Amino acid dipepetide frequency for Chryseotalea sanaruensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.253AlaAla: 5.253 ± 0.098	0.658AlaCys: 0.658 ± 0.026	3.763AlaAsp: 3.763 ± 0.061	4.391AlaGlu: 4.391 ± 0.063	3.562AlaPhe: 3.562 ± 0.055	5.064AlaGly: 5.064 ± 0.081	1.183AlaHis: 1.183 ± 0.032	5.46AlaIle: 5.46 ± 0.067	4.593AlaLys: 4.593 ± 0.074	7.252AlaLeu: 7.252 ± 0.085	1.75AlaMet: 1.75 ± 0.042	3.682AlaAsn: 3.682 ± 0.064	2.205AlaPro: 2.205 ± 0.056	2.767AlaGln: 2.767 ± 0.054	2.437AlaArg: 2.437 ± 0.042	4.833AlaSer: 4.833 ± 0.074	4.133AlaThr: 4.133 ± 0.086	4.507AlaVal: 4.507 ± 0.074	0.773AlaTrp: 0.773 ± 0.028	2.772AlaTyr: 2.772 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.496CysAla: 0.496 ± 0.019	0.095CysCys: 0.095 ± 0.008	0.382CysAsp: 0.382 ± 0.018	0.47CysGlu: 0.47 ± 0.02	0.358CysPhe: 0.358 ± 0.015	0.545CysGly: 0.545 ± 0.022	0.161CysHis: 0.161 ± 0.011	0.554CysIle: 0.554 ± 0.02	0.42CysLys: 0.42 ± 0.02	0.728CysLeu: 0.728 ± 0.023	0.17CysMet: 0.17 ± 0.012	0.368CysAsn: 0.368 ± 0.017	0.277CysPro: 0.277 ± 0.017	0.223CysGln: 0.223 ± 0.013	0.253CysArg: 0.253 ± 0.014	0.521CysSer: 0.521 ± 0.028	0.44CysThr: 0.44 ± 0.018	0.437CysVal: 0.437 ± 0.023	0.084CysTrp: 0.084 ± 0.009	0.278CysTyr: 0.278 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.725AspAla: 3.725 ± 0.051	0.372AspCys: 0.372 ± 0.017	2.592AspAsp: 2.592 ± 0.047	3.531AspGlu: 3.531 ± 0.057	3.317AspPhe: 3.317 ± 0.05	3.587AspGly: 3.587 ± 0.072	0.897AspHis: 0.897 ± 0.024	3.837AspIle: 3.837 ± 0.051	3.832AspLys: 3.832 ± 0.06	5.122AspLeu: 5.122 ± 0.074	1.122AspMet: 1.122 ± 0.026	2.724AspAsn: 2.724 ± 0.049	2.014AspPro: 2.014 ± 0.048	1.874AspGln: 1.874 ± 0.038	2.078AspArg: 2.078 ± 0.042	3.104AspSer: 3.104 ± 0.054	2.401AspThr: 2.401 ± 0.04	3.361AspVal: 3.361 ± 0.057	0.679AspTrp: 0.679 ± 0.023	2.463AspTyr: 2.463 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	4.784GluAla: 4.784 ± 0.068	0.282GluCys: 0.282 ± 0.016	2.995GluAsp: 2.995 ± 0.048	4.536GluGlu: 4.536 ± 0.072	2.758GluPhe: 2.758 ± 0.051	3.773GluGly: 3.773 ± 0.061	1.104GluHis: 1.104 ± 0.032	4.775GluIle: 4.775 ± 0.059	5.357GluLys: 5.357 ± 0.087	6.325GluLeu: 6.325 ± 0.085	1.494GluMet: 1.494 ± 0.042	3.577GluAsn: 3.577 ± 0.053	1.675GluPro: 1.675 ± 0.04	2.548GluGln: 2.548 ± 0.05	2.852GluArg: 2.852 ± 0.056	3.568GluSer: 3.568 ± 0.06	3.178GluThr: 3.178 ± 0.048	4.456GluVal: 4.456 ± 0.06	0.7GluTrp: 0.7 ± 0.025	2.144GluTyr: 2.144 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.317PheAla: 3.317 ± 0.056	0.414PheCys: 0.414 ± 0.016	3.067PheAsp: 3.067 ± 0.045	3.101PheGlu: 3.101 ± 0.054	2.635PhePhe: 2.635 ± 0.058	3.37PheGly: 3.37 ± 0.057	0.84PheHis: 0.84 ± 0.028	3.67PheIle: 3.67 ± 0.057	3.185PheLys: 3.185 ± 0.059	4.491PheLeu: 4.491 ± 0.074	1.083PheMet: 1.083 ± 0.028	2.958PheAsn: 2.958 ± 0.052	1.632PhePro: 1.632 ± 0.035	1.664PheGln: 1.664 ± 0.035	1.812PheArg: 1.812 ± 0.042	3.959PheSer: 3.959 ± 0.055	3.354PheThr: 3.354 ± 0.058	3.203PheVal: 3.203 ± 0.049	0.604PheTrp: 0.604 ± 0.026	2.111PheTyr: 2.111 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	4.41GlyAla: 4.41 ± 0.08	0.591GlyCys: 0.591 ± 0.029	3.272GlyAsp: 3.272 ± 0.052	3.702GlyGlu: 3.702 ± 0.051	3.575GlyPhe: 3.575 ± 0.056	4.74GlyGly: 4.74 ± 0.103	1.075GlyHis: 1.075 ± 0.035	5.239GlyIle: 5.239 ± 0.068	4.982GlyLys: 4.982 ± 0.068	6.268GlyLeu: 6.268 ± 0.082	1.633GlyMet: 1.633 ± 0.043	3.629GlyAsn: 3.629 ± 0.083	1.432GlyPro: 1.432 ± 0.037	2.099GlyGln: 2.099 ± 0.048	2.477GlyArg: 2.477 ± 0.043	4.389GlySer: 4.389 ± 0.086	4.074GlyThr: 4.074 ± 0.1	4.367GlyVal: 4.367 ± 0.073	0.821GlyTrp: 0.821 ± 0.029	2.667GlyTyr: 2.667 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.209HisAla: 1.209 ± 0.036	0.165HisCys: 0.165 ± 0.013	0.886HisAsp: 0.886 ± 0.027	1.12HisGlu: 1.12 ± 0.029	1.101HisPhe: 1.101 ± 0.028	1.095HisGly: 1.095 ± 0.031	0.509HisHis: 0.509 ± 0.023	1.215HisIle: 1.215 ± 0.03	1.073HisLys: 1.073 ± 0.029	1.768HisLeu: 1.768 ± 0.042	0.36HisMet: 0.36 ± 0.017	0.848HisAsn: 0.848 ± 0.024	0.904HisPro: 0.904 ± 0.028	0.745HisGln: 0.745 ± 0.027	0.765HisArg: 0.765 ± 0.026	1.02HisSer: 1.02 ± 0.029	1.026HisThr: 1.026 ± 0.03	1.054HisVal: 1.054 ± 0.03	0.222HisTrp: 0.222 ± 0.013	0.847HisTyr: 0.847 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.572IleAla: 5.572 ± 0.072	0.601IleCys: 0.601 ± 0.025	4.41IleAsp: 4.41 ± 0.054	4.971IleGlu: 4.971 ± 0.072	3.424IlePhe: 3.424 ± 0.062	4.988IleGly: 4.988 ± 0.069	1.343IleHis: 1.343 ± 0.03	5.318IleIle: 5.318 ± 0.074	5.046IleLys: 5.046 ± 0.071	6.55IleLeu: 6.55 ± 0.085	1.365IleMet: 1.365 ± 0.038	4.223IleAsn: 4.223 ± 0.053	2.932IlePro: 2.932 ± 0.05	2.585IleGln: 2.585 ± 0.046	3.047IleArg: 3.047 ± 0.047	5.372IleSer: 5.372 ± 0.075	4.751IleThr: 4.751 ± 0.075	4.802IleVal: 4.802 ± 0.066	0.693IleTrp: 0.693 ± 0.024	2.553IleTyr: 2.553 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.025LysAla: 5.025 ± 0.085	0.309LysCys: 0.309 ± 0.015	3.823LysAsp: 3.823 ± 0.067	5.297LysGlu: 5.297 ± 0.079	2.581LysPhe: 2.581 ± 0.042	4.244LysGly: 4.244 ± 0.07	1.306LysHis: 1.306 ± 0.036	5.121LysIle: 5.121 ± 0.075	5.71LysLys: 5.71 ± 0.091	6.381LysLeu: 6.381 ± 0.089	1.732LysMet: 1.732 ± 0.039	4.011LysAsn: 4.011 ± 0.058	2.431LysPro: 2.431 ± 0.051	2.949LysGln: 2.949 ± 0.053	3.153LysArg: 3.153 ± 0.053	4.326LysSer: 4.326 ± 0.073	3.856LysThr: 3.856 ± 0.062	4.582LysVal: 4.582 ± 0.068	0.665LysTrp: 0.665 ± 0.023	2.415LysTyr: 2.415 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.964LeuAla: 6.964 ± 0.082	0.719LeuCys: 0.719 ± 0.024	4.874LeuAsp: 4.874 ± 0.064	5.55LeuGlu: 5.55 ± 0.08	4.7LeuPhe: 4.7 ± 0.072	5.839LeuGly: 5.839 ± 0.072	1.785LeuHis: 1.785 ± 0.037	7.182LeuIle: 7.182 ± 0.089	7.207LeuLys: 7.207 ± 0.106	9.927LeuLeu: 9.927 ± 0.102	2.224LeuMet: 2.224 ± 0.041	5.491LeuAsn: 5.491 ± 0.071	3.896LeuPro: 3.896 ± 0.055	3.851LeuGln: 3.851 ± 0.061	3.915LeuArg: 3.915 ± 0.056	7.518LeuSer: 7.518 ± 0.086	5.926LeuThr: 5.926 ± 0.075	6.048LeuVal: 6.048 ± 0.072	0.87LeuTrp: 0.87 ± 0.029	3.232LeuTyr: 3.232 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.814MetAla: 1.814 ± 0.04	0.129MetCys: 0.129 ± 0.01	1.132MetAsp: 1.132 ± 0.032	1.38MetGlu: 1.38 ± 0.032	0.809MetPhe: 0.809 ± 0.027	1.483MetGly: 1.483 ± 0.035	0.438MetHis: 0.438 ± 0.02	1.496MetIle: 1.496 ± 0.036	1.879MetLys: 1.879 ± 0.036	2.245MetLeu: 2.245 ± 0.041	0.611MetMet: 0.611 ± 0.022	1.192MetAsn: 1.192 ± 0.026	0.964MetPro: 0.964 ± 0.028	0.893MetGln: 0.893 ± 0.026	1.119MetArg: 1.119 ± 0.028	1.355MetSer: 1.355 ± 0.031	1.127MetThr: 1.127 ± 0.032	1.444MetVal: 1.444 ± 0.038	0.188MetTrp: 0.188 ± 0.011	0.602MetTyr: 0.602 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.819AsnAla: 3.819 ± 0.06	0.368AsnCys: 0.368 ± 0.02	2.88AsnAsp: 2.88 ± 0.044	3.406AsnGlu: 3.406 ± 0.05	2.844AsnPhe: 2.844 ± 0.053	3.823AsnGly: 3.823 ± 0.092	0.919AsnHis: 0.919 ± 0.025	3.999AsnIle: 3.999 ± 0.052	3.49AsnLys: 3.49 ± 0.054	5.161AsnLeu: 5.161 ± 0.077	1.174AsnMet: 1.174 ± 0.03	3.312AsnAsn: 3.312 ± 0.072	2.601AsnPro: 2.601 ± 0.052	2.114AsnGln: 2.114 ± 0.041	2.201AsnArg: 2.201 ± 0.039	3.456AsnSer: 3.456 ± 0.058	3.324AsnThr: 3.324 ± 0.068	3.282AsnVal: 3.282 ± 0.051	0.76AsnTrp: 0.76 ± 0.023	2.46AsnTyr: 2.46 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	2.76ProAla: 2.76 ± 0.058	0.217ProCys: 0.217 ± 0.012	2.208ProAsp: 2.208 ± 0.042	2.649ProGlu: 2.649 ± 0.042	1.879ProPhe: 1.879 ± 0.043	2.376ProGly: 2.376 ± 0.052	0.606ProHis: 0.606 ± 0.023	2.552ProIle: 2.552 ± 0.049	2.011ProLys: 2.011 ± 0.041	3.254ProLeu: 3.254 ± 0.05	0.699ProMet: 0.699 ± 0.022	1.883ProAsn: 1.883 ± 0.048	0.985ProPro: 0.985 ± 0.035	1.211ProGln: 1.211 ± 0.03	1.108ProArg: 1.108 ± 0.029	2.326ProSer: 2.326 ± 0.045	2.04ProThr: 2.04 ± 0.055	2.783ProVal: 2.783 ± 0.063	0.377ProTrp: 0.377 ± 0.015	1.324ProTyr: 1.324 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.726GlnAla: 2.726 ± 0.051	0.181GlnCys: 0.181 ± 0.012	1.688GlnAsp: 1.688 ± 0.036	2.421GlnGlu: 2.421 ± 0.048	1.737GlnPhe: 1.737 ± 0.036	2.068GlnGly: 2.068 ± 0.04	0.84GlnHis: 0.84 ± 0.023	2.437GlnIle: 2.437 ± 0.047	2.575GlnLys: 2.575 ± 0.054	3.999GlnLeu: 3.999 ± 0.061	0.859GlnMet: 0.859 ± 0.025	2.058GlnAsn: 2.058 ± 0.046	1.293GlnPro: 1.293 ± 0.037	2.085GlnGln: 2.085 ± 0.053	1.767GlnArg: 1.767 ± 0.04	2.399GlnSer: 2.399 ± 0.045	2.039GlnThr: 2.039 ± 0.043	2.397GlnVal: 2.397 ± 0.047	0.471GlnTrp: 0.471 ± 0.018	1.521GlnTyr: 1.521 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.431ArgAla: 2.431 ± 0.041	0.242ArgCys: 0.242 ± 0.015	2.044ArgAsp: 2.044 ± 0.04	2.628ArgGlu: 2.628 ± 0.046	2.175ArgPhe: 2.175 ± 0.039	2.159ArgGly: 2.159 ± 0.048	0.688ArgHis: 0.688 ± 0.021	3.44ArgIle: 3.44 ± 0.051	3.107ArgLys: 3.107 ± 0.059	3.98ArgLeu: 3.98 ± 0.055	1.126ArgMet: 1.126 ± 0.031	2.232ArgAsn: 2.232 ± 0.042	1.256ArgPro: 1.256 ± 0.037	1.484ArgGln: 1.484 ± 0.036	1.426ArgArg: 1.426 ± 0.038	2.46ArgSer: 2.46 ± 0.044	2.149ArgThr: 2.149 ± 0.042	2.477ArgVal: 2.477 ± 0.045	0.481ArgTrp: 0.481 ± 0.02	1.794ArgTyr: 1.794 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.544SerAla: 4.544 ± 0.059	0.55SerCys: 0.55 ± 0.02	3.329SerAsp: 3.329 ± 0.05	3.539SerGlu: 3.539 ± 0.056	3.921SerPhe: 3.921 ± 0.064	4.899SerGly: 4.899 ± 0.08	1.076SerHis: 1.076 ± 0.028	5.706SerIle: 5.706 ± 0.068	4.193SerLys: 4.193 ± 0.069	6.987SerLeu: 6.987 ± 0.073	1.368SerMet: 1.368 ± 0.032	3.526SerAsn: 3.526 ± 0.057	2.359SerPro: 2.359 ± 0.047	2.145SerGln: 2.145 ± 0.043	2.483SerArg: 2.483 ± 0.042	4.551SerSer: 4.551 ± 0.083	3.935SerThr: 3.935 ± 0.069	4.477SerVal: 4.477 ± 0.073	0.754SerTrp: 0.754 ± 0.025	2.55SerTyr: 2.55 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	4.136ThrAla: 4.136 ± 0.083	0.39ThrCys: 0.39 ± 0.019	3.105ThrAsp: 3.105 ± 0.054	3.433ThrGlu: 3.433 ± 0.058	3.065ThrPhe: 3.065 ± 0.055	4.195ThrGly: 4.195 ± 0.076	1.004ThrHis: 1.004 ± 0.028	4.663ThrIle: 4.663 ± 0.078	3.39ThrLys: 3.39 ± 0.057	5.884ThrLeu: 5.884 ± 0.061	0.978ThrMet: 0.978 ± 0.027	3.082ThrAsn: 3.082 ± 0.075	2.377ThrPro: 2.377 ± 0.061	2.049ThrGln: 2.049 ± 0.039	1.954ThrArg: 1.954 ± 0.036	3.84ThrSer: 3.84 ± 0.072	3.725ThrThr: 3.725 ± 0.095	3.898ThrVal: 3.898 ± 0.086	0.68ThrTrp: 0.68 ± 0.03	2.267ThrTyr: 2.267 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.715ValAla: 4.715 ± 0.077	0.569ValCys: 0.569 ± 0.024	3.463ValAsp: 3.463 ± 0.049	3.92ValGlu: 3.92 ± 0.063	3.087ValPhe: 3.087 ± 0.043	4.108ValGly: 4.108 ± 0.064	1.088ValHis: 1.088 ± 0.027	4.731ValIle: 4.731 ± 0.067	4.548ValLys: 4.548 ± 0.07	6.436ValLeu: 6.436 ± 0.076	1.526ValMet: 1.526 ± 0.03	3.729ValAsn: 3.729 ± 0.07	2.289ValPro: 2.289 ± 0.046	2.075ValGln: 2.075 ± 0.039	2.637ValArg: 2.637 ± 0.045	4.672ValSer: 4.672 ± 0.071	3.631ValThr: 3.631 ± 0.079	4.663ValVal: 4.663 ± 0.07	0.742ValTrp: 0.742 ± 0.024	2.393ValTyr: 2.393 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.655TrpAla: 0.655 ± 0.026	0.096TrpCys: 0.096 ± 0.008	0.576TrpAsp: 0.576 ± 0.022	0.655TrpGlu: 0.655 ± 0.023	0.564TrpPhe: 0.564 ± 0.024	0.69TrpGly: 0.69 ± 0.023	0.229TrpHis: 0.229 ± 0.014	0.841TrpIle: 0.841 ± 0.03	0.789TrpLys: 0.789 ± 0.024	1.157TrpLeu: 1.157 ± 0.034	0.319TrpMet: 0.319 ± 0.017	0.627TrpAsn: 0.627 ± 0.02	0.31TrpPro: 0.31 ± 0.015	0.522TrpGln: 0.522 ± 0.02	0.521TrpArg: 0.521 ± 0.019	0.728TrpSer: 0.728 ± 0.023	0.647TrpThr: 0.647 ± 0.024	0.685TrpVal: 0.685 ± 0.022	0.167TrpTrp: 0.167 ± 0.012	0.433TrpTyr: 0.433 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.683TyrAla: 2.683 ± 0.048	0.31TyrCys: 0.31 ± 0.014	2.145TyrAsp: 2.145 ± 0.04	2.181TyrGlu: 2.181 ± 0.042	2.379TyrPhe: 2.379 ± 0.043	2.394TyrGly: 2.394 ± 0.045	0.842TyrHis: 0.842 ± 0.025	2.312TyrIle: 2.312 ± 0.041	2.531TyrLys: 2.531 ± 0.048	3.803TyrLeu: 3.803 ± 0.066	0.706TyrMet: 0.706 ± 0.025	2.239TyrAsn: 2.239 ± 0.049	1.416TyrPro: 1.416 ± 0.033	1.678TyrGln: 1.678 ± 0.038	1.776TyrArg: 1.776 ± 0.04	2.493TyrSer: 2.493 ± 0.045	2.356TyrThr: 2.356 ± 0.045	2.101TyrVal: 2.101 ± 0.033	0.481TyrTrp: 0.481 ± 0.02	1.811TyrTyr: 1.811 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3948 proteins (1390093 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---