Amino acid dipepetide frequency for Colombian potato soil-borne virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.184AlaAla: 7.184 ± 1.528
1.796AlaCys: 1.796 ± 0.358
3.193AlaAsp: 3.193 ± 0.332
6.386AlaGlu: 6.386 ± 0.674
2.395AlaPhe: 2.395 ± 0.556
3.393AlaGly: 3.393 ± 0.445
1.596AlaHis: 1.596 ± 0.408
2.594AlaIle: 2.594 ± 0.559
3.592AlaLys: 3.592 ± 1.056
8.382AlaLeu: 8.382 ± 1.515
0.798AlaMet: 0.798 ± 0.244
2.993AlaAsn: 2.993 ± 0.838
2.395AlaPro: 2.395 ± 0.231
2.993AlaGln: 2.993 ± 0.263
3.991AlaArg: 3.991 ± 1.506
4.789AlaSer: 4.789 ± 0.896
2.794AlaThr: 2.794 ± 0.557
6.785AlaVal: 6.785 ± 1.508
0.399AlaTrp: 0.399 ± 0.164
1.197AlaTyr: 1.197 ± 0.586
0.2AlaXaa: 0.2 ± 0.212
Cys
0.599CysAla: 0.599 ± 0.531
0.998CysCys: 0.998 ± 0.34
0.998CysAsp: 0.998 ± 0.268
1.197CysGlu: 1.197 ± 0.434
0.998CysPhe: 0.998 ± 0.24
2.794CysGly: 2.794 ± 0.718
0.599CysHis: 0.599 ± 0.156
0.0CysIle: 0.0 ± 0.0
1.397CysLys: 1.397 ± 0.373
0.798CysLeu: 0.798 ± 0.534
0.2CysMet: 0.2 ± 0.212
0.599CysAsn: 0.599 ± 0.632
0.399CysPro: 0.399 ± 0.164
1.197CysGln: 1.197 ± 0.402
1.197CysArg: 1.197 ± 0.336
0.599CysSer: 0.599 ± 0.808
0.798CysThr: 0.798 ± 0.37
2.195CysVal: 2.195 ± 0.374
0.0CysTrp: 0.0 ± 0.0
0.599CysTyr: 0.599 ± 0.467
0.0CysXaa: 0.0 ± 0.0
Asp
2.395AspAla: 2.395 ± 0.747
1.996AspCys: 1.996 ± 0.674
6.186AspAsp: 6.186 ± 1.144
4.191AspGlu: 4.191 ± 0.462
2.993AspPhe: 2.993 ± 0.353
3.792AspGly: 3.792 ± 0.759
2.195AspHis: 2.195 ± 0.226
4.191AspIle: 4.191 ± 0.671
3.991AspLys: 3.991 ± 0.559
7.184AspLeu: 7.184 ± 0.812
0.798AspMet: 0.798 ± 0.468
4.39AspAsn: 4.39 ± 0.943
2.794AspPro: 2.794 ± 1.22
1.996AspGln: 1.996 ± 0.884
2.993AspArg: 2.993 ± 0.677
5.388AspSer: 5.388 ± 0.878
3.393AspThr: 3.393 ± 0.666
3.991AspVal: 3.991 ± 0.793
0.0AspTrp: 0.0 ± 0.0
0.998AspTyr: 0.998 ± 0.268
0.0AspXaa: 0.0 ± 0.0
Glu
6.785GluAla: 6.785 ± 1.471
0.599GluCys: 0.599 ± 0.217
5.987GluAsp: 5.987 ± 0.499
5.588GluGlu: 5.588 ± 1.223
1.596GluPhe: 1.596 ± 0.537
4.59GluGly: 4.59 ± 1.076
2.195GluHis: 2.195 ± 0.471
4.59GluIle: 4.59 ± 0.912
5.987GluLys: 5.987 ± 1.354
6.985GluLeu: 6.985 ± 0.625
1.397GluMet: 1.397 ± 0.198
0.998GluAsn: 0.998 ± 0.176
2.794GluPro: 2.794 ± 0.324
1.996GluGln: 1.996 ± 0.806
6.586GluArg: 6.586 ± 1.25
6.586GluSer: 6.586 ± 1.825
2.594GluThr: 2.594 ± 0.356
4.191GluVal: 4.191 ± 0.403
1.197GluTrp: 1.197 ± 0.361
1.596GluTyr: 1.596 ± 0.69
0.0GluXaa: 0.0 ± 0.0
Phe
3.393PheAla: 3.393 ± 0.78
0.599PheCys: 0.599 ± 0.248
5.189PheAsp: 5.189 ± 1.307
1.796PheGlu: 1.796 ± 0.542
2.195PhePhe: 2.195 ± 0.522
3.193PheGly: 3.193 ± 0.632
0.399PheHis: 0.399 ± 0.164
1.397PheIle: 1.397 ± 0.427
2.195PheLys: 2.195 ± 0.648
3.991PheLeu: 3.991 ± 0.524
0.599PheMet: 0.599 ± 0.329
1.397PheAsn: 1.397 ± 0.235
1.197PhePro: 1.197 ± 0.495
1.197PheGln: 1.197 ± 0.287
1.397PheArg: 1.397 ± 0.477
3.592PheSer: 3.592 ± 0.707
2.993PheThr: 2.993 ± 0.577
2.195PheVal: 2.195 ± 0.38
0.2PheTrp: 0.2 ± 0.212
0.998PheTyr: 0.998 ± 0.442
0.0PheXaa: 0.0 ± 0.0
Gly
4.39GlyAla: 4.39 ± 0.995
0.798GlyCys: 0.798 ± 0.433
4.191GlyAsp: 4.191 ± 0.906
5.787GlyGlu: 5.787 ± 0.554
1.596GlyPhe: 1.596 ± 0.858
7.184GlyGly: 7.184 ± 2.283
0.599GlyHis: 0.599 ± 0.272
2.195GlyIle: 2.195 ± 0.369
6.785GlyLys: 6.785 ± 0.559
3.592GlyLeu: 3.592 ± 0.891
3.393GlyMet: 3.393 ± 1.136
4.59GlyAsn: 4.59 ± 1.271
1.796GlyPro: 1.796 ± 0.646
0.798GlyGln: 0.798 ± 0.843
4.191GlyArg: 4.191 ± 1.005
5.588GlySer: 5.588 ± 1.139
1.596GlyThr: 1.596 ± 0.37
4.39GlyVal: 4.39 ± 0.937
0.399GlyTrp: 0.399 ± 0.424
1.397GlyTyr: 1.397 ± 0.291
0.0GlyXaa: 0.0 ± 0.0
His
1.397HisAla: 1.397 ± 0.432
0.399HisCys: 0.399 ± 0.164
1.197HisAsp: 1.197 ± 0.279
1.596HisGlu: 1.596 ± 0.497
0.798HisPhe: 0.798 ± 0.303
1.197HisGly: 1.197 ± 0.526
0.2HisHis: 0.2 ± 0.245
1.197HisIle: 1.197 ± 0.361
0.399HisLys: 0.399 ± 0.322
1.197HisLeu: 1.197 ± 0.434
0.2HisMet: 0.2 ± 0.212
0.399HisAsn: 0.399 ± 0.164
0.399HisPro: 0.399 ± 0.164
0.399HisGln: 0.399 ± 0.398
1.796HisArg: 1.796 ± 0.35
3.792HisSer: 3.792 ± 1.047
0.798HisThr: 0.798 ± 0.297
0.399HisVal: 0.399 ± 0.26
0.399HisTrp: 0.399 ± 0.164
0.399HisTyr: 0.399 ± 0.307
0.0HisXaa: 0.0 ± 0.0
Ile
2.794IleAla: 2.794 ± 0.801
0.599IleCys: 0.599 ± 0.293
4.989IleAsp: 4.989 ± 0.832
3.792IleGlu: 3.792 ± 0.526
1.197IlePhe: 1.197 ± 0.249
1.197IleGly: 1.197 ± 0.379
1.596IleHis: 1.596 ± 0.696
2.993IleIle: 2.993 ± 0.932
2.794IleLys: 2.794 ± 0.941
3.193IleLeu: 3.193 ± 0.649
0.798IleMet: 0.798 ± 0.36
2.195IleAsn: 2.195 ± 0.298
2.594IlePro: 2.594 ± 0.546
1.596IleGln: 1.596 ± 0.493
2.195IleArg: 2.195 ± 0.717
2.395IleSer: 2.395 ± 0.567
3.592IleThr: 3.592 ± 0.746
2.993IleVal: 2.993 ± 0.739
0.0IleTrp: 0.0 ± 0.0
2.195IleTyr: 2.195 ± 0.882
0.0IleXaa: 0.0 ± 0.0
Lys
2.794LysAla: 2.794 ± 0.54
0.399LysCys: 0.399 ± 0.26
3.592LysAsp: 3.592 ± 0.609
4.191LysGlu: 4.191 ± 0.785
1.996LysPhe: 1.996 ± 0.509
4.59LysGly: 4.59 ± 1.271
1.197LysHis: 1.197 ± 0.296
3.193LysIle: 3.193 ± 0.519
5.987LysLys: 5.987 ± 1.399
5.987LysLeu: 5.987 ± 0.892
0.599LysMet: 0.599 ± 0.285
2.594LysAsn: 2.594 ± 0.624
2.794LysPro: 2.794 ± 0.832
2.195LysGln: 2.195 ± 0.451
4.39LysArg: 4.39 ± 0.855
4.789LysSer: 4.789 ± 0.582
3.592LysThr: 3.592 ± 0.486
4.59LysVal: 4.59 ± 0.817
0.0LysTrp: 0.0 ± 0.0
2.993LysTyr: 2.993 ± 0.59
0.2LysXaa: 0.2 ± 0.129
Leu
5.189LeuAla: 5.189 ± 0.405
0.998LeuCys: 0.998 ± 0.403
5.588LeuAsp: 5.588 ± 0.358
4.39LeuGlu: 4.39 ± 0.519
4.59LeuPhe: 4.59 ± 0.695
5.388LeuGly: 5.388 ± 1.499
1.996LeuHis: 1.996 ± 0.588
2.195LeuIle: 2.195 ± 0.853
6.586LeuLys: 6.586 ± 1.38
8.581LeuLeu: 8.581 ± 2.189
2.594LeuMet: 2.594 ± 1.045
4.39LeuAsn: 4.39 ± 0.917
2.794LeuPro: 2.794 ± 0.841
3.592LeuGln: 3.592 ± 0.747
5.987LeuArg: 5.987 ± 1.37
10.178LeuSer: 10.178 ± 1.061
5.987LeuThr: 5.987 ± 0.925
5.987LeuVal: 5.987 ± 0.758
1.197LeuTrp: 1.197 ± 0.447
2.395LeuTyr: 2.395 ± 0.377
0.0LeuXaa: 0.0 ± 0.0
Met
2.794MetAla: 2.794 ± 0.542
0.2MetCys: 0.2 ± 0.212
0.599MetAsp: 0.599 ± 0.3
2.594MetGlu: 2.594 ± 0.63
1.596MetPhe: 1.596 ± 0.645
0.599MetGly: 0.599 ± 0.156
0.0MetHis: 0.0 ± 0.0
0.798MetIle: 0.798 ± 0.37
2.594MetLys: 2.594 ± 0.447
2.594MetLeu: 2.594 ± 0.743
0.2MetMet: 0.2 ± 0.18
0.798MetAsn: 0.798 ± 0.36
0.798MetPro: 0.798 ± 0.36
0.998MetGln: 0.998 ± 0.331
1.197MetArg: 1.197 ± 0.312
0.798MetSer: 0.798 ± 0.334
1.197MetThr: 1.197 ± 0.402
1.796MetVal: 1.796 ± 0.376
0.2MetTrp: 0.2 ± 0.129
0.2MetTyr: 0.2 ± 0.129
0.0MetXaa: 0.0 ± 0.0
Asn
3.792AsnAla: 3.792 ± 0.705
1.796AsnCys: 1.796 ± 0.398
1.596AsnAsp: 1.596 ± 0.432
3.393AsnGlu: 3.393 ± 0.669
1.996AsnPhe: 1.996 ± 0.345
2.993AsnGly: 2.993 ± 0.653
0.2AsnHis: 0.2 ± 0.212
2.195AsnIle: 2.195 ± 0.861
1.397AsnLys: 1.397 ± 0.297
3.393AsnLeu: 3.393 ± 0.969
0.2AsnMet: 0.2 ± 0.129
1.596AsnAsn: 1.596 ± 0.944
1.397AsnPro: 1.397 ± 1.044
0.998AsnGln: 0.998 ± 0.34
2.993AsnArg: 2.993 ± 0.542
3.393AsnSer: 3.393 ± 0.658
2.794AsnThr: 2.794 ± 1.257
3.193AsnVal: 3.193 ± 0.516
1.796AsnTrp: 1.796 ± 0.575
1.596AsnTyr: 1.596 ± 0.269
0.0AsnXaa: 0.0 ± 0.0
Pro
1.796ProAla: 1.796 ± 0.275
0.599ProCys: 0.599 ± 0.332
2.594ProAsp: 2.594 ± 0.354
4.39ProGlu: 4.39 ± 1.107
0.798ProPhe: 0.798 ± 0.297
2.794ProGly: 2.794 ± 0.676
0.599ProHis: 0.599 ± 0.488
2.395ProIle: 2.395 ± 0.407
1.796ProLys: 1.796 ± 0.624
3.991ProLeu: 3.991 ± 1.016
0.798ProMet: 0.798 ± 0.177
0.998ProAsn: 0.998 ± 0.455
0.798ProPro: 0.798 ± 0.297
0.998ProGln: 0.998 ± 0.597
2.395ProArg: 2.395 ± 0.533
1.996ProSer: 1.996 ± 1.113
1.397ProThr: 1.397 ± 0.235
3.193ProVal: 3.193 ± 0.789
0.0ProTrp: 0.0 ± 0.0
1.397ProTyr: 1.397 ± 0.204
0.0ProXaa: 0.0 ± 0.0
Gln
1.796GlnAla: 1.796 ± 0.469
0.399GlnCys: 0.399 ± 0.26
1.996GlnAsp: 1.996 ± 0.709
1.596GlnGlu: 1.596 ± 0.333
0.599GlnPhe: 0.599 ± 0.557
1.796GlnGly: 1.796 ± 0.651
0.0GlnHis: 0.0 ± 0.0
2.594GlnIle: 2.594 ± 0.32
2.395GlnLys: 2.395 ± 0.861
2.594GlnLeu: 2.594 ± 1.537
1.197GlnMet: 1.197 ± 0.405
0.798GlnAsn: 0.798 ± 0.183
0.798GlnPro: 0.798 ± 0.433
1.397GlnGln: 1.397 ± 0.373
1.796GlnArg: 1.796 ± 0.234
3.792GlnSer: 3.792 ± 0.724
1.596GlnThr: 1.596 ± 0.37
2.195GlnVal: 2.195 ± 0.524
0.798GlnTrp: 0.798 ± 0.328
2.594GlnTyr: 2.594 ± 0.587
0.0GlnXaa: 0.0 ± 0.0
Arg
5.189ArgAla: 5.189 ± 0.499
2.195ArgCys: 2.195 ± 0.474
2.993ArgAsp: 2.993 ± 0.368
4.989ArgGlu: 4.989 ± 0.972
2.794ArgPhe: 2.794 ± 0.49
2.395ArgGly: 2.395 ± 0.708
1.596ArgHis: 1.596 ± 0.271
3.193ArgIle: 3.193 ± 0.234
3.792ArgLys: 3.792 ± 0.332
4.989ArgLeu: 4.989 ± 1.323
1.996ArgMet: 1.996 ± 0.756
2.993ArgAsn: 2.993 ± 0.616
2.395ArgPro: 2.395 ± 0.781
1.796ArgGln: 1.796 ± 0.77
4.191ArgArg: 4.191 ± 0.59
3.592ArgSer: 3.592 ± 0.512
2.594ArgThr: 2.594 ± 0.447
3.393ArgVal: 3.393 ± 0.575
0.599ArgTrp: 0.599 ± 0.344
2.395ArgTyr: 2.395 ± 0.48
0.0ArgXaa: 0.0 ± 0.0
Ser
4.989SerAla: 4.989 ± 0.375
1.796SerCys: 1.796 ± 0.709
4.989SerAsp: 4.989 ± 0.995
7.783SerGlu: 7.783 ± 1.298
3.991SerPhe: 3.991 ± 0.844
5.588SerGly: 5.588 ± 0.867
0.599SerHis: 0.599 ± 0.3
3.193SerIle: 3.193 ± 0.629
2.794SerLys: 2.794 ± 0.399
4.989SerLeu: 4.989 ± 1.053
1.397SerMet: 1.397 ± 0.307
2.993SerAsn: 2.993 ± 1.985
3.193SerPro: 3.193 ± 0.761
3.193SerGln: 3.193 ± 0.735
2.993SerArg: 2.993 ± 1.078
6.785SerSer: 6.785 ± 1.967
4.789SerThr: 4.789 ± 0.7
8.182SerVal: 8.182 ± 1.133
2.195SerTrp: 2.195 ± 0.654
2.993SerTyr: 2.993 ± 0.47
0.0SerXaa: 0.0 ± 0.0
Thr
4.59ThrAla: 4.59 ± 1.053
0.399ThrCys: 0.399 ± 0.531
3.592ThrAsp: 3.592 ± 0.233
1.596ThrGlu: 1.596 ± 0.35
1.996ThrPhe: 1.996 ± 0.632
3.592ThrGly: 3.592 ± 1.076
1.996ThrHis: 1.996 ± 0.361
1.996ThrIle: 1.996 ± 0.668
2.395ThrLys: 2.395 ± 0.723
6.186ThrLeu: 6.186 ± 0.681
1.397ThrMet: 1.397 ± 0.694
2.195ThrAsn: 2.195 ± 0.399
1.397ThrPro: 1.397 ± 0.38
1.397ThrGln: 1.397 ± 0.692
3.193ThrArg: 3.193 ± 0.357
3.592ThrSer: 3.592 ± 0.254
2.794ThrThr: 2.794 ± 0.598
4.191ThrVal: 4.191 ± 0.494
0.798ThrTrp: 0.798 ± 0.36
2.594ThrTyr: 2.594 ± 0.915
0.0ThrXaa: 0.0 ± 0.0
Val
6.186ValAla: 6.186 ± 0.892
1.397ValCys: 1.397 ± 0.367
2.395ValAsp: 2.395 ± 0.439
5.987ValGlu: 5.987 ± 0.726
3.792ValPhe: 3.792 ± 0.757
4.989ValGly: 4.989 ± 0.68
0.998ValHis: 0.998 ± 0.296
3.991ValIle: 3.991 ± 0.744
3.592ValLys: 3.592 ± 0.819
6.985ValLeu: 6.985 ± 0.91
1.596ValMet: 1.596 ± 0.669
2.993ValAsn: 2.993 ± 0.492
3.193ValPro: 3.193 ± 0.332
2.594ValGln: 2.594 ± 0.464
3.991ValArg: 3.991 ± 0.442
6.386ValSer: 6.386 ± 1.32
4.39ValThr: 4.39 ± 0.362
9.778ValVal: 9.778 ± 1.038
0.0ValTrp: 0.0 ± 0.0
3.193ValTyr: 3.193 ± 0.885
0.0ValXaa: 0.0 ± 0.0
Trp
0.399TrpAla: 0.399 ± 0.164
0.0TrpCys: 0.0 ± 0.0
0.798TrpAsp: 0.798 ± 0.303
0.599TrpGlu: 0.599 ± 0.248
0.998TrpPhe: 0.998 ± 0.464
0.798TrpGly: 0.798 ± 0.328
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.599TrpLys: 0.599 ± 0.393
0.998TrpLeu: 0.998 ± 0.331
0.998TrpMet: 0.998 ± 0.388
0.798TrpAsn: 0.798 ± 0.177
0.2TrpPro: 0.2 ± 0.332
0.0TrpGln: 0.0 ± 0.0
0.399TrpArg: 0.399 ± 0.398
0.2TrpSer: 0.2 ± 0.129
0.399TrpThr: 0.399 ± 0.398
1.397TrpVal: 1.397 ± 0.559
0.2TrpTrp: 0.2 ± 0.129
0.798TrpTyr: 0.798 ± 0.328
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.596TyrAla: 1.596 ± 0.495
0.2TyrCys: 0.2 ± 0.316
3.193TyrAsp: 3.193 ± 0.637
2.993TyrGlu: 2.993 ± 0.294
1.197TyrPhe: 1.197 ± 0.402
2.395TyrGly: 2.395 ± 0.333
0.0TyrHis: 0.0 ± 0.0
0.798TyrIle: 0.798 ± 0.468
1.596TyrLys: 1.596 ± 0.719
3.991TyrLeu: 3.991 ± 0.411
1.197TyrMet: 1.197 ± 0.492
1.996TyrAsn: 1.996 ± 0.678
1.596TyrPro: 1.596 ± 0.46
1.197TyrGln: 1.197 ± 0.402
1.996TyrArg: 1.996 ± 0.412
1.197TyrSer: 1.197 ± 0.312
1.796TyrThr: 1.796 ± 0.35
3.393TyrVal: 3.393 ± 0.599
0.2TyrTrp: 0.2 ± 0.332
1.397TyrTyr: 1.397 ± 0.602
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.2XaaGln: 0.2 ± 0.212
0.2XaaArg: 0.2 ± 0.129
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (5012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski