Amino acid dipepetide frequency for Dendrothele bispora (strain CBS 962.96)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.01AlaAla: 6.01 ± 0.026	1.007AlaCys: 1.007 ± 0.01	3.364AlaAsp: 3.364 ± 0.019	3.937AlaGlu: 3.937 ± 0.022	3.055AlaPhe: 3.055 ± 0.016	4.561AlaGly: 4.561 ± 0.024	1.629AlaHis: 1.629 ± 0.013	3.871AlaIle: 3.871 ± 0.022	3.397AlaLys: 3.397 ± 0.018	6.86AlaLeu: 6.86 ± 0.029	1.615AlaMet: 1.615 ± 0.012	2.661AlaAsn: 2.661 ± 0.016	3.863AlaPro: 3.863 ± 0.024	2.868AlaGln: 2.868 ± 0.019	4.056AlaArg: 4.056 ± 0.02	6.411AlaSer: 6.411 ± 0.03	4.548AlaThr: 4.548 ± 0.023	4.594AlaVal: 4.594 ± 0.022	1.046AlaTrp: 1.046 ± 0.01	2.0AlaTyr: 2.0 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	0.853CysAla: 0.853 ± 0.01	0.324CysCys: 0.324 ± 0.006	0.683CysAsp: 0.683 ± 0.008	0.614CysGlu: 0.614 ± 0.008	0.617CysPhe: 0.617 ± 0.008	0.858CysGly: 0.858 ± 0.01	0.397CysHis: 0.397 ± 0.006	0.78CysIle: 0.78 ± 0.009	0.57CysLys: 0.57 ± 0.007	1.444CysLeu: 1.444 ± 0.011	0.306CysMet: 0.306 ± 0.006	0.512CysAsn: 0.512 ± 0.007	0.826CysPro: 0.826 ± 0.011	0.514CysGln: 0.514 ± 0.007	0.837CysArg: 0.837 ± 0.01	1.135CysSer: 1.135 ± 0.012	0.811CysThr: 0.811 ± 0.009	0.847CysVal: 0.847 ± 0.009	0.228CysTrp: 0.228 ± 0.005	0.406CysTyr: 0.406 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	3.867AspAla: 3.867 ± 0.02	0.696AspCys: 0.696 ± 0.007	4.007AspAsp: 4.007 ± 0.027	4.302AspGlu: 4.302 ± 0.026	2.291AspPhe: 2.291 ± 0.014	3.875AspGly: 3.875 ± 0.024	1.314AspHis: 1.314 ± 0.013	3.33AspIle: 3.33 ± 0.019	2.419AspLys: 2.419 ± 0.017	5.046AspLeu: 5.046 ± 0.021	1.237AspMet: 1.237 ± 0.011	2.11AspAsn: 2.11 ± 0.014	3.405AspPro: 3.405 ± 0.022	1.886AspGln: 1.886 ± 0.013	2.792AspArg: 2.792 ± 0.018	4.638AspSer: 4.638 ± 0.025	3.045AspThr: 3.045 ± 0.016	3.86AspVal: 3.86 ± 0.139	0.923AspTrp: 0.923 ± 0.01	1.518AspTyr: 1.518 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.331GluAla: 4.331 ± 0.025	0.719GluCys: 0.719 ± 0.009	4.221GluAsp: 4.221 ± 0.027	5.795GluGlu: 5.795 ± 0.05	1.962GluPhe: 1.962 ± 0.014	3.721GluGly: 3.721 ± 0.024	1.379GluHis: 1.379 ± 0.011	3.16GluIle: 3.16 ± 0.017	3.598GluLys: 3.598 ± 0.024	5.224GluLeu: 5.224 ± 0.024	1.475GluMet: 1.475 ± 0.012	2.431GluAsn: 2.431 ± 0.016	2.473GluPro: 2.473 ± 0.016	2.221GluGln: 2.221 ± 0.015	3.84GluArg: 3.84 ± 0.024	4.198GluSer: 4.198 ± 0.021	3.243GluThr: 3.243 ± 0.018	3.732GluVal: 3.732 ± 0.138	0.999GluTrp: 0.999 ± 0.011	1.635GluTyr: 1.635 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	2.715PheAla: 2.715 ± 0.016	0.645PheCys: 0.645 ± 0.008	2.385PheAsp: 2.385 ± 0.016	2.231PheGlu: 2.231 ± 0.016	1.864PhePhe: 1.864 ± 0.014	2.819PheGly: 2.819 ± 0.019	1.108PheHis: 1.108 ± 0.01	2.055PheIle: 2.055 ± 0.015	1.696PheLys: 1.696 ± 0.013	3.95PheLeu: 3.95 ± 0.021	0.834PheMet: 0.834 ± 0.008	1.589PheAsn: 1.589 ± 0.013	2.252PhePro: 2.252 ± 0.015	1.49PheGln: 1.49 ± 0.013	2.102PheArg: 2.102 ± 0.015	3.516PheSer: 3.516 ± 0.022	2.304PheThr: 2.304 ± 0.016	2.572PheVal: 2.572 ± 0.016	0.649PheTrp: 0.649 ± 0.008	1.154PheTyr: 1.154 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.089GlyAla: 4.089 ± 0.023	0.853GlyCys: 0.853 ± 0.01	3.462GlyAsp: 3.462 ± 0.022	3.504GlyGlu: 3.504 ± 0.02	2.568GlyPhe: 2.568 ± 0.017	5.315GlyGly: 5.315 ± 0.046	1.771GlyHis: 1.771 ± 0.015	3.369GlyIle: 3.369 ± 0.019	3.499GlyLys: 3.499 ± 0.021	5.444GlyLeu: 5.444 ± 0.024	1.485GlyMet: 1.485 ± 0.013	2.674GlyAsn: 2.674 ± 0.017	3.037GlyPro: 3.037 ± 0.021	2.298GlyGln: 2.298 ± 0.015	3.801GlyArg: 3.801 ± 0.019	5.81GlySer: 5.81 ± 0.03	3.966GlyThr: 3.966 ± 0.022	4.102GlyVal: 4.102 ± 0.021	1.085GlyTrp: 1.085 ± 0.01	1.874GlyTyr: 1.874 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.712HisAla: 1.712 ± 0.012	0.404HisCys: 0.404 ± 0.006	1.319HisAsp: 1.319 ± 0.011	1.245HisGlu: 1.245 ± 0.009	1.114HisPhe: 1.114 ± 0.01	1.544HisGly: 1.544 ± 0.013	0.953HisHis: 0.953 ± 0.014	1.382HisIle: 1.382 ± 0.013	0.938HisLys: 0.938 ± 0.009	2.569HisLeu: 2.569 ± 0.017	0.462HisMet: 0.462 ± 0.007	0.913HisAsn: 0.913 ± 0.009	1.823HisPro: 1.823 ± 0.015	1.009HisGln: 1.009 ± 0.01	1.6HisArg: 1.6 ± 0.014	2.218HisSer: 2.218 ± 0.016	1.45HisThr: 1.45 ± 0.012	1.548HisVal: 1.548 ± 0.012	0.411HisTrp: 0.411 ± 0.006	0.783HisTyr: 0.783 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.737IleAla: 3.737 ± 0.021	0.828IleCys: 0.828 ± 0.008	2.961IleAsp: 2.961 ± 0.014	2.827IleGlu: 2.827 ± 0.016	2.153IlePhe: 2.153 ± 0.015	3.091IleGly: 3.091 ± 0.021	1.404IleHis: 1.404 ± 0.013	2.731IleIle: 2.731 ± 0.018	2.197IleLys: 2.197 ± 0.013	4.992IleLeu: 4.992 ± 0.027	1.009IleMet: 1.009 ± 0.01	1.97IleAsn: 1.97 ± 0.015	3.588IlePro: 3.588 ± 0.019	2.085IleGln: 2.085 ± 0.014	2.897IleArg: 2.897 ± 0.014	4.318IleSer: 4.318 ± 0.021	2.976IleThr: 2.976 ± 0.017	3.361IleVal: 3.361 ± 0.019	0.829IleTrp: 0.829 ± 0.01	1.518IleTyr: 1.518 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	3.811LysAla: 3.811 ± 0.019	0.593LysCys: 0.593 ± 0.007	2.765LysAsp: 2.765 ± 0.016	3.593LysGlu: 3.593 ± 0.026	1.619LysPhe: 1.619 ± 0.012	2.957LysGly: 2.957 ± 0.02	1.171LysHis: 1.171 ± 0.01	2.365LysIle: 2.365 ± 0.015	3.444LysLys: 3.444 ± 0.025	4.108LysLeu: 4.108 ± 0.022	1.057LysMet: 1.057 ± 0.01	1.957LysAsn: 1.957 ± 0.012	2.559LysPro: 2.559 ± 0.016	1.738LysGln: 1.738 ± 0.013	3.418LysArg: 3.418 ± 0.019	3.694LysSer: 3.694 ± 0.022	2.971LysThr: 2.971 ± 0.019	2.746LysVal: 2.746 ± 0.017	0.728LysTrp: 0.728 ± 0.009	1.404LysTyr: 1.404 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.689LeuAla: 6.689 ± 0.025	1.306LeuCys: 1.306 ± 0.011	5.205LeuAsp: 5.205 ± 0.022	5.506LeuGlu: 5.506 ± 0.029	3.747LeuPhe: 3.747 ± 0.022	5.699LeuGly: 5.699 ± 0.026	2.433LeuHis: 2.433 ± 0.015	4.203LeuIle: 4.203 ± 0.024	4.463LeuLys: 4.463 ± 0.021	8.562LeuLeu: 8.562 ± 0.039	1.771LeuMet: 1.771 ± 0.014	3.534LeuAsn: 3.534 ± 0.021	5.894LeuPro: 5.894 ± 0.023	3.811LeuGln: 3.811 ± 0.02	5.534LeuArg: 5.534 ± 0.027	8.185LeuSer: 8.185 ± 0.029	5.247LeuThr: 5.247 ± 0.025	5.682LeuVal: 5.682 ± 0.025	1.281LeuTrp: 1.281 ± 0.012	2.474LeuTyr: 2.474 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	1.583MetAla: 1.583 ± 0.011	0.254MetCys: 0.254 ± 0.005	1.233MetAsp: 1.233 ± 0.01	1.268MetGlu: 1.268 ± 0.011	0.848MetPhe: 0.848 ± 0.008	1.301MetGly: 1.301 ± 0.012	0.474MetHis: 0.474 ± 0.007	1.07MetIle: 1.07 ± 0.01	1.087MetLys: 1.087 ± 0.011	1.777MetLeu: 1.777 ± 0.014	0.553MetMet: 0.553 ± 0.008	0.885MetAsn: 0.885 ± 0.01	1.151MetPro: 1.151 ± 0.011	0.819MetGln: 0.819 ± 0.009	1.236MetArg: 1.236 ± 0.01	2.07MetSer: 2.07 ± 0.015	1.36MetThr: 1.36 ± 0.01	1.238MetVal: 1.238 ± 0.011	0.275MetTrp: 0.275 ± 0.005	0.593MetTyr: 0.593 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	3.162AsnAla: 3.162 ± 0.019	0.498AsnCys: 0.498 ± 0.007	2.233AsnAsp: 2.233 ± 0.013	2.138AsnGlu: 2.138 ± 0.014	1.597AsnPhe: 1.597 ± 0.013	2.828AsnGly: 2.828 ± 0.02	1.043AsnHis: 1.043 ± 0.009	2.178AsnIle: 2.178 ± 0.014	1.673AsnLys: 1.673 ± 0.012	3.699AsnLeu: 3.699 ± 0.02	0.828AsnMet: 0.828 ± 0.009	1.869AsnAsn: 1.869 ± 0.015	2.652AsnPro: 2.652 ± 0.015	1.496AsnGln: 1.496 ± 0.014	2.0AsnArg: 2.0 ± 0.014	3.436AsnSer: 3.436 ± 0.02	2.553AsnThr: 2.553 ± 0.018	2.586AsnVal: 2.586 ± 0.016	0.599AsnTrp: 0.599 ± 0.007	1.04AsnTyr: 1.04 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	4.135ProAla: 4.135 ± 0.025	0.567ProCys: 0.567 ± 0.007	3.307ProAsp: 3.307 ± 0.018	3.65ProGlu: 3.65 ± 0.019	2.253ProPhe: 2.253 ± 0.015	3.558ProGly: 3.558 ± 0.024	1.411ProHis: 1.411 ± 0.012	2.765ProIle: 2.765 ± 0.016	2.581ProLys: 2.581 ± 0.016	5.074ProLeu: 5.074 ± 0.025	0.966ProMet: 0.966 ± 0.01	2.461ProAsn: 2.461 ± 0.019	5.323ProPro: 5.323 ± 0.05	2.188ProGln: 2.188 ± 0.017	3.175ProArg: 3.175 ± 0.019	7.018ProSer: 7.018 ± 0.034	4.223ProThr: 4.223 ± 0.022	3.672ProVal: 3.672 ± 0.023	0.74ProTrp: 0.74 ± 0.008	1.53ProTyr: 1.53 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.895GlnAla: 2.895 ± 0.017	0.549GlnCys: 0.549 ± 0.008	2.048GlnAsp: 2.048 ± 0.015	2.362GlnGlu: 2.362 ± 0.017	1.381GlnPhe: 1.381 ± 0.013	2.232GlnGly: 2.232 ± 0.017	1.003GlnHis: 1.003 ± 0.009	1.966GlnIle: 1.966 ± 0.012	1.936GlnLys: 1.936 ± 0.013	3.374GlnLeu: 3.374 ± 0.02	0.853GlnMet: 0.853 ± 0.009	1.681GlnAsn: 1.681 ± 0.014	2.159GlnPro: 2.159 ± 0.017	2.001GlnGln: 2.001 ± 0.023	2.35GlnArg: 2.35 ± 0.016	3.211GlnSer: 3.211 ± 0.022	2.426GlnThr: 2.426 ± 0.017	2.302GlnVal: 2.302 ± 0.014	0.575GlnTrp: 0.575 ± 0.009	1.109GlnTyr: 1.109 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.963ArgAla: 3.963 ± 0.021	0.83ArgCys: 0.83 ± 0.009	3.149ArgAsp: 3.149 ± 0.02	3.592ArgGlu: 3.592 ± 0.023	2.262ArgPhe: 2.262 ± 0.014	3.299ArgGly: 3.299 ± 0.019	1.525ArgHis: 1.525 ± 0.011	3.037ArgIle: 3.037 ± 0.016	3.506ArgLys: 3.506 ± 0.021	5.391ArgLeu: 5.391 ± 0.023	1.328ArgMet: 1.328 ± 0.011	2.37ArgAsn: 2.37 ± 0.015	3.116ArgPro: 3.116 ± 0.017	2.258ArgGln: 2.258 ± 0.015	4.595ArgArg: 4.595 ± 0.028	4.915ArgSer: 4.915 ± 0.025	3.332ArgThr: 3.332 ± 0.018	3.581ArgVal: 3.581 ± 0.019	0.995ArgTrp: 0.995 ± 0.011	1.717ArgTyr: 1.717 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	6.027SerAla: 6.027 ± 0.026	1.066SerCys: 1.066 ± 0.012	4.789SerAsp: 4.789 ± 0.027	4.491SerGlu: 4.491 ± 0.019	3.63SerPhe: 3.63 ± 0.018	5.846SerGly: 5.846 ± 0.031	2.188SerHis: 2.188 ± 0.016	4.372SerIle: 4.372 ± 0.02	3.96SerLys: 3.96 ± 0.023	8.171SerLeu: 8.171 ± 0.032	1.785SerMet: 1.785 ± 0.012	3.669SerAsn: 3.669 ± 0.017	5.962SerPro: 5.962 ± 0.039	3.436SerGln: 3.436 ± 0.022	5.138SerArg: 5.138 ± 0.027	11.658SerSer: 11.658 ± 0.073	6.588SerThr: 6.588 ± 0.032	5.227SerVal: 5.227 ± 0.025	1.199SerTrp: 1.199 ± 0.012	2.135SerTyr: 2.135 ± 0.014	0.0SerXaa: 0.0 ± 0.0
Thr	4.436ThrAla: 4.436 ± 0.024	0.842ThrCys: 0.842 ± 0.009	2.863ThrAsp: 2.863 ± 0.016	3.013ThrGlu: 3.013 ± 0.017	2.522ThrPhe: 2.522 ± 0.016	4.013ThrGly: 4.013 ± 0.023	1.485ThrHis: 1.485 ± 0.011	3.22ThrIle: 3.22 ± 0.017	2.62ThrLys: 2.62 ± 0.018	5.758ThrLeu: 5.758 ± 0.024	1.207ThrMet: 1.207 ± 0.01	2.402ThrAsn: 2.402 ± 0.015	4.441ThrPro: 4.441 ± 0.029	2.207ThrGln: 2.207 ± 0.015	3.462ThrArg: 3.462 ± 0.018	6.422ThrSer: 6.422 ± 0.03	4.653ThrThr: 4.653 ± 0.032	3.899ThrVal: 3.899 ± 0.022	0.83ThrTrp: 0.83 ± 0.009	1.587ThrTyr: 1.587 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.414ValAla: 4.414 ± 0.021	0.89ValCys: 0.89 ± 0.009	3.969ValAsp: 3.969 ± 0.136	3.946ValGlu: 3.946 ± 0.138	2.627ValPhe: 2.627 ± 0.018	3.769ValGly: 3.769 ± 0.019	1.517ValHis: 1.517 ± 0.011	3.289ValIle: 3.289 ± 0.02	3.025ValLys: 3.025 ± 0.018	5.819ValLeu: 5.819 ± 0.026	1.327ValMet: 1.327 ± 0.012	2.518ValAsn: 2.518 ± 0.015	3.858ValPro: 3.858 ± 0.018	2.496ValGln: 2.496 ± 0.016	3.259ValArg: 3.259 ± 0.019	5.056ValSer: 5.056 ± 0.027	3.591ValThr: 3.591 ± 0.022	4.39ValVal: 4.39 ± 0.021	0.988ValTrp: 0.988 ± 0.012	1.771ValTyr: 1.771 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.003TrpAla: 1.003 ± 0.01	0.234TrpCys: 0.234 ± 0.005	0.938TrpAsp: 0.938 ± 0.011	0.876TrpGlu: 0.876 ± 0.01	0.624TrpPhe: 0.624 ± 0.008	0.863TrpGly: 0.863 ± 0.01	0.352TrpHis: 0.352 ± 0.006	0.903TrpIle: 0.903 ± 0.009	0.944TrpLys: 0.944 ± 0.009	1.286TrpLeu: 1.286 ± 0.013	0.403TrpMet: 0.403 ± 0.006	0.777TrpAsn: 0.777 ± 0.009	0.551TrpPro: 0.551 ± 0.007	0.506TrpGln: 0.506 ± 0.007	0.997TrpArg: 0.997 ± 0.009	1.195TrpSer: 1.195 ± 0.011	0.967TrpThr: 0.967 ± 0.01	0.955TrpVal: 0.955 ± 0.01	0.296TrpTrp: 0.296 ± 0.005	0.44TrpTyr: 0.44 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.921TyrAla: 1.921 ± 0.013	0.458TyrCys: 0.458 ± 0.007	1.657TyrAsp: 1.657 ± 0.013	1.466TyrGlu: 1.466 ± 0.013	1.197TyrPhe: 1.197 ± 0.012	1.858TyrGly: 1.858 ± 0.015	0.84TyrHis: 0.84 ± 0.008	1.426TyrIle: 1.426 ± 0.011	1.148TyrLys: 1.148 ± 0.01	2.679TyrLeu: 2.679 ± 0.016	0.572TyrMet: 0.572 ± 0.007	1.125TyrAsn: 1.125 ± 0.01	1.664TyrPro: 1.664 ± 0.014	1.086TyrGln: 1.086 ± 0.009	1.671TyrArg: 1.671 ± 0.013	2.236TyrSer: 2.236 ± 0.014	1.627TyrThr: 1.627 ± 0.012	1.624TyrVal: 1.624 ± 0.014	0.432TyrTrp: 0.432 ± 0.007	0.946TyrTyr: 0.946 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.002

Statistics based on 33018 proteins (11777400 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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