Amino acid dipepetide frequency for Beijerinckia sp. 28-YEA-48

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.261AlaAla: 16.261 ± 0.136
1.111AlaCys: 1.111 ± 0.027
6.352AlaAsp: 6.352 ± 0.059
6.366AlaGlu: 6.366 ± 0.066
4.647AlaPhe: 4.647 ± 0.047
10.368AlaGly: 10.368 ± 0.102
2.265AlaHis: 2.265 ± 0.037
6.855AlaIle: 6.855 ± 0.063
4.416AlaLys: 4.416 ± 0.057
13.086AlaLeu: 13.086 ± 0.107
3.494AlaMet: 3.494 ± 0.048
3.275AlaAsn: 3.275 ± 0.052
5.79AlaPro: 5.79 ± 0.065
4.614AlaGln: 4.614 ± 0.055
8.219AlaArg: 8.219 ± 0.074
6.665AlaSer: 6.665 ± 0.072
6.486AlaThr: 6.486 ± 0.079
8.307AlaVal: 8.307 ± 0.072
1.527AlaTrp: 1.527 ± 0.033
2.629AlaTyr: 2.629 ± 0.037
0.0AlaXaa: 0.0 ± 0.0
Cys
1.025CysAla: 1.025 ± 0.022
0.119CysCys: 0.119 ± 0.008
0.508CysAsp: 0.508 ± 0.018
0.375CysGlu: 0.375 ± 0.016
0.328CysPhe: 0.328 ± 0.015
0.932CysGly: 0.932 ± 0.028
0.234CysHis: 0.234 ± 0.011
0.433CysIle: 0.433 ± 0.015
0.212CysLys: 0.212 ± 0.01
0.794CysLeu: 0.794 ± 0.023
0.169CysMet: 0.169 ± 0.01
0.217CysAsn: 0.217 ± 0.012
0.409CysPro: 0.409 ± 0.017
0.22CysGln: 0.22 ± 0.012
0.569CysArg: 0.569 ± 0.02
0.435CysSer: 0.435 ± 0.015
0.431CysThr: 0.431 ± 0.018
0.64CysVal: 0.64 ± 0.019
0.113CysTrp: 0.113 ± 0.007
0.211CysTyr: 0.211 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
6.179AspAla: 6.179 ± 0.061
0.44AspCys: 0.44 ± 0.016
2.822AspAsp: 2.822 ± 0.048
3.001AspGlu: 3.001 ± 0.047
2.244AspPhe: 2.244 ± 0.033
4.724AspGly: 4.724 ± 0.053
1.268AspHis: 1.268 ± 0.026
3.231AspIle: 3.231 ± 0.039
1.93AspLys: 1.93 ± 0.035
5.72AspLeu: 5.72 ± 0.053
1.418AspMet: 1.418 ± 0.031
1.394AspAsn: 1.394 ± 0.026
3.263AspPro: 3.263 ± 0.048
1.707AspGln: 1.707 ± 0.029
3.842AspArg: 3.842 ± 0.045
2.095AspSer: 2.095 ± 0.036
2.466AspThr: 2.466 ± 0.037
4.226AspVal: 4.226 ± 0.047
0.89AspTrp: 0.89 ± 0.02
1.474AspTyr: 1.474 ± 0.029
0.0AspXaa: 0.0 ± 0.0
Glu
6.764GluAla: 6.764 ± 0.076
0.335GluCys: 0.335 ± 0.015
2.279GluAsp: 2.279 ± 0.04
2.578GluGlu: 2.578 ± 0.043
1.727GluPhe: 1.727 ± 0.031
3.556GluGly: 3.556 ± 0.046
1.103GluHis: 1.103 ± 0.027
3.238GluIle: 3.238 ± 0.044
2.299GluLys: 2.299 ± 0.042
4.721GluLeu: 4.721 ± 0.054
1.404GluMet: 1.404 ± 0.028
1.58GluAsn: 1.58 ± 0.031
2.452GluPro: 2.452 ± 0.04
2.004GluGln: 2.004 ± 0.031
4.459GluArg: 4.459 ± 0.058
2.174GluSer: 2.174 ± 0.033
3.205GluThr: 3.205 ± 0.04
3.351GluVal: 3.351 ± 0.051
0.637GluTrp: 0.637 ± 0.019
0.996GluTyr: 0.996 ± 0.023
0.0GluXaa: 0.0 ± 0.0
Phe
4.863PheAla: 4.863 ± 0.058
0.408PheCys: 0.408 ± 0.016
2.726PheAsp: 2.726 ± 0.037
2.046PheGlu: 2.046 ± 0.038
1.53PhePhe: 1.53 ± 0.034
3.848PheGly: 3.848 ± 0.05
0.787PheHis: 0.787 ± 0.021
1.918PheIle: 1.918 ± 0.035
1.185PheLys: 1.185 ± 0.031
3.472PheLeu: 3.472 ± 0.054
0.899PheMet: 0.899 ± 0.024
1.264PheAsn: 1.264 ± 0.032
1.726PhePro: 1.726 ± 0.032
1.08PheGln: 1.08 ± 0.022
2.163PheArg: 2.163 ± 0.034
2.415PheSer: 2.415 ± 0.04
2.072PheThr: 2.072 ± 0.032
3.019PheVal: 3.019 ± 0.048
0.556PheTrp: 0.556 ± 0.017
0.948PheTyr: 0.948 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
9.36GlyAla: 9.36 ± 0.094
0.772GlyCys: 0.772 ± 0.021
4.046GlyAsp: 4.046 ± 0.053
4.128GlyGlu: 4.128 ± 0.057
3.757GlyPhe: 3.757 ± 0.044
7.591GlyGly: 7.591 ± 0.161
1.868GlyHis: 1.868 ± 0.03
4.766GlyIle: 4.766 ± 0.059
3.324GlyLys: 3.324 ± 0.046
8.794GlyLeu: 8.794 ± 0.068
2.178GlyMet: 2.178 ± 0.034
2.39GlyAsn: 2.39 ± 0.063
3.622GlyPro: 3.622 ± 0.049
2.965GlyGln: 2.965 ± 0.043
5.603GlyArg: 5.603 ± 0.056
4.888GlySer: 4.888 ± 0.088
4.83GlyThr: 4.83 ± 0.101
6.136GlyVal: 6.136 ± 0.061
1.356GlyTrp: 1.356 ± 0.027
2.389GlyTyr: 2.389 ± 0.042
0.0GlyXaa: 0.0 ± 0.0
His
2.223HisAla: 2.223 ± 0.036
0.215HisCys: 0.215 ± 0.01
1.188HisAsp: 1.188 ± 0.029
0.958HisGlu: 0.958 ± 0.024
0.904HisPhe: 0.904 ± 0.022
1.892HisGly: 1.892 ± 0.033
0.573HisHis: 0.573 ± 0.022
1.065HisIle: 1.065 ± 0.025
0.529HisLys: 0.529 ± 0.018
2.08HisLeu: 2.08 ± 0.033
0.543HisMet: 0.543 ± 0.019
0.511HisAsn: 0.511 ± 0.018
1.32HisPro: 1.32 ± 0.026
0.598HisGln: 0.598 ± 0.016
1.36HisArg: 1.36 ± 0.029
0.931HisSer: 0.931 ± 0.02
0.877HisThr: 0.877 ± 0.024
1.562HisVal: 1.562 ± 0.028
0.345HisTrp: 0.345 ± 0.015
0.587HisTyr: 0.587 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
7.96IleAla: 7.96 ± 0.082
0.556IleCys: 0.556 ± 0.018
3.851IleAsp: 3.851 ± 0.05
3.59IleGlu: 3.59 ± 0.052
1.891IlePhe: 1.891 ± 0.032
5.521IleGly: 5.521 ± 0.058
0.93IleHis: 0.93 ± 0.021
2.642IleIle: 2.642 ± 0.041
1.711IleLys: 1.711 ± 0.03
4.62IleLeu: 4.62 ± 0.058
1.053IleMet: 1.053 ± 0.022
1.729IleAsn: 1.729 ± 0.045
2.381IlePro: 2.381 ± 0.035
1.278IleGln: 1.278 ± 0.025
3.038IleArg: 3.038 ± 0.039
3.179IleSer: 3.179 ± 0.048
2.916IleThr: 2.916 ± 0.06
4.912IleVal: 4.912 ± 0.052
0.663IleTrp: 0.663 ± 0.021
1.322IleTyr: 1.322 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
4.352LysAla: 4.352 ± 0.056
0.155LysCys: 0.155 ± 0.009
1.84LysAsp: 1.84 ± 0.037
1.605LysGlu: 1.605 ± 0.033
1.071LysPhe: 1.071 ± 0.025
2.617LysGly: 2.617 ± 0.042
0.664LysHis: 0.664 ± 0.019
2.113LysIle: 2.113 ± 0.041
1.379LysLys: 1.379 ± 0.034
3.648LysLeu: 3.648 ± 0.053
0.905LysMet: 0.905 ± 0.023
0.997LysAsn: 0.997 ± 0.024
2.317LysPro: 2.317 ± 0.039
1.176LysGln: 1.176 ± 0.026
2.378LysArg: 2.378 ± 0.042
2.056LysSer: 2.056 ± 0.035
2.147LysThr: 2.147 ± 0.032
2.63LysVal: 2.63 ± 0.046
0.431LysTrp: 0.431 ± 0.016
0.659LysTyr: 0.659 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
13.231LeuAla: 13.231 ± 0.099
0.867LeuCys: 0.867 ± 0.021
5.528LeuAsp: 5.528 ± 0.063
4.726LeuGlu: 4.726 ± 0.055
3.718LeuPhe: 3.718 ± 0.056
7.989LeuGly: 7.989 ± 0.073
1.841LeuHis: 1.841 ± 0.037
5.361LeuIle: 5.361 ± 0.068
3.554LeuLys: 3.554 ± 0.054
9.311LeuLeu: 9.311 ± 0.096
2.341LeuMet: 2.341 ± 0.039
2.856LeuAsn: 2.856 ± 0.043
5.622LeuPro: 5.622 ± 0.066
2.941LeuGln: 2.941 ± 0.036
6.74LeuArg: 6.74 ± 0.069
6.478LeuSer: 6.478 ± 0.059
5.633LeuThr: 5.633 ± 0.065
7.337LeuVal: 7.337 ± 0.072
1.115LeuTrp: 1.115 ± 0.028
2.055LeuTyr: 2.055 ± 0.039
0.0LeuXaa: 0.0 ± 0.0
Met
3.047MetAla: 3.047 ± 0.044
0.172MetCys: 0.172 ± 0.009
1.106MetAsp: 1.106 ± 0.025
1.019MetGlu: 1.019 ± 0.024
0.836MetPhe: 0.836 ± 0.02
1.79MetGly: 1.79 ± 0.034
0.466MetHis: 0.466 ± 0.014
1.477MetIle: 1.477 ± 0.029
1.056MetLys: 1.056 ± 0.022
2.44MetLeu: 2.44 ± 0.039
0.696MetMet: 0.696 ± 0.021
0.837MetAsn: 0.837 ± 0.021
1.575MetPro: 1.575 ± 0.032
0.943MetGln: 0.943 ± 0.022
1.912MetArg: 1.912 ± 0.034
1.781MetSer: 1.781 ± 0.031
1.851MetThr: 1.851 ± 0.028
1.639MetVal: 1.639 ± 0.026
0.241MetTrp: 0.241 ± 0.011
0.357MetTyr: 0.357 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
3.454AsnAla: 3.454 ± 0.068
0.235AsnCys: 0.235 ± 0.01
1.516AsnAsp: 1.516 ± 0.031
1.322AsnGlu: 1.322 ± 0.024
1.093AsnPhe: 1.093 ± 0.026
2.843AsnGly: 2.843 ± 0.055
0.534AsnHis: 0.534 ± 0.018
1.654AsnIle: 1.654 ± 0.035
0.826AsnLys: 0.826 ± 0.023
2.693AsnLeu: 2.693 ± 0.039
0.703AsnMet: 0.703 ± 0.021
0.883AsnAsn: 0.883 ± 0.052
1.847AsnPro: 1.847 ± 0.036
0.836AsnGln: 0.836 ± 0.025
1.819AsnArg: 1.819 ± 0.034
1.494AsnSer: 1.494 ± 0.055
1.48AsnThr: 1.48 ± 0.043
2.282AsnVal: 2.282 ± 0.039
0.48AsnTrp: 0.48 ± 0.017
0.809AsnTyr: 0.809 ± 0.028
0.0AsnXaa: 0.0 ± 0.0
Pro
6.113ProAla: 6.113 ± 0.059
0.286ProCys: 0.286 ± 0.012
3.312ProAsp: 3.312 ± 0.045
3.12ProGlu: 3.12 ± 0.045
2.064ProPhe: 2.064 ± 0.031
4.493ProGly: 4.493 ± 0.054
1.121ProHis: 1.121 ± 0.028
2.695ProIle: 2.695 ± 0.039
1.9ProLys: 1.9 ± 0.033
4.909ProLeu: 4.909 ± 0.053
1.286ProMet: 1.286 ± 0.031
1.597ProAsn: 1.597 ± 0.032
2.681ProPro: 2.681 ± 0.055
2.056ProGln: 2.056 ± 0.036
3.033ProArg: 3.033 ± 0.044
3.054ProSer: 3.054 ± 0.043
2.81ProThr: 2.81 ± 0.036
4.159ProVal: 4.159 ± 0.046
0.705ProTrp: 0.705 ± 0.022
1.307ProTyr: 1.307 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
4.407GlnAla: 4.407 ± 0.061
0.221GlnCys: 0.221 ± 0.012
1.553GlnAsp: 1.553 ± 0.03
1.505GlnGlu: 1.505 ± 0.028
1.197GlnPhe: 1.197 ± 0.019
2.427GlnGly: 2.427 ± 0.035
0.643GlnHis: 0.643 ± 0.019
2.035GlnIle: 2.035 ± 0.037
1.231GlnLys: 1.231 ± 0.029
3.05GlnLeu: 3.05 ± 0.045
0.949GlnMet: 0.949 ± 0.024
1.001GlnAsn: 1.001 ± 0.024
1.856GlnPro: 1.856 ± 0.033
1.475GlnGln: 1.475 ± 0.059
2.63GlnArg: 2.63 ± 0.044
1.987GlnSer: 1.987 ± 0.034
1.938GlnThr: 1.938 ± 0.036
2.357GlnVal: 2.357 ± 0.032
0.433GlnTrp: 0.433 ± 0.015
0.64GlnTyr: 0.64 ± 0.019
0.0GlnXaa: 0.0 ± 0.0
Arg
7.5ArgAla: 7.5 ± 0.075
0.559ArgCys: 0.559 ± 0.019
3.89ArgAsp: 3.89 ± 0.045
3.645ArgGlu: 3.645 ± 0.053
2.878ArgPhe: 2.878 ± 0.04
4.66ArgGly: 4.66 ± 0.054
1.532ArgHis: 1.532 ± 0.029
3.955ArgIle: 3.955 ± 0.054
2.427ArgLys: 2.427 ± 0.039
7.35ArgLeu: 7.35 ± 0.077
1.801ArgMet: 1.801 ± 0.033
1.931ArgAsn: 1.931 ± 0.031
3.522ArgPro: 3.522 ± 0.053
2.608ArgGln: 2.608 ± 0.043
5.08ArgArg: 5.08 ± 0.073
3.663ArgSer: 3.663 ± 0.051
3.387ArgThr: 3.387 ± 0.045
4.425ArgVal: 4.425 ± 0.056
0.967ArgTrp: 0.967 ± 0.024
1.707ArgTyr: 1.707 ± 0.031
0.0ArgXaa: 0.0 ± 0.0
Ser
6.495SerAla: 6.495 ± 0.076
0.437SerCys: 0.437 ± 0.016
2.991SerAsp: 2.991 ± 0.04
2.647SerGlu: 2.647 ± 0.038
2.481SerPhe: 2.481 ± 0.038
5.665SerGly: 5.665 ± 0.096
1.118SerHis: 1.118 ± 0.029
3.128SerIle: 3.128 ± 0.053
1.77SerLys: 1.77 ± 0.033
5.617SerLeu: 5.617 ± 0.061
1.378SerMet: 1.378 ± 0.027
1.652SerAsn: 1.652 ± 0.04
2.942SerPro: 2.942 ± 0.038
1.845SerGln: 1.845 ± 0.034
3.506SerArg: 3.506 ± 0.046
3.359SerSer: 3.359 ± 0.06
3.084SerThr: 3.084 ± 0.073
4.029SerVal: 4.029 ± 0.048
0.776SerTrp: 0.776 ± 0.023
1.438SerTyr: 1.438 ± 0.031
0.0SerXaa: 0.0 ± 0.0
Thr
6.363ThrAla: 6.363 ± 0.085
0.469ThrCys: 0.469 ± 0.018
2.701ThrAsp: 2.701 ± 0.041
2.307ThrGlu: 2.307 ± 0.035
2.323ThrPhe: 2.323 ± 0.044
5.068ThrGly: 5.068 ± 0.096
1.058ThrHis: 1.058 ± 0.023
3.338ThrIle: 3.338 ± 0.06
1.725ThrLys: 1.725 ± 0.031
5.87ThrLeu: 5.87 ± 0.058
1.299ThrMet: 1.299 ± 0.028
1.524ThrAsn: 1.524 ± 0.059
3.496ThrPro: 3.496 ± 0.039
1.733ThrGln: 1.733 ± 0.028
3.336ThrArg: 3.336 ± 0.042
3.206ThrSer: 3.206 ± 0.06
3.171ThrThr: 3.171 ± 0.055
4.275ThrVal: 4.275 ± 0.06
0.696ThrTrp: 0.696 ± 0.019
1.258ThrTyr: 1.258 ± 0.03
0.0ThrXaa: 0.0 ± 0.0
Val
9.316ValAla: 9.316 ± 0.083
0.657ValCys: 0.657 ± 0.018
4.092ValAsp: 4.092 ± 0.043
4.211ValGlu: 4.211 ± 0.049
2.676ValPhe: 2.676 ± 0.038
5.59ValGly: 5.59 ± 0.062
1.414ValHis: 1.414 ± 0.026
4.091ValIle: 4.091 ± 0.046
2.481ValLys: 2.481 ± 0.041
7.2ValLeu: 7.2 ± 0.076
1.869ValMet: 1.869 ± 0.032
2.054ValAsn: 2.054 ± 0.043
3.941ValPro: 3.941 ± 0.05
2.191ValGln: 2.191 ± 0.039
4.875ValArg: 4.875 ± 0.057
4.42ValSer: 4.42 ± 0.046
4.453ValThr: 4.453 ± 0.057
5.87ValVal: 5.87 ± 0.062
0.86ValTrp: 0.86 ± 0.021
1.472ValTyr: 1.472 ± 0.028
0.0ValXaa: 0.0 ± 0.0
Trp
1.235TrpAla: 1.235 ± 0.023
0.131TrpCys: 0.131 ± 0.009
0.574TrpAsp: 0.574 ± 0.017
0.512TrpGlu: 0.512 ± 0.017
0.564TrpPhe: 0.564 ± 0.016
0.93TrpGly: 0.93 ± 0.023
0.354TrpHis: 0.354 ± 0.014
0.758TrpIle: 0.758 ± 0.025
0.489TrpLys: 0.489 ± 0.017
1.609TrpLeu: 1.609 ± 0.035
0.361TrpMet: 0.361 ± 0.015
0.449TrpAsn: 0.449 ± 0.015
0.708TrpPro: 0.708 ± 0.021
0.566TrpGln: 0.566 ± 0.015
1.141TrpArg: 1.141 ± 0.025
0.884TrpSer: 0.884 ± 0.025
0.776TrpThr: 0.776 ± 0.02
0.801TrpVal: 0.801 ± 0.022
0.205TrpTrp: 0.205 ± 0.011
0.326TrpTyr: 0.326 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.583TyrAla: 2.583 ± 0.041
0.228TyrCys: 0.228 ± 0.013
1.459TyrAsp: 1.459 ± 0.024
1.202TyrGlu: 1.202 ± 0.026
0.993TyrPhe: 0.993 ± 0.024
2.259TyrGly: 2.259 ± 0.043
0.488TyrHis: 0.488 ± 0.015
0.992TyrIle: 0.992 ± 0.022
0.698TyrLys: 0.698 ± 0.019
2.261TyrLeu: 2.261 ± 0.034
0.494TyrMet: 0.494 ± 0.017
0.661TyrAsn: 0.661 ± 0.022
1.233TyrPro: 1.233 ± 0.027
0.697TyrGln: 0.697 ± 0.018
1.784TyrArg: 1.784 ± 0.035
1.196TyrSer: 1.196 ± 0.026
1.204TyrThr: 1.204 ± 0.034
1.774TyrVal: 1.774 ± 0.031
0.378TyrTrp: 0.378 ± 0.016
0.582TyrTyr: 0.582 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5975 proteins (1913401 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski