Amino acid dipepetide frequency for Strawberry mild yellow edge-associated virus (SMYEaV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.606AlaAla: 9.606 ± 3.485
0.961AlaCys: 0.961 ± 0.878
3.362AlaAsp: 3.362 ± 1.032
4.323AlaGlu: 4.323 ± 2.306
4.803AlaPhe: 4.803 ± 3.469
4.323AlaGly: 4.323 ± 1.177
2.882AlaHis: 2.882 ± 1.105
4.323AlaIle: 4.323 ± 2.258
4.323AlaLys: 4.323 ± 1.749
9.606AlaLeu: 9.606 ± 2.413
1.921AlaMet: 1.921 ± 0.531
4.323AlaAsn: 4.323 ± 1.311
5.764AlaPro: 5.764 ± 2.22
2.882AlaGln: 2.882 ± 0.608
3.362AlaArg: 3.362 ± 1.292
8.646AlaSer: 8.646 ± 4.03
6.724AlaThr: 6.724 ± 1.678
2.882AlaVal: 2.882 ± 2.06
0.48AlaTrp: 0.48 ± 0.256
2.402AlaTyr: 2.402 ± 1.281
0.0AlaXaa: 0.0 ± 0.0
Cys
1.921CysAla: 1.921 ± 0.888
0.48CysCys: 0.48 ± 0.908
0.48CysAsp: 0.48 ± 0.756
1.441CysGlu: 1.441 ± 0.776
0.0CysPhe: 0.0 ± 0.0
1.441CysGly: 1.441 ± 0.568
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.961CysLys: 0.961 ± 0.878
0.961CysLeu: 0.961 ± 1.512
0.48CysMet: 0.48 ± 0.723
0.48CysAsn: 0.48 ± 0.256
0.48CysPro: 0.48 ± 0.921
1.441CysGln: 1.441 ± 0.769
0.961CysArg: 0.961 ± 0.825
3.842CysSer: 3.842 ± 2.383
2.402CysThr: 2.402 ± 0.596
0.48CysVal: 0.48 ± 0.256
0.961CysTrp: 0.961 ± 0.618
1.441CysTyr: 1.441 ± 1.611
0.0CysXaa: 0.0 ± 0.0
Asp
3.842AspAla: 3.842 ± 0.891
0.48AspCys: 0.48 ± 0.256
3.842AspAsp: 3.842 ± 2.05
4.323AspGlu: 4.323 ± 1.387
3.362AspPhe: 3.362 ± 0.738
3.362AspGly: 3.362 ± 1.256
0.48AspHis: 0.48 ± 0.908
2.402AspIle: 2.402 ± 0.796
0.961AspLys: 0.961 ± 0.512
6.724AspLeu: 6.724 ± 0.977
0.48AspMet: 0.48 ± 0.252
1.441AspAsn: 1.441 ± 0.95
4.323AspPro: 4.323 ± 1.93
1.441AspGln: 1.441 ± 0.639
2.882AspArg: 2.882 ± 0.608
3.842AspSer: 3.842 ± 1.413
4.323AspThr: 4.323 ± 1.387
4.803AspVal: 4.803 ± 2.035
1.921AspTrp: 1.921 ± 1.025
1.921AspTyr: 1.921 ± 1.025
0.0AspXaa: 0.0 ± 0.0
Glu
5.283GluAla: 5.283 ± 1.732
1.921GluCys: 1.921 ± 0.822
1.441GluAsp: 1.441 ± 0.769
2.402GluGlu: 2.402 ± 0.596
2.882GluPhe: 2.882 ± 1.136
1.441GluGly: 1.441 ± 0.568
1.441GluHis: 1.441 ± 0.769
5.283GluIle: 5.283 ± 1.655
3.362GluLys: 3.362 ± 1.183
5.764GluLeu: 5.764 ± 1.794
0.0GluMet: 0.0 ± 0.0
1.921GluAsn: 1.921 ± 1.025
3.842GluPro: 3.842 ± 0.981
0.48GluGln: 0.48 ± 0.723
2.402GluArg: 2.402 ± 2.401
1.441GluSer: 1.441 ± 0.776
1.921GluThr: 1.921 ± 0.74
3.842GluVal: 3.842 ± 0.891
0.48GluTrp: 0.48 ± 0.256
1.441GluTyr: 1.441 ± 0.568
0.0GluXaa: 0.0 ± 0.0
Phe
2.882PheAla: 2.882 ± 1.105
0.961PheCys: 0.961 ± 0.512
5.283PheAsp: 5.283 ± 1.61
3.842PheGlu: 3.842 ± 1.942
0.961PhePhe: 0.961 ± 0.632
2.402PheGly: 2.402 ± 1.077
0.961PheHis: 0.961 ± 0.632
1.921PheIle: 1.921 ± 1.025
2.402PheLys: 2.402 ± 1.281
5.283PheLeu: 5.283 ± 1.732
0.961PheMet: 0.961 ± 0.878
0.961PheAsn: 0.961 ± 0.618
2.882PhePro: 2.882 ± 0.966
1.441PheGln: 1.441 ± 0.568
0.961PheArg: 0.961 ± 1.048
2.402PheSer: 2.402 ± 0.944
1.921PheThr: 1.921 ± 0.686
1.921PheVal: 1.921 ± 1.477
0.961PheTrp: 0.961 ± 0.512
1.441PheTyr: 1.441 ± 0.639
0.0PheXaa: 0.0 ± 0.0
Gly
4.323GlyAla: 4.323 ± 1.047
1.441GlyCys: 1.441 ± 1.047
5.764GlyAsp: 5.764 ± 1.44
0.961GlyGlu: 0.961 ± 0.512
1.441GlyPhe: 1.441 ± 0.639
2.402GlyGly: 2.402 ± 1.019
0.48GlyHis: 0.48 ± 0.256
1.441GlyIle: 1.441 ± 0.848
5.764GlyLys: 5.764 ± 1.594
5.283GlyLeu: 5.283 ± 1.549
0.961GlyMet: 0.961 ± 0.512
2.402GlyAsn: 2.402 ± 0.905
4.803GlyPro: 4.803 ± 3.335
0.961GlyGln: 0.961 ± 0.825
2.402GlyArg: 2.402 ± 0.858
3.362GlySer: 3.362 ± 1.868
2.882GlyThr: 2.882 ± 2.2
2.882GlyVal: 2.882 ± 0.858
0.961GlyTrp: 0.961 ± 0.512
1.441GlyTyr: 1.441 ± 0.776
0.0GlyXaa: 0.0 ± 0.0
His
2.402HisAla: 2.402 ± 0.774
0.961HisCys: 0.961 ± 1.446
0.961HisAsp: 0.961 ± 0.632
0.961HisGlu: 0.961 ± 0.512
2.402HisPhe: 2.402 ± 0.849
1.921HisGly: 1.921 ± 1.025
0.48HisHis: 0.48 ± 0.256
0.0HisIle: 0.0 ± 0.0
0.961HisLys: 0.961 ± 0.632
2.882HisLeu: 2.882 ± 2.275
0.48HisMet: 0.48 ± 0.256
1.921HisAsn: 1.921 ± 0.888
2.402HisPro: 2.402 ± 2.243
0.961HisGln: 0.961 ± 0.512
2.402HisArg: 2.402 ± 0.903
2.882HisSer: 2.882 ± 1.742
1.921HisThr: 1.921 ± 0.888
0.48HisVal: 0.48 ± 0.256
0.0HisTrp: 0.0 ± 0.0
0.48HisTyr: 0.48 ± 0.756
0.0HisXaa: 0.0 ± 0.0
Ile
3.362IleAla: 3.362 ± 1.562
0.961IleCys: 0.961 ± 1.301
1.441IleAsp: 1.441 ± 0.769
2.402IleGlu: 2.402 ± 1.281
1.441IlePhe: 1.441 ± 0.769
1.921IleGly: 1.921 ± 0.924
0.961IleHis: 0.961 ± 0.512
2.402IleIle: 2.402 ± 1.281
4.323IleLys: 4.323 ± 2.306
4.323IleLeu: 4.323 ± 0.902
0.961IleMet: 0.961 ± 0.618
3.362IleAsn: 3.362 ± 1.183
1.921IlePro: 1.921 ± 0.888
1.921IleGln: 1.921 ± 0.876
2.402IleArg: 2.402 ± 0.903
2.882IleSer: 2.882 ± 2.106
3.842IleThr: 3.842 ± 1.607
2.402IleVal: 2.402 ± 0.596
0.48IleTrp: 0.48 ± 0.256
2.402IleTyr: 2.402 ± 1.626
0.0IleXaa: 0.0 ± 0.0
Lys
3.842LysAla: 3.842 ± 1.069
0.961LysCys: 0.961 ± 0.512
4.803LysAsp: 4.803 ± 2.035
1.441LysGlu: 1.441 ± 0.769
2.402LysPhe: 2.402 ± 0.905
2.402LysGly: 2.402 ± 0.905
0.961LysHis: 0.961 ± 0.512
0.961LysIle: 0.961 ± 0.512
2.402LysLys: 2.402 ± 0.981
6.724LysLeu: 6.724 ± 2.367
0.48LysMet: 0.48 ± 0.256
2.402LysAsn: 2.402 ± 0.774
1.441LysPro: 1.441 ± 0.769
2.402LysGln: 2.402 ± 0.903
3.362LysArg: 3.362 ± 1.183
7.205LysSer: 7.205 ± 1.894
5.283LysThr: 5.283 ± 2.818
3.362LysVal: 3.362 ± 1.324
0.48LysTrp: 0.48 ± 0.256
1.441LysTyr: 1.441 ± 0.818
0.0LysXaa: 0.0 ± 0.0
Leu
9.126LeuAla: 9.126 ± 2.776
2.882LeuCys: 2.882 ± 1.602
8.646LeuAsp: 8.646 ± 3.534
2.882LeuGlu: 2.882 ± 0.966
5.283LeuPhe: 5.283 ± 1.189
5.283LeuGly: 5.283 ± 1.658
3.842LeuHis: 3.842 ± 2.954
4.323LeuIle: 4.323 ± 3.044
7.205LeuLys: 7.205 ± 3.843
6.724LeuLeu: 6.724 ± 1.456
0.48LeuMet: 0.48 ± 0.256
2.882LeuAsn: 2.882 ± 1.166
8.165LeuPro: 8.165 ± 2.624
3.362LeuGln: 3.362 ± 0.718
4.803LeuArg: 4.803 ± 1.32
4.323LeuSer: 4.323 ± 1.167
6.724LeuThr: 6.724 ± 1.011
5.283LeuVal: 5.283 ± 2.558
0.961LeuTrp: 0.961 ± 0.632
3.362LeuTyr: 3.362 ± 0.867
0.0LeuXaa: 0.0 ± 0.0
Met
1.441MetAla: 1.441 ± 0.769
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.48MetPhe: 0.48 ± 0.723
0.961MetGly: 0.961 ± 1.446
0.0MetHis: 0.0 ± 0.0
0.48MetIle: 0.48 ± 0.256
0.48MetLys: 0.48 ± 0.256
1.921MetLeu: 1.921 ± 1.025
0.0MetMet: 0.0 ± 0.88
0.0MetAsn: 0.0 ± 0.0
0.961MetPro: 0.961 ± 1.431
0.961MetGln: 0.961 ± 0.632
2.402MetArg: 2.402 ± 0.938
0.48MetSer: 0.48 ± 0.756
0.48MetThr: 0.48 ± 0.985
2.402MetVal: 2.402 ± 0.903
0.48MetTrp: 0.48 ± 0.256
0.48MetTyr: 0.48 ± 0.256
0.0MetXaa: 0.0 ± 0.0
Asn
3.842AsnAla: 3.842 ± 1.48
0.961AsnCys: 0.961 ± 0.618
1.921AsnAsp: 1.921 ± 1.025
2.402AsnGlu: 2.402 ± 1.281
1.441AsnPhe: 1.441 ± 0.568
1.441AsnGly: 1.441 ± 0.776
1.441AsnHis: 1.441 ± 0.639
2.402AsnIle: 2.402 ± 1.281
2.882AsnLys: 2.882 ± 1.278
3.362AsnLeu: 3.362 ± 0.738
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.842AsnPro: 3.842 ± 1.875
1.921AsnGln: 1.921 ± 0.74
2.402AsnArg: 2.402 ± 1.651
2.402AsnSer: 2.402 ± 1.075
1.921AsnThr: 1.921 ± 0.629
1.441AsnVal: 1.441 ± 0.639
0.961AsnTrp: 0.961 ± 0.632
3.362AsnTyr: 3.362 ± 1.391
0.0AsnXaa: 0.0 ± 0.0
Pro
7.685ProAla: 7.685 ± 1.913
0.0ProCys: 0.0 ± 0.0
3.842ProAsp: 3.842 ± 1.485
5.283ProGlu: 5.283 ± 2.636
1.921ProPhe: 1.921 ± 1.264
5.764ProGly: 5.764 ± 2.817
2.882ProHis: 2.882 ± 1.275
4.323ProIle: 4.323 ± 0.988
3.362ProLys: 3.362 ± 1.794
5.764ProLeu: 5.764 ± 2.697
0.961ProMet: 0.961 ± 0.632
3.362ProAsn: 3.362 ± 1.246
6.244ProPro: 6.244 ± 5.059
1.441ProGln: 1.441 ± 2.1
4.323ProArg: 4.323 ± 1.572
5.764ProSer: 5.764 ± 2.889
3.362ProThr: 3.362 ± 1.49
6.244ProVal: 6.244 ± 1.791
0.48ProTrp: 0.48 ± 0.921
1.921ProTyr: 1.921 ± 1.013
0.0ProXaa: 0.0 ± 0.0
Gln
2.882GlnAla: 2.882 ± 0.869
0.961GlnCys: 0.961 ± 0.512
2.882GlnAsp: 2.882 ± 1.537
2.402GlnGlu: 2.402 ± 1.245
1.441GlnPhe: 1.441 ± 0.639
0.48GlnGly: 0.48 ± 0.256
0.48GlnHis: 0.48 ± 0.756
0.961GlnIle: 0.961 ± 0.632
0.961GlnLys: 0.961 ± 0.512
4.323GlnLeu: 4.323 ± 0.988
0.961GlnMet: 0.961 ± 0.698
1.441GlnAsn: 1.441 ± 0.769
3.842GlnPro: 3.842 ± 2.432
0.48GlnGln: 0.48 ± 0.256
1.441GlnArg: 1.441 ± 0.769
3.362GlnSer: 3.362 ± 1.292
0.961GlnThr: 0.961 ± 0.512
2.402GlnVal: 2.402 ± 1.29
0.961GlnTrp: 0.961 ± 0.618
1.441GlnTyr: 1.441 ± 0.568
0.0GlnXaa: 0.0 ± 0.0
Arg
2.402ArgAla: 2.402 ± 0.854
1.441ArgCys: 1.441 ± 1.138
2.882ArgAsp: 2.882 ± 1.105
3.362ArgGlu: 3.362 ± 0.718
1.921ArgPhe: 1.921 ± 1.756
2.882ArgGly: 2.882 ± 0.966
0.961ArgHis: 0.961 ± 1.512
2.882ArgIle: 2.882 ± 1.033
1.441ArgLys: 1.441 ± 0.769
5.283ArgLeu: 5.283 ± 1.465
1.441ArgMet: 1.441 ± 1.053
1.441ArgAsn: 1.441 ± 0.848
4.323ArgPro: 4.323 ± 2.137
3.362ArgGln: 3.362 ± 1.292
3.362ArgArg: 3.362 ± 2.062
3.842ArgSer: 3.842 ± 2.206
3.362ArgThr: 3.362 ± 0.718
4.803ArgVal: 4.803 ± 1.118
0.48ArgTrp: 0.48 ± 0.256
1.921ArgTyr: 1.921 ± 1.025
0.0ArgXaa: 0.0 ± 0.0
Ser
4.323SerAla: 4.323 ± 3.653
1.921SerCys: 1.921 ± 1.65
2.882SerAsp: 2.882 ± 0.941
1.441SerGlu: 1.441 ± 0.568
4.323SerPhe: 4.323 ± 1.205
4.323SerGly: 4.323 ± 2.777
2.402SerHis: 2.402 ± 1.159
3.842SerIle: 3.842 ± 2.133
3.362SerLys: 3.362 ± 0.718
8.165SerLeu: 8.165 ± 2.026
0.961SerMet: 0.961 ± 0.878
5.283SerAsn: 5.283 ± 2.436
3.362SerPro: 3.362 ± 1.964
3.842SerGln: 3.842 ± 1.555
4.803SerArg: 4.803 ± 1.088
6.244SerSer: 6.244 ± 4.455
3.362SerThr: 3.362 ± 2.514
6.244SerVal: 6.244 ± 2.311
0.48SerTrp: 0.48 ± 0.921
0.961SerTyr: 0.961 ± 0.512
0.0SerXaa: 0.0 ± 0.0
Thr
5.283ThrAla: 5.283 ± 1.996
1.441ThrCys: 1.441 ± 0.776
2.402ThrAsp: 2.402 ± 0.774
1.921ThrGlu: 1.921 ± 1.025
4.323ThrPhe: 4.323 ± 1.651
1.921ThrGly: 1.921 ± 1.013
3.362ThrHis: 3.362 ± 0.943
2.882ThrIle: 2.882 ± 0.819
4.803ThrLys: 4.803 ± 1.705
4.803ThrLeu: 4.803 ± 1.705
0.48ThrMet: 0.48 ± 0.256
1.441ThrAsn: 1.441 ± 0.568
9.606ThrPro: 9.606 ± 3.204
1.441ThrGln: 1.441 ± 0.769
3.362ThrArg: 3.362 ± 0.738
1.921ThrSer: 1.921 ± 0.629
2.882ThrThr: 2.882 ± 2.34
3.842ThrVal: 3.842 ± 1.014
0.48ThrTrp: 0.48 ± 0.256
2.402ThrTyr: 2.402 ± 0.796
0.0ThrXaa: 0.0 ± 0.0
Val
7.205ValAla: 7.205 ± 2.795
1.441ValCys: 1.441 ± 2.222
2.402ValAsp: 2.402 ± 0.774
5.764ValGlu: 5.764 ± 1.767
1.441ValPhe: 1.441 ± 0.769
4.323ValGly: 4.323 ± 1.922
2.882ValHis: 2.882 ± 1.275
3.842ValIle: 3.842 ± 1.413
3.842ValLys: 3.842 ± 1.413
6.724ValLeu: 6.724 ± 2.074
0.961ValMet: 0.961 ± 0.512
3.842ValAsn: 3.842 ± 1.606
3.842ValPro: 3.842 ± 1.162
2.882ValGln: 2.882 ± 1.136
1.921ValArg: 1.921 ± 1.264
2.882ValSer: 2.882 ± 2.021
2.402ValThr: 2.402 ± 1.281
4.803ValVal: 4.803 ± 0.792
0.961ValTrp: 0.961 ± 0.632
2.402ValTyr: 2.402 ± 0.774
0.0ValXaa: 0.0 ± 0.0
Trp
1.921TrpAla: 1.921 ± 1.025
0.0TrpCys: 0.0 ± 0.0
0.48TrpAsp: 0.48 ± 0.256
0.48TrpGlu: 0.48 ± 0.256
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.48TrpIle: 0.48 ± 0.256
0.48TrpLys: 0.48 ± 0.256
0.48TrpLeu: 0.48 ± 0.256
0.961TrpMet: 0.961 ± 0.689
0.961TrpAsn: 0.961 ± 0.632
0.961TrpPro: 0.961 ± 0.618
0.48TrpGln: 0.48 ± 0.256
0.961TrpArg: 0.961 ± 0.632
0.48TrpSer: 0.48 ± 0.723
1.921TrpThr: 1.921 ± 0.629
2.402TrpVal: 2.402 ± 0.938
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.323TyrAla: 4.323 ± 1.614
0.48TyrCys: 0.48 ± 0.256
1.441TyrAsp: 1.441 ± 0.639
0.961TyrGlu: 0.961 ± 0.618
0.48TyrPhe: 0.48 ± 0.256
3.362TyrGly: 3.362 ± 1.391
0.961TyrHis: 0.961 ± 0.512
0.961TyrIle: 0.961 ± 0.512
0.48TyrLys: 0.48 ± 0.256
1.441TyrLeu: 1.441 ± 0.769
0.48TyrMet: 0.48 ± 0.256
0.48TyrAsn: 0.48 ± 0.256
1.921TyrPro: 1.921 ± 0.629
0.961TyrGln: 0.961 ± 0.618
2.882TyrArg: 2.882 ± 1.539
4.323TyrSer: 4.323 ± 1.669
2.402TyrThr: 2.402 ± 1.567
3.842TyrVal: 3.842 ± 1.196
0.48TyrTrp: 0.48 ± 0.256
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2083 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski