Amino acid dipepetide frequency for Human T-cell leukemia virus 2 (HTLV-2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.318AlaAla: 6.318 ± 1.43
0.862AlaCys: 0.862 ± 0.55
1.149AlaAsp: 1.149 ± 0.687
1.149AlaGlu: 1.149 ± 0.361
4.021AlaPhe: 4.021 ± 1.111
2.298AlaGly: 2.298 ± 0.357
2.298AlaHis: 2.298 ± 0.592
4.308AlaIle: 4.308 ± 0.662
1.436AlaLys: 1.436 ± 0.45
10.052AlaLeu: 10.052 ± 1.608
0.0AlaMet: 0.0 ± 0.0
1.723AlaAsn: 1.723 ± 0.707
5.169AlaPro: 5.169 ± 0.916
2.01AlaGln: 2.01 ± 0.751
1.436AlaArg: 1.436 ± 0.386
3.733AlaSer: 3.733 ± 0.785
2.01AlaThr: 2.01 ± 0.429
2.298AlaVal: 2.298 ± 0.503
2.298AlaTrp: 2.298 ± 0.294
2.585AlaTyr: 2.585 ± 0.495
0.0AlaXaa: 0.0 ± 0.0
Cys
0.862CysAla: 0.862 ± 0.353
0.287CysCys: 0.287 ± 0.316
0.287CysAsp: 0.287 ± 0.183
0.574CysGlu: 0.574 ± 0.312
2.01CysPhe: 2.01 ± 0.615
1.436CysGly: 1.436 ± 0.274
0.574CysHis: 0.574 ± 0.333
0.862CysIle: 0.862 ± 0.415
0.574CysLys: 0.574 ± 0.298
2.01CysLeu: 2.01 ± 0.741
0.287CysMet: 0.287 ± 0.316
0.862CysAsn: 0.862 ± 0.381
4.595CysPro: 4.595 ± 0.49
4.021CysGln: 4.021 ± 1.028
0.287CysArg: 0.287 ± 0.183
1.723CysSer: 1.723 ± 0.596
2.298CysThr: 2.298 ± 0.357
0.574CysVal: 0.574 ± 0.496
0.0CysTrp: 0.0 ± 0.0
0.287CysTyr: 0.287 ± 0.316
0.0CysXaa: 0.0 ± 0.0
Asp
2.01AspAla: 2.01 ± 0.566
2.298AspCys: 2.298 ± 0.592
1.436AspAsp: 1.436 ± 0.628
0.287AspGlu: 0.287 ± 0.375
2.01AspPhe: 2.01 ± 0.69
1.149AspGly: 1.149 ± 0.666
0.287AspHis: 0.287 ± 0.183
1.436AspIle: 1.436 ± 0.413
1.436AspLys: 1.436 ± 0.274
7.467AspLeu: 7.467 ± 0.844
0.574AspMet: 0.574 ± 0.568
2.01AspAsn: 2.01 ± 0.147
4.595AspPro: 4.595 ± 0.702
2.01AspGln: 2.01 ± 0.42
0.574AspArg: 0.574 ± 0.45
0.862AspSer: 0.862 ± 0.381
2.585AspThr: 2.585 ± 0.877
0.574AspVal: 0.574 ± 0.298
0.287AspTrp: 0.287 ± 0.375
0.862AspTyr: 0.862 ± 0.353
0.0AspXaa: 0.0 ± 0.0
Glu
3.446GluAla: 3.446 ± 0.449
0.862GluCys: 0.862 ± 0.353
0.287GluAsp: 0.287 ± 0.375
3.446GluGlu: 3.446 ± 0.948
0.574GluPhe: 0.574 ± 0.367
1.723GluGly: 1.723 ± 0.707
1.436GluHis: 1.436 ± 0.314
1.436GluIle: 1.436 ± 0.6
2.01GluLys: 2.01 ± 0.394
1.436GluLeu: 1.436 ± 0.652
1.149GluMet: 1.149 ± 0.392
0.0GluAsn: 0.0 ± 0.0
5.169GluPro: 5.169 ± 0.971
0.862GluGln: 0.862 ± 0.586
1.723GluArg: 1.723 ± 0.321
0.574GluSer: 0.574 ± 0.312
2.298GluThr: 2.298 ± 0.231
1.436GluVal: 1.436 ± 0.551
0.0GluTrp: 0.0 ± 0.0
1.436GluTyr: 1.436 ± 0.325
0.0GluXaa: 0.0 ± 0.0
Phe
0.287PheAla: 0.287 ± 0.183
0.574PheCys: 0.574 ± 0.333
2.01PheAsp: 2.01 ± 0.661
0.862PheGlu: 0.862 ± 0.685
0.862PhePhe: 0.862 ± 0.415
1.149PheGly: 1.149 ± 0.732
2.01PheHis: 2.01 ± 0.961
0.862PheIle: 0.862 ± 0.586
0.862PheLys: 0.862 ± 0.355
5.169PheLeu: 5.169 ± 0.481
0.862PheMet: 0.862 ± 0.353
1.149PheAsn: 1.149 ± 0.851
4.021PhePro: 4.021 ± 1.128
2.298PheGln: 2.298 ± 0.567
1.436PheArg: 1.436 ± 0.537
2.298PheSer: 2.298 ± 0.709
0.862PheThr: 0.862 ± 0.381
0.862PheVal: 0.862 ± 0.353
0.287PheTrp: 0.287 ± 0.316
0.287PheTyr: 0.287 ± 0.183
0.0PheXaa: 0.0 ± 0.0
Gly
3.446GlyAla: 3.446 ± 0.883
0.574GlyCys: 0.574 ± 0.496
1.723GlyAsp: 1.723 ± 0.975
2.872GlyGlu: 2.872 ± 0.868
0.862GlyPhe: 0.862 ± 0.415
1.436GlyGly: 1.436 ± 0.616
2.298GlyHis: 2.298 ± 0.721
1.436GlyIle: 1.436 ± 0.938
2.298GlyLys: 2.298 ± 0.579
10.339GlyLeu: 10.339 ± 0.602
1.149GlyMet: 1.149 ± 0.367
1.436GlyAsn: 1.436 ± 0.274
5.169GlyPro: 5.169 ± 0.525
3.446GlyGln: 3.446 ± 0.753
2.298GlyArg: 2.298 ± 0.478
2.585GlySer: 2.585 ± 0.339
3.733GlyThr: 3.733 ± 0.365
1.436GlyVal: 1.436 ± 0.33
0.287GlyTrp: 0.287 ± 0.316
3.159GlyTyr: 3.159 ± 0.352
0.0GlyXaa: 0.0 ± 0.0
His
1.149HisAla: 1.149 ± 0.503
0.574HisCys: 0.574 ± 0.298
1.149HisAsp: 1.149 ± 0.313
0.287HisGlu: 0.287 ± 0.183
0.862HisPhe: 0.862 ± 0.743
2.01HisGly: 2.01 ± 0.741
3.446HisHis: 3.446 ± 1.17
2.01HisIle: 2.01 ± 0.999
0.574HisLys: 0.574 ± 0.298
2.585HisLeu: 2.585 ± 0.579
0.574HisMet: 0.574 ± 0.367
2.01HisAsn: 2.01 ± 0.429
2.872HisPro: 2.872 ± 0.411
2.872HisGln: 2.872 ± 0.411
1.149HisArg: 1.149 ± 0.405
2.01HisSer: 2.01 ± 0.693
2.298HisThr: 2.298 ± 0.567
2.585HisVal: 2.585 ± 0.658
2.872HisTrp: 2.872 ± 0.945
0.574HisTyr: 0.574 ± 0.367
0.0HisXaa: 0.0 ± 0.0
Ile
1.149IleAla: 1.149 ± 0.556
1.149IleCys: 1.149 ± 0.361
2.01IleAsp: 2.01 ± 0.417
0.287IleGlu: 0.287 ± 0.183
2.01IlePhe: 2.01 ± 0.666
2.01IleGly: 2.01 ± 0.46
2.01IleHis: 2.01 ± 0.741
1.723IleIle: 1.723 ± 0.442
2.298IleLys: 2.298 ± 0.6
11.2IleLeu: 11.2 ± 1.347
0.287IleMet: 0.287 ± 0.313
1.723IleAsn: 1.723 ± 0.321
5.744IlePro: 5.744 ± 0.838
2.01IleGln: 2.01 ± 1.054
0.574IleArg: 0.574 ± 0.367
5.457IleSer: 5.457 ± 1.064
3.446IleThr: 3.446 ± 1.265
1.149IleVal: 1.149 ± 0.581
1.436IleTrp: 1.436 ± 0.325
0.574IleTyr: 0.574 ± 0.333
0.0IleXaa: 0.0 ± 0.0
Lys
2.872LysAla: 2.872 ± 0.475
0.287LysCys: 0.287 ± 0.316
2.872LysAsp: 2.872 ± 0.945
2.298LysGlu: 2.298 ± 0.592
0.862LysPhe: 0.862 ± 0.743
2.298LysGly: 2.298 ± 0.745
0.862LysHis: 0.862 ± 0.385
1.149LysIle: 1.149 ± 0.338
1.723LysLys: 1.723 ± 0.847
2.298LysLeu: 2.298 ± 0.802
0.574LysMet: 0.574 ± 0.333
2.585LysAsn: 2.585 ± 0.557
2.585LysPro: 2.585 ± 0.513
1.723LysGln: 1.723 ± 0.585
1.436LysArg: 1.436 ± 0.4
0.862LysSer: 0.862 ± 0.381
4.021LysThr: 4.021 ± 0.508
2.585LysVal: 2.585 ± 1.075
1.149LysTrp: 1.149 ± 0.493
2.01LysTyr: 2.01 ± 1.283
0.0LysXaa: 0.0 ± 0.0
Leu
9.765LeuAla: 9.765 ± 0.8
3.159LeuCys: 3.159 ± 0.362
5.169LeuAsp: 5.169 ± 0.864
3.159LeuGlu: 3.159 ± 0.774
2.585LeuPhe: 2.585 ± 1.598
6.031LeuGly: 6.031 ± 0.508
7.18LeuHis: 7.18 ± 1.142
6.893LeuIle: 6.893 ± 1.122
4.308LeuLys: 4.308 ± 0.862
15.796LeuLeu: 15.796 ± 1.288
0.287LeuMet: 0.287 ± 0.286
6.893LeuAsn: 6.893 ± 1.335
12.924LeuPro: 12.924 ± 1.776
13.498LeuGln: 13.498 ± 2.243
8.616LeuArg: 8.616 ± 1.735
6.605LeuSer: 6.605 ± 1.002
6.605LeuThr: 6.605 ± 1.936
6.031LeuVal: 6.031 ± 0.686
1.723LeuTrp: 1.723 ± 0.321
2.585LeuTyr: 2.585 ± 1.408
0.0LeuXaa: 0.0 ± 0.0
Met
1.149MetAla: 1.149 ± 0.405
0.0MetCys: 0.0 ± 0.0
1.149MetAsp: 1.149 ± 0.897
0.0MetGlu: 0.0 ± 0.0
0.862MetPhe: 0.862 ± 0.685
2.01MetGly: 2.01 ± 0.415
0.0MetHis: 0.0 ± 0.0
0.287MetIle: 0.287 ± 0.375
0.862MetLys: 0.862 ± 0.353
1.149MetLeu: 1.149 ± 0.338
0.0MetMet: 0.0 ± 0.0
0.287MetAsn: 0.287 ± 0.183
0.862MetPro: 0.862 ± 0.595
1.723MetGln: 1.723 ± 0.707
0.574MetArg: 0.574 ± 0.333
0.287MetSer: 0.287 ± 0.183
1.436MetThr: 1.436 ± 0.4
0.287MetVal: 0.287 ± 0.316
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.436AsnAla: 1.436 ± 0.45
0.574AsnCys: 0.574 ± 0.298
0.862AsnAsp: 0.862 ± 0.415
0.574AsnGlu: 0.574 ± 0.367
1.149AsnPhe: 1.149 ± 0.338
2.298AsnGly: 2.298 ± 0.567
0.862AsnHis: 0.862 ± 0.381
2.585AsnIle: 2.585 ± 0.913
2.01AsnLys: 2.01 ± 0.451
4.308AsnLeu: 4.308 ± 0.411
0.287AsnMet: 0.287 ± 0.183
1.436AsnAsn: 1.436 ± 0.274
4.308AsnPro: 4.308 ± 1.041
2.585AsnGln: 2.585 ± 0.514
1.149AsnArg: 1.149 ± 1.006
2.872AsnSer: 2.872 ± 0.522
3.733AsnThr: 3.733 ± 0.807
1.436AsnVal: 1.436 ± 0.274
0.574AsnTrp: 0.574 ± 0.298
0.574AsnTyr: 0.574 ± 0.298
0.0AsnXaa: 0.0 ± 0.0
Pro
3.446ProAla: 3.446 ± 0.357
3.733ProCys: 3.733 ± 0.845
2.01ProAsp: 2.01 ± 0.839
3.446ProGlu: 3.446 ± 0.778
1.149ProPhe: 1.149 ± 0.556
7.18ProGly: 7.18 ± 0.993
2.585ProHis: 2.585 ± 0.543
9.19ProIle: 9.19 ± 1.839
5.744ProLys: 5.744 ± 1.136
11.488ProLeu: 11.488 ± 1.005
2.01ProMet: 2.01 ± 0.724
2.872ProAsn: 2.872 ± 0.847
22.401ProPro: 22.401 ± 3.328
6.893ProGln: 6.893 ± 0.998
6.605ProArg: 6.605 ± 0.876
13.785ProSer: 13.785 ± 2.827
10.626ProThr: 10.626 ± 0.937
5.457ProVal: 5.457 ± 1.489
2.585ProTrp: 2.585 ± 0.513
3.733ProTyr: 3.733 ± 0.694
0.0ProXaa: 0.0 ± 0.0
Gln
8.041GlnAla: 8.041 ± 1.131
2.298GlnCys: 2.298 ± 0.533
2.872GlnAsp: 2.872 ± 0.784
4.021GlnGlu: 4.021 ± 0.789
2.872GlnPhe: 2.872 ± 1.075
4.308GlnGly: 4.308 ± 0.588
1.149GlnHis: 1.149 ± 0.733
2.01GlnIle: 2.01 ± 0.445
1.436GlnLys: 1.436 ± 0.45
6.605GlnLeu: 6.605 ± 1.178
0.862GlnMet: 0.862 ± 0.353
2.298GlnAsn: 2.298 ± 0.747
7.754GlnPro: 7.754 ± 0.656
8.041GlnGln: 8.041 ± 1.964
1.723GlnArg: 1.723 ± 0.721
2.585GlnSer: 2.585 ± 1.21
5.744GlnThr: 5.744 ± 1.2
2.585GlnVal: 2.585 ± 0.356
0.862GlnTrp: 0.862 ± 0.381
2.585GlnTyr: 2.585 ± 0.578
0.0GlnXaa: 0.0 ± 0.0
Arg
2.298ArgAla: 2.298 ± 0.825
1.149ArgCys: 1.149 ± 0.338
3.446ArgAsp: 3.446 ± 1.195
1.723ArgGlu: 1.723 ± 0.278
2.298ArgPhe: 2.298 ± 0.668
4.021ArgGly: 4.021 ± 1.114
0.574ArgHis: 0.574 ± 0.496
0.862ArgIle: 0.862 ± 0.355
0.862ArgLys: 0.862 ± 0.385
5.457ArgLeu: 5.457 ± 0.875
0.862ArgMet: 0.862 ± 0.353
0.862ArgAsn: 0.862 ± 0.52
5.457ArgPro: 5.457 ± 1.163
1.723ArgGln: 1.723 ± 0.725
5.457ArgArg: 5.457 ± 1.118
2.298ArgSer: 2.298 ± 0.34
2.298ArgThr: 2.298 ± 0.717
1.723ArgVal: 1.723 ± 0.596
0.862ArgTrp: 0.862 ± 0.55
0.287ArgTyr: 0.287 ± 0.183
0.0ArgXaa: 0.0 ± 0.0
Ser
4.882SerAla: 4.882 ± 0.782
1.436SerCys: 1.436 ± 0.413
1.723SerAsp: 1.723 ± 0.468
0.574SerGlu: 0.574 ± 0.298
1.436SerPhe: 1.436 ± 0.816
4.308SerGly: 4.308 ± 0.694
2.01SerHis: 2.01 ± 0.147
2.01SerIle: 2.01 ± 0.751
1.723SerLys: 1.723 ± 0.761
12.636SerLeu: 12.636 ± 2.339
0.862SerMet: 0.862 ± 0.667
1.436SerAsn: 1.436 ± 0.386
13.498SerPro: 13.498 ± 1.537
3.159SerGln: 3.159 ± 1.155
2.298SerArg: 2.298 ± 0.761
6.893SerSer: 6.893 ± 2.085
6.318SerThr: 6.318 ± 0.933
2.01SerVal: 2.01 ± 0.505
2.01SerTrp: 2.01 ± 0.86
1.436SerTyr: 1.436 ± 0.778
0.0SerXaa: 0.0 ± 0.0
Thr
1.723ThrAla: 1.723 ± 0.339
2.01ThrCys: 2.01 ± 0.417
1.723ThrAsp: 1.723 ± 0.761
2.298ThrGlu: 2.298 ± 0.636
0.862ThrPhe: 0.862 ± 0.385
3.446ThrGly: 3.446 ± 1.44
3.733ThrHis: 3.733 ± 0.847
4.595ThrIle: 4.595 ± 1.585
1.723ThrLys: 1.723 ± 0.697
8.903ThrLeu: 8.903 ± 1.303
0.574ThrMet: 0.574 ± 0.496
3.733ThrAsn: 3.733 ± 0.553
12.636ThrPro: 12.636 ± 1.661
5.457ThrGln: 5.457 ± 1.0
3.446ThrArg: 3.446 ± 0.562
5.744ThrSer: 5.744 ± 1.476
7.467ThrThr: 7.467 ± 1.041
1.436ThrVal: 1.436 ± 0.628
1.149ThrTrp: 1.149 ± 1.176
0.862ThrTyr: 0.862 ± 0.586
0.0ThrXaa: 0.0 ± 0.0
Val
1.149ValAla: 1.149 ± 0.338
0.862ValCys: 0.862 ± 0.743
1.723ValAsp: 1.723 ± 0.801
2.872ValGlu: 2.872 ± 1.035
0.862ValPhe: 0.862 ± 0.415
1.149ValGly: 1.149 ± 0.361
0.287ValHis: 0.287 ± 0.316
3.446ValIle: 3.446 ± 0.656
2.01ValLys: 2.01 ± 0.415
3.733ValLeu: 3.733 ± 0.696
0.862ValMet: 0.862 ± 0.355
0.287ValAsn: 0.287 ± 0.316
4.595ValPro: 4.595 ± 1.066
3.159ValGln: 3.159 ± 0.715
1.149ValArg: 1.149 ± 0.346
6.605ValSer: 6.605 ± 1.074
0.574ValThr: 0.574 ± 0.298
4.021ValVal: 4.021 ± 1.176
0.574ValTrp: 0.574 ± 0.298
0.862ValTyr: 0.862 ± 0.848
0.0ValXaa: 0.0 ± 0.0
Trp
1.149TrpAla: 1.149 ± 0.338
0.574TrpCys: 0.574 ± 0.749
0.862TrpAsp: 0.862 ± 0.415
0.287TrpGlu: 0.287 ± 0.316
0.574TrpPhe: 0.574 ± 0.298
0.862TrpGly: 0.862 ± 0.415
0.287TrpHis: 0.287 ± 0.316
0.574TrpIle: 0.574 ± 0.298
1.723TrpLys: 1.723 ± 0.321
3.159TrpLeu: 3.159 ± 0.892
0.0TrpMet: 0.0 ± 0.0
0.574TrpAsn: 0.574 ± 0.45
1.436TrpPro: 1.436 ± 0.771
1.436TrpGln: 1.436 ± 0.45
0.574TrpArg: 0.574 ± 0.367
0.862TrpSer: 0.862 ± 0.353
3.446TrpThr: 3.446 ± 0.507
0.574TrpVal: 0.574 ± 0.367
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.574TyrAla: 0.574 ± 0.298
1.149TyrCys: 1.149 ± 0.361
0.287TyrAsp: 0.287 ± 0.316
0.287TyrGlu: 0.287 ± 0.183
0.287TyrPhe: 0.287 ± 0.183
0.862TyrGly: 0.862 ± 0.385
0.574TyrHis: 0.574 ± 0.496
0.574TyrIle: 0.574 ± 0.312
1.436TyrLys: 1.436 ± 0.652
4.021TyrLeu: 4.021 ± 0.65
0.574TyrMet: 0.574 ± 0.312
1.436TyrAsn: 1.436 ± 0.274
1.436TyrPro: 1.436 ± 0.696
1.723TyrGln: 1.723 ± 0.239
2.01TyrArg: 2.01 ± 0.417
4.021TyrSer: 4.021 ± 1.144
1.723TyrThr: 1.723 ± 0.83
1.723TyrVal: 1.723 ± 0.445
0.0TyrTrp: 0.0 ± 0.0
0.574TyrTyr: 0.574 ± 0.298
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3483 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski