Amino acid dipepetide frequency for Catonella morbi ATCC 51271

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.483AlaAla: 5.483 ± 0.105	0.838AlaCys: 0.838 ± 0.031	4.213AlaAsp: 4.213 ± 0.071	5.378AlaGlu: 5.378 ± 0.073	2.972AlaPhe: 2.972 ± 0.059	5.359AlaGly: 5.359 ± 0.081	0.854AlaHis: 0.854 ± 0.034	5.077AlaIle: 5.077 ± 0.081	5.609AlaLys: 5.609 ± 0.089	6.03AlaLeu: 6.03 ± 0.087	1.943AlaMet: 1.943 ± 0.052	2.798AlaAsn: 2.798 ± 0.057	1.564AlaPro: 1.564 ± 0.041	1.304AlaGln: 1.304 ± 0.04	2.508AlaArg: 2.508 ± 0.056	3.56AlaSer: 3.56 ± 0.067	3.089AlaThr: 3.089 ± 0.062	5.558AlaVal: 5.558 ± 0.079	0.506AlaTrp: 0.506 ± 0.025	2.553AlaTyr: 2.553 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.655CysAla: 0.655 ± 0.026	0.185CysCys: 0.185 ± 0.014	0.677CysAsp: 0.677 ± 0.029	0.8CysGlu: 0.8 ± 0.032	0.549CysPhe: 0.549 ± 0.023	1.083CysGly: 1.083 ± 0.032	0.223CysHis: 0.223 ± 0.015	0.942CysIle: 0.942 ± 0.028	0.897CysLys: 0.897 ± 0.029	0.993CysLeu: 0.993 ± 0.034	0.341CysMet: 0.341 ± 0.019	0.56CysAsn: 0.56 ± 0.021	0.441CysPro: 0.441 ± 0.024	0.229CysGln: 0.229 ± 0.014	0.465CysArg: 0.465 ± 0.024	0.692CysSer: 0.692 ± 0.027	0.533CysThr: 0.533 ± 0.022	0.721CysVal: 0.721 ± 0.027	0.089CysTrp: 0.089 ± 0.009	0.457CysTyr: 0.457 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.212AspAla: 3.212 ± 0.055	0.63AspCys: 0.63 ± 0.027	3.0AspAsp: 3.0 ± 0.066	5.221AspGlu: 5.221 ± 0.074	3.053AspPhe: 3.053 ± 0.052	4.138AspGly: 4.138 ± 0.077	0.547AspHis: 0.547 ± 0.029	5.512AspIle: 5.512 ± 0.074	5.305AspLys: 5.305 ± 0.083	4.092AspLeu: 4.092 ± 0.064	1.671AspMet: 1.671 ± 0.041	2.976AspAsn: 2.976 ± 0.06	1.15AspPro: 1.15 ± 0.039	0.661AspGln: 0.661 ± 0.025	2.259AspArg: 2.259 ± 0.046	3.201AspSer: 3.201 ± 0.054	2.914AspThr: 2.914 ± 0.069	3.64AspVal: 3.64 ± 0.067	0.555AspTrp: 0.555 ± 0.027	2.791AspTyr: 2.791 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	5.504GluAla: 5.504 ± 0.09	0.644GluCys: 0.644 ± 0.025	4.241GluAsp: 4.241 ± 0.07	7.066GluGlu: 7.066 ± 0.106	3.167GluPhe: 3.167 ± 0.055	4.521GluGly: 4.521 ± 0.074	1.069GluHis: 1.069 ± 0.034	6.548GluIle: 6.548 ± 0.087	7.719GluLys: 7.719 ± 0.091	7.438GluLeu: 7.438 ± 0.092	2.204GluMet: 2.204 ± 0.044	5.224GluAsn: 5.224 ± 0.08	1.765GluPro: 1.765 ± 0.041	1.896GluGln: 1.896 ± 0.04	2.975GluArg: 2.975 ± 0.064	3.544GluSer: 3.544 ± 0.059	3.586GluThr: 3.586 ± 0.06	4.813GluVal: 4.813 ± 0.08	0.58GluTrp: 0.58 ± 0.022	3.37GluTyr: 3.37 ± 0.06	0.0GluXaa: 0.0 ± 0.0
Phe	3.004PheAla: 3.004 ± 0.055	0.617PheCys: 0.617 ± 0.025	2.851PheAsp: 2.851 ± 0.052	3.131PheGlu: 3.131 ± 0.063	2.089PhePhe: 2.089 ± 0.057	3.075PheGly: 3.075 ± 0.063	0.639PheHis: 0.639 ± 0.022	3.775PheIle: 3.775 ± 0.062	3.08PheLys: 3.08 ± 0.056	3.992PheLeu: 3.992 ± 0.082	1.286PheMet: 1.286 ± 0.038	2.365PheAsn: 2.365 ± 0.055	1.348PhePro: 1.348 ± 0.04	0.887PheGln: 0.887 ± 0.034	1.631PheArg: 1.631 ± 0.038	3.321PheSer: 3.321 ± 0.058	2.661PheThr: 2.661 ± 0.062	3.029PheVal: 3.029 ± 0.056	0.437PheTrp: 0.437 ± 0.022	1.862PheTyr: 1.862 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.287GlyAla: 4.287 ± 0.078	0.872GlyCys: 0.872 ± 0.034	3.409GlyAsp: 3.409 ± 0.062	4.859GlyGlu: 4.859 ± 0.085	3.263GlyPhe: 3.263 ± 0.062	4.721GlyGly: 4.721 ± 0.092	1.038GlyHis: 1.038 ± 0.031	6.337GlyIle: 6.337 ± 0.091	6.508GlyLys: 6.508 ± 0.095	5.809GlyLeu: 5.809 ± 0.08	2.059GlyMet: 2.059 ± 0.051	3.549GlyAsn: 3.549 ± 0.073	0.995GlyPro: 0.995 ± 0.035	1.543GlyGln: 1.543 ± 0.042	2.85GlyArg: 2.85 ± 0.054	4.108GlySer: 4.108 ± 0.062	3.606GlyThr: 3.606 ± 0.071	4.605GlyVal: 4.605 ± 0.067	0.568GlyTrp: 0.568 ± 0.028	3.202GlyTyr: 3.202 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	0.729HisAla: 0.729 ± 0.028	0.196HisCys: 0.196 ± 0.015	0.688HisAsp: 0.688 ± 0.028	0.823HisGlu: 0.823 ± 0.028	0.794HisPhe: 0.794 ± 0.029	0.944HisGly: 0.944 ± 0.031	0.279HisHis: 0.279 ± 0.02	1.339HisIle: 1.339 ± 0.038	1.026HisLys: 1.026 ± 0.031	1.209HisLeu: 1.209 ± 0.033	0.344HisMet: 0.344 ± 0.019	0.768HisAsn: 0.768 ± 0.027	0.635HisPro: 0.635 ± 0.025	0.346HisGln: 0.346 ± 0.022	0.684HisArg: 0.684 ± 0.025	0.874HisSer: 0.874 ± 0.028	0.73HisThr: 0.73 ± 0.025	0.687HisVal: 0.687 ± 0.028	0.122HisTrp: 0.122 ± 0.01	0.67HisTyr: 0.67 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.733IleAla: 5.733 ± 0.078	1.178IleCys: 1.178 ± 0.033	4.486IleAsp: 4.486 ± 0.076	5.757IleGlu: 5.757 ± 0.079	3.788IlePhe: 3.788 ± 0.062	5.214IleGly: 5.214 ± 0.08	1.125IleHis: 1.125 ± 0.033	7.078IleIle: 7.078 ± 0.117	6.776IleLys: 6.776 ± 0.082	7.453IleLeu: 7.453 ± 0.108	2.288IleMet: 2.288 ± 0.05	4.162IleAsn: 4.162 ± 0.065	3.203IlePro: 3.203 ± 0.062	1.727IleGln: 1.727 ± 0.043	3.364IleArg: 3.364 ± 0.062	6.049IleSer: 6.049 ± 0.076	4.709IleThr: 4.709 ± 0.065	5.15IleVal: 5.15 ± 0.074	0.587IleTrp: 0.587 ± 0.025	3.176IleTyr: 3.176 ± 0.06	0.0IleXaa: 0.0 ± 0.0
Lys	5.839LysAla: 5.839 ± 0.087	0.708LysCys: 0.708 ± 0.026	5.008LysAsp: 5.008 ± 0.079	8.194LysGlu: 8.194 ± 0.098	2.945LysPhe: 2.945 ± 0.054	5.148LysGly: 5.148 ± 0.075	1.086LysHis: 1.086 ± 0.036	6.608LysIle: 6.608 ± 0.078	8.052LysLys: 8.052 ± 0.111	7.573LysLeu: 7.573 ± 0.088	2.482LysMet: 2.482 ± 0.049	5.304LysAsn: 5.304 ± 0.08	2.307LysPro: 2.307 ± 0.049	2.183LysGln: 2.183 ± 0.049	3.255LysArg: 3.255 ± 0.054	4.731LysSer: 4.731 ± 0.076	4.62LysThr: 4.62 ± 0.076	5.194LysVal: 5.194 ± 0.082	0.73LysTrp: 0.73 ± 0.031	3.88LysTyr: 3.88 ± 0.08	0.0LysXaa: 0.0 ± 0.0
Leu	6.143LeuAla: 6.143 ± 0.088	1.163LeuCys: 1.163 ± 0.041	4.743LeuAsp: 4.743 ± 0.08	6.027LeuGlu: 6.027 ± 0.083	3.914LeuPhe: 3.914 ± 0.077	5.625LeuGly: 5.625 ± 0.084	1.263LeuHis: 1.263 ± 0.039	7.207LeuIle: 7.207 ± 0.105	7.486LeuLys: 7.486 ± 0.075	7.937LeuLeu: 7.937 ± 0.125	2.509LeuMet: 2.509 ± 0.045	4.576LeuAsn: 4.576 ± 0.067	3.323LeuPro: 3.323 ± 0.06	2.053LeuGln: 2.053 ± 0.044	3.475LeuArg: 3.475 ± 0.07	6.983LeuSer: 6.983 ± 0.083	5.061LeuThr: 5.061 ± 0.076	5.253LeuVal: 5.253 ± 0.081	0.714LeuTrp: 0.714 ± 0.027	3.405LeuTyr: 3.405 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	2.114MetAla: 2.114 ± 0.049	0.278MetCys: 0.278 ± 0.014	1.62MetAsp: 1.62 ± 0.04	2.132MetGlu: 2.132 ± 0.051	1.073MetPhe: 1.073 ± 0.036	1.943MetGly: 1.943 ± 0.048	0.407MetHis: 0.407 ± 0.019	2.096MetIle: 2.096 ± 0.046	2.755MetLys: 2.755 ± 0.059	2.484MetLeu: 2.484 ± 0.053	0.852MetMet: 0.852 ± 0.037	1.499MetAsn: 1.499 ± 0.035	1.036MetPro: 1.036 ± 0.03	0.827MetGln: 0.827 ± 0.028	1.038MetArg: 1.038 ± 0.027	1.8MetSer: 1.8 ± 0.041	1.412MetThr: 1.412 ± 0.033	1.761MetVal: 1.761 ± 0.044	0.218MetTrp: 0.218 ± 0.016	0.899MetTyr: 0.899 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.21AsnAla: 3.21 ± 0.055	0.572AsnCys: 0.572 ± 0.024	2.725AsnAsp: 2.725 ± 0.064	3.999AsnGlu: 3.999 ± 0.065	2.272AsnPhe: 2.272 ± 0.047	3.729AsnGly: 3.729 ± 0.066	0.715AsnHis: 0.715 ± 0.028	4.77AsnIle: 4.77 ± 0.077	4.52AsnLys: 4.52 ± 0.077	4.567AsnLeu: 4.567 ± 0.064	1.507AsnMet: 1.507 ± 0.04	2.871AsnAsn: 2.871 ± 0.068	2.072AsnPro: 2.072 ± 0.043	1.244AsnGln: 1.244 ± 0.032	2.077AsnArg: 2.077 ± 0.047	3.14AsnSer: 3.14 ± 0.057	2.769AsnThr: 2.769 ± 0.055	3.14AsnVal: 3.14 ± 0.058	0.458AsnTrp: 0.458 ± 0.023	2.355AsnTyr: 2.355 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	1.926ProAla: 1.926 ± 0.05	0.303ProCys: 0.303 ± 0.018	2.049ProAsp: 2.049 ± 0.047	2.893ProGlu: 2.893 ± 0.059	1.483ProPhe: 1.483 ± 0.034	1.741ProGly: 1.741 ± 0.049	0.465ProHis: 0.465 ± 0.022	2.102ProIle: 2.102 ± 0.051	2.18ProLys: 2.18 ± 0.051	2.569ProLeu: 2.569 ± 0.055	0.771ProMet: 0.771 ± 0.03	1.367ProAsn: 1.367 ± 0.039	0.604ProPro: 0.604 ± 0.027	0.795ProGln: 0.795 ± 0.028	0.802ProArg: 0.802 ± 0.028	1.626ProSer: 1.626 ± 0.032	1.478ProThr: 1.478 ± 0.045	2.541ProVal: 2.541 ± 0.055	0.27ProTrp: 0.27 ± 0.016	1.344ProTyr: 1.344 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	1.69GlnAla: 1.69 ± 0.044	0.237GlnCys: 0.237 ± 0.014	1.088GlnAsp: 1.088 ± 0.033	1.541GlnGlu: 1.541 ± 0.041	0.979GlnPhe: 0.979 ± 0.03	1.471GlnGly: 1.471 ± 0.034	0.258GlnHis: 0.258 ± 0.014	1.99GlnIle: 1.99 ± 0.045	1.893GlnLys: 1.893 ± 0.047	1.826GlnLeu: 1.826 ± 0.04	0.716GlnMet: 0.716 ± 0.028	1.298GlnAsn: 1.298 ± 0.032	0.635GlnPro: 0.635 ± 0.023	0.551GlnGln: 0.551 ± 0.026	1.015GlnArg: 1.015 ± 0.029	1.418GlnSer: 1.418 ± 0.045	1.229GlnThr: 1.229 ± 0.032	1.525GlnVal: 1.525 ± 0.044	0.202GlnTrp: 0.202 ± 0.013	0.955GlnTyr: 0.955 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.328ArgAla: 2.328 ± 0.054	0.417ArgCys: 0.417 ± 0.021	1.958ArgAsp: 1.958 ± 0.041	3.341ArgGlu: 3.341 ± 0.061	1.775ArgPhe: 1.775 ± 0.042	2.278ArgGly: 2.278 ± 0.05	0.573ArgHis: 0.573 ± 0.023	3.367ArgIle: 3.367 ± 0.054	3.411ArgLys: 3.411 ± 0.055	3.819ArgLeu: 3.819 ± 0.066	1.228ArgMet: 1.228 ± 0.04	2.129ArgAsn: 2.129 ± 0.048	1.01ArgPro: 1.01 ± 0.037	1.191ArgGln: 1.191 ± 0.036	1.801ArgArg: 1.801 ± 0.045	1.822ArgSer: 1.822 ± 0.043	1.938ArgThr: 1.938 ± 0.044	2.439ArgVal: 2.439 ± 0.052	0.311ArgTrp: 0.311 ± 0.018	1.751ArgTyr: 1.751 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.068SerAla: 4.068 ± 0.068	0.676SerCys: 0.676 ± 0.025	3.724SerAsp: 3.724 ± 0.068	4.671SerGlu: 4.671 ± 0.075	3.099SerPhe: 3.099 ± 0.057	5.113SerGly: 5.113 ± 0.076	0.912SerHis: 0.912 ± 0.028	4.689SerIle: 4.689 ± 0.077	4.713SerLys: 4.713 ± 0.072	5.922SerLeu: 5.922 ± 0.073	1.61SerMet: 1.61 ± 0.041	2.679SerAsn: 2.679 ± 0.059	1.711SerPro: 1.711 ± 0.044	1.321SerGln: 1.321 ± 0.039	2.235SerArg: 2.235 ± 0.046	3.777SerSer: 3.777 ± 0.084	2.86SerThr: 2.86 ± 0.055	4.46SerVal: 4.46 ± 0.062	0.502SerTrp: 0.502 ± 0.024	2.599SerTyr: 2.599 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	4.046ThrAla: 4.046 ± 0.069	0.457ThrCys: 0.457 ± 0.023	3.437ThrAsp: 3.437 ± 0.062	4.023ThrGlu: 4.023 ± 0.063	2.126ThrPhe: 2.126 ± 0.046	4.512ThrGly: 4.512 ± 0.075	0.759ThrHis: 0.759 ± 0.024	3.866ThrIle: 3.866 ± 0.063	3.854ThrLys: 3.854 ± 0.068	4.616ThrLeu: 4.616 ± 0.07	1.213ThrMet: 1.213 ± 0.032	2.191ThrAsn: 2.191 ± 0.053	1.847ThrPro: 1.847 ± 0.043	1.053ThrGln: 1.053 ± 0.036	1.71ThrArg: 1.71 ± 0.041	3.016ThrSer: 3.016 ± 0.062	2.735ThrThr: 2.735 ± 0.057	4.385ThrVal: 4.385 ± 0.074	0.367ThrTrp: 0.367 ± 0.021	1.975ThrTyr: 1.975 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.297ValAla: 4.297 ± 0.082	0.948ValCys: 0.948 ± 0.032	3.578ValAsp: 3.578 ± 0.058	4.303ValGlu: 4.303 ± 0.075	3.204ValPhe: 3.204 ± 0.055	4.133ValGly: 4.133 ± 0.057	0.866ValHis: 0.866 ± 0.031	5.703ValIle: 5.703 ± 0.089	5.803ValLys: 5.803 ± 0.084	5.983ValLeu: 5.983 ± 0.077	1.856ValMet: 1.856 ± 0.041	3.507ValAsn: 3.507 ± 0.058	2.154ValPro: 2.154 ± 0.047	1.342ValGln: 1.342 ± 0.037	2.591ValArg: 2.591 ± 0.052	4.613ValSer: 4.613 ± 0.06	3.734ValThr: 3.734 ± 0.07	4.559ValVal: 4.559 ± 0.074	0.546ValTrp: 0.546 ± 0.025	2.644ValTyr: 2.644 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.448TrpAla: 0.448 ± 0.023	0.125TrpCys: 0.125 ± 0.011	0.513TrpAsp: 0.513 ± 0.022	0.613TrpGlu: 0.613 ± 0.024	0.406TrpPhe: 0.406 ± 0.019	0.593TrpGly: 0.593 ± 0.03	0.149TrpHis: 0.149 ± 0.013	0.587TrpIle: 0.587 ± 0.021	0.754TrpLys: 0.754 ± 0.026	0.767TrpLeu: 0.767 ± 0.025	0.253TrpMet: 0.253 ± 0.016	0.517TrpAsn: 0.517 ± 0.022	0.153TrpPro: 0.153 ± 0.012	0.305TrpGln: 0.305 ± 0.017	0.317TrpArg: 0.317 ± 0.021	0.442TrpSer: 0.442 ± 0.023	0.401TrpThr: 0.401 ± 0.022	0.434TrpVal: 0.434 ± 0.022	0.1TrpTrp: 0.1 ± 0.011	0.343TrpTyr: 0.343 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.48TyrAla: 2.48 ± 0.054	0.485TyrCys: 0.485 ± 0.02	2.524TyrAsp: 2.524 ± 0.055	3.103TyrGlu: 3.103 ± 0.066	2.127TyrPhe: 2.127 ± 0.052	2.848TyrGly: 2.848 ± 0.056	0.66TyrHis: 0.66 ± 0.026	3.411TyrIle: 3.411 ± 0.064	3.508TyrLys: 3.508 ± 0.066	3.779TyrLeu: 3.779 ± 0.07	1.11TyrMet: 1.11 ± 0.038	2.37TyrAsn: 2.37 ± 0.049	1.356TyrPro: 1.356 ± 0.033	1.059TyrGln: 1.059 ± 0.032	1.834TyrArg: 1.834 ± 0.04	2.623TyrSer: 2.623 ± 0.045	2.123TyrThr: 2.123 ± 0.045	2.47TyrVal: 2.47 ± 0.046	0.359TyrTrp: 0.359 ± 0.018	1.991TyrTyr: 1.991 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3288 proteins (1036118 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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