Amino acid dipepetide frequency for Pea early browning virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.658AlaAla: 6.658 ± 1.59
0.74AlaCys: 0.74 ± 0.313
4.439AlaAsp: 4.439 ± 0.975
3.699AlaGlu: 3.699 ± 0.409
3.206AlaPhe: 3.206 ± 1.15
1.973AlaGly: 1.973 ± 0.719
1.48AlaHis: 1.48 ± 0.389
2.713AlaIle: 2.713 ± 0.652
3.946AlaLys: 3.946 ± 0.548
6.658AlaLeu: 6.658 ± 1.554
3.453AlaMet: 3.453 ± 0.616
3.699AlaAsn: 3.699 ± 0.676
1.973AlaPro: 1.973 ± 0.532
3.946AlaGln: 3.946 ± 0.755
2.219AlaArg: 2.219 ± 0.501
2.713AlaSer: 2.713 ± 1.254
3.699AlaThr: 3.699 ± 0.639
3.453AlaVal: 3.453 ± 0.477
1.48AlaTrp: 1.48 ± 0.476
2.466AlaTyr: 2.466 ± 0.632
0.0AlaXaa: 0.0 ± 0.0
Cys
2.466CysAla: 2.466 ± 0.772
0.247CysCys: 0.247 ± 0.337
0.493CysAsp: 0.493 ± 0.588
0.74CysGlu: 0.74 ± 0.666
0.0CysPhe: 0.0 ± 0.0
1.726CysGly: 1.726 ± 0.687
0.0CysHis: 0.0 ± 0.0
0.493CysIle: 0.493 ± 0.351
1.48CysLys: 1.48 ± 0.389
1.973CysLeu: 1.973 ± 0.714
0.247CysMet: 0.247 ± 0.303
1.726CysAsn: 1.726 ± 0.62
0.986CysPro: 0.986 ± 0.374
0.986CysGln: 0.986 ± 0.374
1.233CysArg: 1.233 ± 0.442
2.466CysSer: 2.466 ± 0.774
0.74CysThr: 0.74 ± 0.276
2.466CysVal: 2.466 ± 0.436
0.0CysTrp: 0.0 ± 0.0
0.986CysTyr: 0.986 ± 0.452
0.0CysXaa: 0.0 ± 0.0
Asp
4.932AspAla: 4.932 ± 1.169
2.219AspCys: 2.219 ± 0.58
6.905AspAsp: 6.905 ± 1.036
4.686AspGlu: 4.686 ± 1.312
3.206AspPhe: 3.206 ± 1.246
5.672AspGly: 5.672 ± 0.354
0.0AspHis: 0.0 ± 0.0
4.192AspIle: 4.192 ± 0.709
4.932AspLys: 4.932 ± 1.063
5.919AspLeu: 5.919 ± 2.148
0.986AspMet: 0.986 ± 0.374
1.973AspAsn: 1.973 ± 0.932
1.973AspPro: 1.973 ± 0.604
2.713AspGln: 2.713 ± 0.41
2.466AspArg: 2.466 ± 1.24
6.412AspSer: 6.412 ± 0.785
3.946AspThr: 3.946 ± 0.707
9.371AspVal: 9.371 ± 1.507
0.986AspTrp: 0.986 ± 0.415
2.219AspTyr: 2.219 ± 0.556
0.0AspXaa: 0.0 ± 0.0
Glu
5.425GluAla: 5.425 ± 1.006
0.493GluCys: 0.493 ± 0.349
3.206GluAsp: 3.206 ± 0.996
1.973GluGlu: 1.973 ± 0.874
2.713GluPhe: 2.713 ± 0.578
2.713GluGly: 2.713 ± 0.369
0.986GluHis: 0.986 ± 0.521
4.192GluIle: 4.192 ± 1.294
8.631GluLys: 8.631 ± 0.803
4.439GluLeu: 4.439 ± 0.937
2.219GluMet: 2.219 ± 0.668
1.233GluAsn: 1.233 ± 0.857
2.219GluPro: 2.219 ± 0.656
1.726GluGln: 1.726 ± 0.451
3.206GluArg: 3.206 ± 0.703
3.453GluSer: 3.453 ± 0.742
3.206GluThr: 3.206 ± 0.473
5.919GluVal: 5.919 ± 1.018
0.247GluTrp: 0.247 ± 0.165
1.973GluTyr: 1.973 ± 0.457
0.0GluXaa: 0.0 ± 0.0
Phe
2.466PheAla: 2.466 ± 0.779
1.233PheCys: 1.233 ± 0.462
6.165PheAsp: 6.165 ± 1.464
2.959PheGlu: 2.959 ± 0.743
1.48PhePhe: 1.48 ± 0.561
3.699PheGly: 3.699 ± 0.573
0.74PheHis: 0.74 ± 0.698
1.726PheIle: 1.726 ± 0.436
4.439PheLys: 4.439 ± 1.178
5.672PheLeu: 5.672 ± 0.792
1.48PheMet: 1.48 ± 0.307
3.699PheAsn: 3.699 ± 1.334
1.233PhePro: 1.233 ± 0.393
0.493PheGln: 0.493 ± 0.187
1.726PheArg: 1.726 ± 0.559
3.453PheSer: 3.453 ± 2.185
3.206PheThr: 3.206 ± 0.807
3.946PheVal: 3.946 ± 0.805
0.493PheTrp: 0.493 ± 0.187
1.233PheTyr: 1.233 ± 0.549
0.0PheXaa: 0.0 ± 0.0
Gly
2.713GlyAla: 2.713 ± 0.444
0.493GlyCys: 0.493 ± 0.187
5.179GlyAsp: 5.179 ± 1.107
1.48GlyGlu: 1.48 ± 0.925
2.219GlyPhe: 2.219 ± 0.5
2.713GlyGly: 2.713 ± 1.304
0.493GlyHis: 0.493 ± 0.187
2.466GlyIle: 2.466 ± 0.8
6.658GlyLys: 6.658 ± 1.316
4.686GlyLeu: 4.686 ± 0.741
1.48GlyMet: 1.48 ± 0.47
3.206GlyAsn: 3.206 ± 0.91
1.48GlyPro: 1.48 ± 0.834
1.973GlyGln: 1.973 ± 0.394
1.48GlyArg: 1.48 ± 0.365
4.192GlySer: 4.192 ± 1.778
2.466GlyThr: 2.466 ± 0.552
2.959GlyVal: 2.959 ± 0.924
1.48GlyTrp: 1.48 ± 0.427
2.466GlyTyr: 2.466 ± 0.696
0.0GlyXaa: 0.0 ± 0.0
His
1.726HisAla: 1.726 ± 0.374
0.493HisCys: 0.493 ± 0.187
0.986HisAsp: 0.986 ± 0.296
1.726HisGlu: 1.726 ± 0.686
1.48HisPhe: 1.48 ± 0.348
0.986HisGly: 0.986 ± 0.374
0.493HisHis: 0.493 ± 0.311
0.74HisIle: 0.74 ± 0.276
0.986HisLys: 0.986 ± 1.246
1.233HisLeu: 1.233 ± 0.836
0.247HisMet: 0.247 ± 0.165
0.247HisAsn: 0.247 ± 0.38
0.493HisPro: 0.493 ± 0.329
0.0HisGln: 0.0 ± 0.0
0.247HisArg: 0.247 ± 0.427
1.973HisSer: 1.973 ± 0.597
0.493HisThr: 0.493 ± 0.187
1.233HisVal: 1.233 ± 0.354
0.0HisTrp: 0.0 ± 0.0
0.493HisTyr: 0.493 ± 0.187
0.0HisXaa: 0.0 ± 0.0
Ile
3.699IleAla: 3.699 ± 0.796
1.233IleCys: 1.233 ± 0.354
4.932IleAsp: 4.932 ± 1.023
4.686IleGlu: 4.686 ± 0.786
2.713IlePhe: 2.713 ± 0.554
2.713IleGly: 2.713 ± 0.679
1.973IleHis: 1.973 ± 0.532
1.48IleIle: 1.48 ± 0.415
2.219IleLys: 2.219 ± 1.344
1.48IleLeu: 1.48 ± 0.35
0.74IleMet: 0.74 ± 0.307
2.959IleAsn: 2.959 ± 0.797
0.74IlePro: 0.74 ± 0.958
1.48IleGln: 1.48 ± 1.005
3.206IleArg: 3.206 ± 1.003
3.946IleSer: 3.946 ± 0.536
1.726IleThr: 1.726 ± 0.493
3.206IleVal: 3.206 ± 0.601
0.74IleTrp: 0.74 ± 0.612
1.48IleTyr: 1.48 ± 0.725
0.0IleXaa: 0.0 ± 0.0
Lys
4.439LysAla: 4.439 ± 0.616
2.466LysCys: 2.466 ± 0.987
3.206LysAsp: 3.206 ± 0.66
7.645LysGlu: 7.645 ± 1.058
5.919LysPhe: 5.919 ± 1.453
4.932LysGly: 4.932 ± 1.495
0.986LysHis: 0.986 ± 0.754
4.192LysIle: 4.192 ± 0.546
6.658LysLys: 6.658 ± 1.22
6.905LysLeu: 6.905 ± 1.054
1.48LysMet: 1.48 ± 0.542
2.466LysAsn: 2.466 ± 0.545
2.959LysPro: 2.959 ± 0.87
2.713LysGln: 2.713 ± 0.769
5.179LysArg: 5.179 ± 1.363
5.179LysSer: 5.179 ± 0.991
3.946LysThr: 3.946 ± 0.811
4.932LysVal: 4.932 ± 1.477
1.48LysTrp: 1.48 ± 0.553
2.466LysTyr: 2.466 ± 0.726
0.247LysXaa: 0.247 ± 0.165
Leu
5.425LeuAla: 5.425 ± 1.246
1.233LeuCys: 1.233 ± 0.442
5.425LeuAsp: 5.425 ± 0.767
5.179LeuGlu: 5.179 ± 0.763
3.453LeuPhe: 3.453 ± 0.789
2.713LeuGly: 2.713 ± 0.679
2.466LeuHis: 2.466 ± 0.885
5.425LeuIle: 5.425 ± 0.807
6.412LeuLys: 6.412 ± 0.619
10.111LeuLeu: 10.111 ± 1.545
4.686LeuMet: 4.686 ± 0.951
4.439LeuAsn: 4.439 ± 1.692
2.219LeuPro: 2.219 ± 0.978
4.439LeuGln: 4.439 ± 0.774
7.152LeuArg: 7.152 ± 1.215
5.919LeuSer: 5.919 ± 0.581
6.165LeuThr: 6.165 ± 0.768
4.932LeuVal: 4.932 ± 1.067
0.986LeuTrp: 0.986 ± 0.602
1.726LeuTyr: 1.726 ± 0.553
0.0LeuXaa: 0.0 ± 0.0
Met
1.726MetAla: 1.726 ± 0.451
0.493MetCys: 0.493 ± 0.351
1.973MetAsp: 1.973 ± 0.753
1.973MetGlu: 1.973 ± 0.399
1.726MetPhe: 1.726 ± 0.399
0.74MetGly: 0.74 ± 0.307
0.493MetHis: 0.493 ± 0.187
2.219MetIle: 2.219 ± 0.345
1.48MetLys: 1.48 ± 1.092
0.986MetLeu: 0.986 ± 0.374
0.493MetMet: 0.493 ± 0.187
0.247MetAsn: 0.247 ± 0.38
0.247MetPro: 0.247 ± 0.165
1.726MetGln: 1.726 ± 0.428
1.973MetArg: 1.973 ± 0.748
1.233MetSer: 1.233 ± 0.354
3.206MetThr: 3.206 ± 0.663
2.959MetVal: 2.959 ± 0.307
0.0MetTrp: 0.0 ± 0.0
0.986MetTyr: 0.986 ± 0.374
0.0MetXaa: 0.0 ± 0.0
Asn
2.219AsnAla: 2.219 ± 0.345
2.219AsnCys: 2.219 ± 0.73
3.453AsnAsp: 3.453 ± 0.641
2.713AsnGlu: 2.713 ± 0.55
2.713AsnPhe: 2.713 ± 0.498
1.48AsnGly: 1.48 ± 0.58
0.74AsnHis: 0.74 ± 0.307
2.219AsnIle: 2.219 ± 1.093
3.699AsnLys: 3.699 ± 0.789
4.932AsnLeu: 4.932 ± 0.616
0.986AsnMet: 0.986 ± 0.603
3.206AsnAsn: 3.206 ± 1.171
1.233AsnPro: 1.233 ± 0.404
1.48AsnGln: 1.48 ± 0.899
1.973AsnArg: 1.973 ± 1.042
3.206AsnSer: 3.206 ± 0.769
3.206AsnThr: 3.206 ± 0.562
3.453AsnVal: 3.453 ± 1.944
1.233AsnTrp: 1.233 ± 0.495
1.48AsnTyr: 1.48 ± 0.855
0.0AsnXaa: 0.0 ± 0.0
Pro
0.74ProAla: 0.74 ± 0.562
0.493ProCys: 0.493 ± 0.329
3.946ProAsp: 3.946 ± 0.804
0.986ProGlu: 0.986 ± 0.374
1.233ProPhe: 1.233 ± 0.755
2.219ProGly: 2.219 ± 0.857
0.247ProHis: 0.247 ± 0.165
0.493ProIle: 0.493 ± 0.329
3.946ProLys: 3.946 ± 0.849
3.206ProLeu: 3.206 ± 0.938
1.233ProMet: 1.233 ± 0.337
0.74ProAsn: 0.74 ± 0.466
1.48ProPro: 1.48 ± 0.462
0.74ProGln: 0.74 ± 0.635
1.726ProArg: 1.726 ± 0.613
1.48ProSer: 1.48 ± 0.561
1.726ProThr: 1.726 ± 0.929
2.959ProVal: 2.959 ± 0.739
0.493ProTrp: 0.493 ± 0.187
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.219GlnAla: 2.219 ± 1.222
0.493GlnCys: 0.493 ± 0.187
0.986GlnAsp: 0.986 ± 0.415
1.233GlnGlu: 1.233 ± 0.791
1.726GlnPhe: 1.726 ± 0.62
2.713GlnGly: 2.713 ± 0.719
0.493GlnHis: 0.493 ± 0.329
2.959GlnIle: 2.959 ± 1.401
1.973GlnLys: 1.973 ± 0.547
3.946GlnLeu: 3.946 ± 0.67
0.247GlnMet: 0.247 ± 0.3
2.959GlnAsn: 2.959 ± 0.579
0.247GlnPro: 0.247 ± 0.507
1.973GlnGln: 1.973 ± 1.81
4.192GlnArg: 4.192 ± 0.82
3.206GlnSer: 3.206 ± 0.631
1.726GlnThr: 1.726 ± 0.399
1.48GlnVal: 1.48 ± 0.35
0.493GlnTrp: 0.493 ± 0.187
0.74GlnTyr: 0.74 ± 0.313
0.0GlnXaa: 0.0 ± 0.0
Arg
1.726ArgAla: 1.726 ± 0.576
2.466ArgCys: 2.466 ± 0.885
4.192ArgAsp: 4.192 ± 0.568
3.206ArgGlu: 3.206 ± 0.604
3.453ArgPhe: 3.453 ± 0.667
3.946ArgGly: 3.946 ± 0.954
1.233ArgHis: 1.233 ± 0.404
3.206ArgIle: 3.206 ± 0.599
5.425ArgLys: 5.425 ± 0.963
6.905ArgLeu: 6.905 ± 1.005
1.973ArgMet: 1.973 ± 0.389
3.699ArgAsn: 3.699 ± 0.577
2.219ArgPro: 2.219 ± 0.501
1.233ArgGln: 1.233 ± 0.352
4.192ArgArg: 4.192 ± 1.027
2.466ArgSer: 2.466 ± 0.533
0.986ArgThr: 0.986 ± 0.415
3.206ArgVal: 3.206 ± 0.865
0.74ArgTrp: 0.74 ± 0.307
1.233ArgTyr: 1.233 ± 0.393
0.0ArgXaa: 0.0 ± 0.0
Ser
3.946SerAla: 3.946 ± 2.102
2.219SerCys: 2.219 ± 0.73
6.658SerAsp: 6.658 ± 0.877
4.932SerGlu: 4.932 ± 1.219
3.699SerPhe: 3.699 ± 0.536
3.206SerGly: 3.206 ± 2.558
0.74SerHis: 0.74 ± 0.612
1.973SerIle: 1.973 ± 1.63
2.713SerLys: 2.713 ± 0.605
6.412SerLeu: 6.412 ± 1.59
1.726SerMet: 1.726 ± 0.56
1.726SerAsn: 1.726 ± 1.436
0.74SerPro: 0.74 ± 0.803
3.206SerGln: 3.206 ± 0.66
4.192SerArg: 4.192 ± 0.87
7.891SerSer: 7.891 ± 1.265
3.946SerThr: 3.946 ± 0.613
6.658SerVal: 6.658 ± 1.581
0.74SerTrp: 0.74 ± 0.276
2.959SerTyr: 2.959 ± 0.777
0.0SerXaa: 0.0 ± 0.0
Thr
3.946ThrAla: 3.946 ± 0.679
1.233ThrCys: 1.233 ± 0.651
3.946ThrAsp: 3.946 ± 0.856
2.713ThrGlu: 2.713 ± 0.457
2.959ThrPhe: 2.959 ± 0.829
3.946ThrGly: 3.946 ± 0.991
0.493ThrHis: 0.493 ± 0.187
0.986ThrIle: 0.986 ± 0.307
4.192ThrLys: 4.192 ± 1.289
4.686ThrLeu: 4.686 ± 0.791
1.48ThrMet: 1.48 ± 0.389
2.959ThrAsn: 2.959 ± 0.609
0.74ThrPro: 0.74 ± 0.485
0.986ThrGln: 0.986 ± 0.382
2.466ThrArg: 2.466 ± 0.628
3.699ThrSer: 3.699 ± 1.718
2.466ThrThr: 2.466 ± 0.419
5.425ThrVal: 5.425 ± 0.655
0.493ThrTrp: 0.493 ± 0.187
1.233ThrTyr: 1.233 ± 0.368
0.0ThrXaa: 0.0 ± 0.0
Val
6.165ValAla: 6.165 ± 1.779
0.74ValCys: 0.74 ± 0.279
7.398ValAsp: 7.398 ± 1.083
4.439ValGlu: 4.439 ± 0.861
5.425ValPhe: 5.425 ± 1.226
2.466ValGly: 2.466 ± 1.208
1.973ValHis: 1.973 ± 0.475
2.466ValIle: 2.466 ± 0.774
6.905ValLys: 6.905 ± 0.834
6.165ValLeu: 6.165 ± 0.889
0.247ValMet: 0.247 ± 0.165
4.439ValAsn: 4.439 ± 1.083
5.179ValPro: 5.179 ± 0.736
1.726ValGln: 1.726 ± 0.639
4.686ValArg: 4.686 ± 0.322
5.425ValSer: 5.425 ± 1.364
2.713ValThr: 2.713 ± 0.87
6.412ValVal: 6.412 ± 1.143
0.493ValTrp: 0.493 ± 0.676
1.726ValTyr: 1.726 ± 0.697
0.0ValXaa: 0.0 ± 0.0
Trp
0.493TrpAla: 0.493 ± 0.351
0.0TrpCys: 0.0 ± 0.0
0.247TrpAsp: 0.247 ± 0.316
1.233TrpGlu: 1.233 ± 0.368
0.493TrpPhe: 0.493 ± 0.518
0.986TrpGly: 0.986 ± 0.374
0.0TrpHis: 0.0 ± 0.0
0.986TrpIle: 0.986 ± 0.374
1.48TrpLys: 1.48 ± 0.529
0.986TrpLeu: 0.986 ± 0.374
0.0TrpMet: 0.0 ± 0.164
0.493TrpAsn: 0.493 ± 0.468
0.247TrpPro: 0.247 ± 0.38
1.233TrpGln: 1.233 ± 0.29
0.247TrpArg: 0.247 ± 0.165
0.986TrpSer: 0.986 ± 0.374
0.493TrpThr: 0.493 ± 0.187
0.986TrpVal: 0.986 ± 0.603
0.247TrpTrp: 0.247 ± 0.165
0.74TrpTyr: 0.74 ± 0.43
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.48TyrAla: 1.48 ± 0.509
0.247TyrCys: 0.247 ± 0.427
1.973TyrAsp: 1.973 ± 0.83
1.973TyrGlu: 1.973 ± 0.424
1.726TyrPhe: 1.726 ± 0.5
0.74TyrGly: 0.74 ± 0.385
0.247TyrHis: 0.247 ± 0.165
2.219TyrIle: 2.219 ± 0.53
2.219TyrLys: 2.219 ± 0.62
3.206TyrLeu: 3.206 ± 0.563
1.233TyrMet: 1.233 ± 0.368
1.726TyrAsn: 1.726 ± 0.436
1.48TyrPro: 1.48 ± 0.433
1.233TyrGln: 1.233 ± 0.622
3.699TyrArg: 3.699 ± 0.709
0.986TyrSer: 0.986 ± 0.699
0.986TyrThr: 0.986 ± 0.374
1.233TyrVal: 1.233 ± 0.354
0.0TyrTrp: 0.0 ± 0.0
1.233TyrTyr: 1.233 ± 0.337
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.247XaaArg: 0.247 ± 0.165
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski