Amino acid dipepetide frequency for Heterocapsa circularisquama RNA virus 01 (strain 34) (HcRNAV01)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.843AlaAla: 8.843 ± 4.167
0.737AlaCys: 0.737 ± 1.084
3.685AlaAsp: 3.685 ± 1.945
5.158AlaGlu: 5.158 ± 0.222
3.685AlaPhe: 3.685 ± 0.473
8.106AlaGly: 8.106 ± 4.556
1.474AlaHis: 1.474 ± 0.778
5.158AlaIle: 5.158 ± 1.694
1.474AlaLys: 1.474 ± 0.694
8.106AlaLeu: 8.106 ± 3.083
4.422AlaMet: 4.422 ± 3.032
2.948AlaAsn: 2.948 ± 1.389
5.158AlaPro: 5.158 ± 0.222
2.211AlaGln: 2.211 ± 1.778
6.632AlaArg: 6.632 ± 0.556
4.422AlaSer: 4.422 ± 2.334
3.685AlaThr: 3.685 ± 0.473
5.895AlaVal: 5.895 ± 1.64
2.211AlaTrp: 2.211 ± 0.305
1.474AlaTyr: 1.474 ± 0.778
0.0AlaXaa: 0.0 ± 0.0
Cys
0.737CysAla: 0.737 ± 1.084
0.0CysCys: 0.0 ± 0.0
1.474CysAsp: 1.474 ± 0.778
0.737CysGlu: 0.737 ± 0.389
0.737CysPhe: 0.737 ± 0.389
2.211CysGly: 2.211 ± 1.167
0.0CysHis: 0.0 ± 0.0
0.737CysIle: 0.737 ± 0.389
0.0CysLys: 0.0 ± 0.0
0.737CysLeu: 0.737 ± 1.084
0.0CysMet: 0.0 ± 0.321
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.737CysGln: 0.737 ± 0.389
0.737CysArg: 0.737 ± 0.389
0.737CysSer: 0.737 ± 0.389
2.211CysThr: 2.211 ± 1.167
0.737CysVal: 0.737 ± 1.084
0.737CysTrp: 0.737 ± 1.084
0.737CysTyr: 0.737 ± 0.389
0.0CysXaa: 0.0 ± 0.0
Asp
3.685AspAla: 3.685 ± 0.473
0.0AspCys: 0.0 ± 0.0
3.685AspAsp: 3.685 ± 0.473
4.422AspGlu: 4.422 ± 2.334
3.685AspPhe: 3.685 ± 0.473
5.158AspGly: 5.158 ± 2.723
0.737AspHis: 0.737 ± 0.389
2.211AspIle: 2.211 ± 1.778
2.948AspLys: 2.948 ± 0.084
4.422AspLeu: 4.422 ± 2.334
2.211AspMet: 2.211 ± 0.305
1.474AspAsn: 1.474 ± 0.694
3.685AspPro: 3.685 ± 1.945
2.948AspGln: 2.948 ± 1.556
0.0AspArg: 0.0 ± 0.0
3.685AspSer: 3.685 ± 1.0
1.474AspThr: 1.474 ± 0.778
2.948AspVal: 2.948 ± 0.084
0.737AspTrp: 0.737 ± 0.389
2.211AspTyr: 2.211 ± 1.167
0.0AspXaa: 0.0 ± 0.0
Glu
5.895GluAla: 5.895 ± 1.64
0.737GluCys: 0.737 ± 0.389
2.211GluAsp: 2.211 ± 1.167
3.685GluGlu: 3.685 ± 1.945
0.0GluPhe: 0.0 ± 0.0
3.685GluGly: 3.685 ± 1.0
2.948GluHis: 2.948 ± 0.084
0.737GluIle: 0.737 ± 0.389
0.0GluLys: 0.0 ± 0.0
5.158GluLeu: 5.158 ± 2.723
1.474GluMet: 1.474 ± 0.778
2.211GluAsn: 2.211 ± 1.167
2.211GluPro: 2.211 ± 1.167
0.737GluGln: 0.737 ± 0.389
2.948GluArg: 2.948 ± 0.084
6.632GluSer: 6.632 ± 3.501
2.948GluThr: 2.948 ± 0.084
1.474GluVal: 1.474 ± 0.694
2.211GluTrp: 2.211 ± 1.778
2.211GluTyr: 2.211 ± 1.167
0.0GluXaa: 0.0 ± 0.0
Phe
1.474PheAla: 1.474 ± 0.694
0.0PheCys: 0.0 ± 0.0
4.422PheAsp: 4.422 ± 0.862
0.737PheGlu: 0.737 ± 0.389
0.737PhePhe: 0.737 ± 0.389
2.211PheGly: 2.211 ± 1.778
0.737PheHis: 0.737 ± 1.084
0.0PheIle: 0.0 ± 0.0
1.474PheLys: 1.474 ± 0.778
4.422PheLeu: 4.422 ± 2.334
0.737PheMet: 0.737 ± 1.084
2.948PheAsn: 2.948 ± 0.084
1.474PhePro: 1.474 ± 0.694
0.0PheGln: 0.0 ± 0.0
2.948PheArg: 2.948 ± 1.556
3.685PheSer: 3.685 ± 0.473
2.211PheThr: 2.211 ± 1.167
3.685PheVal: 3.685 ± 1.0
0.737PheTrp: 0.737 ± 0.389
0.737PheTyr: 0.737 ± 0.389
0.0PheXaa: 0.0 ± 0.0
Gly
9.58GlyAla: 9.58 ± 2.112
1.474GlyCys: 1.474 ± 0.694
4.422GlyAsp: 4.422 ± 0.862
5.895GlyGlu: 5.895 ± 3.112
2.948GlyPhe: 2.948 ± 1.556
12.528GlyGly: 12.528 ± 8.112
3.685GlyHis: 3.685 ± 1.0
5.895GlyIle: 5.895 ± 2.778
4.422GlyLys: 4.422 ± 0.611
7.369GlyLeu: 7.369 ± 0.945
2.948GlyMet: 2.948 ± 0.084
2.948GlyAsn: 2.948 ± 2.861
7.369GlyPro: 7.369 ± 0.945
2.211GlyGln: 2.211 ± 1.167
5.158GlyArg: 5.158 ± 0.222
7.369GlySer: 7.369 ± 6.417
4.422GlyThr: 4.422 ± 0.862
5.158GlyVal: 5.158 ± 1.251
2.211GlyTrp: 2.211 ± 1.167
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.737HisCys: 0.737 ± 0.389
0.737HisAsp: 0.737 ± 0.389
0.0HisGlu: 0.0 ± 0.0
1.474HisPhe: 1.474 ± 0.778
2.948HisGly: 2.948 ± 1.389
1.474HisHis: 1.474 ± 0.694
0.0HisIle: 0.0 ± 0.0
0.737HisLys: 0.737 ± 0.389
2.948HisLeu: 2.948 ± 0.084
0.737HisMet: 0.737 ± 0.389
1.474HisAsn: 1.474 ± 0.778
1.474HisPro: 1.474 ± 0.694
0.0HisGln: 0.0 ± 0.0
2.211HisArg: 2.211 ± 1.167
0.737HisSer: 0.737 ± 0.389
2.948HisThr: 2.948 ± 0.084
1.474HisVal: 1.474 ± 0.778
0.0HisTrp: 0.0 ± 0.0
1.474HisTyr: 1.474 ± 0.694
0.0HisXaa: 0.0 ± 0.0
Ile
4.422IleAla: 4.422 ± 3.556
2.211IleCys: 2.211 ± 1.167
1.474IleAsp: 1.474 ± 0.778
1.474IleGlu: 1.474 ± 0.778
1.474IlePhe: 1.474 ± 0.694
2.948IleGly: 2.948 ± 0.084
0.0IleHis: 0.0 ± 0.0
0.737IleIle: 0.737 ± 0.389
2.211IleLys: 2.211 ± 0.305
2.211IleLeu: 2.211 ± 1.167
0.737IleMet: 0.737 ± 1.084
2.948IleAsn: 2.948 ± 0.084
2.211IlePro: 2.211 ± 1.167
0.0IleGln: 0.0 ± 0.0
2.211IleArg: 2.211 ± 1.167
2.211IleSer: 2.211 ± 0.305
4.422IleThr: 4.422 ± 2.083
0.737IleVal: 0.737 ± 0.389
0.737IleTrp: 0.737 ± 0.389
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.422LysAla: 4.422 ± 2.334
0.0LysCys: 0.0 ± 0.0
2.211LysAsp: 2.211 ± 1.167
0.0LysGlu: 0.0 ± 0.0
1.474LysPhe: 1.474 ± 0.778
5.895LysGly: 5.895 ± 3.112
0.0LysHis: 0.0 ± 0.0
0.737LysIle: 0.737 ± 0.389
2.948LysLys: 2.948 ± 1.556
5.158LysLeu: 5.158 ± 0.222
0.0LysMet: 0.0 ± 0.0
1.474LysAsn: 1.474 ± 0.778
0.0LysPro: 0.0 ± 0.0
1.474LysGln: 1.474 ± 0.694
2.211LysArg: 2.211 ± 1.167
1.474LysSer: 1.474 ± 0.778
1.474LysThr: 1.474 ± 0.694
1.474LysVal: 1.474 ± 0.694
0.737LysTrp: 0.737 ± 1.084
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
7.369LeuAla: 7.369 ± 3.472
1.474LeuCys: 1.474 ± 0.778
2.211LeuAsp: 2.211 ± 0.305
1.474LeuGlu: 1.474 ± 0.778
2.211LeuPhe: 2.211 ± 0.305
6.632LeuGly: 6.632 ± 3.501
1.474LeuHis: 1.474 ± 0.778
5.895LeuIle: 5.895 ± 1.64
2.948LeuLys: 2.948 ± 1.556
5.895LeuLeu: 5.895 ± 3.112
4.422LeuMet: 4.422 ± 2.083
5.158LeuAsn: 5.158 ± 0.222
4.422LeuPro: 4.422 ± 0.611
1.474LeuGln: 1.474 ± 0.778
7.369LeuArg: 7.369 ± 2.418
6.632LeuSer: 6.632 ± 2.389
8.106LeuThr: 8.106 ± 1.334
6.632LeuVal: 6.632 ± 0.556
2.211LeuTrp: 2.211 ± 1.167
3.685LeuTyr: 3.685 ± 1.945
0.0LeuXaa: 0.0 ± 0.0
Met
0.737MetAla: 0.737 ± 1.084
0.0MetCys: 0.0 ± 0.0
1.474MetAsp: 1.474 ± 0.694
2.211MetGlu: 2.211 ± 0.305
0.737MetPhe: 0.737 ± 0.389
3.685MetGly: 3.685 ± 0.473
0.737MetHis: 0.737 ± 0.389
1.474MetIle: 1.474 ± 0.694
1.474MetLys: 1.474 ± 0.778
0.737MetLeu: 0.737 ± 1.084
0.0MetMet: 0.0 ± 0.0
1.474MetAsn: 1.474 ± 2.167
1.474MetPro: 1.474 ± 2.167
0.0MetGln: 0.0 ± 0.0
1.474MetArg: 1.474 ± 2.167
4.422MetSer: 4.422 ± 2.083
1.474MetThr: 1.474 ± 0.694
2.948MetVal: 2.948 ± 1.389
1.474MetTrp: 1.474 ± 0.778
0.737MetTyr: 0.737 ± 0.389
0.0MetXaa: 0.0 ± 0.0
Asn
3.685AsnAla: 3.685 ± 2.472
1.474AsnCys: 1.474 ± 0.694
2.948AsnAsp: 2.948 ± 0.084
3.685AsnGlu: 3.685 ± 0.473
0.737AsnPhe: 0.737 ± 1.084
4.422AsnGly: 4.422 ± 3.556
0.737AsnHis: 0.737 ± 0.389
0.737AsnIle: 0.737 ± 0.389
0.0AsnLys: 0.0 ± 0.0
5.158AsnLeu: 5.158 ± 1.251
0.737AsnMet: 0.737 ± 1.084
1.474AsnAsn: 1.474 ± 2.167
2.948AsnPro: 2.948 ± 2.861
0.737AsnGln: 0.737 ± 0.389
2.948AsnArg: 2.948 ± 0.084
0.737AsnSer: 0.737 ± 0.389
1.474AsnThr: 1.474 ± 2.167
2.211AsnVal: 2.211 ± 0.305
0.737AsnTrp: 0.737 ± 0.389
0.737AsnTyr: 0.737 ± 1.084
0.0AsnXaa: 0.0 ± 0.0
Pro
4.422ProAla: 4.422 ± 3.556
0.0ProCys: 0.0 ± 0.0
2.948ProAsp: 2.948 ± 1.556
4.422ProGlu: 4.422 ± 0.611
2.948ProPhe: 2.948 ± 1.389
4.422ProGly: 4.422 ± 0.611
2.211ProHis: 2.211 ± 1.167
0.0ProIle: 0.0 ± 0.0
0.0ProLys: 0.0 ± 0.0
7.369ProLeu: 7.369 ± 3.472
0.737ProMet: 0.737 ± 1.084
1.474ProAsn: 1.474 ± 0.694
5.895ProPro: 5.895 ± 1.64
0.737ProGln: 0.737 ± 0.389
6.632ProArg: 6.632 ± 2.389
5.895ProSer: 5.895 ± 1.64
2.211ProThr: 2.211 ± 1.167
8.843ProVal: 8.843 ± 4.668
0.0ProTrp: 0.0 ± 0.0
0.737ProTyr: 0.737 ± 1.084
0.0ProXaa: 0.0 ± 0.0
Gln
2.211GlnAla: 2.211 ± 1.167
0.0GlnCys: 0.0 ± 0.0
0.737GlnAsp: 0.737 ± 0.389
1.474GlnGlu: 1.474 ± 0.778
0.0GlnPhe: 0.0 ± 0.0
4.422GlnGly: 4.422 ± 2.083
0.0GlnHis: 0.0 ± 0.0
0.737GlnIle: 0.737 ± 0.389
0.0GlnLys: 0.0 ± 0.0
3.685GlnLeu: 3.685 ± 0.473
0.0GlnMet: 0.0 ± 0.0
1.474GlnAsn: 1.474 ± 0.778
0.737GlnPro: 0.737 ± 0.389
0.737GlnGln: 0.737 ± 0.389
2.211GlnArg: 2.211 ± 1.778
2.948GlnSer: 2.948 ± 1.556
0.737GlnThr: 0.737 ± 1.084
1.474GlnVal: 1.474 ± 0.694
1.474GlnTrp: 1.474 ± 0.778
1.474GlnTyr: 1.474 ± 0.778
0.0GlnXaa: 0.0 ± 0.0
Arg
5.158ArgAla: 5.158 ± 0.222
0.737ArgCys: 0.737 ± 0.389
2.948ArgAsp: 2.948 ± 1.556
5.895ArgGlu: 5.895 ± 3.112
2.211ArgPhe: 2.211 ± 0.305
6.632ArgGly: 6.632 ± 0.916
1.474ArgHis: 1.474 ± 0.694
3.685ArgIle: 3.685 ± 1.945
2.211ArgLys: 2.211 ± 1.167
5.895ArgLeu: 5.895 ± 1.64
0.737ArgMet: 0.737 ± 0.389
2.948ArgAsn: 2.948 ± 1.389
2.948ArgPro: 2.948 ± 2.861
4.422ArgGln: 4.422 ± 0.611
9.58ArgArg: 9.58 ± 6.723
5.895ArgSer: 5.895 ± 0.167
5.158ArgThr: 5.158 ± 1.694
4.422ArgVal: 4.422 ± 0.611
0.0ArgTrp: 0.0 ± 0.0
0.737ArgTyr: 0.737 ± 0.389
0.0ArgXaa: 0.0 ± 0.0
Ser
7.369SerAla: 7.369 ± 0.527
0.0SerCys: 0.0 ± 0.0
5.895SerAsp: 5.895 ± 0.167
0.737SerGlu: 0.737 ± 0.389
4.422SerPhe: 4.422 ± 0.611
6.632SerGly: 6.632 ± 2.029
2.211SerHis: 2.211 ± 0.305
4.422SerIle: 4.422 ± 0.862
3.685SerLys: 3.685 ± 1.945
7.369SerLeu: 7.369 ± 2.418
3.685SerMet: 3.685 ± 0.473
0.737SerAsn: 0.737 ± 1.084
3.685SerPro: 3.685 ± 1.945
0.0SerGln: 0.0 ± 0.0
5.158SerArg: 5.158 ± 1.694
6.632SerSer: 6.632 ± 2.389
6.632SerThr: 6.632 ± 0.556
5.895SerVal: 5.895 ± 2.778
1.474SerTrp: 1.474 ± 2.167
3.685SerTyr: 3.685 ± 0.473
0.0SerXaa: 0.0 ± 0.0
Thr
7.369ThrAla: 7.369 ± 0.945
0.737ThrCys: 0.737 ± 0.389
1.474ThrAsp: 1.474 ± 0.694
3.685ThrGlu: 3.685 ± 1.0
1.474ThrPhe: 1.474 ± 0.778
5.895ThrGly: 5.895 ± 0.167
2.211ThrHis: 2.211 ± 1.167
0.737ThrIle: 0.737 ± 0.389
3.685ThrLys: 3.685 ± 1.945
1.474ThrLeu: 1.474 ± 0.778
2.211ThrMet: 2.211 ± 1.778
2.211ThrAsn: 2.211 ± 3.251
6.632ThrPro: 6.632 ± 2.029
2.948ThrGln: 2.948 ± 0.084
2.948ThrArg: 2.948 ± 0.084
5.895ThrSer: 5.895 ± 0.167
7.369ThrThr: 7.369 ± 0.945
2.948ThrVal: 2.948 ± 2.861
0.737ThrTrp: 0.737 ± 1.084
1.474ThrTyr: 1.474 ± 0.778
0.0ThrXaa: 0.0 ± 0.0
Val
5.895ValAla: 5.895 ± 2.778
2.948ValCys: 2.948 ± 1.556
2.211ValAsp: 2.211 ± 1.167
2.948ValGlu: 2.948 ± 0.084
2.948ValPhe: 2.948 ± 0.084
7.369ValGly: 7.369 ± 0.945
0.0ValHis: 0.0 ± 0.0
0.737ValIle: 0.737 ± 1.084
2.211ValLys: 2.211 ± 1.167
4.422ValLeu: 4.422 ± 0.862
2.211ValMet: 2.211 ± 1.778
0.737ValAsn: 0.737 ± 1.084
5.895ValPro: 5.895 ± 1.305
3.685ValGln: 3.685 ± 1.0
5.158ValArg: 5.158 ± 0.222
8.106ValSer: 8.106 ± 1.334
1.474ValThr: 1.474 ± 0.778
3.685ValVal: 3.685 ± 1.0
1.474ValTrp: 1.474 ± 0.778
1.474ValTyr: 1.474 ± 0.694
0.0ValXaa: 0.0 ± 0.0
Trp
2.211TrpAla: 2.211 ± 1.167
0.0TrpCys: 0.0 ± 0.0
2.948TrpAsp: 2.948 ± 1.389
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.737TrpHis: 0.737 ± 0.389
0.0TrpIle: 0.0 ± 0.0
0.737TrpLys: 0.737 ± 1.084
2.948TrpLeu: 2.948 ± 0.084
0.0TrpMet: 0.0 ± 0.0
1.474TrpAsn: 1.474 ± 0.694
2.211TrpPro: 2.211 ± 0.305
0.0TrpGln: 0.0 ± 0.0
2.211TrpArg: 2.211 ± 0.305
2.211TrpSer: 2.211 ± 1.167
1.474TrpThr: 1.474 ± 0.694
1.474TrpVal: 1.474 ± 0.778
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.474TyrCys: 1.474 ± 0.694
2.211TyrAsp: 2.211 ± 1.167
1.474TyrGlu: 1.474 ± 0.778
1.474TyrPhe: 1.474 ± 0.778
2.211TyrGly: 2.211 ± 1.167
0.737TyrHis: 0.737 ± 0.389
0.737TyrIle: 0.737 ± 0.389
0.0TyrLys: 0.0 ± 0.0
2.211TyrLeu: 2.211 ± 0.305
0.0TyrMet: 0.0 ± 0.0
0.737TyrAsn: 0.737 ± 0.389
1.474TyrPro: 1.474 ± 2.167
1.474TyrGln: 1.474 ± 0.778
2.948TyrArg: 2.948 ± 1.556
0.0TyrSer: 0.0 ± 0.0
2.211TyrThr: 2.211 ± 0.305
1.474TyrVal: 1.474 ± 0.778
0.737TyrTrp: 0.737 ± 0.389
1.474TyrTyr: 1.474 ± 0.778
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1358 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski