Amino acid dipepetide frequency for Cherry associated luteovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.25AlaAla: 5.25 ± 1.149
0.808AlaCys: 0.808 ± 0.437
0.808AlaAsp: 0.808 ± 0.437
6.058AlaGlu: 6.058 ± 1.806
2.423AlaPhe: 2.423 ± 0.484
2.827AlaGly: 2.827 ± 1.867
1.212AlaHis: 1.212 ± 0.572
2.827AlaIle: 2.827 ± 0.967
5.654AlaLys: 5.654 ± 1.102
4.847AlaLeu: 4.847 ± 1.648
2.827AlaMet: 2.827 ± 1.14
2.423AlaAsn: 2.423 ± 0.863
2.019AlaPro: 2.019 ± 0.957
1.212AlaGln: 1.212 ± 0.324
4.847AlaArg: 4.847 ± 1.128
4.847AlaSer: 4.847 ± 0.954
1.616AlaThr: 1.616 ± 1.051
2.423AlaVal: 2.423 ± 1.062
0.404AlaTrp: 0.404 ± 0.281
2.423AlaTyr: 2.423 ± 0.537
0.0AlaXaa: 0.0 ± 0.0
Cys
1.212CysAla: 1.212 ± 0.572
0.404CysCys: 0.404 ± 0.544
1.616CysAsp: 1.616 ± 0.874
0.808CysGlu: 0.808 ± 0.354
0.404CysPhe: 0.404 ± 0.384
0.404CysGly: 0.404 ± 0.281
0.808CysHis: 0.808 ± 0.437
0.404CysIle: 0.404 ± 0.281
2.423CysLys: 2.423 ± 0.583
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.808CysAsn: 0.808 ± 0.354
0.404CysPro: 0.404 ± 0.281
0.404CysGln: 0.404 ± 0.281
1.212CysArg: 1.212 ± 0.791
1.212CysSer: 1.212 ± 0.924
0.404CysThr: 0.404 ± 0.281
1.212CysVal: 1.212 ± 0.572
0.0CysTrp: 0.0 ± 0.0
0.808CysTyr: 0.808 ± 0.627
0.0CysXaa: 0.0 ± 0.0
Asp
3.635AspAla: 3.635 ± 1.326
1.212AspCys: 1.212 ± 0.572
4.039AspAsp: 4.039 ± 0.886
3.231AspGlu: 3.231 ± 1.114
2.827AspPhe: 2.827 ± 1.403
2.827AspGly: 2.827 ± 0.842
0.0AspHis: 0.0 ± 0.0
3.231AspIle: 3.231 ± 1.27
2.019AspLys: 2.019 ± 0.499
6.866AspLeu: 6.866 ± 1.389
2.019AspMet: 2.019 ± 1.019
2.019AspAsn: 2.019 ± 0.577
4.039AspPro: 4.039 ± 1.157
3.635AspGln: 3.635 ± 0.458
2.423AspArg: 2.423 ± 0.863
3.635AspSer: 3.635 ± 0.993
3.231AspThr: 3.231 ± 0.749
2.827AspVal: 2.827 ± 0.768
0.808AspTrp: 0.808 ± 0.768
1.212AspTyr: 1.212 ± 0.324
0.404AspXaa: 0.404 ± 0.384
Glu
4.847GluAla: 4.847 ± 0.796
0.0GluCys: 0.0 ± 0.0
6.058GluAsp: 6.058 ± 1.341
3.231GluGlu: 3.231 ± 1.934
1.616GluPhe: 1.616 ± 0.374
1.616GluGly: 1.616 ± 1.129
1.212GluHis: 1.212 ± 0.572
2.827GluIle: 2.827 ± 1.07
4.039GluLys: 4.039 ± 1.079
4.847GluLeu: 4.847 ± 1.402
0.404GluMet: 0.404 ± 0.492
1.616GluAsn: 1.616 ± 0.374
2.827GluPro: 2.827 ± 1.135
2.423GluGln: 2.423 ± 0.583
3.231GluArg: 3.231 ± 0.889
3.635GluSer: 3.635 ± 0.585
2.827GluThr: 2.827 ± 0.88
4.039GluVal: 4.039 ± 1.359
1.616GluTrp: 1.616 ± 0.584
2.019GluTyr: 2.019 ± 0.609
0.0GluXaa: 0.0 ± 0.0
Phe
2.423PheAla: 2.423 ± 0.491
2.423PheCys: 2.423 ± 1.143
2.423PheAsp: 2.423 ± 1.085
3.231PheGlu: 3.231 ± 1.147
1.212PhePhe: 1.212 ± 0.831
4.039PheGly: 4.039 ± 0.857
1.212PheHis: 1.212 ± 0.737
2.827PheIle: 2.827 ± 0.98
2.019PheLys: 2.019 ± 0.577
3.635PheLeu: 3.635 ± 2.011
2.019PheMet: 2.019 ± 1.469
2.019PheAsn: 2.019 ± 0.682
0.808PhePro: 0.808 ± 0.548
3.231PheGln: 3.231 ± 1.109
2.827PheArg: 2.827 ± 1.091
4.847PheSer: 4.847 ± 1.507
4.443PheThr: 4.443 ± 2.322
4.039PheVal: 4.039 ± 1.16
0.404PheTrp: 0.404 ± 0.587
0.808PheTyr: 0.808 ± 0.695
0.0PheXaa: 0.0 ± 0.0
Gly
2.827GlyAla: 2.827 ± 0.565
0.0GlyCys: 0.0 ± 0.0
3.635GlyAsp: 3.635 ± 1.608
4.443GlyGlu: 4.443 ± 1.759
4.039GlyPhe: 4.039 ± 1.2
5.654GlyGly: 5.654 ± 2.083
1.616GlyHis: 1.616 ± 0.671
2.423GlyIle: 2.423 ± 1.402
6.866GlyLys: 6.866 ± 2.419
2.423GlyLeu: 2.423 ± 0.729
0.404GlyMet: 0.404 ± 0.281
3.231GlyAsn: 3.231 ± 1.735
4.847GlyPro: 4.847 ± 2.013
3.231GlyGln: 3.231 ± 0.631
7.27GlyArg: 7.27 ± 1.786
4.847GlySer: 4.847 ± 1.138
2.423GlyThr: 2.423 ± 1.048
5.25GlyVal: 5.25 ± 1.634
0.404GlyTrp: 0.404 ± 0.544
1.616GlyTyr: 1.616 ± 0.708
0.0GlyXaa: 0.0 ± 0.0
His
2.019HisAla: 2.019 ± 1.035
0.0HisCys: 0.0 ± 0.0
1.212HisAsp: 1.212 ± 0.324
0.808HisGlu: 0.808 ± 0.548
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.212HisHis: 1.212 ± 0.324
0.0HisIle: 0.0 ± 0.0
0.404HisLys: 0.404 ± 0.384
0.808HisLeu: 0.808 ± 0.56
0.0HisMet: 0.0 ± 0.0
2.423HisAsn: 2.423 ± 0.826
1.212HisPro: 1.212 ± 0.444
0.0HisGln: 0.0 ± 0.0
0.404HisArg: 0.404 ± 0.281
2.827HisSer: 2.827 ± 1.24
0.0HisThr: 0.0 ± 0.0
2.019HisVal: 2.019 ± 0.604
0.404HisTrp: 0.404 ± 0.281
0.808HisTyr: 0.808 ± 0.437
0.0HisXaa: 0.0 ± 0.0
Ile
3.231IleAla: 3.231 ± 1.486
0.808IleCys: 0.808 ± 0.561
2.423IleAsp: 2.423 ± 0.423
4.443IleGlu: 4.443 ± 0.68
2.827IlePhe: 2.827 ± 1.105
3.635IleGly: 3.635 ± 1.075
2.423IleHis: 2.423 ± 1.204
2.423IleIle: 2.423 ± 0.715
2.019IleLys: 2.019 ± 0.35
4.443IleLeu: 4.443 ± 0.968
0.808IleMet: 0.808 ± 0.533
2.827IleAsn: 2.827 ± 1.14
3.231IlePro: 3.231 ± 0.838
2.019IleGln: 2.019 ± 0.604
4.039IleArg: 4.039 ± 0.927
4.039IleSer: 4.039 ± 1.048
1.212IleThr: 1.212 ± 0.831
5.25IleVal: 5.25 ± 1.024
0.808IleTrp: 0.808 ± 0.548
1.616IleTyr: 1.616 ± 0.615
0.0IleXaa: 0.0 ± 0.0
Lys
4.847LysAla: 4.847 ± 0.928
0.808LysCys: 0.808 ± 0.437
4.443LysAsp: 4.443 ± 1.646
2.423LysGlu: 2.423 ± 1.005
7.27LysPhe: 7.27 ± 1.133
8.078LysGly: 8.078 ± 3.337
0.404LysHis: 0.404 ± 0.281
2.423LysIle: 2.423 ± 0.796
5.25LysLys: 5.25 ± 0.803
4.443LysLeu: 4.443 ± 2.29
1.212LysMet: 1.212 ± 0.71
1.616LysAsn: 1.616 ± 0.654
0.404LysPro: 0.404 ± 0.384
3.635LysGln: 3.635 ± 1.07
2.423LysArg: 2.423 ± 0.583
3.635LysSer: 3.635 ± 0.547
1.212LysThr: 1.212 ± 0.684
5.25LysVal: 5.25 ± 1.18
2.423LysTrp: 2.423 ± 0.826
2.827LysTyr: 2.827 ± 1.08
0.0LysXaa: 0.0 ± 0.0
Leu
3.635LeuAla: 3.635 ± 1.028
2.423LeuCys: 2.423 ± 1.354
5.25LeuAsp: 5.25 ± 0.925
4.039LeuGlu: 4.039 ± 1.205
4.039LeuPhe: 4.039 ± 1.207
5.25LeuGly: 5.25 ± 1.094
0.404LeuHis: 0.404 ± 0.281
6.058LeuIle: 6.058 ± 0.579
4.847LeuLys: 4.847 ± 1.213
6.866LeuLeu: 6.866 ± 2.475
3.231LeuMet: 3.231 ± 0.951
2.423LeuAsn: 2.423 ± 0.583
4.039LeuPro: 4.039 ± 0.928
4.039LeuGln: 4.039 ± 1.084
5.654LeuArg: 5.654 ± 1.714
5.654LeuSer: 5.654 ± 2.339
3.231LeuThr: 3.231 ± 1.403
4.847LeuVal: 4.847 ± 1.418
0.404LeuTrp: 0.404 ± 0.492
1.212LeuTyr: 1.212 ± 0.572
0.0LeuXaa: 0.0 ± 0.0
Met
0.808MetAla: 0.808 ± 0.508
1.212MetCys: 1.212 ± 0.572
0.808MetAsp: 0.808 ± 0.437
2.827MetGlu: 2.827 ± 0.444
0.808MetPhe: 0.808 ± 0.96
2.019MetGly: 2.019 ± 1.369
0.808MetHis: 0.808 ± 0.561
0.808MetIle: 0.808 ± 0.354
3.231MetLys: 3.231 ± 1.034
2.827MetLeu: 2.827 ± 1.215
0.0MetMet: 0.0 ± 0.0
0.404MetAsn: 0.404 ± 0.587
1.212MetPro: 1.212 ± 0.831
0.808MetGln: 0.808 ± 0.54
0.808MetArg: 0.808 ± 0.437
1.212MetSer: 1.212 ± 0.511
1.212MetThr: 1.212 ± 0.572
4.039MetVal: 4.039 ± 1.887
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.423AsnAla: 2.423 ± 0.484
1.616AsnCys: 1.616 ± 0.561
3.635AsnAsp: 3.635 ± 1.456
1.212AsnGlu: 1.212 ± 0.684
2.423AsnPhe: 2.423 ± 1.203
3.231AsnGly: 3.231 ± 1.388
0.404AsnHis: 0.404 ± 0.384
1.616AsnIle: 1.616 ± 0.698
0.808AsnLys: 0.808 ± 0.561
2.019AsnLeu: 2.019 ± 0.591
0.808AsnMet: 0.808 ± 0.627
2.423AsnAsn: 2.423 ± 1.807
3.231AsnPro: 3.231 ± 1.212
0.404AsnGln: 0.404 ± 0.492
3.231AsnArg: 3.231 ± 0.904
3.635AsnSer: 3.635 ± 1.372
1.212AsnThr: 1.212 ± 0.572
3.635AsnVal: 3.635 ± 0.993
0.404AsnTrp: 0.404 ± 0.384
1.616AsnTyr: 1.616 ± 0.708
0.404AsnXaa: 0.404 ± 0.281
Pro
2.827ProAla: 2.827 ± 1.06
0.404ProCys: 0.404 ± 0.384
3.231ProAsp: 3.231 ± 0.824
2.827ProGlu: 2.827 ± 1.197
0.808ProPhe: 0.808 ± 0.561
3.231ProGly: 3.231 ± 1.753
0.0ProHis: 0.0 ± 0.0
5.25ProIle: 5.25 ± 2.147
1.212ProLys: 1.212 ± 0.726
3.231ProLeu: 3.231 ± 0.734
2.827ProMet: 2.827 ± 0.612
2.019ProAsn: 2.019 ± 0.755
5.25ProPro: 5.25 ± 1.825
4.039ProGln: 4.039 ± 0.864
2.423ProArg: 2.423 ± 1.198
4.039ProSer: 4.039 ± 2.112
4.847ProThr: 4.847 ± 1.075
5.25ProVal: 5.25 ± 1.037
0.0ProTrp: 0.0 ± 0.0
1.212ProTyr: 1.212 ± 0.76
0.404ProXaa: 0.404 ± 0.281
Gln
3.635GlnAla: 3.635 ± 1.024
0.404GlnCys: 0.404 ± 0.281
0.808GlnAsp: 0.808 ± 0.768
2.423GlnGlu: 2.423 ± 1.35
3.635GlnPhe: 3.635 ± 0.708
3.231GlnGly: 3.231 ± 0.757
1.212GlnHis: 1.212 ± 0.572
1.212GlnIle: 1.212 ± 0.609
2.827GlnLys: 2.827 ± 1.201
2.423GlnLeu: 2.423 ± 0.62
1.616GlnMet: 1.616 ± 0.768
2.423GlnAsn: 2.423 ± 0.649
3.231GlnPro: 3.231 ± 1.262
0.0GlnGln: 0.0 ± 0.0
0.808GlnArg: 0.808 ± 0.768
5.654GlnSer: 5.654 ± 1.592
2.423GlnThr: 2.423 ± 0.543
4.443GlnVal: 4.443 ± 0.982
0.808GlnTrp: 0.808 ± 0.984
1.616GlnTyr: 1.616 ± 0.698
0.404GlnXaa: 0.404 ± 0.384
Arg
2.827ArgAla: 2.827 ± 0.728
0.0ArgCys: 0.0 ± 0.0
3.231ArgAsp: 3.231 ± 0.763
2.423ArgGlu: 2.423 ± 0.808
2.827ArgPhe: 2.827 ± 0.74
5.25ArgGly: 5.25 ± 1.979
0.0ArgHis: 0.0 ± 0.0
4.443ArgIle: 4.443 ± 1.049
4.039ArgLys: 4.039 ± 1.344
8.885ArgLeu: 8.885 ± 2.201
1.616ArgMet: 1.616 ± 0.603
1.616ArgAsn: 1.616 ± 1.173
2.827ArgPro: 2.827 ± 0.853
2.423ArgGln: 2.423 ± 0.641
6.058ArgArg: 6.058 ± 2.025
6.866ArgSer: 6.866 ± 2.354
1.616ArgThr: 1.616 ± 0.873
3.231ArgVal: 3.231 ± 0.758
0.808ArgTrp: 0.808 ± 0.437
3.231ArgTyr: 3.231 ± 0.749
0.0ArgXaa: 0.0 ± 0.0
Ser
1.616SerAla: 1.616 ± 0.788
0.808SerCys: 0.808 ± 0.567
2.423SerAsp: 2.423 ± 1.007
2.827SerGlu: 2.827 ± 0.702
6.058SerPhe: 6.058 ± 1.894
6.866SerGly: 6.866 ± 1.417
0.808SerHis: 0.808 ± 0.354
4.847SerIle: 4.847 ± 1.506
2.827SerLys: 2.827 ± 0.71
5.654SerLeu: 5.654 ± 0.994
1.212SerMet: 1.212 ± 0.511
2.423SerAsn: 2.423 ± 1.398
5.25SerPro: 5.25 ± 1.329
4.443SerGln: 4.443 ± 1.766
7.674SerArg: 7.674 ± 2.219
9.289SerSer: 9.289 ± 5.156
8.078SerThr: 8.078 ± 2.998
5.25SerVal: 5.25 ± 2.266
0.404SerTrp: 0.404 ± 0.384
3.635SerTyr: 3.635 ± 0.604
0.0SerXaa: 0.0 ± 0.0
Thr
1.616ThrAla: 1.616 ± 0.744
0.404ThrCys: 0.404 ± 0.384
1.616ThrAsp: 1.616 ± 0.374
1.616ThrGlu: 1.616 ± 0.914
1.616ThrPhe: 1.616 ± 0.41
3.635ThrGly: 3.635 ± 0.8
0.404ThrHis: 0.404 ± 0.281
3.231ThrIle: 3.231 ± 1.188
2.827ThrLys: 2.827 ± 1.345
3.231ThrLeu: 3.231 ± 1.295
2.019ThrMet: 2.019 ± 0.541
2.019ThrAsn: 2.019 ± 0.734
2.423ThrPro: 2.423 ± 1.279
2.423ThrGln: 2.423 ± 0.927
3.635ThrArg: 3.635 ± 1.507
4.443ThrSer: 4.443 ± 1.758
2.827ThrThr: 2.827 ± 0.963
5.25ThrVal: 5.25 ± 1.09
1.212ThrTrp: 1.212 ± 0.924
0.808ThrTyr: 0.808 ± 0.508
0.0ThrXaa: 0.0 ± 0.0
Val
4.443ValAla: 4.443 ± 1.04
0.808ValCys: 0.808 ± 0.768
6.058ValAsp: 6.058 ± 1.061
4.847ValGlu: 4.847 ± 1.554
2.827ValPhe: 2.827 ± 1.347
3.635ValGly: 3.635 ± 1.035
0.808ValHis: 0.808 ± 0.56
6.462ValIle: 6.462 ± 1.124
7.674ValLys: 7.674 ± 2.246
4.039ValLeu: 4.039 ± 0.957
1.212ValMet: 1.212 ± 0.324
2.827ValAsn: 2.827 ± 1.606
6.462ValPro: 6.462 ± 1.114
5.25ValGln: 5.25 ± 1.473
2.423ValArg: 2.423 ± 0.726
6.462ValSer: 6.462 ± 1.66
3.635ValThr: 3.635 ± 1.047
5.25ValVal: 5.25 ± 2.597
0.0ValTrp: 0.0 ± 0.0
2.827ValTyr: 2.827 ± 0.922
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.404TrpAsp: 0.404 ± 0.544
0.404TrpGlu: 0.404 ± 0.281
0.808TrpPhe: 0.808 ± 0.686
0.0TrpGly: 0.0 ± 0.0
1.212TrpHis: 1.212 ± 0.444
0.0TrpIle: 0.0 ± 0.0
0.808TrpLys: 0.808 ± 0.627
2.423TrpLeu: 2.423 ± 0.543
0.0TrpMet: 0.0 ± 0.0
0.404TrpAsn: 0.404 ± 0.384
1.212TrpPro: 1.212 ± 0.609
0.404TrpGln: 0.404 ± 0.281
0.808TrpArg: 0.808 ± 0.354
0.808TrpSer: 0.808 ± 0.79
0.404TrpThr: 0.404 ± 0.492
0.808TrpVal: 0.808 ± 0.437
0.0TrpTrp: 0.0 ± 0.0
0.808TrpTyr: 0.808 ± 0.768
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.635TyrAla: 3.635 ± 0.915
0.404TyrCys: 0.404 ± 0.384
1.616TyrAsp: 1.616 ± 0.374
0.404TyrGlu: 0.404 ± 0.281
2.827TyrPhe: 2.827 ± 1.454
2.019TyrGly: 2.019 ± 0.577
0.404TyrHis: 0.404 ± 0.281
1.212TyrIle: 1.212 ± 0.774
3.231TyrLys: 3.231 ± 0.782
3.635TyrLeu: 3.635 ± 0.691
1.212TyrMet: 1.212 ± 0.324
2.423TyrAsn: 2.423 ± 0.927
0.0TyrPro: 0.0 ± 0.0
1.212TyrGln: 1.212 ± 0.684
2.019TyrArg: 2.019 ± 0.649
0.808TyrSer: 0.808 ± 0.54
0.404TyrThr: 0.404 ± 0.384
3.231TyrVal: 3.231 ± 0.954
0.404TyrTrp: 0.404 ± 0.281
0.404TyrTyr: 0.404 ± 0.587
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.404XaaAsp: 0.404 ± 0.384
0.404XaaGlu: 0.404 ± 0.281
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.404XaaPro: 0.404 ± 0.281
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.404XaaVal: 0.404 ± 0.384
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.808XaaXaa: 0.808 ± 0.561
Statistics based on 8 proteins (2477 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski