Amino acid dipepetide frequency for Suricata suricatta (Meerkat)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.96AlaAla: 6.96 ± 0.031	1.421AlaCys: 1.421 ± 0.011	3.004AlaAsp: 3.004 ± 0.013	4.855AlaGlu: 4.855 ± 0.023	2.59AlaPhe: 2.59 ± 0.012	4.96AlaGly: 4.96 ± 0.027	1.569AlaHis: 1.569 ± 0.009	2.712AlaIle: 2.712 ± 0.013	3.419AlaLys: 3.419 ± 0.019	7.215AlaLeu: 7.215 ± 0.031	1.468AlaMet: 1.468 ± 0.009	1.96AlaAsn: 1.96 ± 0.011	4.501AlaPro: 4.501 ± 0.027	3.325AlaGln: 3.325 ± 0.018	3.842AlaArg: 3.842 ± 0.019	5.924AlaSer: 5.924 ± 0.025	3.543AlaThr: 3.543 ± 0.016	4.808AlaVal: 4.808 ± 0.018	0.824AlaTrp: 0.824 ± 0.006	1.51AlaTyr: 1.51 ± 0.009	0.012AlaXaa: 0.012 ± 0.001
Cys	1.296CysAla: 1.296 ± 0.01	0.622CysCys: 0.622 ± 0.009	0.987CysAsp: 0.987 ± 0.009	1.28CysGlu: 1.28 ± 0.014	0.833CysPhe: 0.833 ± 0.007	1.719CysGly: 1.719 ± 0.018	0.659CysHis: 0.659 ± 0.008	0.908CysIle: 0.908 ± 0.008	1.1CysLys: 1.1 ± 0.01	2.165CysLeu: 2.165 ± 0.016	0.405CysMet: 0.405 ± 0.004	0.759CysAsn: 0.759 ± 0.008	1.414CysPro: 1.414 ± 0.013	1.059CysGln: 1.059 ± 0.011	1.335CysArg: 1.335 ± 0.011	1.979CysSer: 1.979 ± 0.013	1.078CysThr: 1.078 ± 0.009	1.347CysVal: 1.347 ± 0.012	0.29CysTrp: 0.29 ± 0.004	0.55CysTyr: 0.55 ± 0.006	0.001CysXaa: 0.001 ± 0.0
Asp	2.933AspAla: 2.933 ± 0.014	1.008AspCys: 1.008 ± 0.01	2.578AspAsp: 2.578 ± 0.014	3.399AspGlu: 3.399 ± 0.019	2.102AspPhe: 2.102 ± 0.012	3.352AspGly: 3.352 ± 0.02	1.134AspHis: 1.134 ± 0.008	2.504AspIle: 2.504 ± 0.013	2.489AspLys: 2.489 ± 0.013	5.024AspLeu: 5.024 ± 0.02	1.092AspMet: 1.092 ± 0.008	1.609AspAsn: 1.609 ± 0.011	2.923AspPro: 2.923 ± 0.012	1.833AspGln: 1.833 ± 0.01	2.492AspArg: 2.492 ± 0.016	4.168AspSer: 4.168 ± 0.019	2.45AspThr: 2.45 ± 0.013	3.096AspVal: 3.096 ± 0.015	0.615AspTrp: 0.615 ± 0.006	1.443AspTyr: 1.443 ± 0.009	0.002AspXaa: 0.002 ± 0.0
Glu	5.349GluAla: 5.349 ± 0.023	1.388GluCys: 1.388 ± 0.017	4.433GluAsp: 4.433 ± 0.019	8.001GluGlu: 8.001 ± 0.045	2.001GluPhe: 2.001 ± 0.01	4.307GluGly: 4.307 ± 0.017	1.502GluHis: 1.502 ± 0.01	3.116GluIle: 3.116 ± 0.018	5.34GluLys: 5.34 ± 0.033	6.469GluLeu: 6.469 ± 0.027	1.657GluMet: 1.657 ± 0.011	3.084GluAsn: 3.084 ± 0.016	3.377GluPro: 3.377 ± 0.021	3.167GluGln: 3.167 ± 0.018	4.069GluArg: 4.069 ± 0.022	4.404GluSer: 4.404 ± 0.02	3.376GluThr: 3.376 ± 0.015	4.204GluVal: 4.204 ± 0.019	0.695GluTrp: 0.695 ± 0.006	1.565GluTyr: 1.565 ± 0.014	0.003GluXaa: 0.003 ± 0.0
Phe	1.953PheAla: 1.953 ± 0.01	0.926PheCys: 0.926 ± 0.008	1.627PheAsp: 1.627 ± 0.01	1.983PheGlu: 1.983 ± 0.01	1.591PhePhe: 1.591 ± 0.013	2.141PheGly: 2.141 ± 0.011	1.017PheHis: 1.017 ± 0.008	1.782PheIle: 1.782 ± 0.012	1.738PheLys: 1.738 ± 0.01	4.053PheLeu: 4.053 ± 0.021	0.747PheMet: 0.747 ± 0.007	1.287PheAsn: 1.287 ± 0.009	2.017PhePro: 2.017 ± 0.011	1.76PheGln: 1.76 ± 0.01	1.983PheArg: 1.983 ± 0.013	3.354PheSer: 3.354 ± 0.017	1.981PheThr: 1.981 ± 0.011	2.131PheVal: 2.131 ± 0.012	0.483PheTrp: 0.483 ± 0.005	1.166PheTyr: 1.166 ± 0.008	0.001PheXaa: 0.001 ± 0.0
Gly	4.73GlyAla: 4.73 ± 0.022	1.31GlyCys: 1.31 ± 0.011	3.161GlyAsp: 3.161 ± 0.014	4.15GlyGlu: 4.15 ± 0.02	2.368GlyPhe: 2.368 ± 0.013	5.235GlyGly: 5.235 ± 0.034	1.74GlyHis: 1.74 ± 0.012	2.651GlyIle: 2.651 ± 0.014	3.744GlyLys: 3.744 ± 0.019	5.962GlyLeu: 5.962 ± 0.022	1.265GlyMet: 1.265 ± 0.01	2.292GlyAsn: 2.292 ± 0.011	4.515GlyPro: 4.515 ± 0.04	2.823GlyGln: 2.823 ± 0.015	3.979GlyArg: 3.979 ± 0.019	5.917GlySer: 5.917 ± 0.023	3.621GlyThr: 3.621 ± 0.015	3.606GlyVal: 3.606 ± 0.015	0.824GlyTrp: 0.824 ± 0.008	1.678GlyTyr: 1.678 ± 0.012	0.01GlyXaa: 0.01 ± 0.001
His	1.349HisAla: 1.349 ± 0.009	0.715HisCys: 0.715 ± 0.008	0.879HisAsp: 0.879 ± 0.007	1.308HisGlu: 1.308 ± 0.01	1.067HisPhe: 1.067 ± 0.009	1.551HisGly: 1.551 ± 0.01	0.878HisHis: 0.878 ± 0.008	1.21HisIle: 1.21 ± 0.009	1.228HisLys: 1.228 ± 0.008	2.912HisLeu: 2.912 ± 0.015	0.56HisMet: 0.56 ± 0.006	0.834HisAsn: 0.834 ± 0.007	1.673HisPro: 1.673 ± 0.012	1.316HisGln: 1.316 ± 0.012	1.646HisArg: 1.646 ± 0.009	2.251HisSer: 2.251 ± 0.012	1.487HisThr: 1.487 ± 0.013	1.54HisVal: 1.54 ± 0.009	0.339HisTrp: 0.339 ± 0.004	0.785HisTyr: 0.785 ± 0.007	0.002HisXaa: 0.002 ± 0.0
Ile	2.505IleAla: 2.505 ± 0.012	1.038IleCys: 1.038 ± 0.009	1.957IleAsp: 1.957 ± 0.013	2.528IleGlu: 2.528 ± 0.017	1.821IlePhe: 1.821 ± 0.012	2.16IleGly: 2.16 ± 0.011	1.281IleHis: 1.281 ± 0.011	2.306IleIle: 2.306 ± 0.016	2.561IleLys: 2.561 ± 0.016	4.463IleLeu: 4.463 ± 0.019	0.969IleMet: 0.969 ± 0.008	1.749IleAsn: 1.749 ± 0.01	2.522IlePro: 2.522 ± 0.013	2.21IleGln: 2.21 ± 0.012	2.351IleArg: 2.351 ± 0.012	3.596IleSer: 3.596 ± 0.016	2.477IleThr: 2.477 ± 0.019	2.443IleVal: 2.443 ± 0.014	0.489IleTrp: 0.489 ± 0.005	1.352IleTyr: 1.352 ± 0.008	0.001IleXaa: 0.001 ± 0.0
Lys	4.001LysAla: 4.001 ± 0.019	1.09LysCys: 1.09 ± 0.01	3.138LysAsp: 3.138 ± 0.019	5.104LysGlu: 5.104 ± 0.031	1.684LysPhe: 1.684 ± 0.009	3.238LysGly: 3.238 ± 0.021	1.377LysHis: 1.377 ± 0.011	2.689LysIle: 2.689 ± 0.017	4.629LysLys: 4.629 ± 0.025	5.102LysLeu: 5.102 ± 0.022	1.412LysMet: 1.412 ± 0.011	2.354LysAsn: 2.354 ± 0.013	3.154LysPro: 3.154 ± 0.021	2.573LysGln: 2.573 ± 0.016	3.268LysArg: 3.268 ± 0.018	3.882LysSer: 3.882 ± 0.018	3.064LysThr: 3.064 ± 0.014	3.451LysVal: 3.451 ± 0.019	0.601LysTrp: 0.601 ± 0.007	1.52LysTyr: 1.52 ± 0.011	0.002LysXaa: 0.002 ± 0.0
Leu	6.846LeuAla: 6.846 ± 0.027	2.204LeuCys: 2.204 ± 0.016	4.714LeuAsp: 4.714 ± 0.018	7.25LeuGlu: 7.25 ± 0.027	3.345LeuPhe: 3.345 ± 0.017	5.972LeuGly: 5.972 ± 0.023	2.726LeuHis: 2.726 ± 0.015	3.791LeuIle: 3.791 ± 0.016	5.747LeuLys: 5.747 ± 0.023	10.759LeuLeu: 10.759 ± 0.046	1.956LeuMet: 1.956 ± 0.011	3.423LeuAsn: 3.423 ± 0.015	6.115LeuPro: 6.115 ± 0.027	5.746LeuGln: 5.746 ± 0.024	6.129LeuArg: 6.129 ± 0.024	8.059LeuSer: 8.059 ± 0.026	5.065LeuThr: 5.065 ± 0.017	5.495LeuVal: 5.495 ± 0.024	1.141LeuTrp: 1.141 ± 0.008	2.461LeuTyr: 2.461 ± 0.013	0.006LeuXaa: 0.006 ± 0.001
Met	1.895MetAla: 1.895 ± 0.01	0.395MetCys: 0.395 ± 0.005	1.216MetAsp: 1.216 ± 0.008	1.802MetGlu: 1.802 ± 0.011	0.707MetPhe: 0.707 ± 0.008	1.252MetGly: 1.252 ± 0.008	0.45MetHis: 0.45 ± 0.004	0.806MetIle: 0.806 ± 0.007	1.423MetLys: 1.423 ± 0.01	1.934MetLeu: 1.934 ± 0.011	0.554MetMet: 0.554 ± 0.006	0.866MetAsn: 0.866 ± 0.007	1.068MetPro: 1.068 ± 0.009	0.896MetGln: 0.896 ± 0.007	1.036MetArg: 1.036 ± 0.007	1.547MetSer: 1.547 ± 0.01	1.116MetThr: 1.116 ± 0.007	1.368MetVal: 1.368 ± 0.008	0.231MetTrp: 0.231 ± 0.003	0.575MetTyr: 0.575 ± 0.006	0.001MetXaa: 0.001 ± 0.0
Asn	2.017AsnAla: 2.017 ± 0.011	0.8AsnCys: 0.8 ± 0.006	1.459AsnAsp: 1.459 ± 0.011	2.15AsnGlu: 2.15 ± 0.012	1.421AsnPhe: 1.421 ± 0.01	2.408AsnGly: 2.408 ± 0.014	0.905AsnHis: 0.905 ± 0.008	2.037AsnIle: 2.037 ± 0.012	2.178AsnLys: 2.178 ± 0.012	3.581AsnLeu: 3.581 ± 0.017	0.862AsnMet: 0.862 ± 0.007	1.448AsnAsn: 1.448 ± 0.01	2.121AsnPro: 2.121 ± 0.012	1.616AsnGln: 1.616 ± 0.01	1.807AsnArg: 1.807 ± 0.01	2.993AsnSer: 2.993 ± 0.015	1.876AsnThr: 1.876 ± 0.012	2.161AsnVal: 2.161 ± 0.012	0.432AsnTrp: 0.432 ± 0.004	1.063AsnTyr: 1.063 ± 0.008	0.001AsnXaa: 0.001 ± 0.0
Pro	5.189ProAla: 5.189 ± 0.028	1.186ProCys: 1.186 ± 0.011	2.805ProAsp: 2.805 ± 0.014	4.583ProGlu: 4.583 ± 0.021	1.932ProPhe: 1.932 ± 0.012	5.505ProGly: 5.505 ± 0.051	1.475ProHis: 1.475 ± 0.011	1.845ProIle: 1.845 ± 0.014	2.811ProLys: 2.811 ± 0.018	5.408ProLeu: 5.408 ± 0.021	1.045ProMet: 1.045 ± 0.008	1.775ProAsn: 1.775 ± 0.01	6.455ProPro: 6.455 ± 0.053	2.898ProGln: 2.898 ± 0.019	3.552ProArg: 3.552 ± 0.019	5.919ProSer: 5.919 ± 0.028	3.108ProThr: 3.108 ± 0.016	3.988ProVal: 3.988 ± 0.021	0.713ProTrp: 0.713 ± 0.007	1.458ProTyr: 1.458 ± 0.012	0.011ProXaa: 0.011 ± 0.001
Gln	3.572GlnAla: 3.572 ± 0.019	0.924GlnCys: 0.924 ± 0.01	2.352GlnAsp: 2.352 ± 0.013	3.925GlnGlu: 3.925 ± 0.02	1.338GlnPhe: 1.338 ± 0.009	2.88GlnGly: 2.88 ± 0.016	1.284GlnHis: 1.284 ± 0.009	1.944GlnIle: 1.944 ± 0.011	2.953GlnLys: 2.953 ± 0.018	4.674GlnLeu: 4.674 ± 0.024	1.114GlnMet: 1.114 ± 0.007	1.792GlnAsn: 1.792 ± 0.01	2.82GlnPro: 2.82 ± 0.018	2.983GlnGln: 2.983 ± 0.027	3.008GlnArg: 3.008 ± 0.016	3.121GlnSer: 3.121 ± 0.015	2.293GlnThr: 2.293 ± 0.011	2.814GlnVal: 2.814 ± 0.013	0.533GlnTrp: 0.533 ± 0.005	1.119GlnTyr: 1.119 ± 0.008	0.002GlnXaa: 0.002 ± 0.0
Arg	4.065ArgAla: 4.065 ± 0.021	1.24ArgCys: 1.24 ± 0.013	2.778ArgAsp: 2.778 ± 0.015	4.113ArgGlu: 4.113 ± 0.02	1.837ArgPhe: 1.837 ± 0.01	3.784ArgGly: 3.784 ± 0.023	1.55ArgHis: 1.55 ± 0.009	2.401ArgIle: 2.401 ± 0.013	3.702ArgLys: 3.702 ± 0.016	5.58ArgLeu: 5.58 ± 0.022	1.188ArgMet: 1.188 ± 0.008	2.06ArgAsn: 2.06 ± 0.011	3.497ArgPro: 3.497 ± 0.018	2.668ArgGln: 2.668 ± 0.014	4.509ArgArg: 4.509 ± 0.023	4.379ArgSer: 4.379 ± 0.023	2.894ArgThr: 2.894 ± 0.015	3.266ArgVal: 3.266 ± 0.019	0.724ArgTrp: 0.724 ± 0.007	1.433ArgTyr: 1.433 ± 0.008	0.008ArgXaa: 0.008 ± 0.001
Ser	5.469SerAla: 5.469 ± 0.022	1.842SerCys: 1.842 ± 0.013	3.886SerAsp: 3.886 ± 0.019	5.249SerGlu: 5.249 ± 0.021	2.986SerPhe: 2.986 ± 0.013	5.762SerGly: 5.762 ± 0.022	2.086SerHis: 2.086 ± 0.012	3.086SerIle: 3.086 ± 0.015	4.049SerLys: 4.049 ± 0.02	8.29SerLeu: 8.29 ± 0.025	1.567SerMet: 1.567 ± 0.01	2.552SerAsn: 2.552 ± 0.015	6.264SerPro: 6.264 ± 0.028	3.827SerGln: 3.827 ± 0.019	4.662SerArg: 4.662 ± 0.021	9.194SerSer: 9.194 ± 0.042	4.381SerThr: 4.381 ± 0.021	4.949SerVal: 4.949 ± 0.018	1.095SerTrp: 1.095 ± 0.009	2.01SerTyr: 2.01 ± 0.011	0.008SerXaa: 0.008 ± 0.001
Thr	3.769ThrAla: 3.769 ± 0.015	1.308ThrCys: 1.308 ± 0.015	2.441ThrAsp: 2.441 ± 0.012	3.543ThrGlu: 3.543 ± 0.016	2.075ThrPhe: 2.075 ± 0.011	3.508ThrGly: 3.508 ± 0.017	1.293ThrHis: 1.293 ± 0.01	2.271ThrIle: 2.271 ± 0.014	2.626ThrLys: 2.626 ± 0.015	5.264ThrLeu: 5.264 ± 0.019	1.09ThrMet: 1.09 ± 0.007	1.684ThrAsn: 1.684 ± 0.011	3.635ThrPro: 3.635 ± 0.019	2.264ThrGln: 2.264 ± 0.011	2.509ThrArg: 2.509 ± 0.011	4.561ThrSer: 4.561 ± 0.02	2.847ThrThr: 2.847 ± 0.017	3.872ThrVal: 3.872 ± 0.019	0.695ThrTrp: 0.695 ± 0.01	1.373ThrTyr: 1.373 ± 0.009	0.003ThrXaa: 0.003 ± 0.0
Val	4.33ValAla: 4.33 ± 0.018	1.469ValCys: 1.469 ± 0.011	2.927ValAsp: 2.927 ± 0.014	3.824ValGlu: 3.824 ± 0.02	2.385ValPhe: 2.385 ± 0.014	3.431ValGly: 3.431 ± 0.015	1.558ValHis: 1.558 ± 0.011	2.865ValIle: 2.865 ± 0.015	3.37ValLys: 3.37 ± 0.021	6.293ValLeu: 6.293 ± 0.023	1.295ValMet: 1.295 ± 0.009	2.241ValAsn: 2.241 ± 0.012	3.776ValPro: 3.776 ± 0.023	2.72ValGln: 2.72 ± 0.014	3.173ValArg: 3.173 ± 0.016	4.968ValSer: 4.968 ± 0.022	3.865ValThr: 3.865 ± 0.027	3.987ValVal: 3.987 ± 0.019	0.732ValTrp: 0.732 ± 0.007	1.595ValTyr: 1.595 ± 0.009	0.004ValXaa: 0.004 ± 0.0
Trp	0.813TrpAla: 0.813 ± 0.008	0.245TrpCys: 0.245 ± 0.004	0.651TrpAsp: 0.651 ± 0.007	0.803TrpGlu: 0.803 ± 0.007	0.437TrpPhe: 0.437 ± 0.006	0.781TrpGly: 0.781 ± 0.008	0.307TrpHis: 0.307 ± 0.004	0.524TrpIle: 0.524 ± 0.005	0.801TrpLys: 0.801 ± 0.007	1.214TrpLeu: 1.214 ± 0.01	0.308TrpMet: 0.308 ± 0.004	0.523TrpAsn: 0.523 ± 0.005	0.549TrpPro: 0.549 ± 0.006	0.519TrpGln: 0.519 ± 0.005	0.753TrpArg: 0.753 ± 0.007	0.869TrpSer: 0.869 ± 0.007	0.664TrpThr: 0.664 ± 0.008	0.701TrpVal: 0.701 ± 0.007	0.198TrpTrp: 0.198 ± 0.003	0.337TrpTyr: 0.337 ± 0.005	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.369TyrAla: 1.369 ± 0.01	0.657TyrCys: 0.657 ± 0.007	1.252TyrAsp: 1.252 ± 0.008	1.654TyrGlu: 1.654 ± 0.011	1.204TyrPhe: 1.204 ± 0.009	1.619TyrGly: 1.619 ± 0.011	0.737TyrHis: 0.737 ± 0.006	1.332TyrIle: 1.332 ± 0.011	1.423TyrLys: 1.423 ± 0.014	2.579TyrLeu: 2.579 ± 0.013	0.579TyrMet: 0.579 ± 0.005	1.04TyrAsn: 1.04 ± 0.008	1.257TyrPro: 1.257 ± 0.01	1.242TyrGln: 1.242 ± 0.008	1.568TyrArg: 1.568 ± 0.011	2.122TyrSer: 2.122 ± 0.012	1.442TyrThr: 1.442 ± 0.011	1.576TyrVal: 1.576 ± 0.01	0.342TyrTrp: 0.342 ± 0.005	0.91TyrTyr: 0.91 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.013XaaAla: 0.013 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.003XaaGlu: 0.003 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.013XaaGly: 0.013 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.006XaaLeu: 0.006 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.01XaaPro: 0.01 ± 0.001	0.002XaaGln: 0.002 ± 0.0	0.007XaaArg: 0.007 ± 0.001	0.005XaaSer: 0.005 ± 0.0	0.003XaaThr: 0.003 ± 0.0	0.005XaaVal: 0.005 ± 0.0	0.002XaaTrp: 0.002 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	2.242XaaXaa: 2.242 ± 0.056

Statistics based on 37193 proteins (21738693 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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