Amino acid dipepetide frequency for Burkholderia phage Bcep781 (isolate -/United States/Beer/1978) (Bacteriophage Bcep781)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
22.517AlaAla: 22.517 ± 1.742
1.266AlaCys: 1.266 ± 0.308
7.794AlaAsp: 7.794 ± 0.647
4.663AlaGlu: 4.663 ± 0.457
5.263AlaPhe: 5.263 ± 0.493
11.658AlaGly: 11.658 ± 1.155
2.665AlaHis: 2.665 ± 0.358
6.795AlaIle: 6.795 ± 0.665
4.264AlaLys: 4.264 ± 0.539
13.124AlaLeu: 13.124 ± 1.031
3.997AlaMet: 3.997 ± 0.488
5.196AlaAsn: 5.196 ± 0.518
6.928AlaPro: 6.928 ± 0.649
6.728AlaGln: 6.728 ± 0.815
8.993AlaArg: 8.993 ± 0.898
7.061AlaSer: 7.061 ± 0.838
9.06AlaThr: 9.06 ± 0.911
8.127AlaVal: 8.127 ± 0.86
1.332AlaTrp: 1.332 ± 0.25
2.931AlaTyr: 2.931 ± 0.494
0.0AlaXaa: 0.0 ± 0.0
Cys
1.266CysAla: 1.266 ± 0.248
0.067CysCys: 0.067 ± 0.073
0.866CysAsp: 0.866 ± 0.23
0.333CysGlu: 0.333 ± 0.226
0.333CysPhe: 0.333 ± 0.144
1.466CysGly: 1.466 ± 0.326
0.266CysHis: 0.266 ± 0.124
0.333CysIle: 0.333 ± 0.147
0.533CysLys: 0.533 ± 0.233
0.799CysLeu: 0.799 ± 0.2
0.266CysMet: 0.266 ± 0.147
0.2CysAsn: 0.2 ± 0.119
0.6CysPro: 0.6 ± 0.224
0.067CysGln: 0.067 ± 0.076
0.666CysArg: 0.666 ± 0.214
0.6CysSer: 0.6 ± 0.195
0.666CysThr: 0.666 ± 0.24
0.266CysVal: 0.266 ± 0.12
0.067CysTrp: 0.067 ± 0.061
0.333CysTyr: 0.333 ± 0.138
0.0CysXaa: 0.0 ± 0.0
Asp
10.259AspAla: 10.259 ± 0.959
1.066AspCys: 1.066 ± 0.264
3.331AspAsp: 3.331 ± 0.552
3.264AspGlu: 3.264 ± 0.48
2.198AspPhe: 2.198 ± 0.429
5.063AspGly: 5.063 ± 0.609
0.4AspHis: 0.4 ± 0.144
2.865AspIle: 2.865 ± 0.469
2.065AspLys: 2.065 ± 0.421
4.863AspLeu: 4.863 ± 0.686
1.133AspMet: 1.133 ± 0.273
1.799AspAsn: 1.799 ± 0.454
3.597AspPro: 3.597 ± 0.397
1.932AspGln: 1.932 ± 0.381
2.865AspArg: 2.865 ± 0.444
2.332AspSer: 2.332 ± 0.37
3.797AspThr: 3.797 ± 0.517
4.13AspVal: 4.13 ± 0.461
1.199AspTrp: 1.199 ± 0.289
1.865AspTyr: 1.865 ± 0.376
0.0AspXaa: 0.0 ± 0.0
Glu
5.862GluAla: 5.862 ± 0.757
0.866GluCys: 0.866 ± 0.27
1.599GluAsp: 1.599 ± 0.351
1.466GluGlu: 1.466 ± 0.311
2.332GluPhe: 2.332 ± 0.366
2.798GluGly: 2.798 ± 0.422
1.066GluHis: 1.066 ± 0.275
2.132GluIle: 2.132 ± 0.406
1.466GluLys: 1.466 ± 0.255
3.664GluLeu: 3.664 ± 0.518
0.799GluMet: 0.799 ± 0.225
1.399GluAsn: 1.399 ± 0.274
2.132GluPro: 2.132 ± 0.331
2.731GluGln: 2.731 ± 0.471
3.997GluArg: 3.997 ± 0.601
1.932GluSer: 1.932 ± 0.382
1.999GluThr: 1.999 ± 0.348
2.998GluVal: 2.998 ± 0.387
1.066GluTrp: 1.066 ± 0.285
1.799GluTyr: 1.799 ± 0.391
0.0GluXaa: 0.0 ± 0.0
Phe
5.063PheAla: 5.063 ± 0.595
0.133PheCys: 0.133 ± 0.093
3.198PheAsp: 3.198 ± 0.477
1.865PheGlu: 1.865 ± 0.298
0.933PhePhe: 0.933 ± 0.257
3.264PheGly: 3.264 ± 0.514
0.266PheHis: 0.266 ± 0.135
1.266PheIle: 1.266 ± 0.265
0.799PheLys: 0.799 ± 0.261
2.531PheLeu: 2.531 ± 0.401
0.733PheMet: 0.733 ± 0.226
2.065PheAsn: 2.065 ± 0.395
1.799PhePro: 1.799 ± 0.397
1.466PheGln: 1.466 ± 0.288
1.599PheArg: 1.599 ± 0.339
1.266PheSer: 1.266 ± 0.352
2.265PheThr: 2.265 ± 0.385
3.664PheVal: 3.664 ± 0.5
0.533PheTrp: 0.533 ± 0.212
1.133PheTyr: 1.133 ± 0.25
0.0PheXaa: 0.0 ± 0.0
Gly
11.991GlyAla: 11.991 ± 1.003
0.666GlyCys: 0.666 ± 0.2
3.93GlyAsp: 3.93 ± 0.519
2.865GlyGlu: 2.865 ± 0.338
3.93GlyPhe: 3.93 ± 0.602
7.395GlyGly: 7.395 ± 1.044
1.399GlyHis: 1.399 ± 0.327
4.264GlyIle: 4.264 ± 0.557
3.597GlyLys: 3.597 ± 0.452
6.928GlyLeu: 6.928 ± 0.661
1.665GlyMet: 1.665 ± 0.258
2.531GlyAsn: 2.531 ± 0.712
1.865GlyPro: 1.865 ± 0.286
2.931GlyGln: 2.931 ± 0.395
5.196GlyArg: 5.196 ± 0.77
3.93GlySer: 3.93 ± 0.597
6.595GlyThr: 6.595 ± 0.816
5.796GlyVal: 5.796 ± 0.542
1.332GlyTrp: 1.332 ± 0.283
2.731GlyTyr: 2.731 ± 0.45
0.0GlyXaa: 0.0 ± 0.0
His
2.265HisAla: 2.265 ± 0.381
0.2HisCys: 0.2 ± 0.121
1.532HisAsp: 1.532 ± 0.255
0.6HisGlu: 0.6 ± 0.2
0.533HisPhe: 0.533 ± 0.163
2.065HisGly: 2.065 ± 0.368
0.4HisHis: 0.4 ± 0.202
0.666HisIle: 0.666 ± 0.176
0.533HisLys: 0.533 ± 0.165
1.332HisLeu: 1.332 ± 0.361
0.466HisMet: 0.466 ± 0.162
0.466HisAsn: 0.466 ± 0.186
0.799HisPro: 0.799 ± 0.236
0.4HisGln: 0.4 ± 0.176
1.133HisArg: 1.133 ± 0.228
0.799HisSer: 0.799 ± 0.249
0.866HisThr: 0.866 ± 0.258
1.665HisVal: 1.665 ± 0.379
0.2HisTrp: 0.2 ± 0.148
0.466HisTyr: 0.466 ± 0.19
0.0HisXaa: 0.0 ± 0.0
Ile
6.462IleAla: 6.462 ± 0.671
0.266IleCys: 0.266 ± 0.144
4.863IleAsp: 4.863 ± 0.617
3.531IleGlu: 3.531 ± 0.5
0.733IlePhe: 0.733 ± 0.213
3.997IleGly: 3.997 ± 0.522
0.799IleHis: 0.799 ± 0.303
1.466IleIle: 1.466 ± 0.329
1.599IleLys: 1.599 ± 0.293
2.731IleLeu: 2.731 ± 0.499
0.666IleMet: 0.666 ± 0.241
2.198IleAsn: 2.198 ± 0.315
2.598IlePro: 2.598 ± 0.442
2.065IleGln: 2.065 ± 0.337
2.398IleArg: 2.398 ± 0.399
2.332IleSer: 2.332 ± 0.365
2.731IleThr: 2.731 ± 0.415
3.731IleVal: 3.731 ± 0.442
0.799IleTrp: 0.799 ± 0.208
1.266IleTyr: 1.266 ± 0.322
0.0IleXaa: 0.0 ± 0.0
Lys
4.33LysAla: 4.33 ± 0.608
0.266LysCys: 0.266 ± 0.119
1.799LysAsp: 1.799 ± 0.416
1.066LysGlu: 1.066 ± 0.25
1.266LysPhe: 1.266 ± 0.306
1.999LysGly: 1.999 ± 0.351
1.199LysHis: 1.199 ± 0.327
0.999LysIle: 0.999 ± 0.301
1.799LysLys: 1.799 ± 0.401
3.597LysLeu: 3.597 ± 0.401
0.666LysMet: 0.666 ± 0.198
0.733LysAsn: 0.733 ± 0.211
1.532LysPro: 1.532 ± 0.331
1.532LysGln: 1.532 ± 0.284
1.999LysArg: 1.999 ± 0.384
1.399LysSer: 1.399 ± 0.289
1.999LysThr: 1.999 ± 0.391
1.799LysVal: 1.799 ± 0.375
0.333LysTrp: 0.333 ± 0.148
0.999LysTyr: 0.999 ± 0.199
0.0LysXaa: 0.0 ± 0.0
Leu
9.593LeuAla: 9.593 ± 0.789
0.866LeuCys: 0.866 ± 0.271
5.263LeuAsp: 5.263 ± 0.703
3.331LeuGlu: 3.331 ± 0.404
2.598LeuPhe: 2.598 ± 0.41
6.329LeuGly: 6.329 ± 0.768
1.532LeuHis: 1.532 ± 0.305
4.33LeuIle: 4.33 ± 0.534
2.531LeuLys: 2.531 ± 0.303
5.396LeuLeu: 5.396 ± 0.821
1.999LeuMet: 1.999 ± 0.373
3.597LeuAsn: 3.597 ± 0.417
5.729LeuPro: 5.729 ± 0.758
3.997LeuGln: 3.997 ± 0.505
5.13LeuArg: 5.13 ± 0.662
4.93LeuSer: 4.93 ± 0.496
6.862LeuThr: 6.862 ± 0.695
5.063LeuVal: 5.063 ± 0.6
1.332LeuTrp: 1.332 ± 0.267
1.732LeuTyr: 1.732 ± 0.36
0.0LeuXaa: 0.0 ± 0.0
Met
1.999MetAla: 1.999 ± 0.339
0.266MetCys: 0.266 ± 0.147
1.066MetAsp: 1.066 ± 0.294
0.799MetGlu: 0.799 ± 0.222
0.933MetPhe: 0.933 ± 0.258
1.133MetGly: 1.133 ± 0.287
0.333MetHis: 0.333 ± 0.119
1.066MetIle: 1.066 ± 0.236
1.266MetLys: 1.266 ± 0.285
2.065MetLeu: 2.065 ± 0.384
0.333MetMet: 0.333 ± 0.15
1.066MetAsn: 1.066 ± 0.226
1.599MetPro: 1.599 ± 0.312
0.733MetGln: 0.733 ± 0.198
1.799MetArg: 1.799 ± 0.292
1.532MetSer: 1.532 ± 0.263
2.598MetThr: 2.598 ± 0.354
1.066MetVal: 1.066 ± 0.22
0.533MetTrp: 0.533 ± 0.192
0.666MetTyr: 0.666 ± 0.263
0.0MetXaa: 0.0 ± 0.0
Asn
5.729AsnAla: 5.729 ± 0.788
0.4AsnCys: 0.4 ± 0.134
1.532AsnAsp: 1.532 ± 0.34
2.332AsnGlu: 2.332 ± 0.502
1.199AsnPhe: 1.199 ± 0.279
3.93AsnGly: 3.93 ± 0.557
0.466AsnHis: 0.466 ± 0.156
1.999AsnIle: 1.999 ± 0.353
0.799AsnLys: 0.799 ± 0.21
2.132AsnLeu: 2.132 ± 0.413
0.4AsnMet: 0.4 ± 0.179
1.466AsnAsn: 1.466 ± 0.347
3.198AsnPro: 3.198 ± 0.605
1.399AsnGln: 1.399 ± 0.318
1.599AsnArg: 1.599 ± 0.336
2.265AsnSer: 2.265 ± 0.368
2.265AsnThr: 2.265 ± 0.509
2.731AsnVal: 2.731 ± 0.471
0.799AsnTrp: 0.799 ± 0.226
1.399AsnTyr: 1.399 ± 0.395
0.0AsnXaa: 0.0 ± 0.0
Pro
6.862ProAla: 6.862 ± 0.574
0.133ProCys: 0.133 ± 0.101
3.997ProAsp: 3.997 ± 0.492
2.531ProGlu: 2.531 ± 0.365
2.731ProPhe: 2.731 ± 0.494
4.73ProGly: 4.73 ± 0.79
1.199ProHis: 1.199 ± 0.291
2.598ProIle: 2.598 ± 0.383
1.266ProLys: 1.266 ± 0.253
4.264ProLeu: 4.264 ± 0.483
1.133ProMet: 1.133 ± 0.255
2.332ProAsn: 2.332 ± 0.344
2.798ProPro: 2.798 ± 0.481
2.398ProGln: 2.398 ± 0.399
3.064ProArg: 3.064 ± 0.338
2.931ProSer: 2.931 ± 0.491
4.33ProThr: 4.33 ± 0.659
3.864ProVal: 3.864 ± 0.48
0.733ProTrp: 0.733 ± 0.217
1.665ProTyr: 1.665 ± 0.382
0.0ProXaa: 0.0 ± 0.0
Gln
5.13GlnAla: 5.13 ± 0.516
0.4GlnCys: 0.4 ± 0.159
1.865GlnAsp: 1.865 ± 0.384
1.133GlnGlu: 1.133 ± 0.322
1.665GlnPhe: 1.665 ± 0.376
2.931GlnGly: 2.931 ± 0.392
1.332GlnHis: 1.332 ± 0.275
2.998GlnIle: 2.998 ± 0.393
0.6GlnLys: 0.6 ± 0.152
4.663GlnLeu: 4.663 ± 0.742
0.466GlnMet: 0.466 ± 0.16
1.399GlnAsn: 1.399 ± 0.314
2.998GlnPro: 2.998 ± 0.378
1.932GlnGln: 1.932 ± 0.437
2.931GlnArg: 2.931 ± 0.524
1.999GlnSer: 1.999 ± 0.369
2.065GlnThr: 2.065 ± 0.275
2.798GlnVal: 2.798 ± 0.442
0.733GlnTrp: 0.733 ± 0.253
1.133GlnTyr: 1.133 ± 0.233
0.0GlnXaa: 0.0 ± 0.0
Arg
9.193ArgAla: 9.193 ± 0.908
0.6ArgCys: 0.6 ± 0.22
3.864ArgAsp: 3.864 ± 0.552
4.197ArgGlu: 4.197 ± 0.623
2.265ArgPhe: 2.265 ± 0.523
3.331ArgGly: 3.331 ± 0.572
0.866ArgHis: 0.866 ± 0.249
2.931ArgIle: 2.931 ± 0.364
1.532ArgLys: 1.532 ± 0.369
4.93ArgLeu: 4.93 ± 0.62
2.398ArgMet: 2.398 ± 0.415
2.198ArgAsn: 2.198 ± 0.367
3.131ArgPro: 3.131 ± 0.492
2.731ArgGln: 2.731 ± 0.506
4.397ArgArg: 4.397 ± 0.728
2.465ArgSer: 2.465 ± 0.428
3.464ArgThr: 3.464 ± 0.34
4.33ArgVal: 4.33 ± 0.588
0.6ArgTrp: 0.6 ± 0.184
2.265ArgTyr: 2.265 ± 0.275
0.0ArgXaa: 0.0 ± 0.0
Ser
7.195SerAla: 7.195 ± 0.81
0.266SerCys: 0.266 ± 0.121
2.598SerAsp: 2.598 ± 0.353
2.065SerGlu: 2.065 ± 0.396
1.532SerPhe: 1.532 ± 0.31
5.529SerGly: 5.529 ± 0.658
0.666SerHis: 0.666 ± 0.194
2.265SerIle: 2.265 ± 0.395
1.466SerLys: 1.466 ± 0.341
3.597SerLeu: 3.597 ± 0.507
1.332SerMet: 1.332 ± 0.304
1.932SerAsn: 1.932 ± 0.346
2.865SerPro: 2.865 ± 0.371
1.865SerGln: 1.865 ± 0.338
3.064SerArg: 3.064 ± 0.343
3.331SerSer: 3.331 ± 0.567
4.13SerThr: 4.13 ± 0.68
3.664SerVal: 3.664 ± 0.489
0.666SerTrp: 0.666 ± 0.18
1.466SerTyr: 1.466 ± 0.287
0.0SerXaa: 0.0 ± 0.0
Thr
8.993ThrAla: 8.993 ± 0.974
0.933ThrCys: 0.933 ± 0.269
3.797ThrAsp: 3.797 ± 0.523
2.665ThrGlu: 2.665 ± 0.419
2.332ThrPhe: 2.332 ± 0.338
6.129ThrGly: 6.129 ± 0.896
0.666ThrHis: 0.666 ± 0.203
4.197ThrIle: 4.197 ± 0.501
1.532ThrLys: 1.532 ± 0.241
5.329ThrLeu: 5.329 ± 0.689
1.199ThrMet: 1.199 ± 0.264
3.131ThrAsn: 3.131 ± 0.464
5.196ThrPro: 5.196 ± 0.575
1.932ThrGln: 1.932 ± 0.36
2.865ThrArg: 2.865 ± 0.445
4.796ThrSer: 4.796 ± 0.758
4.397ThrThr: 4.397 ± 0.656
4.663ThrVal: 4.663 ± 0.599
1.332ThrTrp: 1.332 ± 0.29
1.799ThrTyr: 1.799 ± 0.311
0.0ThrXaa: 0.0 ± 0.0
Val
9.993ValAla: 9.993 ± 0.933
0.6ValCys: 0.6 ± 0.193
4.064ValAsp: 4.064 ± 0.472
3.664ValGlu: 3.664 ± 0.442
1.532ValPhe: 1.532 ± 0.33
4.463ValGly: 4.463 ± 0.602
1.199ValHis: 1.199 ± 0.29
2.398ValIle: 2.398 ± 0.445
2.398ValLys: 2.398 ± 0.448
6.329ValLeu: 6.329 ± 0.504
1.999ValMet: 1.999 ± 0.348
2.465ValAsn: 2.465 ± 0.267
4.13ValPro: 4.13 ± 0.476
2.265ValGln: 2.265 ± 0.401
4.264ValArg: 4.264 ± 0.627
3.264ValSer: 3.264 ± 0.451
5.663ValThr: 5.663 ± 0.77
3.597ValVal: 3.597 ± 0.468
0.933ValTrp: 0.933 ± 0.258
1.799ValTyr: 1.799 ± 0.25
0.0ValXaa: 0.0 ± 0.0
Trp
1.599TrpAla: 1.599 ± 0.384
0.2TrpCys: 0.2 ± 0.102
0.733TrpAsp: 0.733 ± 0.172
0.4TrpGlu: 0.4 ± 0.17
0.6TrpPhe: 0.6 ± 0.185
0.866TrpGly: 0.866 ± 0.266
0.266TrpHis: 0.266 ± 0.116
0.666TrpIle: 0.666 ± 0.199
0.266TrpLys: 0.266 ± 0.166
1.399TrpLeu: 1.399 ± 0.274
0.533TrpMet: 0.533 ± 0.184
0.533TrpAsn: 0.533 ± 0.18
0.733TrpPro: 0.733 ± 0.244
1.133TrpGln: 1.133 ± 0.26
1.399TrpArg: 1.399 ± 0.273
0.933TrpSer: 0.933 ± 0.261
0.999TrpThr: 0.999 ± 0.247
0.733TrpVal: 0.733 ± 0.19
0.533TrpTrp: 0.533 ± 0.188
0.933TrpTyr: 0.933 ± 0.267
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.064TyrAla: 4.064 ± 0.53
0.533TyrCys: 0.533 ± 0.16
2.332TyrAsp: 2.332 ± 0.348
1.332TyrGlu: 1.332 ± 0.331
0.933TyrPhe: 0.933 ± 0.246
2.465TyrGly: 2.465 ± 0.397
0.4TyrHis: 0.4 ± 0.234
0.999TyrIle: 0.999 ± 0.263
0.999TyrLys: 0.999 ± 0.228
2.465TyrLeu: 2.465 ± 0.345
0.6TyrMet: 0.6 ± 0.193
1.332TyrAsn: 1.332 ± 0.254
1.332TyrPro: 1.332 ± 0.395
0.999TyrGln: 0.999 ± 0.243
2.332TyrArg: 2.332 ± 0.334
1.399TyrSer: 1.399 ± 0.397
1.133TyrThr: 1.133 ± 0.312
2.332TyrVal: 2.332 ± 0.339
0.4TyrTrp: 0.4 ± 0.133
0.533TyrTyr: 0.533 ± 0.185
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 66 proteins (15012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski