Amino acid dipepetide frequency for Dragonfly associated cyclovirus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.036AlaAla: 6.036 ± 4.577
2.012AlaCys: 2.012 ± 1.526
2.012AlaAsp: 2.012 ± 1.207
2.012AlaGlu: 2.012 ± 1.526
2.012AlaPhe: 2.012 ± 1.526
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
4.024AlaIle: 4.024 ± 0.319
2.012AlaLys: 2.012 ± 1.526
2.012AlaLeu: 2.012 ± 1.207
0.0AlaMet: 0.0 ± 0.0
4.024AlaAsn: 4.024 ± 0.319
8.048AlaPro: 8.048 ± 0.638
4.024AlaGln: 4.024 ± 2.414
4.024AlaArg: 4.024 ± 0.319
2.012AlaSer: 2.012 ± 1.526
8.048AlaThr: 8.048 ± 3.37
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.012CysAsp: 2.012 ± 1.207
0.0CysGlu: 0.0 ± 0.0
2.012CysPhe: 2.012 ± 1.207
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
4.024CysLys: 4.024 ± 2.414
2.012CysLeu: 2.012 ± 1.526
0.0CysMet: 0.0 ± 0.0
6.036CysAsn: 6.036 ± 3.62
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.012CysSer: 2.012 ± 1.207
2.012CysThr: 2.012 ± 1.207
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.012AspAla: 2.012 ± 1.207
0.0AspCys: 0.0 ± 0.0
2.012AspAsp: 2.012 ± 1.207
6.036AspGlu: 6.036 ± 3.62
6.036AspPhe: 6.036 ± 0.888
4.024AspGly: 4.024 ± 2.414
0.0AspHis: 0.0 ± 0.0
2.012AspIle: 2.012 ± 1.207
0.0AspLys: 0.0 ± 0.0
6.036AspLeu: 6.036 ± 0.888
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
6.036AspArg: 6.036 ± 1.845
2.012AspSer: 2.012 ± 1.526
4.024AspThr: 4.024 ± 2.414
2.012AspVal: 2.012 ± 1.526
2.012AspTrp: 2.012 ± 1.526
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.024GluAla: 4.024 ± 0.319
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
4.024GluGlu: 4.024 ± 2.414
6.036GluPhe: 6.036 ± 1.845
2.012GluGly: 2.012 ± 1.207
2.012GluHis: 2.012 ± 1.207
4.024GluIle: 4.024 ± 0.319
6.036GluLys: 6.036 ± 0.888
4.024GluLeu: 4.024 ± 2.414
0.0GluMet: 0.0 ± 0.0
2.012GluAsn: 2.012 ± 1.207
2.012GluPro: 2.012 ± 1.526
2.012GluGln: 2.012 ± 1.207
4.024GluArg: 4.024 ± 0.319
2.012GluSer: 2.012 ± 1.207
4.024GluThr: 4.024 ± 3.051
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.012GluTyr: 2.012 ± 1.207
0.0GluXaa: 0.0 ± 0.0
Phe
2.012PheAla: 2.012 ± 1.526
2.012PheCys: 2.012 ± 1.207
0.0PheAsp: 0.0 ± 0.0
10.06PheGlu: 10.06 ± 2.163
0.0PhePhe: 0.0 ± 0.0
4.024PheGly: 4.024 ± 0.319
0.0PheHis: 0.0 ± 0.0
6.036PheIle: 6.036 ± 0.888
6.036PheLys: 6.036 ± 1.845
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
2.012PhePro: 2.012 ± 1.526
2.012PheGln: 2.012 ± 1.526
4.024PheArg: 4.024 ± 0.319
4.024PheSer: 4.024 ± 0.319
4.024PheThr: 4.024 ± 2.414
2.012PheVal: 2.012 ± 1.526
0.0PheTrp: 0.0 ± 0.0
2.012PheTyr: 2.012 ± 1.207
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
4.024GlyGlu: 4.024 ± 0.319
2.012GlyPhe: 2.012 ± 1.526
2.012GlyGly: 2.012 ± 1.526
0.0GlyHis: 0.0 ± 0.0
4.024GlyIle: 4.024 ± 2.414
4.024GlyLys: 4.024 ± 2.414
2.012GlyLeu: 2.012 ± 1.526
0.0GlyMet: 0.0 ± 0.0
2.012GlyAsn: 2.012 ± 1.207
2.012GlyPro: 2.012 ± 1.207
4.024GlyGln: 4.024 ± 2.414
2.012GlyArg: 2.012 ± 1.526
6.036GlySer: 6.036 ± 3.62
4.024GlyThr: 4.024 ± 0.319
2.012GlyVal: 2.012 ± 1.207
2.012GlyTrp: 2.012 ± 1.207
8.048GlyTyr: 8.048 ± 2.095
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.012HisAsp: 2.012 ± 1.207
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
4.024HisIle: 4.024 ± 2.414
0.0HisLys: 0.0 ± 0.0
4.024HisLeu: 4.024 ± 2.414
0.0HisMet: 0.0 ± 0.0
2.012HisAsn: 2.012 ± 1.207
4.024HisPro: 4.024 ± 2.414
4.024HisGln: 4.024 ± 0.319
2.012HisArg: 2.012 ± 1.526
0.0HisSer: 0.0 ± 0.0
2.012HisThr: 2.012 ± 1.207
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.024IleAla: 4.024 ± 2.414
0.0IleCys: 0.0 ± 0.0
6.036IleAsp: 6.036 ± 1.845
4.024IleGlu: 4.024 ± 2.414
6.036IlePhe: 6.036 ± 0.888
2.012IleGly: 2.012 ± 1.207
4.024IleHis: 4.024 ± 2.414
2.012IleIle: 2.012 ± 1.207
6.036IleLys: 6.036 ± 3.62
0.0IleLeu: 0.0 ± 0.0
2.012IleMet: 2.012 ± 1.067
2.012IleAsn: 2.012 ± 1.526
2.012IlePro: 2.012 ± 1.526
4.024IleGln: 4.024 ± 2.414
2.012IleArg: 2.012 ± 1.207
2.012IleSer: 2.012 ± 1.526
4.024IleThr: 4.024 ± 2.414
4.024IleVal: 4.024 ± 3.051
2.012IleTrp: 2.012 ± 1.207
2.012IleTyr: 2.012 ± 1.207
0.0IleXaa: 0.0 ± 0.0
Lys
2.012LysAla: 2.012 ± 1.207
2.012LysCys: 2.012 ± 1.207
2.012LysAsp: 2.012 ± 1.207
4.024LysGlu: 4.024 ± 2.414
4.024LysPhe: 4.024 ± 2.414
6.036LysGly: 6.036 ± 0.888
4.024LysHis: 4.024 ± 2.414
0.0LysIle: 0.0 ± 0.0
2.012LysLys: 2.012 ± 1.207
2.012LysLeu: 2.012 ± 1.526
0.0LysMet: 0.0 ± 0.0
2.012LysAsn: 2.012 ± 1.526
8.048LysPro: 8.048 ± 0.638
0.0LysGln: 0.0 ± 0.0
4.024LysArg: 4.024 ± 0.319
6.036LysSer: 6.036 ± 3.62
2.012LysThr: 2.012 ± 1.207
10.06LysVal: 10.06 ± 2.163
0.0LysTrp: 0.0 ± 0.0
6.036LysTyr: 6.036 ± 0.888
0.0LysXaa: 0.0 ± 0.0
Leu
8.048LeuAla: 8.048 ± 2.095
0.0LeuCys: 0.0 ± 0.0
2.012LeuAsp: 2.012 ± 1.526
2.012LeuGlu: 2.012 ± 1.207
0.0LeuPhe: 0.0 ± 0.0
0.0LeuGly: 0.0 ± 0.0
2.012LeuHis: 2.012 ± 1.207
2.012LeuIle: 2.012 ± 1.526
4.024LeuLys: 4.024 ± 2.414
6.036LeuLeu: 6.036 ± 0.888
0.0LeuMet: 0.0 ± 0.0
10.06LeuAsn: 10.06 ± 4.896
0.0LeuPro: 0.0 ± 0.0
4.024LeuGln: 4.024 ± 2.414
8.048LeuArg: 8.048 ± 6.103
4.024LeuSer: 4.024 ± 0.319
2.012LeuThr: 2.012 ± 1.526
2.012LeuVal: 2.012 ± 1.207
0.0LeuTrp: 0.0 ± 0.0
8.048LeuTyr: 8.048 ± 3.37
0.0LeuXaa: 0.0 ± 0.0
Met
2.012MetAla: 2.012 ± 1.526
2.012MetCys: 2.012 ± 1.207
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.012MetArg: 2.012 ± 1.207
4.024MetSer: 4.024 ± 0.319
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
2.012AsnAsp: 2.012 ± 1.526
2.012AsnGlu: 2.012 ± 1.207
2.012AsnPhe: 2.012 ± 1.207
2.012AsnGly: 2.012 ± 1.207
0.0AsnHis: 0.0 ± 0.0
2.012AsnIle: 2.012 ± 1.207
6.036AsnLys: 6.036 ± 0.888
6.036AsnLeu: 6.036 ± 0.888
0.0AsnMet: 0.0 ± 0.0
4.024AsnAsn: 4.024 ± 0.319
0.0AsnPro: 0.0 ± 0.0
4.024AsnGln: 4.024 ± 3.051
4.024AsnArg: 4.024 ± 0.319
8.048AsnSer: 8.048 ± 0.638
4.024AsnThr: 4.024 ± 0.319
6.036AsnVal: 6.036 ± 1.845
0.0AsnTrp: 0.0 ± 0.0
2.012AsnTyr: 2.012 ± 1.207
0.0AsnXaa: 0.0 ± 0.0
Pro
4.024ProAla: 4.024 ± 3.051
0.0ProCys: 0.0 ± 0.0
4.024ProAsp: 4.024 ± 3.051
2.012ProGlu: 2.012 ± 1.526
0.0ProPhe: 0.0 ± 0.0
4.024ProGly: 4.024 ± 0.319
4.024ProHis: 4.024 ± 0.319
4.024ProIle: 4.024 ± 2.414
0.0ProLys: 0.0 ± 0.0
4.024ProLeu: 4.024 ± 3.051
2.012ProMet: 2.012 ± 1.207
0.0ProAsn: 0.0 ± 0.0
6.036ProPro: 6.036 ± 1.845
0.0ProGln: 0.0 ± 0.0
4.024ProArg: 4.024 ± 2.414
4.024ProSer: 4.024 ± 3.051
6.036ProThr: 6.036 ± 0.888
2.012ProVal: 2.012 ± 1.526
0.0ProTrp: 0.0 ± 0.0
4.024ProTyr: 4.024 ± 0.319
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.012GlnAsp: 2.012 ± 1.207
2.012GlnGlu: 2.012 ± 1.207
0.0GlnPhe: 0.0 ± 0.0
2.012GlnGly: 2.012 ± 1.207
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
6.036GlnAsn: 6.036 ± 1.845
0.0GlnPro: 0.0 ± 0.0
2.012GlnGln: 2.012 ± 1.207
4.024GlnArg: 4.024 ± 0.319
4.024GlnSer: 4.024 ± 2.414
2.012GlnThr: 2.012 ± 1.207
6.036GlnVal: 6.036 ± 1.845
2.012GlnTrp: 2.012 ± 1.207
4.024GlnTyr: 4.024 ± 0.319
0.0GlnXaa: 0.0 ± 0.0
Arg
4.024ArgAla: 4.024 ± 0.319
2.012ArgCys: 2.012 ± 1.207
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
8.048ArgPhe: 8.048 ± 3.37
8.048ArgGly: 8.048 ± 2.095
0.0ArgHis: 0.0 ± 0.0
4.024ArgIle: 4.024 ± 0.319
4.024ArgLys: 4.024 ± 0.319
8.048ArgLeu: 8.048 ± 6.103
2.012ArgMet: 2.012 ± 1.526
6.036ArgAsn: 6.036 ± 0.888
4.024ArgPro: 4.024 ± 3.051
0.0ArgGln: 0.0 ± 0.0
18.109ArgArg: 18.109 ± 8.266
4.024ArgSer: 4.024 ± 3.051
6.036ArgThr: 6.036 ± 1.845
4.024ArgVal: 4.024 ± 3.051
0.0ArgTrp: 0.0 ± 0.0
6.036ArgTyr: 6.036 ± 0.888
0.0ArgXaa: 0.0 ± 0.0
Ser
4.024SerAla: 4.024 ± 3.051
0.0SerCys: 0.0 ± 0.0
2.012SerAsp: 2.012 ± 1.207
2.012SerGlu: 2.012 ± 1.526
8.048SerPhe: 8.048 ± 3.37
4.024SerGly: 4.024 ± 2.414
2.012SerHis: 2.012 ± 1.207
6.036SerIle: 6.036 ± 0.888
8.048SerLys: 8.048 ± 2.095
6.036SerLeu: 6.036 ± 1.845
0.0SerMet: 0.0 ± 0.96
4.024SerAsn: 4.024 ± 0.319
2.012SerPro: 2.012 ± 1.526
0.0SerGln: 0.0 ± 0.0
6.036SerArg: 6.036 ± 1.845
4.024SerSer: 4.024 ± 3.051
6.036SerThr: 6.036 ± 0.888
2.012SerVal: 2.012 ± 1.526
0.0SerTrp: 0.0 ± 0.0
2.012SerTyr: 2.012 ± 1.207
0.0SerXaa: 0.0 ± 0.0
Thr
8.048ThrAla: 8.048 ± 3.37
2.012ThrCys: 2.012 ± 1.207
8.048ThrAsp: 8.048 ± 4.827
4.024ThrGlu: 4.024 ± 0.319
0.0ThrPhe: 0.0 ± 0.0
4.024ThrGly: 4.024 ± 3.051
0.0ThrHis: 0.0 ± 0.0
4.024ThrIle: 4.024 ± 0.319
0.0ThrLys: 0.0 ± 0.0
4.024ThrLeu: 4.024 ± 2.414
0.0ThrMet: 0.0 ± 0.0
2.012ThrAsn: 2.012 ± 1.207
8.048ThrPro: 8.048 ± 0.638
2.012ThrGln: 2.012 ± 1.526
2.012ThrArg: 2.012 ± 1.526
6.036ThrSer: 6.036 ± 0.888
4.024ThrThr: 4.024 ± 2.414
4.024ThrVal: 4.024 ± 0.319
2.012ThrTrp: 2.012 ± 1.207
8.048ThrTyr: 8.048 ± 2.095
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
2.012ValAsp: 2.012 ± 1.207
2.012ValGlu: 2.012 ± 1.526
2.012ValPhe: 2.012 ± 1.526
0.0ValGly: 0.0 ± 0.0
2.012ValHis: 2.012 ± 1.207
6.036ValIle: 6.036 ± 1.845
6.036ValLys: 6.036 ± 1.845
4.024ValLeu: 4.024 ± 3.051
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
4.024ValPro: 4.024 ± 3.051
4.024ValGln: 4.024 ± 0.319
6.036ValArg: 6.036 ± 1.845
4.024ValSer: 4.024 ± 3.051
2.012ValThr: 2.012 ± 1.207
2.012ValVal: 2.012 ± 1.526
0.0ValTrp: 0.0 ± 0.0
6.036ValTyr: 6.036 ± 4.577
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.012TrpAsp: 2.012 ± 1.207
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
2.012TrpGly: 2.012 ± 1.207
0.0TrpHis: 0.0 ± 0.0
4.024TrpIle: 4.024 ± 2.414
2.012TrpLys: 2.012 ± 1.526
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.012TrpAsn: 2.012 ± 1.207
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.012TrpTrp: 2.012 ± 1.207
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.012TyrAla: 2.012 ± 1.526
8.048TyrCys: 8.048 ± 4.827
4.024TyrAsp: 4.024 ± 0.319
0.0TyrGlu: 0.0 ± 0.0
2.012TyrPhe: 2.012 ± 1.207
4.024TyrGly: 4.024 ± 2.414
4.024TyrHis: 4.024 ± 0.319
2.012TyrIle: 2.012 ± 1.207
6.036TyrLys: 6.036 ± 3.62
4.024TyrLeu: 4.024 ± 0.319
2.012TyrMet: 2.012 ± 1.207
0.0TyrAsn: 0.0 ± 0.0
2.012TyrPro: 2.012 ± 1.207
0.0TyrGln: 0.0 ± 0.0
6.036TyrArg: 6.036 ± 4.577
2.012TyrSer: 2.012 ± 1.526
6.036TyrThr: 6.036 ± 1.845
4.024TyrVal: 4.024 ± 3.051
2.012TyrTrp: 2.012 ± 1.207
6.036TyrTyr: 6.036 ± 3.62
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (498 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski