Amino acid dipepetide frequency for Acartia tonsa copepod circovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.859AlaAla: 7.859 ± 5.001
0.0AlaCys: 0.0 ± 0.0
1.965AlaAsp: 1.965 ± 0.888
1.965AlaGlu: 1.965 ± 0.888
1.965AlaPhe: 1.965 ± 1.963
1.965AlaGly: 1.965 ± 1.963
1.965AlaHis: 1.965 ± 0.888
3.929AlaIle: 3.929 ± 1.075
3.929AlaLys: 3.929 ± 1.775
5.894AlaLeu: 5.894 ± 5.889
0.0AlaMet: 0.0 ± 0.0
1.965AlaAsn: 1.965 ± 0.888
1.965AlaPro: 1.965 ± 0.888
0.0AlaGln: 0.0 ± 0.0
7.859AlaArg: 7.859 ± 5.001
3.929AlaSer: 3.929 ± 1.075
5.894AlaThr: 5.894 ± 3.038
9.823AlaVal: 9.823 ± 1.263
0.0AlaTrp: 0.0 ± 0.0
5.894AlaTyr: 5.894 ± 3.038
0.0AlaXaa: 0.0 ± 0.0
Cys
1.965CysAla: 1.965 ± 0.888
0.0CysCys: 0.0 ± 0.0
3.929CysAsp: 3.929 ± 1.775
0.0CysGlu: 0.0 ± 0.0
1.965CysPhe: 1.965 ± 0.888
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.965CysIle: 1.965 ± 1.963
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.965CysPro: 1.965 ± 0.888
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.965CysSer: 1.965 ± 0.888
1.965CysThr: 1.965 ± 0.888
0.0CysVal: 0.0 ± 0.0
1.965CysTrp: 1.965 ± 1.963
1.965CysTyr: 1.965 ± 0.888
0.0CysXaa: 0.0 ± 0.0
Asp
1.965AspAla: 1.965 ± 0.888
0.0AspCys: 0.0 ± 0.0
1.965AspAsp: 1.965 ± 0.888
1.965AspGlu: 1.965 ± 0.888
0.0AspPhe: 0.0 ± 0.0
3.929AspGly: 3.929 ± 1.075
0.0AspHis: 0.0 ± 0.0
1.965AspIle: 1.965 ± 0.888
0.0AspLys: 0.0 ± 0.0
3.929AspLeu: 3.929 ± 1.775
0.0AspMet: 0.0 ± 0.0
3.929AspAsn: 3.929 ± 1.775
0.0AspPro: 0.0 ± 0.0
1.965AspGln: 1.965 ± 0.888
3.929AspArg: 3.929 ± 1.775
0.0AspSer: 0.0 ± 0.0
3.929AspThr: 3.929 ± 1.775
1.965AspVal: 1.965 ± 0.888
0.0AspTrp: 0.0 ± 0.0
5.894AspTyr: 5.894 ± 2.663
0.0AspXaa: 0.0 ± 0.0
Glu
1.965GluAla: 1.965 ± 0.888
3.929GluCys: 3.929 ± 1.775
1.965GluAsp: 1.965 ± 0.888
1.965GluGlu: 1.965 ± 0.888
1.965GluPhe: 1.965 ± 0.888
1.965GluGly: 1.965 ± 0.888
1.965GluHis: 1.965 ± 0.888
1.965GluIle: 1.965 ± 0.888
0.0GluLys: 0.0 ± 0.0
3.929GluLeu: 3.929 ± 1.775
5.894GluMet: 5.894 ± 2.386
0.0GluAsn: 0.0 ± 0.0
7.859GluPro: 7.859 ± 0.7
0.0GluGln: 0.0 ± 0.0
5.894GluArg: 5.894 ± 0.188
1.965GluSer: 1.965 ± 0.888
0.0GluThr: 0.0 ± 0.0
0.0GluVal: 0.0 ± 0.0
3.929GluTrp: 3.929 ± 1.775
3.929GluTyr: 3.929 ± 1.075
0.0GluXaa: 0.0 ± 0.0
Phe
1.965PheAla: 1.965 ± 0.888
1.965PheCys: 1.965 ± 0.888
3.929PheAsp: 3.929 ± 1.775
1.965PheGlu: 1.965 ± 0.888
0.0PhePhe: 0.0 ± 0.0
1.965PheGly: 1.965 ± 0.888
1.965PheHis: 1.965 ± 0.888
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
1.965PheLeu: 1.965 ± 1.963
0.0PheMet: 0.0 ± 0.0
3.929PheAsn: 3.929 ± 1.075
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
7.859PheSer: 7.859 ± 3.551
1.965PheThr: 1.965 ± 0.888
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.894GlyAla: 5.894 ± 5.889
0.0GlyCys: 0.0 ± 0.0
3.929GlyAsp: 3.929 ± 1.775
3.929GlyGlu: 3.929 ± 1.775
1.965GlyPhe: 1.965 ± 0.888
5.894GlyGly: 5.894 ± 0.188
1.965GlyHis: 1.965 ± 0.888
1.965GlyIle: 1.965 ± 0.888
5.894GlyLys: 5.894 ± 0.188
3.929GlyLeu: 3.929 ± 1.075
1.965GlyMet: 1.965 ± 0.888
0.0GlyAsn: 0.0 ± 0.0
1.965GlyPro: 1.965 ± 0.888
5.894GlyGln: 5.894 ± 2.663
1.965GlyArg: 1.965 ± 1.963
9.823GlySer: 9.823 ± 1.588
3.929GlyThr: 3.929 ± 1.775
3.929GlyVal: 3.929 ± 1.075
1.965GlyTrp: 1.965 ± 0.888
3.929GlyTyr: 3.929 ± 1.775
0.0GlyXaa: 0.0 ± 0.0
His
1.965HisAla: 1.965 ± 0.888
1.965HisCys: 1.965 ± 0.888
0.0HisAsp: 0.0 ± 0.0
1.965HisGlu: 1.965 ± 0.888
1.965HisPhe: 1.965 ± 1.963
1.965HisGly: 1.965 ± 1.963
1.965HisHis: 1.965 ± 0.888
3.929HisIle: 3.929 ± 1.775
3.929HisLys: 3.929 ± 1.075
0.0HisLeu: 0.0 ± 0.0
1.965HisMet: 1.965 ± 1.963
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.965HisGln: 1.965 ± 0.888
5.894HisArg: 5.894 ± 2.663
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
3.929HisVal: 3.929 ± 1.775
1.965HisTrp: 1.965 ± 0.888
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.929IleAla: 3.929 ± 1.075
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
3.929IleGlu: 3.929 ± 1.775
1.965IlePhe: 1.965 ± 0.888
1.965IleGly: 1.965 ± 0.888
1.965IleHis: 1.965 ± 0.888
0.0IleIle: 0.0 ± 0.0
3.929IleLys: 3.929 ± 1.775
5.894IleLeu: 5.894 ± 3.038
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
3.929IlePro: 3.929 ± 1.775
3.929IleGln: 3.929 ± 1.075
3.929IleArg: 3.929 ± 1.075
5.894IleSer: 5.894 ± 2.663
1.965IleThr: 1.965 ± 0.888
1.965IleVal: 1.965 ± 0.888
0.0IleTrp: 0.0 ± 0.0
1.965IleTyr: 1.965 ± 0.888
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.965LysGlu: 1.965 ± 0.888
0.0LysPhe: 0.0 ± 0.0
5.894LysGly: 5.894 ± 0.188
0.0LysHis: 0.0 ± 0.0
1.965LysIle: 1.965 ± 0.888
3.929LysLys: 3.929 ± 1.075
1.965LysLeu: 1.965 ± 0.888
1.965LysMet: 1.965 ± 0.784
1.965LysAsn: 1.965 ± 1.963
3.929LysPro: 3.929 ± 1.775
1.965LysGln: 1.965 ± 0.888
9.823LysArg: 9.823 ± 1.263
7.859LysSer: 7.859 ± 0.7
0.0LysThr: 0.0 ± 0.0
0.0LysVal: 0.0 ± 0.0
1.965LysTrp: 1.965 ± 0.888
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
1.965LeuAla: 1.965 ± 0.888
0.0LeuCys: 0.0 ± 0.0
7.859LeuAsp: 7.859 ± 3.551
3.929LeuGlu: 3.929 ± 1.075
1.965LeuPhe: 1.965 ± 0.888
0.0LeuGly: 0.0 ± 0.0
3.929LeuHis: 3.929 ± 1.775
5.894LeuIle: 5.894 ± 0.188
0.0LeuLys: 0.0 ± 0.0
11.788LeuLeu: 11.788 ± 3.226
1.965LeuMet: 1.965 ± 0.888
3.929LeuAsn: 3.929 ± 1.075
7.859LeuPro: 7.859 ± 0.7
0.0LeuGln: 0.0 ± 0.0
9.823LeuArg: 9.823 ± 1.263
3.929LeuSer: 3.929 ± 3.926
5.894LeuThr: 5.894 ± 0.188
3.929LeuVal: 3.929 ± 1.075
3.929LeuTrp: 3.929 ± 1.775
1.965LeuTyr: 1.965 ± 1.963
0.0LeuXaa: 0.0 ± 0.0
Met
1.965MetAla: 1.965 ± 1.963
0.0MetCys: 0.0 ± 0.0
1.965MetAsp: 1.965 ± 1.963
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
1.965MetHis: 1.965 ± 1.963
3.929MetIle: 3.929 ± 1.075
5.894MetLys: 5.894 ± 2.663
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.929MetPro: 3.929 ± 1.075
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
3.929MetVal: 3.929 ± 1.775
1.965MetTrp: 1.965 ± 0.888
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.929AsnAla: 3.929 ± 1.775
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
3.929AsnGly: 3.929 ± 1.775
0.0AsnHis: 0.0 ± 0.0
1.965AsnIle: 1.965 ± 0.888
0.0AsnLys: 0.0 ± 0.0
1.965AsnLeu: 1.965 ± 0.888
0.0AsnMet: 0.0 ± 0.0
1.965AsnAsn: 1.965 ± 0.888
3.929AsnPro: 3.929 ± 1.075
3.929AsnGln: 3.929 ± 1.075
7.859AsnArg: 7.859 ± 2.15
0.0AsnSer: 0.0 ± 0.0
0.0AsnThr: 0.0 ± 0.0
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.965ProAla: 1.965 ± 0.888
0.0ProCys: 0.0 ± 0.0
1.965ProAsp: 1.965 ± 0.888
3.929ProGlu: 3.929 ± 1.775
1.965ProPhe: 1.965 ± 0.888
5.894ProGly: 5.894 ± 2.663
5.894ProHis: 5.894 ± 3.038
1.965ProIle: 1.965 ± 1.963
1.965ProLys: 1.965 ± 0.888
5.894ProLeu: 5.894 ± 0.188
0.0ProMet: 0.0 ± 0.0
5.894ProAsn: 5.894 ± 0.188
11.788ProPro: 11.788 ± 0.375
1.965ProGln: 1.965 ± 0.888
3.929ProArg: 3.929 ± 1.075
9.823ProSer: 9.823 ± 4.113
5.894ProThr: 5.894 ± 2.663
1.965ProVal: 1.965 ± 0.888
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
5.894GlnAla: 5.894 ± 5.889
1.965GlnCys: 1.965 ± 0.888
0.0GlnAsp: 0.0 ± 0.0
3.929GlnGlu: 3.929 ± 1.775
1.965GlnPhe: 1.965 ± 0.888
5.894GlnGly: 5.894 ± 2.663
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
5.894GlnLeu: 5.894 ± 2.663
3.929GlnMet: 3.929 ± 1.075
1.965GlnAsn: 1.965 ± 0.888
1.965GlnPro: 1.965 ± 1.963
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
5.894GlnSer: 5.894 ± 3.038
0.0GlnThr: 0.0 ± 0.0
1.965GlnVal: 1.965 ± 1.963
1.965GlnTrp: 1.965 ± 0.888
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
11.788ArgAla: 11.788 ± 3.226
0.0ArgCys: 0.0 ± 0.0
5.894ArgAsp: 5.894 ± 2.663
0.0ArgGlu: 0.0 ± 0.0
3.929ArgPhe: 3.929 ± 1.775
5.894ArgGly: 5.894 ± 2.663
3.929ArgHis: 3.929 ± 1.075
1.965ArgIle: 1.965 ± 0.888
3.929ArgLys: 3.929 ± 3.926
5.894ArgLeu: 5.894 ± 3.038
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
7.859ArgPro: 7.859 ± 2.15
9.823ArgGln: 9.823 ± 4.113
7.859ArgArg: 7.859 ± 3.551
9.823ArgSer: 9.823 ± 4.113
3.929ArgThr: 3.929 ± 3.926
7.859ArgVal: 7.859 ± 3.551
1.965ArgTrp: 1.965 ± 1.963
7.859ArgTyr: 7.859 ± 2.15
0.0ArgXaa: 0.0 ± 0.0
Ser
5.894SerAla: 5.894 ± 3.038
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
9.823SerGlu: 9.823 ± 1.588
1.965SerPhe: 1.965 ± 0.888
5.894SerGly: 5.894 ± 0.188
1.965SerHis: 1.965 ± 0.888
3.929SerIle: 3.929 ± 1.775
3.929SerLys: 3.929 ± 1.075
7.859SerLeu: 7.859 ± 3.551
1.965SerMet: 1.965 ± 1.963
1.965SerAsn: 1.965 ± 0.888
1.965SerPro: 1.965 ± 0.888
7.859SerGln: 7.859 ± 2.15
9.823SerArg: 9.823 ± 6.964
3.929SerSer: 3.929 ± 3.926
3.929SerThr: 3.929 ± 1.075
1.965SerVal: 1.965 ± 0.888
0.0SerTrp: 0.0 ± 0.0
5.894SerTyr: 5.894 ± 5.889
0.0SerXaa: 0.0 ± 0.0
Thr
1.965ThrAla: 1.965 ± 1.963
3.929ThrCys: 3.929 ± 1.075
0.0ThrAsp: 0.0 ± 0.0
1.965ThrGlu: 1.965 ± 0.888
0.0ThrPhe: 0.0 ± 0.0
3.929ThrGly: 3.929 ± 1.075
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
5.894ThrLys: 5.894 ± 0.188
5.894ThrLeu: 5.894 ± 2.663
0.0ThrMet: 0.0 ± 0.0
1.965ThrAsn: 1.965 ± 0.888
1.965ThrPro: 1.965 ± 1.963
0.0ThrGln: 0.0 ± 0.0
7.859ThrArg: 7.859 ± 3.551
1.965ThrSer: 1.965 ± 1.963
5.894ThrThr: 5.894 ± 3.038
1.965ThrVal: 1.965 ± 0.888
1.965ThrTrp: 1.965 ± 1.963
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
3.929ValGlu: 3.929 ± 1.775
1.965ValPhe: 1.965 ± 0.888
5.894ValGly: 5.894 ± 2.663
1.965ValHis: 1.965 ± 0.888
7.859ValIle: 7.859 ± 3.551
0.0ValLys: 0.0 ± 0.0
5.894ValLeu: 5.894 ± 0.188
3.929ValMet: 3.929 ± 1.075
0.0ValAsn: 0.0 ± 0.0
5.894ValPro: 5.894 ± 0.188
1.965ValGln: 1.965 ± 0.888
1.965ValArg: 1.965 ± 1.963
1.965ValSer: 1.965 ± 0.888
1.965ValThr: 1.965 ± 1.963
3.929ValVal: 3.929 ± 1.775
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.929TrpAla: 3.929 ± 1.075
3.929TrpCys: 3.929 ± 1.075
0.0TrpAsp: 0.0 ± 0.0
1.965TrpGlu: 1.965 ± 0.888
3.929TrpPhe: 3.929 ± 1.775
1.965TrpGly: 1.965 ± 0.888
0.0TrpHis: 0.0 ± 0.0
1.965TrpIle: 1.965 ± 0.888
1.965TrpLys: 1.965 ± 0.888
1.965TrpLeu: 1.965 ± 0.888
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.965TrpPro: 1.965 ± 0.888
1.965TrpGln: 1.965 ± 1.963
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.965TyrAla: 1.965 ± 1.963
1.965TyrCys: 1.965 ± 0.888
1.965TyrAsp: 1.965 ± 0.888
1.965TyrGlu: 1.965 ± 1.963
0.0TyrPhe: 0.0 ± 0.0
5.894TyrGly: 5.894 ± 3.038
3.929TyrHis: 3.929 ± 1.775
0.0TyrIle: 0.0 ± 0.0
1.965TyrLys: 1.965 ± 0.888
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.965TyrPro: 1.965 ± 0.888
0.0TyrGln: 0.0 ± 0.0
11.788TyrArg: 11.788 ± 3.226
3.929TyrSer: 3.929 ± 3.926
0.0TyrThr: 0.0 ± 0.0
0.0TyrVal: 0.0 ± 0.0
1.965TyrTrp: 1.965 ± 0.888
1.965TyrTyr: 1.965 ± 0.888
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski