Amino acid dipepetide frequency for Puccinia triticina (isolate 1-1 / race 1 (BBBD)) (Brown leaf rust fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.025AlaAla: 8.025 ± 0.064	1.024AlaCys: 1.024 ± 0.015	4.227AlaAsp: 4.227 ± 0.029	4.743AlaGlu: 4.743 ± 0.041	2.633AlaPhe: 2.633 ± 0.023	5.305AlaGly: 5.305 ± 0.044	2.155AlaHis: 2.155 ± 0.026	3.967AlaIle: 3.967 ± 0.032	4.254AlaLys: 4.254 ± 0.038	7.204AlaLeu: 7.204 ± 0.051	1.557AlaMet: 1.557 ± 0.02	3.284AlaAsn: 3.284 ± 0.027	5.569AlaPro: 5.569 ± 0.05	3.644AlaGln: 3.644 ± 0.034	4.811AlaArg: 4.811 ± 0.039	7.518AlaSer: 7.518 ± 0.049	4.863AlaThr: 4.863 ± 0.043	4.32AlaVal: 4.32 ± 0.033	0.935AlaTrp: 0.935 ± 0.016	1.741AlaTyr: 1.741 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.847CysAla: 0.847 ± 0.014	0.26CysCys: 0.26 ± 0.009	0.612CysAsp: 0.612 ± 0.011	0.566CysGlu: 0.566 ± 0.011	0.604CysPhe: 0.604 ± 0.011	0.958CysGly: 0.958 ± 0.016	0.408CysHis: 0.408 ± 0.01	0.556CysIle: 0.556 ± 0.011	0.629CysLys: 0.629 ± 0.012	1.346CysLeu: 1.346 ± 0.022	0.242CysMet: 0.242 ± 0.007	0.455CysAsn: 0.455 ± 0.011	1.005CysPro: 1.005 ± 0.016	0.604CysGln: 0.604 ± 0.013	0.734CysArg: 0.734 ± 0.015	1.126CysSer: 1.126 ± 0.018	0.636CysThr: 0.636 ± 0.012	0.656CysVal: 0.656 ± 0.013	0.219CysTrp: 0.219 ± 0.007	0.384CysTyr: 0.384 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.727AspAla: 3.727 ± 0.035	0.709AspCys: 0.709 ± 0.014	3.864AspAsp: 3.864 ± 0.047	3.968AspGlu: 3.968 ± 0.041	2.025AspPhe: 2.025 ± 0.023	3.614AspGly: 3.614 ± 0.032	1.576AspHis: 1.576 ± 0.02	2.318AspIle: 2.318 ± 0.024	2.423AspLys: 2.423 ± 0.031	5.287AspLeu: 5.287 ± 0.038	0.922AspMet: 0.922 ± 0.015	1.917AspAsn: 1.917 ± 0.022	3.985AspPro: 3.985 ± 0.031	2.683AspGln: 2.683 ± 0.023	2.984AspArg: 2.984 ± 0.03	4.358AspSer: 4.358 ± 0.035	2.399AspThr: 2.399 ± 0.024	2.761AspVal: 2.761 ± 0.026	0.859AspTrp: 0.859 ± 0.015	1.329AspTyr: 1.329 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.724GluAla: 4.724 ± 0.039	0.564GluCys: 0.564 ± 0.011	3.831GluAsp: 3.831 ± 0.031	5.132GluGlu: 5.132 ± 0.055	1.906GluPhe: 1.906 ± 0.019	3.026GluGly: 3.026 ± 0.033	1.29GluHis: 1.29 ± 0.017	3.043GluIle: 3.043 ± 0.03	3.184GluLys: 3.184 ± 0.035	5.442GluLeu: 5.442 ± 0.039	1.176GluMet: 1.176 ± 0.015	2.142GluAsn: 2.142 ± 0.024	2.972GluPro: 2.972 ± 0.029	2.447GluGln: 2.447 ± 0.026	3.272GluArg: 3.272 ± 0.03	4.067GluSer: 4.067 ± 0.035	2.932GluThr: 2.932 ± 0.03	3.066GluVal: 3.066 ± 0.031	0.762GluTrp: 0.762 ± 0.013	1.283GluTyr: 1.283 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.464PheAla: 2.464 ± 0.027	0.603PheCys: 0.603 ± 0.013	2.251PheAsp: 2.251 ± 0.024	2.03PheGlu: 2.03 ± 0.024	1.54PhePhe: 1.54 ± 0.02	2.558PheGly: 2.558 ± 0.03	0.915PheHis: 0.915 ± 0.014	1.769PheIle: 1.769 ± 0.022	2.012PheLys: 2.012 ± 0.022	3.466PheLeu: 3.466 ± 0.034	0.673PheMet: 0.673 ± 0.014	1.589PheAsn: 1.589 ± 0.022	2.01PhePro: 2.01 ± 0.024	1.545PheGln: 1.545 ± 0.02	1.869PheArg: 1.869 ± 0.023	3.08PheSer: 3.08 ± 0.029	1.931PheThr: 1.931 ± 0.019	2.118PheVal: 2.118 ± 0.026	0.555PheTrp: 0.555 ± 0.012	0.952PheTyr: 0.952 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.397GlyAla: 4.397 ± 0.041	0.889GlyCys: 0.889 ± 0.014	2.761GlyAsp: 2.761 ± 0.026	2.888GlyGlu: 2.888 ± 0.031	2.534GlyPhe: 2.534 ± 0.027	4.931GlyGly: 4.931 ± 0.072	1.67GlyHis: 1.67 ± 0.022	2.978GlyIle: 2.978 ± 0.032	3.272GlyLys: 3.272 ± 0.035	5.794GlyLeu: 5.794 ± 0.044	1.227GlyMet: 1.227 ± 0.019	2.148GlyAsn: 2.148 ± 0.025	3.838GlyPro: 3.838 ± 0.038	2.548GlyGln: 2.548 ± 0.027	3.587GlyArg: 3.587 ± 0.034	5.53GlySer: 5.53 ± 0.05	3.507GlyThr: 3.507 ± 0.03	3.283GlyVal: 3.283 ± 0.034	0.928GlyTrp: 0.928 ± 0.016	1.641GlyTyr: 1.641 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.768HisAla: 1.768 ± 0.024	0.381HisCys: 0.381 ± 0.01	1.183HisAsp: 1.183 ± 0.017	1.236HisGlu: 1.236 ± 0.019	1.03HisPhe: 1.03 ± 0.013	1.431HisGly: 1.431 ± 0.017	1.453HisHis: 1.453 ± 0.027	1.183HisIle: 1.183 ± 0.018	1.119HisLys: 1.119 ± 0.017	2.817HisLeu: 2.817 ± 0.026	0.458HisMet: 0.458 ± 0.01	0.936HisAsn: 0.936 ± 0.013	2.714HisPro: 2.714 ± 0.027	1.738HisGln: 1.738 ± 0.025	1.718HisArg: 1.718 ± 0.019	2.476HisSer: 2.476 ± 0.026	1.35HisThr: 1.35 ± 0.019	1.316HisVal: 1.316 ± 0.019	0.352HisTrp: 0.352 ± 0.01	0.659HisTyr: 0.659 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.461IleAla: 3.461 ± 0.029	0.779IleCys: 0.779 ± 0.013	2.964IleAsp: 2.964 ± 0.025	2.809IleGlu: 2.809 ± 0.032	1.856IlePhe: 1.856 ± 0.024	2.892IleGly: 2.892 ± 0.026	1.352IleHis: 1.352 ± 0.019	2.446IleIle: 2.446 ± 0.024	2.763IleLys: 2.763 ± 0.028	4.661IleLeu: 4.661 ± 0.039	0.861IleMet: 0.861 ± 0.013	2.19IleAsn: 2.19 ± 0.023	3.391IlePro: 3.391 ± 0.033	2.212IleGln: 2.212 ± 0.023	2.792IleArg: 2.792 ± 0.025	4.239IleSer: 4.239 ± 0.031	2.699IleThr: 2.699 ± 0.028	2.681IleVal: 2.681 ± 0.027	0.614IleTrp: 0.614 ± 0.013	1.165IleTyr: 1.165 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.576LysAla: 4.576 ± 0.041	0.544LysCys: 0.544 ± 0.013	2.794LysAsp: 2.794 ± 0.03	3.294LysGlu: 3.294 ± 0.03	1.783LysPhe: 1.783 ± 0.021	2.713LysGly: 2.713 ± 0.03	1.303LysHis: 1.303 ± 0.017	2.834LysIle: 2.834 ± 0.026	3.974LysLys: 3.974 ± 0.042	5.06LysLeu: 5.06 ± 0.038	1.115LysMet: 1.115 ± 0.016	2.182LysAsn: 2.182 ± 0.025	3.575LysPro: 3.575 ± 0.032	2.217LysGln: 2.217 ± 0.024	3.358LysArg: 3.358 ± 0.031	4.183LysSer: 4.183 ± 0.034	3.372LysThr: 3.372 ± 0.033	2.71LysVal: 2.71 ± 0.028	0.667LysTrp: 0.667 ± 0.012	1.266LysTyr: 1.266 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.277LeuAla: 8.277 ± 0.053	1.263LeuCys: 1.263 ± 0.019	5.386LeuAsp: 5.386 ± 0.039	5.349LeuGlu: 5.349 ± 0.038	3.336LeuPhe: 3.336 ± 0.036	5.541LeuGly: 5.541 ± 0.042	2.348LeuHis: 2.348 ± 0.023	4.711LeuIle: 4.711 ± 0.035	5.334LeuLys: 5.334 ± 0.036	8.882LeuLeu: 8.882 ± 0.063	1.823LeuMet: 1.823 ± 0.021	3.847LeuAsn: 3.847 ± 0.028	6.501LeuPro: 6.501 ± 0.043	3.834LeuGln: 3.834 ± 0.033	5.235LeuArg: 5.235 ± 0.036	8.331LeuSer: 8.331 ± 0.056	5.273LeuThr: 5.273 ± 0.039	5.406LeuVal: 5.406 ± 0.035	1.001LeuTrp: 1.001 ± 0.02	2.019LeuTyr: 2.019 ± 0.022	0.001LeuXaa: 0.001 ± 0.0
Met	1.889MetAla: 1.889 ± 0.022	0.217MetCys: 0.217 ± 0.007	1.131MetAsp: 1.131 ± 0.016	1.1MetGlu: 1.1 ± 0.015	0.675MetPhe: 0.675 ± 0.012	1.131MetGly: 1.131 ± 0.017	0.369MetHis: 0.369 ± 0.009	1.081MetIle: 1.081 ± 0.014	1.133MetLys: 1.133 ± 0.015	1.607MetLeu: 1.607 ± 0.021	0.518MetMet: 0.518 ± 0.012	0.819MetAsn: 0.819 ± 0.015	1.009MetPro: 1.009 ± 0.016	0.618MetGln: 0.618 ± 0.011	0.958MetArg: 0.958 ± 0.016	1.658MetSer: 1.658 ± 0.018	1.113MetThr: 1.113 ± 0.014	1.162MetVal: 1.162 ± 0.014	0.21MetTrp: 0.21 ± 0.006	0.428MetTyr: 0.428 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.78AsnAla: 2.78 ± 0.031	0.571AsnCys: 0.571 ± 0.012	1.87AsnAsp: 1.87 ± 0.019	2.021AsnGlu: 2.021 ± 0.023	1.507AsnPhe: 1.507 ± 0.019	2.6AsnGly: 2.6 ± 0.032	1.36AsnHis: 1.36 ± 0.017	1.805AsnIle: 1.805 ± 0.023	2.111AsnLys: 2.111 ± 0.028	3.954AsnLeu: 3.954 ± 0.032	0.703AsnMet: 0.703 ± 0.013	2.114AsnAsn: 2.114 ± 0.032	3.597AsnPro: 3.597 ± 0.033	2.305AsnGln: 2.305 ± 0.026	2.268AsnArg: 2.268 ± 0.022	3.727AsnSer: 3.727 ± 0.033	2.28AsnThr: 2.28 ± 0.026	1.947AsnVal: 1.947 ± 0.021	0.55AsnTrp: 0.55 ± 0.011	1.001AsnTyr: 1.001 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.15ProAla: 7.15 ± 0.059	0.673ProCys: 0.673 ± 0.015	3.502ProAsp: 3.502 ± 0.028	3.586ProGlu: 3.586 ± 0.031	2.169ProPhe: 2.169 ± 0.025	4.039ProGly: 4.039 ± 0.038	1.881ProHis: 1.881 ± 0.023	3.284ProIle: 3.284 ± 0.03	3.312ProLys: 3.312 ± 0.026	5.727ProLeu: 5.727 ± 0.046	1.08ProMet: 1.08 ± 0.016	3.042ProAsn: 3.042 ± 0.03	7.586ProPro: 7.586 ± 0.09	3.0ProGln: 3.0 ± 0.032	3.611ProArg: 3.611 ± 0.032	8.367ProSer: 8.367 ± 0.071	5.142ProThr: 5.142 ± 0.039	3.68ProVal: 3.68 ± 0.032	0.603ProTrp: 0.603 ± 0.011	1.292ProTyr: 1.292 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	4.152GlnAla: 4.152 ± 0.034	0.431GlnCys: 0.431 ± 0.011	2.217GlnAsp: 2.217 ± 0.023	2.541GlnGlu: 2.541 ± 0.027	1.42GlnPhe: 1.42 ± 0.019	2.094GlnGly: 2.094 ± 0.024	1.328GlnHis: 1.328 ± 0.019	2.261GlnIle: 2.261 ± 0.024	2.251GlnLys: 2.251 ± 0.022	4.474GlnLeu: 4.474 ± 0.037	0.888GlnMet: 0.888 ± 0.015	1.686GlnAsn: 1.686 ± 0.021	3.676GlnPro: 3.676 ± 0.038	3.194GlnGln: 3.194 ± 0.078	2.41GlnArg: 2.41 ± 0.025	3.95GlnSer: 3.95 ± 0.033	2.698GlnThr: 2.698 ± 0.024	2.328GlnVal: 2.328 ± 0.022	0.532GlnTrp: 0.532 ± 0.011	0.919GlnTyr: 0.919 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.486ArgAla: 4.486 ± 0.038	0.74ArgCys: 0.74 ± 0.013	2.61ArgAsp: 2.61 ± 0.026	2.875ArgGlu: 2.875 ± 0.03	2.152ArgPhe: 2.152 ± 0.021	2.993ArgGly: 2.993 ± 0.03	1.475ArgHis: 1.475 ± 0.019	2.829ArgIle: 2.829 ± 0.022	3.384ArgLys: 3.384 ± 0.031	5.73ArgLeu: 5.73 ± 0.036	1.217ArgMet: 1.217 ± 0.017	2.156ArgAsn: 2.156 ± 0.021	4.263ArgPro: 4.263 ± 0.038	2.522ArgGln: 2.522 ± 0.026	4.34ArgArg: 4.34 ± 0.042	4.995ArgSer: 4.995 ± 0.044	3.355ArgThr: 3.355 ± 0.03	2.874ArgVal: 2.874 ± 0.025	0.841ArgTrp: 0.841 ± 0.015	1.388ArgTyr: 1.388 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.366SerAla: 7.366 ± 0.052	1.124SerCys: 1.124 ± 0.02	4.437SerAsp: 4.437 ± 0.043	4.092SerGlu: 4.092 ± 0.035	3.367SerPhe: 3.367 ± 0.03	5.302SerGly: 5.302 ± 0.039	2.447SerHis: 2.447 ± 0.025	4.317SerIle: 4.317 ± 0.038	4.578SerLys: 4.578 ± 0.035	8.167SerLeu: 8.167 ± 0.058	1.594SerMet: 1.594 ± 0.02	4.038SerAsn: 4.038 ± 0.041	6.828SerPro: 6.828 ± 0.058	4.092SerGln: 4.092 ± 0.037	5.092SerArg: 5.092 ± 0.04	11.788SerSer: 11.788 ± 0.112	6.465SerThr: 6.465 ± 0.05	4.297SerVal: 4.297 ± 0.033	0.985SerTrp: 0.985 ± 0.014	1.911SerTyr: 1.911 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	4.895ThrAla: 4.895 ± 0.042	0.765ThrCys: 0.765 ± 0.012	2.776ThrAsp: 2.776 ± 0.024	2.748ThrGlu: 2.748 ± 0.026	2.072ThrPhe: 2.072 ± 0.024	3.741ThrGly: 3.741 ± 0.037	1.588ThrHis: 1.588 ± 0.021	3.003ThrIle: 3.003 ± 0.025	2.921ThrLys: 2.921 ± 0.027	5.301ThrLeu: 5.301 ± 0.033	1.013ThrMet: 1.013 ± 0.015	2.633ThrAsn: 2.633 ± 0.029	4.777ThrPro: 4.777 ± 0.044	2.45ThrGln: 2.45 ± 0.024	3.353ThrArg: 3.353 ± 0.027	5.878ThrSer: 5.878 ± 0.045	4.636ThrThr: 4.636 ± 0.047	3.002ThrVal: 3.002 ± 0.024	0.731ThrTrp: 0.731 ± 0.014	1.26ThrTyr: 1.26 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.315ValAla: 4.315 ± 0.035	0.755ValCys: 0.755 ± 0.014	3.259ValAsp: 3.259 ± 0.028	3.354ValGlu: 3.354 ± 0.03	1.964ValPhe: 1.964 ± 0.021	3.278ValGly: 3.278 ± 0.034	1.327ValHis: 1.327 ± 0.02	2.638ValIle: 2.638 ± 0.025	2.936ValLys: 2.936 ± 0.026	4.939ValLeu: 4.939 ± 0.037	1.0ValMet: 1.0 ± 0.016	2.176ValAsn: 2.176 ± 0.024	3.356ValPro: 3.356 ± 0.03	2.161ValGln: 2.161 ± 0.022	2.77ValArg: 2.77 ± 0.025	4.227ValSer: 4.227 ± 0.031	2.888ValThr: 2.888 ± 0.024	3.378ValVal: 3.378 ± 0.031	0.788ValTrp: 0.788 ± 0.013	1.353ValTyr: 1.353 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	0.962TrpAla: 0.962 ± 0.014	0.173TrpCys: 0.173 ± 0.005	0.769TrpAsp: 0.769 ± 0.014	0.789TrpGlu: 0.789 ± 0.014	0.425TrpPhe: 0.425 ± 0.011	0.691TrpGly: 0.691 ± 0.012	0.3TrpHis: 0.3 ± 0.008	0.736TrpIle: 0.736 ± 0.014	0.844TrpLys: 0.844 ± 0.014	1.237TrpLeu: 1.237 ± 0.019	0.296TrpMet: 0.296 ± 0.008	0.663TrpAsn: 0.663 ± 0.013	0.615TrpPro: 0.615 ± 0.01	0.494TrpGln: 0.494 ± 0.011	0.705TrpArg: 0.705 ± 0.013	0.962TrpSer: 0.962 ± 0.014	0.793TrpThr: 0.793 ± 0.016	0.717TrpVal: 0.717 ± 0.014	0.215TrpTrp: 0.215 ± 0.007	0.294TrpTyr: 0.294 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.518TyrAla: 1.518 ± 0.018	0.379TyrCys: 0.379 ± 0.009	1.265TyrAsp: 1.265 ± 0.019	1.141TyrGlu: 1.141 ± 0.017	0.934TyrPhe: 0.934 ± 0.016	1.512TyrGly: 1.512 ± 0.02	0.775TyrHis: 0.775 ± 0.012	1.068TyrIle: 1.068 ± 0.016	1.087TyrLys: 1.087 ± 0.017	2.601TyrLeu: 2.601 ± 0.026	0.462TyrMet: 0.462 ± 0.01	1.055TyrAsn: 1.055 ± 0.015	1.461TyrPro: 1.461 ± 0.021	1.141TyrGln: 1.141 ± 0.017	1.357TyrArg: 1.357 ± 0.017	1.827TyrSer: 1.827 ± 0.022	1.211TyrThr: 1.211 ± 0.017	1.157TyrVal: 1.157 ± 0.017	0.336TyrTrp: 0.336 ± 0.008	0.703TyrTyr: 0.703 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.096XaaXaa: 0.096 ± 0.024

Statistics based on 11515 proteins (4624077 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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