Amino acid dipepetide frequency for European turkey coronavirus 080385d

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.326AlaAla: 5.326 ± 1.097
2.441AlaCys: 2.441 ± 0.364
3.661AlaAsp: 3.661 ± 0.783
2.108AlaGlu: 2.108 ± 0.571
2.885AlaPhe: 2.885 ± 0.627
3.439AlaGly: 3.439 ± 0.699
0.777AlaHis: 0.777 ± 0.147
5.437AlaIle: 5.437 ± 0.938
4.993AlaLys: 4.993 ± 1.454
6.213AlaLeu: 6.213 ± 0.581
1.775AlaMet: 1.775 ± 0.34
3.218AlaAsn: 3.218 ± 0.648
2.552AlaPro: 2.552 ± 0.576
2.219AlaGln: 2.219 ± 0.455
2.33AlaArg: 2.33 ± 0.541
3.218AlaSer: 3.218 ± 1.149
3.883AlaThr: 3.883 ± 0.791
4.993AlaVal: 4.993 ± 0.96
0.999AlaTrp: 0.999 ± 0.384
2.885AlaTyr: 2.885 ± 0.567
0.0AlaXaa: 0.0 ± 0.0
Cys
1.775CysAla: 1.775 ± 0.432
1.664CysCys: 1.664 ± 0.649
2.108CysAsp: 2.108 ± 0.505
1.997CysGlu: 1.997 ± 0.495
1.553CysPhe: 1.553 ± 0.346
2.885CysGly: 2.885 ± 0.492
0.777CysHis: 0.777 ± 0.158
1.775CysIle: 1.775 ± 0.423
1.775CysLys: 1.775 ± 0.674
2.219CysLeu: 2.219 ± 0.314
0.555CysMet: 0.555 ± 0.265
1.886CysAsn: 1.886 ± 0.693
0.666CysPro: 0.666 ± 0.254
0.888CysGln: 0.888 ± 0.219
1.775CysArg: 1.775 ± 0.39
1.331CysSer: 1.331 ± 0.365
1.442CysThr: 1.442 ± 0.51
3.661CysVal: 3.661 ± 0.543
0.555CysTrp: 0.555 ± 0.238
2.33CysTyr: 2.33 ± 0.717
0.0CysXaa: 0.0 ± 0.0
Asp
3.55AspAla: 3.55 ± 1.168
1.886AspCys: 1.886 ± 0.935
3.329AspAsp: 3.329 ± 0.891
3.329AspGlu: 3.329 ± 1.124
3.218AspPhe: 3.218 ± 1.203
4.438AspGly: 4.438 ± 1.012
0.555AspHis: 0.555 ± 0.406
3.55AspIle: 3.55 ± 0.625
2.663AspLys: 2.663 ± 0.534
4.771AspLeu: 4.771 ± 0.501
0.444AspMet: 0.444 ± 0.377
2.885AspAsn: 2.885 ± 0.657
2.219AspPro: 2.219 ± 0.492
1.553AspGln: 1.553 ± 0.528
1.997AspArg: 1.997 ± 0.486
3.661AspSer: 3.661 ± 0.653
3.107AspThr: 3.107 ± 0.575
4.105AspVal: 4.105 ± 0.836
0.555AspTrp: 0.555 ± 0.124
2.441AspTyr: 2.441 ± 1.038
0.111AspXaa: 0.111 ± 0.074
Glu
2.663GluAla: 2.663 ± 1.112
1.22GluCys: 1.22 ± 0.315
3.329GluAsp: 3.329 ± 0.626
3.107GluGlu: 3.107 ± 0.609
2.996GluPhe: 2.996 ± 0.695
2.441GluGly: 2.441 ± 0.771
0.888GluHis: 0.888 ± 0.203
1.664GluIle: 1.664 ± 0.337
3.883GluLys: 3.883 ± 1.184
4.438GluLeu: 4.438 ± 0.669
0.555GluMet: 0.555 ± 0.382
2.663GluAsn: 2.663 ± 0.452
2.552GluPro: 2.552 ± 0.513
2.33GluGln: 2.33 ± 0.273
1.331GluArg: 1.331 ± 0.198
2.219GluSer: 2.219 ± 0.701
2.108GluThr: 2.108 ± 0.321
3.55GluVal: 3.55 ± 0.814
0.222GluTrp: 0.222 ± 0.099
2.108GluTyr: 2.108 ± 0.492
0.0GluXaa: 0.0 ± 0.0
Phe
2.663PheAla: 2.663 ± 0.526
2.441PheCys: 2.441 ± 0.362
3.883PheAsp: 3.883 ± 0.512
3.772PheGlu: 3.772 ± 0.695
2.441PhePhe: 2.441 ± 0.551
2.663PheGly: 2.663 ± 0.518
0.444PheHis: 0.444 ± 0.325
3.439PheIle: 3.439 ± 0.399
3.772PheLys: 3.772 ± 1.217
3.107PheLeu: 3.107 ± 0.664
0.666PheMet: 0.666 ± 0.18
3.661PheAsn: 3.661 ± 0.711
0.222PhePro: 0.222 ± 0.192
1.997PheGln: 1.997 ± 0.714
1.331PheArg: 1.331 ± 0.398
3.439PheSer: 3.439 ± 0.547
3.329PheThr: 3.329 ± 1.022
7.656PheVal: 7.656 ± 1.238
1.553PheTrp: 1.553 ± 0.446
2.108PheTyr: 2.108 ± 0.346
0.0PheXaa: 0.0 ± 0.0
Gly
3.439GlyAla: 3.439 ± 0.406
1.775GlyCys: 1.775 ± 0.513
3.994GlyAsp: 3.994 ± 0.889
2.552GlyGlu: 2.552 ± 0.291
3.661GlyPhe: 3.661 ± 0.84
4.66GlyGly: 4.66 ± 0.733
1.442GlyHis: 1.442 ± 0.644
3.439GlyIle: 3.439 ± 0.738
3.883GlyLys: 3.883 ± 0.461
4.327GlyLeu: 4.327 ± 0.788
1.11GlyMet: 1.11 ± 0.277
3.883GlyAsn: 3.883 ± 0.69
1.553GlyPro: 1.553 ± 0.803
0.666GlyGln: 0.666 ± 0.514
1.775GlyArg: 1.775 ± 1.218
5.437GlySer: 5.437 ± 0.995
3.439GlyThr: 3.439 ± 0.435
7.878GlyVal: 7.878 ± 0.703
0.777GlyTrp: 0.777 ± 0.247
2.774GlyTyr: 2.774 ± 0.422
0.0GlyXaa: 0.0 ± 0.0
His
1.331HisAla: 1.331 ± 0.562
0.888HisCys: 0.888 ± 0.382
0.555HisAsp: 0.555 ± 0.11
0.888HisGlu: 0.888 ± 0.546
1.442HisPhe: 1.442 ± 0.601
1.11HisGly: 1.11 ± 0.379
0.444HisHis: 0.444 ± 0.097
0.888HisIle: 0.888 ± 0.326
1.11HisLys: 1.11 ± 0.551
1.442HisLeu: 1.442 ± 0.404
0.333HisMet: 0.333 ± 0.223
1.11HisAsn: 1.11 ± 0.289
0.888HisPro: 0.888 ± 0.191
0.444HisGln: 0.444 ± 0.235
0.333HisArg: 0.333 ± 0.432
0.777HisSer: 0.777 ± 0.355
1.22HisThr: 1.22 ± 0.44
1.553HisVal: 1.553 ± 0.449
0.222HisTrp: 0.222 ± 0.148
0.666HisTyr: 0.666 ± 0.46
0.0HisXaa: 0.0 ± 0.0
Ile
3.661IleAla: 3.661 ± 0.71
0.666IleCys: 0.666 ± 0.168
2.663IleAsp: 2.663 ± 0.707
1.775IleGlu: 1.775 ± 0.259
2.885IlePhe: 2.885 ± 0.296
2.774IleGly: 2.774 ± 0.589
0.444IleHis: 0.444 ± 0.097
2.663IleIle: 2.663 ± 0.982
2.885IleLys: 2.885 ± 1.065
6.213IleLeu: 6.213 ± 0.766
0.555IleMet: 0.555 ± 0.276
3.107IleAsn: 3.107 ± 1.249
2.663IlePro: 2.663 ± 0.287
2.219IleGln: 2.219 ± 0.9
1.553IleArg: 1.553 ± 0.384
3.772IleSer: 3.772 ± 0.646
3.329IleThr: 3.329 ± 0.459
5.769IleVal: 5.769 ± 1.4
0.444IleTrp: 0.444 ± 0.209
3.772IleTyr: 3.772 ± 1.101
0.0IleXaa: 0.0 ± 0.0
Lys
5.215LysAla: 5.215 ± 1.469
2.219LysCys: 2.219 ± 0.318
3.329LysAsp: 3.329 ± 0.759
3.218LysGlu: 3.218 ± 0.42
3.661LysPhe: 3.661 ± 1.241
3.661LysGly: 3.661 ± 0.588
1.331LysHis: 1.331 ± 0.595
2.552LysIle: 2.552 ± 0.527
3.218LysLys: 3.218 ± 1.221
4.438LysLeu: 4.438 ± 1.128
1.22LysMet: 1.22 ± 0.361
2.33LysAsn: 2.33 ± 0.598
3.55LysPro: 3.55 ± 0.712
2.108LysGln: 2.108 ± 0.481
1.997LysArg: 1.997 ± 0.659
4.438LysSer: 4.438 ± 0.358
2.996LysThr: 2.996 ± 0.622
5.437LysVal: 5.437 ± 1.064
0.999LysTrp: 0.999 ± 0.393
2.996LysTyr: 2.996 ± 0.923
0.0LysXaa: 0.0 ± 0.0
Leu
6.99LeuAla: 6.99 ± 0.844
2.33LeuCys: 2.33 ± 0.47
3.55LeuAsp: 3.55 ± 1.018
3.218LeuGlu: 3.218 ± 0.485
4.993LeuPhe: 4.993 ± 1.136
4.66LeuGly: 4.66 ± 0.443
2.108LeuHis: 2.108 ± 0.79
4.438LeuIle: 4.438 ± 0.669
5.437LeuLys: 5.437 ± 1.377
8.21LeuLeu: 8.21 ± 1.871
1.886LeuMet: 1.886 ± 0.592
4.66LeuAsn: 4.66 ± 2.271
3.661LeuPro: 3.661 ± 0.548
3.661LeuGln: 3.661 ± 0.885
3.55LeuArg: 3.55 ± 0.491
6.213LeuSer: 6.213 ± 1.411
5.215LeuThr: 5.215 ± 1.707
7.212LeuVal: 7.212 ± 1.305
0.999LeuTrp: 0.999 ± 0.592
5.104LeuTyr: 5.104 ± 0.856
0.0LeuXaa: 0.0 ± 0.0
Met
1.553MetAla: 1.553 ± 0.702
0.444MetCys: 0.444 ± 0.205
0.999MetAsp: 0.999 ± 0.294
0.444MetGlu: 0.444 ± 0.235
1.11MetPhe: 1.11 ± 0.495
0.999MetGly: 0.999 ± 0.233
0.666MetHis: 0.666 ± 0.292
0.333MetIle: 0.333 ± 0.306
0.333MetLys: 0.333 ± 0.271
2.108MetLeu: 2.108 ± 0.392
0.444MetMet: 0.444 ± 0.372
0.777MetAsn: 0.777 ± 0.366
0.999MetPro: 0.999 ± 0.457
0.555MetGln: 0.555 ± 0.11
0.666MetArg: 0.666 ± 0.292
1.442MetSer: 1.442 ± 0.346
0.999MetThr: 0.999 ± 0.463
1.331MetVal: 1.331 ± 0.49
0.0MetTrp: 0.0 ± 0.0
1.22MetTyr: 1.22 ± 0.568
0.0MetXaa: 0.0 ± 0.0
Asn
3.661AsnAla: 3.661 ± 0.4
1.886AsnCys: 1.886 ± 0.735
1.775AsnAsp: 1.775 ± 0.422
1.553AsnGlu: 1.553 ± 0.387
2.996AsnPhe: 2.996 ± 0.76
4.549AsnGly: 4.549 ± 0.839
0.666AsnHis: 0.666 ± 0.292
3.883AsnIle: 3.883 ± 0.499
2.996AsnLys: 2.996 ± 0.496
6.768AsnLeu: 6.768 ± 0.961
0.999AsnMet: 0.999 ± 0.517
3.55AsnAsn: 3.55 ± 1.052
1.664AsnPro: 1.664 ± 0.588
1.553AsnGln: 1.553 ± 0.376
1.442AsnArg: 1.442 ± 0.422
4.216AsnSer: 4.216 ± 1.77
3.329AsnThr: 3.329 ± 0.92
4.327AsnVal: 4.327 ± 1.489
0.999AsnTrp: 0.999 ± 0.427
3.107AsnTyr: 3.107 ± 0.917
0.0AsnXaa: 0.0 ± 0.0
Pro
1.886ProAla: 1.886 ± 0.738
0.555ProCys: 0.555 ± 0.251
1.553ProAsp: 1.553 ± 0.856
2.33ProGlu: 2.33 ± 0.323
1.664ProPhe: 1.664 ± 0.308
2.774ProGly: 2.774 ± 0.455
0.555ProHis: 0.555 ± 0.276
2.108ProIle: 2.108 ± 0.396
3.439ProLys: 3.439 ± 1.887
3.218ProLeu: 3.218 ± 0.386
0.333ProMet: 0.333 ± 0.208
2.552ProAsn: 2.552 ± 0.636
1.775ProPro: 1.775 ± 0.431
2.108ProGln: 2.108 ± 0.319
1.553ProArg: 1.553 ± 0.54
1.997ProSer: 1.997 ± 0.53
2.885ProThr: 2.885 ± 0.631
2.663ProVal: 2.663 ± 0.458
0.555ProTrp: 0.555 ± 0.124
1.22ProTyr: 1.22 ± 0.35
0.0ProXaa: 0.0 ± 0.0
Gln
2.219GlnAla: 2.219 ± 0.821
1.331GlnCys: 1.331 ± 0.362
1.775GlnAsp: 1.775 ± 0.557
1.886GlnGlu: 1.886 ± 0.626
1.442GlnPhe: 1.442 ± 0.266
1.997GlnGly: 1.997 ± 0.483
0.777GlnHis: 0.777 ± 0.517
1.22GlnIle: 1.22 ± 0.605
1.997GlnLys: 1.997 ± 0.282
3.661GlnLeu: 3.661 ± 0.78
0.555GlnMet: 0.555 ± 0.29
1.11GlnAsn: 1.11 ± 0.369
1.22GlnPro: 1.22 ± 0.923
1.886GlnGln: 1.886 ± 1.049
1.442GlnArg: 1.442 ± 0.419
2.996GlnSer: 2.996 ± 1.321
2.219GlnThr: 2.219 ± 0.66
2.774GlnVal: 2.774 ± 0.343
0.888GlnTrp: 0.888 ± 0.328
1.886GlnTyr: 1.886 ± 0.95
0.0GlnXaa: 0.0 ± 0.0
Arg
2.774ArgAla: 2.774 ± 0.737
1.22ArgCys: 1.22 ± 0.451
1.997ArgAsp: 1.997 ± 0.439
1.664ArgGlu: 1.664 ± 0.455
1.553ArgPhe: 1.553 ± 0.509
2.885ArgGly: 2.885 ± 1.03
0.555ArgHis: 0.555 ± 0.248
1.775ArgIle: 1.775 ± 0.343
1.886ArgLys: 1.886 ± 0.523
2.663ArgLeu: 2.663 ± 0.786
0.333ArgMet: 0.333 ± 0.239
2.774ArgAsn: 2.774 ± 0.9
1.22ArgPro: 1.22 ± 0.763
1.664ArgGln: 1.664 ± 0.606
1.664ArgArg: 1.664 ± 0.792
2.774ArgSer: 2.774 ± 1.432
1.775ArgThr: 1.775 ± 0.978
2.33ArgVal: 2.33 ± 0.636
0.111ArgTrp: 0.111 ± 0.222
1.886ArgTyr: 1.886 ± 0.548
0.0ArgXaa: 0.0 ± 0.0
Ser
4.549SerAla: 4.549 ± 0.333
2.33SerCys: 2.33 ± 0.875
3.994SerAsp: 3.994 ± 0.624
2.33SerGlu: 2.33 ± 0.893
4.993SerPhe: 4.993 ± 0.706
4.327SerGly: 4.327 ± 0.882
1.553SerHis: 1.553 ± 0.344
4.549SerIle: 4.549 ± 0.782
3.883SerLys: 3.883 ± 0.464
5.104SerLeu: 5.104 ± 1.172
0.666SerMet: 0.666 ± 0.114
3.994SerAsn: 3.994 ± 1.09
1.442SerPro: 1.442 ± 0.414
2.33SerGln: 2.33 ± 0.26
2.663SerArg: 2.663 ± 1.448
5.104SerSer: 5.104 ± 2.169
4.327SerThr: 4.327 ± 1.381
5.991SerVal: 5.991 ± 1.399
0.666SerTrp: 0.666 ± 0.348
2.885SerTyr: 2.885 ± 0.547
0.0SerXaa: 0.0 ± 0.0
Thr
4.105ThrAla: 4.105 ± 0.665
2.108ThrCys: 2.108 ± 0.803
1.886ThrAsp: 1.886 ± 0.218
2.885ThrGlu: 2.885 ± 0.406
2.885ThrPhe: 2.885 ± 0.362
3.883ThrGly: 3.883 ± 1.596
0.777ThrHis: 0.777 ± 0.337
2.774ThrIle: 2.774 ± 0.414
2.441ThrLys: 2.441 ± 0.52
5.548ThrLeu: 5.548 ± 1.19
1.553ThrMet: 1.553 ± 0.696
3.439ThrAsn: 3.439 ± 0.65
2.774ThrPro: 2.774 ± 0.525
2.885ThrGln: 2.885 ± 0.947
2.441ThrArg: 2.441 ± 0.526
5.104ThrSer: 5.104 ± 0.865
3.661ThrThr: 3.661 ± 0.593
5.548ThrVal: 5.548 ± 1.013
0.777ThrTrp: 0.777 ± 0.39
2.108ThrTyr: 2.108 ± 0.859
0.0ThrXaa: 0.0 ± 0.0
Val
4.882ValAla: 4.882 ± 0.848
3.55ValCys: 3.55 ± 0.858
5.548ValAsp: 5.548 ± 0.996
4.993ValGlu: 4.993 ± 0.702
4.66ValPhe: 4.66 ± 1.285
4.66ValGly: 4.66 ± 0.935
1.664ValHis: 1.664 ± 0.556
4.993ValIle: 4.993 ± 0.764
5.88ValLys: 5.88 ± 1.261
8.432ValLeu: 8.432 ± 1.629
1.997ValMet: 1.997 ± 0.695
4.66ValAsn: 4.66 ± 1.256
3.883ValPro: 3.883 ± 1.269
2.774ValGln: 2.774 ± 0.472
2.441ValArg: 2.441 ± 0.515
6.324ValSer: 6.324 ± 1.08
5.548ValThr: 5.548 ± 0.933
10.318ValVal: 10.318 ± 1.835
1.11ValTrp: 1.11 ± 0.461
3.329ValTyr: 3.329 ± 0.538
0.0ValXaa: 0.0 ± 0.0
Trp
0.222TrpAla: 0.222 ± 0.148
0.555TrpCys: 0.555 ± 0.264
0.777TrpAsp: 0.777 ± 0.423
0.666TrpGlu: 0.666 ± 0.249
0.999TrpPhe: 0.999 ± 0.384
0.666TrpGly: 0.666 ± 0.404
0.333TrpHis: 0.333 ± 0.181
0.444TrpIle: 0.444 ± 0.284
0.777TrpLys: 0.777 ± 0.28
1.775TrpLeu: 1.775 ± 0.672
0.222TrpMet: 0.222 ± 0.148
0.666TrpAsn: 0.666 ± 0.244
0.333TrpPro: 0.333 ± 0.261
0.111TrpGln: 0.111 ± 0.202
0.666TrpArg: 0.666 ± 0.304
0.999TrpSer: 0.999 ± 0.357
0.333TrpThr: 0.333 ± 0.261
1.331TrpVal: 1.331 ± 0.239
0.333TrpTrp: 0.333 ± 0.174
1.11TrpTyr: 1.11 ± 0.525
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.885TyrAla: 2.885 ± 0.633
2.108TyrCys: 2.108 ± 0.908
3.661TyrAsp: 3.661 ± 1.38
1.553TyrGlu: 1.553 ± 0.682
2.552TyrPhe: 2.552 ± 0.536
2.996TyrGly: 2.996 ± 0.806
0.888TyrHis: 0.888 ± 0.546
1.886TyrIle: 1.886 ± 0.521
3.661TyrLys: 3.661 ± 0.362
3.439TyrLeu: 3.439 ± 0.386
1.11TyrMet: 1.11 ± 0.556
2.996TyrAsn: 2.996 ± 0.807
1.886TyrPro: 1.886 ± 0.628
1.331TyrGln: 1.331 ± 0.981
2.552TyrArg: 2.552 ± 0.813
2.219TyrSer: 2.219 ± 0.467
4.438TyrThr: 4.438 ± 1.192
3.218TyrVal: 3.218 ± 0.505
0.555TyrTrp: 0.555 ± 0.415
2.774TyrTyr: 2.774 ± 0.717
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.111XaaAsp: 0.111 ± 0.074
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (9014 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski