 ± 1.401
1.121GlyCys: 1.121 ± 0.463
3.736GlyAsp: 3.736 ± 0.635
2.429GlyGlu: 2.429 ± 1.043
1.494GlyPhe: 1.494 ± 0.288
3.363GlyGly: 3.363 ± 0.782
2.615GlyHis: 2.615 ± 0.645
3.176GlyIle: 3.176 ± 0.506
3.549GlyLys: 3.549 ± 1.191
6.165GlyLeu: 6.165 ± 0.541
1.308GlyMet: 1.308 ± 0.484
3.549GlyAsn: 3.549 ± 0.598
2.429GlyPro: 2.429 ± 0.649
1.308GlyGln: 1.308 ± 0.496
4.483GlyArg: 4.483 ± 1.172
4.297GlySer: 4.297 ± 0.995
2.615GlyThr: 2.615 ± 1.02
4.67GlyVal: 4.67 ± 0.891
0.374GlyTrp: 0.374 ± 0.322
2.429GlyTyr: 2.429 ± 0.705
0.0GlyXaa: 0.0 ± 0.0
His
0.56HisAla: 0.56 ± 0.288
0.934HisCys: 0.934 ± 0.282
1.121HisAsp: 1.121 ± 0.317
0.934HisGlu: 0.934 ± 0.387
0.374HisPhe: 0.374 ± 0.214
0.934HisGly: 0.934 ± 0.267
1.121HisHis: 1.121 ± 0.515
2.242HisIle: 2.242 ± 0.466
2.242HisLys: 2.242 ± 0.655
2.802HisLeu: 2.802 ± 0.522
0.56HisMet: 0.56 ± 0.35
0.934HisAsn: 0.934 ± 0.267
0.934HisPro: 0.934 ± 0.259
0.747HisGln: 0.747 ± 0.38
1.868HisArg: 1.868 ± 0.564
2.055HisSer: 2.055 ± 0.542
1.121HisThr: 1.121 ± 0.46
0.56HisVal: 0.56 ± 0.288
0.187HisTrp: 0.187 ± 0.117
0.374HisTyr: 0.374 ± 0.185
0.0HisXaa: 0.0 ± 0.0
Ile
4.11IleAla: 4.11 ± 0.834
0.747IleCys: 0.747 ± 0.561
4.11IleAsp: 4.11 ± 0.859
4.857IleGlu: 4.857 ± 0.704
1.868IlePhe: 1.868 ± 0.714
2.055IleGly: 2.055 ± 0.582
0.934IleHis: 0.934 ± 0.403
5.791IleIle: 5.791 ± 1.115
4.67IleLys: 4.67 ± 0.702
6.538IleLeu: 6.538 ± 1.441
1.868IleMet: 1.868 ± 0.654
5.418IleAsn: 5.418 ± 0.598
2.242IlePro: 2.242 ± 0.767
4.11IleGln: 4.11 ± 1.262
3.363IleArg: 3.363 ± 1.2
4.483IleSer: 4.483 ± 1.061
5.418IleThr: 5.418 ± 1.22
2.615IleVal: 2.615 ± 0.513
0.56IleTrp: 0.56 ± 0.42
3.363IleTyr: 3.363 ± 1.008
0.0IleXaa: 0.0 ± 0.0
Lys
3.736LysAla: 3.736 ± 0.556
0.56LysCys: 0.56 ± 0.466
3.923LysAsp: 3.923 ± 0.826
5.044LysGlu: 5.044 ± 1.579
1.681LysPhe: 1.681 ± 0.714
2.989LysGly: 2.989 ± 0.904
0.934LysHis: 0.934 ± 0.495
4.297LysIle: 4.297 ± 1.171
3.176LysLys: 3.176 ± 1.203
6.725LysLeu: 6.725 ± 1.417
1.868LysMet: 1.868 ± 0.537
2.429LysAsn: 2.429 ± 0.965
1.494LysPro: 1.494 ± 0.495
2.242LysGln: 2.242 ± 0.86
3.176LysArg: 3.176 ± 0.956
4.483LysSer: 4.483 ± 0.561
4.857LysThr: 4.857 ± 0.97
2.242LysVal: 2.242 ± 0.544
0.0LysTrp: 0.0 ± 0.0
3.176LysTyr: 3.176 ± 0.848
0.0LysXaa: 0.0 ± 0.0
Leu
7.099LeuAla: 7.099 ± 0.822
0.747LeuCys: 0.747 ± 0.344
6.912LeuAsp: 6.912 ± 0.856
4.67LeuGlu: 4.67 ± 0.513
3.176LeuPhe: 3.176 ± 0.902
7.286LeuGly: 7.286 ± 0.862
2.429LeuHis: 2.429 ± 0.533
6.725LeuIle: 6.725 ± 1.133
7.846LeuLys: 7.846 ± 1.243
9.154LeuLeu: 9.154 ± 1.154
3.176LeuMet: 3.176 ± 0.78
4.297LeuAsn: 4.297 ± 0.769
2.802LeuPro: 2.802 ± 0.75
4.297LeuGln: 4.297 ± 0.758
4.11LeuArg: 4.11 ± 0.485
9.154LeuSer: 9.154 ± 0.853
7.099LeuThr: 7.099 ± 1.836
5.791LeuVal: 5.791 ± 1.067
1.121LeuTrp: 1.121 ± 0.434
3.176LeuTyr: 3.176 ± 0.93
0.0LeuXaa: 0.0 ± 0.0
Met
1.681MetAla: 1.681 ± 0.578
0.374MetCys: 0.374 ± 0.231
1.681MetAsp: 1.681 ± 0.398
0.747MetGlu: 0.747 ± 0.488
0.934MetPhe: 0.934 ± 0.259
0.747MetGly: 0.747 ± 0.43
0.374MetHis: 0.374 ± 0.331
1.868MetIle: 1.868 ± 0.811
1.121MetLys: 1.121 ± 0.55
2.429MetLeu: 2.429 ± 0.466
0.374MetMet: 0.374 ± 0.244
1.494MetAsn: 1.494 ± 0.335
1.494MetPro: 1.494 ± 0.499
0.56MetGln: 0.56 ± 0.279
1.308MetArg: 1.308 ± 0.506
1.308MetSer: 1.308 ± 0.469
2.242MetThr: 2.242 ± 0.395
1.308MetVal: 1.308 ± 0.422
0.56MetTrp: 0.56 ± 0.232
1.494MetTyr: 1.494 ± 0.689
0.0MetXaa: 0.0 ± 0.0
Asn
2.802AsnAla: 2.802 ± 1.106
0.56AsnCys: 0.56 ± 0.472
2.242AsnAsp: 2.242 ± 0.462
2.242AsnGlu: 2.242 ± 0.501
1.868AsnPhe: 1.868 ± 0.527
3.176AsnGly: 3.176 ± 0.8
1.121AsnHis: 1.121 ± 0.358
4.11AsnIle: 4.11 ± 1.237
2.242AsnLys: 2.242 ± 0.651
6.538AsnLeu: 6.538 ± 0.804
0.374AsnMet: 0.374 ± 0.207
2.802AsnAsn: 2.802 ± 0.81
4.11AsnPro: 4.11 ± 0.713
3.176AsnGln: 3.176 ± 0.833
2.055AsnArg: 2.055 ± 0.815
5.604AsnSer: 5.604 ± 1.195
2.802AsnThr: 2.802 ± 0.824
0.747AsnVal: 0.747 ± 0.23
1.121AsnTrp: 1.121 ± 0.555
1.494AsnTyr: 1.494 ± 0.543
0.0AsnXaa: 0.0 ± 0.0
Pro
2.429ProAla: 2.429 ± 0.563
1.308ProCys: 1.308 ± 0.734
4.297ProAsp: 4.297 ± 1.044
2.989ProGlu: 2.989 ± 0.685
0.56ProPhe: 0.56 ± 0.252
2.802ProGly: 2.802 ± 1.199
0.934ProHis: 0.934 ± 0.401
2.055ProIle: 2.055 ± 0.698
3.736ProLys: 3.736 ± 1.045
3.923ProLeu: 3.923 ± 1.101
1.494ProMet: 1.494 ± 0.187
3.176ProAsn: 3.176 ± 0.717
3.736ProPro: 3.736 ± 1.123
1.121ProGln: 1.121 ± 0.475
2.615ProArg: 2.615 ± 1.0
4.857ProSer: 4.857 ± 0.91
2.429ProThr: 2.429 ± 0.506
2.615ProVal: 2.615 ± 0.495
0.374ProTrp: 0.374 ± 0.21
2.802ProTyr: 2.802 ± 1.554
0.0ProXaa: 0.0 ± 0.0
Gln
2.055GlnAla: 2.055 ± 0.381
1.121GlnCys: 1.121 ± 0.696
2.055GlnAsp: 2.055 ± 0.547
2.802GlnGlu: 2.802 ± 0.84
1.494GlnPhe: 1.494 ± 0.433
2.615GlnGly: 2.615 ± 0.451
1.494GlnHis: 1.494 ± 0.757
2.242GlnIle: 2.242 ± 0.262
2.242GlnLys: 2.242 ± 0.74
3.923GlnLeu: 3.923 ± 0.834
1.681GlnMet: 1.681 ± 0.549
1.121GlnAsn: 1.121 ± 0.635
2.429GlnPro: 2.429 ± 1.133
1.308GlnGln: 1.308 ± 0.499
2.429GlnArg: 2.429 ± 0.792
4.11GlnSer: 4.11 ± 1.142
2.429GlnThr: 2.429 ± 0.628
1.308GlnVal: 1.308 ± 0.431
0.374GlnTrp: 0.374 ± 0.185
1.308GlnTyr: 1.308 ± 0.327
0.0GlnXaa: 0.0 ± 0.0
Arg
2.802ArgAla: 2.802 ± 0.509
1.308ArgCys: 1.308 ± 0.518
3.363ArgAsp: 3.363 ± 0.668
2.055ArgGlu: 2.055 ± 0.701
1.868ArgPhe: 1.868 ± 0.865
1.681ArgGly: 1.681 ± 0.815
0.56ArgHis: 0.56 ± 0.35
3.176ArgIle: 3.176 ± 0.509
1.868ArgLys: 1.868 ± 1.042
5.231ArgLeu: 5.231 ± 0.838
1.121ArgMet: 1.121 ± 0.365
3.363ArgAsn: 3.363 ± 0.649
3.363ArgPro: 3.363 ± 1.42
1.308ArgGln: 1.308 ± 0.392
2.615ArgArg: 2.615 ± 0.809
5.231ArgSer: 5.231 ± 0.686
2.242ArgThr: 2.242 ± 0.796
3.549ArgVal: 3.549 ± 0.62
0.934ArgTrp: 0.934 ± 0.32
2.055ArgTyr: 2.055 ± 0.445
0.0ArgXaa: 0.0 ± 0.0
Ser
3.736SerAla: 3.736 ± 0.586
2.242SerCys: 2.242 ± 0.604
4.857SerAsp: 4.857 ± 1.567
4.11SerGlu: 4.11 ± 0.575
2.989SerPhe: 2.989 ± 0.803
6.725SerGly: 6.725 ± 1.36
2.615SerHis: 2.615 ± 0.699
6.352SerIle: 6.352 ± 1.252
6.352SerLys: 6.352 ± 1.473
8.967SerLeu: 8.967 ± 1.363
2.055SerMet: 2.055 ± 0.423
5.604SerAsn: 5.604 ± 1.153
3.176SerPro: 3.176 ± 0.614
2.242SerGln: 2.242 ± 0.775
3.363SerArg: 3.363 ± 0.495
8.033SerSer: 8.033 ± 1.575
7.099SerThr: 7.099 ± 0.814
3.363SerVal: 3.363 ± 0.88
0.934SerTrp: 0.934 ± 0.314
3.176SerTyr: 3.176 ± 0.595
0.0SerXaa: 0.0 ± 0.0
Thr
3.363ThrAla: 3.363 ± 0.801
0.56ThrCys: 0.56 ± 0.408
3.736ThrAsp: 3.736 ± 0.675
4.11ThrGlu: 4.11 ± 0.569
1.494ThrPhe: 1.494 ± 0.609
2.802ThrGly: 2.802 ± 0.474
0.934ThrHis: 0.934 ± 0.401
4.857ThrIle: 4.857 ± 0.696
4.11ThrLys: 4.11 ± 0.768
5.791ThrLeu: 5.791 ± 1.211
1.494ThrMet: 1.494 ± 0.45
2.055ThrAsn: 2.055 ± 0.311
3.736ThrPro: 3.736 ± 0.998
2.802ThrGln: 2.802 ± 0.249
3.549ThrArg: 3.549 ± 0.439
5.604ThrSer: 5.604 ± 0.815
3.549ThrThr: 3.549 ± 0.837
4.11ThrVal: 4.11 ± 0.483
0.934ThrTrp: 0.934 ± 0.331
2.615ThrTyr: 2.615 ± 0.701
0.0ThrXaa: 0.0 ± 0.0
Val
3.363ValAla: 3.363 ± 0.319
1.121ValCys: 1.121 ± 0.357
2.615ValAsp: 2.615 ± 0.63
2.802ValGlu: 2.802 ± 0.851
1.868ValPhe: 1.868 ± 0.743
3.176ValGly: 3.176 ± 0.961
0.374ValHis: 0.374 ± 0.322
3.923ValIle: 3.923 ± 0.674
2.242ValLys: 2.242 ± 0.529
2.615ValLeu: 2.615 ± 0.583
0.934ValMet: 0.934 ± 0.255
2.615ValAsn: 2.615 ± 0.918
2.615ValPro: 2.615 ± 0.392
1.868ValGln: 1.868 ± 0.43
4.11ValArg: 4.11 ± 0.887
3.923ValSer: 3.923 ± 0.609
3.549ValThr: 3.549 ± 0.759
3.176ValVal: 3.176 ± 0.835
0.374ValTrp: 0.374 ± 0.354
2.429ValTyr: 2.429 ± 0.632
0.0ValXaa: 0.0 ± 0.0
Trp
0.56TrpAla: 0.56 ± 0.232
0.374TrpCys: 0.374 ± 0.328
0.747TrpAsp: 0.747 ± 0.307
0.374TrpGlu: 0.374 ± 0.185
0.374TrpPhe: 0.374 ± 0.234
0.747TrpGly: 0.747 ± 0.517
0.0TrpHis: 0.0 ± 0.0
0.747TrpIle: 0.747 ± 0.263
0.747TrpLys: 0.747 ± 0.304
1.308TrpLeu: 1.308 ± 0.494
0.187TrpMet: 0.187 ± 0.117
0.934TrpAsn: 0.934 ± 0.444
0.56TrpPro: 0.56 ± 0.279
0.0TrpGln: 0.0 ± 0.0
0.56TrpArg: 0.56 ± 0.28
1.494TrpSer: 1.494 ± 0.207
0.56TrpThr: 0.56 ± 0.23
0.374TrpVal: 0.374 ± 0.185
0.187TrpTrp: 0.187 ± 0.117
0.187TrpTyr: 0.187 ± 0.117
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.055TyrAla: 2.055 ± 0.725
0.934TyrCys: 0.934 ± 0.331
2.055TyrAsp: 2.055 ± 0.556
1.681TyrGlu: 1.681 ± 0.713
0.747TyrPhe: 0.747 ± 0.437
2.429TyrGly: 2.429 ± 0.63
0.747TyrHis: 0.747 ± 0.284
2.802TyrIle: 2.802 ± 0.834
2.802TyrLys: 2.802 ± 0.621
5.418TyrLeu: 5.418 ± 1.086
0.374TyrMet: 0.374 ± 0.21
2.242TyrAsn: 2.242 ± 0.539
2.615TyrPro: 2.615 ± 0.753
2.242TyrGln: 2.242 ± 0.621
0.747TyrArg: 0.747 ± 0.36
5.418TyrSer: 5.418 ± 0.86
1.494TyrThr: 1.494 ± 0.47
1.494TyrVal: 1.494 ± 0.764
0.187TyrTrp: 0.187 ± 0.117
2.802TyrTyr: 2.802 ± 0.866
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski