Amino acid dipepetide frequency for Salipiger bermudensis (strain DSM 26914 / JCM 13377 / KCTC 12554 / HTCC2601) (Pelagibaca bermudensis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.969AlaAla: 16.969 ± 0.164
1.193AlaCys: 1.193 ± 0.03
6.503AlaAsp: 6.503 ± 0.078
9.164AlaGlu: 9.164 ± 0.091
4.303AlaPhe: 4.303 ± 0.057
10.804AlaGly: 10.804 ± 0.097
2.413AlaHis: 2.413 ± 0.048
5.626AlaIle: 5.626 ± 0.075
3.337AlaLys: 3.337 ± 0.059
14.861AlaLeu: 14.861 ± 0.131
3.942AlaMet: 3.942 ± 0.065
2.4AlaAsn: 2.4 ± 0.049
6.435AlaPro: 6.435 ± 0.086
4.542AlaGln: 4.542 ± 0.059
9.226AlaArg: 9.226 ± 0.1
6.038AlaSer: 6.038 ± 0.086
6.013AlaThr: 6.013 ± 0.072
8.413AlaVal: 8.413 ± 0.09
1.517AlaTrp: 1.517 ± 0.035
2.489AlaTyr: 2.489 ± 0.041
0.0AlaXaa: 0.0 ± 0.0
Cys
1.177CysAla: 1.177 ± 0.029
0.132CysCys: 0.132 ± 0.009
0.591CysAsp: 0.591 ± 0.021
0.496CysGlu: 0.496 ± 0.024
0.328CysPhe: 0.328 ± 0.015
0.956CysGly: 0.956 ± 0.03
0.277CysHis: 0.277 ± 0.015
0.404CysIle: 0.404 ± 0.017
0.187CysLys: 0.187 ± 0.011
0.815CysLeu: 0.815 ± 0.028
0.184CysMet: 0.184 ± 0.012
0.209CysAsn: 0.209 ± 0.011
0.513CysPro: 0.513 ± 0.022
0.231CysGln: 0.231 ± 0.012
0.596CysArg: 0.596 ± 0.023
0.486CysSer: 0.486 ± 0.017
0.48CysThr: 0.48 ± 0.018
0.594CysVal: 0.594 ± 0.021
0.145CysTrp: 0.145 ± 0.011
0.204CysTyr: 0.204 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
7.363AspAla: 7.363 ± 0.094
0.494AspCys: 0.494 ± 0.018
3.445AspAsp: 3.445 ± 0.107
3.869AspGlu: 3.869 ± 0.057
2.078AspPhe: 2.078 ± 0.037
5.777AspGly: 5.777 ± 0.106
1.291AspHis: 1.291 ± 0.032
2.702AspIle: 2.702 ± 0.054
1.459AspLys: 1.459 ± 0.034
6.289AspLeu: 6.289 ± 0.073
1.653AspMet: 1.653 ± 0.035
1.193AspAsn: 1.193 ± 0.036
3.793AspPro: 3.793 ± 0.06
1.621AspGln: 1.621 ± 0.033
4.276AspArg: 4.276 ± 0.058
2.368AspSer: 2.368 ± 0.07
2.95AspThr: 2.95 ± 0.082
4.013AspVal: 4.013 ± 0.077
1.191AspTrp: 1.191 ± 0.032
1.497AspTyr: 1.497 ± 0.032
0.0AspXaa: 0.0 ± 0.0
Glu
9.364GluAla: 9.364 ± 0.104
0.345GluCys: 0.345 ± 0.017
3.668GluAsp: 3.668 ± 0.056
3.986GluGlu: 3.986 ± 0.066
1.726GluPhe: 1.726 ± 0.033
5.46GluGly: 5.46 ± 0.069
1.223GluHis: 1.223 ± 0.035
4.008GluIle: 4.008 ± 0.052
1.932GluLys: 1.932 ± 0.043
5.707GluLeu: 5.707 ± 0.065
1.969GluMet: 1.969 ± 0.037
1.598GluAsn: 1.598 ± 0.036
2.876GluPro: 2.876 ± 0.051
2.143GluGln: 2.143 ± 0.038
4.718GluArg: 4.718 ± 0.069
2.429GluSer: 2.429 ± 0.042
4.267GluThr: 4.267 ± 0.057
4.459GluVal: 4.459 ± 0.069
0.686GluTrp: 0.686 ± 0.023
1.05GluTyr: 1.05 ± 0.026
0.0GluXaa: 0.0 ± 0.0
Phe
4.304PheAla: 4.304 ± 0.06
0.379PheCys: 0.379 ± 0.018
2.755PheAsp: 2.755 ± 0.041
2.333PheGlu: 2.333 ± 0.038
1.402PhePhe: 1.402 ± 0.033
3.638PheGly: 3.638 ± 0.052
0.734PheHis: 0.734 ± 0.022
1.509PheIle: 1.509 ± 0.036
0.792PheLys: 0.792 ± 0.026
3.324PheLeu: 3.324 ± 0.055
0.83PheMet: 0.83 ± 0.029
0.948PheAsn: 0.948 ± 0.026
1.544PhePro: 1.544 ± 0.034
0.943PheGln: 0.943 ± 0.027
2.137PheArg: 2.137 ± 0.042
2.056PheSer: 2.056 ± 0.041
2.045PheThr: 2.045 ± 0.039
2.606PheVal: 2.606 ± 0.046
0.549PheTrp: 0.549 ± 0.02
0.826PheTyr: 0.826 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
10.516GlyAla: 10.516 ± 0.103
0.891GlyCys: 0.891 ± 0.025
5.001GlyAsp: 5.001 ± 0.132
5.195GlyGlu: 5.195 ± 0.065
3.625GlyPhe: 3.625 ± 0.055
7.791GlyGly: 7.791 ± 0.127
2.012GlyHis: 2.012 ± 0.043
4.468GlyIle: 4.468 ± 0.071
2.845GlyLys: 2.845 ± 0.054
9.605GlyLeu: 9.605 ± 0.088
2.619GlyMet: 2.619 ± 0.049
2.111GlyAsn: 2.111 ± 0.075
3.832GlyPro: 3.832 ± 0.057
3.089GlyGln: 3.089 ± 0.048
5.96GlyArg: 5.96 ± 0.077
4.513GlySer: 4.513 ± 0.077
4.733GlyThr: 4.733 ± 0.074
6.442GlyVal: 6.442 ± 0.078
1.52GlyTrp: 1.52 ± 0.03
2.291GlyTyr: 2.291 ± 0.042
0.0GlyXaa: 0.0 ± 0.0
His
2.435HisAla: 2.435 ± 0.046
0.245HisCys: 0.245 ± 0.014
1.337HisAsp: 1.337 ± 0.03
1.168HisGlu: 1.168 ± 0.028
0.806HisPhe: 0.806 ± 0.026
2.084HisGly: 2.084 ± 0.044
0.551HisHis: 0.551 ± 0.024
0.834HisIle: 0.834 ± 0.024
0.47HisLys: 0.47 ± 0.018
2.118HisLeu: 2.118 ± 0.044
0.533HisMet: 0.533 ± 0.019
0.414HisAsn: 0.414 ± 0.016
1.361HisPro: 1.361 ± 0.03
0.535HisGln: 0.535 ± 0.018
1.437HisArg: 1.437 ± 0.033
0.873HisSer: 0.873 ± 0.022
0.753HisThr: 0.753 ± 0.021
1.538HisVal: 1.538 ± 0.042
0.359HisTrp: 0.359 ± 0.016
0.511HisTyr: 0.511 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
6.82IleAla: 6.82 ± 0.078
0.564IleCys: 0.564 ± 0.023
3.419IleAsp: 3.419 ± 0.068
3.448IleGlu: 3.448 ± 0.047
1.708IlePhe: 1.708 ± 0.04
4.705IleGly: 4.705 ± 0.066
0.88IleHis: 0.88 ± 0.025
1.941IleIle: 1.941 ± 0.043
1.091IleLys: 1.091 ± 0.03
4.536IleLeu: 4.536 ± 0.06
0.997IleMet: 0.997 ± 0.03
1.177IleAsn: 1.177 ± 0.033
2.252IlePro: 2.252 ± 0.045
1.044IleGln: 1.044 ± 0.023
3.161IleArg: 3.161 ± 0.05
2.87IleSer: 2.87 ± 0.048
2.722IleThr: 2.722 ± 0.052
3.674IleVal: 3.674 ± 0.053
0.677IleTrp: 0.677 ± 0.023
1.041IleTyr: 1.041 ± 0.026
0.0IleXaa: 0.0 ± 0.0
Lys
3.53LysAla: 3.53 ± 0.068
0.17LysCys: 0.17 ± 0.011
1.438LysAsp: 1.438 ± 0.037
1.336LysGlu: 1.336 ± 0.034
0.736LysPhe: 0.736 ± 0.024
2.438LysGly: 2.438 ± 0.044
0.537LysHis: 0.537 ± 0.018
1.456LysIle: 1.456 ± 0.029
0.987LysLys: 0.987 ± 0.031
2.772LysLeu: 2.772 ± 0.051
0.727LysMet: 0.727 ± 0.027
0.605LysAsn: 0.605 ± 0.023
1.646LysPro: 1.646 ± 0.034
0.802LysGln: 0.802 ± 0.023
2.087LysArg: 2.087 ± 0.043
1.524LysSer: 1.524 ± 0.031
1.729LysThr: 1.729 ± 0.045
2.092LysVal: 2.092 ± 0.044
0.315LysTrp: 0.315 ± 0.013
0.548LysTyr: 0.548 ± 0.021
0.0LysXaa: 0.0 ± 0.0
Leu
13.413LeuAla: 13.413 ± 0.122
1.062LeuCys: 1.062 ± 0.034
6.133LeuAsp: 6.133 ± 0.07
6.046LeuGlu: 6.046 ± 0.072
3.541LeuPhe: 3.541 ± 0.059
8.895LeuGly: 8.895 ± 0.081
1.957LeuHis: 1.957 ± 0.041
4.896LeuIle: 4.896 ± 0.062
2.842LeuLys: 2.842 ± 0.045
9.57LeuLeu: 9.57 ± 0.112
2.662LeuMet: 2.662 ± 0.049
2.375LeuAsn: 2.375 ± 0.041
5.863LeuPro: 5.863 ± 0.078
2.747LeuGln: 2.747 ± 0.049
7.443LeuArg: 7.443 ± 0.098
6.806LeuSer: 6.806 ± 0.067
5.981LeuThr: 5.981 ± 0.062
7.137LeuVal: 7.137 ± 0.083
1.316LeuTrp: 1.316 ± 0.032
2.011LeuTyr: 2.011 ± 0.036
0.0LeuXaa: 0.0 ± 0.0
Met
3.437MetAla: 3.437 ± 0.049
0.204MetCys: 0.204 ± 0.011
1.301MetAsp: 1.301 ± 0.028
1.374MetGlu: 1.374 ± 0.034
0.791MetPhe: 0.791 ± 0.024
2.26MetGly: 2.26 ± 0.042
0.46MetHis: 0.46 ± 0.018
1.523MetIle: 1.523 ± 0.031
0.986MetLys: 0.986 ± 0.023
2.786MetLeu: 2.786 ± 0.047
0.837MetMet: 0.837 ± 0.026
0.736MetAsn: 0.736 ± 0.024
1.614MetPro: 1.614 ± 0.036
0.99MetGln: 0.99 ± 0.027
1.989MetArg: 1.989 ± 0.032
1.876MetSer: 1.876 ± 0.04
2.153MetThr: 2.153 ± 0.039
1.916MetVal: 1.916 ± 0.037
0.234MetTrp: 0.234 ± 0.014
0.32MetTyr: 0.32 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.934AsnAla: 2.934 ± 0.056
0.234AsnCys: 0.234 ± 0.012
1.354AsnAsp: 1.354 ± 0.067
1.154AsnGlu: 1.154 ± 0.031
0.84AsnPhe: 0.84 ± 0.026
2.273AsnGly: 2.273 ± 0.057
0.464AsnHis: 0.464 ± 0.018
1.203AsnIle: 1.203 ± 0.026
0.538AsnLys: 0.538 ± 0.018
2.239AsnLeu: 2.239 ± 0.039
0.656AsnMet: 0.656 ± 0.023
0.562AsnAsn: 0.562 ± 0.022
1.658AsnPro: 1.658 ± 0.037
0.61AsnGln: 0.61 ± 0.021
1.62AsnArg: 1.62 ± 0.034
1.011AsnSer: 1.011 ± 0.038
1.232AsnThr: 1.232 ± 0.043
1.702AsnVal: 1.702 ± 0.037
0.395AsnTrp: 0.395 ± 0.015
0.577AsnTyr: 0.577 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
6.124ProAla: 6.124 ± 0.079
0.388ProCys: 0.388 ± 0.017
3.809ProAsp: 3.809 ± 0.07
4.866ProGlu: 4.866 ± 0.069
1.949ProPhe: 1.949 ± 0.037
4.836ProGly: 4.836 ± 0.059
1.062ProHis: 1.062 ± 0.027
2.077ProIle: 2.077 ± 0.043
1.532ProLys: 1.532 ± 0.035
4.916ProLeu: 4.916 ± 0.08
1.366ProMet: 1.366 ± 0.034
1.165ProAsn: 1.165 ± 0.027
2.469ProPro: 2.469 ± 0.087
1.772ProGln: 1.772 ± 0.033
3.107ProArg: 3.107 ± 0.048
2.74ProSer: 2.74 ± 0.043
2.347ProThr: 2.347 ± 0.048
4.373ProVal: 4.373 ± 0.058
0.667ProTrp: 0.667 ± 0.024
1.143ProTyr: 1.143 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
3.934GlnAla: 3.934 ± 0.06
0.182GlnCys: 0.182 ± 0.011
1.686GlnAsp: 1.686 ± 0.039
1.651GlnGlu: 1.651 ± 0.032
0.982GlnPhe: 0.982 ± 0.024
2.637GlnGly: 2.637 ± 0.045
0.594GlnHis: 0.594 ± 0.02
1.863GlnIle: 1.863 ± 0.035
0.882GlnLys: 0.882 ± 0.025
2.88GlnLeu: 2.88 ± 0.047
0.999GlnMet: 0.999 ± 0.026
0.772GlnAsn: 0.772 ± 0.024
1.625GlnPro: 1.625 ± 0.037
1.103GlnGln: 1.103 ± 0.034
2.296GlnArg: 2.296 ± 0.044
1.764GlnSer: 1.764 ± 0.034
1.708GlnThr: 1.708 ± 0.036
2.318GlnVal: 2.318 ± 0.038
0.37GlnTrp: 0.37 ± 0.015
0.567GlnTyr: 0.567 ± 0.019
0.0GlnXaa: 0.0 ± 0.0
Arg
8.484ArgAla: 8.484 ± 0.094
0.572ArgCys: 0.572 ± 0.023
4.386ArgAsp: 4.386 ± 0.055
4.279ArgGlu: 4.279 ± 0.064
2.742ArgPhe: 2.742 ± 0.046
4.996ArgGly: 4.996 ± 0.069
1.695ArgHis: 1.695 ± 0.041
3.766ArgIle: 3.766 ± 0.052
2.122ArgLys: 2.122 ± 0.043
7.687ArgLeu: 7.687 ± 0.099
2.04ArgMet: 2.04 ± 0.037
1.742ArgAsn: 1.742 ± 0.033
3.579ArgPro: 3.579 ± 0.063
2.316ArgGln: 2.316 ± 0.044
5.56ArgArg: 5.56 ± 0.091
3.497ArgSer: 3.497 ± 0.05
2.858ArgThr: 2.858 ± 0.045
4.687ArgVal: 4.687 ± 0.065
0.952ArgTrp: 0.952 ± 0.027
1.513ArgTyr: 1.513 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
6.244SerAla: 6.244 ± 0.091
0.503SerCys: 0.503 ± 0.022
3.215SerAsp: 3.215 ± 0.061
3.304SerGlu: 3.304 ± 0.053
2.247SerPhe: 2.247 ± 0.038
5.566SerGly: 5.566 ± 0.086
1.059SerHis: 1.059 ± 0.027
2.38SerIle: 2.38 ± 0.05
1.366SerLys: 1.366 ± 0.03
5.097SerLeu: 5.097 ± 0.062
1.446SerMet: 1.446 ± 0.03
1.266SerAsn: 1.266 ± 0.036
2.652SerPro: 2.652 ± 0.048
1.542SerGln: 1.542 ± 0.034
3.476SerArg: 3.476 ± 0.052
2.829SerSer: 2.829 ± 0.058
2.542SerThr: 2.542 ± 0.047
3.834SerVal: 3.834 ± 0.07
0.772SerTrp: 0.772 ± 0.024
1.332SerTyr: 1.332 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
6.23ThrAla: 6.23 ± 0.083
0.471ThrCys: 0.471 ± 0.021
3.065ThrAsp: 3.065 ± 0.059
3.284ThrGlu: 3.284 ± 0.051
1.862ThrPhe: 1.862 ± 0.027
5.494ThrGly: 5.494 ± 0.075
1.013ThrHis: 1.013 ± 0.027
2.522ThrIle: 2.522 ± 0.056
1.216ThrLys: 1.216 ± 0.033
6.09ThrLeu: 6.09 ± 0.073
1.283ThrMet: 1.283 ± 0.031
1.178ThrAsn: 1.178 ± 0.036
3.444ThrPro: 3.444 ± 0.064
1.494ThrGln: 1.494 ± 0.031
3.66ThrArg: 3.66 ± 0.05
2.63ThrSer: 2.63 ± 0.053
2.827ThrThr: 2.827 ± 0.054
4.331ThrVal: 4.331 ± 0.072
0.662ThrTrp: 0.662 ± 0.019
1.174ThrTyr: 1.174 ± 0.029
0.0ThrXaa: 0.0 ± 0.0
Val
9.068ValAla: 9.068 ± 0.084
0.605ValCys: 0.605 ± 0.021
3.909ValAsp: 3.909 ± 0.064
4.622ValGlu: 4.622 ± 0.059
2.674ValPhe: 2.674 ± 0.047
5.3ValGly: 5.3 ± 0.075
1.294ValHis: 1.294 ± 0.031
4.015ValIle: 4.015 ± 0.061
1.945ValLys: 1.945 ± 0.036
7.557ValLeu: 7.557 ± 0.084
2.162ValMet: 2.162 ± 0.042
1.841ValAsn: 1.841 ± 0.038
3.758ValPro: 3.758 ± 0.062
2.062ValGln: 2.062 ± 0.035
4.068ValArg: 4.068 ± 0.055
4.493ValSer: 4.493 ± 0.08
4.738ValThr: 4.738 ± 0.077
5.569ValVal: 5.569 ± 0.066
0.948ValTrp: 0.948 ± 0.028
1.427ValTyr: 1.427 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.324TrpAla: 1.324 ± 0.031
0.141TrpCys: 0.141 ± 0.01
0.724TrpAsp: 0.724 ± 0.023
0.706TrpGlu: 0.706 ± 0.024
0.512TrpPhe: 0.512 ± 0.018
1.041TrpGly: 1.041 ± 0.028
0.348TrpHis: 0.348 ± 0.015
0.696TrpIle: 0.696 ± 0.025
0.439TrpLys: 0.439 ± 0.015
1.656TrpLeu: 1.656 ± 0.039
0.421TrpMet: 0.421 ± 0.016
0.404TrpAsn: 0.404 ± 0.018
0.751TrpPro: 0.751 ± 0.023
0.603TrpGln: 0.603 ± 0.02
1.151TrpArg: 1.151 ± 0.034
0.819TrpSer: 0.819 ± 0.025
0.746TrpThr: 0.746 ± 0.022
0.873TrpVal: 0.873 ± 0.023
0.204TrpTrp: 0.204 ± 0.012
0.273TrpTyr: 0.273 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.518TyrAla: 2.518 ± 0.05
0.232TyrCys: 0.232 ± 0.011
1.584TyrAsp: 1.584 ± 0.035
1.331TyrGlu: 1.331 ± 0.029
0.804TyrPhe: 0.804 ± 0.024
2.109TyrGly: 2.109 ± 0.04
0.496TyrHis: 0.496 ± 0.022
0.844TyrIle: 0.844 ± 0.02
0.508TyrLys: 0.508 ± 0.019
2.188TyrLeu: 2.188 ± 0.037
0.458TyrMet: 0.458 ± 0.017
0.561TyrAsn: 0.561 ± 0.019
1.041TyrPro: 1.041 ± 0.025
0.626TyrGln: 0.626 ± 0.023
1.504TyrArg: 1.504 ± 0.035
1.048TyrSer: 1.048 ± 0.027
1.107TyrThr: 1.107 ± 0.028
1.486TyrVal: 1.486 ± 0.033
0.353TyrTrp: 0.353 ± 0.014
0.569TyrTyr: 0.569 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5420 proteins (1601589 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski