Amino acid dipepetide frequency for Providence virus (isolate Helicoverpa zea/United States/vFLM1/-) (PRVFL)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.544AlaAla: 5.544 ± 1.773
0.924AlaCys: 0.924 ± 0.694
3.08AlaAsp: 3.08 ± 0.482
5.236AlaGlu: 5.236 ± 0.863
1.232AlaPhe: 1.232 ± 0.256
5.236AlaGly: 5.236 ± 1.411
2.156AlaHis: 2.156 ± 0.634
2.772AlaIle: 2.772 ± 0.634
2.772AlaLys: 2.772 ± 0.74
9.855AlaLeu: 9.855 ± 1.765
1.54AlaMet: 1.54 ± 0.385
2.156AlaAsn: 2.156 ± 1.079
3.388AlaPro: 3.388 ± 1.15
3.696AlaGln: 3.696 ± 0.499
6.468AlaArg: 6.468 ± 0.894
8.007AlaSer: 8.007 ± 1.705
7.391AlaThr: 7.391 ± 0.922
8.007AlaVal: 8.007 ± 1.509
1.54AlaTrp: 1.54 ± 0.873
1.232AlaTyr: 1.232 ± 0.608
0.0AlaXaa: 0.0 ± 0.0
Cys
1.232CysAla: 1.232 ± 0.608
0.308CysCys: 0.308 ± 0.231
1.232CysAsp: 1.232 ± 0.456
2.156CysGlu: 2.156 ± 0.651
0.616CysPhe: 0.616 ± 0.48
0.924CysGly: 0.924 ± 0.694
1.54CysHis: 1.54 ± 0.624
1.54CysIle: 1.54 ± 0.707
1.54CysLys: 1.54 ± 0.693
0.924CysLeu: 0.924 ± 0.42
0.0CysMet: 0.0 ± 0.0
0.308CysAsn: 0.308 ± 0.231
0.924CysPro: 0.924 ± 0.215
1.232CysGln: 1.232 ± 0.456
1.54CysArg: 1.54 ± 0.873
0.616CysSer: 0.616 ± 0.228
0.924CysThr: 0.924 ± 0.375
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.616CysTyr: 0.616 ± 0.228
0.0CysXaa: 0.0 ± 0.0
Asp
1.848AspAla: 1.848 ± 0.653
0.308AspCys: 0.308 ± 0.266
2.772AspAsp: 2.772 ± 0.63
1.232AspGlu: 1.232 ± 0.908
0.308AspPhe: 0.308 ± 0.266
4.312AspGly: 4.312 ± 1.042
0.308AspHis: 0.308 ± 0.266
1.232AspIle: 1.232 ± 0.797
0.616AspLys: 0.616 ± 0.463
4.312AspLeu: 4.312 ± 0.956
1.54AspMet: 1.54 ± 0.645
1.54AspAsn: 1.54 ± 0.822
4.928AspPro: 4.928 ± 0.727
2.772AspGln: 2.772 ± 0.858
2.156AspArg: 2.156 ± 0.281
2.464AspSer: 2.464 ± 1.074
2.156AspThr: 2.156 ± 1.42
2.772AspVal: 2.772 ± 0.68
0.924AspTrp: 0.924 ± 0.375
1.232AspTyr: 1.232 ± 0.517
0.0AspXaa: 0.0 ± 0.0
Glu
2.156GluAla: 2.156 ± 1.014
1.232GluCys: 1.232 ± 0.256
1.848GluAsp: 1.848 ± 0.43
5.544GluGlu: 5.544 ± 2.264
3.08GluPhe: 3.08 ± 0.449
4.004GluGly: 4.004 ± 1.112
2.464GluHis: 2.464 ± 1.034
2.156GluIle: 2.156 ± 0.675
3.08GluLys: 3.08 ± 1.154
3.696GluLeu: 3.696 ± 0.997
1.232GluMet: 1.232 ± 0.478
2.156GluAsn: 2.156 ± 1.084
3.388GluPro: 3.388 ± 0.201
2.772GluGln: 2.772 ± 0.644
1.848GluArg: 1.848 ± 0.653
4.312GluSer: 4.312 ± 0.827
2.772GluThr: 2.772 ± 0.68
4.004GluVal: 4.004 ± 0.347
1.232GluTrp: 1.232 ± 0.479
1.54GluTyr: 1.54 ± 0.439
0.0GluXaa: 0.0 ± 0.0
Phe
3.696PheAla: 3.696 ± 0.956
1.54PheCys: 1.54 ± 1.086
0.924PheAsp: 0.924 ± 0.375
1.54PheGlu: 1.54 ± 0.775
0.616PhePhe: 0.616 ± 0.366
0.616PheGly: 0.616 ± 0.281
0.616PheHis: 0.616 ± 0.366
0.924PheIle: 0.924 ± 0.921
0.308PheLys: 0.308 ± 0.231
0.924PheLeu: 0.924 ± 0.46
0.308PheMet: 0.308 ± 0.231
0.308PheAsn: 0.308 ± 0.307
1.232PhePro: 1.232 ± 0.393
2.464PheGln: 2.464 ± 0.397
1.54PheArg: 1.54 ± 0.424
2.156PheSer: 2.156 ± 1.381
1.54PheThr: 1.54 ± 0.27
2.156PheVal: 2.156 ± 0.904
0.616PheTrp: 0.616 ± 0.366
0.924PheTyr: 0.924 ± 0.46
0.0PheXaa: 0.0 ± 0.0
Gly
5.544GlyAla: 5.544 ± 1.575
0.616GlyCys: 0.616 ± 0.463
4.62GlyAsp: 4.62 ± 1.105
4.312GlyGlu: 4.312 ± 0.827
0.924GlyPhe: 0.924 ± 0.413
7.699GlyGly: 7.699 ± 3.7
2.156GlyHis: 2.156 ± 1.251
4.004GlyIle: 4.004 ± 1.361
4.312GlyLys: 4.312 ± 1.237
5.236GlyLeu: 5.236 ± 0.321
0.308GlyMet: 0.308 ± 0.266
3.08GlyAsn: 3.08 ± 0.482
4.312GlyPro: 4.312 ± 1.4
1.848GlyGln: 1.848 ± 0.827
6.468GlyArg: 6.468 ± 1.989
6.775GlySer: 6.775 ± 2.273
4.928GlyThr: 4.928 ± 0.986
3.388GlyVal: 3.388 ± 1.224
2.464GlyTrp: 2.464 ± 0.959
2.156GlyTyr: 2.156 ± 0.281
0.0GlyXaa: 0.0 ± 0.0
His
2.464HisAla: 2.464 ± 0.739
0.308HisCys: 0.308 ± 0.231
0.0HisAsp: 0.0 ± 0.0
2.156HisGlu: 2.156 ± 0.876
0.924HisPhe: 0.924 ± 0.413
1.848HisGly: 1.848 ± 1.024
0.616HisHis: 0.616 ± 0.463
1.848HisIle: 1.848 ± 0.245
1.232HisLys: 1.232 ± 0.579
1.848HisLeu: 1.848 ± 0.972
0.924HisMet: 0.924 ± 0.627
1.232HisAsn: 1.232 ± 0.579
1.54HisPro: 1.54 ± 0.624
0.308HisGln: 0.308 ± 0.231
1.232HisArg: 1.232 ± 0.297
1.54HisSer: 1.54 ± 0.799
2.464HisThr: 2.464 ± 0.718
2.772HisVal: 2.772 ± 1.317
0.616HisTrp: 0.616 ± 0.48
0.924HisTyr: 0.924 ± 0.621
0.0HisXaa: 0.0 ± 0.0
Ile
1.54IleAla: 1.54 ± 0.693
1.232IleCys: 1.232 ± 0.393
2.464IleAsp: 2.464 ± 0.959
1.848IleGlu: 1.848 ± 1.241
0.924IlePhe: 0.924 ± 0.46
2.156IleGly: 2.156 ± 0.569
0.308IleHis: 0.308 ± 0.231
1.232IleIle: 1.232 ± 0.835
1.232IleLys: 1.232 ± 0.562
3.388IleLeu: 3.388 ± 1.189
1.54IleMet: 1.54 ± 0.385
0.924IleAsn: 0.924 ± 0.215
6.468IlePro: 6.468 ± 1.71
0.616IleGln: 0.616 ± 0.366
2.464IleArg: 2.464 ± 0.677
4.004IleSer: 4.004 ± 1.417
2.156IleThr: 2.156 ± 1.372
3.388IleVal: 3.388 ± 1.395
0.308IleTrp: 0.308 ± 0.231
1.232IleTyr: 1.232 ± 0.256
0.0IleXaa: 0.0 ± 0.0
Lys
3.696LysAla: 3.696 ± 0.499
0.616LysCys: 0.616 ± 0.463
1.232LysAsp: 1.232 ± 0.517
2.156LysGlu: 2.156 ± 0.281
0.924LysPhe: 0.924 ± 0.413
3.388LysGly: 3.388 ± 0.653
0.616LysHis: 0.616 ± 0.228
0.308LysIle: 0.308 ± 0.231
0.308LysLys: 0.308 ± 0.231
2.464LysLeu: 2.464 ± 0.592
0.924LysMet: 0.924 ± 0.55
2.772LysAsn: 2.772 ± 0.561
3.388LysPro: 3.388 ± 0.797
1.848LysGln: 1.848 ± 0.653
1.232LysArg: 1.232 ± 0.478
4.004LysSer: 4.004 ± 1.08
2.156LysThr: 2.156 ± 1.014
2.464LysVal: 2.464 ± 0.494
0.616LysTrp: 0.616 ± 0.531
1.54LysTyr: 1.54 ± 0.424
0.308LysXaa: 0.308 ± 0.266
Leu
7.083LeuAla: 7.083 ± 1.637
1.848LeuCys: 1.848 ± 0.405
2.772LeuAsp: 2.772 ± 1.072
4.004LeuGlu: 4.004 ± 0.233
2.156LeuPhe: 2.156 ± 0.651
5.852LeuGly: 5.852 ± 1.58
1.54LeuHis: 1.54 ± 0.575
1.848LeuIle: 1.848 ± 1.007
3.08LeuLys: 3.08 ± 0.561
11.703LeuLeu: 11.703 ± 4.189
2.156LeuMet: 2.156 ± 1.259
2.464LeuAsn: 2.464 ± 0.595
6.468LeuPro: 6.468 ± 0.724
4.312LeuGln: 4.312 ± 1.004
11.087LeuArg: 11.087 ± 4.815
10.163LeuSer: 10.163 ± 3.201
7.083LeuThr: 7.083 ± 2.178
6.16LeuVal: 6.16 ± 1.468
1.54LeuTrp: 1.54 ± 0.785
1.54LeuTyr: 1.54 ± 0.498
0.0LeuXaa: 0.0 ± 0.0
Met
1.232MetAla: 1.232 ± 0.256
0.924MetCys: 0.924 ± 0.627
1.54MetAsp: 1.54 ± 0.553
2.464MetGlu: 2.464 ± 0.368
0.0MetPhe: 0.0 ± 0.0
1.232MetGly: 1.232 ± 0.586
1.232MetHis: 1.232 ± 0.393
0.616MetIle: 0.616 ± 0.48
1.232MetLys: 1.232 ± 0.479
1.848MetLeu: 1.848 ± 1.255
0.0MetMet: 0.0 ± 0.0
0.308MetAsn: 0.308 ± 0.307
0.308MetPro: 0.308 ± 0.307
0.616MetGln: 0.616 ± 0.281
0.616MetArg: 0.616 ± 0.228
1.54MetSer: 1.54 ± 0.785
2.464MetThr: 2.464 ± 1.588
0.616MetVal: 0.616 ± 0.531
0.616MetTrp: 0.616 ± 0.531
0.308MetTyr: 0.308 ± 0.266
0.0MetXaa: 0.0 ± 0.0
Asn
2.464AsnAla: 2.464 ± 0.945
0.616AsnCys: 0.616 ± 0.228
0.308AsnAsp: 0.308 ± 0.231
0.924AsnGlu: 0.924 ± 0.215
1.232AsnPhe: 1.232 ± 1.228
2.156AsnGly: 2.156 ± 0.876
0.308AsnHis: 0.308 ± 0.231
2.156AsnIle: 2.156 ± 0.689
0.924AsnLys: 0.924 ± 0.215
4.312AsnLeu: 4.312 ± 1.275
0.924AsnMet: 0.924 ± 0.46
2.772AsnAsn: 2.772 ± 1.587
3.08AsnPro: 3.08 ± 1.027
0.616AsnGln: 0.616 ± 0.366
2.772AsnArg: 2.772 ± 0.361
3.388AsnSer: 3.388 ± 0.797
4.004AsnThr: 4.004 ± 0.721
4.312AsnVal: 4.312 ± 0.657
0.308AsnTrp: 0.308 ± 0.307
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
7.699ProAla: 7.699 ± 1.074
0.616ProCys: 0.616 ± 0.48
1.54ProAsp: 1.54 ± 0.27
3.696ProGlu: 3.696 ± 0.984
1.232ProPhe: 1.232 ± 0.586
4.004ProGly: 4.004 ± 1.514
0.308ProHis: 0.308 ± 0.231
1.54ProIle: 1.54 ± 0.668
3.08ProLys: 3.08 ± 0.881
5.544ProLeu: 5.544 ± 2.078
0.308ProMet: 0.308 ± 0.266
2.156ProAsn: 2.156 ± 0.689
4.312ProPro: 4.312 ± 0.96
4.004ProGln: 4.004 ± 0.441
3.696ProArg: 3.696 ± 1.054
6.16ProSer: 6.16 ± 0.556
5.852ProThr: 5.852 ± 1.91
6.468ProVal: 6.468 ± 0.834
1.232ProTrp: 1.232 ± 0.517
0.924ProTyr: 0.924 ± 0.375
0.0ProXaa: 0.0 ± 0.0
Gln
3.388GlnAla: 3.388 ± 1.034
0.924GlnCys: 0.924 ± 0.438
1.232GlnAsp: 1.232 ± 0.256
1.54GlnGlu: 1.54 ± 0.799
2.772GlnPhe: 2.772 ± 1.247
2.156GlnGly: 2.156 ± 1.268
2.772GlnHis: 2.772 ± 1.209
0.924GlnIle: 0.924 ± 0.375
1.54GlnLys: 1.54 ± 0.498
4.312GlnLeu: 4.312 ± 1.573
0.924GlnMet: 0.924 ± 0.621
1.54GlnAsn: 1.54 ± 0.908
1.848GlnPro: 1.848 ± 0.653
3.08GlnGln: 3.08 ± 0.668
1.848GlnArg: 1.848 ± 0.59
4.928GlnSer: 4.928 ± 1.108
1.848GlnThr: 1.848 ± 0.405
2.156GlnVal: 2.156 ± 0.564
0.616GlnTrp: 0.616 ± 0.281
0.924GlnTyr: 0.924 ± 0.694
0.0GlnXaa: 0.0 ± 0.0
Arg
6.468ArgAla: 6.468 ± 0.612
0.308ArgCys: 0.308 ± 0.231
3.08ArgAsp: 3.08 ± 1.241
2.772ArgGlu: 2.772 ± 0.662
1.848ArgPhe: 1.848 ± 0.748
5.852ArgGly: 5.852 ± 0.528
0.924ArgHis: 0.924 ± 0.42
1.848ArgIle: 1.848 ± 1.007
4.312ArgLys: 4.312 ± 0.729
7.083ArgLeu: 7.083 ± 0.725
1.848ArgMet: 1.848 ± 0.639
3.08ArgAsn: 3.08 ± 0.482
3.696ArgPro: 3.696 ± 0.774
1.848ArgGln: 1.848 ± 0.245
7.083ArgArg: 7.083 ± 1.66
5.544ArgSer: 5.544 ± 1.588
4.62ArgThr: 4.62 ± 1.354
4.928ArgVal: 4.928 ± 0.885
0.616ArgTrp: 0.616 ± 0.228
3.388ArgTyr: 3.388 ± 0.93
0.0ArgXaa: 0.0 ± 0.0
Ser
7.391SerAla: 7.391 ± 1.121
2.156SerCys: 2.156 ± 0.729
3.08SerAsp: 3.08 ± 0.877
4.312SerGlu: 4.312 ± 0.336
1.848SerPhe: 1.848 ± 0.804
9.239SerGly: 9.239 ± 1.446
3.08SerHis: 3.08 ± 1.039
4.004SerIle: 4.004 ± 2.458
2.156SerLys: 2.156 ± 0.602
9.547SerLeu: 9.547 ± 3.497
1.848SerMet: 1.848 ± 0.466
3.08SerAsn: 3.08 ± 0.712
5.236SerPro: 5.236 ± 1.32
2.772SerGln: 2.772 ± 0.662
5.852SerArg: 5.852 ± 0.87
7.391SerSer: 7.391 ± 0.277
2.772SerThr: 2.772 ± 0.724
7.699SerVal: 7.699 ± 2.336
0.924SerTrp: 0.924 ± 0.42
1.848SerTyr: 1.848 ± 1.024
0.0SerXaa: 0.0 ± 0.0
Thr
6.775ThrAla: 6.775 ± 0.905
1.848ThrCys: 1.848 ± 0.58
1.54ThrAsp: 1.54 ± 0.859
1.848ThrGlu: 1.848 ± 0.43
2.156ThrPhe: 2.156 ± 0.977
6.775ThrGly: 6.775 ± 1.578
2.464ThrHis: 2.464 ± 1.283
4.62ThrIle: 4.62 ± 0.958
2.156ThrLys: 2.156 ± 0.281
5.236ThrLeu: 5.236 ± 0.912
1.54ThrMet: 1.54 ± 0.553
3.696ThrAsn: 3.696 ± 1.074
3.08ThrPro: 3.08 ± 0.352
3.388ThrGln: 3.388 ± 0.756
5.236ThrArg: 5.236 ± 0.755
3.388ThrSer: 3.388 ± 0.441
6.468ThrThr: 6.468 ± 0.844
4.62ThrVal: 4.62 ± 2.457
0.924ThrTrp: 0.924 ± 0.627
0.924ThrTyr: 0.924 ± 0.541
0.0ThrXaa: 0.0 ± 0.0
Val
8.623ValAla: 8.623 ± 1.772
1.232ValCys: 1.232 ± 0.393
4.928ValAsp: 4.928 ± 1.162
4.312ValGlu: 4.312 ± 0.421
1.848ValPhe: 1.848 ± 0.653
4.928ValGly: 4.928 ± 2.149
2.156ValHis: 2.156 ± 0.938
3.388ValIle: 3.388 ± 0.713
1.848ValLys: 1.848 ± 0.724
8.007ValLeu: 8.007 ± 2.113
0.924ValMet: 0.924 ± 0.475
2.156ValAsn: 2.156 ± 0.356
4.312ValPro: 4.312 ± 1.116
1.848ValGln: 1.848 ± 0.487
4.62ValArg: 4.62 ± 0.881
6.468ValSer: 6.468 ± 1.359
4.62ValThr: 4.62 ± 1.45
6.16ValVal: 6.16 ± 0.659
1.232ValTrp: 1.232 ± 0.478
2.156ValTyr: 2.156 ± 0.938
0.0ValXaa: 0.0 ± 0.0
Trp
1.232TrpAla: 1.232 ± 0.256
0.616TrpCys: 0.616 ± 0.48
0.616TrpAsp: 0.616 ± 0.531
1.232TrpGlu: 1.232 ± 0.586
0.308TrpPhe: 0.308 ± 0.307
0.924TrpGly: 0.924 ± 0.413
0.308TrpHis: 0.308 ± 0.231
0.924TrpIle: 0.924 ± 0.627
0.0TrpLys: 0.0 ± 0.0
2.464TrpLeu: 2.464 ± 1.443
0.0TrpMet: 0.0 ± 0.0
1.232TrpAsn: 1.232 ± 0.517
0.308TrpPro: 0.308 ± 0.266
0.308TrpGln: 0.308 ± 0.231
2.464TrpArg: 2.464 ± 0.397
1.54TrpSer: 1.54 ± 0.439
0.924TrpThr: 0.924 ± 0.561
1.232TrpVal: 1.232 ± 0.586
1.232TrpTrp: 1.232 ± 0.586
0.308TrpTyr: 0.308 ± 0.307
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.156TyrAla: 2.156 ± 0.281
0.0TyrCys: 0.0 ± 0.0
0.924TyrAsp: 0.924 ± 0.541
1.232TyrGlu: 1.232 ± 0.256
0.0TyrPhe: 0.0 ± 0.0
1.848TyrGly: 1.848 ± 1.388
0.924TyrHis: 0.924 ± 0.438
1.54TyrIle: 1.54 ± 0.385
1.54TyrLys: 1.54 ± 0.806
2.156TyrLeu: 2.156 ± 1.177
0.616TyrMet: 0.616 ± 0.338
0.616TyrAsn: 0.616 ± 0.463
2.156TyrPro: 2.156 ± 0.245
0.616TyrGln: 0.616 ± 0.281
0.924TyrArg: 0.924 ± 0.42
1.848TyrSer: 1.848 ± 0.694
1.54TyrThr: 1.54 ± 0.498
2.464TyrVal: 2.464 ± 1.495
0.616TyrTrp: 0.616 ± 0.228
0.308TyrTyr: 0.308 ± 0.307
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.308XaaGln: 0.308 ± 0.266
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski