Amino acid dipepetide frequency for Arracacha virus V

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.915AlaAla: 3.915 ± 1.698
1.74AlaCys: 1.74 ± 0.844
2.61AlaAsp: 2.61 ± 1.577
3.915AlaGlu: 3.915 ± 1.348
2.61AlaPhe: 2.61 ± 0.641
3.915AlaGly: 3.915 ± 1.071
2.175AlaHis: 2.175 ± 1.055
2.175AlaIle: 2.175 ± 1.886
5.655AlaLys: 5.655 ± 1.085
6.09AlaLeu: 6.09 ± 2.242
3.045AlaMet: 3.045 ± 2.488
0.87AlaAsn: 0.87 ± 0.422
1.305AlaPro: 1.305 ± 0.497
3.915AlaGln: 3.915 ± 1.538
2.61AlaArg: 2.61 ± 2.867
5.655AlaSer: 5.655 ± 0.744
0.87AlaThr: 0.87 ± 0.422
3.915AlaVal: 3.915 ± 3.051
0.435AlaTrp: 0.435 ± 0.211
2.175AlaTyr: 2.175 ± 0.772
0.0AlaXaa: 0.0 ± 0.0
Cys
1.305CysAla: 1.305 ± 0.633
0.87CysCys: 0.87 ± 0.422
0.435CysAsp: 0.435 ± 0.893
1.305CysGlu: 1.305 ± 0.633
3.045CysPhe: 3.045 ± 1.141
2.175CysGly: 2.175 ± 1.169
0.87CysHis: 0.87 ± 0.422
0.87CysIle: 0.87 ± 0.422
2.175CysLys: 2.175 ± 1.169
2.175CysLeu: 2.175 ± 3.308
0.435CysMet: 0.435 ± 0.211
0.435CysAsn: 0.435 ± 0.211
0.0CysPro: 0.0 ± 0.0
0.87CysGln: 0.87 ± 1.331
0.87CysArg: 0.87 ± 0.422
1.74CysSer: 1.74 ± 0.485
2.61CysThr: 2.61 ± 0.876
1.74CysVal: 1.74 ± 1.18
0.0CysTrp: 0.0 ± 0.0
1.74CysTyr: 1.74 ± 0.844
0.0CysXaa: 0.0 ± 0.0
Asp
2.61AspAla: 2.61 ± 1.187
0.87AspCys: 0.87 ± 0.783
2.61AspAsp: 2.61 ± 1.266
5.22AspGlu: 5.22 ± 1.383
2.61AspPhe: 2.61 ± 1.577
3.045AspGly: 3.045 ± 0.959
2.61AspHis: 2.61 ± 1.266
1.305AspIle: 1.305 ± 0.497
4.785AspLys: 4.785 ± 0.994
4.35AspLeu: 4.35 ± 0.823
0.87AspMet: 0.87 ± 0.59
3.48AspAsn: 3.48 ± 1.002
3.48AspPro: 3.48 ± 1.174
1.74AspGln: 1.74 ± 0.485
3.045AspArg: 3.045 ± 1.285
1.74AspSer: 1.74 ± 0.844
1.74AspThr: 1.74 ± 0.896
2.61AspVal: 2.61 ± 0.691
2.175AspTrp: 2.175 ± 1.169
2.175AspTyr: 2.175 ± 1.055
0.0AspXaa: 0.0 ± 0.0
Glu
3.48GluAla: 3.48 ± 1.347
2.61GluCys: 2.61 ± 1.187
6.525GluAsp: 6.525 ± 1.676
9.134GluGlu: 9.134 ± 1.17
4.785GluPhe: 4.785 ± 2.321
5.655GluGly: 5.655 ± 1.214
1.74GluHis: 1.74 ± 0.485
5.655GluIle: 5.655 ± 1.358
3.48GluLys: 3.48 ± 1.038
6.96GluLeu: 6.96 ± 1.939
0.435GluMet: 0.435 ± 0.211
1.305GluAsn: 1.305 ± 0.497
3.045GluPro: 3.045 ± 2.066
4.35GluGln: 4.35 ± 0.823
3.915GluArg: 3.915 ± 2.303
5.22GluSer: 5.22 ± 1.829
3.045GluThr: 3.045 ± 1.083
4.35GluVal: 4.35 ± 1.544
1.74GluTrp: 1.74 ± 1.189
3.045GluTyr: 3.045 ± 2.425
0.0GluXaa: 0.0 ± 0.0
Phe
2.61PheAla: 2.61 ± 1.441
1.74PheCys: 1.74 ± 0.896
2.61PheAsp: 2.61 ± 0.641
3.915PheGlu: 3.915 ± 1.899
1.305PhePhe: 1.305 ± 0.633
2.61PheGly: 2.61 ± 0.876
0.87PheHis: 0.87 ± 0.422
2.61PheIle: 2.61 ± 1.266
3.045PheLys: 3.045 ± 2.31
5.22PheLeu: 5.22 ± 1.244
1.74PheMet: 1.74 ± 0.844
1.305PheAsn: 1.305 ± 0.497
2.175PhePro: 2.175 ± 1.471
1.305PheGln: 1.305 ± 0.633
3.045PheArg: 3.045 ± 1.014
6.525PheSer: 6.525 ± 1.191
3.045PheThr: 3.045 ± 0.59
2.175PheVal: 2.175 ± 0.772
0.0PheTrp: 0.0 ± 0.0
0.435PheTyr: 0.435 ± 0.211
0.0PheXaa: 0.0 ± 0.0
Gly
4.35GlyAla: 4.35 ± 1.524
2.61GlyCys: 2.61 ± 0.691
4.35GlyAsp: 4.35 ± 2.11
3.915GlyGlu: 3.915 ± 0.948
2.175GlyPhe: 2.175 ± 0.559
3.48GlyGly: 3.48 ± 1.561
0.87GlyHis: 0.87 ± 0.783
2.175GlyIle: 2.175 ± 0.75
3.045GlyLys: 3.045 ± 1.972
9.569GlyLeu: 9.569 ± 0.274
1.74GlyMet: 1.74 ± 0.844
3.915GlyAsn: 3.915 ± 2.362
1.74GlyPro: 1.74 ± 1.419
1.74GlyGln: 1.74 ± 0.716
3.045GlyArg: 3.045 ± 0.856
6.09GlySer: 6.09 ± 1.181
3.915GlyThr: 3.915 ± 0.7
6.09GlyVal: 6.09 ± 1.228
1.305GlyTrp: 1.305 ± 0.633
1.305GlyTyr: 1.305 ± 0.633
0.0GlyXaa: 0.0 ± 0.0
His
2.61HisAla: 2.61 ± 0.691
0.87HisCys: 0.87 ± 0.59
1.305HisAsp: 1.305 ± 1.244
1.305HisGlu: 1.305 ± 0.633
0.435HisPhe: 0.435 ± 0.211
0.435HisGly: 0.435 ± 0.211
0.435HisHis: 0.435 ± 0.211
2.175HisIle: 2.175 ± 0.75
2.175HisLys: 2.175 ± 1.055
2.61HisLeu: 2.61 ± 1.187
0.87HisMet: 0.87 ± 0.397
0.87HisAsn: 0.87 ± 0.783
0.87HisPro: 0.87 ± 0.59
0.87HisGln: 0.87 ± 0.422
1.305HisArg: 1.305 ± 1.244
2.175HisSer: 2.175 ± 1.309
0.87HisThr: 0.87 ± 0.422
0.87HisVal: 0.87 ± 0.422
0.87HisTrp: 0.87 ± 1.331
2.175HisTyr: 2.175 ± 1.055
0.0HisXaa: 0.0 ± 0.0
Ile
4.785IleAla: 4.785 ± 2.026
0.435IleCys: 0.435 ± 0.211
1.74IleAsp: 1.74 ± 0.844
2.61IleGlu: 2.61 ± 1.266
2.61IlePhe: 2.61 ± 1.266
2.61IleGly: 2.61 ± 2.144
0.435IleHis: 0.435 ± 0.211
2.61IleIle: 2.61 ± 1.266
4.35IleLys: 4.35 ± 1.063
1.74IleLeu: 1.74 ± 0.844
2.175IleMet: 2.175 ± 0.573
4.35IleAsn: 4.35 ± 1.448
0.435IlePro: 0.435 ± 0.211
1.74IleGln: 1.74 ± 0.896
2.61IleArg: 2.61 ± 0.691
3.045IleSer: 3.045 ± 1.119
2.61IleThr: 2.61 ± 0.876
1.305IleVal: 1.305 ± 0.633
0.0IleTrp: 0.0 ± 0.0
1.305IleTyr: 1.305 ± 0.497
0.0IleXaa: 0.0 ± 0.0
Lys
6.96LysAla: 6.96 ± 1.228
1.74LysCys: 1.74 ± 2.962
3.48LysAsp: 3.48 ± 1.808
6.525LysGlu: 6.525 ± 1.676
1.305LysPhe: 1.305 ± 0.497
4.35LysGly: 4.35 ± 2.98
2.175LysHis: 2.175 ± 1.169
4.35LysIle: 4.35 ± 1.193
6.09LysLys: 6.09 ± 2.239
7.829LysLeu: 7.829 ± 1.401
2.175LysMet: 2.175 ± 1.07
4.785LysAsn: 4.785 ± 1.239
0.87LysPro: 0.87 ± 0.783
1.305LysGln: 1.305 ± 1.244
3.915LysArg: 3.915 ± 1.439
3.915LysSer: 3.915 ± 2.335
2.61LysThr: 2.61 ± 1.168
5.655LysVal: 5.655 ± 1.502
0.0LysTrp: 0.0 ± 0.0
0.435LysTyr: 0.435 ± 0.733
0.0LysXaa: 0.0 ± 0.0
Leu
5.22LeuAla: 5.22 ± 1.963
1.74LeuCys: 1.74 ± 1.189
6.09LeuAsp: 6.09 ± 1.576
6.525LeuGlu: 6.525 ± 1.191
6.09LeuPhe: 6.09 ± 2.313
8.264LeuGly: 8.264 ± 1.388
2.61LeuHis: 2.61 ± 1.577
5.22LeuIle: 5.22 ± 0.841
9.569LeuLys: 9.569 ± 1.634
7.395LeuLeu: 7.395 ± 1.678
3.48LeuMet: 3.48 ± 0.969
4.785LeuAsn: 4.785 ± 1.183
2.175LeuPro: 2.175 ± 1.282
2.175LeuGln: 2.175 ± 1.055
6.96LeuArg: 6.96 ± 1.655
7.829LeuSer: 7.829 ± 0.629
3.48LeuThr: 3.48 ± 0.969
5.655LeuVal: 5.655 ± 1.375
0.0LeuTrp: 0.0 ± 0.0
2.61LeuTyr: 2.61 ± 0.691
0.0LeuXaa: 0.0 ± 0.0
Met
1.305MetAla: 1.305 ± 0.497
0.435MetCys: 0.435 ± 0.733
1.305MetAsp: 1.305 ± 0.633
4.785MetGlu: 4.785 ± 3.641
1.74MetPhe: 1.74 ± 0.485
2.61MetGly: 2.61 ± 1.718
0.0MetHis: 0.0 ± 0.0
0.87MetIle: 0.87 ± 0.59
0.435MetLys: 0.435 ± 0.211
1.305MetLeu: 1.305 ± 0.497
1.74MetMet: 1.74 ± 0.485
1.305MetAsn: 1.305 ± 1.314
1.74MetPro: 1.74 ± 0.485
0.0MetGln: 0.0 ± 0.0
2.61MetArg: 2.61 ± 1.266
3.48MetSer: 3.48 ± 0.969
1.74MetThr: 1.74 ± 0.485
1.74MetVal: 1.74 ± 0.485
0.0MetTrp: 0.0 ± 0.0
0.87MetTyr: 0.87 ± 0.59
0.0MetXaa: 0.0 ± 0.0
Asn
3.48AsnAla: 3.48 ± 1.561
0.87AsnCys: 0.87 ± 0.422
2.61AsnAsp: 2.61 ± 0.691
2.61AsnGlu: 2.61 ± 0.641
2.175AsnPhe: 2.175 ± 1.07
4.785AsnGly: 4.785 ± 1.125
0.87AsnHis: 0.87 ± 0.422
2.175AsnIle: 2.175 ± 0.772
3.045AsnLys: 3.045 ± 1.919
4.785AsnLeu: 4.785 ± 1.626
0.87AsnMet: 0.87 ± 0.59
1.305AsnAsn: 1.305 ± 1.314
3.045AsnPro: 3.045 ± 1.477
1.74AsnGln: 1.74 ± 0.485
1.74AsnArg: 1.74 ± 1.441
3.915AsnSer: 3.915 ± 1.027
1.305AsnThr: 1.305 ± 0.633
2.175AsnVal: 2.175 ± 1.282
0.435AsnTrp: 0.435 ± 0.211
1.74AsnTyr: 1.74 ± 1.189
0.0AsnXaa: 0.0 ± 0.0
Pro
3.045ProAla: 3.045 ± 0.59
0.0ProCys: 0.0 ± 0.0
2.175ProAsp: 2.175 ± 0.772
3.915ProGlu: 3.915 ± 2.362
1.305ProPhe: 1.305 ± 1.59
0.435ProGly: 0.435 ± 0.733
0.435ProHis: 0.435 ± 1.444
1.74ProIle: 1.74 ± 0.896
0.435ProLys: 0.435 ± 0.211
4.785ProLeu: 4.785 ± 1.393
0.435ProMet: 0.435 ± 0.211
2.175ProAsn: 2.175 ± 1.886
0.435ProPro: 0.435 ± 0.211
2.175ProGln: 2.175 ± 0.772
1.74ProArg: 1.74 ± 0.485
1.74ProSer: 1.74 ± 2.061
1.305ProThr: 1.305 ± 0.633
1.305ProVal: 1.305 ± 0.633
0.87ProTrp: 0.87 ± 0.422
1.305ProTyr: 1.305 ± 0.633
0.0ProXaa: 0.0 ± 0.0
Gln
1.305GlnAla: 1.305 ± 1.59
0.0GlnCys: 0.0 ± 0.0
2.175GlnAsp: 2.175 ± 1.055
2.175GlnGlu: 2.175 ± 0.559
0.435GlnPhe: 0.435 ± 0.893
3.045GlnGly: 3.045 ± 1.477
0.0GlnHis: 0.0 ± 0.0
0.435GlnIle: 0.435 ± 0.211
3.48GlnLys: 3.48 ± 0.969
3.045GlnLeu: 3.045 ± 1.285
1.74GlnMet: 1.74 ± 1.189
1.305GlnAsn: 1.305 ± 0.633
1.305GlnPro: 1.305 ± 1.314
0.435GlnGln: 0.435 ± 0.211
2.175GlnArg: 2.175 ± 0.75
4.35GlnSer: 4.35 ± 1.459
1.305GlnThr: 1.305 ± 0.633
3.48GlnVal: 3.48 ± 1.792
0.0GlnTrp: 0.0 ± 0.0
0.435GlnTyr: 0.435 ± 0.211
0.0GlnXaa: 0.0 ± 0.0
Arg
2.61ArgAla: 2.61 ± 2.814
1.305ArgCys: 1.305 ± 1.244
2.61ArgAsp: 2.61 ± 1.199
4.785ArgGlu: 4.785 ± 0.709
2.61ArgPhe: 2.61 ± 1.187
5.22ArgGly: 5.22 ± 1.454
1.305ArgHis: 1.305 ± 1.244
2.61ArgIle: 2.61 ± 1.266
4.35ArgLys: 4.35 ± 1.426
5.22ArgLeu: 5.22 ± 1.282
1.74ArgMet: 1.74 ± 1.18
3.48ArgAsn: 3.48 ± 1.038
0.435ArgPro: 0.435 ± 1.444
1.74ArgGln: 1.74 ± 0.896
3.915ArgArg: 3.915 ± 2.507
4.785ArgSer: 4.785 ± 1.215
2.175ArgThr: 2.175 ± 1.49
3.48ArgVal: 3.48 ± 0.969
0.87ArgTrp: 0.87 ± 0.422
2.175ArgTyr: 2.175 ± 1.055
0.0ArgXaa: 0.0 ± 0.0
Ser
3.915SerAla: 3.915 ± 2.507
2.61SerCys: 2.61 ± 0.691
3.915SerAsp: 3.915 ± 1.024
6.96SerGlu: 6.96 ± 1.394
6.96SerPhe: 6.96 ± 1.354
5.655SerGly: 5.655 ± 2.42
3.915SerHis: 3.915 ± 1.439
3.045SerIle: 3.045 ± 1.477
5.655SerLys: 5.655 ± 2.015
6.09SerLeu: 6.09 ± 1.55
1.305SerMet: 1.305 ± 1.314
3.915SerAsn: 3.915 ± 1.071
3.48SerPro: 3.48 ± 1.327
2.61SerGln: 2.61 ± 1.47
5.22SerArg: 5.22 ± 1.916
4.35SerSer: 4.35 ± 1.108
3.045SerThr: 3.045 ± 1.014
5.22SerVal: 5.22 ± 2.688
0.0SerTrp: 0.0 ± 0.0
4.785SerTyr: 4.785 ± 1.408
0.0SerXaa: 0.0 ± 0.0
Thr
1.305ThrAla: 1.305 ± 0.72
0.435ThrCys: 0.435 ± 0.211
1.74ThrAsp: 1.74 ± 0.485
3.045ThrGlu: 3.045 ± 1.762
2.175ThrPhe: 2.175 ± 1.055
1.74ThrGly: 1.74 ± 0.485
0.87ThrHis: 0.87 ± 0.422
1.305ThrIle: 1.305 ± 0.633
3.045ThrLys: 3.045 ± 0.59
4.785ThrLeu: 4.785 ± 2.026
2.175ThrMet: 2.175 ± 0.559
1.74ThrAsn: 1.74 ± 0.844
2.175ThrPro: 2.175 ± 1.282
1.305ThrGln: 1.305 ± 0.633
3.045ThrArg: 3.045 ± 0.59
4.785ThrSer: 4.785 ± 0.994
1.305ThrThr: 1.305 ± 0.497
2.61ThrVal: 2.61 ± 0.691
0.87ThrTrp: 0.87 ± 0.783
0.87ThrTyr: 0.87 ± 0.422
0.0ThrXaa: 0.0 ± 0.0
Val
3.915ValAla: 3.915 ± 1.899
4.35ValCys: 4.35 ± 0.834
2.61ValAsp: 2.61 ± 1.187
3.48ValGlu: 3.48 ± 1.109
3.045ValPhe: 3.045 ± 1.451
5.22ValGly: 5.22 ± 1.171
3.48ValHis: 3.48 ± 0.969
2.61ValIle: 2.61 ± 1.441
4.35ValLys: 4.35 ± 2.355
6.96ValLeu: 6.96 ± 1.932
1.74ValMet: 1.74 ± 2.045
2.175ValAsn: 2.175 ± 0.559
0.0ValPro: 0.0 ± 0.0
1.74ValGln: 1.74 ± 0.485
2.61ValArg: 2.61 ± 0.994
6.525ValSer: 6.525 ± 1.723
1.305ValThr: 1.305 ± 1.064
5.655ValVal: 5.655 ± 1.944
0.435ValTrp: 0.435 ± 0.211
1.305ValTyr: 1.305 ± 0.72
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.435TrpCys: 0.435 ± 0.211
0.0TrpAsp: 0.0 ± 0.0
0.435TrpGlu: 0.435 ± 0.211
0.87TrpPhe: 0.87 ± 0.422
0.87TrpGly: 0.87 ± 0.783
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.87TrpLys: 0.87 ± 0.422
1.74TrpLeu: 1.74 ± 2.663
0.0TrpMet: 0.0 ± 0.0
0.435TrpAsn: 0.435 ± 0.211
1.305TrpPro: 1.305 ± 0.633
0.435TrpGln: 0.435 ± 0.211
0.435TrpArg: 0.435 ± 0.211
1.74TrpSer: 1.74 ± 1.189
0.0TrpThr: 0.0 ± 0.0
0.87TrpVal: 0.87 ± 0.422
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.87TyrAla: 0.87 ± 0.422
0.0TyrCys: 0.0 ± 0.0
2.175TyrAsp: 2.175 ± 0.559
3.915TyrGlu: 3.915 ± 1.899
0.0TyrPhe: 0.0 ± 0.0
1.305TyrGly: 1.305 ± 0.633
0.435TyrHis: 0.435 ± 1.444
0.0TyrIle: 0.0 ± 0.0
0.435TyrLys: 0.435 ± 0.211
5.22TyrLeu: 5.22 ± 1.288
0.87TyrMet: 0.87 ± 1.349
1.74TyrAsn: 1.74 ± 1.189
1.74TyrPro: 1.74 ± 0.896
0.435TyrGln: 0.435 ± 0.733
2.61TyrArg: 2.61 ± 1.266
3.045TyrSer: 3.045 ± 1.014
3.045TyrThr: 3.045 ± 1.014
2.61TyrVal: 2.61 ± 1.266
0.435TyrTrp: 0.435 ± 0.211
1.305TyrTyr: 1.305 ± 1.244
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2300 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski