Amino acid dipepetide frequency for Phaseolus vulgaris (Kidney bean) (French bean)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.713AlaAla: 5.713 ± 0.032	1.23AlaCys: 1.23 ± 0.012	2.86AlaAsp: 2.86 ± 0.015	3.987AlaGlu: 3.987 ± 0.02	2.756AlaPhe: 2.756 ± 0.018	3.682AlaGly: 3.682 ± 0.019	1.306AlaHis: 1.306 ± 0.01	3.651AlaIle: 3.651 ± 0.018	3.802AlaLys: 3.802 ± 0.02	6.465AlaLeu: 6.465 ± 0.028	1.666AlaMet: 1.666 ± 0.012	2.566AlaAsn: 2.566 ± 0.013	2.698AlaPro: 2.698 ± 0.02	2.064AlaGln: 2.064 ± 0.015	3.173AlaArg: 3.173 ± 0.018	5.863AlaSer: 5.863 ± 0.025	3.583AlaThr: 3.583 ± 0.018	4.629AlaVal: 4.629 ± 0.021	0.746AlaTrp: 0.746 ± 0.008	1.75AlaTyr: 1.75 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.022CysAla: 1.022 ± 0.009	0.563CysCys: 0.563 ± 0.008	0.915CysAsp: 0.915 ± 0.01	0.943CysGlu: 0.943 ± 0.009	0.984CysPhe: 0.984 ± 0.01	1.414CysGly: 1.414 ± 0.014	0.517CysHis: 0.517 ± 0.008	1.024CysIle: 1.024 ± 0.009	1.165CysLys: 1.165 ± 0.011	1.906CysLeu: 1.906 ± 0.014	0.466CysMet: 0.466 ± 0.006	0.897CysAsn: 0.897 ± 0.008	0.962CysPro: 0.962 ± 0.011	0.63CysGln: 0.63 ± 0.007	1.016CysArg: 1.016 ± 0.01	1.897CysSer: 1.897 ± 0.013	0.889CysThr: 0.889 ± 0.009	1.152CysVal: 1.152 ± 0.009	0.25CysTrp: 0.25 ± 0.004	0.562CysTyr: 0.562 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	3.336AspAla: 3.336 ± 0.018	0.987AspCys: 0.987 ± 0.011	3.486AspAsp: 3.486 ± 0.023	3.857AspGlu: 3.857 ± 0.019	2.362AspPhe: 2.362 ± 0.015	3.589AspGly: 3.589 ± 0.018	1.247AspHis: 1.247 ± 0.01	3.065AspIle: 3.065 ± 0.018	2.772AspLys: 2.772 ± 0.017	5.024AspLeu: 5.024 ± 0.023	1.299AspMet: 1.299 ± 0.01	2.198AspAsn: 2.198 ± 0.015	2.508AspPro: 2.508 ± 0.017	1.701AspGln: 1.701 ± 0.012	2.227AspArg: 2.227 ± 0.014	4.318AspSer: 4.318 ± 0.022	2.309AspThr: 2.309 ± 0.014	3.61AspVal: 3.61 ± 0.019	0.686AspTrp: 0.686 ± 0.008	1.54AspTyr: 1.54 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.533GluAla: 4.533 ± 0.022	0.994GluCys: 0.994 ± 0.009	3.989GluAsp: 3.989 ± 0.022	6.301GluGlu: 6.301 ± 0.034	2.418GluPhe: 2.418 ± 0.012	3.794GluGly: 3.794 ± 0.018	1.316GluHis: 1.316 ± 0.012	3.786GluIle: 3.786 ± 0.019	4.867GluLys: 4.867 ± 0.028	5.843GluLeu: 5.843 ± 0.03	1.724GluMet: 1.724 ± 0.013	3.281GluAsn: 3.281 ± 0.02	2.03GluPro: 2.03 ± 0.015	2.142GluGln: 2.142 ± 0.016	3.317GluArg: 3.317 ± 0.022	4.644GluSer: 4.644 ± 0.021	3.01GluThr: 3.01 ± 0.017	4.222GluVal: 4.222 ± 0.02	0.772GluTrp: 0.772 ± 0.009	1.673GluTyr: 1.673 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	2.475PheAla: 2.475 ± 0.016	0.973PheCys: 0.973 ± 0.01	2.376PheAsp: 2.376 ± 0.015	2.351PheGlu: 2.351 ± 0.013	2.103PhePhe: 2.103 ± 0.014	3.147PheGly: 3.147 ± 0.021	1.234PheHis: 1.234 ± 0.011	2.155PheIle: 2.155 ± 0.016	2.156PheLys: 2.156 ± 0.013	4.468PheLeu: 4.468 ± 0.024	0.973PheMet: 0.973 ± 0.009	1.905PheAsn: 1.905 ± 0.013	2.241PhePro: 2.241 ± 0.016	1.615PheGln: 1.615 ± 0.011	2.057PheArg: 2.057 ± 0.014	4.326PheSer: 4.326 ± 0.022	2.088PheThr: 2.088 ± 0.013	2.846PheVal: 2.846 ± 0.017	0.576PheTrp: 0.576 ± 0.007	1.302PheTyr: 1.302 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	3.682GlyAla: 3.682 ± 0.022	1.325GlyCys: 1.325 ± 0.012	3.239GlyAsp: 3.239 ± 0.018	3.657GlyGlu: 3.657 ± 0.019	3.126GlyPhe: 3.126 ± 0.019	5.141GlyGly: 5.141 ± 0.047	1.54GlyHis: 1.54 ± 0.012	3.552GlyIle: 3.552 ± 0.018	4.118GlyLys: 4.118 ± 0.02	5.778GlyLeu: 5.778 ± 0.025	1.476GlyMet: 1.476 ± 0.011	3.177GlyAsn: 3.177 ± 0.021	2.283GlyPro: 2.283 ± 0.015	1.959GlyGln: 1.959 ± 0.014	3.462GlyArg: 3.462 ± 0.021	5.876GlySer: 5.876 ± 0.03	3.253GlyThr: 3.253 ± 0.016	4.271GlyVal: 4.271 ± 0.021	0.882GlyTrp: 0.882 ± 0.01	2.045GlyTyr: 2.045 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.532HisAla: 1.532 ± 0.012	0.56HisCys: 0.56 ± 0.007	1.224HisAsp: 1.224 ± 0.01	1.315HisGlu: 1.315 ± 0.011	1.162HisPhe: 1.162 ± 0.011	1.736HisGly: 1.736 ± 0.013	1.089HisHis: 1.089 ± 0.014	1.269HisIle: 1.269 ± 0.01	1.28HisLys: 1.28 ± 0.01	2.559HisLeu: 2.559 ± 0.015	0.578HisMet: 0.578 ± 0.007	1.125HisAsn: 1.125 ± 0.011	1.418HisPro: 1.418 ± 0.014	1.068HisGln: 1.068 ± 0.01	1.4HisArg: 1.4 ± 0.01	2.181HisSer: 2.181 ± 0.014	1.111HisThr: 1.111 ± 0.01	1.686HisVal: 1.686 ± 0.011	0.31HisTrp: 0.31 ± 0.005	0.746HisTyr: 0.746 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.472IleAla: 3.472 ± 0.017	1.111IleCys: 1.111 ± 0.01	2.857IleAsp: 2.857 ± 0.016	3.185IleGlu: 3.185 ± 0.018	2.34IlePhe: 2.34 ± 0.015	3.413IleGly: 3.413 ± 0.017	1.388IleHis: 1.388 ± 0.01	2.926IleIle: 2.926 ± 0.018	2.958IleLys: 2.958 ± 0.017	5.337IleLeu: 5.337 ± 0.024	1.164IleMet: 1.164 ± 0.01	2.29IleAsn: 2.29 ± 0.014	3.01IlePro: 3.01 ± 0.021	2.036IleGln: 2.036 ± 0.014	2.576IleArg: 2.576 ± 0.016	4.879IleSer: 4.879 ± 0.02	2.713IleThr: 2.713 ± 0.015	3.538IleVal: 3.538 ± 0.018	0.706IleTrp: 0.706 ± 0.009	1.499IleTyr: 1.499 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.846LysAla: 3.846 ± 0.02	1.047LysCys: 1.047 ± 0.011	3.258LysAsp: 3.258 ± 0.019	4.807LysGlu: 4.807 ± 0.027	2.253LysPhe: 2.253 ± 0.015	3.805LysGly: 3.805 ± 0.018	1.478LysHis: 1.478 ± 0.01	3.352LysIle: 3.352 ± 0.017	4.694LysLys: 4.694 ± 0.024	6.107LysLeu: 6.107 ± 0.03	1.522LysMet: 1.522 ± 0.011	2.812LysAsn: 2.812 ± 0.019	2.71LysPro: 2.71 ± 0.017	2.288LysGln: 2.288 ± 0.015	3.605LysArg: 3.605 ± 0.023	4.749LysSer: 4.749 ± 0.023	3.003LysThr: 3.003 ± 0.018	4.012LysVal: 4.012 ± 0.022	0.827LysTrp: 0.827 ± 0.009	1.628LysTyr: 1.628 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.245LeuAla: 6.245 ± 0.028	1.935LeuCys: 1.935 ± 0.012	5.095LeuAsp: 5.095 ± 0.019	6.33LeuGlu: 6.33 ± 0.029	4.044LeuPhe: 4.044 ± 0.021	5.684LeuGly: 5.684 ± 0.028	2.842LeuHis: 2.842 ± 0.018	4.584LeuIle: 4.584 ± 0.019	6.396LeuLys: 6.396 ± 0.031	10.147LeuLeu: 10.147 ± 0.038	2.081LeuMet: 2.081 ± 0.012	4.217LeuAsn: 4.217 ± 0.021	5.213LeuPro: 5.213 ± 0.026	4.432LeuGln: 4.432 ± 0.022	5.328LeuArg: 5.328 ± 0.025	9.037LeuSer: 9.037 ± 0.034	4.586LeuThr: 4.586 ± 0.021	6.389LeuVal: 6.389 ± 0.026	1.174LeuTrp: 1.174 ± 0.011	2.562LeuTyr: 2.562 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	1.983MetAla: 1.983 ± 0.014	0.33MetCys: 0.33 ± 0.005	1.396MetAsp: 1.396 ± 0.01	1.951MetGlu: 1.951 ± 0.014	0.848MetPhe: 0.848 ± 0.009	1.573MetGly: 1.573 ± 0.012	0.585MetHis: 0.585 ± 0.007	1.173MetIle: 1.173 ± 0.01	1.687MetLys: 1.687 ± 0.011	2.205MetLeu: 2.205 ± 0.014	0.663MetMet: 0.663 ± 0.007	1.077MetAsn: 1.077 ± 0.01	1.016MetPro: 1.016 ± 0.009	0.955MetGln: 0.955 ± 0.011	1.157MetArg: 1.157 ± 0.009	1.782MetSer: 1.782 ± 0.013	1.035MetThr: 1.035 ± 0.008	1.633MetVal: 1.633 ± 0.011	0.272MetTrp: 0.272 ± 0.004	0.572MetTyr: 0.572 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.742AsnAla: 2.742 ± 0.017	0.928AsnCys: 0.928 ± 0.01	2.202AsnAsp: 2.202 ± 0.015	2.661AsnGlu: 2.661 ± 0.017	2.112AsnPhe: 2.112 ± 0.013	3.252AsnGly: 3.252 ± 0.016	1.251AsnHis: 1.251 ± 0.011	2.71AsnIle: 2.71 ± 0.015	2.566AsnLys: 2.566 ± 0.016	4.966AsnLeu: 4.966 ± 0.033	1.205AsnMet: 1.205 ± 0.01	2.591AsnAsn: 2.591 ± 0.022	2.333AsnPro: 2.333 ± 0.013	1.76AsnGln: 1.76 ± 0.014	2.01AsnArg: 2.01 ± 0.014	4.156AsnSer: 4.156 ± 0.019	2.182AsnThr: 2.182 ± 0.015	2.937AsnVal: 2.937 ± 0.016	0.593AsnTrp: 0.593 ± 0.007	1.357AsnTyr: 1.357 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	2.735ProAla: 2.735 ± 0.018	0.8ProCys: 0.8 ± 0.009	2.308ProAsp: 2.308 ± 0.015	2.948ProGlu: 2.948 ± 0.016	2.134ProPhe: 2.134 ± 0.013	2.507ProGly: 2.507 ± 0.017	1.236ProHis: 1.236 ± 0.012	2.302ProIle: 2.302 ± 0.015	2.796ProLys: 2.796 ± 0.017	4.458ProLeu: 4.458 ± 0.02	0.926ProMet: 0.926 ± 0.009	2.44ProAsn: 2.44 ± 0.015	3.813ProPro: 3.813 ± 0.06	1.891ProGln: 1.891 ± 0.017	2.272ProArg: 2.272 ± 0.015	5.273ProSer: 5.273 ± 0.025	2.635ProThr: 2.635 ± 0.017	2.935ProVal: 2.935 ± 0.019	0.571ProTrp: 0.571 ± 0.007	1.315ProTyr: 1.315 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	2.195GlnAla: 2.195 ± 0.015	0.635GlnCys: 0.635 ± 0.008	1.668GlnAsp: 1.668 ± 0.012	2.395GlnGlu: 2.395 ± 0.018	1.409GlnPhe: 1.409 ± 0.01	2.088GlnGly: 2.088 ± 0.014	1.043GlnHis: 1.043 ± 0.011	2.064GlnIle: 2.064 ± 0.014	2.398GlnLys: 2.398 ± 0.015	3.702GlnLeu: 3.702 ± 0.019	0.967GlnMet: 0.967 ± 0.009	1.958GlnAsn: 1.958 ± 0.015	1.77GlnPro: 1.77 ± 0.015	2.036GlnGln: 2.036 ± 0.026	2.057GlnArg: 2.057 ± 0.014	2.868GlnSer: 2.868 ± 0.015	1.833GlnThr: 1.833 ± 0.014	2.289GlnVal: 2.289 ± 0.014	0.464GlnTrp: 0.464 ± 0.006	0.956GlnTyr: 0.956 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	2.977ArgAla: 2.977 ± 0.017	0.961ArgCys: 0.961 ± 0.01	2.616ArgAsp: 2.616 ± 0.017	3.271ArgGlu: 3.271 ± 0.021	2.19ArgPhe: 2.19 ± 0.012	3.068ArgGly: 3.068 ± 0.018	1.304ArgHis: 1.304 ± 0.011	2.79ArgIle: 2.79 ± 0.014	3.773ArgLys: 3.773 ± 0.02	4.793ArgLeu: 4.793 ± 0.025	1.268ArgMet: 1.268 ± 0.01	2.49ArgAsn: 2.49 ± 0.015	2.133ArgPro: 2.133 ± 0.013	1.747ArgGln: 1.747 ± 0.013	3.62ArgArg: 3.62 ± 0.023	4.176ArgSer: 4.176 ± 0.023	2.435ArgThr: 2.435 ± 0.015	3.345ArgVal: 3.345 ± 0.016	0.728ArgTrp: 0.728 ± 0.009	1.41ArgTyr: 1.41 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.198SerAla: 5.198 ± 0.024	1.75SerCys: 1.75 ± 0.015	4.488SerAsp: 4.488 ± 0.023	5.013SerGlu: 5.013 ± 0.025	4.198SerPhe: 4.198 ± 0.022	5.84SerGly: 5.84 ± 0.028	2.231SerHis: 2.231 ± 0.014	4.601SerIle: 4.601 ± 0.023	5.061SerLys: 5.061 ± 0.024	9.051SerLeu: 9.051 ± 0.038	2.119SerMet: 2.119 ± 0.013	4.401SerAsn: 4.401 ± 0.02	4.523SerPro: 4.523 ± 0.034	3.111SerGln: 3.111 ± 0.019	4.237SerArg: 4.237 ± 0.024	10.944SerSer: 10.944 ± 0.048	4.73SerThr: 4.73 ± 0.023	5.453SerVal: 5.453 ± 0.023	1.19SerTrp: 1.19 ± 0.012	2.404SerTyr: 2.404 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	3.238ThrAla: 3.238 ± 0.017	0.958ThrCys: 0.958 ± 0.01	2.238ThrAsp: 2.238 ± 0.014	2.794ThrGlu: 2.794 ± 0.016	2.21ThrPhe: 2.21 ± 0.014	3.081ThrGly: 3.081 ± 0.018	1.154ThrHis: 1.154 ± 0.009	2.802ThrIle: 2.802 ± 0.015	2.822ThrLys: 2.822 ± 0.017	5.077ThrLeu: 5.077 ± 0.021	1.199ThrMet: 1.199 ± 0.008	2.297ThrAsn: 2.297 ± 0.014	2.673ThrPro: 2.673 ± 0.018	1.65ThrGln: 1.65 ± 0.011	2.347ThrArg: 2.347 ± 0.014	4.661ThrSer: 4.661 ± 0.02	3.154ThrThr: 3.154 ± 0.022	3.414ThrVal: 3.414 ± 0.018	0.645ThrTrp: 0.645 ± 0.007	1.4ThrTyr: 1.4 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.776ValAla: 4.776 ± 0.021	1.191ValCys: 1.191 ± 0.01	3.68ValAsp: 3.68 ± 0.019	4.483ValGlu: 4.483 ± 0.021	2.836ValPhe: 2.836 ± 0.018	4.186ValGly: 4.186 ± 0.021	1.563ValHis: 1.563 ± 0.012	3.402ValIle: 3.402 ± 0.017	3.964ValLys: 3.964 ± 0.019	6.403ValLeu: 6.403 ± 0.027	1.512ValMet: 1.512 ± 0.012	2.699ValAsn: 2.699 ± 0.016	3.203ValPro: 3.203 ± 0.019	2.354ValGln: 2.354 ± 0.014	3.057ValArg: 3.057 ± 0.015	5.609ValSer: 5.609 ± 0.022	3.328ValThr: 3.328 ± 0.016	5.067ValVal: 5.067 ± 0.024	0.79ValTrp: 0.79 ± 0.009	1.941ValTyr: 1.941 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.711TrpAla: 0.711 ± 0.008	0.253TrpCys: 0.253 ± 0.004	0.679TrpAsp: 0.679 ± 0.007	0.779TrpGlu: 0.779 ± 0.009	0.575TrpPhe: 0.575 ± 0.007	0.738TrpGly: 0.738 ± 0.009	0.295TrpHis: 0.295 ± 0.004	0.718TrpIle: 0.718 ± 0.007	0.977TrpLys: 0.977 ± 0.008	1.261TrpLeu: 1.261 ± 0.011	0.347TrpMet: 0.347 ± 0.006	0.759TrpAsn: 0.759 ± 0.008	0.488TrpPro: 0.488 ± 0.007	0.43TrpGln: 0.43 ± 0.007	0.783TrpArg: 0.783 ± 0.008	1.006TrpSer: 1.006 ± 0.01	0.633TrpThr: 0.633 ± 0.007	0.808TrpVal: 0.808 ± 0.008	0.246TrpTrp: 0.246 ± 0.005	0.338TrpTyr: 0.338 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.779TyrAla: 1.779 ± 0.014	0.643TyrCys: 0.643 ± 0.007	1.547TyrAsp: 1.547 ± 0.012	1.626TyrGlu: 1.626 ± 0.01	1.307TyrPhe: 1.307 ± 0.012	2.106TyrGly: 2.106 ± 0.016	0.731TyrHis: 0.731 ± 0.009	1.474TyrIle: 1.474 ± 0.011	1.55TyrLys: 1.55 ± 0.011	2.769TyrLeu: 2.769 ± 0.017	0.739TyrMet: 0.739 ± 0.009	1.336TyrAsn: 1.336 ± 0.011	1.27TyrPro: 1.27 ± 0.012	0.926TyrGln: 0.926 ± 0.009	1.392TyrArg: 1.392 ± 0.012	2.3TyrSer: 2.3 ± 0.017	1.305TyrThr: 1.305 ± 0.012	1.804TyrVal: 1.804 ± 0.013	0.395TyrTrp: 0.395 ± 0.005	0.982TyrTyr: 0.982 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 30501 proteins (12704981 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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