Amino acid dipepetide frequency for Beihai barnacle virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.741AlaAla: 12.741 ± 1.68
1.481AlaCys: 1.481 ± 0.79
4.148AlaAsp: 4.148 ± 1.223
5.037AlaGlu: 5.037 ± 0.981
4.148AlaPhe: 4.148 ± 1.755
4.148AlaGly: 4.148 ± 1.156
3.259AlaHis: 3.259 ± 0.511
4.444AlaIle: 4.444 ± 2.491
3.852AlaLys: 3.852 ± 1.368
7.407AlaLeu: 7.407 ± 1.238
3.259AlaMet: 3.259 ± 1.186
3.556AlaAsn: 3.556 ± 0.695
6.519AlaPro: 6.519 ± 1.135
2.667AlaGln: 2.667 ± 1.596
5.926AlaArg: 5.926 ± 1.864
7.111AlaSer: 7.111 ± 2.747
8.0AlaThr: 8.0 ± 1.759
7.407AlaVal: 7.407 ± 2.035
1.185AlaTrp: 1.185 ± 0.973
2.667AlaTyr: 2.667 ± 1.011
0.0AlaXaa: 0.0 ± 0.0
Cys
1.481CysAla: 1.481 ± 0.724
0.296CysCys: 0.296 ± 0.158
2.667CysAsp: 2.667 ± 0.352
1.185CysGlu: 1.185 ± 0.632
1.778CysPhe: 1.778 ± 0.608
0.0CysGly: 0.0 ± 0.0
0.296CysHis: 0.296 ± 0.158
0.296CysIle: 0.296 ± 0.158
1.778CysLys: 1.778 ± 0.712
0.593CysLeu: 0.593 ± 0.421
0.593CysMet: 0.593 ± 0.316
0.889CysAsn: 0.889 ± 0.474
0.296CysPro: 0.296 ± 0.158
0.889CysGln: 0.889 ± 0.446
0.296CysArg: 0.296 ± 0.5
0.889CysSer: 0.889 ± 0.393
1.185CysThr: 1.185 ± 0.548
1.481CysVal: 1.481 ± 0.834
0.0CysTrp: 0.0 ± 0.0
0.296CysTyr: 0.296 ± 0.158
0.0CysXaa: 0.0 ± 0.0
Asp
4.741AspAla: 4.741 ± 1.865
1.185AspCys: 1.185 ± 0.709
3.556AspAsp: 3.556 ± 0.939
4.148AspGlu: 4.148 ± 1.143
3.259AspPhe: 3.259 ± 1.245
4.741AspGly: 4.741 ± 0.818
1.481AspHis: 1.481 ± 0.99
2.667AspIle: 2.667 ± 1.011
2.074AspLys: 2.074 ± 0.75
5.926AspLeu: 5.926 ± 2.108
2.074AspMet: 2.074 ± 0.795
1.778AspAsn: 1.778 ± 0.948
2.074AspPro: 2.074 ± 0.577
2.963AspGln: 2.963 ± 1.134
3.259AspArg: 3.259 ± 1.105
4.444AspSer: 4.444 ± 3.292
2.074AspThr: 2.074 ± 0.684
5.037AspVal: 5.037 ± 0.459
0.593AspTrp: 0.593 ± 0.541
1.481AspTyr: 1.481 ± 0.508
0.0AspXaa: 0.0 ± 0.0
Glu
5.037GluAla: 5.037 ± 1.672
1.481GluCys: 1.481 ± 0.508
3.556GluAsp: 3.556 ± 1.112
5.926GluGlu: 5.926 ± 2.749
1.481GluPhe: 1.481 ± 0.79
4.148GluGly: 4.148 ± 1.246
1.778GluHis: 1.778 ± 0.571
4.444GluIle: 4.444 ± 2.938
4.444GluLys: 4.444 ± 1.115
6.815GluLeu: 6.815 ± 1.887
2.074GluMet: 2.074 ± 1.107
3.556GluAsn: 3.556 ± 1.242
2.667GluPro: 2.667 ± 0.738
2.37GluGln: 2.37 ± 1.265
2.963GluArg: 2.963 ± 0.691
3.556GluSer: 3.556 ± 1.082
0.593GluThr: 0.593 ± 0.316
6.519GluVal: 6.519 ± 1.799
1.481GluTrp: 1.481 ± 0.724
2.963GluTyr: 2.963 ± 0.698
0.0GluXaa: 0.0 ± 0.0
Phe
2.074PheAla: 2.074 ± 1.103
0.296PheCys: 0.296 ± 0.158
2.667PheAsp: 2.667 ± 0.738
2.074PheGlu: 2.074 ± 0.74
0.296PhePhe: 0.296 ± 0.158
3.852PheGly: 3.852 ± 2.166
0.593PheHis: 0.593 ± 0.316
0.889PheIle: 0.889 ± 0.474
1.185PheLys: 1.185 ± 0.492
3.556PheLeu: 3.556 ± 0.481
1.481PheMet: 1.481 ± 0.79
0.889PheAsn: 0.889 ± 0.393
1.778PhePro: 1.778 ± 0.892
2.37PheGln: 2.37 ± 0.446
1.778PheArg: 1.778 ± 0.771
1.778PheSer: 1.778 ± 0.948
2.074PheThr: 2.074 ± 1.107
2.667PheVal: 2.667 ± 0.882
0.593PheTrp: 0.593 ± 0.541
0.593PheTyr: 0.593 ± 0.421
0.0PheXaa: 0.0 ± 0.0
Gly
6.519GlyAla: 6.519 ± 4.744
1.778GlyCys: 1.778 ± 0.621
4.148GlyAsp: 4.148 ± 0.824
5.63GlyGlu: 5.63 ± 1.548
0.296GlyPhe: 0.296 ± 0.5
5.63GlyGly: 5.63 ± 1.01
1.778GlyHis: 1.778 ± 0.786
4.444GlyIle: 4.444 ± 3.143
5.037GlyLys: 5.037 ± 0.575
3.259GlyLeu: 3.259 ± 1.954
2.667GlyMet: 2.667 ± 1.844
2.667GlyAsn: 2.667 ± 0.951
2.667GlyPro: 2.667 ± 1.107
1.481GlyGln: 1.481 ± 0.79
4.741GlyArg: 4.741 ± 0.868
2.963GlySer: 2.963 ± 0.584
4.148GlyThr: 4.148 ± 0.989
5.63GlyVal: 5.63 ± 0.8
1.185GlyTrp: 1.185 ± 0.632
4.444GlyTyr: 4.444 ± 0.991
0.0GlyXaa: 0.0 ± 0.0
His
2.37HisAla: 2.37 ± 0.871
0.593HisCys: 0.593 ± 0.316
2.074HisAsp: 2.074 ± 1.403
2.667HisGlu: 2.667 ± 0.352
0.889HisPhe: 0.889 ± 0.393
1.481HisGly: 1.481 ± 0.523
1.185HisHis: 1.185 ± 0.492
0.296HisIle: 0.296 ± 0.603
0.296HisLys: 0.296 ± 0.158
2.074HisLeu: 2.074 ± 1.215
0.593HisMet: 0.593 ± 0.316
1.185HisAsn: 1.185 ± 0.709
1.481HisPro: 1.481 ± 0.615
0.593HisGln: 0.593 ± 0.421
1.185HisArg: 1.185 ± 0.426
2.963HisSer: 2.963 ± 0.821
2.37HisThr: 2.37 ± 0.62
2.963HisVal: 2.963 ± 0.852
0.889HisTrp: 0.889 ± 0.474
0.296HisTyr: 0.296 ± 0.158
0.0HisXaa: 0.0 ± 0.0
Ile
4.741IleAla: 4.741 ± 3.865
1.185IleCys: 1.185 ± 0.459
3.852IleAsp: 3.852 ± 0.698
4.741IleGlu: 4.741 ± 1.539
0.889IlePhe: 0.889 ± 0.474
4.148IleGly: 4.148 ± 0.873
1.778IleHis: 1.778 ± 0.348
2.074IleIle: 2.074 ± 0.488
3.259IleLys: 3.259 ± 1.553
2.667IleLeu: 2.667 ± 1.337
1.778IleMet: 1.778 ± 0.662
1.778IleAsn: 1.778 ± 0.884
2.37IlePro: 2.37 ± 0.908
1.185IleGln: 1.185 ± 0.885
2.667IleArg: 2.667 ± 0.697
1.778IleSer: 1.778 ± 0.348
3.259IleThr: 3.259 ± 1.002
3.556IleVal: 3.556 ± 0.991
0.889IleTrp: 0.889 ± 0.474
1.185IleTyr: 1.185 ± 0.632
0.0IleXaa: 0.0 ± 0.0
Lys
3.852LysAla: 3.852 ± 0.709
0.889LysCys: 0.889 ± 0.521
2.667LysAsp: 2.667 ± 1.006
5.333LysGlu: 5.333 ± 1.953
2.074LysPhe: 2.074 ± 0.75
2.667LysGly: 2.667 ± 0.723
0.593LysHis: 0.593 ± 0.316
3.259LysIle: 3.259 ± 1.337
0.889LysLys: 0.889 ± 0.474
4.741LysLeu: 4.741 ± 2.222
1.481LysMet: 1.481 ± 0.508
2.667LysAsn: 2.667 ± 1.423
3.259LysPro: 3.259 ± 0.832
1.185LysGln: 1.185 ± 0.426
2.667LysArg: 2.667 ± 1.423
2.074LysSer: 2.074 ± 1.107
1.185LysThr: 1.185 ± 0.426
2.37LysVal: 2.37 ± 0.889
0.296LysTrp: 0.296 ± 0.158
0.889LysTyr: 0.889 ± 0.393
0.0LysXaa: 0.0 ± 0.0
Leu
7.407LeuAla: 7.407 ± 1.584
1.778LeuCys: 1.778 ± 0.571
4.741LeuAsp: 4.741 ± 2.382
2.37LeuGlu: 2.37 ± 1.102
1.481LeuPhe: 1.481 ± 0.615
6.222LeuGly: 6.222 ± 1.228
1.778LeuHis: 1.778 ± 1.039
1.778LeuIle: 1.778 ± 1.178
1.778LeuLys: 1.778 ± 0.348
4.444LeuLeu: 4.444 ± 1.999
2.667LeuMet: 2.667 ± 0.925
3.852LeuAsn: 3.852 ± 0.847
3.556LeuPro: 3.556 ± 0.573
4.444LeuGln: 4.444 ± 1.523
5.333LeuArg: 5.333 ± 1.723
4.741LeuSer: 4.741 ± 0.79
2.667LeuThr: 2.667 ± 1.887
6.519LeuVal: 6.519 ± 0.754
0.593LeuTrp: 0.593 ± 0.421
2.37LeuTyr: 2.37 ± 1.102
0.0LeuXaa: 0.0 ± 0.0
Met
2.37MetAla: 2.37 ± 0.919
0.296MetCys: 0.296 ± 0.158
0.889MetAsp: 0.889 ± 0.615
1.185MetGlu: 1.185 ± 0.426
0.889MetPhe: 0.889 ± 0.73
2.37MetGly: 2.37 ± 0.889
0.593MetHis: 0.593 ± 0.316
1.778MetIle: 1.778 ± 0.621
1.185MetLys: 1.185 ± 0.426
2.074MetLeu: 2.074 ± 0.488
1.185MetMet: 1.185 ± 0.426
0.593MetAsn: 0.593 ± 0.316
1.778MetPro: 1.778 ± 0.892
2.074MetGln: 2.074 ± 1.107
2.963MetArg: 2.963 ± 0.852
3.556MetSer: 3.556 ± 1.278
2.37MetThr: 2.37 ± 0.731
2.37MetVal: 2.37 ± 0.871
0.296MetTrp: 0.296 ± 0.158
0.889MetTyr: 0.889 ± 0.615
0.0MetXaa: 0.0 ± 0.0
Asn
4.741AsnAla: 4.741 ± 0.892
0.889AsnCys: 0.889 ± 0.714
1.185AsnAsp: 1.185 ± 0.426
3.852AsnGlu: 3.852 ± 1.044
0.889AsnPhe: 0.889 ± 0.446
2.963AsnGly: 2.963 ± 0.83
1.481AsnHis: 1.481 ± 0.508
4.148AsnIle: 4.148 ± 1.755
1.481AsnLys: 1.481 ± 0.79
2.667AsnLeu: 2.667 ± 0.352
0.593AsnMet: 0.593 ± 0.316
0.593AsnAsn: 0.593 ± 0.421
1.185AsnPro: 1.185 ± 0.459
1.185AsnGln: 1.185 ± 1.717
1.481AsnArg: 1.481 ± 0.79
2.074AsnSer: 2.074 ± 0.74
1.481AsnThr: 1.481 ± 1.328
2.667AsnVal: 2.667 ± 1.124
0.593AsnTrp: 0.593 ± 0.316
1.185AsnTyr: 1.185 ± 0.632
0.0AsnXaa: 0.0 ± 0.0
Pro
7.704ProAla: 7.704 ± 2.785
0.593ProCys: 0.593 ± 1.107
3.556ProAsp: 3.556 ± 0.481
3.852ProGlu: 3.852 ± 2.055
0.889ProPhe: 0.889 ± 1.135
5.037ProGly: 5.037 ± 1.442
2.074ProHis: 2.074 ± 0.828
1.778ProIle: 1.778 ± 0.348
1.778ProLys: 1.778 ± 0.348
2.37ProLeu: 2.37 ± 1.432
0.889ProMet: 0.889 ± 0.446
2.074ProAsn: 2.074 ± 1.057
2.37ProPro: 2.37 ± 1.558
0.889ProGln: 0.889 ± 0.446
2.667ProArg: 2.667 ± 0.697
1.778ProSer: 1.778 ± 0.621
2.963ProThr: 2.963 ± 0.584
2.37ProVal: 2.37 ± 1.724
0.593ProTrp: 0.593 ± 0.782
1.481ProTyr: 1.481 ± 0.523
0.0ProXaa: 0.0 ± 0.0
Gln
2.667GlnAla: 2.667 ± 1.065
0.593GlnCys: 0.593 ± 0.316
2.37GlnAsp: 2.37 ± 0.811
2.074GlnGlu: 2.074 ± 1.107
1.778GlnPhe: 1.778 ± 0.948
3.259GlnGly: 3.259 ± 0.624
0.593GlnHis: 0.593 ± 0.316
2.963GlnIle: 2.963 ± 1.002
1.185GlnLys: 1.185 ± 0.426
2.37GlnLeu: 2.37 ± 0.643
1.481GlnMet: 1.481 ± 0.79
2.37GlnAsn: 2.37 ± 0.638
1.778GlnPro: 1.778 ± 0.865
1.778GlnGln: 1.778 ± 0.571
2.37GlnArg: 2.37 ± 0.889
1.481GlnSer: 1.481 ± 1.004
2.37GlnThr: 2.37 ± 0.908
1.778GlnVal: 1.778 ± 0.786
0.296GlnTrp: 0.296 ± 0.158
0.593GlnTyr: 0.593 ± 0.487
0.0GlnXaa: 0.0 ± 0.0
Arg
5.926ArgAla: 5.926 ± 1.148
0.296ArgCys: 0.296 ± 0.603
4.148ArgAsp: 4.148 ± 0.706
4.444ArgGlu: 4.444 ± 1.782
1.778ArgPhe: 1.778 ± 0.884
6.222ArgGly: 6.222 ± 1.739
2.963ArgHis: 2.963 ± 1.155
3.259ArgIle: 3.259 ± 1.245
2.37ArgLys: 2.37 ± 0.956
4.148ArgLeu: 4.148 ± 1.278
1.185ArgMet: 1.185 ± 0.459
1.778ArgAsn: 1.778 ± 0.608
1.778ArgPro: 1.778 ± 0.571
2.37ArgGln: 2.37 ± 1.265
4.444ArgArg: 4.444 ± 1.804
4.148ArgSer: 4.148 ± 1.466
2.963ArgThr: 2.963 ± 1.333
5.037ArgVal: 5.037 ± 2.047
2.074ArgTrp: 2.074 ± 0.577
1.778ArgTyr: 1.778 ± 0.621
0.0ArgXaa: 0.0 ± 0.0
Ser
8.0SerAla: 8.0 ± 1.597
1.185SerCys: 1.185 ± 0.426
2.667SerAsp: 2.667 ± 0.56
3.852SerGlu: 3.852 ± 1.368
3.259SerPhe: 3.259 ± 1.1
5.63SerGly: 5.63 ± 2.931
1.481SerHis: 1.481 ± 0.743
2.963SerIle: 2.963 ± 2.305
2.667SerLys: 2.667 ± 0.593
2.963SerLeu: 2.963 ± 0.568
1.481SerMet: 1.481 ± 0.484
1.778SerAsn: 1.778 ± 0.892
3.259SerPro: 3.259 ± 1.007
1.481SerGln: 1.481 ± 0.92
4.148SerArg: 4.148 ± 0.824
5.037SerSer: 5.037 ± 2.936
3.556SerThr: 3.556 ± 0.991
5.037SerVal: 5.037 ± 0.575
0.296SerTrp: 0.296 ± 0.158
2.37SerTyr: 2.37 ± 0.811
0.0SerXaa: 0.0 ± 0.0
Thr
5.333ThrAla: 5.333 ± 1.019
1.481ThrCys: 1.481 ± 0.508
2.37ThrAsp: 2.37 ± 1.102
3.259ThrGlu: 3.259 ± 1.346
2.37ThrPhe: 2.37 ± 0.62
1.778ThrGly: 1.778 ± 1.352
0.889ThrHis: 0.889 ± 0.474
2.963ThrIle: 2.963 ± 0.691
3.259ThrLys: 3.259 ± 1.739
3.852ThrLeu: 3.852 ± 1.267
2.074ThrMet: 2.074 ± 0.909
0.296ThrAsn: 0.296 ± 0.158
3.852ThrPro: 3.852 ± 1.062
1.778ThrGln: 1.778 ± 0.571
3.556ThrArg: 3.556 ± 1.784
3.259ThrSer: 3.259 ± 1.144
4.148ThrThr: 4.148 ± 1.929
4.741ThrVal: 4.741 ± 1.865
1.481ThrTrp: 1.481 ± 0.396
2.074ThrTyr: 2.074 ± 1.034
0.0ThrXaa: 0.0 ± 0.0
Val
7.704ValAla: 7.704 ± 2.093
0.0ValCys: 0.0 ± 0.0
4.741ValAsp: 4.741 ± 3.171
2.963ValGlu: 2.963 ± 1.007
2.667ValPhe: 2.667 ± 0.882
4.444ValGly: 4.444 ± 1.596
2.074ValHis: 2.074 ± 0.75
2.963ValIle: 2.963 ± 1.308
3.556ValLys: 3.556 ± 1.439
5.333ValLeu: 5.333 ± 0.808
2.074ValMet: 2.074 ± 0.892
3.556ValAsn: 3.556 ± 1.158
2.667ValPro: 2.667 ± 0.829
3.556ValGln: 3.556 ± 1.242
5.63ValArg: 5.63 ± 0.779
6.815ValSer: 6.815 ± 1.95
6.222ValThr: 6.222 ± 1.343
7.111ValVal: 7.111 ± 1.914
0.593ValTrp: 0.593 ± 0.421
3.556ValTyr: 3.556 ± 1.276
0.0ValXaa: 0.0 ± 0.0
Trp
0.593TrpAla: 0.593 ± 0.541
0.593TrpCys: 0.593 ± 0.487
1.185TrpAsp: 1.185 ± 0.632
1.481TrpGlu: 1.481 ± 0.615
0.593TrpPhe: 0.593 ± 0.316
0.889TrpGly: 0.889 ± 0.393
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.889TrpLys: 0.889 ± 0.474
0.889TrpLeu: 0.889 ± 0.521
0.889TrpMet: 0.889 ± 0.474
0.593TrpAsn: 0.593 ± 0.316
0.593TrpPro: 0.593 ± 1.721
0.296TrpGln: 0.296 ± 0.158
2.074TrpArg: 2.074 ± 0.795
1.185TrpSer: 1.185 ± 0.842
0.296TrpThr: 0.296 ± 0.158
0.593TrpVal: 0.593 ± 0.316
0.296TrpTrp: 0.296 ± 0.603
0.296TrpTyr: 0.296 ± 0.158
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.963TyrAla: 2.963 ± 0.691
0.296TyrCys: 0.296 ± 0.158
2.37TyrAsp: 2.37 ± 0.395
1.778TyrGlu: 1.778 ± 0.713
1.778TyrPhe: 1.778 ± 0.621
1.481TyrGly: 1.481 ± 0.396
1.778TyrHis: 1.778 ± 0.786
2.37TyrIle: 2.37 ± 0.889
2.074TyrLys: 2.074 ± 1.107
2.37TyrLeu: 2.37 ± 0.871
0.889TyrMet: 0.889 ± 0.446
0.889TyrAsn: 0.889 ± 0.474
1.778TyrPro: 1.778 ± 2.208
0.593TyrGln: 0.593 ± 0.421
2.963TyrArg: 2.963 ± 1.013
1.481TyrSer: 1.481 ± 0.523
1.185TyrThr: 1.185 ± 0.492
2.37TyrVal: 2.37 ± 0.908
0.0TyrTrp: 0.0 ± 0.0
0.296TyrTyr: 0.296 ± 0.158
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3376 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski